Aleksander S. Popel - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering, Molecular Biology, General Biophysics

280 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zhang Y, Kontos CD, Annex BH, Popel AS. A systems biology model of junctional localization and downstream signaling of the Ang-Tie signaling pathway. Npj Systems Biology and Applications. 7: 34. PMID 34417472 DOI: 10.1038/s41540-021-00194-6  1
2021 Gong C, Ruiz-Martinez A, Kimko H, Popel AS. A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor-Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy. Cancers. 13. PMID 34359653 DOI: 10.3390/cancers13153751  1
2021 Zhao C, Medeiros TX, Sové RJ, Annex BH, Popel AS. A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization. Iscience. 24: 102112. PMID 33659877 DOI: 10.1016/j.isci.2021.102112  1
2021 Ma H, Pilvankar M, Wang J, Giragossian C, Popel AS. Quantitative Systems Pharmacology Modeling of PBMC-Humanized Mouse to Facilitate Preclinical Immuno-oncology Drug Development. Acs Pharmacology & Translational Science. 4: 213-225. PMID 33615174 DOI: 10.1021/acsptsci.0c00178  0.04
2021 Wang H, Ma H, Sové RJ, Emens LA, Popel AS. Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer. Journal For Immunotherapy of Cancer. 9. PMID 33579739 DOI: 10.1136/jitc-2020-002100  1
2020 Furukawa N, Popel AS. Therapeutic peptides that immunoactivate the tumor microenvironment. Biochimica Et Biophysica Acta. Reviews On Cancer. 188486. PMID 33276025 DOI: 10.1016/j.bbcan.2020.188486  0.01
2020 Mi H, Gong C, Sulam J, Fertig EJ, Szalay AS, Jaffee EM, Stearns V, Emens LA, Cimino-Mathews AM, Popel AS. Digital Pathology Analysis Quantifies Spatial Heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 Immune Markers in Triple-Negative Breast Cancer. Frontiers in Physiology. 11: 583333. PMID 33192595 DOI: 10.3389/fphys.2020.583333  1
2020 Mirando AC, Patil A, Rafie CI, Christmas BJ, Pandey NB, Stearns V, Jaffee EM, Roussos Torres ET, Popel AS. Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide. Oncoimmunology. 9: 1760685. PMID 32923118 DOI: 10.1080/2162402X.2020.1760685  1
2020 Ma H, Wang H, Sové RJ, Wang J, Giragossian C, Popel AS. Combination therapy with T cell engager and PD-L1 blockade enhances the antitumor potency of T cells as predicted by a QSP model. Journal For Immunotherapy of Cancer. 8. PMID 32859743 DOI: 10.1136/Jitc-2020-001141  1
2020 Mirando AC, Lima E Silva R, Chu Z, Campochiaro PA, Pandey NB, Popel AS. Suppression of Ocular Vascular Inflammation through Peptide-Mediated Activation of Angiopoietin-Tie2 Signaling. International Journal of Molecular Sciences. 21. PMID 32708100 DOI: 10.3390/Ijms21145142  1
2020 Sové RJ, Jafarnejad M, Zhao C, Wang H, Ma H, Popel AS. QSP-IO: A quantitative systems pharmacology toolbox for mechanistic multi-scale modeling for immuno-oncology applications. Cpt: Pharmacometrics & Systems Pharmacology. PMID 32618119 DOI: 10.1002/psp4.12546  1
2020 Ma H, Wang H, Sove RJ, Jafarnejad M, Tsai CH, Wang J, Giragossian C, Popel AS. A Quantitative Systems Pharmacology Model of T Cell Engager Applied to Solid Tumor. The Aaps Journal. 22: 85. PMID 32533270 DOI: 10.1208/S12248-020-00450-3  1
2020 Malone MK, Smrekar K, Park S, Blakely B, Walter A, Nasta N, Park J, Considine M, Danilova LV, Pandey NB, Fertig EJ, Popel AS, Jin K. Cytokines secreted by stromal cells in TNBC microenvironment as potential targets for cancer therapy. Cancer Biology & Therapy. 1-10. PMID 32213106 DOI: 10.1080/15384047.2020.1739484  1
2020 Wang H, Sové RJ, Jafarnejad M, Rahmeh S, Jaffee EM, Stearns V, Torres ETR, Connolly RM, Popel AS. Conducting a Virtual Clinical Trial in HER2-Negative Breast Cancer Using a Quantitative Systems Pharmacology Model With an Epigenetic Modulator and Immune Checkpoint Inhibitors. Frontiers in Bioengineering and Biotechnology. 8: 141. PMID 32158754 DOI: 10.3389/Fbioe.2020.00141  1
2020 Popel AS. Immunoactivating the tumor microenvironment enhances immunotherapy as predicted by integrative computational model. Proceedings of the National Academy of Sciences of the United States of America. 117: 4447-4449. PMID 32102915 DOI: 10.1073/Pnas.2001050117  0.01
2019 Jafarnejad M, Sové RJ, Danilova L, Mirando AC, Zhang Y, Yarchoan M, Tran PT, Pandey NB, Fertig EJ, Popel AS. Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma. Npj Systems Biology and Applications. 5: 29. PMID 32801315 DOI: 10.1038/s41540-019-0107-2  1
2019 Zhao C, Mirando AC, Sové RJ, Medeiros TX, Annex BH, Popel AS. A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology. Plos Computational Biology. 15: e1007468. PMID 31738746 DOI: 10.1371/Journal.Pcbi.1007468  1
2019 Zhang Y, Kontos CD, Annex BH, Popel AS. Angiopoietin-Tie Signaling Pathway in Endothelial Cells: A Computational Model. Iscience. 20: 497-511. PMID 31655061 DOI: 10.1016/J.Isci.2019.10.006  1
2019 Jafarnejad M, Sové RJ, Danilova L, Mirando AC, Zhang Y, Yarchoan M, Tran PT, Pandey NB, Fertig EJ, Popel AS. Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma. Npj Systems Biology and Applications. 5: 29. PMID 31452933 DOI: 10.1038/s41540-019-0107-2  1
2019 Milberg O, Gong C, Jafarnejad M, Bartelink IH, Wang B, Vicini P, Narwal R, Roskos L, Popel AS. A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade. Scientific Reports. 9: 11286. PMID 31375756 DOI: 10.1038/S41598-019-47802-4  1
2019 Kim J, Lima E Silva R, Shmueli RB, Mirando AC, Tzeng SY, Pandey NB, Ben-Akiva E, Popel AS, Campochiaro PA, Green JJ. Anisotropic poly(lactic-co-glycolic acid) microparticles enable sustained release of a peptide for long-term inhibition of ocular neovascularization. Acta Biomaterialia. PMID 31374338 DOI: 10.1016/J.Actbio.2019.07.054  1
2019 Jafarnejad M, Gong C, Gabrielson E, Bartelink IH, Vicini P, Wang B, Narwal R, Roskos L, Popel AS. A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer. The Aaps Journal. 21: 79. PMID 31236847 DOI: 10.1208/S12248-019-0350-X  1
2019 Wang H, Milberg O, Bartelink IH, Vicini P, Wang B, Narwal R, Roskos L, Santa-Maria CA, Popel AS. simulation of a clinical trial with anti-CTLA-4 and anti-PD-L1 immunotherapies in metastatic breast cancer using a systems pharmacology model. Royal Society Open Science. 6: 190366. PMID 31218069 DOI: 10.1098/Rsos.190366  1
2019 Stamatelos SK, Bhargava A, Kim E, Popel AS, Pathak AP. Tumor Ensemble-Based Modeling and Visualization of Emergent Angiogenic Heterogeneity in Breast Cancer. Scientific Reports. 9: 5276. PMID 30918274 DOI: 10.1038/S41598-019-40888-W  1
2019 Gkontra P, El-Bouri WK, Norton KA, Santos A, Popel AS, Payne SJ, Arroyo AG. Dynamic Changes in Microvascular Flow Conductivity and Perfusion After Myocardial Infarction Shown by Image-Based Modeling. Journal of the American Heart Association. 8: e011058. PMID 30897998 DOI: 10.1161/Jaha.118.011058  1
2019 Norton KA, Gong C, Jamalian S, Popel AS. Multiscale Agent-Based and Hybrid Modeling of the Tumor Immune Microenvironment. Processes (Basel, Switzerland). 7. PMID 30701168 DOI: 10.3390/pr7010037  1
2019 Zhao C, Zhang Y, Popel AS. Mechanistic Computational Models of MicroRNA-Mediated Signaling Networks in Human Diseases. International Journal of Molecular Sciences. 20. PMID 30669429 DOI: 10.3390/Ijms20020421  1
2019 Mirando AC, Shen J, Lima E Silva R, Chu Z, Sass N, Lorenc VE, Green JJ, Campochiaro PA, Popel AS, Pandey NB. A collagen IV-derived peptide disrupts α5β1 integrin and potentiates Ang2-Tie2 signaling. Jci Insight. PMID 30668550 DOI: 10.1172/Jci.Insight.122043  1
2018 Gong C, Anders RA, Zhu Q, Taube JM, Green B, Cheng W, Bartelink IH, Vicini P, Wang B, Popel AS. Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors. Frontiers in Oncology. 8: 649. PMID 30666298 DOI: 10.3389/Fonc.2018.00649  1
2018 Zhang Y, Bazzazi H, Lima E Silva R, Pandey NB, Green JJ, Campochiaro PA, Popel AS. Three-Dimensional Transport Model for Intravitreal and Suprachoroidal Drug Injection. Investigative Ophthalmology & Visual Science. 59: 5266-5276. PMID 30383198 DOI: 10.1167/Iovs.17-23632  1
2018 Gkontra P, Norton KA, Żak MM, Clemente C, Agüero J, Ibáñez B, Santos A, Popel AS, Arroyo AG. Author Correction: Deciphering microvascular changes after myocardial infarction through 3D fully automated image analysis. Scientific Reports. 8: 14563. PMID 30254337 DOI: 10.1038/S41598-018-32598-6  1
