Robert L. Martuza - Publications

Affiliations: 
Massachusetts General Hospital, Boston, MA 

181 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shimizu K, Kahramanian A, Jabbar MADA, Turna Demir F, Gokyer D, Uthamacumaran A, Rajan A, Saad MA, Gorham J, Wakimoto H, Martuza RL, Rabkin SD, Hasan T, Wakimoto H. Photodynamic augmentation of oncolytic virus therapy for central nervous system malignancies. Cancer Letters. 572: 216363. PMID 37619813 DOI: 10.1016/j.canlet.2023.216363  0.326
2021 Jahan N, Ghouse SM, Martuza RL, Rabkin SD. In Situ Cancer Vaccination and Immunovirotherapy Using Oncolytic HSV. Viruses. 13. PMID 34578321 DOI: 10.3390/v13091740  0.349
2020 Li M, Li G, Kiyokawa J, Tirmizi Z, Richardson LG, Ning J, Das S, Martuza RL, Stemmer-Rachamimov A, Rabkin SD, Wakimoto H. Characterization and oncolytic virus targeting of FAP-expressing tumor-associated pericytes in glioblastoma. Acta Neuropathologica Communications. 8: 221. PMID 33308315 DOI: 10.1186/s40478-020-01096-0  0.378
2020 Saha D, Rabkin SD, Martuza RL. Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma. Journal For Immunotherapy of Cancer. 8. PMID 32457126 DOI: 10.1136/jitc-2019-000345  0.366
2019 Ning JF, Stanciu M, Humphrey MR, Gorham J, Wakimoto H, Nishihara R, Lees J, Zou L, Martuza RL, Wakimoto H, Rabkin SD. Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma. Nature Communications. 10: 2910. PMID 31266951 DOI: 10.1038/S41467-019-10993-5  0.421
2019 Wang L, Ning J, Wakimoto H, Wu S, Wu CL, Humphrey MR, Rabkin SD, Martuza RL. Oncolytic Herpes Simplex Virus and PI3K Inhibitor BKM120 Synergize to Promote Killing of Prostate Cancer Stem-like Cells. Molecular Therapy Oncolytics. 13: 58-66. PMID 31016228 DOI: 10.1016/j.omto.2019.03.008  0.457
2019 Chongsathidkiet P, Jackson C, Koyama S, Loebel F, Cui X, Farber SH, Woroniecka K, Elsamadicy AA, Dechant CA, Kemeny HR, Sanchez-Perez L, Cheema TA, Souders NC, Herndon JE, Coumans JV, ... ... Martuza RL, et al. Author Correction: Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors. Nature Medicine. PMID 30670876 DOI: 10.1038/s41591-019-0355-0  0.305
2019 Tanaka S, Luk S, Kiyokawa J, Onozato ML, Iafrate AJ, Shah K, Martuza RL, Rabkin SD, Batchelor TT, Cahill DP, Chi AS, Wakimoto H. Genetically distinct glioma stem-like cell xenografts established from paired glioblastoma samples harvested before and after molecularly targeted therapy. Scientific Reports. 9: 139. PMID 30644426 DOI: 10.1038/S41598-018-37437-2  0.301
2018 Chongsathidkiet P, Jackson C, Koyama S, Loebel F, Cui X, Farber SH, Woroniecka K, Elsamadicy AA, Dechant CA, Kemeny HR, Sanchez-Perez L, Cheema TA, Souders NC, Herndon JE, Coumans JV, ... ... Martuza RL, et al. Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors. Nature Medicine. PMID 30104766 DOI: 10.1038/s41591-018-0135-2  0.36
2018 Saha D, Martuza RL, Rabkin SD. Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma. Immunotherapy. 10: 779-786. PMID 30008259 DOI: 10.2217/imt-2018-0009  0.407
2018 Peters C, Paget M, Tshilenge KT, Saha D, Antoszczyk S, Baars A, Frost T, Martuza RL, Wakimoto H, Rabkin SD. RESTRICTION OF γ34.5-DELETED ONCOLYTIC HERPES SIMPLEX VIRUS REPLICATION IN GLIOBLASTOMA STEM-LIKE CELLS. Journal of Virology. PMID 29793956 DOI: 10.1128/JVI.00246-18  0.459
