Year |
Citation |
Score |
2020 |
Matoori S, Forster V, Agostoni V, Bettschart-Wolfensberger R, Bektas RN, Thöny B, Häberle J, Leroux JC, Kabbaj M. Preclinical evaluation of liposome-supported peritoneal dialysis for the treatment of hyperammonemic crises. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32860926 DOI: 10.1016/J.Jconrel.2020.08.040 |
0.317 |
|
2020 |
Schmidt AC, Hebels ER, Weitzel C, Kletzmayr A, Bao Y, Steuer C, Leroux JC. Engineered Polymersomes for the Treatment of Fish Odor Syndrome: A First Randomized Double Blind Olfactory Study. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1903697. PMID 32328434 DOI: 10.1002/Advs.201903697 |
0.344 |
|
2020 |
Schmidt AC, Hebels ER, Weitzel C, Stoessel B, Bao Y, Altmann KH, Leroux JC. Ammonia uptake by transmembrane pH gradient poly(isoprene)-block-poly(ethylene glycol) polymersomes. Soft Matter. PMID 32115597 DOI: 10.1039/D0Sm00183J |
0.397 |
|
2020 |
Pereira de Sousa I, Gourmel C, Berkovska O, Burger M, Leroux JC. A microparticulate based formulation to protect therapeutic enzymes from proteolytic digestion: phenylalanine ammonia lyase as case study. Scientific Reports. 10: 3651. PMID 32107425 DOI: 10.1038/S41598-020-60463-Y |
0.304 |
|
2020 |
Matoori S, Leroux J. Twenty-five years of polymersomes: lost in translation? Materials Horizons. 7: 1297-1309. DOI: 10.1039/C9Mh01669D |
0.33 |
|
2019 |
Matoori S, Bao Y, Schmidt A, Fischer EJ, Ochoa-Sanchez R, Tremblay M, Oliveira MM, Rose CF, Leroux JC. An Investigation of PS-b-PEO Polymersomes for the Oral Treatment and Diagnosis of Hyperammonemia. Small (Weinheim An Der Bergstrasse, Germany). e1902347. PMID 31721441 DOI: 10.1002/Smll.201902347 |
0.362 |
|
2019 |
Bisso S, Mura S, Castagner B, Couvreur P, Leroux JC. Dual delivery of nucleic acids and PEGylated-bisphosphonates via calcium phosphate nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 31220571 DOI: 10.1016/J.Ejpb.2019.06.013 |
0.319 |
|
2018 |
Tiefenboeck P, Kim JA, Leroux JC. Intracellular delivery of colloids: Past and future contributions from microinjection. Advanced Drug Delivery Reviews. PMID 29935217 DOI: 10.1016/J.Addr.2018.06.013 |
0.32 |
|
2018 |
Signorell RD, Luciani P, Brambilla D, Leroux JC. Pharmacokinetics of Lipid-Drug Conjugates Loaded into Liposomes. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29678733 DOI: 10.1016/J.Ejpb.2018.04.003 |
0.349 |
|
2018 |
Giacalone G, Matoori S, Agostoni V, Forster V, Kabbaj M, Eggenschwiler S, Lussi M, De Gottardi A, Zamboni N, Leroux JC. Liposome-supported peritoneal dialysis in the treatment of severe hyperammonemia: An investigation on potential interactions. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29601930 DOI: 10.1016/J.Jconrel.2018.03.030 |
0.314 |
|
2017 |
Signorell RD, Papachristodoulou A, Xiao J, Arpagaus B, Casalini T, Grandjean J, Thamm J, Steiniger F, Luciani P, Brambilla D, Werner B, Martin E, Weller M, Roth P, Leroux JC. Preparation of PEGylated liposomes incorporating lipophilic lomeguatrib derivatives for the sensitization of chemo-resistant gliomas. International Journal of Pharmaceutics. 536: 388-396. PMID 29198811 DOI: 10.1016/J.Ijpharm.2017.11.070 |
0.35 |
|
2017 |
Leroux JC. Drug Delivery: Too Much Complexity, Not Enough Reproducibility? Angewandte Chemie (International Ed. in English). PMID 28967701 DOI: 10.1002/Anie.201709002 |
0.332 |
|
2017 |
Huang X, Andina D, Ge J, Labarre A, Leroux JC, Castagner B. Characterization of calcium phosphate nanoparticles based on a PEGylated chelator for gene delivery. Acs Applied Materials & Interfaces. PMID 28266206 DOI: 10.1021/Acsami.6B15925 |
0.3 |
|
2017 |
Bertrand N, Simard P, Leroux JC. Serum-Stable, Long-Circulating, pH-Sensitive PEGylated Liposomes. Methods in Molecular Biology (Clifton, N.J.). 1522: 193-207. PMID 27837540 DOI: 10.1007/978-1-4939-6591-5_15 |
0.668 |
|
2017 |
Giacalone G, Forster V, Agostoni V, Kabbaj M, Zamboni N, Leroux J. Drugs Interactions and Metabolomic Profile During Liposome-Supported Peritoneal Dialysis (LSPD) in the Treatment of Severe Hyperammonemia Journal of Clinical and Experimental Hepatology. 7. DOI: 10.1016/J.Jceh.2017.01.020 |
0.301 |
|
2017 |
Leroux J. Editorial: Drug Delivery: zu kompliziert und nicht reproduzierbar genug? Angewandte Chemie. 129: 15368-15369. DOI: 10.1002/Ange.201709002 |
0.324 |
|
2016 |
Polomska A, Gauthier MA, Leroux JC. In Vitro and In Vivo Evaluation of PEGylated Layer-by-Layer Polyelectrolyte-Coated Paclitaxel Nanocrystals. Small (Weinheim An Der Bergstrasse, Germany). PMID 27748999 DOI: 10.1002/Smll.201602066 |
