Kalina A. Hristova - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
General Biophysics, Pathology

162 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hristova K, Wimley WC. Determining the statistical significance of the difference between arbitrary curves: A spreadsheet method. Plos One. 18: e0289619. PMID 37906570 DOI: 10.1371/journal.pone.0289619  0.463
2023 McKenzie DM, Wirth D, Pogorelov TV, Hristova K. Utility of FRET in studies of membrane protein oligomerization: The concept of the effective dissociation constant. Biophysical Journal. 122: 4113-4120. PMID 37735871 DOI: 10.1016/j.bpj.2023.09.011  0.316
2022 Wirth D, Paul MD, Pasquale EB, Hristova K. Direct quantification of ligand-induced lipid and protein microdomains with distinctive signaling properties. Chemsystemschem. 4. PMID 36337751 DOI: 10.1002/syst.202200011  0.313
2022 Zapata-Mercado E, Biener G, McKenzie DM, Wimley WC, Pasquale EB, Raicu V, Hristova K. The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size. The Journal of Biological Chemistry. 102370. PMID 35970390 DOI: 10.1016/j.jbc.2022.102370  0.523
2021 Guha S, Ferrie RP, Ghimire J, Ventura C, Wu E, Sun L, Kim SY, Wiedman GR, Hristova K, Wimley WC. Applications and evolution of melittin, the quintessential membrane active peptide. Biochemical Pharmacology. 114769. PMID 34543656 DOI: 10.1016/j.bcp.2021.114769  0.832
2021 Wirth D, Özdemir E, King C, Ahlswede L, Schneider D, Hristova K. Quantitative characterization of Tetraspanin 8 homointeractions in the plasma membrane. The Biochemical Journal. PMID 34524408 DOI: 10.1042/BCJ20210459  0.323
2021 Sun L, Hristova K, Wimley WC. Membrane-selective nanoscale pores in liposomes by a synthetically evolved peptide: implications for triggered release. Nanoscale. PMID 34190297 DOI: 10.1039/d1nr03084a  0.675
2021 Kim SY, Bondar AN, Wimley WC, Hristova K. pH-triggered pore-forming peptides with strong composition-dependent membrane selectivity. Biophysical Journal. PMID 33460594 DOI: 10.1016/j.bpj.2021.01.010  0.805
2020 Wu E, Jenschke RM, Hristova K, Wimley WC. Rational Modulation of pH-triggered Macromolecular Poration by Peptide Acylation and Dimerization. The Journal of Physical Chemistry. B. PMID 32892626 DOI: 10.1021/Acs.Jpcb.0C05363  0.697
2020 Byrne PO, Hristova K, Leahy DJ. EGFR forms ligand-independent oligomers that are distinct from the active state. The Journal of Biological Chemistry. PMID 32727847 DOI: 10.1074/Jbc.Ra120.012852  0.357
2020 Komin A, Bogorad MI, Lin R, Cui H, Searson PC, Hristova K. A peptide for transcellular cargo delivery: Structure-function relationship and mechanism of action. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32474121 DOI: 10.1016/J.Jconrel.2020.05.030  0.446
2020 Paul MD, Grubb HN, Hristova K. Quantifying the strength of heterointeractions among receptor tyrosine kinases from different subfamilies: Implications for cell signaling. The Journal of Biological Chemistry. PMID 32467228 DOI: 10.1074/Jbc.Ra120.013639  0.342
2020 Paredes SD, Kim S, Rooney MT, Greenwood AI, Hristova K, Cotten ML. Enhancing the membrane activity of Piscidin 1 through peptide metallation and the presence of oxidized lipid species: Implications for the unification of host defense mechanisms at lipid membranes. Biochimica Et Biophysica Acta. Biomembranes. 183236. PMID 32126226 DOI: 10.1016/J.Bbamem.2020.183236  0.535
2020 Wu E, Kim SY, Hristova K, Wimley WC. Cytosolic Delivery of Antibodies and Other Macromolecules Biophysical Journal. 118: 384a. DOI: 10.1016/J.Bpj.2019.11.2189  0.498
2020 Vu VH, Light TP, Hristova K, Leckband DE. Structure-function Analysis of E-cadherin Dimerization at the Plasma Membrane Biophysical Journal. 118: 362a. DOI: 10.1016/J.Bpj.2019.11.2083  0.36
2020 Paul MD, Zuo Y, Rainwater R, Gu L, Hristova K. Expanding Number and Brightness to Determine the Oligomer Size of Membrane Proteins in Live Cells as a Function of Concentration Biophysical Journal. 118: 246a. DOI: 10.1016/J.Bpj.2019.11.1442  0.387
2020 Cotten M, Paredes S, Kim S, Greenwood A, Xiong Y, Hristova K, Giles D. Effects of Polyunsaturated Fatty Acids and Metallation on the Antimicrobial Activity and Membrane-Disruptive Properties of Host-Defense Metallopeptide PISCIDIN 1 Biophysical Journal. 118: 237a-238a. DOI: 10.1016/J.Bpj.2019.11.1400  0.356
2019 Wimley WC, Hristova K. The Mechanism of Membrane Permeabilization by Peptides: Still an Enigma. Australian Journal of Chemistry. 73: 96-103. PMID 32341596 DOI: 10.1071/Ch19449  0.72
