Aleksander S. Popel - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering, Molecular Biology, General Biophysics

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhao C, Mirando AC, Sové RJ, Medeiros TX, Annex BH, Popel AS. A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology. Plos Computational Biology. 15: e1007468. PMID 31738746 DOI: 10.1371/journal.pcbi.1007468  0.6
2019 Zhang Y, Kontos CD, Annex BH, Popel AS. Angiopoietin-Tie Signaling Pathway in Endothelial Cells: A Computational Model. Iscience. 20: 497-511. PMID 31655061 DOI: 10.1016/j.isci.2019.10.006  0.48
2019 Jafarnejad M, Sové RJ, Danilova L, Mirando AC, Zhang Y, Yarchoan M, Tran PT, Pandey NB, Fertig EJ, Popel AS. Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma. Npj Systems Biology and Applications. 5: 29. PMID 31452933 DOI: 10.1038/s41540-019-0107-2  0.6
2019 Kim J, Lima E Silva R, Shmueli RB, Mirando AC, Tzeng SY, Pandey NB, Ben-Akiva E, Popel AS, Campochiaro PA, Green JJ. Anisotropic poly(lactic-co-glycolic acid) microparticles enable sustained release of a peptide for long-term inhibition of ocular neovascularization. Acta Biomaterialia. PMID 31374338 DOI: 10.1016/j.actbio.2019.07.054  0.6
2019 Mirando AC, Shen J, Lima E Silva R, Chu Z, Sass N, Lorenc VE, Green JJ, Campochiaro PA, Popel AS, Pandey NB. A collagen IV-derived peptide disrupts α5β1 integrin and potentiates Ang2-Tie2 signaling. Jci Insight. PMID 30668550 DOI: 10.1172/jci.insight.122043  0.6
2018 Zhang Y, Bazzazi H, Lima E Silva R, Pandey NB, Green JJ, Campochiaro PA, Popel AS. Three-Dimensional Transport Model for Intravitreal and Suprachoroidal Drug Injection. Investigative Ophthalmology & Visual Science. 59: 5266-5276. PMID 30383198 DOI: 10.1167/iovs.17-23632  0.6
2018 Bazzazi H, Zhang Y, Jafarnejad M, Popel AS. Computational modeling of synergistic interaction between αVβ3 integrin and VEGFR2 in endothelial cells: implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides. Journal of Theoretical Biology. PMID 30036530 DOI: 10.1016/j.jtbi.2018.06.029  0.6
2018 Bazzazi H, Zhang Y, Jafarnejad M, Isenberg JS, Annex BH, Popel AS. Computer Simulation of TSP1 Inhibition of VEGF-Akt-eNOS: An Angiogenesis Triple Threat. Frontiers in Physiology. 9: 644. PMID 29899706 DOI: 10.3389/fphys.2018.00644  0.6
2018 Jin K, Pandey NB, Popel AS. Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis. Breast Cancer Research : Bcr. 20: 54. PMID 29898755 DOI: 10.1186/s13058-018-0981-3  0.6
2018 Norton KA, Jin K, Popel AS. Modeling triple-negative breast cancer heterogeneity: effects of stromal macrophages, fibroblasts and tumor vasculature. Journal of Theoretical Biology. PMID 29750999 DOI: 10.1016/j.jtbi.2018.05.003  0.32
2018 Bressler EM, Kim J, Shmueli RB, Mirando AC, Bazzazi H, Lee E, Popel AS, Pandey NB, Green JJ. Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells. Journal of Biomedical Materials Research. Part A. PMID 29424479 DOI: 10.1002/jbm.a.36360  0.6
2017 Barbhuiya MA, Mirando AC, Simons BW, Lemtiri-Chlieh G, Green JJ, Popel AS, Pandey NB, Tran PT. Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma. Oncotarget. 8: 101520-101534. PMID 29254183 DOI: 10.18632/oncotarget.21148  0.6
2017 Jin K, Pandey NB, Popel AS. Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis. Oncotarget. 8: 60210-60222. PMID 28947965 DOI: 10.18632/oncotarget.19417  0.6
2017 Jin K, Pandey NB, Popel AS. Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis. Oncotarget. PMID 28753581 DOI: 10.18632/oncotarget.19417  0.6
2017 Norton KA, Wallace T, Pandey NB, Popel AS. An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia. Bmc Systems Biology. 11: 68. PMID 28693495 DOI: 10.1186/s12918-017-0445-x  0.6
2017 Bazzazi H, Isenberg JS, Popel AS. Corrigendum: Inhibition of VEGFR2 Activation and Its Downstream Signaling to ERK1/2 and Calcium by Thrombospondin-1 (TSP1): In silico Investigation. Frontiers in Physiology. 8: 147. PMID 28275355 DOI: 10.3389/fphys.2017.00147  0.6
2017 Bazzazi H, Isenberg JS, Popel AS. Inhibition of VEGFR2 Activation and Its Downstream Signaling to ERK1/2 and Calcium by Thrombospondin-1 (TSP1): In silico Investigation. Frontiers in Physiology. 8: 48. PMID 28220078 DOI: 10.3389/fphys.2017.00048  0.6