2018 Saha D, Wakimoto H, Peters CW, Antoszczyk SJ, Rabkin SD, Martuza RL. Combinatorial effects of VEGFR kinase inhibitor axitinib and oncolytic virotherapy in mouse and human glioblastoma stem-like cell models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29599413 DOI: 10.1158/1078-0432.CCR-17-1717  0.394
2018 Hua L, Gartner A, Kiyokawa J, Rabkin S, Martuza R, Wakimoto H. EXTH-20. HISTONE DEACETYLASE INHIBITOR ENHANCES ONCOLYTIC HERPES SIMPLEX VIRUS THERAPY FOR MALIGNANT MENINGIOMA Neuro-Oncology. 20: vi89-vi89. DOI: 10.1093/Neuonc/Noy148.369  0.317
2017 Saha D, Martuza RL, Rabkin SD. Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade. Cancer Cell. 32: 253-267.e5. PMID 28810147 DOI: 10.1016/j.ccell.2017.07.006  0.348
2017 Esaki S, Nigim F, Moon E, Luk S, Kiyokawa J, Curry W, Cahill DP, Chi AS, Iafrate AJ, Martuza RL, Rabkin SD, Wakimoto H. Blockade of transforming growth factor-β signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models. International Journal of Cancer. PMID 28801914 DOI: 10.1002/ijc.30929  0.427
2017 Kim D, Niemierko A, Hwang WL, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Oh KS, Loeffler JS, Shih HA. Histopathological prognostic factors of recurrence following definitive therapy for atypical and malignant meningiomas. Journal of Neurosurgery. 1-10. PMID 28621619 DOI: 10.3171/2016.11.Jns16913  0.345
2017 Ning J, Wakimoto H, Peters C, Martuza RL, Rabkin SD. Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma. Journal of the National Cancer Institute. 109: 1-13. PMID 28376211 DOI: 10.1093/jnci/djw229  0.329
2017 Ning J, Wakimoto H, Martuza RL, Rabkin SD. Abstract 1122: ATR inhibitors synergize with PARP inhibitors in killing glioblastoma stem cells and treating glioblastoma Cancer Research. 77: 1122-1122. DOI: 10.1158/1538-7445.Am2017-1122  0.444
2016 Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, ... ... Martuza RL, et al. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma. Nature. PMID 27806376 DOI: 10.1038/Nature20123  0.312
2016 Venteicher AS, Tirosh I, Hebert C, Escalante L, Martuza RL, Nahed BV, Curry WT, Cahill DP, Bernstein B, Louis DN, Regev A, Suva M. 142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis. Neurosurgery. 63: 158. PMID 27399421 DOI: 10.1227/01.Neu.0000489712.44702.0D  0.385
2016 Nigim F, Esaki SI, Hood M, Lelic N, James MF, Ramesh V, Stemmer-Rachamimov A, Cahill DP, Brastianos PK, Rabkin SD, Martuza RL, Wakimoto H. A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus. Neuro-Oncology. PMID 26951380 DOI: 10.1093/Neuonc/Now031  0.353
2016 Saha D, Martuza R, Rabkin S. Abstract B116: Immunovirotherapy in combination with immune checkpoint inhibitors for treating glioblastoma Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B116  0.446
2016 Grosskopf A, Rabkin SD, Martuza RL, Wakimoto H. 107. Tracking Target Cell Fate After Oncolytic Herpes Simplex Virus Infection Molecular Therapy. 24: S46. DOI: 10.1016/S1525-0016(16)32916-1  0.404
2015 Nigim F, Cavanaugh J, Patel AP, Curry WT, Esaki S, Kasper EM, Chi AS, Louis DN, Martuza RL, Rabkin SD, Wakimoto H. Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment. Journal of Neuropathology and Experimental Neurology. 74: 710-22. PMID 26083570 DOI: 10.1097/Nen.0000000000000210  0.378
2015 Lu L, Saha D, Martuza RL, Rabkin SD, Wakimoto H. Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma. Journal of Neuro-Oncology. 121: 91-100. PMID 25213669 DOI: 10.1007/s11060-014-1612-1  0.403
