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Michelle M. Le Beau - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Cancer cytogenetics and genetics
Website:
http://t-aml.uchicago.edu/scientific-leadership/michelle-le-beau/

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cahill KE, Karimi YH, Karrison TG, Jain N, Green M, Weiner H, Fulton N, Kadri S, Godley LA, Artz AS, Liu H, Thirman MJ, Le Beau MM, McNerney ME, Segal J, et al. A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia. Blood Advances. 4: 599-606. PMID 32074275 DOI: 10.1182/bloodadvances.2019000795  0.4
2018 Cheng JX, Chen L, Li Y, Cloe A, Yue M, Wei J, Watanabe KA, Shammo JM, Anastasi J, Shen QJ, Larson RA, He C, Le Beau MM, Vardiman JW. Author Correction: RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nature Communications. 9: 2286. PMID 29875356 DOI: 10.1038/s41467-018-04518-9  0.4
2018 Li Z, Huang H, Chen P, He M, Li Y, Arnovitz S, Jiang X, He C, Hyjek E, Zhang J, Zhang Z, Elkahloun A, Cao D, Shen C, Wunderlich M, ... ... Le Beau MM, et al. Publisher Correction: miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Nature Communications. 9: 16192. PMID 29633759 DOI: 10.1038/ncomms16192  0.4
2018 Cheng JX, Chen L, Li Y, Cloe A, Yue M, Wei J, Watanabe KA, Shammo JM, Anastasi J, Shen QJ, Larson RA, He C, Le Beau MM, Vardiman JW. RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nature Communications. 9: 1163. PMID 29563491 DOI: 10.1038/s41467-018-03513-4  0.4
2017 McNerney ME, Godley LA, Le Beau MM. Therapy-related myeloid neoplasms: when genetics and environment collide. Nature Reviews. Cancer. 17: 513-527. PMID 28835720 DOI: 10.1038/nrc.2017.60  0.4
2016 Jiang X, Bugno J, Hu C, Yang Y, Herold T, Qi J, Chen P, Gurbuxani S, Arnovitz S, Strong J, Ferchen K, Ulrich B, Weng H, Wang Y, Huang H, ... ... Le Beau MM, et al. Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles. Cancer Research. PMID 27280396 DOI: 10.1158/0008-5472.CAN-15-2949  0.4
2016 Jiang X, Hu C, Arnovitz S, Bugno J, Yu M, Zuo Z, Chen P, Huang H, Ulrich B, Gurbuxani S, Weng H, Strong J, Wang Y, Li Y, Salat J, ... ... Le Beau MM, et al. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia. Nature Communications. 7: 11452. PMID 27116251 DOI: 10.1038/ncomms11452  0.4
2016 Stoddart A, Qian Z, Fernald AA, Bergerson RJ, Wang J, Karrison T, Anastasi J, Bartom ET, Sarver AL, McNerney ME, Largaespada DA, Le Beau MM. Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms. Haematologica. PMID 26944478 DOI: 10.3324/haematol.2015.139527  0.52
2015 Churpek JE, Marquez R, Neistadt B, Claussen K, Lee MK, Churpek MM, Huo D, Weiner H, Bannerjee M, Godley LA, Le Beau MM, Pritchard CC, Walsh T, King MC, Olopade OI, et al. Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia. Cancer. PMID 26641009 DOI: 10.1002/cncr.29615  0.4
2015 Sundaravel S, Duggan R, Bhagat T, Ebenezer DL, Liu H, Yu Y, Bartenstein M, Unnikrishnan M, Karmakar S, Liu TC, Torregroza I, Quenon T, Anastasi J, McGraw KL, Pellagatti A, ... ... Le Beau MM, et al. Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes. Proceedings of the National Academy of Sciences of the United States of America. 112: E6359-E6368. PMID 26578796 DOI: 10.1073/pnas.1516394112  0.36
2015 Stoddart A, Nakitandwe J, Chen SC, Downing JR, Le Beau MM. Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms. Blood. PMID 26567158 DOI: 10.1182/blood-2015-10-673228  0.36
2015 Li Z, Chen P, Su R, Li Y, Hu C, Wang Y, Arnovitz S, He M, Gurbuxani S, Zuo Z, Elkahloun AG, Li S, Weng H, Huang H, Neilly MB, ... ... Le Beau MM, et al. Overexpression and knockout of miR-126 both promote leukemogenesis through targeting distinct gene signaling. Blood. PMID 26361793 DOI: 10.1182/blood-2015-04-639062  0.36
2015 Amabile G, Di Ruscio A, Müller F, Welner RS, Yang H, Ebralidze AK, Zhang H, Levantini E, Qi L, Martinelli G, Brummelkamp T, Le Beau MM, Figueroa ME, Bock C, Tenen DG. Dissecting the role of aberrant DNA methylation in human leukaemia. Nature Communications. 6: 7091. PMID 25997600 DOI: 10.1038/ncomms8091  0.52
2015 Zhao Z, Chen CC, Rillahan CD, Shen R, Kitzing T, McNerney ME, Diaz-Flores E, Zuber J, Shannon K, Le Beau MM, Spector MS, Kogan SC, Lowe SW. Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. Nature Genetics. 47: 539-43. PMID 25822087 DOI: 10.1038/ng.3251  0.52
2014 Wood AM, Rendtlew Danielsen JM, Lucas CA, Rice EL, Scalzo D, Shimi T, Goldman RD, Smith ED, Le Beau MM, Kosak ST. TRF2 and lamin A/C interact to facilitate the functional organization of chromosome ends. Nature Communications. 5: 5467. PMID 25399868 DOI: 10.1038/ncomms6467  0.52
2014 McNerney ME, Brown CD, Peterson AL, Banerjee M, Larson RA, Anastasi J, Le Beau MM, White KP. The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q). British Journal of Haematology. 166: 550-6. PMID 24931631 DOI: 10.1111/bjh.12964  0.52
2014 Young DJ, Stoddart A, Nakitandwe J, Chen SC, Qian Z, Downing JR, Le Beau MM. Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts. Haematologica. 99: 1032-40. PMID 24532040 DOI: 10.3324/haematol.2013.098657  0.52
2014 Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, et al. β-Catenin induces T-cell transformation by promoting genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 111: 391-6. PMID 24371308 DOI: 10.1073/pnas.1315752111  0.52
2014 Stoddart A, Wang J, Fernald AA, Karrison T, Anastasi J, Le Beau MM. Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc. Blood. 123: 228-38. PMID 24264229 DOI: 10.1182/blood-2013-05-506568  0.52
