Jay S. Desgrosellier, Ph.D. - Publications

Affiliations: 
2004 Vanderbilt University, Nashville, TN 
Area:
Pharmacology, Animal Physiology Biology

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Seguin L, Desgrosellier JS, Weis SM, Cheresh DA. Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance. Trends in Cell Biology. 25: 234-40. PMID 25572304 DOI: 10.1016/j.tcb.2014.12.006  0.32
2014 Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, ... ... Desgrosellier JS, et al. An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nature Cell Biology. 16: 457-68. PMID 24747441 DOI: 10.1038/ncb2953  0.32
2013 Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J. PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes. Proceedings of the National Academy of Sciences of the United States of America. 110: 9042-7. PMID 23671068 DOI: 10.1073/pnas.1219603110  0.32
2012 Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1. Plos One. 7: e36753. PMID 22586492 DOI: 10.1371/journal.pone.0036753  0.32
2010 Shields DJ, Niessen S, Murphy EA, Mielgo A, Desgrosellier JS, Lau SK, Barnes LA, Lesperance J, Bouvet M, Tarin D, Cravatt BF, Cheresh DA. RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. Proceedings of the National Academy of Sciences of the United States of America. 107: 2189-94. PMID 20080647 DOI: 10.1073/pnas.0911646107  0.32
2009 Desgrosellier JS, Barnes LA, Shields DJ, Huang M, Lau SK, Prévost N, Tarin D, Shattil SJ, Cheresh DA. An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nature Medicine. 15: 1163-9. PMID 19734908 DOI: 10.1038/nm.2009  0.32
2006 Park HJ, Ward SM, Desgrosellier JS, Georgescu SP, Papageorge AG, Zhuang X, Barnett JV, Galper JB. Transforming growth factor beta regulates the expression of the M2 muscarinic receptor in atrial myocytes via an effect on RhoA and p190RhoGAP. The Journal of Biological Chemistry. 281: 19995-20002. PMID 16707504 DOI: 10.1074/jbc.M513095200  0.32
2005 Desgrosellier JS, Mundell NA, McDonnell MA, Moses HL, Barnett JV. Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation. Developmental Biology. 280: 201-10. PMID 15766759 DOI: 10.1016/j.ydbio.2004.12.037  0.32
2003 Barnett JV, Desgrosellier JS. Early events in valvulogenesis: a signaling perspective. Birth Defects Research. Part C, Embryo Today : Reviews. 69: 58-72. PMID 12768658 DOI: 10.1002/bdrc.10006  0.32
2002 Ward SM, Desgrosellier JS, Zhuang X, Barnett JV, Galper JB. Transforming growth factor beta (TGFbeta ) signaling via differential activation of activin receptor-like kinases 2 and 5 during cardiac development. Role in regulating parasympathetic responsiveness. The Journal of Biological Chemistry. 277: 50183-9. PMID 12393881 DOI: 10.1074/jbc.M209668200  0.32
2000 Lai YT, Beason KB, Brames GP, Desgrosellier JS, Cleggett MC, Shaw MV, Brown CB, Barnett JV. Activin receptor-like kinase 2 can mediate atrioventricular cushion transformation. Developmental Biology. 222: 1-11. PMID 10885742 DOI: 10.1006/dbio.2000.9698  0.32
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