2015 Ning J, Wakimoto H, Martuza R, Rabkin S. Abstract 4227: PARP inhibitors sensitize glioblastoma stem cells to oncolytic herpes simplex virus therapy Cancer Research. 75: 4227-4227. DOI: 10.1158/1538-7445.Am2015-4227  0.392
2015 Venteicher A, Tirosh I, Hebert C, Escalante L, Nahed B, Cahill D, Curry W, Martuza R, Bernstein B, Louis D, Regev A, Suva M. STEM-22LARGE-SCALE SINGLE-CELL RNA-seq REVEALS A DEVELOPMENTAL CELLULAR HIERARCHY IN HUMAN OLIGODENDROGLIOMA Neuro-Oncology. 17: v212.4-v213. DOI: 10.1093/Neuonc/Nov234.22  0.448
2015 Nigim F, Rabkin SD, Brastianos P, Ramesh V, Cahill D, Santagata S, Martuza RL, Wakimoto H. MNGO-16ESTABLISHMENT OF A PATIENT - DERIVED ORTHOTOPIC MALIGNANT MENINGIOMA MODEL FOR THE DEVELOPMENT OF TARGETED THERAPY Neuro-Oncology. 17: v133.2-v133. DOI: 10.1093/Neuonc/Nov220.15  0.478
2015 Saha D, Martuza RL, Rabkin SD. 624. Immunovirotherapy Combined with Immune Checkpoint Inhibitors for Treating Glioblastoma Molecular Therapy. 23: S248. DOI: 10.1016/S1525-0016(16)34233-2  0.415
2014 Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science (New York, N.Y.). 344: 1396-401. PMID 24925914 DOI: 10.1126/Science.1254257  0.367
2014 Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell. 157: 580-94. PMID 24726434 DOI: 10.1016/J.Cell.2014.02.030  0.396
2014 Antoszczyk S, Spyra M, Mautner VF, Kurtz A, Stemmer-Rachamimov AO, Martuza RL, Rabkin SD. Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus. Neuro-Oncology. 16: 1057-66. PMID 24470552 DOI: 10.1093/Neuonc/Not317  0.441
2014 Sheth SA, Tirino JL, Martuza RL. Vestibular schwannoma: suboccipital approach. Neurosurgical Focus. 36: 1. PMID 24380512 DOI: 10.3171/2014.V1.Focus13318  0.328
2014 Esaki S, Rabkin SD, Martuza RL, Wakimoto H. ET-17 * TRANSIENT FASTING ENHANCES REPLICATION AND THERAPEUTIC ACTIVITY OF ONCOLYTIC HSV IN GLIOBLASTOMA THERAPY Neuro-Oncology. 16: v82-v83. DOI: 10.1093/neuonc/nou255.17  0.44
2014 Nigim F, Cavanaugh J, Patel AP, Curry WT, Kasper EM, Chi AS, Martuza RL, Rabkin SD, Wakimoto H. AI-21 * HIF-1A TARGETING IN AN ORTHOTOPIC XENOGRAFT MODEL THAT RECAPITULATES THE HYPOXIC MICROENVIRONMENT OF GLIOBLASTOMA Neuro-Oncology. 16: v5-v5. DOI: 10.1093/neuonc/nou238.21  0.348
2013 Cheema TA, Wakimoto H, Fecci PE, Ning J, Kuroda T, Jeyaretna DS, Martuza RL, Rabkin SD. Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model. Proceedings of the National Academy of Sciences of the United States of America. 110: 12006-11. PMID 23754388 DOI: 10.1073/pnas.1307935110  0.493
2013 Zhang W, Fulci G, Wakimoto H, Cheema TA, Buhrman JS, Jeyaretna DS, Stemmer Rachamimov AO, Rabkin SD, Martuza RL. Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models. Neoplasia (New York, N.Y.). 15: 591-9. PMID 23730207 DOI: 10.1593/Neo.13158  0.429
2013 Rheinbay E, Suvà ML, Gillespie SM, Wakimoto H, Patel AP, Shahid M, Oksuz O, Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S, Chi AS, Bernstein BE. An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma. Cell Reports. 3: 1567-79. PMID 23707066 DOI: 10.1016/J.Celrep.2013.04.021  0.303
2013 Las Heras F, Martuza R, Caruso P, Rincon S, Stemmer-Rachamimov A. 24-Year-old woman with an internal auditory canal mass Brain Pathology. 23: 361-362. PMID 23587143 DOI: 10.1111/Bpa.12055  0.399