2018 Bazzazi H, Zhang Y, Jafarnejad M, Popel AS. Computational modeling of synergistic interaction between αVβ3 integrin and VEGFR2 in endothelial cells: implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides. Journal of Theoretical Biology. PMID 30036530 DOI: 10.1016/J.Jtbi.2018.06.029  1
2018 Bazzazi H, Zhang Y, Jafarnejad M, Isenberg JS, Annex BH, Popel AS. Computer Simulation of TSP1 Inhibition of VEGF-Akt-eNOS: An Angiogenesis Triple Threat. Frontiers in Physiology. 9: 644. PMID 29899706 DOI: 10.3389/Fphys.2018.00644  1
2018 Jin K, Pandey NB, Popel AS. Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis. Breast Cancer Research : Bcr. 20: 54. PMID 29898755 DOI: 10.1186/S13058-018-0981-3  1
2018 Norton KA, Jin K, Popel AS. Modeling triple-negative breast cancer heterogeneity: effects of stromal macrophages, fibroblasts and tumor vasculature. Journal of Theoretical Biology. PMID 29750999 DOI: 10.1016/J.Jtbi.2018.05.003  1
2018 Zhao C, Isenberg JS, Popel AS. Human expression patterns: qualitative and quantitative analysis of thrombospondin-1 under physiological and pathological conditions. Journal of Cellular and Molecular Medicine. PMID 29441713 DOI: 10.1111/Jcmm.13565  1
2018 Bressler EM, Kim J, Shmueli RB, Mirando AC, Bazzazi H, Lee E, Popel AS, Pandey NB, Green JJ. Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells. Journal of Biomedical Materials Research. Part A. PMID 29424479 DOI: 10.1002/Jbm.A.36360  1
2018 Gkontra P, Norton KA, Żak MM, Clemente C, Agüero J, Ibáñez B, Santos A, Popel AS, Arroyo AG. Deciphering microvascular changes after myocardial infarction through 3D fully automated image analysis. Scientific Reports. 8: 1854. PMID 29382844 DOI: 10.1038/S41598-018-19758-4  1
2017 Barbhuiya MA, Mirando AC, Simons BW, Lemtiri-Chlieh G, Green JJ, Popel AS, Pandey NB, Tran PT. Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma. Oncotarget. 8: 101520-101534. PMID 29254183 DOI: 10.18632/Oncotarget.21148  1
2017 Jin K, Pandey NB, Popel AS. Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis. Oncotarget. 8: 60210-60222. PMID 28947965 DOI: 10.18632/Oncotarget.19417  1
2017 Gong C, Milberg O, Wang B, Vicini P, Narwal R, Roskos L, Popel AS. A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition. Journal of the Royal Society, Interface. 14. PMID 28931635 DOI: 10.1098/Rsif.2017.0320  1
2017 Jin K, Pandey NB, Popel AS. Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis. Oncotarget. PMID 28753581 DOI: 10.18632/oncotarget.19417  1
2017 Norton KA, Wallace T, Pandey NB, Popel AS. An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia. Bmc Systems Biology. 11: 68. PMID 28693495 DOI: 10.1186/S12918-017-0445-X  1
2017 Bazzazi H, Isenberg JS, Popel AS. Corrigendum: Inhibition of VEGFR2 Activation and Its Downstream Signaling to ERK1/2 and Calcium by Thrombospondin-1 (TSP1): In silico Investigation. Frontiers in Physiology. 8: 147. PMID 28275355 DOI: 10.3389/Fphys.2017.00147  1
2017 Bazzazi H, Isenberg JS, Popel AS. Inhibition of VEGFR2 Activation and Its Downstream Signaling to ERK1/2 and Calcium by Thrombospondin-1 (TSP1): In silico Investigation. Frontiers in Physiology. 8: 48. PMID 28220078 DOI: 10.3389/Fphys.2017.00048  1
2017 Bazzazi H, Popel AS. Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells. Plos Computational Biology. 13: e1005332. PMID 28178265 DOI: 10.1371/Journal.Pcbi.1005332  1
2017 Lima E Silva R, Kanan Y, Mirando AC, Kim J, Shmueli RB, Lorenc VE, Fortmann SD, Sciamanna J, Pandey NB, Green JJ, Popel AS, Campochiaro PA. Tyrosine kinase blocking collagen IV-derived peptide suppresses ocular neovascularization and vascular leakage. Science Translational Medicine. 9. PMID 28100839 DOI: 10.1126/Scitranslmed.Aai8030  1
2017 Zhao C, Isenberg JS, Popel AS. Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model. Plos Computational Biology. 13: e1005272. PMID 28045898 DOI: 10.1371/Journal.Pcbi.1005272  1
2017 Gong C, Milberg O, Wang B, Vicini P, Narwal R, Roskos L, Popel AS. Abstract 975: A multiscale computational model for spatio-temporal tumor immune response Cancer Research. 77: 975-975. DOI: 10.1158/1538-7445.Am2017-975  1
2017 Jin K, Pandey NB, Popel AS. Abstract 5896: IL-8 signaling enhances TNBC growth and metastasis via crosstalk with stromal components Cancer Research. 77: 5896-5896. DOI: 10.1158/1538-7445.Am2017-5896  1
2017 Milberg O, Gong C, Wang B, Vicini P, Narwal R, Roskos L, Popel A. Abstract 4531: Systems pharmacology to predict cellular biomarkers and optimize mono- and combination-therapy regimens: Focusing on immune checkpoint targets PD-1, PD-L1 and CTLA-4 Cancer Research. 77: 4531-4531. DOI: 10.1158/1538-7445.Am2017-4531  0.04
2017 Barbhuiya MA, Mirando AC, Simons BW, Lemtiri-Chlieh G, Green JJ, Popel AS, Pandey NB, Tran PT. Abstract 3201: Therapeutic potential of anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma Cancer Research. 77: 3201-3201. DOI: 10.1158/1538-7445.Am2017-3201  1
2016 Dore-Savard L, Lee E, Kakkad S, Popel AS, Bhujwalla ZM. The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts. Scientific Reports. 6: 39460. PMID 27995973 DOI: 10.1038/Srep39460  1
2016 Kim J, Mirando AC, Popel AS, Green JJ. Gene delivery nanoparticles to modulate angiogenesis. Advanced Drug Delivery Reviews. PMID 27913120 DOI: 10.1016/J.Addr.2016.11.003  1
2016 Chu LH, Ganta VC, Choi MH, Chen G, Finley SD, Annex BH, Popel AS. A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF165b in peripheral arterial disease in human and mouse. Scientific Reports. 6: 37030. PMID 27853189 DOI: 10.1038/Srep37030  1
2016 Norton KA, Popel AS. Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis. Scientific Reports. 6: 36992. PMID 27841344 DOI: 10.1038/Srep36992  1
2016 Yankeelov TE, An G, Saut O, Luebeck EG, Popel AS, Ribba B, Vicini P, Zhou X, Weis JA, Ye K, Genin GM. Multi-scale Modeling in Clinical Oncology: Opportunities and Barriers to Success. Annals of Biomedical Engineering. PMID 27384942 DOI: 10.1007/S10439-016-1691-6  1
2016 Noren DP, Chou WH, Lee SH, Qutub AA, Warmflash A, Wagner DS, Popel AS, Levchenko A. Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses. Science Signaling. 9: ra20. PMID 26905425 DOI: 10.1126/Scisignal.Aad3188  0.56
2016 Clancy CE, An G, Cannon WR, Liu Y, May EE, Ortoleva P, Popel AS, Sluka JP, Su J, Vicini P, Zhou X, Eckmann DM. Multiscale Modeling in the Clinic: Drug Design and Development. Annals of Biomedical Engineering. PMID 26885640 DOI: 10.1007/S10439-016-1563-0  1
2016 Jin K, Pandey NB, Popel AS. Abstract 4084: Crosstalk between TNBC and stromal components via secreted factors enhances cell motility that can be attenuated by a CXCR1 inhibitor Cancer Research. 76: 4084-4084. DOI: 10.1158/1538-7445.Am2016-4084  1
2016 Dore-Savard L, Bharti SK, Popel AS, Bhujwalla ZM. Abstract 3370: Metabolic profiling of the tumor interstitial fluid using 1H MRS: contribution of breast cancer subtypes and VEGF overexpression Cancer Research. 76: 3370-3370. DOI: 10.1158/1538-7445.Am2016-3370  1
2015 Zhao C, Popel AS. Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer. Plos Computational Biology. 11: e1004612. PMID 26588727 DOI: 10.1371/Journal.Pcbi.1004612  1
2015 Chu LH, Annex BH, Popel AS. Computational drug repositioning for peripheral arterial disease: prediction of anti-inflammatory and pro-angiogenic therapeutics. Frontiers in Pharmacology. 6: 179. PMID 26379552 DOI: 10.3389/Fphar.2015.00179  1
2015 Fertig EJ, Lee E, Pandey NB, Popel AS. Analysis of gene expression of secreted factors associated with breast cancer metastases in breast cancer subtypes. Scientific Reports. 5: 12133. PMID 26173622 DOI: 10.1038/Srep12133  1
2015 Norton KA, Popel AS, Pandey NB. Heterogeneity of chemokine cell-surface receptor expression in triple-negative breast cancer. American Journal of Cancer Research. 5: 1295-307. PMID 26101698  1
2015 Chu LH, Vijay CG, Annex BH, Bader JS, Popel AS. PADPIN: protein-protein interaction networks of angiogenesis, arteriogenesis, and inflammation in peripheral arterial disease. Physiological Genomics. 47: 331-43. PMID 26058837 DOI: 10.1152/Physiolgenomics.00125.2014  1
2015 Lee E, Pandey NB, Popel AS. Crosstalk between cancer cells and blood endothelial and lymphatic endothelial cells in tumour and organ microenvironment. Expert Reviews in Molecular Medicine. 17: e3. PMID 25634527 DOI: 10.1017/Erm.2015.2  1