2019 Paul MD, Hristova K. The transition model of RTK activation: A quantitative framework for understanding RTK signaling and RTK modulator activity. Cytokine & Growth Factor Reviews. PMID 31711797 DOI: 10.1016/J.Cytogfr.2019.10.004  0.309
2019 Gomez-Soler M, Petersen Gehring M, Lechtenberg BC, Zapata-Mercado E, Hristova K, Pasquale EB. Engineering Nanomolar Peptide LigandsThat Differentially Modulate EphA2 Receptor Signaling. The Journal of Biological Chemistry. PMID 31015204 DOI: 10.2210/Pdb6Nkp/Pdb  0.455
2019 Kim SY, Pittman AE, Zapata-Mercado E, King GM, Wimley WC, Hristova K. Mechanism of action of peptides that cause pH-triggered macromolecular poration of lipid bilayers. Journal of the American Chemical Society. PMID 30916949 DOI: 10.1021/Jacs.9B01970  0.71
2019 Pittman A, Kim SY, Wimley WC, Hristova K, King G. Membrane Remodeling Induced by a pH Dependant Pore Forming Peptide via Atomic Force Microscopy Biophysical Journal. 116: 83a-84a. DOI: 10.1016/J.Bpj.2018.11.494  0.663
2019 Komin A, Bogorad MI, Lin R, Cui H, Searson PC, Hristova K. Peptide-Enhanced Cargo Transport across 2D and 3D Epithelial Barriers: A Structure-Function Investigation Biophysical Journal. 116: 513a. DOI: 10.1016/J.Bpj.2018.11.2767  0.328
2019 Rathnayake SS, Hristova K, Johnson ME. Investigating How Membrane Localization Regulates Protein Assembly During Clathrin-Mediated Endocytosis Biophysical Journal. 116: 369a. DOI: 10.1016/J.Bpj.2018.11.2008  0.404
2019 Wirth D, Hristova K, Pasquale E. Investigating the Role of the Transmembrane Helix of EphA2 in Signal Transduction across the Plasma Membrane Biophysical Journal. 116: 233a. DOI: 10.1016/J.Bpj.2018.11.1280  0.387
2018 Paul MD, Hristova K. The RTK Interactome: Overview and Perspective on RTK Heterointeractions. Chemical Reviews. PMID 30589534 DOI: 10.1021/Acs.Chemrev.8B00467  0.338
2018 Li S, Kim SY, Pittman AE, King GM, Wimley WC, Hristova K. Potent macromolecule-sized poration of lipid bilayers by the macrolittins, a synthetically evolved family of pore-forming peptides. Journal of the American Chemical Society. PMID 29694775 DOI: 10.1021/Jacs.8B03026  0.687
2018 Hristova K. Plasma Membrane Models Biophysical Journal. 114: 402a. DOI: 10.1016/J.Bpj.2017.11.2229  0.376
2018 Kim SY, Wimley WC, Hristova K. Mechanism of Action of pH-Triggered, Membrane Active Peptides: Effect of Negative Charge Biophysical Journal. 114: 376a. DOI: 10.1016/J.Bpj.2017.11.2082  0.676
2018 Komin A, Lin R, Cui H, Searson PC, Hristova K. Cell-Penetrating Peptide for Transcellular Transport: The Effect of Physico-Chemical Properties on Permeability Biophysical Journal. 114: 267a. DOI: 10.1016/J.Bpj.2017.11.1546  0.393
2018 Wu E, Wang Y, Hristova K, Wimley W. Using pH Sensitive Peptides for the Endosomal Release of Antibodies Biophysical Journal. 114: 266a. DOI: 10.1016/J.Bpj.2017.11.1541  0.604
2017 Hristova K. Interactions between membrane receptors in cellular membranes. Biochimica Et Biophysica Acta. PMID 28583829 DOI: 10.1016/j.bbamem.2017.05.020  0.349
2017 He J, Melnik LI, Komin A, Wiedman G, Fuselier T, Morris CF, Starr CG, Searson PC, Gallaher WR, Hristova K, Garry RF, Wimley WC. Ebola Virus Delta Peptide is a Viroporin. Journal of Virology. PMID 28539454 DOI: 10.1128/Jvi.00438-17  0.813
2017 King C, Raicu V, Hristova K. Understanding the FRET Signatures of Interacting Membrane Proteins. The Journal of Biological Chemistry. 292: 5291-5310. PMID 28188294 DOI: 10.1016/J.Bpj.2015.11.2310  0.399
2017 Ahmed F, Hristova K. Examining the Effects of Neurotrophin 3 and Nerve Growth Factor on the Interaction of Tropomyosin Receptor Kinase A and C Biophysical Journal. 112: 88a. DOI: 10.1016/J.Bpj.2016.11.519  0.311
2017 Komin A, Paul MD, Luera AM, Searson PC, Hristova K. Cell-Penetrating Peptide for Transcellular Transport: Membrane Binding and Uptake in Live Cells Biophysical Journal. 112: 526a-527a. DOI: 10.1016/J.Bpj.2016.11.2847  0.473
2017 He J, Melnik L, Komin A, Starr CG, Fuselier T, Wiedman G, Morris CF, Wang Y, Hristova K, Gallaher W, Garry RF, Wimley WC. The Delta Peptide of Ebola Virus has Potent Viroporin Activity Biophysical Journal. 112: 185a. DOI: 10.1016/J.Bpj.2016.11.1024  0.7
2016 Wiedman G, Kim SY, Zapata-Mercado E, Wimley WC, Hristova K. PH-Triggered, Macromolecule-Sized Poration of Lipid Bilayers by Synthetically Evolved Peptides. Journal of the American Chemical Society. PMID 28001058 DOI: 10.1021/Jacs.6B11447  0.842
2016 Del Piccolo N, Sarabipour S, Hristova K. A New Method to Study Heterodimerization of Membrane Proteins and its Application to Fibroblast Growth Factor Receptors. The Journal of Biological Chemistry. PMID 27927983 DOI: 10.1074/jbc.M116.755777  0.327
