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Alex Sigal, Ph.D. - Publications

Affiliations: 
2005 Weizmann Institute of Science, Rehovot, Israel 
Area:
Cell Biology, General Biophysics
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Moyano A, Lustig G, Rodel HE, Antal T, Sigal A. Interference with HIV infection of the first cell is essential for viral clearance at sub-optimal levels of drug inhibition. Plos Computational Biology. 16: e1007482. PMID 32017770 DOI: 10.1371/Journal.Pcbi.1007482  0.308
2019 Cromarty R, Sigal A, Liebenberg LJP, McKinnon LR, Abdool Karim SS, Passmore JS, Archary D. Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated Model. Frontiers in Immunology. 10: 1705. PMID 31396221 DOI: 10.3389/Fimmu.2019.01705  0.31
2018 Barichievy S, Naidoo J, Boullé M, Scholefield J, Parihar SP, Coussens AK, Brombacher F, Sigal A, Mhlanga MM. Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA. Frontiers in Cellular and Infection Microbiology. 8: 263. PMID 30123777 DOI: 10.3389/Fcimb.2018.00263  0.381
2018 Jackson L, Hunter J, Cele S, Ferreira IM, Young AC, Karim F, Madansein R, Dullabh KJ, Chen CY, Buckels NJ, Ganga Y, Khan K, Boulle M, Lustig G, Neher RA, ... Sigal A, et al. Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death. Elife. 7. PMID 29555018 DOI: 10.7554/Elife.30134  0.367
2018 Kim JT, Chang E, Sigal A, Baltimore D. Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner. Plos One. 13: e0189945. PMID 29293546 DOI: 10.1371/Journal.Pone.0189945  0.389
2017 Mahamed D, Boulle M, Ganga Y, Mc Arthur C, Skroch S, Oom L, Catinas O, Pillay K, Naicker M, Rampersad S, Mathonsi C, Hunter J, Sreejit G, Pym AS, Lustig G, ... Sigal A, et al. Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. Elife. 6. PMID 28130921 DOI: 10.7554/Elife.22028  0.368
2017 Jackson L, Hunter J, Cele S, Ferreira IM, Young AC, Karim F, Madansein R, Dullabh KJ, Chen C, Buckels NJ, Ganga Y, Khan K, Boulle M, Lustig G, Neher RA, ... Sigal A, et al. Author response: Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death Elife. DOI: 10.7554/Elife.30134.040  0.319
2016 Boullé M, Müller TG, Dähling S, Ganga Y, Jackson L, Mahamed D, Oom L, Lustig G, Neher RA, Sigal A. HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell. Plos Pathogens. 12: e1005964. PMID 27812216 DOI: 10.1371/Journal.Ppat.1005964  0.46
2014 Farkash-Amar S, Zimmer A, Eden E, Cohen A, Geva-Zatorsky N, Cohen L, Milo R, Sigal A, Danon T, Alon U. Noise genetics: inferring protein function by correlating phenotype with protein levels and localization in individual human cells. Plos Genetics. 10: e1004176. PMID 24603725 DOI: 10.1371/Journal.Pgen.1004176  0.644
2012 Farkash-Amar S, Eden E, Cohen A, Geva-Zatorsky N, Cohen L, Milo R, Sigal A, Danon T, Alon U. Dynamic proteomics of human protein level and localization across the cell cycle. Plos One. 7: e48722. PMID 23144944 DOI: 10.1371/Journal.Pone.0048722  0.701
2012 Sigal A, Baltimore D. As good as it gets? The problem of HIV persistence despite antiretroviral drugs. Cell Host & Microbe. 12: 132-8. PMID 22901535 DOI: 10.1016/J.Chom.2012.07.005  0.324
2012 Puliafito A, Hufnagel L, Neveu P, Streichan S, Sigal A, Fygenson DK, Shraiman BI. Collective and single cell behavior in epithelial contact inhibition. Proceedings of the National Academy of Sciences of the United States of America. 109: 739-44. PMID 22228306 DOI: 10.1073/Pnas.1007809109  0.496
