Linda Wordeman - Publications

University of Washington, Seattle, Seattle, WA 
Molecular Biology, Cell Biology, General Biophysics

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Horne EA, Diaz P, Cimino PJ, Jung E, Xu C, Hamel E, Wagenbach M, Kumasaka D, Wageling NB, Azorín DD, Winkler F, Wordeman LG, Holland EC, Stella N. A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis. Neuro-Oncology Advances. 3: vdaa165. PMID 33506204 DOI: 10.1093/noajnl/vdaa165  0.32
2020 Coombes CE, Saunders HAJ, Mannava AG, Johnson-Schlitz DM, Reid TA, Parmar S, McClellan M, Yan C, Rogers SL, Parrish JZ, Wagenbach M, Wordeman L, Wildonger J, Gardner MK. Non-enzymatic Activity of the α-Tubulin Acetyltransferase αTAT Limits Synaptic Bouton Growth in Neurons. Current Biology : Cb. PMID 31928876 DOI: 10.1016/J.Cub.2019.12.022  0.32
2019 Wagenbach M, Vicente JJ, Ovechkina Y, Domnitz S, Wordeman L. Functional characterization of MCAK/Kif2C cancer mutations using high-throughput microscopic analysis. Molecular Biology of the Cell. mbcE19090503. PMID 31746663 DOI: 10.1091/Mbc.E19-09-0503  0.32
2018 Shen H, Fallas JA, Lynch E, Sheffler W, Parry B, Jannetty N, Decarreau J, Wagenbach M, Vicente JJ, Chen J, Wang L, Dowling Q, Oberdorfer G, Stewart L, Wordeman L, et al. De novo design of self-assembling helical protein filaments. Science (New York, N.Y.). 362: 705-709. PMID 30409885 DOI: 10.2210/Pdb6E9R/Pdb  0.44
2018 Diaz P, Horne E, Xu C, Hamel E, Wagenbach M, Petrov RR, Uhlenbruck B, Haas B, Hothi P, Wordeman L, Gussio R, Stella N. Modified carbazoles destabilize microtubules and kill glioblastoma multiform cells. European Journal of Medicinal Chemistry. 159: 74-89. PMID 30268825 DOI: 10.1016/J.Ejmech.2018.09.026  0.32
2017 Decarreau J, Wagenbach M, Lynch E, Halpern AR, Vaughan JC, Kollman J, Wordeman L. Corrigendum: The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation. Nature Cell Biology. 19: 740. PMID 28561052 DOI: 10.1038/Ncb3546  0.32
2017 Decarreau J, Wagenbach M, Lynch E, Halpern AR, Vaughan JC, Kollman J, Wordeman L. The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation. Nature Cell Biology. PMID 28263957 DOI: 10.1038/Ncb3486  0.32
2016 Luo R, Chen PW, Wagenbach M, Jian X, Jenkins L, Wordeman L, Randazzo PA. Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains 1 (AGAP1). The Journal of Biological Chemistry. 291: 25761. PMID 27913662 DOI: 10.1074/jbc.A116.732479  0.32
2016 Luo R, Chen PW, Wagenbach M, Jian X, Jenkins L, Wordeman L, Randazzo PA. Direct Functional Interaction of the Kinesin-13 family membrane Kinesin Like Protein 2A (Kif2A) and Arf GAP with GTP-Binding Protein-Like, Ankyrin Repeats and PH domains1 (AGAP1). The Journal of Biological Chemistry. PMID 27531749 DOI: 10.1074/Jbc.M116.732479  0.32
2016 Cherry AE, Haas BR, Naydenov AV, Fung S, Xu C, Swinney K, Wagenbach M, Freeling J, Canton DA, Coy J, Horne EA, Rickman B, Vicente JJ, Scott JD, Ho RJ, ... ... Wordeman L, et al. ST-11: a new brain-penetrant microtubule-destabilizing agent with therapeutic potential for glioblastoma multiforme. Molecular Cancer Therapeutics. PMID 27325686 DOI: 10.1158/1535-7163.Mct-15-0800  0.32