2016 Komin A, Russell LM, Hristova KA, Searson PC. Peptide-based strategies for enhanced cell uptake, transcellular transport, and circulation: Mechanisms and challenges. Advanced Drug Delivery Reviews. PMID 27313077 DOI: 10.1016/j.addr.2016.06.002  0.325
2016 King C, Stoneman M, Raicu V, Hristova K. Fully quantified spectral imaging reveals in vivo membrane protein interactions. Integrative Biology : Quantitative Biosciences From Nano to Macro. 8: 216-29. PMID 26787445 DOI: 10.1039/C5Ib00202H  0.463
2016 Sarabipour S, Hristova K. Mechanism of FGF receptor dimerization and activation. Nature Communications. 7: 10262. PMID 26725515 DOI: 10.1038/Ncomms10262  0.325
2016 King C, Hristova K. In Vivo Studies of VEGFR2 Interactions in the Presence and Absence of VEGF Biophysical Journal. 110: 90a. DOI: 10.1016/J.Bpj.2015.11.542  0.324
2016 Singh DR, Paul M, Hristova K. Does Receptor Phosphorylation Affect Lateral Dimerization? Biophysical Journal. 110: 532a. DOI: 10.1016/J.Bpj.2015.11.2845  0.315
2016 Kim SY, Wiedman G, Li L, Wimley WC, Hristova K. Design of pH Triggered, Macromolecular Pore Forming Peptides for Endosomal Escape Biophysical Journal. 110: 415a. DOI: 10.1016/J.Bpj.2015.11.2242  0.711
2016 Komin A, Lin R, Cui H, Searson PC, Hristova K. Towards the Delivery of Cargo Across Biological Barriers Biophysical Journal. 110: 414a. DOI: 10.1016/J.Bpj.2015.11.2239  0.439
2016 Del Piccolo N, Sarabipour S, Hristova K. Heterodimerization of Wild-Type and Mutant Fibroblast Growth Factor Receptors in Cell-Derived Vesicles Biophysical Journal. 110: 225a. DOI: 10.1016/J.Bpj.2015.11.1244  0.35
2015 Huang W, Besar K, Zhang Y, Yang S, Wiedman G, Liu Y, Guo W, Song J, Hemker K, Hristova K, Kymissis IJ, Katz HE. A High-Capacitance Salt-Free Dielectric for Self-Healable, Printable, and Flexible Organic Field Effect Transistors and Chemical Sensor. Advanced Functional Materials. 25: 3745-3755. PMID 29238288 DOI: 10.1002/Adfm.201404228  0.698
2015 Singh DR, Ahmed F, King C, Gupta N, Salotto M, Pasquale EB, Hristova K. EphA2 unliganded dimers suppress EphA2 pro-tumorigenic signaling. The Journal of Biological Chemistry. PMID 26363067 DOI: 10.1074/Jbc.M115.676866  0.331
2015 Sarabipour S, Del Piccolo N, Hristova K. Characterization of membrane protein interactions in plasma membrane derived vesicles with quantitative imaging Förster resonance energy transfer. Accounts of Chemical Research. 48: 2262-9. PMID 26244699 DOI: 10.1021/Acs.Accounts.5B00238  0.472
2015 Sarabipour S, Chan RB, Zhou B, Di Paolo G, Hristova K. Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation. Biochimica Et Biophysica Acta. 1848: 1591-8. PMID 25896659 DOI: 10.1016/J.Bbamem.2015.04.002  0.442
2015 Sarabipour S, Hristova K. FGFR3 unliganded dimer stabilization by the juxtamembrane domain. Journal of Molecular Biology. 427: 1705-14. PMID 25688803 DOI: 10.1016/J.Jmb.2015.02.013  0.354
2015 Wiedman G, Wimley WC, Hristova K. Testing the limits of rational design by engineering pH sensitivity into membrane-active peptides. Biochimica Et Biophysica Acta. 1848: 951-7. PMID 25572997 DOI: 10.1016/J.Bbamem.2014.12.023  0.831
2015 He L, Hristova K. Quantification of the effects of mutations on receptor tyrosine kinase (RTK) activation in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 1233: 81-7. PMID 25319891 DOI: 10.1007/978-1-4939-1789-1_8  0.505
2015 He J, Wiedman G, Hristova K, Wimley WC. Synthetic Molecular Evolution Approach: Discovery and Characterization of Novel Antiviral Peptides Biophysical Journal. 108: 497a. DOI: 10.1016/J.Bpj.2014.11.2721  0.707
2015 Byrne P, Hristova K, Leahy D. Mechanisms of Autoinhibition and Dimerization of the EGF Receptor Family Biophysical Journal. 108: 351a. DOI: 10.1016/J.Bpj.2014.11.1922  0.399
2015 Singh DR, King C, Gupta NR, Salotto M, Hristova K. Dimerization of EphA2 in Cell Membranes Biophysical Journal. 108: 322a. DOI: 10.1016/J.Bpj.2014.11.1752  0.341
2015 Salotto M, Singh DR, King C, Byrne P, Leahy D, Hristova K. Comparison of EGFR Dimer Stabilities in the Presence and Absence of the Ligand EGF Biophysical Journal. 108: 258a. DOI: 10.1016/J.Bpj.2014.11.1429  0.337
2015 King CR, Hristova K. In vivo Thermodynamics of RTKS in the Cell Membrane: Quantitative Spectral FRET Biophysical Journal. 108: 258a. DOI: 10.1016/J.Bpj.2014.11.1428  0.362
2015 Del Piccolo N, Hristova K. Effect of Thanatophoric Dysplasia Type I Mutations on Fibroblast Growth Factor Receptor 3 Dimerization Biophysical Journal. 108: 256a. DOI: 10.1016/J.Bpj.2014.11.1419  0.317
