Linda Wordeman - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Molecular Biology, Cell Biology, General Biophysics

38/108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Horne EA, Diaz P, Cimino PJ, Jung E, Xu C, Hamel E, Wagenbach M, Kumasaka D, Wageling NB, Azorín DD, Winkler F, Wordeman LG, Holland EC, Stella N. A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis. Neuro-Oncology Advances. 3: vdaa165. PMID 33506204 DOI: 10.1093/noajnl/vdaa165  0.32
2020 Coombes CE, Saunders HAJ, Mannava AG, Johnson-Schlitz DM, Reid TA, Parmar S, McClellan M, Yan C, Rogers SL, Parrish JZ, Wagenbach M, Wordeman L, Wildonger J, Gardner MK. Non-enzymatic Activity of the α-Tubulin Acetyltransferase αTAT Limits Synaptic Bouton Growth in Neurons. Current Biology : Cb. PMID 31928876 DOI: 10.1016/j.cub.2019.12.022  0.32
2019 Wagenbach M, Vicente JJ, Ovechkina Y, Domnitz S, Wordeman L. Functional characterization of MCAK/Kif2C cancer mutations using high-throughput microscopic analysis. Molecular Biology of the Cell. mbcE19090503. PMID 31746663 DOI: 10.1091/mbc.E19-09-0503  0.32
2018 Shen H, Fallas JA, Lynch E, Sheffler W, Parry B, Jannetty N, Decarreau J, Wagenbach M, Vicente JJ, Chen J, Wang L, Dowling Q, Oberdorfer G, Stewart L, Wordeman L, et al. De novo design of self-assembling helical protein filaments. Science (New York, N.Y.). 362: 705-709. PMID 30409885 DOI: 10.2210/Pdb6E9R/Pdb  0.44
2018 Diaz P, Horne E, Xu C, Hamel E, Wagenbach M, Petrov RR, Uhlenbruck B, Haas B, Hothi P, Wordeman L, Gussio R, Stella N. Modified carbazoles destabilize microtubules and kill glioblastoma multiform cells. European Journal of Medicinal Chemistry. 159: 74-89. PMID 30268825 DOI: 10.1016/j.ejmech.2018.09.026  0.32
2017 Decarreau J, Wagenbach M, Lynch E, Halpern AR, Vaughan JC, Kollman J, Wordeman L. Corrigendum: The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation. Nature Cell Biology. 19: 740. PMID 28561052 DOI: 10.1038/Ncb3546  0.32
2017 Decarreau J, Wagenbach M, Lynch E, Halpern AR, Vaughan JC, Kollman J, Wordeman L. The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation. Nature Cell Biology. PMID 28263957 DOI: 10.1038/Ncb3486  0.32
2016 Luo R, Chen PW, Wagenbach M, Jian X, Jenkins L, Wordeman L, Randazzo PA. Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains 1 (AGAP1). The Journal of Biological Chemistry. 291: 25761. PMID 27913662 DOI: 10.1074/jbc.A116.732479  0.32
2016 Luo R, Chen PW, Wagenbach M, Jian X, Jenkins L, Wordeman L, Randazzo PA. Direct Functional Interaction of the Kinesin-13 family membrane Kinesin Like Protein 2A (Kif2A) and Arf GAP with GTP-Binding Protein-Like, Ankyrin Repeats and PH domains1 (AGAP1). The Journal of Biological Chemistry. PMID 27531749 DOI: 10.1074/jbc.M116.732479  0.32
2016 Cherry AE, Haas BR, Naydenov AV, Fung S, Xu C, Swinney K, Wagenbach M, Freeling J, Canton DA, Coy J, Horne EA, Rickman B, Vicente JJ, Scott JD, Ho RJ, ... ... Wordeman L, et al. ST-11: a new brain-penetrant microtubule-destabilizing agent with therapeutic potential for glioblastoma multiforme. Molecular Cancer Therapeutics. PMID 27325686 DOI: 10.1158/1535-7163.Mct-15-0800  0.32