2013 Chen P, Price C, Li Z, Li Y, Cao D, Wiley A, He C, Gurbuxani S, Kunjamma RB, Huang H, Jiang X, Arnovitz S, Xu M, Hong GM, Elkahloun AG, ... ... Le Beau MM, et al. miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 11511-6. PMID 23798388 DOI: 10.1073/pnas.1310144110  0.52
2013 Xu J, Haigis KM, Firestone AJ, McNerney ME, Li Q, Davis E, Chen SC, Nakitandwe J, Downing J, Jacks T, Le Beau MM, Shannon K. Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation. Cancer Discovery. 3: 993-1001. PMID 23733505 DOI: 10.1158/2159-8290.CD-13-0096  0.36
2013 Li Z, Herold T, He C, Valk PJ, Chen P, Jurinovic V, Mansmann U, Radmacher MD, Maharry KS, Sun M, Yang X, Huang H, Jiang X, Sauerland MC, Büchner T, ... ... Le Beau MM, et al. Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 1172-81. PMID 23382473 DOI: 10.1200/JCO.2012.44.3184  0.52
2013 Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Davis EM, Link PA, Anastasi J, Le Beau MM, Karpf AR, Godley LA. Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis. Blood. 121: 2059-63. PMID 23315164 DOI: 10.1182/blood-2012-04-421065  0.52
2013 Omidvar N, Maunakea ML, Jones L, Sevcikova S, Yin B, Himmel KL, Tennant TR, Le Beau MM, Largaespada DA, Kogan SC. PML-RARα co-operates with Sox4 in acute myeloid leukemia development in mice. Haematologica. 98: 424-7. PMID 23144197 DOI: 10.3324/haematol.2011.057067  0.52
2012 Crispino JD, Le Beau MM. BMP meets AML: induction of BMP signaling by a novel fusion gene promotes pediatric acute leukemia. Cancer Cell. 22: 567-8. PMID 23153530 DOI: 10.1016/j.ccr.2012.10.008  0.52
2012 Jiang X, Huang H, Li Z, He C, Li Y, Chen P, Gurbuxani S, Arnovitz S, Hong GM, Price C, Ren H, Kunjamma RB, Neilly MB, Salat J, Wunderlich M, ... ... Le Beau MM, et al. MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 109: 19397-402. PMID 23132946 DOI: 10.1073/pnas.1217519109  0.52
2012 Jiang X, Huang H, Li Z, Li Y, Wang X, Gurbuxani S, Chen P, He C, You D, Zhang S, Wang J, Arnovitz S, Elkahloun A, Price C, Hong GM, ... ... Le Beau MM, et al. Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell. 22: 524-35. PMID 23079661 DOI: 10.1016/j.ccr.2012.08.028  0.52
2012 Greenberg PL, Tuechler H, Schanz J, Sanz G, Garcia-Manero G, Solé F, Bennett JM, Bowen D, Fenaux P, Dreyfus F, Kantarjian H, Kuendgen A, Levis A, Malcovati L, Cazzola M, ... ... Le Beau MM, et al. Revised international prognostic scoring system for myelodysplastic syndromes. Blood. 120: 2454-65. PMID 22740453 DOI: 10.1182/blood-2012-03-420489  0.52
2012 Ming M, Wang S, Wu W, Senyuk V, Le Beau MM, Nucifora G, Qian Z. Activation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cells. The Journal of Biological Chemistry. 287: 22683-90. PMID 22589536 DOI: 10.1074/jbc.M112.342089  0.4
2012 Godley LA, Le Beau MM. The histone code and treatments for acute myeloid leukemia. The New England Journal of Medicine. 366: 960-1. PMID 22397660 DOI: 10.1056/NEJMcibr1113401  0.4
2012 Li Z, Huang H, Chen P, He M, Li Y, Arnovitz S, Jiang X, He C, Hyjek E, Zhang J, Zhang Z, Elkahloun A, Cao D, Shen C, Wunderlich M, ... ... Le Beau MM, et al. miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Nature Communications. 3: 688. PMID 22353710 DOI: 10.1038/ncomms1681  0.52
2012 Schanz J, Tüchler H, Solé F, Mallo M, Luño E, Cervera J, Granada I, Hildebrandt B, Slovak ML, Ohyashiki K, Steidl C, Fonatsch C, Pfeilstöcker M, Nösslinger T, Valent P, ... ... Le Beau MM, et al. New comprehensive cytogenetic scoring system for primary myelodysplastic syndromes (MDS) and oligoblastic acute myeloid leukemia after MDS derived from an international database merge. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 820-9. PMID 22331955 DOI: 10.1200/JCO.2011.35.6394  0.52
2012 Li Z, Huang H, Li Y, Jiang X, Chen P, Arnovitz S, Radmacher MD, Maharry K, Elkahloun A, Yang X, He C, He M, Zhang Z, Dohner K, Neilly MB, ... ... Le Beau MM, et al. Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. Blood. 119: 2314-24. PMID 22251480 DOI: 10.1182/blood-2011-10-386235  0.52
2012 Stoddart A, Tennant TR, Fernald AA, Anastasi J, Brodsky FM, Le Beau MM. The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice. Oncogene. 31: 494-506. PMID 21706055 DOI: 10.1038/onc.2011.251  0.52
2011 Odenike O, Anastasi J, Le Beau MM. Myelodysplastic syndromes. Clinics in Laboratory Medicine. 31: 763-84. PMID 22118747 DOI: 10.1016/j.cll.2011.08.005  0.52
2011 Larson RA, Le Beau MM. Prognosis and therapy when acute promyelocytic leukemia and other "good risk" acute myeloid leukemias occur as a therapy-related myeloid neoplasm. Mediterranean Journal of Hematology and Infectious Diseases. 3: e2011032. PMID 21869918 DOI: 10.4084/MJHID.2011.032  0.52
2011 Stoddart A, McNerney ME, Bartom E, Bergerson R, Young DJ, Qian Z, Wang J, Fernald AA, Davis EM, Larson RA, White KP, Le Beau MM. Genetic pathways leading to therapy-related myeloid neoplasms. Mediterranean Journal of Hematology and Infectious Diseases. 3: e2011019. PMID 21713073 DOI: 10.4084/MJHID.2011.019  0.52
2011 Link DC, Schuettpelz LG, Shen D, Wang J, Walter MJ, Kulkarni S, Payton JE, Ivanovich J, Goodfellow PJ, Le Beau M, Koboldt DC, Dooling DJ, Fulton RS, Bender RH, Fulton LL, et al. Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. Jama. 305: 1568-76. PMID 21505135 DOI: 10.1001/jama.2011.473  0.52
2011 Godley LA, Cunningham J, Dolan ME, Huang RS, Gurbuxani S, McNerney ME, Larson RA, Leong H, Lussier Y, Onel K, Odenike O, Stock W, White KP, Le Beau MM. An integrated genomic approach to the assessment and treatment of acute myeloid leukemia. Seminars in Oncology. 38: 215-24. PMID 21421111 DOI: 10.1053/j.seminoncol.2011.01.003  0.52
