☰

Stephen Lee - Publications

Affiliations: 
University of Ottawa, Ottawa, ON, Canada 
Area:
VHL, hypoxia
Website:
http://www.med.uottawa.ca/nsc/eng/lee.html
Tree Info Similar researchers PubMed Report error

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Abraham KJ, Khosraviani N, Chan JNY, Gorthi A, Samman A, Zhao DY, Wang M, Bokros M, Vidya E, Ostrowski LA, Oshidari R, Pietrobon V, Patel PS, Algouneh A, Singhania R, ... ... Lee S, et al. Nucleolar RNA polymerase II drives ribosome biogenesis. Nature. PMID 32669707 DOI: 10.1038/S41586-020-2497-0  0.66
2020 Ho JJD, Balukoff NC, Theodoridis PR, Wang M, Krieger JR, Schatz JH, Lee S. A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism. Nature Communications. 11: 2677. PMID 32472050 DOI: 10.1038/S41467-020-16504-1  0.402
2019 Wang M, Bokros M, Theodoridis PR, Lee S. Nucleolar Sequestration: Remodeling Nucleoli Into Amyloid Bodies. Frontiers in Genetics. 10: 1179. PMID 31824572 DOI: 10.3389/Fgene.2019.01179  0.305
2018 Wang M, Tao X, Jacob MD, Bennett CA, Ho JJD, Gonzalgo ML, Audas TE, Lee S. Stress-Induced Low Complexity RNA Activates Physiological Amyloidogenesis. Cell Reports. 24: 1713-1721.e4. PMID 30110628 DOI: 10.1016/J.Celrep.2018.07.040  0.31
2018 Ho JJD, Balukoff NC, Cervantes G, Malcolm PD, Krieger JR, Lee S. Oxygen-Sensitive Remodeling of Central Carbon Metabolism by Archaic eIF5B. Cell Reports. 22: 17-26. PMID 29298419 DOI: 10.1016/J.Celrep.2017.12.031  0.404
2016 Audas TE, Audas DE, Jacob MD, Ho JJ, Khacho M, Wang M, Perera JK, Gardiner C, Bennett CA, Head T, Kryvenko ON, Jorda M, Daunert S, Malhotra A, Trinkle-Mulcahy L, ... ... Lee S, et al. Adaptation to Stressors by Systemic Protein Amyloidogenesis. Developmental Cell. PMID 27720612 DOI: 10.1016/J.Devcel.2016.09.002  0.364
2016 Ho JJ, Lee S. A Cap for Every Occasion: Alternative eIF4F Complexes. Trends in Biochemical Sciences. PMID 27283511 DOI: 10.1016/J.Tibs.2016.05.009  0.34
2016 Ho JJ, Wang M, Audas TE, Kwon D, Carlsson SK, Timpano S, Evagelou SL, Brothers S, Gonzalgo ML, Krieger JR, Chen S, Uniacke J, Lee S. Systemic Reprogramming of Translation Efficiencies on Oxygen Stimulus. Cell Reports. PMID 26854219 DOI: 10.1016/J.Celrep.2016.01.036  0.313
2015 Audas TE, Lee S. Stressing out over long noncoding RNA. Biochimica Et Biophysica Acta. PMID 26142536 DOI: 10.1016/J.Bbagrm.2015.06.010  0.364
2014 Lachance G, Uniacke J, Audas TE, Holterman CE, Franovic A, Payette J, Lee S. DNMT3a epigenetic program regulates the HIF-2α oxygen-sensing pathway and the cellular response to hypoxia. Proceedings of the National Academy of Sciences of the United States of America. 111: 7783-8. PMID 24817692 DOI: 10.1073/Pnas.1322909111  0.422
2014 Tessier SN, Audas TE, Wu CW, Lee S, Storey KB. The involvement of mRNA processing factors TIA-1, TIAR, and PABP-1 during mammalian hibernation. Cell Stress & Chaperones. 19: 813-25. PMID 24590458 DOI: 10.1007/S12192-014-0505-8  0.372
2014 Uniacke J, Perera JK, Lachance G, Francisco CB, Lee S. Cancer cells exploit eIF4E2-directed synthesis of hypoxia response proteins to drive tumor progression. Cancer Research. 74: 1379-89. PMID 24408918 DOI: 10.1158/0008-5472.Can-13-2278  0.43