2016 Wordeman L, Decarreau J, Vicente JJ, Wagenbach M. Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins. Molecular Biology of the Cell. 27: 1300-9. PMID 26912793 DOI: 10.1091/mbc.E15-11-0803  0.32
2016 Wordeman L, Decarreau J. Revisiting Actin's role in early centrosome separation. Cell Cycle (Georgetown, Tex.). 15: 162-3. PMID 26701337 DOI: 10.1080/15384101.2015.1130090  0.32
2015 Burns KM, Sarpe V, Wagenbach M, Wordeman L, Schriemer DC. HX-MS2 for high performance conformational analysis of complex protein states. Protein Science : a Publication of the Protein Society. 24: 1313-24. PMID 26009873 DOI: 10.1002/pro.2707  0.32
2014 Burns KM, Wagenbach M, Wordeman L, Schriemer DC. Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization. Structure (London, England : 1993). 22: 1173-83. PMID 25066134 DOI: 10.1016/j.str.2014.06.010  0.32
2014 Decarreau J, Driver J, Asbury C, Wordeman L. Rapid measurement of mitotic spindle orientation in cultured mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 1136: 31-40. PMID 24633791 DOI: 10.1007/978-1-4939-0329-0_2  0.32
2012 Stumpff J, Wagenbach M, Franck A, Asbury CL, Wordeman L. Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension. Developmental Cell. 22: 1017-29. PMID 22595673 DOI: 10.1016/j.devcel.2012.02.013  0.32
2012 Domnitz SB, Wagenbach M, Decarreau J, Wordeman L. MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment. The Journal of Cell Biology. 197: 231-7. PMID 22492725 DOI: 10.1083/jcb.201108147  0.32
2011 Stumpff J, Du Y, English CA, Maliga Z, Wagenbach M, Asbury CL, Wordeman L, Ohi R. A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A. Molecular Cell. 43: 764-75. PMID 21884977 DOI: 10.1016/J.Molcel.2011.07.022  0.32
2010 Montenegro Gouveia S, Leslie K, Kapitein LC, Buey RM, Grigoriev I, Wagenbach M, Smal I, Meijering E, Hoogenraad CC, Wordeman L, Steinmetz MO, Akhmanova A. In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends. Current Biology : Cb. 20: 1717-22. PMID 20850319 DOI: 10.1016/j.cub.2010.08.020  0.32
2010 Rankin KE, Wordeman L. Long astral microtubules uncouple mitotic spindles from the cytokinetic furrow. The Journal of Cell Biology. 190: 35-43. PMID 20603328 DOI: 10.1083/jcb.201004017  1
2010 Cooper JR, Wagenbach M, Asbury CL, Wordeman L. Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK. Nature Structural & Molecular Biology. 17: 77-82. PMID 19966798 DOI: 10.1038/nsmb.1728  0.32
2009 Peris L, Wagenbach M, Lafanechère L, Brocard J, Moore AT, Kozielski F, Job D, Wordeman L, Andrieux A. Motor-dependent microtubule disassembly driven by tubulin tyrosination. The Journal of Cell Biology. 185: 1159-66. PMID 19564401 DOI: 10.1083/jcb.200902142  0.32
2009 Mulder AM, Glavis-Bloom A, Moores CA, Wagenbach M, Carragher B, Wordeman L, Milligan RA. A new model for binding of kinesin 13 to curved microtubule protofilaments. The Journal of Cell Biology. 185: 51-7. PMID 19332892 DOI: 10.1083/jcb.200812052  0.32
2008 Wagenbach M, Domnitz S, Wordeman L, Cooper J. A kinesin-13 mutant catalytically depolymerizes microtubules in ADP. The Journal of Cell Biology. 183: 617-23. PMID 19001124 DOI: 10.1083/jcb.200805145  0.32
