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Xihong Wang, Ph.D. - Publications

Affiliations: 
2005 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmaceutical Chemistry, Oncology
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Wang SB, Cui MT, Wang XF, Ohkoshi E, Goto M, Yang DX, Li L, Yuan S, Morris-Natschke SL, Lee KH, Xie L. Synthesis, biological evaluation, and physicochemical property assessment of 4-substituted 2-phenylaminoquinazolines as Mer tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry. PMID 27238842 DOI: 10.1016/j.bmc.2016.05.025  0.618
2015 Wang SB, Wang XF, Qin B, Ohkoshi E, Hsieh KY, Hamel E, Cui MT, Zhu DQ, Goto M, Morris-Natschke SL, Lee KH, Xie L. Optimization of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines as tubulin polymerization inhibitors. Bioorganic & Medicinal Chemistry. PMID 26242242 DOI: 10.1016/j.bmc.2015.07.016  0.614
2014 Li RJ, Sun Y, Sun B, Wang XN, Liu SS, Zhou JC, Ye JP, Zhao Y, Liu L, Lee KH, Lou HX. Phytotoxic cis-clerodane diterpenoids from the Chinese liverwort Scapania stephanii. Phytochemistry. 105: 85-91. PMID 24947338 DOI: 10.1016/j.phytochem.2014.05.019  0.503
2014 Wang XF, Guan F, Ohkoshi E, Guo W, Wang L, Zhu DQ, Wang SB, Wang LT, Hamel E, Yang D, Li L, Qian K, Morris-Natschke SL, Yuan S, Lee KH, et al. Optimization of 4-(N-cycloamino)phenylquinazolines as a novel class of tubulin-polymerization inhibitors targeting the colchicine site. Journal of Medicinal Chemistry. 57: 1390-402. PMID 24502232 DOI: 10.1021/Jm4016526  0.606
2013 Wang XF, Wang SB, Ohkoshi E, Wang LT, Hamel E, Qian K, Morris-Natschke SL, Lee KH, Xie L. N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines: a novel class of antitumor agents targeting the colchicine site on tubulin. European Journal of Medicinal Chemistry. 67: 196-207. PMID 23867604 DOI: 10.1016/J.Ejmech.2013.06.041  0.644
2013 Li WQ, Wang XL, Qian K, Liu YQ, Wang CY, Yang L, Tian J, Morris-Natschke SL, Zhou XW, Lee KH. Design, synthesis and potent cytotoxic activity of novel podophyllotoxin derivatives. Bioorganic & Medicinal Chemistry. 21: 2363-9. PMID 23490151 DOI: 10.1016/J.Bmc.2013.01.069  0.619
2013 Wang XF, Ohkoshi E, Wang SB, Hamel E, Bastow KF, Morris-Natschke SL, Lee KH, Xie L. Synthesis and biological evaluation of N-alkyl-N-(4-methoxyphenyl)pyridin-2-amines as a new class of tubulin polymerization inhibitors. Bioorganic & Medicinal Chemistry. 21: 632-42. PMID 23274123 DOI: 10.1016/j.bmc.2012.11.047  0.612
2012 Wang XF, Tian XT, Ohkoshi E, Qin B, Liu YN, Wu PC, Hour MJ, Hung HY, Qian K, Huang R, Bastow KF, Janzen WP, Jin J, Morris-Natschke SL, Lee KH, et al. Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents. Bioorganic & Medicinal Chemistry Letters. 22: 6224-8. PMID 22932313 DOI: 10.1016/J.Bmcl.2012.08.014  0.623
2011 Soares J, Keppler BR, Wang X, Lee KH, Jarstfer MB. ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide. Bioorganic & Medicinal Chemistry Letters. 21: 7474-8. PMID 22044621 DOI: 10.1016/J.Bmcl.2011.09.112  0.51
2011 Liu X, Wang X, Li Q, Kozar MP, Melendez V, O'Neil MT, Lin AJ. Synthesis and antimalarial activity of 2-guanidino-4-oxoimidazoline derivatives. Journal of Medicinal Chemistry. 54: 4523-35. PMID 21627120 DOI: 10.1021/jm200111g  0.323
2011 Xie BB, Shang MY, Wang X, Cai SQ, Lee KH. [A new aristolochic acid derivative from Asarum himalaicum]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 46: 188-92. PMID 21542290  0.519