0.308 |
|
2016 |
Moroz E, Lee SH, Yamada K, Halloy F, Martínez-Montero S, Jahns H, Hall J, Damha MJ, Castagner B, Leroux JC. Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells. Molecular Therapy. Nucleic Acids. 5: e364. PMID 27648924 DOI: 10.1038/Mtna.2016.69 |
0.32 |
|
2016 |
Polomska A, Leroux JC, Brambilla D. Layer-by-Layer Coating of Solid Drug Cores: A Versatile Method to Improve Stability, Control Release and Tune Surface Properties. Macromolecular Bioscience. PMID 27569374 DOI: 10.1002/Mabi.201600228 |
0.303 |
|
2016 |
Kim H, Okamoto H, Felber AE, Polomska A, Morone N, Heuser JE, Leroux JC, Murakami T. Polymer-coated pH-responsive high-density lipoproteins. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26959846 DOI: 10.1016/J.Jconrel.2016.03.005 |
0.427 |
|
2016 |
Fuhrmann G, Grotzky A, Lukić R, Matoori S, Luciani P, Yu H, Zhang B, Walde P, Schlüter AD, Gauthier MA, Leroux JC. Corrigendum: Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates. Nature Chemistry. 8: 281. PMID 26892564 DOI: 10.1038/Nchem.2458 |
0.318 |
|
2016 |
Moroz E, Matoori S, Leroux JC. Oral delivery of macromolecular drugs: Where we are after almost 100years of attempts. Advanced Drug Delivery Reviews. PMID 26826437 DOI: 10.1016/J.Addr.2016.01.010 |
0.329 |
|
2016 |
Agostoni V, Lee SH, Forster V, Kabbaj M, Bosoi CR, Tremblay M, Zadory M, Rose CF, Leroux J. Liposome-Supported Peritoneal Dialysis for the Treatment of Hyperammonemia-Associated Encephalopathy Advanced Functional Materials. 26: 8382-8389. DOI: 10.1002/Adfm.201603519 |
0.323 |
|
2015 |
Sun T, Morger A, Castagner B, Leroux JC. Oral prodrug strategy for poorly soluble drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 213: e102. PMID 27005028 DOI: 10.1016/J.Jconrel.2015.05.171 |
0.315 |
|
2015 |
Schulz JD, Patt M, Basler S, Kries H, Hilvert D, Gauthier MA, Leroux JC. Site-Specific Polymer Conjugation Stabilizes Therapeutic Enzymes in the Gastrointestinal Tract. Advanced Materials (Deerfield Beach, Fla.). PMID 26640034 DOI: 10.1002/Adma.201504797 |
0.315 |
|
2015 |
Schulz JD, Gauthier MA, Leroux JC. Improving oral drug bioavailability with polycations? European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 97: 427-37. PMID 26614561 DOI: 10.1016/J.Ejpb.2015.04.025 |
0.384 |
|
2015 |
Sun T, Morger A, Castagner B, Leroux JC. An oral redox-sensitive self-immolating prodrug strategy. Chemical Communications (Cambridge, England). 51: 5721-4. PMID 25719505 DOI: 10.1039/C5Cc00405E |
0.341 |
|
2015 |
Karfeld-Sulzer LS, Ghayor C, Siegenthaler B, de Wild M, Leroux JC, Weber FE. N-methyl pyrrolidone/bone morphogenetic protein-2 double delivery with in situ forming implants. Journal of Controlled Release : Official Journal of the Controlled Release Society. 203: 181-8. PMID 25697800 DOI: 10.1016/J.Jconrel.2015.02.019 |
0.301 |
|
2015 |
Gong Y, Leroux JC, Gauthier MA. Releasable Conjugation of Polymers to Proteins. Bioconjugate Chemistry. 26: 1172-81. PMID 25612877 DOI: 10.1021/Bc500611K |
0.35 |
|
2015 |
Klein PM, Müller K, Gutmann C, Kos P, Krhac Levacic A, Edinger D, Höhn M, Leroux JC, Gauthier MA, Wagner E. Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 205: 109-19. PMID 25553827 DOI: 10.1016/J.Jconrel.2014.12.035 |
0.309 |
|
2015 |
Kovacs Z, Luciani P, Roth P, Leroux J, Martin E, Werner B. Blood-brain barrier opening-based local delivery of 80 nm-sized liposomes in mice using pulsed focused ultrasound Journal of Therapeutic Ultrasound. 3: 24. DOI: 10.1186/2050-5736-3-S1-P24 |
0.312 |
|
2015 |
Liu M, Leroux J, Gauthier MA. Conformation–function relationships for the comb-shaped polymer pOEGMA Progress in Polymer Science. 48: 111-121. DOI: 10.1016/J.Progpolymsci.2015.03.001 |
0.355 |
|
2014 |
Liu M, Johansen P, Zabel F, Leroux JC, Gauthier MA. Semi-permeable coatings fabricated from comb-polymers efficiently protect proteins in vivo. Nature Communications. 5: 5526. PMID 25407758 DOI: 10.1038/Ncomms6526 |
0.334 |
|
2014 |
Forster V, Signorell RD, Roveri M, Leroux JC. Liposome-supported peritoneal dialysis for detoxification of drugs and endogenous metabolites. Science Translational Medicine. 6: 258ra141. PMID 25320233 DOI: 10.1126/Scitranslmed.3009135 |
0.346 |
|
2014 |
Brülisauer L, Gauthier MA, Leroux JC. Disulfide-containing parenteral delivery systems and their redox-biological fate. Journal of Controlled Release : Official Journal of the Controlled Release Society. 195: 147-54. PMID 24952369 DOI: 10.1016/J.Jconrel.2014.06.012 |
0.371 |
|
2014 |