2013 Passer BJ, Cheema T, Wu S, Wu CL, Rabkin SD, Martuza RL. Combination of vinblastine and oncolytic herpes simplex virus vector expressing IL-12 therapy increases antitumor and antiangiogenic effects in prostate cancer models. Cancer Gene Therapy. 20: 17-24. PMID 23138870 DOI: 10.1038/cgt.2012.75  0.413
2013 Tamura K, Wakimoto H, Agarwal AS, Rabkin SD, Bhere D, Martuza RL, Kuroda T, Kasmieh R, Shah K. Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 68-77. PMID 22929661 DOI: 10.1038/Mt.2012.175  0.439
2012 Sgubin D, Wakimoto H, Kanai R, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus counteracts the hypoxia-induced modulation of glioblastoma stem-like cells. Stem Cells Translational Medicine. 1: 322-32. PMID 23197811 DOI: 10.5966/sctm.2011-0035  0.437
2012 Barnard Z, Wakimoto H, Zaupa C, Patel AP, Klehm J, Martuza RL, Rabkin SD, Curry WT. Expression of FMS-like tyrosine kinase 3 ligand by oncolytic herpes simplex virus type I prolongs survival in mice bearing established syngeneic intracranial malignant glioma. Neurosurgery. 71: 741-8; discussion 74. PMID 22653387 DOI: 10.1227/NEU.0b013e318260fd73  0.41
2012 Kanai R, Zaupa C, Sgubin D, Antoszczyk SJ, Martuza RL, Wakimoto H, Rabkin SD. Effect of γ34.5 deletions on oncolytic herpes simplex virus activity in brain tumors. Journal of Virology. 86: 4420-31. PMID 22345479 DOI: 10.1128/JVI.00017-12  0.444
2012 Kanai R, Rabkin SD, Yip S, Sgubin D, Zaupa CM, Hirose Y, Louis DN, Wakimoto H, Martuza RL. Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. Journal of the National Cancer Institute. 104: 42-55. PMID 22173583 DOI: 10.1093/Jnci/Djr509  0.378
2012 Wakimoto H, Mohapatra G, Kanai R, Curry WT, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. Neuro-Oncology. 14: 132-44. PMID 22067563 DOI: 10.1093/Neuonc/Nor195  0.458
2012 Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 37-45. PMID 21915104 DOI: 10.1038/Mt.2011.187  0.451
2011 Cheema TA, Kanai R, Kim GW, Wakimoto H, Passer B, Rabkin SD, Martuza RL. Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7383-93. PMID 21976549 DOI: 10.1158/1078-0432.CCR-11-1762  0.444
2011 Kleijn A, Chen JW, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G. Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4484-93. PMID 21558403 DOI: 10.1158/1078-0432.Ccr-11-0575  0.452
2011 Kanai R, Wakimoto H, Martuza RL, Rabkin SD. A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3686-96. PMID 21505062 DOI: 10.1158/1078-0432.CCR-10-3142  0.397
2011 Elstner A, Stockhammer F, Nguyen-Dobinsky TN, Nguyen QL, Pilgermann I, Gill A, Guhr A, Zhang T, von Eckardstein K, Picht T, Veelken J, Martuza RL, von Deimling A, Kurtz A. Identification of diagnostic serum protein profiles of glioblastoma patients. Journal of Neuro-Oncology. 102: 71-80. PMID 20617365 DOI: 10.1007/s11060-010-0284-8  0.344
2011 Cheema TA, Wakimoto H, Rabkin S, Martuza RL. Abstract 5389: Oncolytic herpes simplex virus expressing interleukin-12 for treating glioma stem cells Cancer Research. 71: 5389-5389. DOI: 10.1158/1538-7445.Am2011-5389  0.441
2011 Zhang W, Fulci G, Rabkin SD, Zhang X, Martuza RL. Abstract 2568: Combination treatment of bevacizumab and oncolytic HSV armed with angiostatin show enhanced antitumoral and antiangiogenic effects Cancer Research. 71: 2568-2568. DOI: 10.1158/1538-7445.Am2011-2568  0.465