2014 Wimley WC, Hristova K. Interfacially active peptides and proteins. Preface. Biochimica Et Biophysica Acta. 1838: 2139. PMID 24993833 DOI: 10.1016/J.Bbamem.2014.06.001  0.612
2014 King C, Sarabipour S, Byrne P, Leahy DJ, Hristova K. The FRET signatures of noninteracting proteins in membranes: simulations and experiments. Biophysical Journal. 106: 1309-17. PMID 24655506 DOI: 10.1016/J.Bpj.2014.01.039  0.372
2014 Placone J, He L, Del Piccolo N, Hristova K. Strong dimerization of wild-type ErbB2/Neu transmembrane domain and the oncogenic Val664Glu mutant in mammalian plasma membranes. Biochimica Et Biophysica Acta. 1838: 2326-30. PMID 24631664 DOI: 10.1016/J.Bbamem.2014.03.001  0.663
2014 Wiedman G, Fuselier T, He J, Searson PC, Hristova K, Wimley WC. Highly efficient macromolecule-sized poration of lipid bilayers by a synthetically evolved peptide. Journal of the American Chemical Society. 136: 4724-31. PMID 24588399 DOI: 10.1021/Ja500462S  0.832
2014 Sarabipour S, Hristova K. FGF1 and FGF2 Induced FGFR3 Dimerization in Plasma Membrane Derived Vesicles Biophysical Journal. 106: 103a. DOI: 10.1016/J.Bpj.2013.11.640  0.41
2014 Wiedman G, Fuselier T, He J, Searson P, Hristova K, Wimley WC. A Novel Functional Class of Pore-Forming Peptides Biophysical Journal. 106: 85a-86a. DOI: 10.1016/J.Bpj.2013.11.547  0.717
2014 King CR, Sarabipour S, Byrne P, Leahy D, Hristova K. The FRET Signatures of Non-Interacting Proteins in Cellular Membranes Biophysical Journal. 106: 719a. DOI: 10.1016/J.Bpj.2013.11.3973  0.479
2014 Singh DR, King C, Placone J, Cao Q, Ghosh P, Hristova K. Dimerization of FGFR3 in Living Cells Biophysical Journal. 106: 480a. DOI: 10.1016/J.Bpj.2013.11.2709  0.424
2013 He J, Kauffman WB, Fuselier T, Naveen SK, Voss TG, Hristova K, Wimley WC. Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides. The Journal of Biological Chemistry. 288: 29974-86. PMID 23983125 DOI: 10.1074/Jbc.M113.488312  0.712
2013 Sarabipour S, Hristova K. FGFR3 transmembrane domain interactions persist in the presence of its extracellular domain. Biophysical Journal. 105: 165-71. PMID 23823235 DOI: 10.1016/J.Bpj.2013.05.053  0.407
2013 Cruz J, Mihailescu M, Wiedman G, Herman K, Searson PC, Wimley WC, Hristova K. A membrane-translocating peptide penetrates into bilayers without significant bilayer perturbations. Biophysical Journal. 104: 2419-28. PMID 23746514 DOI: 10.1016/J.Bpj.2013.04.043  0.729
2013 Sarabipour S, Hristova K. Glycophorin A transmembrane domain dimerization in plasma membrane vesicles derived from CHO, HEK 293T, and A431 cells. Biochimica Et Biophysica Acta. 1828: 1829-33. PMID 23562404 DOI: 10.1016/J.Bbamem.2013.03.022  0.463
2013 Wiedman G, Herman K, Searson P, Wimley WC, Hristova K. The electrical response of bilayers to the bee venom toxin melittin: evidence for transient bilayer permeabilization. Biochimica Et Biophysica Acta. 1828: 1357-64. PMID 23384418 DOI: 10.1016/J.Bbamem.2013.01.021  0.84
2013 Wiedman G, Herman K, Searson P, Wimley WC, Hristova K. Electrical Response of Bilayers to the Bee Venom Toxin Melittin Biophysical Journal. 104: 65a. DOI: 10.1016/J.Bpj.2012.11.396  0.679
2013 He J, Fuselier T, Hristova K, Wimley WC. Exploring the Sequence Determinants of Spontaneous Membrane-Translocating Peptides Biophysical Journal. 104: 250a. DOI: 10.1016/J.Bpj.2012.11.1405  0.726
2013 Sarabipour S, Hristova K. GpA Dimerization in Plasma Membranes of CHO, HEK293T and A431 Cells Biophysical Journal. 104: 223a. DOI: 10.1016/J.Bpj.2012.11.1257  0.441
2012 He L, Hristova K. Consequences of replacing EGFR juxtamembrane domain with an unstructured sequence. Scientific Reports. 2: 854. PMID 23152945 DOI: 10.1038/Srep00854  0.563
2012 Placone J, Hristova K. Direct assessment of the effect of the Gly380Arg achondroplasia mutation on FGFR3 dimerization using quantitative imaging FRET. Plos One. 7: e46678. PMID 23056398 DOI: 10.1371/Journal.Pone.0046678  0.311
2012 Del Piccolo N, Placone J, He L, Agudelo SC, Hristova K. Production of plasma membrane vesicles with chloride salts and their utility as a cell membrane mimetic for biophysical characterization of membrane protein interactions. Analytical Chemistry. 84: 8650-5. PMID 22985263 DOI: 10.1021/Ac301776J  0.655
2012 He J, Hristova K, Wimley WC. A highly charged voltage-sensor helix spontaneously translocates across membranes. Angewandte Chemie (International Ed. in English). 51: 7150-3. PMID 22696138 DOI: 10.1002/Anie.201202741  0.606