2011 Lubelsky Y, Sasaki T, Kuipers MA, Lucas I, Le Beau MM, Carignon S, Debatisse M, Prinz JA, Dennis JH, Gilbert DM. Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone. Nucleic Acids Research. 39: 3141-55. PMID 21148149 DOI: 10.1093/nar/gkq1276  0.52
2010 Jones L, Wei G, Sevcikova S, Phan V, Jain S, Shieh A, Wong JC, Li M, Dubansky J, Maunakea ML, Ochoa R, Zhu G, Tennant TR, Shannon KM, Lowe SW, ... Le Beau MM, et al. Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia. The Journal of Experimental Medicine. 207: 2581-94. PMID 21059853 DOI: 10.1084/jem.20091071  0.52
2010 Shah MY, Vasanthakumar A, Barnes NY, Figueroa ME, Kamp A, Hendrick C, Ostler KR, Davis EM, Lin S, Anastasi J, Le Beau MM, Moskowitz IP, Melnick A, Pytel P, Godley LA. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Research. 70: 5840-50. PMID 20587527 DOI: 10.1158/0008-5472.CAN-10-0847  0.52
2010 Godley LA, Njiaju UO, Green M, Weiner H, Lin S, Odenike O, Rich ES, Artz A, Van Besien K, Daugherty CK, Zhang Y, Le Beau MM, Stock W, Larson RA. Treatment of therapy-related myeloid neoplasms with high-dose cytarabine/mitoxantrone followed by hematopoietic stem cell transplant. Leukemia & Lymphoma. 51: 995-1006. PMID 20536346 DOI: 10.3109/10428191003763468  0.4
2010 Wong JC, Zhang Y, Lieuw KH, Tran MT, Forgo E, Weinfurtner K, Alzamora P, Kogan SC, Akagi K, Wolff L, Le Beau MM, Killeen N, Shannon K. Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies. Blood. 115: 4524-32. PMID 20233966 DOI: 10.1182/blood-2009-07-232504  0.52
2010 Qian Z, Joslin JM, Tennant TR, Reshmi SC, Young DJ, Stoddart A, Larson RA, Le Beau MM. Cytogenetic and genetic pathways in therapy-related acute myeloid leukemia. Chemico-Biological Interactions. 184: 50-7. PMID 19958752 DOI: 10.1016/j.cbi.2009.11.025  0.52
2010 Palakodeti A, Lucas I, Jiang Y, Young DJ, Fernald AA, Karrison T, Le Beau MM. Impaired replication dynamics at the FRA3B common fragile site. Human Molecular Genetics. 19: 99-110. PMID 19815620 DOI: 10.1093/hmg/ddp470  0.52
2009 Jiang Y, Lucas I, Young DJ, Davis EM, Karrison T, Rest JS, Le Beau MM. Common fragile sites are characterized by histone hypoacetylation. Human Molecular Genetics. 18: 4501-12. PMID 19717471 DOI: 10.1093/hmg/ddp410  0.52
2009 Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J, Wadleigh M, Malinge S, Yao J, Kilpivaara O, Bhat R, Huberman K, Thomas S, Dolgalev I, Heguy A, Paietta E, ... Le Beau MM, et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood. 114: 144-7. PMID 19420352 DOI: 10.1182/blood-2009-03-210039  0.52
2009 Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, Harris NL, Le Beau MM, Hellström-Lindberg E, Tefferi A, Bloomfield CD. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 114: 937-51. PMID 19357394 DOI: 10.1182/blood-2009-03-209262  0.52
2009 Knight JA, Skol AD, Shinde A, Hastings D, Walgren RA, Shao J, Tennant TR, Banerjee M, Allan JM, Le Beau MM, Larson RA, Graubert TA, Cox NJ, Onel K. Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility. Blood. 113: 5575-82. PMID 19299336 DOI: 10.1182/blood-2008-10-183244  0.52
2008 Li Z, Lu J, Sun M, Mi S, Zhang H, Luo RT, Chen P, Wang Y, Yan M, Qian Z, Neilly MB, Jin J, Zhang Y, Bohlander SK, Zhang DE, ... ... Le Beau MM, et al. Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proceedings of the National Academy of Sciences of the United States of America. 105: 15535-40. PMID 18832181 DOI: 10.1073/pnas.0808266105  0.52
2008 Qian Z, Chen L, Fernald AA, Williams BO, Le Beau MM. A critical role for Apc in hematopoietic stem and progenitor cell survival. The Journal of Experimental Medicine. 205: 2163-75. PMID 18725524 DOI: 10.1084/jem.20080578  0.52
2008 Ellis NA, Huo D, Yildiz O, Worrillow LJ, Banerjee M, Le Beau MM, Larson RA, Allan JM, Onel K. MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility. Blood. 112: 741-9. PMID 18426989 DOI: 10.1182/blood-2007-11-126508  0.52
2008 Kirsammer G, Jilani S, Liu H, Davis E, Gurbuxani S, Le Beau MM, Crispino JD. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood. 111: 767-75. PMID 17901249 DOI: 10.1182/blood-2007-04-085670  0.52
2007 Mi S, Lu J, Sun M, Li Z, Zhang H, Neilly MB, Wang Y, Qian Z, Jin J, Zhang Y, Bohlander SK, Le Beau MM, Larson RA, Golub TR, Rowley JD, et al. MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 104: 19971-6. PMID 18056805 DOI: 10.1073/pnas.0709313104  0.52
2007 Lucas I, Palakodeti A, Jiang Y, Young DJ, Jiang N, Fernald AA, Le Beau MM. High-throughput mapping of origins of replication in human cells. Embo Reports. 8: 770-7. PMID 17668008 DOI: 10.1038/sj.embor.7401026  0.52
2007 Joslin JM, Fernald AA, Tennant TR, Davis EM, Kogan SC, Anastasi J, Crispino JD, Le Beau MM. Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood. 110: 719-26. PMID 17420284 DOI: 10.1182/blood-2007-01-068809  0.52
2007 Markus J, Garin MT, Bies J, Galili N, Raza A, Thirman MJ, Le Beau MM, Rowley JD, Liu PP, Wolff L. Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16). Cancer Research. 67: 992-1000. PMID 17283131 DOI: 10.1158/0008-5472.CAN-06-2964  0.52
2007 Singh ZN, Huo D, Anastasi J, Smith SM, Karrison T, Le Beau MM, Larson RA, Vardiman JW. Therapy-related myelodysplastic syndrome: morphologic subclassification may not be clinically relevant. American Journal of Clinical Pathology. 127: 197-205. PMID 17210514 DOI: 10.1309/NQ3PMV4U8YV39JWJ  0.52