2008 Stumpff J, von Dassow G, Wagenbach M, Asbury C, Wordeman L. The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment. Developmental Cell. 14: 252-62. PMID 18267093 DOI: 10.1016/j.devcel.2007.11.014  0.32
2007 Wordeman L, Wagenbach M, von Dassow G. MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover. The Journal of Cell Biology. 179: 869-79. PMID 18039936 DOI: 10.1083/jcb.200707120  0.32
2007 Stumpff J, Cooper J, Domnitz S, Moore AT, Rankin KE, Wagenbach M, Wordeman L. In vitro and in vivo analysis of microtubule-destabilizing kinesins. Methods in Molecular Biology (Clifton, N.J.). 392: 37-49. PMID 17951709 DOI: 10.1007/978-1-59745-490-2_3  1
2007 Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA. The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Molecular Biology of the Cell. 18: 2970-9. PMID 17538014 DOI: 10.1091/mbc.E07-02-0110  0.32
2006 Moores CA, Cooper J, Wagenbach M, Ovechkina Y, Wordeman L, Milligan RA. The role of the kinesin-13 neck in microtubule depolymerization. Cell Cycle (Georgetown, Tex.). 5: 1812-5. PMID 16929184  0.32
2005 Brown CL, Maier KC, Stauber T, Ginkel LM, Wordeman L, Vernos I, Schroer TA. Kinesin-2 is a motor for late endosomes and lysosomes. Traffic (Copenhagen, Denmark). 6: 1114-24. PMID 16262723 DOI: 10.1111/J.1600-0854.2005.00347.X  0.56
2005 Moore AT, Rankin KE, von Dassow G, Peris L, Wagenbach M, Ovechkina Y, Andrieux A, Job D, Wordeman L. MCAK associates with the tips of polymerizing microtubules. The Journal of Cell Biology. 169: 391-7. PMID 15883193 DOI: 10.1083/jcb.200411089  1
2004 Newton CN, Wagenbach M, Ovechkina Y, Wordeman L, Wilson L. MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitro. Febs Letters. 572: 80-4. PMID 15304328 DOI: 10.1016/J.Febslet.2004.06.093  0.32
2004 Andrews PD, Ovechkina Y, Morrice N, Wagenbach M, Duncan K, Wordeman L, Swedlow JR. Aurora B regulates MCAK at the mitotic centromere. Developmental Cell. 6: 253-68. PMID 14960279  0.32
2003 Hunter AW, Caplow M, Coy DL, Hancock WO, Diez S, Wordeman L, Howard J. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Molecular Cell. 11: 445-57. PMID 12620232 DOI: 10.1016/S1097-2765(03)00049-2  0.92
2002 Ovechkina Y, Wagenbach M, Wordeman L. K-loop insertion restores microtubule depolymerizing activity of a "neckless" MCAK mutant. The Journal of Cell Biology. 159: 557-62. PMID 12446739 DOI: 10.1083/jcb.200205089  0.32
2000 Hunter AW, Wordeman L. How motor proteins influence microtubule polymerization dynamics. Journal of Cell Science. 113: 4379-89. PMID 11082031  0.92
2000 Maney T, Ginkel LM, Hunter AW, Wordeman L. The kinetochore of higher eucaryotes: a molecular view. International Review of Cytology. 194: 67-131. PMID 10494625  0.92
1998 Maney T, Hunter AW, Wagenbach M, Wordeman L. Mitotic centromere-associated kinesin is important for anaphase chromosome segregation. The Journal of Cell Biology. 142: 787-801. PMID 9700166  0.92
Low-probability matches