Fuhrmann K, Gauthier MA, Leroux JC. Targeting of injectable drug nanocrystals. Molecular Pharmaceutics. 11: 1762-71. PMID 24766270 DOI: 10.1021/Mp5001247 |
0.334 |
|
2014 |
Buerkli C, Lee SH, Moroz E, Stuparu MC, Leroux JC, Khan A. Amphipathic homopolymers for siRNA delivery: probing impact of bifunctional polymer composition on transfection. Biomacromolecules. 15: 1707-15. PMID 24754338 DOI: 10.1021/Bm5001197 |
0.356 |
|
2013 |
Fuhrmann K, Połomska A, Aeberli C, Castagner B, Gauthier MA, Leroux JC. Modular design of redox-responsive stabilizers for nanocrystals. Acs Nano. 7: 8243-50. PMID 23968310 DOI: 10.1021/Nn4037317 |
0.346 |
|
2013 |
Lee SH, Castagner B, Leroux JC. Is there a future for cell-penetrating peptides in oligonucleotide delivery? European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 85: 5-11. PMID 23958313 DOI: 10.1016/J.Ejpb.2013.03.021 |
0.306 |
|
2013 |
Fuhrmann G, Grotzky A, Lukić R, Matoori S, Luciani P, Yu H, Zhang B, Walde P, Schlüter AD, Gauthier MA, Leroux JC. Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates Nature Chemistry. 5: 582-589. PMID 23787748 DOI: 10.1038/Nchem.1675 |
0.315 |
|
2013 |
Wu C, Wang S, Brülisauer L, Leroux JC, Gauthier MA. Broad control of disulfide stability through microenvironmental effects and analysis in complex redox environments. Biomacromolecules. 14: 2383-8. PMID 23738500 DOI: 10.1021/Bm400501C |
0.349 |
|
2013 |
Proulx ST, Luciani P, Dieterich LC, Karaman S, Leroux JC, Detmar M. Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 550-7. PMID 23665257 DOI: 10.1016/J.Jconrel.2013.04.027 |
0.302 |
|
2013 |
Giger EV, Castagner B, Räikkönen J, Mönkkönen J, Leroux JC. siRNA transfection with calcium phosphate nanoparticles stabilized with PEGylated chelators. Advanced Healthcare Materials. 2: 134-44. PMID 23184402 DOI: 10.1002/Adhm.201200088 |
0.313 |
|
2013 |
Fuhrmann G, Gauthier MA, Leroux J. Polymer–Enzyme Conjugates for Oral Drug Delivery Applications Chimia. 67: 685-685. DOI: 10.2533/Chimia.2013.685 |
0.334 |
|
2013 |
Liu M, Tirino P, Radivojevic M, Phillips DJ, Gibson MI, Leroux JC, Gauthier MA. Molecular sieving on the surface of a protein provides protection without loss of activity Advanced Functional Materials. 23: 2007-2015. DOI: 10.1002/Adfm.201202227 |
0.332 |
|
2012 |
Brülisauer L, Kathriner N, Prenrecaj M, Gauthier MA, Leroux JC. Tracking the bioreduction of disulfide-containing cationic dendrimers. Angewandte Chemie (International Ed. in English). 51: 12454-8. PMID 23129324 DOI: 10.1002/Anie.201207070 |
0.339 |
|
2012 |
Felber AE, Bayó-Puxan N, Deleavey GF, Castagner B, Damha MJ, Leroux JC. The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity. Biomaterials. 33: 5955-65. PMID 22656448 DOI: 10.1016/J.Biomaterials.2012.05.019 |
0.333 |
|
2012 |
Dufresne MH, Marouf E, Kränzlin Y, Gauthier MA, Leroux JC. Lipase is essential for the study of in vitro release kinetics from organogels. Molecular Pharmaceutics. 9: 1803-11. PMID 22510056 DOI: 10.1021/Mp3001099 |
0.365 |
|
2012 |
Forster V, Luciani P, Leroux JC. Treatment of calcium channel blocker-induced cardiovascular toxicity with drug scavenging liposomes. Biomaterials. 33: 3578-85. PMID 22330848 DOI: 10.1016/J.Biomaterials.2012.01.042 |
0.36 |
|
2012 |
Fuhrmann K, Schulz JD, Gauthier MA, Leroux JC. PEG nanocages as non-sheddable stabilizers for drug nanocrystals. Acs Nano. 6: 1667-76. PMID 22296103 DOI: 10.1021/Nn2046554 |
0.356 |
|
2012 |
Pinier M, Fuhrmann G, Galipeau HJ, Rivard N, Murray JA, David CS, Drasarova H, Tuckova L, Leroux JC, Verdu EF. The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues. Gastroenterology. 142: 316-25.e1-12. PMID 22079593 DOI: 10.1053/J.Gastro.2011.10.038 |
0.765 |
|
2012 |
Bertrand N, Leroux JC. The journey of a drug-carrier in the body: an anatomo-physiological perspective. Journal of Controlled Release : Official Journal of the Controlled Release Society. 161: 152-63. PMID 22001607 DOI: 10.1016/J.Jconrel.2011.09.098 |
0.631 |
|
2012 |
Felber AE, Dufresne MH, Leroux JC. pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates. Advanced Drug Delivery Reviews. 64: 979-92. PMID 21996056 DOI: 10.1016/J.Addr.2011.09.006 |
0.438 |
|
2011 |
Gao H, Elsabahy M, Giger EV, Ma J, Prud'homme RE, Leroux JC. Self assembling properties of aminated poly(glycerol methacrylate)s. Journal of Controlled Release : Official Journal of the Controlled Release Society. 152: e142-3. PMID 22195809 DOI: 10.1016/J.Jconrel.2011.08.050 |
0.36 |
|
2011 |