2015 Kim E, Lee E, Plummer C, Gil S, Popel AS, Pathak AP. Vasculature-specific MRI reveals differential anti-angiogenic effects of a biomimetic peptide in an orthotopic breast cancer model. Angiogenesis. 18: 125-36. PMID 25408417 DOI: 10.1007/S10456-014-9450-5  1
2015 Finley SD, Chu LH, Popel AS. Computational systems biology approaches to anti-angiogenic cancer therapeutics. Drug Discovery Today. 20: 187-97. PMID 25286370 DOI: 10.1016/J.Drudis.2014.09.026  1
2015 Dore-Savard L, Lee E, Popel AS, Bhujwalla ZM. Abstract 4172: Differential angiogenesis-related cytokines release in tumor interstitial fluid and plasma in ER-positive and triple-negative breast cancers overexpressing VEGF Cancer Research. 75: 4172-4172. DOI: 10.1158/1538-7445.Am2015-4172  1
2015 Gkontra P, Żak MM, Norton KA, Santos A, Popel AS, Arroyo AG. A 3D fractal-based approach towards understanding changes in the infarcted heart microvasculature Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9351: 173-180. DOI: 10.1007/978-3-319-24574-4_21  1
2015 Finley SD, Angelikopoulos P, Koumoutsakos P, Popel AS. Pharmacokinetics of Anti-VEGF Agent aflibercept in cancer predicted by data-driven, molecular-detailed model Cpt: Pharmacometrics and Systems Pharmacology. 4: 641-649. DOI: 10.1002/psp4.12040  1
2014 Lee E, Lee SJ, Koskimaki JE, Han Z, Pandey NB, Popel AS. Inhibition of breast cancer growth and metastasis by a biomimetic peptide. Scientific Reports. 4: 7139. PMID 25409905 DOI: 10.1038/Srep07139  1
2014 Rosca EV, Penet MF, Mori N, Koskimaki JE, Lee E, Pandey NB, Bhujwalla ZM, Popel AS. A biomimetic collagen derived peptide exhibits anti-angiogenic activity in triple negative breast cancer. Plos One. 9: e111901. PMID 25384034 DOI: 10.1371/Journal.Pone.0111901  1
2014 Chu LH, Lee E, Bader JS, Popel AS. Angiogenesis interactome and time course microarray data reveal the distinct activation patterns in endothelial cells. Plos One. 9: e110871. PMID 25329517 DOI: 10.1371/Journal.Pone.0110871  1
2014 Norton KA, Han Z, Popel AS, Pandey NB. Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells. Oncotargets and Therapy. 7: 1571-82. PMID 25228815 DOI: 10.2147/Ott.S65055  1
2014 Norton KA, Popel AS. An agent-based model of cancer stem cell initiated avascular tumour growth and metastasis: the effect of seeding frequency and location. Journal of the Royal Society, Interface / the Royal Society. 11: 20140640. PMID 25185580 DOI: 10.1098/Rsif.2014.0640  1
2014 Lee E, Fertig EJ, Jin K, Sukumar S, Pandey NB, Popel AS. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nature Communications. 5: 4715. PMID 25178650 DOI: 10.1038/Ncomms5715  1
2014 Lee E, Pandey NB, Popel AS. Lymphatic endothelial cells support tumor growth in breast cancer. Scientific Reports. 4: 5853. PMID 25068296 DOI: 10.1038/Srep05853  1
2014 Imoukhuede PI, Popel AS. Quantitative fluorescent profiling of VEGFRs reveals tumor cell and endothelial cell heterogeneity in breast cancer xenografts. Cancer Medicine. 3: 225-44. PMID 24449499 DOI: 10.1002/Cam4.188  1
2014 Stamatelos SK, Kim E, Pathak AP, Popel AS. A bioimage informatics based reconstruction of breast tumor microvasculature with computational blood flow predictions. Microvascular Research. 91: 8-21. PMID 24342178 DOI: 10.1016/J.Mvr.2013.12.003  1
2014 Vempati P, Popel AS, Mac Gabhann F. Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning. Cytokine & Growth Factor Reviews. 25: 1-19. PMID 24332926 DOI: 10.1016/J.Cytogfr.2013.11.002  1
2014 Logsdon EA, Finley SD, Popel AS, Mac Gabhann F. A systems biology view of blood vessel growth and remodelling. Journal of Cellular and Molecular Medicine. 18: 1491-508. PMID 24237862 DOI: 10.1111/Jcmm.12164  1
2014 Lee E, Pandey NB, Popel AS. Pre-treatment of mice with tumor-conditioned media accelerates metastasis to lymph nodes and lungs: a new spontaneous breast cancer metastasis model. Clinical & Experimental Metastasis. 31: 67-79. PMID 23963763 DOI: 10.1007/S10585-013-9610-9  1
2014 Dore-Savard L, Lee E, Popel AS, Bhujwalla ZM. Abstract 3001: Angiogenesis-related cytokine secretion pattern in tumor interstitial fluid and its relationship with VEGF expression and metastatic profile Cancer Research. 74: 3001-3001. DOI: 10.1158/1538-7445.Am2014-3001  1
2013 Tan WH, Popel AS, Mac Gabhann F. Computational model of VEGFR2 pathway to ERK activation and modulation through receptor trafficking. Cellular Signalling. 25: 2496-510. PMID 23993967 DOI: 10.1016/J.Cellsig.2013.08.015  1
2013 Finley SD, Dhar M, Popel AS. Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice. Frontiers in Oncology. 3: 196. PMID 23908970 DOI: 10.3389/Fonc.2013.00196  1
2013 Shmueli RB, Ohnaka M, Miki A, Pandey NB, Lima e Silva R, Koskimaki JE, Kim J, Popel AS, Campochiaro PA, Green JJ. Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide. Biomaterials. 34: 7544-51. PMID 23849876 DOI: 10.1016/J.Biomaterials.2013.06.044  1
2013 Tan WH, Popel AS, Mac Gabhann F. Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation. Plos One. 8: e67438. PMID 23805312 DOI: 10.1371/Journal.Pone.0067438  1
2013 Finley SD, Popel AS. Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions. Journal of the National Cancer Institute. 105: 802-11. PMID 23670728 DOI: 10.1093/Jnci/Djt093  1
2013 Lee E, Koskimaki JE, Pandey NB, Popel AS. Inhibition of lymphangiogenesis and angiogenesis in breast tumor xenografts and lymph nodes by a peptide derived from transmembrane protein 45A. Neoplasia (New York, N.Y.). 15: 112-24. PMID 23441126 DOI: 10.1593/Neo.121638  1
2013 Imoukhuede PI, Dokun AO, Annex BH, Popel AS. Endothelial cell-by-cell profiling reveals the temporal dynamics of VEGFR1 and VEGFR2 membrane localization after murine hindlimb ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1085-93. PMID 23376830 DOI: 10.1152/Ajpheart.00514.2012  1
2013 Koskimaki JE, Lee E, Chen W, Rivera CG, Rosca EV, Pandey NB, Popel AS. Synergy between a collagen IV mimetic peptide and a somatotropin-domain derived peptide as angiogenesis and lymphangiogenesis inhibitors. Angiogenesis. 16: 159-70. PMID 23053781 DOI: 10.1007/S10456-012-9308-7  1
2013 Lee E, Pandey N, Popel A. Abstract B27: Lymphatic endothelium promotes angiogenesis, tumor growth, and metastasis in breast cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-B27  1
2012 Liu G, Mac Gabhann F, Popel AS. Effects of fiber type and size on the heterogeneity of oxygen distribution in exercising skeletal muscle. Plos One. 7: e44375. PMID 23028531 DOI: 10.1371/Journal.Pone.0044375  1
2012 Imoukhuede PI, Popel AS. Expression of VEGF receptors on endothelial cells in mouse skeletal muscle. Plos One. 7: e44791. PMID 22984559 DOI: 10.1371/Journal.Pone.0044791  1
2012 Chu LH, Rivera CG, Popel AS, Bader JS. Constructing the angiome: a global angiogenesis protein interaction network. Physiological Genomics. 44: 915-24. PMID 22911453 DOI: 10.1152/Physiolgenomics.00181.2011  1
2012 Kim E, Stamatelos S, Cebulla J, Bhujwalla ZM, Popel AS, Pathak AP. Multiscale imaging and computational modeling of blood flow in the tumor vasculature. Annals of Biomedical Engineering. 40: 2425-41. PMID 22565817 DOI: 10.1007/S10439-012-0585-5  1
2012 Finley SD, Popel AS. Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms. The Aaps Journal. 14: 500-9. PMID 22547351 DOI: 10.1208/S12248-012-9363-4  1
2012 Koskimaki JE, Rosca EV, Rivera CG, Lee E, Chen W, Pandey NB, Popel AS. Serpin-derived peptides are antiangiogenic and suppress breast tumor xenograft growth. Translational Oncology. 5: 92-7. PMID 22496925 DOI: 10.1593/Tlo.11244  1
2012 Rosca EV, Lal B, Koskimaki JE, Popel AS, Laterra J. Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth. Anti-Cancer Drugs. 23: 706-12. PMID 22495619 DOI: 10.1097/Cad.0B013E3283531041  1
2012 Li X, Popel AS, Karniadakis GE. Blood-plasma separation in Y-shaped bifurcating microfluidic channels: a dissipative particle dynamics simulation study. Physical Biology. 9: 026010. PMID 22476709 DOI: 10.1088/1478-3975/9/2/026010  1
2012 Rosca EV, Koskimaki JE, Pandey NB, Tamiz AP, Popel AS. Structure-activity relationship study of collagen-derived anti-angiogenic biomimetic peptides. Chemical Biology & Drug Design. 80: 27-37. PMID 22405100 DOI: 10.1111/J.1747-0285.2012.01376.X  1
