Alex Sigal, Ph.D. - Publications

Affiliations: 
2005 Weizmann Institute of Science, Rehovot, Israel 
Area:
Cell Biology, General Biophysics

42/44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Snyman J, Hwa SH, Krause R, Muema D, Reddy T, Ganga Y, Karim F, Leslie A, Sigal A, Ndung'u T. Similar antibody responses against SARS-CoV-2 in HIV uninfected and infected individuals on antiretroviral therapy during the first South African infection wave. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34472583 DOI: 10.1093/cid/ciab758  1
2021 Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB. Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Cell. 184: 2523. PMID 33930298 DOI: 10.1016/j.cell.2021.04.006  1
2021 Cele S, Gazy I, Jackson L, Hwa SH, Tegally H, Lustig G, Giandhari J, Pillay S, Wilkinson E, Naidoo Y, Karim F, Ganga Y, Khan K, Bernstein M, Balazs AB, ... ... Sigal A, et al. Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma. Nature. PMID 33780970 DOI: 10.1038/s41586-021-03471-w  1
2021 Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB. Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Cell. PMID 33743213 DOI: 10.1016/j.cell.2021.03.013  1
2021 Madhi SA, Baillie V, Cutland CL, Voysey M, Koen AL, Fairlie L, Padayachee SD, Dheda K, Barnabas SL, Bhorat QE, Briner C, Kwatra G, Ahmed K, Aley P, Bhikha S, ... ... Sigal A, et al. Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant. The New England Journal of Medicine. PMID 33725432 DOI: 10.1056/NEJMoa2102214  1
2021 Tegally H, Wilkinson E, Giovanetti M, Iranzadeh A, Fonseca V, Giandhari J, Doolabh D, Pillay S, San EJ, Msomi N, Mlisana K, von Gottberg A, Walaza S, Allam M, Ismail A, ... ... Sigal A, et al. Emergence of a SARS-CoV-2 variant of concern with mutations in spike glycoprotein. Nature. PMID 33690265 DOI: 10.1038/s41586-021-03402-9  1
2021 Garcia-Beltran WF, Lam EC, Denis KS, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB. Circulating SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Medrxiv : the Preprint Server For Health Sciences. PMID 33619506 DOI: 10.1101/2021.02.14.21251704  1
2021 Tegally H, Wilkinson E, Lessells RJ, Giandhari J, Pillay S, Msomi N, Mlisana K, Bhiman JN, von Gottberg A, Walaza S, Fonseca V, Allam M, Ismail A, Glass AJ, Engelbrecht S, ... ... Sigal A, et al. Sixteen novel lineages of SARS-CoV-2 in South Africa. Nature Medicine. PMID 33531709 DOI: 10.1038/s41591-021-01255-3  1
2020 Naicker N, Sigal A, Naidoo K. Metformin as Host-Directed Therapy for TB Treatment: Scoping Review. Frontiers in Microbiology. 11: 435. PMID 32411100 DOI: 10.3389/Fmicb.2020.00435  0.01
2020 Moyano A, Lustig G, Rodel HE, Antal T, Sigal A. Interference with HIV infection of the first cell is essential for viral clearance at sub-optimal levels of drug inhibition. Plos Computational Biology. 16: e1007482. PMID 32017770 DOI: 10.1371/Journal.Pcbi.1007482  1
2019 Cromarty R, Sigal A, Liebenberg LJP, McKinnon LR, Abdool Karim SS, Passmore JS, Archary D. Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated Model. Frontiers in Immunology. 10: 1705. PMID 31396221 DOI: 10.3389/Fimmu.2019.01705  0.01
2018 Barichievy S, Naidoo J, Boullé M, Scholefield J, Parihar SP, Coussens AK, Brombacher F, Sigal A, Mhlanga MM. Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA. Frontiers in Cellular and Infection Microbiology. 8: 263. PMID 30123777 DOI: 10.3389/Fcimb.2018.00263  1
2018 Jackson L, Hunter J, Cele S, Ferreira IM, Young AC, Karim F, Madansein R, Dullabh KJ, Chen CY, Buckels NJ, Ganga Y, Khan K, Boulle M, Lustig G, Neher RA, ... Sigal A, et al. Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death. Elife. 7. PMID 29555018 DOI: 10.7554/Elife.30134  1
2018 Kim JT, Chang E, Sigal A, Baltimore D. Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner. Plos One. 13: e0189945. PMID 29293546 DOI: 10.1371/Journal.Pone.0189945  1