2007 Boyapati A, Yan M, Peterson LF, Biggs JR, Le Beau MM, Zhang DE. A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy. Blood. 109: 3963-71. PMID 17197431 DOI: 10.1182/blood-2006-09-045583  0.52
2007 Lones MA, Heerema NA, Le Beau MM, Sposto R, Perkins SL, Kadin ME, Kjeldsberg CR, Meadows A, Siegel S, Buckley J, Abromowitch M, Kersey J, Bergeron S, Cairo MS, Sanger WG. Chromosome abnormalities in advanced stage lymphoblastic lymphoma of children and adolescents: a report from CCG-E08 Cancer Genetics and Cytogenetics. 172: 1-11. PMID 17175373 DOI: 10.1016/j.cancergencyto.2006.07.011  0.52
2006 Lones MA, Heerema NA, Le Beau MM, Perkins SL, Kadin ME, Kjeldsberg CR, Sposto R, Meadows A, Siegel S, Buckley J, Finlay J, Abromowitch M, Cairo MS, Sanger WG. Complex secondary chromosome abnormalities in advanced stage anaplastic large cell lymphoma of children and adolescents: a report from CCG-E08. Cancer Genetics and Cytogenetics. 171: 89-96. PMID 17116485 DOI: 10.1016/j.cancergencyto.2006.04.019  0.52
2006 Djokic M, Le Beau MM, Swinnen LJ, Smith SM, Rubin CM, Anastasi J, Carlson KM. Post-transplant lymphoproliferative disorder subtypes correlate with different recurring chromosomal abnormalities. Genes, Chromosomes & Cancer. 45: 313-8. PMID 16283619 DOI: 10.1002/gcc.20287  0.52
2005 Luo H, Li Q, O'Neal J, Kreisel F, Le Beau MM, Tomasson MH. c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations. Blood. 106: 2452-61. PMID 15972450 DOI: 10.1182/blood-2005-02-0734  0.52
2005 Larson RA, Le Beau MM. Therapy-related myeloid leukaemia: a model for leukemogenesis in humans. Chemico-Biological Interactions. 153: 187-95. PMID 15935816 DOI: 10.1016/j.cbi.2005.03.023  0.52
2005 Curtiss NP, Bonifas JM, Lauchle JO, Balkman JD, Kratz CP, Emerling BM, Green ED, Le Beau MM, Shannon KM. Isolation and analysis of candidate myeloid tumor suppressor genes from a commonly deleted segment of 7q22. Genomics. 85: 600-7. PMID 15820312 DOI: 10.1016/j.ygeno.2005.01.013  0.52
2004 Lones MA, Sanger WG, Le Beau MM, Heerema NA, Sposto R, Perkins SL, Buckley J, Kadin ME, Kjeldsberg CR, Meadows A, Siegel S, Finlay J, Bergeron S, Cairo MS. Chromosome abnormalities may correlate with prognosis in Burkitt/Burkitt-like lymphomas of children and adolescents: a report from Children's Cancer Group Study CCG-E08. Journal of Pediatric Hematology/Oncology. 26: 169-78. PMID 15125609 DOI: 10.1097/00043426-200403000-00006  0.52
2004 Kebriaei P, Winter JN, Laport GG, Le Beau MM, Dewald G, Larson RA. Multiple unrelated clonal abnormalities in host bone marrow cells after allogeneic stem cell transplantation. Leukemia Research. 28: 537-40. PMID 15068908 DOI: 10.1016/j.leukres.2003.09.010  0.4
2004 Side LE, Curtiss NP, Teel K, Kratz C, Wang PW, Larson RA, Le Beau MM, Shannon KM. RAS, FLT3, and TP53 mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7. Genes, Chromosomes & Cancer. 39: 217-23. PMID 14732923 DOI: 10.1002/gcc.10320  0.4
2004 Braun BS, Tuveson DA, Kong N, Le DT, Kogan SC, Rozmus J, Le Beau MM, Jacks TE, Shannon KM. Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder. Proceedings of the National Academy of Sciences of the United States of America. 101: 597-602. PMID 14699048 DOI: 10.1073/pnas.0307203101  0.52
2004 Palakodeti A, Han Y, Jiang Y, Le Beau MM. The role of late/slow replication of the FRA16D in common fragile site induction. Genes, Chromosomes & Cancer. 39: 71-6. PMID 14603443 DOI: 10.1002/gcc.10290  0.68
2003 Ranger AM, Zha J, Harada H, Datta SR, Danial NN, Gilmore AP, Kutok JL, Le Beau MM, Greenberg ME, Korsmeyer SJ. Bad-deficient mice develop diffuse large B cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 100: 9324-9. PMID 12876200 DOI: 10.1073/pnas.1533446100  0.52
2003 Phan VT, Shultz DB, Truong BT, Blake TJ, Brown AL, Gonda TJ, Le Beau MM, Kogan SC. Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation. Molecular and Cellular Biology. 23: 4573-85. PMID 12808098 DOI: 10.1128/MCB.23.13.4573-4585.2003  0.52
2003 Le Beau MM, Davis EM, Patel B, Phan VT, Sohal J, Kogan SC. Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia. Blood. 102: 1072-4. PMID 12689927 DOI: 10.1182/blood-2003-01-0155  0.52
2003 Lensch MW, Tischkowitz M, Christianson TA, Reifsteck CA, Speckhart SA, Jakobs PM, O'Dwyer ME, Olson SB, Le Beau MM, Hodgson SV, Mathew CG, Larson RA, Bagby GC. Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia. Blood. 102: 7-16. PMID 12637330 DOI: 10.1182/blood-2002-09-2781  0.4
2003 Smith SM, Le Beau MM, Huo D, Karrison T, Sobecks RM, Anastasi J, Vardiman JW, Rowley JD, Larson RA. Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series. Blood. 102: 43-52. PMID 12623843 DOI: 10.1182/blood-2002-11-3343  0.52
2002 Qian Z, Fernald AA, Godley LA, Larson RA, Le Beau MM. Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 99: 14925-30. PMID 12417757 DOI: 10.1073/pnas.222491799  0.52
2002 Bender CF, Sikes ML, Sullivan R, Huye LE, Le Beau MM, Roth DB, Mirzoeva OK, Oltz EM, Petrini JH. Cancer predisposition and hematopoietic failure in Rad50(S/S) mice. Genes & Development. 16: 2237-51. PMID 12208847 DOI: 10.1101/gad.1007902  0.52
2002 Sato Y, Izumi T, Kanamori H, Davis EM, Miura Y, Larson RA, Le Beau MM, Ozawa K, Rowley JD. t(1;3)(p36;p21) is a recurring therapy-related translocation. Genes, Chromosomes & Cancer. 34: 186-92. PMID 11979552 DOI: 10.1002/gcc.10055  0.4
2002 Kosak ST, Skok JA, Medina KL, Riblet R, Le Beau MM, Fisher AG, Singh H. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science (New York, N.Y.). 296: 158-62. PMID 11935030 DOI: 10.1126/science.1068768  0.52