2011 Mattison CP, Stumpff J, Wordeman L, Winey M. Mip1 associates with both the Mps1 kinase and actin, and is required for cell cortex stability and anaphase spindle positioning Cell Cycle. 10: 783-793. PMID 21325884 DOI: 10.4161/Cc.10.5.14955  0.24
2010 Tien JF, Umbreit NT, Gestaut DR, Franck AD, Cooper J, Wordeman L, Gonen T, Asbury CL, Davis TN. Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B. The Journal of Cell Biology. 189: 713-23. PMID 20479468 DOI: 10.1083/Jcb.200910142  0.24
2010 Gestaut DR, Cooper J, Asbury CL, Davis TN, Wordeman L. Reconstitution and functional analysis of kinetochore subcomplexes. Methods in Cell Biology. 95: 641-56. PMID 20466157 DOI: 10.1016/S0091-679X(10)95032-2  0.24
2009 Wordeman L, Stumpff J. Microtubule length control, a team sport? Developmental Cell. 17: 437-8. PMID 19853556 DOI: 10.1016/j.devcel.2009.10.002  0.24
2009 Powers AF, Franck AD, Gestaut DR, Cooper J, Gracyzk B, Wei RR, Wordeman L, Davis TN, Asbury CL. The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion. Cell. 136: 865-75. PMID 19269365 DOI: 10.1016/j.cell.2008.12.045  0.24
2008 Gestaut DR, Graczyk B, Cooper J, Widlund PO, Zelter A, Wordeman L, Asbury CL, Davis TN. Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation. Nature Cell Biology. 10: 407-14. PMID 18364702 DOI: 10.1038/ncb1702  0.24
2007 Stumpff J, Wordeman L. Chromosome congression: the kinesin-8-step path to alignment. Current Biology : Cb. 17: R326-8. PMID 17470346 DOI: 10.1016/j.cub.2007.03.013  0.24
2020 Rosendo-Pineda MJ, Vicente JJ, Vivas O, Pacheco J, Loza-Huerta A, Sampieri A, Wordeman L, Moreno C, Vaca L. Phosphorylation of NMDA receptors by cyclin B/CDK1 modulates calcium dynamics and mitosis. Communications Biology. 3: 665. PMID 33184446 DOI: 10.1038/s42003-020-01393-3  0.2
2019 Vicente JJ, Wordeman L. The quantification and regulation of microtubule dynamics in the mitotic spindle. Current Opinion in Cell Biology. 60: 36-43. PMID 31108428 DOI: 10.1016/j.ceb.2019.03.017  0.2
2019 Cherry AE, Vicente JJ, Xu C, Morrison RS, Ong SE, Wordeman L, Stella N. GPR124 regulates microtubule assembly, mitotic progression, and glioblastoma cell proliferation. Glia. PMID 31058365 DOI: 10.1002/Glia.23628  0.2
2018 Parker AL, Teo WS, Pandzic E, Vicente JJ, McCarroll JA, Wordeman L, Kavallaris M. β-tubulin carboxy-terminal tails exhibit isotype-specific effects on microtubule dynamics in human gene-edited cells. Life Science Alliance. 1. PMID 30079401 DOI: 10.26508/lsa.201800059  0.2
2015 Vicente JJ, Wordeman L. Mitosis, microtubule dynamics and the evolution of kinesins. Experimental Cell Research. 334: 61-9. PMID 25708751 DOI: 10.1016/j.yexcr.2015.02.010  0.2
2006 Peris L, Thery M, Fauré J, Saoudi Y, Lafanechère L, Chilton JK, Gordon-Weeks P, Galjart N, Bornens M, Wordeman L, Wehland J, Andrieux A, Job D. Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends. The Journal of Cell Biology. 174: 839-49. PMID 16954346 DOI: 10.1083/Jcb.200512058  0.2
2003 Ovechkina Y, Wordeman L. Unconventional motoring: an overview of the Kin C and Kin I kinesins. Traffic (Copenhagen, Denmark). 4: 367-75. PMID 12753646  0.2