2017 Mahamed D, Boulle M, Ganga Y, Mc Arthur C, Skroch S, Oom L, Catinas O, Pillay K, Naicker M, Rampersad S, Mathonsi C, Hunter J, Wong EB, Suleman M, Sreejit G, ... ... Sigal A, et al. Correction: Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. Elife. 6. PMID 28475039 DOI: 10.7554/eLife.28205  1
2017 Mahamed D, Boulle M, Ganga Y, Mc Arthur C, Skroch S, Oom L, Catinas O, Pillay K, Naicker M, Rampersad S, Mathonsi C, Hunter J, Sreejit G, Pym AS, Lustig G, ... Sigal A, et al. Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. Elife. 6. PMID 28130921 DOI: 10.7554/Elife.22028  1
2017 Jackson L, Hunter J, Cele S, Ferreira IM, Young AC, Karim F, Madansein R, Dullabh KJ, Chen C, Buckels NJ, Ganga Y, Khan K, Boulle M, Lustig G, Neher RA, ... Sigal A, et al. Author response: Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death Elife. DOI: 10.7554/Elife.30134.040  1
2016 Boullé M, Müller TG, Dähling S, Ganga Y, Jackson L, Mahamed D, Oom L, Lustig G, Neher RA, Sigal A. HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell. Plos Pathogens. 12: e1005964. PMID 27812216 DOI: 10.1371/Journal.Ppat.1005964  1
2014 Costiniuk CT, Sigal A, Jenabian MA, Nijs P, Wilson D. Short communication: Lower baseline CD4 count is associated with a greater propensity toward virological failure in a cohort of South African HIV patients. Aids Research and Human Retroviruses. 30: 531-4. PMID 24803320 DOI: 10.1089/Aid.2014.0011  1
2014 Farkash-Amar S, Zimmer A, Eden E, Cohen A, Geva-Zatorsky N, Cohen L, Milo R, Sigal A, Danon T, Alon U. Noise genetics: inferring protein function by correlating phenotype with protein levels and localization in individual human cells. Plos Genetics. 10: e1004176. PMID 24603725 DOI: 10.1371/Journal.Pgen.1004176  1
2012 Farkash-Amar S, Eden E, Cohen A, Geva-Zatorsky N, Cohen L, Milo R, Sigal A, Danon T, Alon U. Dynamic proteomics of human protein level and localization across the cell cycle. Plos One. 7: e48722. PMID 23144944 DOI: 10.1371/Journal.Pone.0048722  1
2012 Sigal A, Baltimore D. As good as it gets? The problem of HIV persistence despite antiretroviral drugs. Cell Host & Microbe. 12: 132-8. PMID 22901535 DOI: 10.1016/J.Chom.2012.07.005  1
2012 Puliafito A, Hufnagel L, Neveu P, Streichan S, Sigal A, Fygenson DK, Shraiman BI. Collective and single cell behavior in epithelial contact inhibition. Proceedings of the National Academy of Sciences of the United States of America. 109: 739-44. PMID 22228306 DOI: 10.1073/Pnas.1007809109  1
2012 Ulmansky R, Turjeman K, Baru M, Katzavian G, Harel M, Sigal A, Naparstek Y, Barenholz Y. Glucocorticoids in nano-liposomes administered intravenously and subcutaneously to adjuvant arthritis rats are superior to the free drugs in suppressing arthritis and inflammatory cytokines. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 299-305. PMID 22226777 DOI: 10.1016/j.jconrel.2011.12.024  1
2011 Avnir Y, Turjeman K, Tulchinsky D, Sigal A, Kizelsztein P, Tzemach D, Gabizon A, Barenholz Y. Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids. Plos One. 6: e25721. PMID 21998684 DOI: 10.1371/journal.pone.0025721  1
2011 Sigal A, Kim JT, Balazs AB, Dekel E, Mayo A, Milo R, Baltimore D. Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy. Nature. 477: 95-8. PMID 21849975 DOI: 10.1038/Nature10347  1
2010 Frenkel-Morgenstern M, Cohen AA, Geva-Zatorsky N, Eden E, Prilusky J, Issaeva I, Sigal A, Cohen-Saidon C, Liron Y, Cohen L, Danon T, Perzov N, Alon U. Dynamic Proteomics: a database for dynamics and localizations of endogenous fluorescently-tagged proteins in living human cells. Nucleic Acids Research. 38: D508-12. PMID 19820112 DOI: 10.1093/Nar/Gkp808  1
2009 Cohen-Saidon C, Cohen AA, Sigal A, Liron Y, Alon U. Dynamics and variability of ERK2 response to EGF in individual living cells. Molecular Cell. 36: 885-93. PMID 20005850 DOI: 10.1016/J.Molcel.2009.11.025  1