2012 Stefanini MO, Qutub AA, Mac Gabhann F, Popel AS. Computational models of VEGF-associated angiogenic processes in cancer. Mathematical Medicine and Biology : a Journal of the Ima. 29: 85-94. PMID 21266494 DOI: 10.1093/Imammb/Dqq025  1
2012 Rivera CG, Chu LH, Bader JS, Popel AS. Applications of Network Bioinformatics to Cancer Angiogenesis Systems Biology in Cancer Research and Drug Discovery. 2147483647: 229-244. DOI: 10.1007/978-94-007-4819-4_9  1
2011 Finley SD, Engel-Stefanini MO, Imoukhuede PI, Popel AS. Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies. Bmc Systems Biology. 5: 193. PMID 22104283 DOI: 10.1186/1752-0509-5-193  1
2011 Yen P, Finley SD, Engel-Stefanini MO, Popel AS. A two-compartment model of VEGF distribution in the mouse. Plos One. 6: e27514. PMID 22087332 DOI: 10.1371/Journal.Pone.0027514  1
2011 Rivera CG, Mellberg S, Claesson-Welsh L, Bader JS, Popel AS. Analysis of VEGF--a regulated gene expression in endothelial cells to identify genes linked to angiogenesis. Plos One. 6: e24887. PMID 21931866 DOI: 10.1371/Journal.Pone.0024887  1
2011 Lee E, Rosca EV, Pandey NB, Popel AS. Small peptides derived from somatotropin domain-containing proteins inhibit blood and lymphatic endothelial cell proliferation, migration, adhesion and tube formation. The International Journal of Biochemistry & Cell Biology. 43: 1812-21. PMID 21920451 DOI: 10.1016/J.Biocel.2011.08.020  1
2011 Rosca EV, Koskimaki JE, Pandey NB, Wolff AC, Popel AS. Development of a biomimetic peptide derived from collagen IV with anti-angiogenic activity in breast cancer. Cancer Biology & Therapy. 12: 808-17. PMID 21878750 DOI: 10.4161/Cbt.12.9.17677  1
2011 Rivera CG, Rosca EV, Pandey NB, Koskimaki JE, Bader JS, Popel AS. Novel peptide-specific quantitative structure-activity relationship (QSAR) analysis applied to collagen IV peptides with antiangiogenic activity. Journal of Medicinal Chemistry. 54: 6492-500. PMID 21866962 DOI: 10.1021/Jm200114F  1
2011 Rivera CG, Bader JS, Popel AS. Angiogenesis-associated crosstalk between collagens, CXC chemokines, and thrombospondin domain-containing proteins. Annals of Biomedical Engineering. 39: 2213-22. PMID 21590489 DOI: 10.1007/S10439-011-0325-2  1
2011 Vempati P, Popel AS, Mac Gabhann F. Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis. Bmc Systems Biology. 5: 59. PMID 21535871 DOI: 10.1186/1752-0509-5-59  1
2011 Rosca EV, Koskimaki JE, Rivera CG, Pandey NB, Tamiz AP, Popel AS. Anti-angiogenic peptides for cancer therapeutics. Current Pharmaceutical Biotechnology. 12: 1101-16. PMID 21470139 DOI: 10.2174/138920111796117300  1
2011 Liu G, Qutub AA, Vempati P, Mac Gabhann F, Popel AS. Module-based multiscale simulation of angiogenesis in skeletal muscle. Theoretical Biology & Medical Modelling. 8: 6. PMID 21463529 DOI: 10.1186/1742-4682-8-6  1
2011 Imoukhuede PI, Popel AS. Quantification and cell-to-cell variation of vascular endothelial growth factor receptors. Experimental Cell Research. 317: 955-65. PMID 21185287 DOI: 10.1016/J.Yexcr.2010.12.014  1
2011 Waters SL, Alastruey J, Beard DA, Bovendeerd PH, Davies PF, Jayaraman G, Jensen OE, Lee J, Parker KH, Popel AS, Secomb TW, Siebes M, Sherwin SJ, Shipley RJ, Smith NP, et al. Theoretical models for coronary vascular biomechanics: progress & challenges. Progress in Biophysics and Molecular Biology. 104: 49-76. PMID 21040741 DOI: 10.1016/J.Pbiomolbio.2010.10.001  1
2011 Rosca EV, Penet M, Koskimaki JE, Pandey NB, Bhujwalla ZM, Popel AS. Abstract 4267: Biomimetic anti-angiogenic peptide as therapeutic agent for breast cancer Cancer Research. 71: 4267-4267. DOI: 10.1158/1538-7445.Am2011-4267  1
2010 Stefanini MO, Wu FT, Mac Gabhann F, Popel AS. Increase of plasma VEGF after intravenous administration of bevacizumab is predicted by a pharmacokinetic model. Cancer Research. 70: 9886-94. PMID 21118974 DOI: 10.1158/0008-5472.Can-10-1419  1
2010 Fedosov DA, Caswell B, Popel AS, Karniadakis GE. Blood flow and cell-free layer in microvessels. Microcirculation (New York, N.Y. : 1994). 17: 615-28. PMID 21044216 DOI: 10.1111/J.1549-8719.2010.00056.X  1
2010 Mac Gabhann F, Qutub AA, Annex BH, Popel AS. Systems biology of pro-angiogenic therapies targeting the VEGF system. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 694-707. PMID 20890966 DOI: 10.1002/Wsbm.92  1
2010 Mac Gabhann F, Annex BH, Popel AS. Gene therapy from the perspective of systems biology. Current Opinion in Molecular Therapeutics. 12: 570-7. PMID 20886389  1
2010 Vempati P, Mac Gabhann F, Popel AS. Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model. Plos One. 5: e11860. PMID 20686621 DOI: 10.1371/Journal.Pone.0011860  1
2010 Wu FT, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS. VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model. American Journal of Physiology. Heart and Circulatory Physiology. 298: H2174-91. PMID 20382861 DOI: 10.1152/Ajpheart.00365.2009  1
2010 Koskimaki JE, Karagiannis ED, Tang BC, Hammers H, Watkins DN, Pili R, Popel AS. Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model. Bmc Cancer. 10: 29. PMID 20122172 DOI: 10.1186/1471-2407-10-29  1
2010 Wu FT, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS. A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use. Journal of Cellular and Molecular Medicine. 14: 528-52. PMID 19840194 DOI: 10.1111/J.1582-4934.2009.00941.X  1
2010 Rosca EV, Koskimaki JE, Popel AS. Abstract 1365: Novel anti-angiogenic peptides as potential therapeutic agents in combination with chemotherapy for breast cancer Cancer Research. 70: 1365-1365. DOI: 10.1158/1538-7445.Am10-1365  1
2009 Popel AS, Hunter PJ. Systems biology and physiome projects. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 1: 153-8. PMID 20835988 DOI: 10.1002/Wsbm.67  1
2009 Stefanini MO, Wu FT, Mac Gabhann F, Popel AS. The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling. Plos Computational Biology. 5: e1000622. PMID 20041209 DOI: 10.1371/Journal.Pcbi.1000622  1
2009 Koskimaki JE, Karagiannis ED, Rosca EV, Vesuna F, Winnard PT, Raman V, Bhujwalla ZM, Popel AS. Peptides derived from type IV collagen, CXC chemokines, and thrombospondin-1 domain-containing proteins inhibit neovascularization and suppress tumor growth in MDA-MB-231 breast cancer xenografts. Neoplasia (New York, N.Y.). 11: 1285-91. PMID 20019836 DOI: 10.1593/Neo.09620  1
2009 Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA. Computational analysis of the tether-pulling experiment to probe plasma membrane-cytoskeleton interaction in cells. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 80: 041905. PMID 19905340 DOI: 10.1103/Physreve.80.041905  1
2009 Wu FT, Stefanini MO, Mac Gabhann F, Popel AS. Modeling of growth factor-receptor systems from molecular-level protein interaction networks to whole-body compartment models. Methods in Enzymology. 467: 461-97. PMID 19897104 DOI: 10.1016/S0076-6879(09)67018-X  1
2009 Chung B, Kim S, Johnson PC, Popel AS. Computational fluid dynamics of aggregating red blood cells in postcapillary venules. Computer Methods in Biomechanics and Biomedical Engineering. 12: 385-97. PMID 19675976 DOI: 10.1080/10255840802624718  1
2009 Chen K, Popel AS. Nitric oxide production pathways in erythrocytes and plasma. Biorheology. 46: 107-19. PMID 19458414 DOI: 10.3233/Bir-2009-0531  1
2009 Wu FT, Stefanini MO, Mac Gabhann F, Popel AS. A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap. Plos One. 4: e5108. PMID 19352513 DOI: 10.1371/Journal.Pone.0005108  1
2009 Wu FT, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS. Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport. Physiological Genomics. 38: 29-41. PMID 19351908 DOI: 10.1152/Physiolgenomics.00031.2009  1
2009 Qutub AA, Mac Gabhann F, Karagiannis ED, Vempati P, Popel AS. Multiscale models of angiogenesis. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 28: 14-31. PMID 19349248 DOI: 10.1109/Memb.2009.931791  1
2009 Zhang J, Johnson PC, Popel AS. Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows. Microvascular Research. 77: 265-72. PMID 19323969 DOI: 10.1016/J.Mvr.2009.01.010  1
2009 Chen K, Pittman RN, Popel AS. Hemorrhagic shock and nitric oxide release from erythrocytic nitric oxide synthase: a quantitative analysis. Microvascular Research. 78: 107-18. PMID 19285090 DOI: 10.1016/J.Mvr.2009.02.009  1