2012 He L, Serrano C, Niphadkar N, Shobnam N, Hristova K. Effect of the G375C and G346E achondroplasia mutations on FGFR3 activation. Plos One. 7: e34808. PMID 22529939 DOI: 10.1371/Journal.Pone.0034808  0.527
2012 Lin J, Motylinski J, Krauson AJ, Wimley WC, Searson PC, Hristova K. Interactions of membrane active peptides with planar supported bilayers: an impedance spectroscopy study. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 6088-96. PMID 22416892 DOI: 10.1021/La300274N  0.741
2012 Stahl PJ, Cruz JC, Li Y, Michael Yu S, Hristova K. On-the-resin N-terminal modification of long synthetic peptides. Analytical Biochemistry. 424: 137-9. PMID 22387389 DOI: 10.1016/J.Ab.2012.02.032  0.438
2012 Li E, Wimley WC, Hristova K. Transmembrane helix dimerization: beyond the search for sequence motifs. Biochimica Et Biophysica Acta. 1818: 183-93. PMID 21910966 DOI: 10.1016/J.Bbamem.2011.08.031  0.601
2012 He L, Hristova K. Physical-chemical principles underlying RTK activation, and their implications for human disease. Biochimica Et Biophysica Acta. 1818: 995-1005. PMID 21840295 DOI: 10.1016/J.Bbamem.2011.07.044  0.607
2012 Wiedman G, Wimley W, Searson P, Hristova K. Effect of Melittin and Gain-of-Function Melittin Analogs, Discovered by High-Throughput Screening, on Bilayer Properties: An Electrical Impedance Spectroscopy Study Biophysical Journal. 102: 91a. DOI: 10.1016/J.Bpj.2011.11.517  0.68
2012 Wimley WC, Hristova K. The Isolated S4 Voltage Sensor Helix Translocates Spontaneously Across Membranes Biophysical Journal. 102: 615a. DOI: 10.1016/J.Bpj.2011.11.3354  0.695
2012 Hristova K. Platforms for Characterization of Membrane Protein Interactions Biophysical Journal. 102: 439a. DOI: 10.1016/J.Bpj.2011.11.2405  0.493
2011 He L, Hoffmann AR, Serrano C, Hristova K, Wimley WC. High-throughput selection of transmembrane sequences that enhance receptor tyrosine kinase activation. Journal of Molecular Biology. 412: 43-54. PMID 21767549 DOI: 10.1016/J.Jmb.2011.07.004  0.726
2011 Sánchez-Martín MJ, Hristova K, Pujol M, Gómara MJ, Haro I, Alsina MA, Busquets MA. Analysis of HIV-1 fusion peptide inhibition by synthetic peptides from E1 protein of GB virus C. Journal of Colloid and Interface Science. 360: 124-31. PMID 21565353 DOI: 10.1016/J.Jcis.2011.04.053  0.399
2011 Marks JR, Placone J, Hristova K, Wimley WC. Spontaneous membrane-translocating peptides by orthogonal high-throughput screening. Journal of the American Chemical Society. 133: 8995-9004. PMID 21545169 DOI: 10.1021/Ja2017416  0.725
2011 Chen F, Degnin C, Laederich M, Horton WA, Hristova K. The A391E mutation enhances FGFR3 activation in the absence of ligand. Biochimica Et Biophysica Acta. 1808: 2045-50. PMID 21536014 DOI: 10.1016/J.Bbamem.2011.04.007  0.336
2011 He L, Shobnam N, Wimley WC, Hristova K. FGFR3 heterodimerization in achondroplasia, the most common form of human dwarfism. The Journal of Biological Chemistry. 286: 13272-81. PMID 21324899 DOI: 10.1074/Jbc.M110.205583  0.691
2011 Wimley WC, Hristova K. Antimicrobial peptides: successes, challenges and unanswered questions. The Journal of Membrane Biology. 239: 27-34. PMID 21225255 DOI: 10.1007/S00232-011-9343-0  0.64
2011 Hristova K, Wimley WC. A look at arginine in membranes. The Journal of Membrane Biology. 239: 49-56. PMID 21107547 DOI: 10.1007/S00232-010-9323-9  0.616
2011 He L, Shobnam N, Hristova K. Specific inhibition of a pathogenic receptor tyrosine kinase by its transmembrane domain. Biochimica Et Biophysica Acta. 1808: 253-9. PMID 20713021 DOI: 10.1016/J.Bbamem.2010.08.007  0.581
2011 Placone J, Hristova K. Probing Skeletal Dysplasias Caused by Mutations of FGFR3 Using Qi-FRET Biophysical Journal. 100: 547a. DOI: 10.1016/J.Bpj.2010.12.3189  0.367
2011 Sarabipour S, Li E, Hristova K. Effect of FGFR3 Juxtamembrane Domain on FGFR3 Dimerization Biophysical Journal. 100: 546a. DOI: 10.1016/J.Bpj.2010.12.3184  0.383
2011 Marks JR, Hristova K, Wimley WC. Peptides with Multiple Arginines can Spontaneously Translocate across Lipid Vesicle Membranes and across Living Cell Membranes Biophysical Journal. 100: 494a. DOI: 10.1016/J.Bpj.2010.12.2896  0.725
2011 Serrano CM, He L, Hoffman A, Wimley WC, Hristova KA. The Homodimerization Propensities of Transmembrane Helices Selected from a Combinatorial Library Characterized using In Vivo Phosphorylation and Dimerization Assays Biophysical Journal. 100: 419a. DOI: 10.1016/J.Bpj.2010.12.2482  0.713
2011 He L, Agudelo SC, Hristova K. Role of EGFR Juxtamembrane Domain in EGFR Activation Biophysical Journal. 100: 418a. DOI: 10.1016/J.Bpj.2010.12.2478  0.562