2009 Kizelsztein P, Ovadia H, Garbuzenko O, Sigal A, Barenholz Y. Pegylated nanoliposomes remote-loaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 213: 20-5. PMID 19564052 DOI: 10.1016/J.Jneuroim.2009.05.019  1
2009 Cohen AA, Kalisky T, Mayo A, Geva-Zatorsky N, Danon T, Issaeva I, Kopito RB, Perzov N, Milo R, Sigal A, Alon U. Protein dynamics in individual human cells: experiment and theory. Plos One. 4: e4901. PMID 19381343 DOI: 10.1371/Journal.Pone.0004901  1
2008 Cohen AA, Geva-Zatorsky N, Eden E, Frenkel-Morgenstern M, Issaeva I, Sigal A, Milo R, Cohen-Saidon C, Liron Y, Kam Z, Cohen L, Danon T, Perzov N, Alon U. Dynamic proteomics of individual cancer cells in response to a drug. Science (New York, N.Y.). 322: 1511-6. PMID 19023046 DOI: 10.1126/Science.1160165  1
2008 Schroeder A, Sigal A, Turjeman K, Barenholz Y. Using PEGylated nano-liposomes to target tissue invaded by a foreign body. Journal of Drug Targeting. 16: 591-5. PMID 18686129 DOI: 10.1080/10611860802228939  1
2007 Sigal A, Danon T, Cohen A, Milo R, Geva-Zatorsky N, Lustig G, Liron Y, Alon U, Perzov N. Generation of a fluorescently labeled endogenous protein library in living human cells. Nature Protocols. 2: 1515-27. PMID 17571059 DOI: 10.1038/Nprot.2007.197  1
2007 Lavelle C, Sigal A. Systems biology meets chromatin function: a report on the Fourth Elmau Conference on Nuclear Organization. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 15: 247-56. PMID 17279452 DOI: 10.1007/S10577-006-1118-6  1
2006 Sigal A, Milo R, Cohen A, Geva-Zatorsky N, Klein Y, Liron Y, Rosenfeld N, Danon T, Perzov N, Alon U. Variability and memory of protein levels in human cells. Nature. 444: 643-6. PMID 17122776 DOI: 10.1038/Nature05316  1
2006 Sigal A, Milo R, Cohen A, Geva-Zatorsky N, Klein Y, Alaluf I, Swerdlin N, Perzov N, Danon T, Liron Y, Raveh T, Carpenter AE, Lahav G, Alon U. Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nature Methods. 3: 525-31. PMID 16791210 DOI: 10.1038/Nmeth892  1
2006 Geva-Zatorsky N, Rosenfeld N, Itzkovitz S, Milo R, Sigal A, Dekel E, Yarnitzky T, Liron Y, Polak P, Lahav G, Alon U. Oscillations and variability in the p53 system. Molecular Systems Biology. 2: 2006.0033. PMID 16773083 DOI: 10.1038/Msb4100068  1
2004 Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nature Genetics. 36: 147-50. PMID 14730303 DOI: 10.1038/Ng1293  1
2001 Sigal A, Matas D, Almog N, Goldfinger N, Rotter V. The C-terminus of mutant p53 is necessary for its ability to interfere with growth arrest or apoptosis. Oncogene. 20: 4891-8. PMID 11521201 DOI: 10.1038/Sj.Onc.1204724  1
2001 Matas D, Sigal A, Stambolsky P, Milyavsky M, Weisz L, Schwartz D, Goldfinger N, Rotter V. Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis. The Embo Journal. 20: 4163-72. PMID 11483519 DOI: 10.1093/Emboj/20.15.4163  1
2001 Seluanov A, Gorbunova V, Falcovitz A, Sigal A, Milyavsky M, Zurer I, Shohat G, Goldfinger N, Rotter V. Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53. Molecular and Cellular Biology. 21: 1552-64. PMID 11238892 DOI: 10.1128/Mcb.21.5.1552-1564.2001  1
2000 Sigal A, Bleijs DA, Grabovsky V, van Vliet SJ, Dwir O, Figdor CG, van Kooyk Y, Alon R. The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment. Journal of Immunology (Baltimore, Md. : 1950). 165: 442-52. PMID 10861083 DOI: 10.4049/Jimmunol.165.1.442  1
Low-probability matches
2021 Skelly DT, Harding AC, Gilbert-Jaramillo J, Knight ML, Longet S, Brown A, Adele S, Adland E, Brown H, Tipton T, Stafford L, Mentzer AJ, Johnson SA, Amini A, ... ... Sigal A, et al. Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern. Nature Communications. 12: 5061. PMID 34404775 DOI: 10.1038/s41467-021-25167-5  0.01
2021 Faulkner N, Ng KW, Wu MY, Harvey R, Margaritis M, Paraskevopoulou S, Houlihan C, Hussain S, Greco M, Bolland W, Warchal S, Heaney J, Rickman H, Spyer M, Frampton D, ... ... Sigal A, et al. Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains. Elife. 10. PMID 34323691 DOI: 10.7554/eLife.69317  0.01
Hide low-probability matches.