Year |
Citation |
Score |
2021 |
Zolkowska D, Dhir A, Rogawski MA. Perampanel, a potent AMPA receptor antagonist, protects against tetramethylenedisulfotetramine-induced seizures and lethality in mice: comparison with diazepam. Archives of Toxicology. PMID 33914090 DOI: 10.1007/s00204-021-03053-9 |
0.624 |
|
2020 |
Dhir A, Bruun DA, Guignet M, Tsai YH, González E, Calsbeek J, Vu J, Saito N, Tancredi DJ, Harvey DJ, Lein PJ, Rogawski MA. Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats. Annals of the New York Academy of Sciences. PMID 32915470 DOI: 10.1111/Nyas.14479 |
0.635 |
|
2020 |
Dhir A. Ubrogepant to treat migraine. Drugs of Today. 56: 459-467. PMID 32648856 DOI: 10.1358/Dot.2020.56.7.3157311 |
0.38 |
|
2020 |
Dhir A. Cenobamate for the treatment of focal epilepsy. Drugs of Today. 56: 233-240. PMID 32309819 DOI: 10.1358/Dot.2020.56.4.3127030 |
0.483 |
|
2020 |
González EA, Rindy AC, Guignet MA, Calsbeek JJ, Bruun DA, Dhir A, Andrew P, Saito N, Rowland DJ, Harvey DJ, Rogawski MA, Lein PJ. The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity. Archives of Toxicology. PMID 32303805 DOI: 10.1007/S00204-020-02747-W |
0.608 |
|
2020 |
Dhir A. Natural polyphenols in preclinical models of epilepsy. Phytotherapy Research : Ptr. PMID 32061189 DOI: 10.1002/Ptr.6617 |
0.407 |
|
2019 |
Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Wahab A, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ. Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication. Neurobiology of Disease. PMID 30905768 DOI: 10.1016/J.Nbd.2019.03.019 |
0.567 |
|
2018 |
Dhir A. An update of cyclooxygenase (COX)-inhibitors in epilepsy disorders. Expert Opinion On Investigational Drugs. PMID 30521407 DOI: 10.1080/13543784.2019.1557147 |
0.33 |
|
2018 |
Dhir A. Curcumin in epilepsy disorders. Phytotherapy Research : Ptr. PMID 29917276 DOI: 10.1002/Ptr.6125 |
0.421 |
|
2018 |
Dhir A, Rogawski MA. Determination of minimal steady-state plasma level of diazepam causing seizure threshold elevation in rats. Epilepsia. PMID 29682729 DOI: 10.1111/Epi.14069 |
0.585 |
|
2016 |
Dhir A. Investigational drugs for treating major depressive disorder. Expert Opinion On Investigational Drugs. 1-16. PMID 27960559 DOI: 10.1080/13543784.2017.1267727 |
0.325 |
|
2016 |
Dhir A. Propofol in the treatment of refractory migraine headaches. Expert Review of Neurotherapeutics. PMID 27454834 DOI: 10.1080/14737175.2016.1216795 |
0.321 |
|
2016 |
Dhir A, Chavda V. Pre- and post-exposure talampanel (GYKI 53773) against kainic acid seizures in neonatal rats. Pharmacological Reports : Pr. 68: 190-5. PMID 26721372 DOI: 10.1016/J.Pharep.2015.08.011 |
0.419 |
|
2015 |
Dhir A, Chopra K. On the anticonvulsant effect of allopregnanolone (a neurosteroid) in neonatal rats. Life Sciences. PMID 26400153 DOI: 10.1016/J.Lfs.2015.09.008 |
0.381 |
|
2015 |
Dhir A, Chopra K. Memantine delayed N-methyl-D-aspartate -induced convulsions in neonatal rats. Fundamental & Clinical Pharmacology. 29: 72-8. PMID 25196574 DOI: 10.1111/Fcp.12090 |
0.411 |
|
2014 |
Dhir A, Sarvaiya J. The efficacy of vortioxetine for the treatment of major depressive disorder. Expert Review of Neurotherapeutics. 14: 1349-63. PMID 25418918 DOI: 10.1586/14737175.2014.987131 |