2009 Cano Mdel V, Karagiannis ED, Soliman M, Bakir B, Zhuang W, Popel AS, Gehlbach PL. A peptide derived from type 1 thrombospondin repeat-containing protein WISP-1 inhibits corneal and choroidal neovascularization. Investigative Ophthalmology & Visual Science. 50: 3840-5. PMID 19279315 DOI: 10.1167/Iovs.08-2607  1
2009 Qutub AA, Liu G, Vempati P, Popel AS. Integration of angiogenesis modules at multiple scales: from molecular to tissue. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 316-27. PMID 19209711  1
2009 Qutub AA, Popel AS. Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting. Bmc Systems Biology. 3: 13. PMID 19171061 DOI: 10.1186/1752-0509-3-13  1
2009 Schumacher K, Popel A, Anvari B, Brownell W, Spector A. Computational analysis of the tether pulling experiment to probe cellular membranes Proceedings of the Asme Summer Bioengineering Conference 2009, Sbc2009. 551-552. DOI: 10.1115/SBC2009-206324  1
2008 Karagiannis ED, Popel AS. A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 13775-80. PMID 18780781 DOI: 10.1073/Pnas.0803241105  1
2008 Stefanini MO, Wu FT, Mac Gabhann F, Popel AS. A compartment model of VEGF distribution in blood, healthy and diseased tissues. Bmc Systems Biology. 2: 77. PMID 18713470 DOI: 10.1186/1752-0509-2-77  1
2008 Mac Gabhann F, Popel AS. Systems biology of vascular endothelial growth factors. Microcirculation (New York, N.Y. : 1994). 15: 715-38. PMID 18608994 DOI: 10.1080/10739680802095964  1
2008 Qutub AA, Popel AS. Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. Molecular and Cellular Biology. 28: 5106-19. PMID 18559422 DOI: 10.1128/Mcb.00060-08  1
2008 Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA. Modeling the mechanics of tethers pulled from the cochlear outer hair cell membrane. Journal of Biomechanical Engineering. 130: 031007. PMID 18532856 DOI: 10.1115/1.2907758  1
2008 Sharan M, Vovenko EP, Vadapalli A, Popel AS, Pittman RN. Experimental and theoretical studies of oxygen gradients in rat pial microvessels. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1597-604. PMID 18506196 DOI: 10.1038/Jcbfm.2008.51  1
2008 Demetriades AM, Deering T, Liu H, Lu L, Gehlbach P, Packer JD, Mac Gabhann F, Popel AS, Wei LL, Campochiaro PA. Trans-scleral delivery of antiangiogenic proteins. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 24: 70-9. PMID 18370877 DOI: 10.1089/Jop.2007.0061  1
2008 Chen K, Pittman RN, Popel AS. Nitric oxide in the vasculature: where does it come from and where does it go? A quantitative perspective. Antioxidants & Redox Signaling. 10: 1185-98. PMID 18331202 DOI: 10.1089/Ars.2007.1959  1
2008 Karagiannis ED, Popel AS. Novel anti-angiogenic peptides derived from ELR-containing CXC chemokines. Journal of Cellular Biochemistry. 104: 1356-63. PMID 18307172 DOI: 10.1002/Jcb.21712  1
2008 Chen K, Piknova B, Pittman RN, Schechter AN, Popel AS. Nitric oxide from nitrite reduction by hemoglobin in the plasma and erythrocytes. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 18: 47-60. PMID 17964300 DOI: 10.1016/J.Niox.2007.09.088  1
2008 Zhang J, Johnson PC, Popel AS. Red blood cell aggregation and dissociation in shear flows simulated by lattice Boltzmann method. Journal of Biomechanics. 41: 47-55. PMID 17888442 DOI: 10.1016/J.Jbiomech.2007.07.020  1
2007 Chung B, Johnson PC, Popel AS. Application of Chimera grid to modelling cell motion and aggregation in a narrow tube. International Journal For Numerical Methods in Fluids. 53: 105-128. PMID 29353951 DOI: 10.1002/Fld.1251  1
2007 Zhang J, Johnson PC, Popel AS. An immersed boundary lattice Boltzmann approach to simulate deformable liquid capsules and its application to microscopic blood flows. Physical Biology. 4: 285-95. PMID 18185006 DOI: 10.1088/1478-3975/4/4/005  1
2007 Kut C, Mac Gabhann F, Popel AS. Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer. British Journal of Cancer. 97: 978-85. PMID 17912242 DOI: 10.1038/Sj.Bjc.6603923  1
2007 Liao Z, Feng S, Popel AS, Brownell WE, Spector AA. Outer hair cell active force generation in the cochlear environment. The Journal of the Acoustical Society of America. 122: 2215-25. PMID 17902857 DOI: 10.1121/1.2776154  1
2007 Ji JW, Mac Gabhann F, Popel AS. Skeletal muscle VEGF gradients in peripheral arterial disease: simulations of rest and exercise. American Journal of Physiology. Heart and Circulatory Physiology. 293: H3740-9. PMID 17890434 DOI: 10.1152/Ajpheart.00009.2007  1
2007 Vempati P, Karagiannis ED, Popel AS. A biochemical model of matrix metalloproteinase 9 activation and inhibition. The Journal of Biological Chemistry. 282: 37585-96. PMID 17848556 DOI: 10.1074/Jbc.M611500200  1
2007 Hazarika S, Dokun AO, Li Y, Popel AS, Kontos CD, Annex BH. Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1. Circulation Research. 101: 948-56. PMID 17823371 DOI: 10.1161/Circresaha.107.160630  1
2007 Qutub AA, Popel AS. Three autocrine feedback loops determine HIF1 alpha expression in chronic hypoxia. Biochimica Et Biophysica Acta. 1773: 1511-25. PMID 17720260 DOI: 10.1016/J.Bbamcr.2007.07.004  1
2007 Karagiannis ED, Popel AS. Peptides derived from type I thrombospondin repeat-containing proteins of the CCN family inhibit proliferation and migration of endothelial cells. The International Journal of Biochemistry & Cell Biology. 39: 2314-23. PMID 17707681 DOI: 10.1016/J.Biocel.2007.06.018  1
2007 Tsoukias NM, Goldman D, Vadapalli A, Pittman RN, Popel AS. A computational model of oxygen delivery by hemoglobin-based oxygen carriers in three-dimensional microvascular networks. Journal of Theoretical Biology. 248: 657-74. PMID 17686494 DOI: 10.1016/J.Jtbi.2007.06.012  1
2007 Kim S, Zhen J, Popel AS, Intaglietta M, Johnson PC. Contributions of collision rate and collision efficiency to erythrocyte aggregation in postcapillary venules at low flow rates. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1947-54. PMID 17616741 DOI: 10.1152/Ajpheart.00764.2006  1
2007 Chen K, Pittman RN, Popel AS. Vascular smooth muscle NO exposure from intraerythrocytic SNOHb: a mathematical model. Antioxidants & Redox Signaling. 9: 1097-110. PMID 17536957 DOI: 10.1089/Ars.2007.1594  1
2007 Karagiannis ED, Popel AS. Anti-angiogenic peptides identified in thrombospondin type I domains. Biochemical and Biophysical Research Communications. 359: 63-9. PMID 17531201 DOI: 10.1016/J.Bbrc.2007.05.041  1
2007 Kim S, Kong RL, Popel AS, Intaglietta M, Johnson PC. Temporal and spatial variations of cell-free layer width in arterioles. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1526-35. PMID 17526647 DOI: 10.1152/Ajpheart.01090.2006  1
2007 Mac Gabhann F, Popel AS. Dimerization of VEGF receptors and implications for signal transduction: a computational study. Biophysical Chemistry. 128: 125-39. PMID 17442480 DOI: 10.1016/J.Bpc.2007.03.010  1
2007 Mac Gabhann F, Ji JW, Popel AS. Multi-scale computational models of pro-angiogenic treatments in peripheral arterial disease. Annals of Biomedical Engineering. 35: 982-94. PMID 17436110 DOI: 10.1007/S10439-007-9303-0  1
2007 Zhi M, Ratnanather JT, Ceyhan E, Popel AS, Brownell WE. Hypotonic swelling of salicylate-treated cochlear outer hair cells. Hearing Research. 228: 95-104. PMID 17400411 DOI: 10.1016/J.Heares.2007.02.007  1
2007 Das B, Bishop JJ, Kim S, Meiselman HJ, Johnson PC, Popel AS. Red blood cell velocity profiles in skeletal muscle venules at low flow rates are described by the Casson model. Clinical Hemorheology and Microcirculation. 36: 217-33. PMID 17361024  1
2007 Chen K, Popel AS. Vascular and perivascular nitric oxide release and transport: biochemical pathways of neuronal nitric oxide synthase (NOS1) and endothelial nitric oxide synthase (NOS3). Free Radical Biology & Medicine. 42: 811-22. PMID 17320763 DOI: 10.1016/J.Freeradbiomed.2006.12.007  1
2007 Mac Gabhann F, Demetriades AM, Deering T, Packer JD, Shah SM, Duh E, Campochiaro PA, Popel AS. Protein transport to choroid and retina following periocular injection: theoretical and experimental study. Annals of Biomedical Engineering. 35: 615-30. PMID 17277991 DOI: 10.1007/S10439-006-9238-X  1