2004 Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, ... ... Wordeman L, et al. A standardized kinesin nomenclature. The Journal of Cell Biology. 167: 19-22. PMID 15479732 DOI: 10.1083/Jcb.200408113  0.16
2016 Ritter A, Kreis NN, Louwen F, Wordeman L, Yuan J. Molecular insight into the regulation and function of MCAK. Critical Reviews in Biochemistry and Molecular Biology. 1-18. PMID 27146484 DOI: 10.1080/10409238.2016.1178705  0.12
2016 Drum BM, Yuan C, Li L, Liu Q, Wordeman L, Santana LF. Oxidative stress decreases microtubule growth and stability in ventricular myocytes. Journal of Molecular and Cellular Cardiology. PMID 26902968 DOI: 10.1016/j.yjmcc.2016.02.012  0.12
2015 Hehnly H, Canton D, Bucko P, Langeberg LK, Ogier L, Gelman I, Santana LF, Wordeman L, Scott JD. A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. Elife. 4: e09384. PMID 26406118 DOI: 10.7554/Elife.09384  0.12
2014 Rey M, Sarpe V, Burns KM, Buse J, Baker CA, van Dijk M, Wordeman L, Bonvin AM, Schriemer DC. Mass spec studio for integrative structural biology. Structure (London, England : 1993). 22: 1538-48. PMID 25242457 DOI: 10.1016/j.str.2014.08.013  0.12
2013 Schumpert B, García MG, Wessel GM, Wordeman L, Hille MB. Roles for focal adhesion kinase (FAK) in blastomere abscission and vesicle trafficking during cleavage in the sea urchin embryo. Mechanisms of Development. 130: 290-303. PMID 23313141 DOI: 10.1016/J.Mod.2012.12.003  0.12
2012 Siesser PF, Motolese M, Walker MP, Goldfarb D, Gewain K, Yan F, Kulikauskas RM, Chien AJ, Wordeman L, Major MB. FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. Science Signaling. 5: ra64. PMID 22949735 DOI: 10.1126/scisignal.2002871  0.12
2009 Jiang K, Wang J, Liu J, Ward T, Wordeman L, Davidson A, Wang F, Yao X. TIP150 interacts with and targets MC AK at the microtubule plus ends Embo Reports. 10: 857-865. PMID 19543227 DOI: 10.1038/embor.2009.94  0.12
2007 Davis TN, Wordeman L. Rings, bracelets, sleeves, and chevrons: new structures of kinetochore proteins. Trends in Cell Biology. 17: 377-82. PMID 17766118 DOI: 10.1016/j.tcb.2007.08.001  0.12
2006 Parra MT, Gómez R, Viera A, Page J, Calvente A, Wordeman L, Rufas JS, Suja JA. A perikinetochoric ring defined by MCAK and Aurora-B as a novel centromere domain. Plos Genetics. 2: e84. PMID 16741559 DOI: 10.1371/journal.pgen.0020084  0.12
2001 Maney T, Wagenbach M, Wordeman L. Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin. The Journal of Biological Chemistry. 276: 34753-8. PMID 11466324 DOI: 10.1074/JBC.M106626200  0.12
1998 Faulkner NE, Vig B, Echeverri CJ, Wordeman L, Vallee RB. Localization of motor-related proteins and associated complexes to active, but not inactive, centromeres. Human Molecular Genetics. 7: 671-7. PMID 9499420 DOI: 10.1093/hmg/7.4.671  0.12
1993 Hogan CJ, Wein H, Wordeman L, Scholey JM, Sawin KE, Cande WZ. Inhibition of anaphase spindle elongation in vitro by a peptide antibody that recognizes kinesin motor domain. Proceedings of the National Academy of Sciences of the United States of America. 90: 6611-5. PMID 8341676 DOI: 10.1073/Pnas.90.14.6611  0.12