2011 Chen L, Hristova K. Characterization of Lipid Asymmetry in Plasma Membrane-Derived Vesicles Biophysical Journal. 100: 338a. DOI: 10.1016/J.Bpj.2010.12.2048  0.64
2011 Cruz JC, Mihailescu M, Wimley W, Hristova K. Studies of Membrane-Active Peptides Using Neutron Diffraction Biophysical Journal. 100: 334a. DOI: 10.1016/J.Bpj.2010.12.2029  0.692
2010 Chen L, Placone J, Novicky L, Hristova K. The extracellular domain of fibroblast growth factor receptor 3 inhibits ligand-independent dimerization. Science Signaling. 3: ra86. PMID 21119106 DOI: 10.1126/Scisignal.2001195  0.568
2010 Schick S, Chen L, Li E, Lin J, Köper I, Hristova K. Assembly of the m2 tetramer is strongly modulated by lipid chain length. Biophysical Journal. 99: 1810-7. PMID 20858425 DOI: 10.1016/J.Bpj.2010.07.026  0.604
2010 He L, Horton W, Hristova K. Physical basis behind achondroplasia, the most common form of human dwarfism. The Journal of Biological Chemistry. 285: 30103-14. PMID 20624921 DOI: 10.1074/Jbc.M109.094086  0.523
2010 Lin J, Szymanski J, Searson PC, Hristova K. Electrically addressable, biologically relevant surface-supported bilayers. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 12054-9. PMID 20446710 DOI: 10.1021/La101084B  0.479
2010 Lin J, Szymanski J, Searson PC, Hristova K. Effect of a polymer cushion on the electrical properties and stability of surface-supported lipid bilayers. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 3544-8. PMID 20175577 DOI: 10.1021/La903232B  0.469
2010 Chen L, Novicky L, Merzlyakov M, Hristov T, Hristova K. Measuring the energetics of membrane protein dimerization in mammalian membranes. Journal of the American Chemical Society. 132: 3628-35. PMID 20158179 DOI: 10.1021/Ja910692U  0.642
2010 Marks JR, Krauson AJ, Hristova KA, Wimley W. Membrane-Active Peptides: Stable Pore-Forming or Cell-Penetrating Peptides Selected With Orthogonal High-Throughput Screening Biophysical Journal. 98: 85a. DOI: 10.1016/J.Bpj.2009.12.483  0.694
2010 Lin J, Szymanski J, Searson PC, Hristova K. Design of a Biologically Relevant Supported Bilayer Platform for the Study of Membrane Active Peptides Biophysical Journal. 98: 285a. DOI: 10.1016/J.Bpj.2009.12.1554  0.55
2010 He L, Hristova K. The Physical Basis Behind Achondroplasia, the Most Common Form of Human Dwarfism Biophysical Journal. 98: 246. DOI: 10.1016/J.Bpj.2009.12.1336  0.591
2010 Sarabipour S, Hristova K. Quantitative Measurements of Receptor Interactions in Mammalian Cells: Implications for Human Pathologies Biophysical Journal. 98: 245a-246a. DOI: 10.1016/J.Bpj.2009.12.1335  0.424
2010 Chen L, Novicky LJ, Merzlyakov M, Hristova K. Energetics of Glycophorin A Dimerization in Mammalian Plasma Membranes Biophysical Journal. 98: 224a. DOI: 10.1016/J.Bpj.2009.12.1211  0.648
2009 Snider C, Jayasinghe S, Hristova K, White SH. MPEx: a tool for exploring membrane proteins. Protein Science : a Publication of the Protein Society. 18: 2624-8. PMID 19785006 DOI: 10.1002/Pro.256  0.641
2009 Chen L, Merzlyakov M, Cohen T, Shai Y, Hristova K. Energetics of ErbB1 transmembrane domain dimerization in lipid bilayers. Biophysical Journal. 96: 4622-30. PMID 19486684 DOI: 10.1016/J.Bpj.2009.03.004  0.555
2009 O'Connor S, Li E, Majors BS, He L, Placone J, Baycin D, Betenbaugh MJ, Hristova K. Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressing the anti-apoptotic gene Bcl-xL. Protein Expression and Purification. 67: 41-7. PMID 19376231 DOI: 10.1016/J.Pep.2009.04.007  0.601
2009 Li E, Merzlyakov M, Lin J, Searson P, Hristova K. Utility of surface-supported bilayers in studies of transmembrane helix dimerization. Journal of Structural Biology. 168: 53-60. PMID 19303932 DOI: 10.1016/J.Jsb.2009.03.005  0.362
2009 Walkenhorst WF, Merzlyakov M, Hristova K, Wimley WC. Polar residues in transmembrane helices can decrease electrophoretic mobility in polyacrylamide gels without causing helix dimerization. Biochimica Et Biophysica Acta. 1788: 1321-31. PMID 19265670 DOI: 10.1016/J.Bbamem.2009.02.017  0.689
2009 Han X, Hristova K. Viewing the bilayer hydrocarbon core using neutron diffraction. The Journal of Membrane Biology. 227: 123-31. PMID 19169614 DOI: 10.1007/s00232-008-9151-3  0.345
2009 Wimley WC, Hristova K, Merzliakov M. Polar Residues in Transmembrane Helices can Dramatically Reduce Mobility on SDS Gels WITHOUT Dimerization Biophysical Journal. 96: 548a. DOI: 10.1016/J.Bpj.2008.12.2971  0.672
2009 Hagerty N, Li E, Hristova K. Integration of Plasma Membrane in Supported Lipid Bilayers Biophysical Journal. 96: 329a. DOI: 10.1016/J.Bpj.2008.12.1656  0.471