Bayó-Puxan N, Dufresne MH, Felber AE, Castagner B, Leroux JC. Preparation of polyion complex micelles from poly(ethylene glycol)-block-polyions. Journal of Controlled Release : Official Journal of the Controlled Release Society. 156: 118-27. PMID 21820022 DOI: 10.1016/J.Jconrel.2011.07.027 |
0.392 |
|
2011 |
Bertrand N, Gauthier MA, Bouvet C, Moreau P, Petitjean A, Leroux JC, Leblond J. New pharmaceutical applications for macromolecular binders. Journal of Controlled Release : Official Journal of the Controlled Release Society. 155: 200-10. PMID 21571017 DOI: 10.1016/J.Jconrel.2011.04.027 |
0.617 |
|
2011 |
Luciani P, Fevre M, Leroux JC. Development and physico-chemical characterization of a liposomal formulation of istaroxime. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 79: 285-93. PMID 21550400 DOI: 10.1016/J.Ejpb.2011.04.013 |
0.391 |
|
2011 |
Felber AE, Castagner B, Elsabahy M, Deleavey GF, Damha MJ, Leroux JC. siRNA nanocarriers based on methacrylic acid copolymers. Journal of Controlled Release : Official Journal of the Controlled Release Society. 152: 159-67. PMID 21195736 DOI: 10.1016/J.Jconrel.2010.12.012 |
0.362 |
|
2011 |
Giger EV, Puigmartí-Luis J, Schlatter R, Castagner B, Dittrich PS, Leroux JC. Gene delivery with bisphosphonate-stabilized calcium phosphate nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 150: 87-93. PMID 21111013 DOI: 10.1016/J.Jconrel.2010.11.012 |
0.346 |
|
2011 |
Kenth S, Sylvestre JP, Fuhrmann K, Meunier M, Leroux JC. Fabrication of paclitaxel nanocrystals by femtosecond laser ablation and fragmentation. Journal of Pharmaceutical Sciences. 100: 1022-30. PMID 20809524 DOI: 10.1002/Jps.22335 |
0.319 |
|
2011 |
Pinier M, Fuhrmann G, Verdu E, Leroux J. Corrigendum: Prevention Measures and Exploratory Pharmacological Treatments of Celiac Disease American Journal of Gastroenterology. 106: 375. DOI: 10.1038/Ajg.2010.454 |
0.739 |
|
2010 |
Fuhrmann K, Gauthier MA, Leroux JC. Crosslinkable polymers for nanocrystal stabilization. Journal of Controlled Release : Official Journal of the Controlled Release Society. 148: e12-3. PMID 21529591 DOI: 10.1016/J.Jconrel.2010.07.006 |
0.317 |
|
2010 |
Bertrand N, Bouvet C, Moreau P, Leroux JC. Transmembrane pH-gradient liposomes to treat cardiovascular drug intoxication. Acs Nano. 4: 7552-8. PMID 21067150 DOI: 10.1021/Nn101924A |
0.665 |
|
2010 |
Pinier M, Fuhrmann G, Verdu EF, Verdu E, Leroux JC. Prevention measures and exploratory pharmacological treatments of celiac disease. The American Journal of Gastroenterology. 105: 2551-61; quiz 2562. PMID 20877349 DOI: 10.1038/Ajg.2010.372 |
0.746 |
|
2010 |
Gaucher G, Satturwar P, Jones MC, Furtos A, Leroux JC. Polymeric micelles for oral drug delivery. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 76: 147-58. PMID 20600891 DOI: 10.1016/J.Ejpb.2010.06.007 |
0.378 |
|
2010 |
Leblond J, Gao H, Petitjean A, Leroux JC. pH-Responsive molecular tweezers. Journal of the American Chemical Society. 132: 8544-5. PMID 20524610 DOI: 10.1021/Ja103153T |
0.33 |
|
2010 |
Simard P, Leroux JC. In vivo evaluation of pH-sensitive polymer-based immunoliposomes targeting the CD33 antigen. Molecular Pharmaceutics. 7: 1098-107. PMID 20476756 DOI: 10.1021/Mp900261M |
0.346 |
|
2010 |
Bastiat G, Plourde F, Motulsky A, Furtos A, Dumont Y, Quirion R, Fuhrmann G, Leroux JC. Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease. Biomaterials. 31: 6031-8. PMID 20472283 DOI: 10.1016/J.Biomaterials.2010.04.009 |
0.309 |
|
2010 |
Gao H, Elsabahy M, Giger EV, Li D, Prud'homme RE, Leroux JC. Aminated linear and star-shape poly(glycerol methacrylate)s: synthesis and self-assembling properties. Biomacromolecules. 11: 889-95. PMID 20201490 DOI: 10.1021/Bm901241K |
0.377 |
|
2010 |
Bertrand N, Simard P, Leroux JC. Serum-stable, long-circulating, pH-sensitive PEGylated liposomes. Methods in Molecular Biology (Clifton, N.J.). 605: 545-58. PMID 20072905 DOI: 10.1007/978-1-60327-360-2_36 |
0.695 |
|
2010 |
Gaucher G, Marchessault RH, Leroux JC. Polyester-based micelles and nanoparticles for the parenteral delivery of taxanes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 143: 2-12. PMID 19925835 DOI: 10.1016/J.Jconrel.2009.11.012 |
0.404 |
|
2010 |
Liang L, Pinier M, Leroux JC, Subirade M. Interaction of alpha-gliadin with polyanions: design considerations for sequestrants used in supportive treatment of celiac disease. Biopolymers. 93: 418-28. PMID 19921745 DOI: 10.1002/Bip.21352 |
0.785 |
|
2010 |
Jones MC, Leroux JC. Reverse micelles from amphiphilic branched polymers Soft Matter. 6: 5850-5859. DOI: 10.1039/C0Sm00272K |
0.358 |
|
2010 |