2013 Jacob MD, Audas TE, Uniacke J, Trinkle-Mulcahy L, Lee S. Environmental cues induce a long noncoding RNA-dependent remodeling of the nucleolus. Molecular Biology of the Cell. 24: 2943-53. PMID 23904269 DOI: 10.1091/Mbc.E13-04-0223  0.356
2012 Uniacke J, Holterman CE, Lachance G, Franovic A, Jacob MD, Fabian MR, Payette J, Holcik M, Pause A, Lee S. An oxygen-regulated switch in the protein synthesis machinery. Nature. 486: 126-9. PMID 22678294 DOI: 10.1038/Nature11055  0.68
2012 Audas TE, Jacob MD, Lee S. The nucleolar detention pathway: A cellular strategy for regulating molecular networks Cell Cycle. 11: 2059-2062. PMID 22580471 DOI: 10.4161/Cc.20140  0.374
2012 Audas TE, Jacob MD, Lee S. Immobilization of Proteins in the Nucleolus by Ribosomal Intergenic Spacer Noncoding RNA Molecular Cell. 45: 147-157. PMID 22284675 DOI: 10.1016/J.Molcel.2011.12.012  0.383
2012 Jacob MD, Audas TE, Mullineux ST, Lee S. Where no RNA polymerase has gone before: Novel functional transcripts derived from the ribosomal intergenic spacer Nucleus (United States). 3: 5. DOI: 10.4161/Nucl.20585  0.341
2011 Feige E, Yokoyama S, Levy C, Khaled M, Igras V, Lin RJ, Lee S, Widlund HR, Granter SR, Kung AL, Fisher DE. Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF. Proceedings of the National Academy of Sciences of the United States of America. 108: E924-33. PMID 21949374 DOI: 10.1073/Pnas.1106351108  0.404
2010 Holterman CE, Franovic A, Payette J, Lee S. ETS-1 oncogenic activity mediated by transforming growth factor α Cancer Research. 70: 730-740. PMID 20068146 DOI: 10.1158/0008-5472.Can-09-2090  0.378
2009 Franovic A, Holterman CE, Payette J, Lee S. Human cancers converge at the HIF-2α oncogenic axis Proceedings of the National Academy of Sciences of the United States of America. 106: 21306-21311. PMID 19955413 DOI: 10.1073/Pnas.0906432106  0.409
2009 Khacho M, Lee S. Subcellular dynamics of the VHL tumor suppressor: On the move for HIF degradation Future Oncology. 5: 85-95. PMID 19243301 DOI: 10.2217/14796694.5.1.85  0.45
2009 Pelletier S, Tanguay S, Lee S, Gunaratnam L, Arbour N, Lapointe R. TGF-alpha as a candidate tumor antigen for renal cell carcinomas Cancer Immunology, Immunotherapy. 58: 1207-1218. PMID 19052740 DOI: 10.1007/S00262-008-0630-2  0.666
2008 Khacho M, Mekhail K, Pilon-Larose K, Pause A, Côté J, Lee S. eEF1A is a novel component of the mammalian nuclear protein export machinery. Molecular Biology of the Cell. 19: 5296-308. PMID 18799616 DOI: 10.1091/Mbc.E08-06-0562  0.751
2008 Khacho M, Mekhail K, Pilon-Larose K, Payette J, Lee S. Cancer-causing mutations in a novel transcription-dependent nuclear export motif of VHL abrogate oxygen-dependent degradation of hypoxia-inducible factor. Molecular and Cellular Biology. 28: 302-14. PMID 17967880 DOI: 10.1128/Mcb.01044-07  0.693
2007 Franovic A, Gunaratnam L, Smith K, Robert I, Patten D, Lee S. Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer Proceedings of the National Academy of Sciences of the United States of America. 104: 13092-13097. PMID 17670948 DOI: 10.1073/Pnas.0702387104  0.665