2010 Passer BJ, Cheema T, Zhou B, Wakimoto H, Zaupa C, Razmjoo M, Sarte J, Wu S, Wu CL, Noah JW, Li Q, Buolamwini JK, Yen Y, Rabkin SD, Martuza RL. Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication. Cancer Research. 70: 3890-5. PMID 20424118 DOI: 10.1158/0008-5472.Can-10-0155  0.392
2010 Castelo-Branco P, Passer BJ, Buhrman JS, Antoszczyk S, Marinelli M, Zaupa C, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus armed with xenogeneic homologue of prostatic acid phosphatase enhances antitumor efficacy in prostate cancer. Gene Therapy. 17: 805-10. PMID 20220784 DOI: 10.1038/Gt.2010.20  0.379
2010 Doucette TA, Kong L, Yang Y, Wei J, Wang J, Fuller GN, Heimberger AB, Rao G, Ajewung N, Kamnasaran D, Katz AM, Amankulor N, Squatrito M, Hambardzumyan D, Holland EC, ... ... Martuza RL, et al. Tumor Models (In Vivo/In Vitro) Neuro-Oncology. 12: iv130-iv136. DOI: 10.1093/Neuonc/Noq116.S20  0.421
2009 Stankovic KM, Mrugala MM, Martuza RL, Silver M, Betensky RA, Nadol JB, Stemmer-Rachamimov AO. Genetic determinants of hearing loss associated with vestibular schwannomas. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 30: 661-7. PMID 19546833 DOI: 10.1097/Mao.0B013E3181A66Ece  0.329
2009 Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Research. 69: 3472-81. PMID 19351838 DOI: 10.1158/0008-5472.Can-08-3886  0.479
2009 Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 4822-7. PMID 19264968 DOI: 10.1073/Pnas.0806647106  0.422
2009 Passer BJ, Castelo-Branco P, Buhrman JS, Varghese S, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus vectors and taxanes synergize to promote killing of prostate cancer cells. Cancer Gene Therapy. 16: 551-60. PMID 19197321 DOI: 10.1038/Cgt.2009.10  0.401
2009 Aghi MK, Carter BS, Cosgrove GR, Ojemann RG, Amin-Hanjani S, Martuza RL, Curry WT, Barker FG. Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation. Neurosurgery. 64: 56-60; discussion 60. PMID 19145156 DOI: 10.1227/01.NEU.0000330399.55586.63  0.313
2009 Aghi MK, Liu TC, Rabkin S, Martuza RL. Hypoxia enhances the replication of oncolytic herpes simplex virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 51-6. PMID 18957963 DOI: 10.1038/Mt.2008.232  0.482
2009 Kanai R, Wakimoto H, Martuza RL, Rabkin SD. Abstract C176: Combining oncolytic herpes simplex virus and chemotherapy: G47 and temozolomide synergize in killing glioma stem cells Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-C176  0.474
2008 Farrell CJ, Zaupa C, Barnard Z, Maley J, Martuza RL, Rabkin SD, Curry WT. Combination immunotherapy for tumors via sequential intratumoral injections of oncolytic herpes simplex virus 1 and immature dendritic cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7711-6. PMID 19047097 DOI: 10.1158/1078-0432.CCR-08-1364  0.479
2008 Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A. Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes. The American Journal of Pathology. 173: 1861-72. PMID 18988803 DOI: 10.2353/ajpath.2008.080376  0.328
2008 Liu TC, Castelo-Branco P, Rabkin SD, Martuza RL. Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1041-7. PMID 18388912 DOI: 10.1038/mt.2008.58  0.41
2008 Aghi MK, Liu TC, Rabkin S, Martuza RL. Glioblastoma Hypoxia Promotes Oncolytic HSV Replication in vitro and in vivo Neurosurgery. 62: 1423-1424. DOI: 10.1227/01.Neu.0000333526.39409.10  0.33