1986 Wordeman L, McDonald KL, Cande WZ. The distribution of cytoplasmic microtubules throughout the cell cycle of the centric diatom Stephanopyxis turris: their role in nuclear migration and positioning the mitotic spindle during cytokinesis The Journal of Cell Biology. 102: 1688-1698. PMID 3517004 DOI: 10.1083/JCB.102.5.1688  0.12
1986 McDonald KL, Pfister K, Masuda H, Wordeman L, Staiger C, Cande WZ. Comparison of spindle elongation in vivo and in vitro in Stephanopyxis turris Journal of Cell Science. Supplement. 5: 205-227. PMID 3477552 DOI: 10.1242/Jcs.1986.Supplement_5.14  0.12
2009 Cooper JR, Wordeman L. The diffusive interaction of microtubule binding proteins. Current Opinion in Cell Biology. 21: 68-73. PMID 19185482 DOI: 10.1016/j.ceb.2009.01.005  0.08
2001 Ginkel LM, Wordeman L. Expression and partial characterization of kinesin-related proteins in differentiating and adult skeletal muscle. Molecular Biology of the Cell. 11: 4143-58. PMID 11102514 DOI: 10.1091/MBC.11.12.4143  0.08
2000 Wordeman L, Wagenbach M, Maney T. Mutations in the ATP-binding domain affect the subcellular distribution of mitotic centromere-associated kinesin (MCAK). Cell Biology International. 23: 275-86. PMID 10600236 DOI: 10.1006/cbir.1999.0359  0.08
1999 Wordeman L, Wagenbach M. Using antisense technology to study mitosis. Methods in Cell Biology. 61: 245-66. PMID 9891319 DOI: 10.1016/S0091-679X(08)61985-8  0.08
2017 Luo R, Reed CE, Sload JA, Wordeman L, Randazzo PA, Chen PW. Arf GAPs and molecular motors. Small Gtpases. 1-14. PMID 28430047 DOI: 10.1080/21541248.2017.1308850  0.04
2013 Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, ... ... Wordeman L, et al. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 21: 101-6. PMID 23580138 DOI: 10.1007/S10577-013-9347-Y  0.04
2001 Ginkel LM, Wordeman L. Expression cloning with pan kinesin antibodies. Methods in Molecular Biology (Clifton, N.J.). 164: 21-41. PMID 11217609 DOI: 10.1385/1-59259-069-1:21  0.04
2020 Wordeman L. Cell Biology: Social Distancing of Microtubule Ends Increases Their Assembly Rates. Current Biology : Cb. 30: R888-R890. PMID 32750351 DOI: 10.1016/j.cub.2020.06.014  0.01
2020 Bucko PJ, Garcia I, Manocha R, Bhat A, Wordeman L, Scott JD. Gravin-associated kinase signaling networks coordinate γ-tubulin organization at mitotic spindle poles. The Journal of Biological Chemistry. PMID 32732289 DOI: 10.1074/jbc.RA120.014791  0.01
2020 Bucko PJ, Lombard CK, Rathbun L, Bhat A, Garcia I, Wordeman L, Smith FD, Maly DJ, Hehnly H, Scott JD. Subcellular Drug Targeting Illuminates Local Action of Polo‐like kinase 1 and Aurora A During Mitosis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.01916  0.01
2019 Bucko PJ, Lombard CK, Rathbun L, Garcia I, Bhat A, Wordeman L, Smith FD, Maly DJ, Hehnly H, Scott JD. Subcellular drug targeting illuminates local kinase action. Elife. 8. PMID 31872801 DOI: 10.7554/Elife.52220  0.01
2019 Wordeman L. GTP-tubulin loves microtubule plus ends but marries the minus ends. The Journal of Cell Biology. PMID 31427370 DOI: 10.1083/jcb.201908039  0.01