2002 Le Beau MM, Bitts S, Davis EM, Kogan SC. Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia. Blood. 99: 2985-91. PMID 11929790 DOI: 10.1182/blood.V99.8.2985  0.52
2002 Abe MK, Saelzler MP, Espinosa R, Kahle KT, Hershenson MB, Le Beau MM, Rosner MR. ERK8, a new member of the mitogen-activated protein kinase family. The Journal of Biological Chemistry. 277: 16733-43. PMID 11875070 DOI: 10.1074/jbc.M112483200  0.52
2002 Zhang Y, Strissel P, Strick R, Chen J, Nucifora G, Le Beau MM, Larson RA, Rowley JD. Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia. Proceedings of the National Academy of Sciences of the United States of America. 99: 3070-5. PMID 11867721 DOI: 10.1073/pnas.042702899  0.4
2002 Kratz CP, Emerling BM, Bonifas J, Wang W, Green ED, Le Beau MM, Shannon KM. Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor. Blood. 99: 372-4. PMID 11756194 DOI: 10.1182/blood.V99.1.372  0.52
2001 Kratz CP, Emerling BM, Donovan S, Laig-Webster M, Taylor BR, Thompson P, Jensen S, Banerjee A, Bonifas J, Makalowski W, Green ED, Le Beau MM, Shannon KM. Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies. Genomics. 77: 171-80. PMID 11597142 DOI: 10.1006/geno.2001.6636  0.52
2001 Shannon KM, Le Beau MM, Largaespada DA, Killeen N. Modeling myeloid leukemia tumor suppressor gene inactivation in the mouse Seminars in Cancer Biology. 11: 191-199. PMID 11407944 DOI: 10.1006/scbi.2001.0372  0.52
2001 Lai F, Godley LA, Joslin J, Fernald AA, Liu J, Espinosa R, Zhao N, Pamintuan L, Till BG, Larson RA, Qian Z, Le Beau MM. Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q). Genomics. 71: 235-45. PMID 11161817 DOI: 10.1006/geno.2000.6414  0.52
2000 Buckley JD, Meadows AT, Kadin ME, Le Beau MM, Siegel S, Robison LL. Pesticide exposures in children with non-Hodgkin lymphoma Cancer. 89: 2315-2321. PMID 11147603 DOI: 10.1002/1097-0142(20001201)89:11<2315::AID-CNCR21>3.0.CO;2-G  0.52
2000 Lai F, Godley LA, Fernald AA, Orelli BJ, Pamintuan L, Zhao N, Le Beau MM. cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins. Genomics. 70: 123-30. PMID 11087669 DOI: 10.1006/geno.2000.6345  0.52
2000 Lai F, Orelli BJ, Till BG, Godley LA, Fernald AA, Pamintuan L, Le Beau MM. Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene. Genomics. 66: 65-75. PMID 10843806 DOI: 10.1006/geno.2000.6181  0.52
2000 Lai F, Fernald AA, Zhao N, Le Beau MM. cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene. Gene. 248: 117-25. PMID 10806357 DOI: 10.1016/S0378-1119(00)00135-9  0.52
1999 Wang PW, Eisenbart JD, Cordes SP, Barsh GS, Stoffel M, Le Beau MM. Human KRML (MAFB): cDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. Genomics. 59: 275-81. PMID 10444328 DOI: 10.1006/geno.1999.5884  0.52
1999 Stoffel A, Rao PH, Louie DC, Krauter K, Liebowitz DN, Koeppen H, Le Beau MM, Chaganti RSK. Chromosome 18 breakpoint in t(11;18)(q21;q21) translocation associated with MALT lymphoma is proximal to BCL2 and distal to DCC Genes Chromosomes and Cancer. 24: 156-159. PMID 9885983 DOI: 10.1002/(SICI)1098-2264(199902)24:2<156::AID-GCC9>3.0.CO;2-X  0.52
1998 Zhao N, Lai F, Fernald AA, Eisenbart JD, Espinosa R, Wang PW, Le Beau MM. Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. Genomics. 53: 184-90. PMID 9790767 DOI: 10.1006/geno.1998.5473  0.52
1998 Weng Z, Fluckiger AC, Nisitani S, Wahl MI, Le LQ, Hunter CA, Fernal AA, Le Beau MM, Witte ON. A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M. Proceedings of the National Academy of Sciences of the United States of America. 95: 12334-9. PMID 9770487 DOI: 10.1073/pnas.95.21.12334  0.52
1998 Chen M, She H, Davis EM, Spicer CM, Kim L, Ren R, Le Beau MM, Li W. Identification of Nck family genes, chromosomal localization, expression, and signaling specificity. The Journal of Biological Chemistry. 273: 25171-8. PMID 9737977 DOI: 10.1074/jbc.273.39.25171  0.52
1998 Furuta H, Horikawa Y, Iwasaki N, Hara M, Sussel L, Le Beau MM, Davis EM, Ogata M, Iwamoto Y, German MS, Bell GI. β-cell transcription factors and diabetes: Mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese Diabetes. 47: 1356-1358. PMID 9703340 DOI: 10.2337/diabetes.47.8.1356  0.52
1998 Nishigori H, Yamada S, Tomura H, Fernald AA, Le Beau MM, Takeuchi T, Takeda J. Identification and characterization of the gene encoding a second proteolipid subunit of human vacuolar H(+)-ATPase (ATP6F). Genomics. 50: 222-8. PMID 9653649 DOI: 10.1006/geno.1998.5310  0.52
1997 Vaisse C, Kim J, Espinosa R, Le Beau MM, Stoffel M. Pancreatic islet expression studies and polymorphic DNA markers in the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6. Diabetes. 46: 1364-7. PMID 9231664 DOI: 10.2337/diab.46.8.1364  0.52
1997 Janßen U, Davis EM, Le Beau MM, Stoffel W. Human mitochondrial enoyl-CoA hydratase gene (ECHS1): Structural organization and assignment to chromosome 10q26.2-q26.3 Genomics. 40: 470-475. PMID 9073515 DOI: 10.1006/geno.1996.4597  0.52
1997 Espinosa R, Le Beau MM. Gene mapping by FISH Methods in Molecular Biology (Clifton, N.J.). 68: 53-76. PMID 9055250 DOI: 10.1385/0-89603-482-8:53  0.52
1997 Broccoli D, Chong L, Oelmann S, Fernald AA, Marziliano N, van Steensel B, Kipling D, Le Beau MM, de Lange T. Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains. Human Molecular Genetics. 6: 69-76. PMID 9002672 DOI: 10.1093/hmg/6.1.69  0.52
1996 Furuta H, Nishi S, Le Beau MM, Fernald AA, Yano H, Bell GI. Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization. Genomics. 36: 206-9. PMID 8812439 DOI: 10.1006/geno.1996.0448  0.52