Pinier M, Fuhrmann G, Verdu E, Leroux J. What's Hot in the Red Journal The American Journal of Gastroenterology. 105: 2517-2519. DOI: 10.1038/Ajg.2010.446 |
0.731 |
|
2009 |
Bastiat G, Leroux JC. Pharmaceutical organogels prepared from aromatic amino acid derivatives. Journal of Materials Chemistry. 19: 3867-3877. PMID 27099412 DOI: 10.1039/B822657A |
0.321 |
|
2009 |
Huynh L, Leroux JC, Allen C. Enhancement of docetaxel solubility via conjugation of formulation-compatible moieties. Organic & Biomolecular Chemistry. 7: 3437-46. PMID 19675898 DOI: 10.1039/B906862G |
0.352 |
|
2009 |
Simard P, Leroux JC. pH-sensitive immunoliposomes specific to the CD33 cell surface antigen of leukemic cells. International Journal of Pharmaceutics. 381: 86-96. PMID 19446624 DOI: 10.1016/J.Ijpharm.2009.05.013 |
0.399 |
|
2009 |
Bertrand N, Fleischer JG, Wasan KM, Leroux JC. Pharmacokinetics and biodistribution of N-isopropylacrylamide copolymers for the design of pH-sensitive liposomes. Biomaterials. 30: 2598-605. PMID 19176241 DOI: 10.1016/J.Biomaterials.2008.12.082 |
0.672 |
|
2009 |
Gaucher G, Asahina K, Wang J, Leroux JC. Effect of poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as coating agent on the opsonization, phagocytosis, and pharmacokinetics of biodegradable nanoparticles. Biomacromolecules. 10: 408-16. PMID 19133718 DOI: 10.1021/Bm801178F |
0.306 |
|
2009 |
Pinier M, Verdu EF, Nasser-Eddine M, David CS, Vézina A, Rivard N, Leroux JC. Polymeric binders suppress gliadin-induced toxicity in the intestinal epithelium. Gastroenterology. 136: 288-98. PMID 18992747 DOI: 10.1053/J.Gastro.2008.09.016 |
0.76 |
|
2009 |
Liang L, Pinier M, Leroux JC, Subirade M. Interaction of alpha-gliadin with poly(HEMA-co-SS): structural characterization and biological implication. Biopolymers. 91: 169-78. PMID 18975377 DOI: 10.1002/Bip.21109 |
0.775 |
|
2009 |
Elsabahy M, Wazen N, Bayó-Puxan N, Deleavey G, Servant M, Damha MJ, Leroux J. Delivery of Nucleic Acids through the Controlled Disassembly of Multifunctional Nanocomplexes Advanced Functional Materials. 19: 3862-3867. DOI: 10.1002/Adfm.200901139 |
0.388 |
|
2008 |
Elsabahy M, Zhang M, Gan SM, Waldron KC, Leroux JC. Synthesis and enzymatic stability of PEGylated oligonucleotide duplexes and their self-assemblies with polyamidoamine dendrimers. Soft Matter. 4: 294-302. PMID 32907243 DOI: 10.1039/B714221H |
0.361 |
|
2008 |
Jones MC, Gao H, Leroux JC. Reverse polymeric micelles for pharmaceutical applications. Journal of Controlled Release : Official Journal of the Controlled Release Society. 132: 208-15. PMID 18571266 DOI: 10.1016/J.Jconrel.2008.05.006 |
0.309 |
|
2008 |
Dufresne MH, Elsabahy M, Leroux JC. Characterization of polyion complex micelles designed to address the challenges of oligonucleotide delivery. Pharmaceutical Research. 25: 2083-93. PMID 18452054 DOI: 10.1007/S11095-008-9591-6 |
0.334 |
|
2008 |
Vintiloiu A, Leroux JC. Organogels and their use in drug delivery--a review. Journal of Controlled Release : Official Journal of the Controlled Release Society. 125: 179-92. PMID 18082283 DOI: 10.1016/J.Jconrel.2007.09.014 |
0.31 |
|
2008 |
Gao H, Jones M, Chen J, Liang Y, Prud’homme RE, Leroux J. Hydrophilic Nanoreservoirs Embedded into Polymeric Micro/Nanoparticles: An Approach To Compatibilize Polar Molecules with Hydrophobic Matrixes Chemistry of Materials. 20: 4191-4193. DOI: 10.1021/Cm8012792 |
0.304 |
|
2008 |
Gao H, Jones M, Chen J, Prud’homme RE, Leroux J. Core Cross-Linked Reverse Micelles from Star-Shaped Polymers Chemistry of Materials. 20: 3063-3067. DOI: 10.1021/Cm703370R |
0.32 |
|
2007 |
Leroux JC. Injectable nanocarriers for biodetoxification. Nature Nanotechnology. 2: 679-84. PMID 18654405 DOI: 10.1038/Nnano.2007.339 |
0.313 |
|
2007 |
Elsabahy M, Perron ME, Bertrand N, Yu GE, Leroux JC. Solubilization of docetaxel in poly(ethylene oxide)-block-poly(butylene/styrene oxide) micelles. Biomacromolecules. 8: 2250-7. PMID 17579476 DOI: 10.1021/Bm070226V |
0.656 |
|
2007 |
Rossi J, Giasson S, Khalid MN, Delmas P, Allen C, Leroux JC. Long-circulating poly(ethylene glycol)-coated emulsions to target solid tumors. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 67: 329-38. PMID 17490868 DOI: 10.1016/J.Ejpb.2007.03.016 |
0.348 |
|
2007 |
Yessine MA, Dufresne MH, Meier C, Petereit HU, Leroux JC. Proton-actuated membrane-destabilizing polyion complex micelles. Bioconjugate Chemistry. 18: 1010-4. PMID 17402703 DOI: 10.1021/Bc060159M |
0.381 |
|
2007 |
Gaucher G, Poreba M, Ravenelle F, Leroux JC. Poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as polymeric emulsifier for the preparation of biodegradable nanoparticles. Journal of Pharmaceutical Sciences. 96: 1763-75. PMID 17387697 DOI: 10.1002/Jps.20833 |