2019 Horne E, Xu C, Vicente J, Cimino PJ, Wagenbach M, Hamel E, Gussio R, Diaz P, Uhlenbruck B, Deckwerth T, Wordeman L, Holland E, Stella N. DDIS-29. BRAIN-PENETRANT MICROTUBULE-TARGETING AGENT, ST-401, KILLS GLIOBLASTOMA THROUGH A NOVEL MECHANISM Neuro-Oncology. 21: vi69-vi69. DOI: 10.1093/Neuonc/Noz175.280  0.01
2018 Stella N, Diaz P, Horne E, Xu C, Hamel E, Wagenbach M, Petrov R, Hass B, Parvinder H, Wordeman L, Gussio R. DDIS-14. MODIFIED CARBAZOLES DESTABILIZE MICROTUBULES AND KILL GLIOBLASTOMA MULTIFORM CELLS Neuro-Oncology. 20: vi72-vi72. DOI: 10.1093/Neuonc/Noy148.293  0.01
2016 Drum B, Yuan C, Li L, Wordeman L, Santana LF. Oxidative Stress in Myocardial Infarction Disrupts Microtubule Trafficking, Reducing Transient Outward Current Density Biophysical Journal. 110: 129a. DOI: 10.1016/J.BPJ.2015.11.741  0.01
2015 Cherry A, Haas B, Naydenov A, Fung S, Xu C, Swinney K, Wagenbach M, Freeling J, Canton D, Coy J, Horne E, Rickman B, Scott J, Ho R, Liggitt D, ... Wordeman L, et al. ATPS-06BRAIN-PENETRANT ALKYLINDOLE COMPOUNDS PROMOTE APOPTOSIS IN GLIOMA CELLS THROUGH MICROTUBULE DESTABILIZATION Neuro-Oncology. 17: v19.2-v19. DOI: 10.1093/Neuonc/Nov204.06  0.01
2014 Ertych N, Stolz A, Stenzinger A, Weichert W, Kaulfuß S, Burfeind P, Aigner A, Wordeman L, Bastians H. Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells. Nature Cell Biology. 16: 779-91. PMID 24976383 DOI: 10.1038/ncb2994  0.01
2012 Canton DA, Keene CD, Swinney K, Langeberg LK, Nguyen V, Pelletier L, Pawson T, Wordeman L, Stella N, Scott JD. Gravin is a transitory effector of polo-like kinase 1 during cell division. Molecular Cell. 48: 547-59. PMID 23063527 DOI: 10.1016/j.molcel.2012.09.002  0.01
2011 Sanhaji M, Friel CT, Wordeman L, Louwen F, Yuan J. Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target. Oncotarget. 2: 935-47. PMID 22249213 DOI: 10.18632/oncotarget.416  0.01
2011 Logue JS, Whiting JL, Tunquist B, Sacks DB, Langeberg LK, Wordeman L, Scott JD. AKAP220 protein organizes signaling elements that impact cell migration. The Journal of Biological Chemistry. 286: 39269-81. PMID 21890631 DOI: 10.1074/jbc.M111.277756  0.01
2010 Vogt E, Sanhaji M, Klein W, Seidel T, Wordeman L, Eichenlaub-Ritter U. MCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes. Molecular Human Reproduction. 16: 665-84. PMID 20406800 DOI: 10.1093/molehr/gaq025  0.01
2010 Wordeman L. How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays. Seminars in Cell & Developmental Biology. 21: 260-8. PMID 20109570 DOI: 10.1016/j.semcdb.2010.01.018  0.01
2010 Lombardo K, Stumpff J, Parkhurst S, Wordeman L, Shimamura A. Mitotic Spindle Dysfunction Promotes Genomic Instability In Marrow Failure Blood. 116: 880-880. DOI: 10.1182/BLOOD.V116.21.880.880  0.01
2010 Clarke H, Shalom-Paz E, Streiff AKM, El-Khabouri S, Mahrous E, Demeestere I, Eichenlaub-Ritter U, Klein W, Staubach N, Vogt E, Sanhaij M, Seidel T, Wordeman L, Sjoblom P, Friden B, et al. Session 68: Oocyte Maturation Human Reproduction. 25: i111-i114. DOI: 10.1093/humrep/de.25.s1.68  0.01
2009 Franck AD, Powers AF, Gestaut DR, Cooper J, Gracyzk B, Wei RR, Wordeman L, Davis TN, Asbury CL. Reconstitution Of Microtubule-driven Movement and Force Production by the Ndc80 Kinetochore Complex Biophysical Journal. 96: 572a. DOI: 10.1016/j.bpj.2008.12.3744  0.01