1996 Rassool FV, Le Beau MM, Shen ML, Neilly ME, Espinosa R, Ong ST, Boldog F, Drabkin H, McCarroll R, McKeithan TW. Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2 Genomics. 35: 109-117. PMID 8661111 DOI: 10.1006/geno.1996.0329  0.52
1996 Bosio A, Binczek E, Le Beau MM, Fernald AA, Stoffel W. The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26. Genomics. 34: 69-75. PMID 8661025 DOI: 10.1006/geno.1996.0242  0.52
1995 Valenzuela DM, Rojas E, Le Beau MM, Espinosa R, Brannan CI, McClain J, Masiakowski P, Ip NY, Copeland NG, Jenkins NA. Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor. Genomics. 25: 157-63. PMID 7774913 DOI: 10.1016/0888-7543(95)80121-2  0.52
1995 Tsaur ML, Menzel S, Lai FP, Espinosa R, Concannon P, Spielman RS, Hanis CL, Cox NJ, Le Beau MM, German MS. Isolation of a cDNA clone encoding a KATP channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM. Diabetes. 44: 592-6. PMID 7729621  0.52
1995 Takeda J, Fernald AA, Yamagata K, Le Beau MM, Bell GI. Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization. Genomics. 26: 638-9. PMID 7607700 DOI: 10.1016/0888-7543(95)80195-R  0.52
1995 Rassool FV, Neilly ME, McGuire KL, McKeithan TW, Le Beau MM. Localization of the chinese hamster MHC locus to chromosome 1q17→q18 by fluorescence in situ hybridization Cytogenetic and Genome Research. 71: 62-63. PMID 7606930 DOI: 10.1159/000134064  0.52
1995 Jones EM, Fernald A, Bell GI, Le Beau MM. Assignment of SLC6A9 to human chromosome band 1p33 by in situ hybridization. Cytogenetics and Cell Genetics. 71: 211. PMID 7587377 DOI: 10.1159/000134110  0.52
1995 el-Maghrabi MR, Lange AJ, Jiang W, Yamagata K, Stoffel M, Takeda J, Fernald AA, Le Beau MM, Bell GI, Baker L. Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency. Genomics. 27: 520-5. PMID 7558035 DOI: 10.1006/geno.1995.1085  0.52
1995 Stoffel M, Fernald AA, Le Beau MM, Bell GI. Assignment of the gastric inhibitory polypeptide receptor gene (GIPR) to chromosome bands 19q13.2-q13.3 by fluorescence in situ hybridization. Genomics. 28: 607-9. PMID 7490109 DOI: 10.1006/geno.1995.1203  0.52
1994 Bohlander SK, Espinosa R, Fernald AA, Rowley JD, Le Beau MM, Díaz MO. Sequence-independent amplification and labeling of yeast artificial chromosomes for fluorescence in situ hybridization. Cytogenetics and Cell Genetics. 65: 108-10. PMID 8404060  0.52
1994 Le Beau MM, Carver LA, Espinosa R, Schmidt JV, Bradfield CA. Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-->p15. Cytogenetics and Cell Genetics. 66: 172-6. PMID 8125016  0.52
1994 Stoffel M, Espinosa R, Powell KL, Philipson LH, Le Beau MM, Bell GI. Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): Localization to chromosome 2 and identification of a simple tandem repeat polymorphism Genomics. 21: 254-256. PMID 8088798 DOI: 10.1006/geno.1994.1253  0.52
1994 Menzel S, Stoffel M, Espinosa R, Fernald AA, Le Beau MM, Bell GI. Localization of the glucagon receptor gene to human chromosome band 17q25. Genomics. 20: 327-8. PMID 8020989 DOI: 10.1006/geno.1994.1179  0.52
1994 German MS, Wang J, Fernald AA, Espinosa R, Le Beau MM, Bell GI. Localization of the genes encoding two transcription factors, LMX1 and CDX3, regulating insulin gene expression to human chromosomes 1 and 13. Genomics. 24: 403-4. PMID 7698771 DOI: 10.1006/geno.1994.1639  0.52
1993 Le Beau MM, Espinosa R, Neuman WL, Stock W, Roulston D, Larson RA, Keinanen M, Westbrook CA. Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases. Proceedings of the National Academy of Sciences of the United States of America. 90: 5484-8. PMID 8516290 DOI: 10.1073/pnas.90.12.5484  0.4
1993 Kobayashi H, Espinosa R, Thirman MJ, Gill HJ, Fernald AA, Diaz MO, Le Beau MM, Rowley JD. Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization. Blood. 82: 547-51. PMID 8329710  0.52
1993 Yasuda K, Espinosa R, Davis EM, Le Beau MM, Bell GI. Human somatostatin receptor genes: Localization of SSTR5 to human chromosome 20p11.2 Genomics. 17: 785-786. PMID 8244401 DOI: 10.1006/geno.1993.1410  0.52
1993 Kobayashi H, Espinosa R, Thirman MJ, Fernald AA, Shannon K, Diaz MO, Le Beau MM, Rowley JD. Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization. Genes, Chromosomes & Cancer. 7: 204-8. PMID 7692945  0.52
1993 Sanford JP, Sait SNJ, Pan L, Nowak NJ, Gill HJ, Le Beau MM, Diaz MO, Zabel B, Shows TB. Characterization of two 11q23.3-11q24 deletions and mapping of associated anonymous DNA markers Genes Chromosomes and Cancer. 7: 67-73. PMID 7687455 DOI: 10.1002/gcc.2870070202  0.52
1993 Kobayashi H, Espinosa R, Fernald AA, Begy C, Diaz MO, Le Beau MM, Rowley JD. Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization. Genes, Chromosomes & Cancer. 8: 246-52. PMID 7512368 DOI: 10.1002/gcc.2870080407  0.52
1992 Davey FR, Lawrence D, MacCallum J, Varney J, Hutchison R, Wurster-Hill D, Schiffer C, Sobol RE, Ciminelli N, Le Beau M, Bloomfield CD. Morphologic characteristics of acute lymphoblastic leukemie (ALL) with abnormalities of chromosome 8, band q24 American Journal of Hematology. 40: 183-191. PMID 1609772 DOI: 10.1002/ajh.2830400306  0.52
1992 Wagner AJ, Le Beau MM, Diaz MO, Hay N. Expression, regulation, and chromosomal localization of the Max gene Proceedings of the National Academy of Sciences of the United States of America. 89: 3111-3115. PMID 1557420  0.52
1992 Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO. Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia Genomics. 14: 437-443. PMID 1385305 DOI: 10.1016/S0888-7543(05)80238-1  0.52