0.34 |
|
2007 |
Burt H, Leroux JC, Amsden B, Uludag H. Drug delivery: a Canadian perspective. 25 years of innovative drug delivery research. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 65: iii. PMID 17280822 DOI: 10.1016/J.Ejpb.2007.01.003 |
0.317 |
|
2007 |
Dhanikula AB, Khalid NM, Lee SD, Yeung R, Risovic V, Wasan KM, Leroux JC. Long circulating lipid nanocapsules for drug detoxification. Biomaterials. 28: 1248-57. PMID 17125832 DOI: 10.1016/J.Biomaterials.2006.10.036 |
0.371 |
|
2007 |
Satturwar P, Eddine MN, Ravenelle F, Leroux JC. pH-responsive polymeric micelles of poly(ethylene glycol)-b-poly(alkyl(meth)acrylate-co-methacrylic acid): influence of the copolymer composition on self-assembling properties and release of candesartan cilexetil. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 65: 379-87. PMID 17123802 DOI: 10.1016/J.Ejpb.2006.09.012 |
0.439 |
|
2007 |
Kalarickal NC, Rimmer S, Sarker P, Leroux JC. Thiol-functionalized poly(ethylene glycol)-b-polyesters: Synthesis and characterization Macromolecules. 40: 1874-1880. DOI: 10.1021/Ma062377G |
0.356 |
|
2007 |
Gao H, Jones MC, Tewari P, Ranger M, Leroux JC. Star-shaped alkylated poly(glycerol methacrylate) reverse micelles: Synthesis and evaluation of their solubilizing properties in dichloromethane Journal of Polymer Science, Part a: Polymer Chemistry. 45: 2425-2435. DOI: 10.1002/Pola.22004 |
0.363 |
|
2006 |
Jones MC, Tewari P, Blei C, Hales K, Pochan DJ, Leroux JC. Self-assembled nanocages for hydrophilic guest molecules. Journal of the American Chemical Society. 128: 14599-605. PMID 17090044 DOI: 10.1021/Ja065462C |
0.348 |
|
2006 |
Dhanikula AB, Lafleur M, Leroux JC. Characterization and in vitro evaluation of spherulites as sequestering vesicles with potential application in drug detoxification. Biochimica Et Biophysica Acta. 1758: 1787-96. PMID 16999932 DOI: 10.1016/J.Bbamem.2006.08.005 |
0.411 |
|
2006 |
Khalid MN, Simard P, Hoarau D, Dragomir A, Leroux JC. Long circulating poly(ethylene glycol)-decorated lipid nanocapsules deliver docetaxel to solid tumors Pharmaceutical Research. 23: 752-758. PMID 16550475 DOI: 10.1007/S11095-006-9662-5 |
0.362 |
|
2006 |
Yessine M, Meier C, Petereit H, Leroux J. On the role of methacrylic acid copolymers in the intracellular delivery of antisense oligonucleotides. European Journal of Pharmaceutics and Biopharmaceutics. 63: 1-10. PMID 16364618 DOI: 10.1016/J.Ejpb.2005.10.010 |
0.417 |
|
2005 |
Gaucher G, Dufresne MH, Sant VP, Kang N, Maysinger D, Leroux JC. Block copolymer micelles: preparation, characterization and application in drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 109: 169-88. PMID 16289422 DOI: 10.1016/J.Jconrel.2005.09.034 |
0.406 |
|
2005 |
Plourde F, Motulsky A, Couffin-Hoarau AC, Hoarau D, Ong H, Leroux JC. First report on the efficacy of l-alanine-based in situ-forming implants for the long-term parenteral delivery of drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 108: 433-41. PMID 16182402 DOI: 10.1016/J.Jconrel.2005.08.016 |
0.356 |
|
2005 |
Simard P, Hoarau D, Khalid MN, Roux E, Leroux JC. Preparation and in vivo evaluation of PEGylated spherulite formulations. Biochimica Et Biophysica Acta. 1715: 37-48. PMID 16084487 DOI: 10.1016/J.Bbamem.2005.06.013 |
0.77 |
|
2005 |
Dufresne M, Gauthier MA, Leroux J. Thiol-functionalized polymeric micelles: from molecular recognition to improved mucoadhesion. Bioconjugate Chemistry. 16: 1027-1033. PMID 16029046 DOI: 10.1021/Bc050007B |
0.368 |
|
2005 |
Motulsky A, Lafleur M, Couffin-Hoarau AC, Hoarau D, Boury F, Benoit JP, Leroux JC. Characterization and biocompatibility of organogels based on L-alanine for parenteral drug delivery implants. Biomaterials. 26: 6242-53. PMID 15916802 DOI: 10.1016/J.Biomaterials.2005.04.004 |
0.349 |
|
2005 |
Sant VP, Smith D, Leroux J. Enhancement of oral bioavailability of poorly water-soluble drugs by poly(ethylene glycol)-block-poly(alkyl acrylate -co -methacrylic acid) self-assemblies Journal of Controlled Release. 104: 289-300. PMID 15907580 DOI: 10.1016/J.Jconrel.2005.02.010 |
0.433 |
|
2005 |
Kang N, Perron ME, Prud'homme RE, Zhang Y, Gaucher G, Leroux JC. Stereocomplex block copolymer micelles: core-shell nanostructures with enhanced stability. Nano Letters. 5: 315-9. PMID 15794618 DOI: 10.1021/Nl048037V |
0.359 |
|
2005 |