2017 Bazzazi H, Popel AS. Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells. Plos Computational Biology. 13: e1005332. PMID 28178265 DOI: 10.1371/journal.pcbi.1005332  0.6
2017 Lima E Silva R, Kanan Y, Mirando AC, Kim J, Shmueli RB, Lorenc VE, Fortmann SD, Sciamanna J, Pandey NB, Green JJ, Popel AS, Campochiaro PA. Tyrosine kinase blocking collagen IV-derived peptide suppresses ocular neovascularization and vascular leakage. Science Translational Medicine. 9. PMID 28100839 DOI: 10.1126/scitranslmed.aai8030  0.6
2016 Dore-Savard L, Lee E, Kakkad S, Popel AS, Bhujwalla ZM. The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts. Scientific Reports. 6: 39460. PMID 27995973 DOI: 10.1038/srep39460  0.6
2016 Kim J, Mirando AC, Popel AS, Green JJ. Gene delivery nanoparticles to modulate angiogenesis. Advanced Drug Delivery Reviews. PMID 27913120 DOI: 10.1016/j.addr.2016.11.003  0.6
2016 Chu LH, Ganta VC, Choi MH, Chen G, Finley SD, Annex BH, Popel AS. A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF165b in peripheral arterial disease in human and mouse. Scientific Reports. 6: 37030. PMID 27853189 DOI: 10.1038/srep37030  0.48
2016 Noren DP, Chou WH, Lee SH, Qutub AA, Warmflash A, Wagner DS, Popel AS, Levchenko A. Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses. Science Signaling. 9: ra20. PMID 26905425 DOI: 10.1126/scisignal.aad3188  0.56
2015 Chu LH, Annex BH, Popel AS. Computational drug repositioning for peripheral arterial disease: prediction of anti-inflammatory and pro-angiogenic therapeutics. Frontiers in Pharmacology. 6: 179. PMID 26379552 DOI: 10.3389/fphar.2015.00179  0.48
2015 Fertig EJ, Lee E, Pandey NB, Popel AS. Analysis of gene expression of secreted factors associated with breast cancer metastases in breast cancer subtypes. Scientific Reports. 5: 12133. PMID 26173622 DOI: 10.1038/srep12133  0.56
2015 Norton KA, Popel AS, Pandey NB. Heterogeneity of chemokine cell-surface receptor expression in triple-negative breast cancer. American Journal of Cancer Research. 5: 1295-307. PMID 26101698  0.6
2015 Chu LH, Vijay CG, Annex BH, Bader JS, Popel AS. PADPIN: protein-protein interaction networks of angiogenesis, arteriogenesis, and inflammation in peripheral arterial disease. Physiological Genomics. 47: 331-43. PMID 26058837 DOI: 10.1152/physiolgenomics.00125.2014  0.56
2015 Lee E, Pandey NB, Popel AS. Crosstalk between cancer cells and blood endothelial and lymphatic endothelial cells in tumour and organ microenvironment. Expert Reviews in Molecular Medicine. 17: e3. PMID 25634527 DOI: 10.1017/erm.2015.2  0.56
2015 Kim E, Lee E, Plummer C, Gil S, Popel AS, Pathak AP. Vasculature-specific MRI reveals differential anti-angiogenic effects of a biomimetic peptide in an orthotopic breast cancer model. Angiogenesis. 18: 125-36. PMID 25408417 DOI: 10.1007/s10456-014-9450-5  0.56
2015 Finley SD, Chu LH, Popel AS. Computational systems biology approaches to anti-angiogenic cancer therapeutics. Drug Discovery Today. 20: 187-97. PMID 25286370 DOI: 10.1016/j.drudis.2014.09.026  0.56
2014 Lee E, Lee SJ, Koskimaki JE, Han Z, Pandey NB, Popel AS. Inhibition of breast cancer growth and metastasis by a biomimetic peptide. Scientific Reports. 4: 7139. PMID 25409905 DOI: 10.1038/srep07139  0.56
2014 Rosca EV, Penet MF, Mori N, Koskimaki JE, Lee E, Pandey NB, Bhujwalla ZM, Popel AS. A biomimetic collagen derived peptide exhibits anti-angiogenic activity in triple negative breast cancer. Plos One. 9: e111901. PMID 25384034 DOI: 10.1371/journal.pone.0111901  0.56
2014 Chu LH, Lee E, Bader JS, Popel AS. Angiogenesis interactome and time course microarray data reveal the distinct activation patterns in endothelial cells. Plos One. 9: e110871. PMID 25329517 DOI: 10.1371/journal.pone.0110871  0.56
2014 Norton KA, Han Z, Popel AS, Pandey NB. Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells. Oncotargets and Therapy. 7: 1571-82. PMID 25228815 DOI: 10.2147/OTT.S65055  0.56