1992 Park JK, Le Beau MM, Shows TB, Rowley JD, Diaz MO. A complex genetic rearrangement in a t(10;14)(q24;q11) associated with T- cell acute lymphoblastic leukemia Genes Chromosomes and Cancer. 4: 32-40. PMID 1377007  0.52
1992 Ip NY, Ibáñez CF, Nye SH, McClain J, Jones PF, Gies DR, Belluscio L, Le Beau MM, Espinosa R, Squinto SP. Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity. Proceedings of the National Academy of Sciences of the United States of America. 89: 3060-4. PMID 1313578 DOI: 10.1073/pnas.89.7.3060  0.52
1992 Dixon MJ, Dixon J, Raskova D, Le Beau MM, Williamson R, Klinger K, Landes GM. Genetic and physical mapping of the Treacher Collins syndrome locus: refinement of the localization to chromosome 5q32-33.2. Human Molecular Genetics. 1: 249-53. PMID 1303194 DOI: 10.1093/hmg/1.4.249  0.52
1991 Gao J, Erickson P, Gardiner K, Le Beau MM, Diaz MO, Patterson D, Rowley JD, Drabkin HA. Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21)(q22;q22.3) in acute myelogenous leukemia Proceedings of the National Academy of Sciences of the United States of America. 88: 4882-4886. PMID 2052570  0.52
1991 Lorenzana AN, Rubin CM, Le Beau MM, Nachman J, Connolly P, Subramanian U, Johnson FL, McKeithan TW. Immunoglobulin gene rearrangements in acute lymphoblastic leukemia with the 9;11 translocation. Genes, Chromosomes & Cancer. 3: 74-7. PMID 1906342 DOI: 10.1002/gcc.2870030113  0.52
1991 Maisonpierre PC, Le Beau MM, Espinosa R, Ip NY, Belluscio L, de la Monte SM, Squinto S, Furth ME, Yancopoulos GD. Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations. Genomics. 10: 558-68. PMID 1889806 DOI: 10.1016/0888-7543(91)90436-I  0.52
1991 Burnett RC, David JC, Harden AM, Le Beau MM, Rowley JD, Diaz MO. The LCK gene is involved in the t(1;7)(p34;q34) in the T-cell acute lymphoblastic leukemia derived cell line, HSB-2. Genes, Chromosomes & Cancer. 3: 461-7. PMID 1663780 DOI: 10.1002/gcc.2870030608  0.52
1990 Lemons RS, Espinosa R, Rebentisch M, McCormick F, Ladner M, Le Beau MM. Chromosomal localization of the gene encoding GTPase-activating protein (RASA) to human chromosome 5, bands q13-q15. Genomics. 6: 383-5. PMID 2307479 DOI: 10.1016/0888-7543(90)90581-E  0.52
1990 Chada S, Le Beau MM, Casey L, Newburger PE. Isolation and chromosomal localization of the human glutathione peroxidase gene Genomics. 6: 268-271. PMID 2307470 DOI: 10.1016/0888-7543(90)90566-D  0.52
1990 Diaz MO, Rubin CM, Harden A, Ziemin S, Larson RA, Le Beau MM, Rowley JD. Deletions of interferon genes in acute lymphoblastic leukemia. The New England Journal of Medicine. 322: 77-82. PMID 2294436 DOI: 10.1056/NEJM199001113220202  0.52
1990 Becker MA, Heidler SA, Bell GI, Seino S, Le Beau MM, Westbrook CA, Neuman W, Shapiro LJ, Mohandas TK, Roessler BJ. Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes. Genomics. 8: 555-61. PMID 1962753 DOI: 10.1016/0888-7543(90)90043-T  0.52
1990 Good DJ, Polverini PJ, Rastinejad F, Le Beau MM, Lemons RS, Frazier WA, Bouck NP. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proceedings of the National Academy of Sciences of the United States of America. 87: 6624-8. PMID 1697685 DOI: 10.1073/pnas.87.17.6624  0.52
1989 Park JK, McKeithan TW, Le Beau MM, Bitter MA, Frankli n WA, Rowley JD, Diaz MO. An (8;14)(q24;q11) translocation involving the T-cell receptor α-chain gene and the MYC oncogene 3' region in a B-cell lymphoma Genes Chromosomes and Cancer. 1: 15-22. PMID 2535034  0.52
1988 Harris BN, Davis EM, Le Beau MM, Bitter MA, Kaminer LS, Morgan E, Rowley JD. Variant translocations (9;11): identification of the critical genetic rearrangement. Cancer Genetics and Cytogenetics. 30: 171-5. PMID 3422044 DOI: 10.1016/0165-4608(88)90108-2  0.52
1988 Wetsel RA, Lemons RS, Le Beau MM, Barnum SR, Noack D, Tack BF. Molecular analysis of human complement component C5: Localization of the structural gene to chromosome 9 Biochemistry. 27: 1474-1482. PMID 3365401  0.52
1988 Martin AO, Northrup H, Ledbetter DH, Trask B, van den Engh G, Le Beau MM, Beaudet AL, Gray JW, Sekhon G, Krassikoff N. Prenatal detection of 46,XY,rec(5),dup q, inv(5)(p13q33) using DNA analysis, flow cytometry, and in situ hybridization to supplement classical cytogenetic analysis. American Journal of Medical Genetics. 31: 643-54. PMID 3228143 DOI: 10.1002/ajmg.1320310320  0.52
1988 Li YS, Anastasi J, Larson RA, Le Beau MM, Vardiman JW, Rowley JD. A recurring chromosome rearrangement, dic(16;22), in acute nonlymphocytic leukemia Cancer Genetics and Cytogenetics. 35: 143-150. PMID 3180017 DOI: 10.1016/0165-4608(88)90235-X  0.52
1988 Anastasi J, Pettenati MJ, Le Beau MM, Kwaan HC, Weil SC. Acute lymphoblastic leukemia in a patient with longstanding polycythemia vera: Cytogenetic analysis reveals two distinct abnormal clones American Journal of Hematology. 29: 33-37. PMID 3177367 DOI: 10.1002/ajh.2830290108  0.52
1988 Joseph LJ, Le Beau MM, Jamieson GA, Acharya S, Shows TB, Rowley JD, Sukhatme VP. Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure. Proceedings of the National Academy of Sciences of the United States of America. 85: 7164-8. PMID 3140236 DOI: 10.1073/pnas.85.19.7164  0.52
1988 Diaz MO, Ziemin S, Le Beau MM, Pitha P, Smith SD, Chilcote RR, Rowley JD. Homozygous deletion of the α- and β1-interferon genes in human leukemia and derived cell lines Proceedings of the National Academy of Sciences of the United States of America. 85: 5259-5263. PMID 3134658 DOI: 10.1073/pnas.85.14.5259  0.52
1988 Weil SC, Rosner GL, Reid MS, Chisholm RL, Lemons RS, Swanson MS, Carrino JJ, Diaz MO, Le Beau MM. Translocation and rearrangement of myeloperoxidase gene in acute promyelocytic leukemia. Science (New York, N.Y.). 240: 790-2. PMID 2896388  0.52