2007 Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Stemmer-Rachamimov AO, Rachamimov AS, ... ... Martuza RL, et al. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Research. 67: 9398-406. PMID 17909049 DOI: 10.1158/0008-5472.Can-07-1063  0.358
2007 Varghese S, Rabkin SD, Nielsen GP, MacGarvey U, Liu R, Martuza RL. Systemic therapy of spontaneous prostate cancer in transgenic mice with oncolytic herpes simplex viruses. Cancer Research. 67: 9371-9. PMID 17909046 DOI: 10.1158/0008-5472.CAN-07-0674  0.412
2007 Liu TC, Wakimoto H, Martuza RL, Rabkin SD. Herpes simplex virus Us3(-) mutant as oncolytic strategy and synergizes with phosphatidylinositol 3-kinase-Akt targeting molecular therapeutics. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5897-902. PMID 17908985 DOI: 10.1158/1078-0432.CCR-07-1013  0.454
2007 Jeyaretna DS, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus therapy for peripheral nerve tumors. Neurosurgical Focus. 22: E4. PMID 17613221 DOI: 10.3171/Foc.2007.22.6.5  0.455
2007 Prabhakar S, Messerli SM, Stemmer-Rachamimov AO, Liu TC, Rabkin S, Martuza R, Breakefield XO. Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta. Cancer Gene Therapy. 14: 460-7. PMID 17304235 DOI: 10.1038/Sj.Cgt.7701037  0.495
2007 Aghi M, Rabkin SD, Martuza RL. Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide. Cancer Research. 67: 440-4. PMID 17234749 DOI: 10.1158/0008-5472.CAN-06-3145  0.466
2007 Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, Rooijen NV, Stemmer-Rachamimov AO, Hochberg FH, ... ... Martuza RL, et al. Erratum: Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses (Cancer Research (2007) 67, (9398-9406)) Cancer Research. 67. DOI: 10.1158/0008-5472.Can-67-22-Cor  0.357
2006 Liu TC, Zhang T, Fukuhara H, Kuroda T, Todo T, Canron X, Bikfalvi A, Martuza RL, Kurtz A, Rabkin SD. Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6791-9. PMID 17121900 DOI: 10.1158/1078-0432.CCR-06-0263  0.494
2006 Kuroda T, Rabkin SD, Martuza RL. Effective treatment of tumors with strong beta-catenin/T-cell factor activity by transcriptionally targeted oncolytic herpes simplex virus vector. Cancer Research. 66: 10127-35. PMID 17047077 DOI: 10.1158/0008-5472.CAN-06-2744  0.378
2006 Liu TC, Zhang T, Fukuhara H, Kuroda T, Todo T, Martuza RL, Rabkin SD, Kurtz A. Oncolytic HSV armed with platelet factor 4, an antiangiogenic agent, shows enhanced efficacy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 789-97. PMID 17045531 DOI: 10.1016/j.ymthe.2006.07.011  0.501
2006 Kuroda T, Martuza RL, Todo T, Rabkin SD. Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases. Bmc Biotechnology. 6: 40. PMID 16995942 DOI: 10.1186/1472-6750-6-40  0.389
2006 Varghese S, Rabkin SD, Nielsen PG, Wang W, Martuza RL. Systemic oncolytic herpes virus therapy of poorly immunogenic prostate cancer metastatic to lung. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 2919-27. PMID 16675589 DOI: 10.1158/1078-0432.CCR-05-1187  0.41
2006 Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Human Gene Therapy. 17: 20-30. PMID 16409122 DOI: 10.1089/Hum.2006.17.20  0.457
2006 Aghi M, Rabkin S, Martuza RL. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication. Journal of the National Cancer Institute. 98: 38-50. PMID 16391370 DOI: 10.1093/Jnci/Djj003  0.39
2006 Varghese S, Rabkin SD, Liu R, Nielsen PG, Ipe T, Martuza RL. Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers. Cancer Gene Therapy. 13: 253-65. PMID 16179929 DOI: 10.1038/sj.cgt.7700900  0.419