2014 Norton KA, Popel AS. An agent-based model of cancer stem cell initiated avascular tumour growth and metastasis: the effect of seeding frequency and location. Journal of the Royal Society, Interface / the Royal Society. 11: 20140640. PMID 25185580 DOI: 10.1098/rsif.2014.0640  0.56
2014 Lee E, Fertig EJ, Jin K, Sukumar S, Pandey NB, Popel AS. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nature Communications. 5: 4715. PMID 25178650 DOI: 10.1038/ncomms5715  0.56
2014 Lee E, Pandey NB, Popel AS. Lymphatic endothelial cells support tumor growth in breast cancer. Scientific Reports. 4: 5853. PMID 25068296 DOI: 10.1038/srep05853  0.56
2014 Vempati P, Popel AS, Mac Gabhann F. Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning. Cytokine & Growth Factor Reviews. 25: 1-19. PMID 24332926 DOI: 10.1016/j.cytogfr.2013.11.002  1
2014 Logsdon EA, Finley SD, Popel AS, Mac Gabhann F. A systems biology view of blood vessel growth and remodelling. Journal of Cellular and Molecular Medicine. 18: 1491-508. PMID 24237862 DOI: 10.1111/jcmm.12164  0.56
2014 Lee E, Pandey NB, Popel AS. Pre-treatment of mice with tumor-conditioned media accelerates metastasis to lymph nodes and lungs: a new spontaneous breast cancer metastasis model. Clinical & Experimental Metastasis. 31: 67-79. PMID 23963763 DOI: 10.1007/s10585-013-9610-9  0.56
2013 Tan WH, Popel AS, Mac Gabhann F. Computational model of VEGFR2 pathway to ERK activation and modulation through receptor trafficking. Cellular Signalling. 25: 2496-510. PMID 23993967 DOI: 10.1016/j.cellsig.2013.08.015  1
2013 Finley SD, Dhar M, Popel AS. Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice. Frontiers in Oncology. 3: 196. PMID 23908970 DOI: 10.3389/fonc.2013.00196  0.56
2013 Shmueli RB, Ohnaka M, Miki A, Pandey NB, Lima e Silva R, Koskimaki JE, Kim J, Popel AS, Campochiaro PA, Green JJ. Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide. Biomaterials. 34: 7544-51. PMID 23849876 DOI: 10.1016/j.biomaterials.2013.06.044  0.56
2013 Tan WH, Popel AS, Mac Gabhann F. Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation. Plos One. 8: e67438. PMID 23805312 DOI: 10.1371/journal.pone.0067438  1
2013 Finley SD, Popel AS. Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions. Journal of the National Cancer Institute. 105: 802-11. PMID 23670728 DOI: 10.1093/jnci/djt093  0.56
2013 Lee E, Koskimaki JE, Pandey NB, Popel AS. Inhibition of lymphangiogenesis and angiogenesis in breast tumor xenografts and lymph nodes by a peptide derived from transmembrane protein 45A. Neoplasia (New York, N.Y.). 15: 112-24. PMID 23441126 DOI: 10.1593/neo.121638  0.56
2013 Imoukhuede PI, Dokun AO, Annex BH, Popel AS. Endothelial cell-by-cell profiling reveals the temporal dynamics of VEGFR1 and VEGFR2 membrane localization after murine hindlimb ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1085-93. PMID 23376830 DOI: 10.1152/ajpheart.00514.2012  0.48
2013 Koskimaki JE, Lee E, Chen W, Rivera CG, Rosca EV, Pandey NB, Popel AS. Synergy between a collagen IV mimetic peptide and a somatotropin-domain derived peptide as angiogenesis and lymphangiogenesis inhibitors. Angiogenesis. 16: 159-70. PMID 23053781 DOI: 10.1007/s10456-012-9308-7  0.56
2012 Liu G, Mac Gabhann F, Popel AS. Effects of fiber type and size on the heterogeneity of oxygen distribution in exercising skeletal muscle. Plos One. 7: e44375. PMID 23028531 DOI: 10.1371/journal.pone.0044375  1
2012 Chu LH, Rivera CG, Popel AS, Bader JS. Constructing the angiome: a global angiogenesis protein interaction network. Physiological Genomics. 44: 915-24. PMID 22911453 DOI: 10.1152/physiolgenomics.00181.2011  0.56
2012 Kim E, Stamatelos S, Cebulla J, Bhujwalla ZM, Popel AS, Pathak AP. Multiscale imaging and computational modeling of blood flow in the tumor vasculature. Annals of Biomedical Engineering. 40: 2425-41. PMID 22565817 DOI: 10.1007/s10439-012-0585-5  0.36
2012 Finley SD, Popel AS. Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms. The Aaps Journal. 14: 500-9. PMID 22547351 DOI: 10.1208/s12248-012-9363-4  0.56
2012 Koskimaki JE, Rosca EV, Rivera CG, Lee E, Chen W, Pandey NB, Popel AS. Serpin-derived peptides are antiangiogenic and suppress breast tumor xenograft growth. Translational Oncology. 5: 92-7. PMID 22496925 DOI: 10.1593/tlo.11244  0.56