2009 He L, Shobnam N, O'Connor SK, Hristova K. Effect of Short Transmembrane Peptides on the Activation and Dimerization of an FGFR3 Pathogenic Mutant Biophysical Journal. 96: 328a. DOI: 10.1016/J.Bpj.2008.12.1648  0.632
2009 Hristova K. New Tools For Studies Of Membrane Protein Dimerization In Mammalian Membranes Biophysical Journal. 96: 1a. DOI: 10.1016/J.Bpj.2008.12.006  0.462
2008 Merzlyakov M, Li E, Hristova K. Surface supported bilayer platform for studies of lateral association of proteins in membranes (Mini Review). Biointerphases. 3: FA80. PMID 20408673 DOI: 10.1116/1.2912096  0.409
2008 Lin J, Merzlyakov M, Hristova K, Searson PC. Impedance spectroscopy of bilayer membranes on single crystal silicon. Biointerphases. 3: FA33. PMID 20408667 DOI: 10.1116/1.2896117  0.431
2008 Merzlyakov M, Hristova K. Forster resonance energy transfer measurements of transmembrane helix dimerization energetics. Methods in Enzymology. 450: 107-27. PMID 19152858 DOI: 10.1016/S0076-6879(08)03406-X  0.485
2008 He L, Hristova K. Pathogenic activation of receptor tyrosine kinases in mammalian membranes. Journal of Molecular Biology. 384: 1130-42. PMID 18976668 DOI: 10.1016/J.Jmb.2008.10.036  0.54
2008 Chang WK, Wimley WC, Searson PC, Hristova K, Merzlyakov M. Characterization of antimicrobial peptide activity by electrochemical impedance spectroscopy. Biochimica Et Biophysica Acta. 1778: 2430-6. PMID 18657512 DOI: 10.1016/J.Bbamem.2008.06.016  0.701
2008 Han X, Hristova K, Wimley WC. Protein folding in membranes: insights from neutron diffraction studies of a membrane beta-sheet oligomer. Biophysical Journal. 94: 492-505. PMID 17872952 DOI: 10.1529/Biophysj.107.113183  0.673
2007 Nikolov V, Lin J, Merzlyakov M, Hristova K, Searson PC. Electrical measurements of bilayer membranes formed by Langmuir-Blodgett deposition on single-crystal silicon. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 13040-5. PMID 18004893 DOI: 10.1021/La702147M  0.321
2007 Merzlyakov M, Chen L, Hristova K. Studies of receptor tyrosine kinase transmembrane domain interactions: the EmEx-FRET method. The Journal of Membrane Biology. 215: 93-103. PMID 17565424 DOI: 10.1007/S00232-007-9009-0  0.596
2006 Nikolov V, Radisic A, Hristova K, Searson PC. Bias-dependent admittance in hybrid bilayer membranes. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 7156-8. PMID 16893210 DOI: 10.1021/La061562K  0.321
2006 Merzlyakov M, You M, Li E, Hristova K. Transmembrane helix heterodimerization in lipid bilayers: probing the energetics behind autosomal dominant growth disorders. Journal of Molecular Biology. 358: 1-7. PMID 16500676 DOI: 10.1016/J.Jmb.2006.01.086  0.337
2006 Merzlyakov M, Li E, Hristova K. Directed assembly of surface-supported bilayers with transmembrane helices. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 1247-53. PMID 16430290 DOI: 10.1021/la051933h  0.407
2006 Li E, You M, Hristova K. FGFR3 dimer stabilization due to a single amino acid pathogenic mutation. Journal of Molecular Biology. 356: 600-12. PMID 16384584 DOI: 10.1016/J.Jmb.2005.11.077  0.347
2006 Hristova K. Lipid Rafts and Caveolae: From Membrane Biophysics to Cell Biology. Edited by Christopher J. Fielding. Chembiochem. 7: 1279-1280. DOI: 10.1002/Cbic.200600238  0.417
2005 Hristova K, White SH. An experiment-based algorithm for predicting the partitioning of unfolded peptides into phosphatidylcholine bilayer interfaces. Biochemistry. 44: 12614-9. PMID 16156674 DOI: 10.1021/Bi051193B  0.614
2005 You M, Li E, Wimley WC, Hristova K. Forster resonance energy transfer in liposomes: measurements of transmembrane helix dimerization in the native bilayer environment. Analytical Biochemistry. 340: 154-64. PMID 15802141 DOI: 10.1016/J.Ab.2005.01.035  0.657
2005 Iwamoto T, You M, Li E, Spangler J, Tomich JM, Hristova K. Synthesis and initial characterization of FGFR3 transmembrane domain: consequences of sequence modifications. Biochimica Et Biophysica Acta. 1668: 240-7. PMID 15737335 DOI: 10.1016/J.Bbamem.2004.12.012  0.479
2005 Li E, You M, Hristova K. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and forster resonance energy transfer suggest weak interactions between fibroblast growth factor receptor 3 (FGFR3) transmembrane domains in the absence of extracellular domains and ligands. Biochemistry. 44: 352-60. PMID 15628877 DOI: 10.1021/Bi048480K  0.497
2001 Jayasinghe S, Hristova K, White SH. Energetics, stability, and prediction of transmembrane helices. Journal of Molecular Biology. 312: 927-34. PMID 11580239 DOI: 10.1006/Jmbi.2001.5008  0.56