2007 Karagiannis ED, Popel AS. Identification of novel short peptides derived from the alpha 4, alpha 5, and alpha 6 fibrils of type IV collagen with anti-angiogenic properties. Biochemical and Biophysical Research Communications. 354: 434-9. PMID 17239819 DOI: 10.1016/J.Bbrc.2006.12.231  1
2007 Mac Gabhann F, Ji JW, Popel AS. VEGF gradients, receptor activation, and sprout guidance in resting and exercising skeletal muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 102: 722-34. PMID 17038488 DOI: 10.1152/Japplphysiol.00800.2006  1
2007 Mac Gabhann F, Popel AS. Interactions of VEGF isoforms with VEGFR-1, VEGFR-2, and neuropilin in vivo: a computational model of human skeletal muscle. American Journal of Physiology. Heart and Circulatory Physiology. 292: H459-74. PMID 16980341 DOI: 10.1152/Ajpheart.00637.2006  1
2006 Mac Gabhann F, Popel AS. Targeting neuropilin-1 to inhibit VEGF signaling in cancer: Comparison of therapeutic approaches. Plos Computational Biology. 2: e180. PMID 17196035 DOI: 10.1371/Journal.Pcbi.0020180  1
2006 Mac Gabhann F, Ji JW, Popel AS. Computational model of vascular endothelial growth factor spatial distribution in muscle and pro-angiogenic cell therapy. Plos Computational Biology. 2: e127. PMID 17002494 DOI: 10.1371/Journal.Pcbi.0020127  1
2006 Qutub AA, Popel AS. A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha. Journal of Cell Science. 119: 3467-80. PMID 16899821 DOI: 10.1242/Jcs.03087  1
2006 Chen K, Popel AS. Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells. Free Radical Biology & Medicine. 41: 668-80. PMID 16864000 DOI: 10.1016/J.Freeradbiomed.2006.05.009  1
2006 Kim S, Kong RL, Popel AS, Intaglietta M, Johnson PC. A computer-based method for determination of the cell-free layer width in microcirculation. Microcirculation (New York, N.Y. : 1994). 13: 199-207. PMID 16627362 DOI: 10.1080/10739680600556878  1
2006 Ji JW, Tsoukias NM, Goldman D, Popel AS. A computational model of oxygen transport in skeletal muscle for sprouting and splitting modes of angiogenesis. Journal of Theoretical Biology. 241: 94-108. PMID 16388825 DOI: 10.1016/J.Jtbi.2005.11.019  1
2006 Kim S, Popel AS, Intaglietta M, Johnson PC. Effect of erythrocyte aggregation at normal human levels on functional capillary density in rat spinotrapezius muscle. American Journal of Physiology. Heart and Circulatory Physiology. 290: H941-7. PMID 16183731 DOI: 10.1152/Ajpheart.00645.2005  1
2006 Kavdia M, Popel AS. Venular endothelium-derived NO can affect paired arteriole: a computational model. American Journal of Physiology. Heart and Circulatory Physiology. 290: H716-23. PMID 16155098 DOI: 10.1152/Ajpheart.00776.2005  1
2006 Karagiannis ED, Popel AS. Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model. Journal of Theoretical Biology. 238: 124-45. PMID 16005020 DOI: 10.1016/J.Jtbi.2005.05.020  1
2005 Popel AS, Johnson PC. Microcirculation and Hemorheology. Annual Review of Fluid Mechanics. 37: 43-69. PMID 21151769 DOI: 10.1146/Annurev.Fluid.37.042604.133933  1
2005 Bagchi P, Johnson PC, Popel AS. Computational fluid dynamic simulation of aggregation of deformable cells in a shear flow. Journal of Biomechanical Engineering. 127: 1070-80. PMID 16502649 DOI: 10.1115/1.2112907  1
2005 Liao Z, Popel AS, Brownell WE, Spector AA. Effect of voltage-dependent membrane properties on active force generation in cochlear outer hair cell. The Journal of the Acoustical Society of America. 118: 3737-46. PMID 16419818 DOI: 10.1121/1.2118387  1
2005 Mac Gabhann F, Yang MT, Popel AS. Monte Carlo simulations of VEGF binding to cell surface receptors in vitro. Biochimica Et Biophysica Acta. 1746: 95-107. PMID 16257459 DOI: 10.1016/J.Bbamcr.2005.09.004  1
2005 Liao Z, Popel AS, Brownell WE, Spector AA. High-frequency force generation in the constrained cochlear outer hair cell: a model study. Journal of the Association For Research in Otolaryngology : Jaro. 6: 378-89. PMID 16237583 DOI: 10.1007/S10162-005-0015-6  1
2005 Murdock DR, Ermilov SA, Spector AA, Popel AS, Brownell WE, Anvari B. Effects of chlorpromazine on mechanical properties of the outer hair cell plasma membrane. Biophysical Journal. 89: 4090-5. PMID 16199506 DOI: 10.1529/Biophysj.105.069872  1
2005 Spector AA, Popel AS, Eatock RA, Brownell WE. Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response. Annals of Biomedical Engineering. 33: 991-1002. PMID 16133908 DOI: 10.1007/S10439-005-5749-0  1
2005 Liao Z, Popel AS, Brownell WE, Spector AA. Modeling high-frequency electromotility of cochlear outer hair cell in microchamber experiment. The Journal of the Acoustical Society of America. 117: 2147-57. PMID 15898656 DOI: 10.1121/1.1863732  1
2005 Mac Gabhann F, Popel AS. Differential binding of VEGF isoforms to VEGF receptor 2 in the presence of neuropilin-1: a computational model. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2851-60. PMID 15708957 DOI: 10.1152/Ajpheart.01218.2004  1
2005 Kim S, Popel AS, Intaglietta M, Johnson PC. Aggregate formation of erythrocytes in postcapillary venules. American Journal of Physiology. Heart and Circulatory Physiology. 288: H584-90. PMID 15458951 DOI: 10.1152/Ajpheart.00690.2004  1
2005 Filion RJ, Popel AS. Intracoronary administration of FGF-2: a computational model of myocardial deposition and retention. American Journal of Physiology. Heart and Circulatory Physiology. 288: H263-79. PMID 15331374 DOI: 10.1152/Ajpheart.00205.2004  0.01
2005 Gabhann FM, Ji JW, Popel AS. Computational Model of VEGF Spatial Distribution in Muscle and Pro-Angiogenic Cell Therapy Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.0020127.Eor  1
2005 Popel AS, Kavdia M, Tsoukias NM. Effect of hemoglobin-based blood substitutes on nitric oxide transport : mathematical models The Keio Journal of Medicine. 52: 176-185. DOI: 10.1007/4-431-26651-8_12  1
2004 Karagiannis ED, Popel AS. A theoretical model of type I collagen proteolysis by matrix metalloproteinase (MMP) 2 and membrane type 1 MMP in the presence of tissue inhibitor of metalloproteinase 2. The Journal of Biological Chemistry. 279: 39105-14. PMID 15252025 DOI: 10.1074/Jbc.M403627200  1
2004 Filion RJ, Popel AS. A reaction-diffusion model of basic fibroblast growth factor interactions with cell surface receptors. Annals of Biomedical Engineering. 32: 645-63. PMID 15171620 DOI: 10.1023/B:Abme.0000030231.88326.78  0.01
2004 Kavdia M, Popel AS. Contribution of nNOS- and eNOS-derived NO to microvascular smooth muscle NO exposure. Journal of Applied Physiology (Bethesda, Md. : 1985). 97: 293-301. PMID 15033959 DOI: 10.1152/Japplphysiol.00049.2004  1
2004 Tsoukias NM, Kavdia M, Popel AS. A theoretical model of nitric oxide transport in arterioles: frequency- vs. amplitude-dependent control of cGMP formation. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1043-56. PMID 14592938 DOI: 10.1152/Ajpheart.00525.2003  1
2004 Bishop JJ, Nance PR, Popel AS, Intaglietta M, Johnson PC. Relationship between erythrocyte aggregate size and flow rate in skeletal muscle venules. American Journal of Physiology. Heart and Circulatory Physiology. 286: H113-20. PMID 12969894 DOI: 10.1152/Ajpheart.00587.2003  1
2004 Mac Gabhann F, Popel AS. Model of competitive binding of vascular endothelial growth factor and placental growth factor to VEGF receptors on endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 286: H153-64. PMID 12714333 DOI: 10.1152/Ajpheart.00254.2003  1
2003 Tsoukias NM, Popel AS. A model of nitric oxide capillary exchange. Microcirculation (New York, N.Y. : 1994). 10: 479-95. PMID 14745461 DOI: 10.1038/Sj.Mn.7800210  1
2003 Popel AS, Goldman D, Vadapalli A. Modeling of oxygen diffusion from the blood vessels to intracellular organelles. Advances in Experimental Medicine and Biology. 530: 485-95. PMID 14562744 DOI: 10.1007/978-1-4615-0075-9_46  1
2003 Kavdia M, Popel AS. Wall shear stress differentially affects NO level in arterioles for volume expanders and Hb-based O2 carriers. Microvascular Research. 66: 49-58. PMID 12826074 DOI: 10.1016/S0026-2862(03)00008-6  1
2003 Spector AA, Brownell WE, Popel AS. Effect of outer hair cell piezoelectricity on high-frequency receptor potentials. The Journal of the Acoustical Society of America. 113: 453-61. PMID 12558282 DOI: 10.1121/1.1526493  1