2012 Rosca EV, Lal B, Koskimaki JE, Popel AS, Laterra J. Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth. Anti-Cancer Drugs. 23: 706-12. PMID 22495619 DOI: 10.1097/CAD.0b013e3283531041  0.56
2012 Li X, Popel AS, Karniadakis GE. Blood-plasma separation in Y-shaped bifurcating microfluidic channels: a dissipative particle dynamics simulation study. Physical Biology. 9: 026010. PMID 22476709 DOI: 10.1088/1478-3975/9/2/026010  0.56
2012 Rosca EV, Koskimaki JE, Pandey NB, Tamiz AP, Popel AS. Structure-activity relationship study of collagen-derived anti-angiogenic biomimetic peptides. Chemical Biology & Drug Design. 80: 27-37. PMID 22405100 DOI: 10.1111/j.1747-0285.2012.01376.x  0.56
2012 Stefanini MO, Qutub AA, Mac Gabhann F, Popel AS. Computational models of VEGF-associated angiogenic processes in cancer. Mathematical Medicine and Biology : a Journal of the Ima. 29: 85-94. PMID 21266494 DOI: 10.1093/imammb/dqq025  1
2011 Finley SD, Engel-Stefanini MO, Imoukhuede PI, Popel AS. Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies. Bmc Systems Biology. 5: 193. PMID 22104283 DOI: 10.1186/1752-0509-5-193  0.56
2011 Yen P, Finley SD, Engel-Stefanini MO, Popel AS. A two-compartment model of VEGF distribution in the mouse. Plos One. 6: e27514. PMID 22087332 DOI: 10.1371/journal.pone.0027514  0.56
2011 Rivera CG, Mellberg S, Claesson-Welsh L, Bader JS, Popel AS. Analysis of VEGF--a regulated gene expression in endothelial cells to identify genes linked to angiogenesis. Plos One. 6: e24887. PMID 21931866 DOI: 10.1371/journal.pone.0024887  0.56
2011 Lee E, Rosca EV, Pandey NB, Popel AS. Small peptides derived from somatotropin domain-containing proteins inhibit blood and lymphatic endothelial cell proliferation, migration, adhesion and tube formation. The International Journal of Biochemistry & Cell Biology. 43: 1812-21. PMID 21920451 DOI: 10.1016/j.biocel.2011.08.020  0.56
2011 Rosca EV, Koskimaki JE, Pandey NB, Wolff AC, Popel AS. Development of a biomimetic peptide derived from collagen IV with anti-angiogenic activity in breast cancer. Cancer Biology & Therapy. 12: 808-17. PMID 21878750 DOI: 10.4161/cbt.12.9.17677  0.56
2011 Rivera CG, Rosca EV, Pandey NB, Koskimaki JE, Bader JS, Popel AS. Novel peptide-specific quantitative structure-activity relationship (QSAR) analysis applied to collagen IV peptides with antiangiogenic activity. Journal of Medicinal Chemistry. 54: 6492-500. PMID 21866962 DOI: 10.1021/jm200114f  0.56
2011 Rivera CG, Bader JS, Popel AS. Angiogenesis-associated crosstalk between collagens, CXC chemokines, and thrombospondin domain-containing proteins. Annals of Biomedical Engineering. 39: 2213-22. PMID 21590489 DOI: 10.1007/s10439-011-0325-2  0.56
2011 Vempati P, Popel AS, Mac Gabhann F. Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis. Bmc Systems Biology. 5: 59. PMID 21535871 DOI: 10.1186/1752-0509-5-59  1
2011 Rosca EV, Koskimaki JE, Rivera CG, Pandey NB, Tamiz AP, Popel AS. Anti-angiogenic peptides for cancer therapeutics. Current Pharmaceutical Biotechnology. 12: 1101-16. PMID 21470139 DOI: 10.2174/138920111796117300  0.56
2011 Liu G, Qutub AA, Vempati P, Mac Gabhann F, Popel AS. Module-based multiscale simulation of angiogenesis in skeletal muscle. Theoretical Biology & Medical Modelling. 8: 6. PMID 21463529 DOI: 10.1186/1742-4682-8-6  1
2011 Waters SL, Alastruey J, Beard DA, Bovendeerd PH, Davies PF, Jayaraman G, Jensen OE, Lee J, Parker KH, Popel AS, Secomb TW, Siebes M, Sherwin SJ, Shipley RJ, Smith NP, et al. Theoretical models for coronary vascular biomechanics: progress & challenges. Progress in Biophysics and Molecular Biology. 104: 49-76. PMID 21040741 DOI: 10.1016/j.pbiomolbio.2010.10.001  0.56
2010 Stefanini MO, Wu FT, Mac Gabhann F, Popel AS. Increase of plasma VEGF after intravenous administration of bevacizumab is predicted by a pharmacokinetic model. Cancer Research. 70: 9886-94. PMID 21118974 DOI: 10.1158/0008-5472.CAN-10-1419  1
2010 Fedosov DA, Caswell B, Popel AS, Karniadakis GE. Blood flow and cell-free layer in microvessels. Microcirculation (New York, N.Y. : 1994). 17: 615-28. PMID 21044216 DOI: 10.1111/j.1549-8719.2010.00056.x  0.56