0.338 |
|
2014 |
Zolkowska D, Dhir A, Krishnan K, Covey DF, Rogawski MA. Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms. Psychopharmacology. 231: 3325-32. PMID 24705905 DOI: 10.1007/S00213-014-3546-X |
0.449 |
|
2014 |
Dhir A, Kulkarni SK. Nimesulide, a cyclooxygenase-2 (COX-2) inhibitor counteracts immobilization stress-induced alterations in different behavioral and biochemical parameters in mice Inflammation Research. 56: S481-S487. DOI: 10.1007/Bf03353885 |
0.318 |
|
2013 |
Dhir A. Vortioxetine for the treatment of major depression. Drugs of Today (Barcelona, Spain : 1998). 49: 781-90. PMID 24524096 DOI: 10.1358/Dot.2013.49.12.2058448 |
0.369 |
|
2013 |
Dhir A, Zolkowska D, Rogawski MA. Seizure protection by intrapulmonary delivery of midazolam in mice. Neuropharmacology. 73: 425-31. PMID 23774136 DOI: 10.1016/J.Neuropharm.2013.06.002 |
0.624 |
|
2013 |
Pathak L, Agrawal Y, Dhir A. Natural polyphenols in the management of major depression. Expert Opinion On Investigational Drugs. 22: 863-80. PMID 23642183 DOI: 10.1517/13543784.2013.794783 |
0.3 |
|
2012 |
Dhir A. Pentylenetetrazol (PTZ) kindling model of epilepsy. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit9.37. PMID 23042503 DOI: 10.1002/0471142301.Ns0937S58 |
0.433 |
|
2012 |
Porter RJ, Dhir A, Macdonald RL, Rogawski MA. Mechanisms of action of antiseizure drugs. Handbook of Clinical Neurology. 108: 663-81. PMID 22939059 DOI: 10.1016/B978-0-444-52899-5.00021-6 |
0.539 |
|
2012 |
Dhir A, Lossin C, Rogawski MA. Propofol hemisuccinate suppresses cortical spreading depression. Neuroscience Letters. 514: 67-70. PMID 22390898 DOI: 10.1016/J.Neulet.2012.02.058 |
0.583 |
|
2012 |
Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. The Journal of Pharmacology and Experimental Therapeutics. 341: 435-46. PMID 22328574 DOI: 10.1124/Jpet.111.190579 |
0.629 |
|
2012 |
Dhir A, Rogawski MA. Role of neurosteroids in the anticonvulsant activity of midazolam. British Journal of Pharmacology. 165: 2684-91. PMID 22014182 DOI: 10.1111/J.1476-5381.2011.01733.X |
0.586 |
|
2011 |
Pissurlenkar RS, Dhir A, Kessar SV, Kulkarni SK, Coutinho EC. An activity model for novel antidepressants that interact with the serotonin transporter (SERT). Central Nervous System Agents in Medicinal Chemistry. 11: 228-37. PMID 21919867 DOI: 10.2174/187152411798047762 |
0.302 |
|
2011 |
Dhir A, Kulkarni SK. Antidepressant-like effect of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a putative trace amine receptor ligand involves l-arginine-nitric oxide-cyclic guanosine monophosphate pathway. Neuroscience Letters. 503: 120-4. PMID 21875647 DOI: 10.1016/J.Neulet.2011.08.020 |
0.38 |
|
2011 |
Dhir A, Malik S, Kessar SV, Singh KN, Kulkarni SK. Evaluation of antidepressant activity of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a β-substituted phenylethylamine in mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 705-14. PMID 21277753 DOI: 10.1016/J.Euroneuro.2010.12.003 |
0.438 |
|
2011 |
Dhir A, Zolkowska D, Murphy RB, Rogawski MA. Seizure protection by intrapulmonary delivery of propofol hemisuccinate. The Journal of Pharmacology and Experimental Therapeutics. 336: 215-22. PMID 20837991 DOI: 10.1124/Jpet.110.173591 |
0.607 |