2016 Wordeman L, Decarreau J, Vicente JJ, Wagenbach M. Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins. Molecular Biology of the Cell. 27: 1300-9. PMID 26912793 DOI: 10.1091/Mbc.E15-11-0803  0.32
2016 Wordeman L, Decarreau J. Revisiting Actin's role in early centrosome separation. Cell Cycle (Georgetown, Tex.). 15: 162-3. PMID 26701337 DOI: 10.1080/15384101.2015.1130090  0.32
2015 Burns KM, Sarpe V, Wagenbach M, Wordeman L, Schriemer DC. HX-MS2 for high performance conformational analysis of complex protein states. Protein Science : a Publication of the Protein Society. 24: 1313-24. PMID 26009873 DOI: 10.1002/Pro.2707  0.32
2014 Burns KM, Wagenbach M, Wordeman L, Schriemer DC. Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization. Structure (London, England : 1993). 22: 1173-83. PMID 25066134 DOI: 10.1016/J.Str.2014.06.010  0.32
2014 Decarreau J, Driver J, Asbury C, Wordeman L. Rapid measurement of mitotic spindle orientation in cultured mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 1136: 31-40. PMID 24633791 DOI: 10.1007/978-1-4939-0329-0_2  0.32
2012 Stumpff J, Wagenbach M, Franck A, Asbury CL, Wordeman L. Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension. Developmental Cell. 22: 1017-29. PMID 22595673 DOI: 10.1016/J.Devcel.2012.02.013  0.32
2012 Domnitz SB, Wagenbach M, Decarreau J, Wordeman L. MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment. The Journal of Cell Biology. 197: 231-7. PMID 22492725 DOI: 10.1083/Jcb.201108147  0.32
2011 Stumpff J, Du Y, English CA, Maliga Z, Wagenbach M, Asbury CL, Wordeman L, Ohi R. A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A. Molecular Cell. 43: 764-75. PMID 21884977 DOI: 10.1016/J.Molcel.2011.07.022  0.32
2010 Montenegro Gouveia S, Leslie K, Kapitein LC, Buey RM, Grigoriev I, Wagenbach M, Smal I, Meijering E, Hoogenraad CC, Wordeman L, Steinmetz MO, Akhmanova A. In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends. Current Biology : Cb. 20: 1717-22. PMID 20850319 DOI: 10.1016/J.Cub.2010.08.020  0.32
2010 Rankin KE, Wordeman L. Long astral microtubules uncouple mitotic spindles from the cytokinetic furrow. The Journal of Cell Biology. 190: 35-43. PMID 20603328 DOI: 10.1083/Jcb.201004017  1
2010 Cooper JR, Wagenbach M, Asbury CL, Wordeman L. Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK. Nature Structural & Molecular Biology. 17: 77-82. PMID 19966798 DOI: 10.1038/Nsmb.1728  0.32
2009 Peris L, Wagenbach M, Lafanechère L, Brocard J, Moore AT, Kozielski F, Job D, Wordeman L, Andrieux A. Motor-dependent microtubule disassembly driven by tubulin tyrosination. The Journal of Cell Biology. 185: 1159-66. PMID 19564401 DOI: 10.1083/Jcb.200902142  0.32
2009 Mulder AM, Glavis-Bloom A, Moores CA, Wagenbach M, Carragher B, Wordeman L, Milligan RA. A new model for binding of kinesin 13 to curved microtubule protofilaments. The Journal of Cell Biology. 185: 51-7. PMID 19332892 DOI: 10.1083/Jcb.200812052  0.32
2008 Wagenbach M, Domnitz S, Wordeman L, Cooper J. A kinesin-13 mutant catalytically depolymerizes microtubules in ADP. The Journal of Cell Biology. 183: 617-23. PMID 19001124 DOI: 10.1083/Jcb.200805145  0.32