Ruel-Gariépy E, Shive M, Bichara A, Berrada M, Le Garrec D, Chenite A, Leroux JC. A thermosensitive chitosan-based hydrogel for the local delivery of paclitaxel. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 57: 53-63. PMID 14729080 DOI: 10.1016/S0939-6411(03)00095-X |
0.32 |
|
2004 |
Pétriat F, Roux E, Leroux JC, Giasson S. Study of molecular interactions between a phospholipidic layer and a pH-sensitive polymer using the Langmuir balance technique. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 1393-400. PMID 15803724 DOI: 10.1021/La035583F |
0.771 |
|
2004 |
Hoarau D, Delmas P, David S, Roux E, Leroux JC. Novel long-circulating lipid nanocapsules. Pharmaceutical Research. 21: 1783-9. PMID 15553223 DOI: 10.1023/B:Pham.0000045229.87844.21 |
0.746 |
|
2004 |
Couffin-Hoarau A, Leroux J. Report on the use of poly(organophosphazenes) for the design of stimuli-responsive vesicles. Biomacromolecules. 5: 2082-2087. PMID 15530020 DOI: 10.1021/Bm0400527 |
0.414 |
|
2004 |
Ruel-Gariépy E, Leroux J. In situ-forming hydrogels--review of temperature-sensitive systems. European Journal of Pharmaceutics and Biopharmaceutics. 58: 409-426. PMID 15296964 DOI: 10.1016/J.Ejpb.2004.03.019 |
0.362 |
|
2004 |
Fournier E, Dufresne MH, Smith DC, Ranger M, Leroux JC. A novel one-step drug-loading procedure for water-soluble amphiphilic nanocarriers. Pharmaceutical Research. 21: 962-8. PMID 15212160 DOI: 10.1023/B:Pham.0000029284.40637.69 |
0.352 |
|
2004 |
Sant VP, Smith D, Leroux J. Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: preparation and characterization. Journal of Controlled Release. 97: 301-312. PMID 15196757 DOI: 10.1016/J.Jconrel.2004.03.026 |
0.448 |
|
2004 |
Yessine M, Leroux J. Membrane-destabilizing polyanions: interaction with lipid bilayers and endosomal escape of biomacromolecules. Advanced Drug Delivery Reviews. 56: 999-1021. PMID 15066757 DOI: 10.1016/J.Addr.2003.10.039 |
0.433 |
|
2004 |
Dufresne M, Leroux J. Study of the micellization behavior of different order amino block copolymers with heparin. Pharmaceutical Research. 21: 160-169. PMID 14984271 DOI: 10.1023/B:Pham.0000012164.60867.C6 |
0.409 |
|
2004 |
Roux E, Passirani C, Scheffold S, Benoit JP, Leroux JC. Serum-stable and long-circulating, PEGylated, pH-sensitive liposomes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 94: 447-51. PMID 14976960 DOI: 10.1016/J.Jconrel.2003.10.024 |
0.77 |
|
2004 |
Le Garrec D, Ranger M, Leroux JC. Micelles in anticancer drug delivery American Journal of Drug Delivery. 2: 15-42. DOI: 10.2165/00137696-200402010-00002 |
0.393 |
|
2004 |
Luo L, Ranger M, Lessard DG, Garrec DL, Gori S, Leroux JC, Rimmer S, Smith D. Novel amphiphilic diblock copolymer of low molecular weight poly(N-vinylpyrrolidone)-block-poly(D,L-lactide): Synthesis, characterization, and micellization Macromolecules. 37: 4008-4013. DOI: 10.1021/Ma035910Q |
0.317 |
|
2004 |
Kang N, Leroux JC. Triblock and star-block copolymers of N-(2-hydroxypropyl)methacrylamide or N-vinyl-2-pyrrolidone and d,l-lactide: Synthesis and self-assembling properties in water Polymer. 45: 8967-8980. DOI: 10.1016/J.Polymer.2004.10.081 |
0.327 |
|
2004 |
Leroux JC. pH-responsive carriers for enhancing the cytoplasmic delivery of macromolecular drugs Advanced Drug Delivery Reviews. 56: 925-926. DOI: 10.1016/J.Addr.2003.11.004 |
0.381 |
|
2003 |
Rahmouni M, Lenaerts V, Massuelle D, Doelker E, Johnson M, Leroux JC. Characterization of binary mixtures consisting of cross-linked high amylose starch and hydroxypropylmethylcellulose used in the preparation of controlled release tablets. Pharmaceutical Development and Technology. 8: 335-48. PMID 14601958 DOI: 10.1081/Pdt-120024687 |
0.779 |
|
2003 |
Jones MC, Ranger M, Leroux JC. pH-sensitive unimolecular polymeric micelles: synthesis of a novel drug carrier. Bioconjugate Chemistry. 14: 774-81. PMID 12862430 DOI: 10.1021/Bc020041F |
0.396 |
|
2003 |
Yessine MA, Lafleur M, Meier C, Petereit HU, Leroux JC. Characterization of the membrane-destabilizing properties of different pH-sensitive methacrylic acid copolymers. Biochimica Et Biophysica Acta. 1613: 28-38. PMID 12832084 DOI: 10.1016/S0005-2736(03)00137-8 |
0.389 |
|
2003 |
Roux E, Lafleur M, Lataste E, Moreau P, Leroux JC. On the characterization of pH-sensitive liposome/polymer complexes. Biomacromolecules. 4: 240-8. PMID 12625718 DOI: 10.1021/Bm025651X |
0.782 |
|
2002 |
Rahmouni M, Lenaerts V, Massuelle D, Doelker E, Leroux JC. Influence of physical parameters and lubricants on the compaction properties of granulated and non-granulated cross-linked high amylose starch. Chemical & Pharmaceutical Bulletin. 50: 1155-62. PMID 12237529 DOI: 10.1248/Cpb.50.1155 |