2002 Kavdia M, Pittman RN, Popel AS. Theoretical analysis of effects of blood substitute affinity and cooperativity on organ oxygen transport. Journal of Applied Physiology (Bethesda, Md. : 1985). 93: 2122-8. PMID 12391075 DOI: 10.1152/Japplphysiol.00676.2002  1
2002 Bishop JJ, Popel AS, Intaglietta M, Johnson PC. Effect of aggregation and shear rate on the dispersion of red blood cells flowing in venules. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1985-96. PMID 12384477 DOI: 10.1152/Ajpheart.00888.2001  1
2002 Sharan M, Popel AS. A compartmental model for oxygen transport in brain microcirculation in the presence of blood substitutes. Journal of Theoretical Biology. 216: 479-500. PMID 12151262 DOI: 10.1006/Jtbi.2002.3001  1
2002 Vadapalli A, Goldman D, Popel AS. Calculations of oxygen transport by red blood cells and hemoglobin solutions in capillaries. Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 30: 157-88. PMID 12066873 DOI: 10.1081/Bio-120004338  1
2002 Tsoukias NM, Popel AS. Erythrocyte consumption of nitric oxide in presence and absence of plasma-based hemoglobin. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2265-77. PMID 12003837 DOI: 10.1152/Ajpheart.01080.2001  1
2002 Kavdia M, Tsoukias NM, Popel AS. Model of nitric oxide diffusion in an arteriole: impact of hemoglobin-based blood substitutes. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2245-53. PMID 12003834 DOI: 10.1152/Ajpheart.00972.2001  1
2002 Spector AA, Ameen M, Charalambides PG, Popel AS. Nanostructure, effective properties, and deformation pattern of the cochlear outer hair cell cytoskeleton. Journal of Biomechanical Engineering. 124: 180-7. PMID 12002127 DOI: 10.1115/1.1448521  1
2002 Wootton DM, Popel AS, Alevriadou BR. An experimental and theoretical study on the dissolution of mural fibrin clots by tissue-type plasminogen activator. Biotechnology and Bioengineering. 77: 405-19. PMID 11787013 DOI: 10.1002/Bit.10127  1
2001 Bishop JJ, Nance PR, Popel AS, Intaglietta M, Johnson PC. Erythrocyte margination and sedimentation in skeletal muscle venules. American Journal of Physiology. Heart and Circulatory Physiology. 281: H951-8. PMID 11454602 DOI: 10.1152/Ajpheart.2001.281.2.H951  1
2001 Bishop JJ, Popel AS, Intaglietta M, Johnson PC. Effects of erythrocyte aggregation and venous network geometry on red blood cell axial migration. American Journal of Physiology. Heart and Circulatory Physiology. 281: H939-50. PMID 11454601 DOI: 10.1152/Ajpheart.2001.281.2.H939  1
2001 Brownell WE, Spector AA, Raphael RM, Popel AS. Micro- and nanomechanics of the cochlear outer hair cell. Annual Review of Biomedical Engineering. 3: 169-94. PMID 11447061 DOI: 10.1146/Annurev.Bioeng.3.1.169  1
2001 Spector AA, Ameen M, Popel AS. Simulation of motor-driven cochlear outer hair cell electromotility Biophysical Journal. 81: 11-24. PMID 11423391 DOI: 10.1016/S0006-3495(01)75676-7  1
2001 Bishop JJ, Nance PR, Popel AS, Intaglietta M, Johnson PC. Effect of erythrocyte aggregation on velocity profiles in venules. American Journal of Physiology. Heart and Circulatory Physiology. 280: H222-36. PMID 11123237 DOI: 10.1152/Ajpheart.2001.280.1.H222  1
2000 Eggleton CD, Vadapalli A, Roy TK, Popel AS. Calculations of intracapillary oxygen tension distributions in muscle Mathematical Biosciences. 167: 123-143. PMID 10998485 DOI: 10.1016/S0025-5564(00)00038-9  1
2000 Vadapalli A, Pittman RN, Popel AS. Estimating oxygen transport resistance of the microvascular wall. American Journal of Physiology. Heart and Circulatory Physiology. 279: H657-71. PMID 10924065 DOI: 10.1152/Ajpheart.2000.279.2.H657  1
2000 Bishop JJ, Nance PR, Popel AS, Intaglietta M, Johnson PC. Diameter changes in skeletal muscle venules during arterial pressure reduction. American Journal of Physiology. Heart and Circulatory Physiology. 279: H47-57. PMID 10899040 DOI: 10.1152/Ajpheart.2000.279.1.H47  1
2000 Ratnanather JT, Popel AS, Brownell WE. An analysis of the hydraulic conductivity of the extracisternal space of the cochlear outer hair cell. Journal of Mathematical Biology. 40: 372-82. PMID 10853798 DOI: 10.1007/S002850050185  1
2000 Raphael RM, Popel AS, Brownell WE. A membrane bending model of outer hair cell electromotility. Biophysical Journal. 78: 2844-62. PMID 10827967 DOI: 10.1016/S0006-3495(00)76827-5  1
1999 Golub AS, Popel AS, Zheng L, Pittman RN. Analysis of phosphorescence decay for nonuniform oxygen tension. Consequences of finite excitation flash duration. Advances in Experimental Medicine and Biology. 471: 649-59. PMID 10659199 DOI: 10.1007/978-1-4615-4717-4_75  1
1999 Gruben KG, Halperin HR, Popel AS, Tsitlik JE. Canine sternal force-displacement relationship during cardiopulmonary resuscitation Ieee Transactions On Biomedical Engineering. 46: 788-796. PMID 10396897 DOI: 10.1109/10.771188  1
1999 Spector AA, Brownell WE, Popel AS. Mechanical and electromotile characteristics of auditory outer hair cells. Medical & Biological Engineering & Computing. 37: 247-51. PMID 10396830 DOI: 10.1007/Bf02513294  1
1999 Popel AS, Pries AR, Slaaf DW. Microcirculation Physiome Project. Journal of Vascular Research. 36: 253-255. PMID 10393512 DOI: 10.1159/000025649  0.01
1999 Golub AS, Popel AS, Zheng L, Pittman RN. Analysis of phosphorescence decay in heterogeneous systems: consequences of finite excitation flash duration. Photochemistry and Photobiology. 69: 624-32. PMID 10378000 DOI: 10.1111/J.1751-1097.1999.Tb03338.X  1
1999 Spector AA, Brownell WE, Popel AS. Nonlinear active force generation by cochlear outer hair cell. The Journal of the Acoustical Society of America. 105: 2414-20. PMID 10212422 DOI: 10.1121/1.426846  1
1999 Pittman RN, Japee SA, Goldman D, Popel AS. Automated measurements of morphological, hemodynamic and oxygenation parameters in capillary networks and their use in computational models Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 1205.  1
1999 Wootton DM, Popel AS, Alevriadou BR. Model of lysis of mural platelet-fibrin thrombi Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 774.  1
1998 Eggleton CD, Roy TK, Popel AS. Predictions of capillary oxygen transport in the presence of fluorocarbon additives. American Journal of Physiology. Heart and Circulatory Physiology. 275: H2250-H2257. PMID 29586763 DOI: 10.1152/ajpheart.1998.275.6.H2250  1
1998 Spector AA, Brownell WE, Popel AS. Elastic properties of the composite outer hair cell wall. Annals of Biomedical Engineering. 26: 157-65. PMID 10355560 DOI: 10.1114/1.87  1
1998 Sharan M, Popel AS, Hudak ML, Koehler RC, Traystman RJ, Jones MD. An analysis of hypoxia in sheep brain using a mathematical model. Annals of Biomedical Engineering. 26: 48-59. PMID 10355550 DOI: 10.1114/1.50  1
1998 Das B, Johnson PC, Popel AS. Effect of nonaxisymmetric hematocrit distribution on non-Newtonian blood flow in small tubes. Biorheology. 35: 69-87. PMID 10211130 DOI: 10.1016/S0006-355X(98)00018-3  1
1998 Pittman RN, Golub AS, Popel AS, Zheng L. Interpretation of phosphorescence quenching measurements made in the presence of oxygen gradients. Advances in Experimental Medicine and Biology. 454: 375-83. PMID 9889914 DOI: 10.1007/978-1-4615-4863-8_45  1
1998 Popel AS, Greene AS, Ellis CG, Ley KF, Skalak TC, Tonellato PJ. The Microcirculation Physiome Project. Annals of Biomedical Engineering. 26: 911-3. PMID 9846930 DOI: 10.1114/1.112  0.01
1998 Eggleton CD, Roy TK, Popel AS. Predictions of capillary oxygen transport in the presence of fluorocarbon additives. The American Journal of Physiology. 275: H2250-7. PMID 9843826 DOI: 10.1152/Ajpheart.1998.275.6.H2250  1
1998 Sharan M, Gupta S, Popel AS. Parametric analysis of the relationship between end-capillary and mean tissue PO2 as predicted by a mathematical model. Journal of Theoretical Biology. 195: 439-49. PMID 9837701 DOI: 10.1006/Jtbi.1998.0805  1
1998 Popel AS, Pries AR, Slaaf DW, Miguel LSd, Alonso J, González-Fernández F, Osada Jdl, Montón M, Rodríguez-Feo JA, Guerra JI, Arriero MM, Rico L, Casado S, López-Farré A, Chajara A, et al. Joint Meeting of the Benelux Society for Microcirculation Journal of Vascular Research. 35: 194-233. PMID 9660628 DOI: 10.1159/000025584  0.01
1998 Spector AA, Brownell WE, Popel AS. Estimation of elastic moduli and bending stiffness of the anisotropic outer hair cell wall. The Journal of the Acoustical Society of America. 103: 1007-11. PMID 9479754 DOI: 10.1121/1.421217  1