2011 Sigal A, Kim JT, Balazs AB, Dekel E, Mayo A, Milo R, Baltimore D. Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy. Nature. 477: 95-8. PMID 21849975 DOI: 10.1038/Nature10347  0.404
2010 Frenkel-Morgenstern M, Cohen AA, Geva-Zatorsky N, Eden E, Prilusky J, Issaeva I, Sigal A, Cohen-Saidon C, Liron Y, Cohen L, Danon T, Perzov N, Alon U. Dynamic Proteomics: a database for dynamics and localizations of endogenous fluorescently-tagged proteins in living human cells. Nucleic Acids Research. 38: D508-12. PMID 19820112 DOI: 10.1093/Nar/Gkp808  0.649
2009 Cohen-Saidon C, Cohen AA, Sigal A, Liron Y, Alon U. Dynamics and variability of ERK2 response to EGF in individual living cells. Molecular Cell. 36: 885-93. PMID 20005850 DOI: 10.1016/J.Molcel.2009.11.025  0.665
2009 Cohen AA, Kalisky T, Mayo A, Geva-Zatorsky N, Danon T, Issaeva I, Kopito RB, Perzov N, Milo R, Sigal A, Alon U. Protein dynamics in individual human cells: experiment and theory. Plos One. 4: e4901. PMID 19381343 DOI: 10.1371/Journal.Pone.0004901  0.702
2008 Cohen AA, Geva-Zatorsky N, Eden E, Frenkel-Morgenstern M, Issaeva I, Sigal A, Milo R, Cohen-Saidon C, Liron Y, Kam Z, Cohen L, Danon T, Perzov N, Alon U. Dynamic proteomics of individual cancer cells in response to a drug. Science (New York, N.Y.). 322: 1511-6. PMID 19023046 DOI: 10.1126/Science.1160165  0.66
2007 Sigal A, Danon T, Cohen A, Milo R, Geva-Zatorsky N, Lustig G, Liron Y, Alon U, Perzov N. Generation of a fluorescently labeled endogenous protein library in living human cells. Nature Protocols. 2: 1515-27. PMID 17571059 DOI: 10.1038/Nprot.2007.197  0.647
2006 Sigal A, Milo R, Cohen A, Geva-Zatorsky N, Klein Y, Liron Y, Rosenfeld N, Danon T, Perzov N, Alon U. Variability and memory of protein levels in human cells. Nature. 444: 643-6. PMID 17122776 DOI: 10.1038/Nature05316  0.736
2006 Sigal A, Milo R, Cohen A, Geva-Zatorsky N, Klein Y, Alaluf I, Swerdlin N, Perzov N, Danon T, Liron Y, Raveh T, Carpenter AE, Lahav G, Alon U. Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nature Methods. 3: 525-31. PMID 16791210 DOI: 10.1038/Nmeth892  0.754
2006 Geva-Zatorsky N, Rosenfeld N, Itzkovitz S, Milo R, Sigal A, Dekel E, Yarnitzky T, Liron Y, Polak P, Lahav G, Alon U. Oscillations and variability in the p53 system. Molecular Systems Biology. 2: 2006.0033. PMID 16773083 DOI: 10.1038/Msb4100068  0.732
2004 Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nature Genetics. 36: 147-50. PMID 14730303 DOI: 10.1038/Ng1293  0.71
2001 Sigal A, Matas D, Almog N, Goldfinger N, Rotter V. The C-terminus of mutant p53 is necessary for its ability to interfere with growth arrest or apoptosis. Oncogene. 20: 4891-8. PMID 11521201 DOI: 10.1038/Sj.Onc.1204724  0.339
2001 Seluanov A, Gorbunova V, Falcovitz A, Sigal A, Milyavsky M, Zurer I, Shohat G, Goldfinger N, Rotter V. Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53. Molecular and Cellular Biology. 21: 1552-64. PMID 11238892 DOI: 10.1128/Mcb.21.5.1552-1564.2001  0.38
2000 Sigal A, Bleijs DA, Grabovsky V, van Vliet SJ, Dwir O, Figdor CG, van Kooyk Y, Alon R. The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment. Journal of Immunology (Baltimore, Md. : 1950). 165: 442-52. PMID 10861083 DOI: 10.4049/Jimmunol.165.1.442  0.305
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