2010 Mac Gabhann F, Qutub AA, Annex BH, Popel AS. Systems biology of pro-angiogenic therapies targeting the VEGF system. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 694-707. PMID 20890966 DOI: 10.1002/wsbm.92  1
2010 Mac Gabhann F, Annex BH, Popel AS. Gene therapy from the perspective of systems biology. Current Opinion in Molecular Therapeutics. 12: 570-7. PMID 20886389  1
2010 Vempati P, Mac Gabhann F, Popel AS. Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model. Plos One. 5: e11860. PMID 20686621 DOI: 10.1371/journal.pone.0011860  1
2010 Wu FT, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS. VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model. American Journal of Physiology. Heart and Circulatory Physiology. 298: H2174-91. PMID 20382861 DOI: 10.1152/ajpheart.00365.2009  1
2010 Koskimaki JE, Karagiannis ED, Tang BC, Hammers H, Watkins DN, Pili R, Popel AS. Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model. Bmc Cancer. 10: 29. PMID 20122172 DOI: 10.1186/1471-2407-10-29  0.56
2010 Wu FT, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS. A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use. Journal of Cellular and Molecular Medicine. 14: 528-52. PMID 19840194 DOI: 10.1111/j.1582-4934.2009.00941.x  1
2009 Popel AS, Hunter PJ. Systems biology and physiome projects. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 1: 153-8. PMID 20835988 DOI: 10.1002/wsbm.67  0.56
2009 Stefanini MO, Wu FT, Mac Gabhann F, Popel AS. The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling. Plos Computational Biology. 5: e1000622. PMID 20041209 DOI: 10.1371/journal.pcbi.1000622  1
2009 Koskimaki JE, Karagiannis ED, Rosca EV, Vesuna F, Winnard PT, Raman V, Bhujwalla ZM, Popel AS. Peptides derived from type IV collagen, CXC chemokines, and thrombospondin-1 domain-containing proteins inhibit neovascularization and suppress tumor growth in MDA-MB-231 breast cancer xenografts. Neoplasia (New York, N.Y.). 11: 1285-91. PMID 20019836 DOI: 10.1593/neo.09620  0.56
2009 Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA. Computational analysis of the tether-pulling experiment to probe plasma membrane-cytoskeleton interaction in cells. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 80: 041905. PMID 19905340 DOI: 10.1103/PhysRevE.80.041905  0.56
2009 Wu FT, Stefanini MO, Mac Gabhann F, Popel AS. Modeling of growth factor-receptor systems from molecular-level protein interaction networks to whole-body compartment models. Methods in Enzymology. 467: 461-97. PMID 19897104 DOI: 10.1016/S0076-6879(09)67018-X  1
2009 Wu FT, Stefanini MO, Mac Gabhann F, Popel AS. A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap. Plos One. 4: e5108. PMID 19352513 DOI: 10.1371/journal.pone.0005108  1
2009 Wu FT, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS. Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport. Physiological Genomics. 38: 29-41. PMID 19351908 DOI: 10.1152/physiolgenomics.00031.2009  1
2009 Qutub AA, Mac Gabhann F, Karagiannis ED, Vempati P, Popel AS. Multiscale models of angiogenesis. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 28: 14-31. PMID 19349248 DOI: 10.1109/MEMB.2009.931791  1
2009 Chen K, Pittman RN, Popel AS. Hemorrhagic shock and nitric oxide release from erythrocytic nitric oxide synthase: a quantitative analysis. Microvascular Research. 78: 107-18. PMID 19285090 DOI: 10.1016/j.mvr.2009.02.009  0.56
2009 Cano Mdel V, Karagiannis ED, Soliman M, Bakir B, Zhuang W, Popel AS, Gehlbach PL. A peptide derived from type 1 thrombospondin repeat-containing protein WISP-1 inhibits corneal and choroidal neovascularization. Investigative Ophthalmology & Visual Science. 50: 3840-5. PMID 19279315 DOI: 10.1167/iovs.08-2607  1
2009 Qutub AA, Liu G, Vempati P, Popel AS. Integration of angiogenesis modules at multiple scales: from molecular to tissue. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 316-27. PMID 19209711  0.8
2009 Qutub AA, Popel AS. Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting. Bmc Systems Biology. 3: 13. PMID 19171061 DOI: 10.1186/1752-0509-3-13  0.76