2011 Xie BB, Shang MY, Lee KH, Wang X, Komatsu K, Cai SQ. 5-methoxyaristololactam I, the first natural 5-substituted aristololactam from Asarum ichangense. Natural Product Communications. 6: 11-4. PMID 21366036  0.564
2010 Tian X, Qin B, Wu Z, Wang X, Lu H, Morris-Natschke SL, Chen CH, Jiang S, Lee KH, Xie L. Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Journal of Medicinal Chemistry. 53: 8287-97. PMID 21049929 DOI: 10.1021/jm100738d  0.58
2009 Dong Y, Shi Q, Liu YN, Wang X, Bastow KF, Lee KH. Antitumor agents. 266. Design, synthesis, and biological evaluation of novel 2-(furan-2-yl)naphthalen-1-ol derivatives as potent and selective antibreast cancer agents. Journal of Medicinal Chemistry. 52: 3586-90. PMID 19425534 DOI: 10.1021/Jm9001567  0.599
2008 Magalhães R, Wang XW, Gouk SS, Lee KH, Ten CM, Yu H, Kuleshova LL. Vitrification successfully preserves hepatocyte spheroids. Cell Transplantation. 17: 813-28. PMID 19044208 DOI: 10.3727/096368908786516765  0.465
2007 Guan J, Wang X, Smith K, Ager A, Gettayacamin M, Kyle DE, Milhous WK, Kozar MP, Magill AJ, Lin AJ. Malaria causal prophylactic activity of imidazolidinedione derivatives. Journal of Medicinal Chemistry. 50: 6226-31. PMID 17967003 DOI: 10.1021/Jm7009815  0.302
2007 Wang X, Morris-Natschke SL, Lee KH. New developments in the chemistry and biology of the bioactive constituents of Tanshen. Medicinal Research Reviews. 27: 133-48. PMID 16888751 DOI: 10.1002/med.20077  0.584
2006 Kwon YC, Yun YH, Lee KH, Son KY, Park SM, Chang YJ, Wang XS, Mendoza TR, Cleeland CS. Symptoms in the lives of terminal cancer patients: which is the most important? Oncology. 71: 69-76. PMID 17344672 DOI: 10.1159/000100450  0.447
2006 Wang X, Nakagawa-Goto K, Bastow KF, Don MJ, Lin YL, Wu TS, Lee KH. Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents. Journal of Medicinal Chemistry. 49: 5631-4. PMID 16942038 DOI: 10.1021/Jm060184D  0.647
2006 Sakurai Y, Sakurai N, Taniguchi M, Nakanishi Y, Bastow KF, Wang X, Cragg GM, Lee KH. Rautandiols A and B, pterocarpans and cytotoxic constituents from Neorautanenia mitis. Journal of Natural Products. 69: 397-9. PMID 16562843 DOI: 10.1021/Np058070C  0.638
2006 Wang X, Nakagawa-Goto K, Kozuka M, Tokuda H, Nishino H, Lee K. Cancer preventive agents. Part 6: Chemopreventive potential of furanocoumarins and related compounds Pharmaceutical Biology. 44: 116-120. DOI: 10.1080/13880200600592178  0.455
2004 Wang X, Bastow KF, Sun CM, Lin YL, Yu HJ, Don MJ, Wu TS, Nakamura S, Lee KH. Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza. Journal of Medicinal Chemistry. 47: 5816-9. PMID 15509181 DOI: 10.1021/Jm040112R  0.616
2004 Wang YH, Hou AJ, Chen L, Chen DF, Sun HD, Zhao QS, Bastow KF, Nakanish Y, Wang XH, Lee KH. New isoprenylated flavones, artochamins A--E, and cytotoxic principles from Artocarpus chama. Journal of Natural Products. 67: 757-61. PMID 15165133 DOI: 10.1021/np030467y  0.568
2004 Ding P, Chen D, Bastow KF, Nyarko AK, Wang X, Lee KH. Cytotoxic isoprenylated flavonoids from the roots of Sophora flavescens Helvetica Chimica Acta. 87: 2574-2580. DOI: 10.1002/Hlca.200490230  0.439
2003 Wu JH, Wang XH, Yi YH, Lee KH. Anti-AIDS agents 54. A potent anti-HIV chalcone and flavonoids from genus Desmos. Bioorganic & Medicinal Chemistry Letters. 13: 1813-5. PMID 12729671 DOI: 10.1016/S0960-894X(03)00197-5  0.532
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