|
2010 |
Dhir A. Novel discoveries in understanding the complexities of epilepsy and major depression. Expert Opinion On Therapeutic Targets. 14: 109-15. PMID 20001214 DOI: 10.1517/14728220903479688 |
0.338 |
|
2009 |
Akula KK, Dhir A, Kulkarni SK. Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice. Methods and Findings in Experimental and Clinical Pharmacology. 31: 423-32. PMID 19907717 DOI: 10.1358/mf.2009.31.7.1393610 |
0.383 |
|
2009 |
Kulkarni S, Dhir A, Akula KK. Potentials of curcumin as an antidepressant. Thescientificworldjournal. 9: 1233-41. PMID 19882093 DOI: 10.1100/Tsw.2009.137 |
0.329 |
|
2009 |
Gupta A, Dhir A, Kumar A, Kulkarni SK. Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats. Pharmacology, Biochemistry, and Behavior. 94: 219-26. PMID 19666045 DOI: 10.1016/J.Pbb.2009.07.018 |
0.378 |
|
2009 |
Kulkarni SK, Dhir A. sigma-1 receptors in major depression and anxiety. Expert Review of Neurotherapeutics. 9: 1021-34. PMID 19589051 DOI: 10.1586/Ern.09.40 |
0.319 |
|
2009 |
Nandal S, Dhir A, Kuhad A, Sharma S, Chopra K. Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model. Methods and Findings in Experimental and Clinical Pharmacology. 31: 89-93. PMID 19455263 DOI: 10.1358/Mf.2009.31.2.1357705 |
0.384 |
|
2009 |
Kulkarni SK, Dhir A. Current investigational drugs for major depression. Expert Opinion On Investigational Drugs. 18: 767-88. PMID 19426122 DOI: 10.1517/13543780902880850 |
0.347 |
|
2009 |
Kulkarni SK, Dhir A. Cyclooxygenase in epilepsy: from perception to application. Drugs of Today (Barcelona, Spain : 1998). 45: 135-54. PMID 19343233 DOI: 10.1358/Dot.2009.45.2.1322481 |
0.333 |
|
2008 |
Kulkarni SK, Deshpande C, Dhir A. Ascorbic Acid inhibits development of tolerance and dependence to opiates in mice: possible glutamatergic or dopaminergic modulation. Indian Journal of Pharmaceutical Sciences. 70: 56-60. PMID 20390081 DOI: 10.4103/0250-474X.40332 |
0.401 |
|
2008 |
Dhir A, Kulkarni SK. Antidepressant-like effect of 17beta-estradiol: involvement of dopaminergic, serotonergic, and (or) sigma-1 receptor systems. Canadian Journal of Physiology and Pharmacology. 86: 726-35. PMID 18841177 DOI: 10.1139/Y08-077 |
0.389 |
|
2008 |
Dhir A, Kulkarni SK. Risperidone, an atypical antipsychotic enhances the antidepressant-like effect of venlafaxine or fluoxetine: possible involvement of alpha-2 adrenergic receptors. Neuroscience Letters. 445: 83-8. PMID 18778754 DOI: 10.1016/J.Neulet.2008.08.074 |
0.425 |
|
2008 |
Dhir A, Kulkarni SK. Possible involvement of sigma-1 receptors in the anti-immobility action of bupropion, a dopamine reuptake inhibitor. Fundamental & Clinical Pharmacology. 22: 387-94. PMID 18705749 DOI: 10.1111/J.1472-8206.2008.00605.X |
0.431 |
|
2008 |
Kulkarni SK, Akula KK, Dhir A. Effect of Withania somnifera Dunal root extract against pentylenetetrazol seizure threshold in mice: possible involvement of GABAergic system. Indian Journal of Experimental Biology. 46: 465-9. PMID 18697606 |
0.387 |
|
2008 |
Kulkarni SK, Dhir A. On the mechanism of antidepressant-like action of berberine chloride. European Journal of Pharmacology. 589: 163-72. PMID 18585703 DOI: 10.1016/J.Ejphar.2008.05.043 |
0.447 |
|
2008 |