2007 Mekhail K, Rivero-Lopez L, Al-Masri A, Brandon C, Khacho M, Lee S. Identification of a common subnuclear localization signal. Molecular Biology of the Cell. 18: 3966-77. PMID 17652456 DOI: 10.1091/Mbc.E07-03-0295  0.667
2006 Mekhail K, Rivero-Lopez L, Khacho M, Lee S. Restriction of rRNA synthesis by VHL maintains energy equilibrium under hypoxia. Cell Cycle (Georgetown, Tex.). 5: 2401-13. PMID 17102617 DOI: 10.4161/Cc.5.20.3387  0.684
2006 Franovic A, Robert I, Smith K, Kurban G, Pause A, Gunaratnam L, Lee S. Multiple acquired renal carcinoma tumor capabilities abolished upon silencing of ADAM17. Cancer Research. 66: 8083-90. PMID 16912185 DOI: 10.1158/0008-5472.Can-06-1595  0.749
2005 Mekhail K, Khacho M, Carrigan A, Hache RR, Gunaratnam L, Lee S. Regulation of ubiquitin ligase dynamics by the nucleolus. The Journal of Cell Biology. 170: 733-44. PMID 16129783 DOI: 10.1083/Jcb.200506030  0.752
2005 Smith K, Gunaratnam L, Morley M, Franovic A, Mekhail K, Lee S. Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer. Cancer Research. 65: 5221-30. PMID 15958567 DOI: 10.1158/0008-5472.Can-05-0169  0.775
2004 Mekhail K, Khacho M, Gunaratnam L, Lee S. Oxygen sensing by H+: implications for HIF and hypoxic cell memory. Cell Cycle (Georgetown, Tex.). 3: 1027-9. PMID 15280664 DOI: 10.4161/Cc.3.8.1075  0.761
2004 Mekhail K, Gunaratnam L, Bonicalzi ME, Lee S. HIF activation by pH-dependent nucleolar sequestration of VHL. Nature Cell Biology. 6: 642-7. PMID 15181450 DOI: 10.1038/Ncb1144  0.758
2003 Gunaratnam L, Morley M, Franovic A, de Paulsen N, Mekhail K, Parolin DA, Nakamura E, Lorimer IA, Lee S. Hypoxia inducible factor activates the transforming growth factor-alpha/epidermal growth factor receptor growth stimulatory pathway in VHL(-/-) renal cell carcinoma cells. The Journal of Biological Chemistry. 278: 44966-74. PMID 12944410 DOI: 10.1074/Jbc.M305502200  0.769
2003 Walther RF, Lamprecht C, Ridsdale A, Groulx I, Lee S, Lefebvre YA, Haché RJG. Nuclear export of the glucocorticoid receptor is accelerated by cell fusion-dependent release of calreticulin Journal of Biological Chemistry. 278: 37858-37864. PMID 12869547 DOI: 10.1074/Jbc.M306356200  0.343
2002 Groulx I, Lee S. Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein Molecular and Cellular Biology. 22: 5319-5336. PMID 12101228 DOI: 10.1128/MCB.22.15.5319-5336.2002  0.327
2001 de Paulsen N, Brychzy A, Fournier MC, Klausner RD, Gnarra JR, Pause A, Lee S. Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 98: 1387-92. PMID 11171960 DOI: 10.1073/Pnas.031587498  0.731
2001 Bonicalzi ME, Groulx I, De Paulsen N, Lee S. Role of exon 2-encoded β-domain of the von Hippel-Lindau tumor suppressor protein Journal of Biological Chemistry. 276: 1407-1416. PMID 11024059 DOI: 10.1074/Jbc.M008295200  0.415
2000 Groulx I, Bonicalzi ME, Lee S. Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2 Journal of Biological Chemistry. 275: 8991-9000. PMID 10722748 DOI: 10.1074/Jbc.275.12.8991  0.43
Show low-probability matches.