1987 Le Beau MM, Epstein ND, O'Brien SJ, Nienhuis AW, Yang YC, Clark SC, Rowley JD. The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q Proceedings of the National Academy of Sciences of the United States of America. 84: 5913-5917. PMID 3497400 DOI: 10.1073/pnas.84.16.5913  0.52
1987 Quintrell N, Lebo R, Varmus H, Bishop JM, Pettenati MJ, Le Beau MM, Diaz MO, Rowley JD. Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells Molecular and Cellular Biology. 7: 2267-2275. PMID 3496523 DOI: 10.1128/MCB.7.6.2267  0.52
1987 Pettenati MJ, Le Beau MM, Lemons RS, Shima EA, Kawasaki ES, Larson RA, Sherr CJ, Diaz MO, Rowley JD. Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders. Proceedings of the National Academy of Sciences of the United States of America. 84: 2970-4. PMID 3495006 DOI: 10.1073/pnas.84.9.2970  0.52
1987 Rubin CM, Larson RA, Bitter MA, Carrino JJ, Le Beau MM, Diaz MO, Rowley JD. Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia Blood. 70: 1338-1342. PMID 3478099  0.52
1987 Ackland SP, Westbrook CA, Diaz MO, Le Beau MM, Rowley JD. Evidence favoring lineage fidelity in acute nonlymphocytic leukemia: absence of immunoglobulin gene rearrangements in FAB types M4 and M5. Blood. 69: 87-91. PMID 3098329  0.52
1987 Westbrook CA, Rubin CM, Le Beau MM, Kaminer LS, Smith SD, Rowley JD, Diaz MO. Molecular analysis of TCRB and ABL in a t(7;9)-containing cell line (SUP-T3) from a human T-cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 84: 251-5. PMID 3025859 DOI: 10.1073/pnas.84.1.251  0.52
1987 Lublin DM, Lemons RS, Le Beau MM, Holers VM, Tykocinski ML, Medof ME, Atkinson JP. The gene encoding decay-accelerating factor (DAF) is located in the complement-regulatory locus on the long arm of chromosome 1 Journal of Experimental Medicine. 165: 1731-1736. PMID 2438369 DOI: 10.1084/jem.165.6.1731  0.52
1986 Le Beau MM, McKeithan TW, Shima EA, Goldman-Leikin RE, Chan SJ, Bell GI, Rowley JD, Diaz MO. T-cell receptor α-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11) Proceedings of the National Academy of Sciences of the United States of America. 83: 9744-9748. PMID 3540949  0.52
1986 McKeithan TW, Shima EA, Le Beau MM, Minowada J, Rowley JD, Diaz MO. Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor α-chain gene and sequences on the 3' side of MYC Proceedings of the National Academy of Sciences of the United States of America. 83: 6636-6640. PMID 3529089 DOI: 10.1073/pnas.83.17.6636  0.52
1986 Shima EA, Le Beau MM, McKeithan TW, Minowada J, Showe LC, Mak TW, Minden MD, Rowley JD, Diaz MO. Gene encoding the alpha chain of the T-cell receptor is moved immediately downstream of c-myc in a chromosomal 8;14 translocation in a cell line from a human T-cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 83: 3439-43. PMID 3517860  0.52
1986 Le Beau MM, Pettenati MJ, Lemons RS, Diaz MO, Westbrook CA, Larson RA, Sherr CJ, Rowley JD. Assignment of the GM-CSF, CSF-1, and FMS genes to human chromosome 5 provides evidence for linkage of a family of genes regulating hematopoiesis and for their involvement in the deletion (5q) in myeloid disorders. Cold Spring Harbor Symposia On Quantitative Biology. 51: 899-909. PMID 3495397  0.52
1986 Le Beau MM, Westbrook CA, Diaz MO, Larson RA, Rowley JD, Gasson JC, Golde DW, Sherr CJ. Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders. Science (New York, N.Y.). 231: 984-7. PMID 3484837 DOI: 10.1126/science.3484837  0.52
1986 Diaz MO, Le Beau MM, Pitha P, Rowley JD. Interferon and c-ets-1 genes in the translocation (9;11)(p22;q23) in human acute monoytic leukemia Science. 231: 265-267. PMID 3455787  0.52
1986 Le Beau MM, Rowley JD, Sacchi N, Watson DK, Papas TS, Diaz MO. Hu-ets-2 is translocated to chromosome 8 in the t(8;21) in acute myelogenous leukemia Cancer Genetics and Cytogenetics. 23: 269-274. PMID 3021321 DOI: 10.1016/0165-4608(86)90189-5  0.52
1986 Look AT, Peiper SC, Rebentisch MB, Ashmun RA, Roussel MF, Lemons RS, Le Beau MM, Rubin CM, Sherr CJ. Molecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150) Journal of Clinical Investigation. 78: 914-921. PMID 2428842 DOI: 10.1172/JCI112680  0.52
1985 Diaz MO, Le Beau MM, Harden A, Rowley JD. Trisomy 8 in human hematologic neoplasia and the c-myc and c-mos oncogenes. Leukemia Research. 9: 1437-42. PMID 4079453 DOI: 10.1016/0145-2126(85)90033-5  0.52
1985 Westbrook CA, Le Beau MM, Diaz MO, Groffen J, Rowley JD. Chromosomal localization and characterization of c-abl in the t(6;9) of acute nonlymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 82: 8742-6. PMID 3866248  0.52
1985 Diaz MO, Le Beau MM, Rowley JD, Drabkin HA, Patterson D. The role of the c-mos gene in the 8;21 translocation in human acute myeloblastic leukemia Science. 229: 767-769. PMID 3860954 DOI: 10.1126/science.3860954  0.52
1985 Drabkin HA, Diaz M, Bradley CM, Le Beau MM, Rowley JD, Patterson D. Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: Evidence that c-mos is not translocated Proceedings of the National Academy of Sciences of the United States of America. 82: 464-468. PMID 2982159 DOI: 10.1073/pnas.82.2.464  0.52
1985 Le Beau MM, Westbrook CA, Diaz MO, Rowley JD. c-src is consistently conserved in the chromosomal deletion (20q) observed in myeloid disorders. Proceedings of the National Academy of Sciences of the United States of America. 82: 6692-6. PMID 2413444  0.52
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