2008 Stumpff J, von Dassow G, Wagenbach M, Asbury C, Wordeman L. The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment. Developmental Cell. 14: 252-62. PMID 18267093 DOI: 10.1016/J.Devcel.2007.11.014  0.32
2007 Wordeman L, Wagenbach M, von Dassow G. MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover. The Journal of Cell Biology. 179: 869-79. PMID 18039936 DOI: 10.1083/Jcb.200707120  0.32
2007 Stumpff J, Cooper J, Domnitz S, Moore AT, Rankin KE, Wagenbach M, Wordeman L. In vitro and in vivo analysis of microtubule-destabilizing kinesins. Methods in Molecular Biology (Clifton, N.J.). 392: 37-49. PMID 17951709 DOI: 10.1007/978-1-59745-490-2_3  1
2007 Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA. The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Molecular Biology of the Cell. 18: 2970-9. PMID 17538014 DOI: 10.1091/Mbc.E07-02-0110  0.32
2006 Moores CA, Cooper J, Wagenbach M, Ovechkina Y, Wordeman L, Milligan RA. The role of the kinesin-13 neck in microtubule depolymerization. Cell Cycle (Georgetown, Tex.). 5: 1812-5. PMID 16929184 DOI: 10.4161/Cc.5.16.3134  0.32
2005 Brown CL, Maier KC, Stauber T, Ginkel LM, Wordeman L, Vernos I, Schroer TA. Kinesin-2 is a motor for late endosomes and lysosomes. Traffic (Copenhagen, Denmark). 6: 1114-24. PMID 16262723 DOI: 10.1111/J.1600-0854.2005.00347.X  0.56
2005 Moore AT, Rankin KE, von Dassow G, Peris L, Wagenbach M, Ovechkina Y, Andrieux A, Job D, Wordeman L. MCAK associates with the tips of polymerizing microtubules. The Journal of Cell Biology. 169: 391-7. PMID 15883193 DOI: 10.1083/Jcb.200411089  1
2004 Newton CN, Wagenbach M, Ovechkina Y, Wordeman L, Wilson L. MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitro. Febs Letters. 572: 80-4. PMID 15304328 DOI: 10.1016/J.Febslet.2004.06.093  0.32
2004 Andrews PD, Ovechkina Y, Morrice N, Wagenbach M, Duncan K, Wordeman L, Swedlow JR. Aurora B regulates MCAK at the mitotic centromere. Developmental Cell. 6: 253-68. PMID 14960279 DOI: 10.1016/S1534-5807(04)00025-5  0.32
2003 Hunter AW, Caplow M, Coy DL, Hancock WO, Diez S, Wordeman L, Howard J. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Molecular Cell. 11: 445-57. PMID 12620232 DOI: 10.1016/S1097-2765(03)00049-2  0.92
2002 Ovechkina Y, Wagenbach M, Wordeman L. K-loop insertion restores microtubule depolymerizing activity of a "neckless" MCAK mutant. The Journal of Cell Biology. 159: 557-62. PMID 12446739 DOI: 10.1083/Jcb.200205089  0.32
2000 Hunter AW, Wordeman L. How motor proteins influence microtubule polymerization dynamics. Journal of Cell Science. 113: 4379-89. PMID 11082031  0.92
2000 Maney T, Ginkel LM, Hunter AW, Wordeman L. The kinetochore of higher eucaryotes: a molecular view. International Review of Cytology. 194: 67-131. PMID 10494625 DOI: 10.1016/S0074-7696(08)62395-5  0.92
1998 Maney T, Hunter AW, Wagenbach M, Wordeman L. Mitotic centromere-associated kinesin is important for anaphase chromosome segregation. The Journal of Cell Biology. 142: 787-801. PMID 9700166 DOI: 10.1083/Jcb.142.3.787  0.92
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