2001 White SH, Ladokhin AS, Jayasinghe S, Hristova K. How membranes shape protein structure. The Journal of Biological Chemistry. 276: 32395-8. PMID 11432876 DOI: 10.1074/Jbc.R100008200  0.538
2001 Jayasinghe S, Hristova K, White SH. MPtopo: A database of membrane protein topology. Protein Science : a Publication of the Protein Society. 10: 455-8. PMID 11266632 DOI: 10.1110/Ps.43501  0.497
2001 Hristova K, Dempsey CE, White SH. Structure, location, and lipid perturbations of melittin at the membrane interface. Biophysical Journal. 80: 801-11. PMID 11159447 DOI: 10.1016/S0006-3495(01)76059-6  0.656
2001 Dempsey CE, Sessions RB, Hristova K, White SH. Disulphide-dimerised analogues of melittin and magainin: Pore kinetics and molecular dynamics simulations in membranes Biochemical Society Transactions. 29: A74-A74. DOI: 10.1042/Bst029A074  0.57
1999 Hristova K, Wimley WC, Mishra VK, Anantharamiah GM, Segrest JP, White SH. An amphipathic α-helix at a membrane interface: A structural study using a novel X-ray diffraction method Journal of Molecular Biology. 290: 99-117. PMID 10388560 DOI: 10.1006/Jmbi.1999.2840  0.738
1998 White SH, Wimley WC, Ladokhin AS, Hristova K. Protein folding in membranes: Determining energetics of peptide-bilayer interactions Methods in Enzymology. 295: 62-87. PMID 9750214 DOI: 10.1016/S0076-6879(98)95035-2  0.773
1998 Hristova K, White SH. Determination of the hydrocarbon core structure of fluid dioleoylphosphocholine (DOPC) bilayers by x-ray diffraction using specific bromination of the double-bonds: effect of hydration. Biophysical Journal. 74: 2419-33. PMID 9591668 DOI: 10.1016/S0006-3495(98)77950-0  0.528
1998 Wimley WC, Hristova K, Ladokhin AS, Silvestro L, Axelsen PH, White SH. Folding of β-sheet membrane proteins: A hydrophobic hexapeptide model Journal of Molecular Biology. 277: 1091-1110. PMID 9571025 DOI: 10.1006/Jmbi.1998.1640  0.759
1997 Hristova K, Selsted ME, White SH. Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins Journal of Biological Chemistry. 272: 24224-24233. PMID 9305875 DOI: 10.1074/Jbc.272.39.24224  0.578
1997 Ladokhin AS, Wimley WC, Hristova K, White SH. Mechanism of leakage of contents of membrane vesicles determined by fluorescence requenching Methods in Enzymology. 278: 474-487. PMID 9170328 DOI: 10.1016/S0076-6879(97)78025-X  0.679
1996 Hristova K, Selsted ME, White SH. Interactions of monomeric rabbit neutrophil defensins with bilayers: Comparison with dimeric human defensin HNP-2 Biochemistry. 35: 11888-11894. PMID 8794771 DOI: 10.1021/Bi961100D  0.49
1995 Kenworthy AK, Hristova K, Needham D, McIntosh TJ. Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol). Biophysical Journal. 68: 1921-36. PMID 7612834 DOI: 10.1016/S0006-3495(95)80369-3  0.535
1995 Hristova K, Needham D. Influence of bilayer fluctuations on the steric interactions between polymer-grafted bilayers Liquid Crystals. 18: 423-430. DOI: 10.1080/02678299508036641  0.527
1995 Hristova K, Kenworthy A, McIntosh TJ. Effect of Bilayer Composition on the Phase Behavior of Liposomal Suspensions Containing Poly(ethylene glycol)-Lipids Macromolecules. 28: 7693-7699. DOI: 10.1021/Ma00127A015  0.36
1995 Hristova K, Needham D. Phase Behavior of a Lipid/Polymer-Lipid Mixture in Aqueous Medium Macromolecules. 28: 991-1002. DOI: 10.1021/Ma00108A029  0.474
1993 Petrov AG, Miller BA, Hristova K, Usherwood PN. Flexoelectric effects in model and native membranes containing ion channels. European Biophysics Journal : Ebj. 22: 289-300. PMID 8253055 DOI: 10.1007/Bf00180263  0.411
1992 Needham D, Hristova K, McIntosh TJ, Dewhirst M, Wu N, Lasic DD. Polymer-Grafted Liposomes: Physical Basis for the “Stealth” Property Journal of Liposome Research. 2: 411-430. DOI: 10.3109/08982109209010218  0.465
1992 Hristova K, Bivas I, Derzhanski A. Frequency Dependence of the Membrane Flexoelectric Voltage Response. Adsorption of Multivalent Counterions on the Surface of Curved Lipid Bilayer Molecular Crystals and Liquid Crystals Science and Technology. Section a. Molecular Crystals and Liquid Crystals. 215: 237-244. DOI: 10.1080/10587259208038530  0.385
1991 Bivas I, Hristova K. The electric part of the curvature elasticity of a membrane and its relation to flexoelectricity Liquid Crystals. 9: 883-892. DOI: 10.1080/02678299108055010  0.427
1991 Hristova K, Bivas I, Petrov AG, Derzhanski A. Influence of the Electric Double Layers of the Membrane on the Value of its Flexoelectric Coefficient Molecular Crystals and Liquid Crystals. 200: 71-77. DOI: 10.1080/00268949108044232  0.374
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