2008 Karagiannis ED, Popel AS. A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 13775-80. PMID 18780781 DOI: 10.1073/pnas.0803241105  1
2008 Stefanini MO, Wu FT, Mac Gabhann F, Popel AS. A compartment model of VEGF distribution in blood, healthy and diseased tissues. Bmc Systems Biology. 2: 77. PMID 18713470 DOI: 10.1186/1752-0509-2-77  1
2008 Mac Gabhann F, Popel AS. Systems biology of vascular endothelial growth factors. Microcirculation (New York, N.Y. : 1994). 15: 715-38. PMID 18608994 DOI: 10.1080/10739680802095964  1
2008 Qutub AA, Popel AS. Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. Molecular and Cellular Biology. 28: 5106-19. PMID 18559422 DOI: 10.1128/MCB.00060-08  0.76
2008 Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA. Modeling the mechanics of tethers pulled from the cochlear outer hair cell membrane. Journal of Biomechanical Engineering. 130: 031007. PMID 18532856 DOI: 10.1115/1.2907758  0.56
2008 Sharan M, Vovenko EP, Vadapalli A, Popel AS, Pittman RN. Experimental and theoretical studies of oxygen gradients in rat pial microvessels. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1597-604. PMID 18506196 DOI: 10.1038/jcbfm.2008.51  0.56
2008 Demetriades AM, Deering T, Liu H, Lu L, Gehlbach P, Packer JD, Mac Gabhann F, Popel AS, Wei LL, Campochiaro PA. Trans-scleral delivery of antiangiogenic proteins. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 24: 70-9. PMID 18370877 DOI: 10.1089/jop.2007.0061  1
2008 Chen K, Pittman RN, Popel AS. Nitric oxide in the vasculature: where does it come from and where does it go? A quantitative perspective. Antioxidants & Redox Signaling. 10: 1185-98. PMID 18331202 DOI: 10.1089/ars.2007.1959  0.56
2008 Karagiannis ED, Popel AS. Novel anti-angiogenic peptides derived from ELR-containing CXC chemokines. Journal of Cellular Biochemistry. 104: 1356-63. PMID 18307172 DOI: 10.1002/jcb.21712  1
2008 Chen K, Piknova B, Pittman RN, Schechter AN, Popel AS. Nitric oxide from nitrite reduction by hemoglobin in the plasma and erythrocytes. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 18: 47-60. PMID 17964300 DOI: 10.1016/j.niox.2007.09.088  0.56
2007 Kut C, Mac Gabhann F, Popel AS. Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer. British Journal of Cancer. 97: 978-85. PMID 17912242 DOI: 10.1038/sj.bjc.6603923  1
2007 Liao Z, Feng S, Popel AS, Brownell WE, Spector AA. Outer hair cell active force generation in the cochlear environment. The Journal of the Acoustical Society of America. 122: 2215-25. PMID 17902857 DOI: 10.1121/1.2776154  0.56
2007 Ji JW, Mac Gabhann F, Popel AS. Skeletal muscle VEGF gradients in peripheral arterial disease: simulations of rest and exercise. American Journal of Physiology. Heart and Circulatory Physiology. 293: H3740-9. PMID 17890434 DOI: 10.1152/ajpheart.00009.2007  1
2007 Vempati P, Karagiannis ED, Popel AS. A biochemical model of matrix metalloproteinase 9 activation and inhibition. The Journal of Biological Chemistry. 282: 37585-96. PMID 17848556 DOI: 10.1074/jbc.M611500200  1
2007 Hazarika S, Dokun AO, Li Y, Popel AS, Kontos CD, Annex BH. Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1. Circulation Research. 101: 948-56. PMID 17823371 DOI: 10.1161/CIRCRESAHA.107.160630  0.56
2007 Qutub AA, Popel AS. Three autocrine feedback loops determine HIF1 alpha expression in chronic hypoxia. Biochimica Et Biophysica Acta. 1773: 1511-25. PMID 17720260 DOI: 10.1016/j.bbamcr.2007.07.004  0.76
2007 Karagiannis ED, Popel AS. Peptides derived from type I thrombospondin repeat-containing proteins of the CCN family inhibit proliferation and migration of endothelial cells. The International Journal of Biochemistry & Cell Biology. 39: 2314-23. PMID 17707681 DOI: 10.1016/j.biocel.2007.06.018  1
2007 Tsoukias NM, Goldman D, Vadapalli A, Pittman RN, Popel AS. A computational model of oxygen delivery by hemoglobin-based oxygen carriers in three-dimensional microvascular networks. Journal of Theoretical Biology. 248: 657-74. PMID 17686494 DOI: 10.1016/j.jtbi.2007.06.012  0.56
2007 Chen K, Pittman RN, Popel AS. Vascular smooth muscle NO exposure from intraerythrocytic SNOHb: a mathematical model. Antioxidants & Redox Signaling. 9: 1097-110. PMID 17536957 DOI: 10.1089/ars.2007.1594  0.56