Akula KK, Dhir A, Kulkarni SK. Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice. European Journal of Pharmacology. 587: 129-34. PMID 18457833 DOI: 10.1016/J.Ejphar.2008.03.038 |
0.485 |
|
2008 |
Dhir A, Akula KK, Kulkarni SK. Rofecoxib potentiates the anticonvulsant effect of topiramate. Inflammopharmacology. 16: 83-6. PMID 18340407 DOI: 10.1007/S10787-007-7007-6 |
0.441 |
|
2008 |
Dhir A, Kulkarni SK. Venlafaxine reverses chronic fatigue-induced behavioral, biochemical and neurochemical alterations in mice. Pharmacology, Biochemistry, and Behavior. 89: 563-71. PMID 18336891 DOI: 10.1016/J.Pbb.2008.02.011 |
0.344 |
|
2008 |
Dhir A, Kulkarni S. Involvement of sigma (sigma1) receptors in modulating the anti-depressant effect of neurosteroids (dehydroepiandrosterone or pregnenolone) in mouse tail-suspension test. Journal of Psychopharmacology (Oxford, England). 22: 691-6. PMID 18308813 DOI: 10.1177/0269881107082771 |
0.376 |
|
2008 |
Dhir A, Akula KK, Kulkarni SK. Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 835-43. PMID 18234412 DOI: 10.1016/J.Pnpbp.2007.12.017 |
0.368 |
|
2008 |
Akula KK, Dhir A, Kulkarni SK. Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor increases pentylenetetrazol seizure threshold in mice: possible involvement of adenosinergic mechanism. Epilepsy Research. 78: 60-70. PMID 18054463 DOI: 10.1016/J.Eplepsyres.2007.10.008 |
0.513 |
|
2007 |
Akula KK, Dhir A, Kulkarni SK. Systemic administration of adenosine ameliorates pentylenetetrazol-induced chemical kindling and secondary behavioural and biochemical changes in mice. Fundamental & Clinical Pharmacology. 21: 583-94. PMID 18034659 DOI: 10.1111/J.1472-8206.2007.00540.X |
0.475 |
|
2007 |
Akula KK, Dhir A, Kulkarni SK. Pro-convulsant effect of cefazolin sodium against pentylenetetrazol- or picrotoxin-induced convulsions in mice. Indian Journal of Experimental Biology. 45: 720-5. PMID 17877149 |
0.323 |
|
2007 |
Akula KK, Dhir A, Bishnoi M, Kulkarni SK. Effect of systemic administration of adenosine on brain adenosine levels in pentylenetetrazol-induced seizure threshold in mice. Neuroscience Letters. 425: 39-42. PMID 17720312 DOI: 10.1016/J.Neulet.2007.08.006 |
0.461 |
|
2007 |
Dhir A, Kulkarni SK. Involvement of dopamine (DA)/serotonin (5-HT)/sigma (sigma) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist. Brain Research Bulletin. 74: 58-65. PMID 17683790 DOI: 10.1016/J.Brainresbull.2007.05.004 |
0.381 |
|
2007 |
Dhir A, Kulkarni SK. Effect of addition of yohimbine (alpha-2-receptor antagonist) to the antidepressant activity of fluoxetine or venlafaxine in the mouse forced swim test. Pharmacology. 80: 239-43. PMID 17622775 DOI: 10.1159/000104877 |
0.427 |
|
2007 |
Dhir A, Naidu PS, Kulkarni SK. Neuroprotective effect of nimesulide, a preferential COX-2 inhibitor, against pentylenetetrazol (PTZ)-induced chemical kindling and associated biochemical parameters in mice. Seizure. 16: 691-7. PMID 17604186 DOI: 10.1016/J.Seizure.2007.05.016 |
0.445 |
|
2007 |
Kulkarni SK, Dhir A. Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride. European Journal of Pharmacology. 569: 77-83. PMID 17585901 DOI: 10.1016/J.Ejphar.2007.05.002 |
0.421 |
|
2007 |