1998 Spector AA, Brownell WE, Popel AS. Analysis of the micropipet experiment with the anisotropic outer hair cell wall. The Journal of the Acoustical Society of America. 103: 1001-6. PMID 9479753 DOI: 10.1121/1.421216  1
1998 Eggleton CD, Popel AS. Large deformation of red blood cell ghosts in a simple shear flow Physics of Fluids. 10: 1834-1845. DOI: 10.1063/1.869703  1
1997 Golub AS, Popel AS, Zheng L, Pittman RN. Analysis of phosphorescence in heterogeneous systems using distributions of quencher concentration. Biophysical Journal. 73: 452-65. PMID 9199808 DOI: 10.1016/S0006-3495(97)78084-6  1
1997 Sit PS, Spector AA, Lue AJ, Popel AS, Brownell WE. Micropipette aspiration on the outer hair cell lateral wall. Biophysical Journal. 72: 2812-9. PMID 9168055 DOI: 10.1016/S0006-3495(97)78923-9  1
1997 Cabel M, Meiselman HJ, Popel AS, Johnson PC. Contribution of red blood cell aggregation to venous vascular resistance in skeletal muscle. The American Journal of Physiology. 272: H1020-32. PMID 9124410 DOI: 10.1152/Ajpheart.1997.272.2.H1020  1
1996 Jerry RA, Popel AS, Brownell WE. Potential distribution for a spheroidal cell having a conductive membrane in an electric field. Ieee Transactions On Bio-Medical Engineering. 43: 970-2. PMID 9214813 DOI: 10.1109/10.532132  1
1996 Dutta A, Wang L, Meng H, Pittman RN, Popel AS. Oxygen tension profiles in isolated hamster retractor muscle at different temperatures. Microvascular Research. 51: 288-302. PMID 8992229 DOI: 10.1006/Mvre.1996.0028  1
1996 Spector AA, Brownell WE, Popel AS. A model for cochlear outer hair cell deformations in micropipette aspiration experiments: an analytical solution. Annals of Biomedical Engineering. 24: 241-9. PMID 8841728 DOI: 10.1007/Bf02648116  1
1996 Ratnanather JT, Zhi M, Brownell WE, Popel AS. Measurements and a model of the outer hair cell hydraulic conductivity. Hearing Research. 96: 33-40. PMID 8817304 DOI: 10.1016/0378-5955(96)00014-7  1
1996 Roy TK, Popel AS. Theoretical predictions of end-capillary PO2 in muscles of athletic and nonathletic animals at VO2max. The American Journal of Physiology. 271: H721-37. PMID 8770116 DOI: 10.1152/Ajpheart.1996.271.2.H721  1
1996 Spector AA, Brownell WE, Popel AS. A model for cochlear outer hair cell deformations in micropipette aspiration experiments: an analytical solution. Annals of Biomedical Engineering. 24: 241-9. PMID 8678356 DOI: 10.1007/BF02667353  1
1996 Ratnanather JT, Zhi M, Brownell WE, Popel AS. The ratio of elastic moduli of cochlear outer hair cells derived from osmotic experiments. The Journal of the Acoustical Society of America. 99: 1025-8. PMID 8609285 DOI: 10.1121/1.414631  1
1995 Dutta A, Popel AS. A Theoretical Analysis of Intracellular Oxygen Diffusion Journal of Theoretical Biology. 176: 433-445. PMID 8551742 DOI: 10.1006/Jtbi.1995.0211  1
1995 Jerry RA, Popel AS, Brownell WE. Outer hair cell length changes in an external electric field. II. The role of electrokinetic forces on the cell surface. The Journal of the Acoustical Society of America. 98: 2011-7. PMID 7593923 DOI: 10.1121/1.413319  1
1995 Jerry RA, Popel AS, Brownell WE. Outer hair cell length changes in an external electric field. I. The role of intracellular electro-osmotically generated pressure gradients. The Journal of the Acoustical Society of America. 98: 2000-10. PMID 7593922 DOI: 10.1121/1.413318  1
1994 Ellsworth ML, Ellis CG, Popel AS, Pittman RN. Role of Microvessels in Oxygen Supply to Tissue. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 9: 119-123. PMID 29209101 DOI: 10.1152/Physiologyonline.1994.9.3.119  1
1994 Ong J, Enden G, Popel AS. Converging three-dimensional Stokes flow of two fluids in a T-type bifurcation. Journal of Fluid Mechanics. 270: 51-72. PMID 28943654 DOI: 10.1017/S0022112094004192  0.01
1994 Torres Filho IP, Cyrino FZ, Popel AS, Bouskela E, Johnson PC. Morphometric analysis of the anastomosing arteriolar network in cat sartorius muscle. International Journal of Microcirculation, Clinical and Experimental / Sponsored by the European Society For Microcirculation. 14: 3-13. PMID 7960441 DOI: 10.1159/000178200  1
1994 Popel AS, Johnson PC, Kameneva MV, Wild MA. Capacity for red blood cell aggregation is higher in athletic mammalian species than in sedentary species. Journal of Applied Physiology (Bethesda, Md. : 1985). 77: 1790-4. PMID 7836201 DOI: 10.1152/Jappl.1994.77.4.1790  1
1994 Dutta A, Popel AS. Analysis of tissue diffusivity using mathematical models Advances in Experimental Medicine and Biology. 361: 17-29. PMID 7597940 DOI: 10.1007/978-1-4615-1875-4_3  1
1993 Wang CH, Popel AS. Effect of red blood cell shape on oxygen transport in capillaries. Mathematical Biosciences. 116: 89-110. PMID 8343620 DOI: 10.1016/0025-5564(93)90062-F  0.4
1993 Gruben KG, Guerci AD, Halperin HR, Popel AS, Tsitlik JE. Sternal force-displacement relationship during cardiopulmonary resuscitation Journal of Biomechanical Engineering. 115: 195-201. PMID 8326726 DOI: 10.1115/1.2894121  1
1992 Tsitlik JE, Halperin HR, Popel AS, Shoukas AA, Yin FC, Westerhof N. Modeling the circulation with three-terminal electrical networks containing special nonlinear capacitors. Annals of Biomedical Engineering. 20: 595-616. PMID 1449229 DOI: 10.1007/Bf02368608  1
1990 Bankman IN, Gruben KG, Halperin HR, Popel AS, Guerci AD, Tsitlik JE. Identification of Dynamic Mechanical Parameters of the Human Chest During Manual Cardiopulmonary Resuscitation Ieee Transactions On Biomedical Engineering. 37: 211-217. PMID 2312146 DOI: 10.1109/10.46262  1
1990 Weerappuli DP, Pittman RN, Popel AS. Effect of convection in capillaries on oxygen removal from arterioles in striated muscle. Journal of Theoretical Biology. 147: 275-88. PMID 2277509 DOI: 10.1016/S0022-5193(05)80057-8  1
1989 Popel AS, Pittman RN, Ellsworth ML. Rate of oxygen loss from arterioles is an order of magnitude higher than expected. The American Journal of Physiology. 256: H921-4. PMID 2923247 DOI: 10.1016/0883-9441(89)90050-6  1
1989 Sharan M, Jones MD, Koehler RC, Traystman RJ, Popel AS. A compartmental model for oxygen transport in brain microcirculation. Annals of Biomedical Engineering. 17: 13-38. PMID 2919811 DOI: 10.1007/Bf02364271  1
1989 Sherman TF, Popel AS, Koller A, Johnson PC. The cost of departure from optimal radii in microvascular networks. Journal of Theoretical Biology. 136: 245-65. PMID 2811392 DOI: 10.1016/S0022-5193(89)80162-6  1
1989 Hudak ML, Jones MD, Popel AS, Koehler RC, Traystman RJ, Zeger SL. Hemodilution causes size-dependent constriction of pial arterioles in the cat American Journal of Physiology - Heart and Circulatory Physiology. 257. PMID 2782448 DOI: 10.1152/Ajpheart.1989.257.3.H912  1
1989 Popel AS, Pittman RN, Ellsworth ML, Weerappuli DP. Measurements of oxygen flux from arterioles imply high permeability of perfused tissue to oxygen. Advances in Experimental Medicine and Biology. 248: 215-25. PMID 2782148 DOI: 10.1007/978-1-4684-5643-1_26  1
1989 Sharan M, Popel AS. Algorithm for computing oxygen dissociation curve with pH, PCO2, and CO in sheep blood. Journal of Biomedical Engineering. 11: 48-52. PMID 2494389 DOI: 10.1016/0141-5425(89)90165-9  1
1988 Ellsworth ML, Popel AS, Pittman RN. Assessment and impact of heterogeneities of convective oxygen transport parameters in capillaries of striated muscle: experimental and theoretical. Microvascular Research. 35: 341-62. PMID 3393095 DOI: 10.1016/0026-2862(88)90089-1  1
1988 Varela FE, Popel AS. Effect of intracapillary resistance to oxygen transport on the diffusional shunting between capillaries. Journal of Biomedical Engineering. 10: 400-5. PMID 3236866 DOI: 10.1016/0141-5425(88)90142-2  1
1987 Ellsworth ML, Liu A, Dawant B, Popel AS, Pittman RN. Analysis of vascular pattern and dimensions in arteriolar networks of the retractor muscle in young hamsters. Microvascular Research. 34: 168-83. PMID 3670113 DOI: 10.1016/0026-2862(87)90051-3  1
1983 Klitzman B, Popel AS, Duling BR. Oxygen transport in resting and contracting hamster cremaster muscles: Experimental and theoretical microvascular studies Microvascular Research. 25: 108-131. PMID 6835096 DOI: 10.1016/0026-2862(83)90047-X  1
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