2007 Karagiannis ED, Popel AS. Anti-angiogenic peptides identified in thrombospondin type I domains. Biochemical and Biophysical Research Communications. 359: 63-9. PMID 17531201 DOI: 10.1016/j.bbrc.2007.05.041  1
2007 Mac Gabhann F, Popel AS. Dimerization of VEGF receptors and implications for signal transduction: a computational study. Biophysical Chemistry. 128: 125-39. PMID 17442480 DOI: 10.1016/j.bpc.2007.03.010  1
2007 Mac Gabhann F, Ji JW, Popel AS. Multi-scale computational models of pro-angiogenic treatments in peripheral arterial disease. Annals of Biomedical Engineering. 35: 982-94. PMID 17436110 DOI: 10.1007/s10439-007-9303-0  1
2007 Zhi M, Ratnanather JT, Ceyhan E, Popel AS, Brownell WE. Hypotonic swelling of salicylate-treated cochlear outer hair cells. Hearing Research. 228: 95-104. PMID 17400411 DOI: 10.1016/j.heares.2007.02.007  0.56
2007 Mac Gabhann F, Demetriades AM, Deering T, Packer JD, Shah SM, Duh E, Campochiaro PA, Popel AS. Protein transport to choroid and retina following periocular injection: theoretical and experimental study. Annals of Biomedical Engineering. 35: 615-30. PMID 17277991 DOI: 10.1007/s10439-006-9238-x  1
2007 Karagiannis ED, Popel AS. Identification of novel short peptides derived from the alpha 4, alpha 5, and alpha 6 fibrils of type IV collagen with anti-angiogenic properties. Biochemical and Biophysical Research Communications. 354: 434-9. PMID 17239819 DOI: 10.1016/j.bbrc.2006.12.231  1
2007 Mac Gabhann F, Ji JW, Popel AS. VEGF gradients, receptor activation, and sprout guidance in resting and exercising skeletal muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 102: 722-34. PMID 17038488 DOI: 10.1152/japplphysiol.00800.2006  1
2007 Mac Gabhann F, Popel AS. Interactions of VEGF isoforms with VEGFR-1, VEGFR-2, and neuropilin in vivo: a computational model of human skeletal muscle. American Journal of Physiology. Heart and Circulatory Physiology. 292: H459-74. PMID 16980341 DOI: 10.1152/ajpheart.00637.2006  1
2006 Mac Gabhann F, Popel AS. Targeting neuropilin-1 to inhibit VEGF signaling in cancer: Comparison of therapeutic approaches. Plos Computational Biology. 2: e180. PMID 17196035 DOI: 10.1371/journal.pcbi.0020180  1
2006 Mac Gabhann F, Ji JW, Popel AS. Computational model of vascular endothelial growth factor spatial distribution in muscle and pro-angiogenic cell therapy. Plos Computational Biology. 2: e127. PMID 17002494 DOI: 10.1371/journal.pcbi.0020127  1
2006 Qutub AA, Popel AS. A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha. Journal of Cell Science. 119: 3467-80. PMID 16899821 DOI: 10.1242/jcs.03087  0.76
2006 Ji JW, Tsoukias NM, Goldman D, Popel AS. A computational model of oxygen transport in skeletal muscle for sprouting and splitting modes of angiogenesis. Journal of Theoretical Biology. 241: 94-108. PMID 16388825 DOI: 10.1016/j.jtbi.2005.11.019  0.56
2006 Kavdia M, Popel AS. Venular endothelium-derived NO can affect paired arteriole: a computational model. American Journal of Physiology. Heart and Circulatory Physiology. 290: H716-23. PMID 16155098 DOI: 10.1152/ajpheart.00776.2005  0.56
2006 Karagiannis ED, Popel AS. Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model. Journal of Theoretical Biology. 238: 124-45. PMID 16005020 DOI: 10.1016/j.jtbi.2005.05.020  1
2005 Bagchi P, Johnson PC, Popel AS. Computational fluid dynamic simulation of aggregation of deformable cells in a shear flow. Journal of Biomechanical Engineering. 127: 1070-80. PMID 16502649 DOI: 10.1115/1.2112907  0.56
2005 Liao Z, Popel AS, Brownell WE, Spector AA. Effect of voltage-dependent membrane properties on active force generation in cochlear outer hair cell. The Journal of the Acoustical Society of America. 118: 3737-46. PMID 16419818 DOI: 10.1121/1.2118387  0.56
2005 Mac Gabhann F, Yang MT, Popel AS. Monte Carlo simulations of VEGF binding to cell surface receptors in vitro. Biochimica Et Biophysica Acta. 1746: 95-107. PMID 16257459 DOI: 10.1016/j.bbamcr.2005.09.004  0.56