Kulkarni SK, Dhir A. Effect of various classes of antidepressants in behavioral paradigms of despair. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 1248-54. PMID 17570574 DOI: 10.1016/J.Pnpbp.2007.05.002 |
0.423 |
|
2007 |
Dhir A, Kulkarni SK. Involvement of sigma-1 receptor modulation in the antidepressant action of venlafaxine. Neuroscience Letters. 420: 204-8. PMID 17532136 DOI: 10.1016/J.Neulet.2007.04.055 |
0.432 |
|
2007 |
Dhir A, Kulkarni SK. Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor. European Journal of Pharmacology. 568: 177-85. PMID 17509558 DOI: 10.1016/J.Ejphar.2007.04.028 |
0.438 |
|
2007 |
Dhir A, Kulkarni SK. Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of venlafaxine in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 921-5. PMID 17379375 DOI: 10.1016/J.Pnpbp.2007.02.008 |
0.409 |
|
2006 |
Dhir A, Kulkarni SK. Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor potentiates the anticonvulsant activity of tiagabine against pentylenetetrazol-induced convulsions in mice. Inflammopharmacology. 14: 222-5. PMID 17139446 DOI: 10.1007/S10787-006-1535-3 |
0.509 |
|
2006 |
Dhir A, Naidu PS, Kulkarni SK. Effect of cyclooxygenase inhibitors on pentylenetetrazol (PTZ)-induced convulsions: Possible mechanism of action. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30: 1478-85. PMID 16844276 DOI: 10.1016/J.Pnpbp.2006.06.003 |
0.461 |
|
2006 |
Dhir A, Naidu PS, Kulkarni SK. Effect of rofecoxib, a cyclo-oxygenase-2 inhibitor, on various biochemical parameters of brain associated with pentylenetetrazol-induced chemical kindling in mice. Fundamental & Clinical Pharmacology. 20: 255-61. PMID 16671960 DOI: 10.1111/J.1472-8206.2006.00398.X |
0.468 |
|
2006 |
Dhir A, Naidu PS, Kulkarni SK. Effect of cyclooxygenase-2 (COX-2) inhibitors in various animal models (bicuculline, picrotoxin, maximal electroshock-induced convulsions) of epilepsy with possible mechanism of action. Indian Journal of Experimental Biology. 44: 286-91. PMID 16629370 |
0.391 |
|
2006 |
Deshpande C, Dhir A, Kulkarni SK. Antagonistic activity of ascorbic acid (vitamin C) on dopaminergic modulation: apomorphine-induced stereotypic behavior in mice. Pharmacology. 77: 38-45. PMID 16569938 DOI: 10.1159/000092409 |
0.417 |
|
2006 |
Dhir A, Padi SS, Naidu PS, Kulkarni SK. Protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice. European Journal of Pharmacology. 535: 192-8. PMID 16522321 DOI: 10.1016/J.Ejphar.2006.01.064 |
0.351 |
|
2005 |
Dhir A, Naidu PS, Kulkarni SK. Protective effect of cyclooxygenase-2 (COX-2) inhibitors but not non-selective cyclooxygenase (COX)-inhibitors on ethanol withdrawal-induced behavioural changes. Addiction Biology. 10: 329-35. PMID 16318954 DOI: 10.1080/13556210500352964 |
0.359 |
|
2005 |
Dhir A, Naidu PS, Kulkarni SK. Effect of naproxen, a non-selective cyclo-oxygenase inhibitor, on pentylenetetrazol-induced kindling in mice. Clinical and Experimental Pharmacology & Physiology. 32: 574-84. PMID 16026518 DOI: 10.1111/J.1440-1681.2005.04233.X |
0.485 |
|
2005 |
Dhir A, Naidu PS, Kulkarni SK. Modulatory Effect of Nimesulide on Apomorphine Induced Stereotypy cind MK-801 Induced Hyperlocomotion Annals of Neurosciences. 12: 71-73. DOI: 10.5214/125 |
0.407 |
|
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