0.754 |
|
2002 |
Roux E, Francis M, Winnik FM, Leroux JC. Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs. International Journal of Pharmaceutics. 242: 25-36. PMID 12176222 DOI: 10.1016/S0378-5173(02)00183-7 |
0.792 |
|
2002 |
Roux E, Stomp R, Giasson S, Pézolet M, Moreau P, Leroux JC. Steric stabilization of liposomes by pH-responsive N-isopropylacrylamide copolymer. Journal of Pharmaceutical Sciences. 91: 1795-802. PMID 12115806 DOI: 10.1002/Jps.10172 |
0.787 |
|
2002 |
Molinaro G, Leroux J, Damas J, Adam A. Biocompatibility of thermosensitive chitosan-based hydrogels: an in vivo experimental approach to injectable biomaterials Biomaterials. 23: 2717-2722. PMID 12059021 DOI: 10.1016/S0142-9612(02)00004-2 |
0.317 |
|
2002 |
Dube D, Francis M, Leroux J, Winnik FM. Preparation and tumor cell uptake of poly(N-isopropylacrylamide) folate conjugates. Bioconjugate Chemistry. 13: 685-692. PMID 12009963 DOI: 10.1021/Bc010084G |
0.346 |
|
2001 |
Francis MF, Dhara G, Winnik FM, Leroux J. In vitro evaluation of pH-sensitive polymer/niosome complexes. Biomacromolecules. 2: 741-749. PMID 11710027 DOI: 10.1021/Bm010036Z |
0.415 |
|
2001 |
Benahmed A, Ranger M, Leroux JC. Novel polymeric micelles based on the amphiphilic diblock copolymer poly(N-vinyl-2-pyrrolidone)-block-poly(D,L-lactide). Pharmaceutical Research. 18: 323-8. PMID 11442272 DOI: 10.1023/A:1011054930439 |
0.319 |
|
2001 |
Leroux J, Roux E, Le Garrec D, Hong K, Drummond DC. N-isopropylacrylamide copolymers for the preparation of pH-sensitive liposomes and polymeric micelles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 72: 71-84. PMID 11389986 DOI: 10.1016/S0168-3659(01)00263-2 |
0.796 |
|
2001 |
Rahmouni M, Chouinard F, Nekka F, Lenaerts V, Leroux JC. Enzymatic degradation of cross-linked high amylose starch tablets and its effect on in vitro release of sodium diclofenac. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 51: 191-8. PMID 11343882 DOI: 10.1016/S0939-6411(01)00127-8 |
0.785 |
|
2001 |
Jarry C, Chaput C, Chenite A, Renaud MA, Buschmann M, Leroux JC. Effects of steam sterilization on thermogelling chitosan-based gels. Journal of Biomedical Materials Research. 58: 127-35. PMID 11153009 DOI: 10.1002/1097-4636(2001)58:1<127::Aid-Jbm190>3.0.Co;2-G |
0.322 |
|
2001 |
Ranger M, Jones MC, Yessine MA, Leroux JC. From well-defined diblock copolymers prepared by a versatile atom transfer radical polymerization method to supramolecular assemblies Journal of Polymer Science, Part a: Polymer Chemistry. 39: 3861-3874. DOI: 10.1002/Pola.10029 |
0.409 |
|
2000 |
Drummond DC, Zignani M, Leroux J. Current status of pH-sensitive liposomes in drug delivery. Progress in Lipid Research. 39: 409-460. PMID 11082506 DOI: 10.1016/S0163-7827(00)00011-4 |
0.382 |
|
2000 |
Zignani M, Drummond DC, Meyer O, Hong K, Leroux J. In vitro characterization of a novel polymeric-based pH-sensitive liposome system. Biochimica Et Biophysica Acta. 1463: 383-394. PMID 10675515 DOI: 10.1016/S0005-2736(99)00234-5 |
0.452 |
|
1999 |
Jones M, Leroux J. Polymeric micelles - a new generation of colloidal drug carriers. European Journal of Pharmaceutics and Biopharmaceutics. 48: 101-111. PMID 10469928 DOI: 10.1016/S0939-6411(99)00039-9 |
0.398 |
|
1998 |
Meyer O, Papahadjopoulos D, Leroux J. Copolymers of N‐isopropylacrylamide can trigger pH sensitivity to stable liposomes Febs Letters. 421: 61-64. PMID 9462840 DOI: 10.1016/S0014-5793(97)01520-2 |
0.44 |
|
1996 |
Leroux JC, Cozens R, Roesel JL, Galli B, Kubel F, Doelker E, Gurny R. Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice. Journal of Pharmaceutical Sciences. 84: 1387-91. PMID 8748318 DOI: 10.1002/Jps.2600841202 |
0.311 |
|
1994 |
Allémann E, Leroux JC, Gurny R, Doelker E. In vitro extended-release properties of drug-loaded poly(DL-lactic acid) nanoparticles produced by a salting-out procedure. Pharmaceutical Research. 10: 1732-7. PMID 7905625 DOI: 10.1023/A:1018970030327 |
0.377 |
|
1991 |
Labib A, Lenaerts V, Chouinard F, Leroux JC, Ouellet R, van Lier JE. Biodegradable nanospheres containing phthalocyanines and naphthalocyanines for targeted photodynamic tumor therapy. Pharmaceutical Research. 8: 1027-31. PMID 1924155 DOI: 10.1023/A:1015809124895 |
0.386 |
|
1991 |
Chouinard F, Kan FWK, Leroux J, Foucher C, Lenaerts V. Preparation and purification of polyisohexylcyanoacrylate nanocapsules International Journal of Pharmaceutics. 72: 211-217. DOI: 10.1016/0378-5173(91)90110-A |
0.332 |
|
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