2005 Liao Z, Popel AS, Brownell WE, Spector AA. High-frequency force generation in the constrained cochlear outer hair cell: a model study. Journal of the Association For Research in Otolaryngology : Jaro. 6: 378-89. PMID 16237583 DOI: 10.1007/s10162-005-0015-6  0.56
2005 Murdock DR, Ermilov SA, Spector AA, Popel AS, Brownell WE, Anvari B. Effects of chlorpromazine on mechanical properties of the outer hair cell plasma membrane. Biophysical Journal. 89: 4090-5. PMID 16199506 DOI: 10.1529/biophysj.105.069872  0.56
2005 Spector AA, Popel AS, Eatock RA, Brownell WE. Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response. Annals of Biomedical Engineering. 33: 991-1002. PMID 16133908 DOI: 10.1007/s10439-005-5749-0  0.56
2005 Liao Z, Popel AS, Brownell WE, Spector AA. Modeling high-frequency electromotility of cochlear outer hair cell in microchamber experiment. The Journal of the Acoustical Society of America. 117: 2147-57. PMID 15898656 DOI: 10.1121/1.1863732  0.56
2005 Mac Gabhann F, Popel AS. Differential binding of VEGF isoforms to VEGF receptor 2 in the presence of neuropilin-1: a computational model. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2851-60. PMID 15708957 DOI: 10.1152/ajpheart.01218.2004  1
2004 Karagiannis ED, Popel AS. A theoretical model of type I collagen proteolysis by matrix metalloproteinase (MMP) 2 and membrane type 1 MMP in the presence of tissue inhibitor of metalloproteinase 2. The Journal of Biological Chemistry. 279: 39105-14. PMID 15252025 DOI: 10.1074/jbc.M403627200  1
2004 Kavdia M, Popel AS. Contribution of nNOS- and eNOS-derived NO to microvascular smooth muscle NO exposure. Journal of Applied Physiology (Bethesda, Md. : 1985). 97: 293-301. PMID 15033959 DOI: 10.1152/japplphysiol.00049.2004  0.56
2004 Tsoukias NM, Kavdia M, Popel AS. A theoretical model of nitric oxide transport in arterioles: frequency- vs. amplitude-dependent control of cGMP formation. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1043-56. PMID 14592938 DOI: 10.1152/ajpheart.00525.2003  0.56
2004 Mac Gabhann F, Popel AS. Model of competitive binding of vascular endothelial growth factor and placental growth factor to VEGF receptors on endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 286: H153-64. PMID 12714333 DOI: 10.1152/ajpheart.00254.2003  1
2003 Tsoukias NM, Popel AS. A model of nitric oxide capillary exchange. Microcirculation (New York, N.Y. : 1994). 10: 479-95. PMID 14745461 DOI: 10.1038/sj.mn.7800210  0.56
2003 Kavdia M, Popel AS. Wall shear stress differentially affects NO level in arterioles for volume expanders and Hb-based O2 carriers. Microvascular Research. 66: 49-58. PMID 12826074 DOI: 10.1016/S0026-2862(03)00008-6  0.56
2003 Spector AA, Brownell WE, Popel AS. Effect of outer hair cell piezoelectricity on high-frequency receptor potentials. The Journal of the Acoustical Society of America. 113: 453-61. PMID 12558282 DOI: 10.1121/1.1526493  0.56
2002 Kavdia M, Pittman RN, Popel AS. Theoretical analysis of effects of blood substitute affinity and cooperativity on organ oxygen transport. Journal of Applied Physiology (Bethesda, Md. : 1985). 93: 2122-8. PMID 12391075 DOI: 10.1152/japplphysiol.00676.2002  0.56
2002 Tsoukias NM, Popel AS. Erythrocyte consumption of nitric oxide in presence and absence of plasma-based hemoglobin. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2265-77. PMID 12003837 DOI: 10.1152/ajpheart.01080.2001  0.56
2002 Kavdia M, Tsoukias NM, Popel AS. Model of nitric oxide diffusion in an arteriole: impact of hemoglobin-based blood substitutes. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2245-53. PMID 12003834 DOI: 10.1152/ajpheart.00972.2001  0.56
2002 Spector AA, Ameen M, Charalambides PG, Popel AS. Nanostructure, effective properties, and deformation pattern of the cochlear outer hair cell cytoskeleton. Journal of Biomechanical Engineering. 124: 180-7. PMID 12002127 DOI: 10.1115/1.1448521  0.56
2002 Wootton DM, Popel AS, Alevriadou BR. An experimental and theoretical study on the dissolution of mural fibrin clots by tissue-type plasminogen activator. Biotechnology and Bioengineering. 77: 405-19. PMID 11787013 DOI: 10.1002/bit.10127  0.56
Show low-probability matches.