2005 Wordeman L. Microtubule-depolymerizing kinesins. Current Opinion in Cell Biology. 17: 82-8. PMID 15661523 DOI: 10.1016/j.ceb.2004.12.003  0.01
2004 Moore A, Wordeman L. The mechanism, function and regulation of depolymerizing kinesins during mitosis. Trends in Cell Biology. 14: 537-46. PMID 15450976 DOI: 10.1016/j.tcb.2004.09.001  0.01
2004 Moore A, Wordeman L. C-terminus of mitotic centromere-associated kinesin (MCAK) inhibits its lattice-stimulated ATPase activity. The Biochemical Journal. 383: 227-35. PMID 15250824 DOI: 10.1042/BJ20040736  0.01
2003 Wordeman L. Breathing down the neck of Unc104. The Journal of Cell Biology. 163: 693-5. PMID 14638852 DOI: 10.1083/jcb.200310137  0.01
2000 Saffery R, Irvine DV, Griffiths B, Kalitsis P, Wordeman L, Choo KH. Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins. Human Molecular Genetics. 9: 175-85. PMID 10607828 DOI: 10.1093/HMG/9.2.175  0.01
1999 Wordeman L. Green fluorescent protein Cell Biology International. 23: 523. DOI: 10.1006/CBIR.1999.0372  0.01
1998 Wordeman L. Mechanisms of chromosome segregation in metazoan cells. Progress in Cell Cycle Research. 1: 319-27. PMID 9552374 DOI: 10.1007/978-1-4615-1809-9_26  0.01
1996 Wordeman L, Earnshaw WC, Bernat RL. Disruption of CENP antigen function perturbs dynein anchoring to the mitotic kinetochore. Chromosoma. 104: 551-60. PMID 8662248 DOI: 10.1007/Bf00352295  0.01
1995 Wordeman L, Mitchison TJ. Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. The Journal of Cell Biology. 128: 95-104. PMID 7822426 DOI: 10.1083/Jcb.128.1.95  0.01
1993 Wordeman L. Microtubule motors associated with kinetochores in mitotic cells Proceedings, Annual Meeting, Electron Microscopy Society of America. 51: 76-77. DOI: 10.1017/S0424820100146229  0.01
1991 Hyman A, Drechsel D, Kellogg D, Salser S, Sawin K, Steffen P, Wordeman L, Mitchison T. Preparation of modified tubulins. Methods in Enzymology. 196: 478-85. PMID 2034137 DOI: 10.1016/0076-6879(91)96041-O  0.01
1991 Wordeman L, Steuer ER, Sheetz MP, Mitchison T. Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes. The Journal of Cell Biology. 114: 285-94. PMID 1830054 DOI: 10.1083/Jcb.114.2.285  0.01
1990 Wordeman L, Cande WZ. Cytokinesis by furrowing in diatoms. Annals of the New York Academy of Sciences. 582: 252-9. PMID 2192599 DOI: 10.1111/j.1749-6632.1990.tb21684.x  0.01
1990 Steuer ER, Wordeman L, Schroer TA, Sheetz MP. Localization of cytoplasmic dynein to mitotic spindles and kinetochores. Nature. 345: 266-8. PMID 2139718 DOI: 10.1038/345266A0  0.01
1989 Wordeman L, Davis FM, Rao PN, Cande WZ. Distribution of phosphorylated spindle-associated proteins in the diatom Stephanopyxis turris. Cell Motility and the Cytoskeleton. 12: 33-41. PMID 2650886 DOI: 10.1002/cm.970120105  0.01
1987 Wordeman L, Cande WZ. Reactivation of spindle elongation in vitro is correlated with the phosphorylation of a 205 kd spindle-associated protein Cell. 50: 535-543. PMID 3038336 DOI: 10.1016/0092-8674(87)90026-2  0.01
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