2006 Messerli S, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Erratum: Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2 (Human Gene Therapy (January 2006) 17, 1 (20-30)) Human Gene Therapy. 17. DOI: 10.1089/Hum.2006.17.796  0.341
2006 Prabhakar S, Messerli S, Rabkin S, Martuza R, Breakefield XO. 151. Treatment of Experimental Schwannomas with HSV Recombinant and Amplicon Vectors Molecular Therapy. 13: S59. DOI: 10.1016/J.Ymthe.2006.08.174  0.461
2005 Aghi MK, Rabkin S, Martuza RL. 840 Enhanced Replication of Oncolytic Herpes Simplex Virus in Glioma Cells that Evade Temozolomide Chemotherapy through DNA Repair. Neurosurgery. 57: 408-409. PMID 28184805 DOI: 10.1093/Neurosurgery/57.2.408B  0.336
2005 Fukuhara H, Ino Y, Kuroda T, Martuza RL, Todo T. Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system. Cancer Research. 65: 10663-8. PMID 16322208 DOI: 10.1158/0008-5472.CAN-05-2534  0.374
2005 Aghi M, Martuza RL. Oncolytic viral therapies - the clinical experience. Oncogene. 24: 7802-16. PMID 16299539 DOI: 10.1038/sj.onc.1209037  0.374
2005 Fukuhara H, Martuza RL, Rabkin SD, Ito Y, Todo T. Oncolytic herpes simplex virus vector g47delta in combination with androgen ablation for the treatment of human prostate adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7886-90. PMID 16278413 DOI: 10.1158/1078-0432.CCR-05-1090  0.464
2005 Chan AW, Black P, Ojemann RG, Barker FG, Kooy HM, Lopes VV, McKenna MJ, Shrieve DC, Martuza RL, Loeffler JS. Stereotactic radiotherapy for vestibular schwannomas: favorable outcome with minimal toxicity. Neurosurgery. 57: 60-70; discussion 60. PMID 15987541 DOI: 10.1227/01.NEU.0000163091.12239.BB  0.412
2005 Mashour GA, Drissel SN, Frahm S, Farassati F, Martuza RL, Mautner VF, Kindler-Röhrborn A, Kurtz A. Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids. Oncogene. 24: 2367-74. PMID 15735744 DOI: 10.1038/sj.onc.1208425  0.341
2005 Liu R, Martuza RL, Rabkin SD. Intracarotid delivery of oncolytic HSV vector G47Delta to metastatic breast cancer in the brain. Gene Therapy. 12: 647-54. PMID 15647762 DOI: 10.1038/sj.gt.3302445  0.434
2005 Liu T, Zhang T, Fukuhara H, Kuroda T, Martuza RL, Kurtz A, Rabkin SD. 761. Dominant-Negative FGF Receptor Expression by Oncolytic HSV Vector for the Treatment of Malignant Peripheral Nerve Sheath Tumors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.302  0.465
2005 Varghese S, Rabkin SD, Nielsen PG, Liu R, Wang W, Martuza RL. 160. Systemic Oncolytic Herpes Simplex Virus Therapy of Spontaneously Arising Prostate Cancer in Transgenic TRAMP Mice|[ast]| Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.164  0.4
2004 Varghese S, Rabkin SD, Wang W, Martuza RL. 351. Enhanced Therapeutic Efficacy of a Cytokine Expressing Oncolytic Herpes Simplex Virus Against Prostate Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.303  0.374
2003 Weber DC, Chan AW, Bussiere MR, Harsh GR, Ancukiewicz M, Barker FG, Thornton AT, Martuza RL, Nadol JB, Chapman PH, Loeffler JS. Proton beam radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicity. Neurosurgery. 53: 577-86; discussion 5. PMID 12943574 DOI: 10.1227/01.Neu.0000079369.59219.C0  0.337
2002 Kurtz A, Martuza RL. Antiangiogenesis in neurofibromatosis 1. Journal of Child Neurology. 17: 578-84; discussion 6. PMID 12403556 DOI: 10.1177/088307380201700807  0.412
2001 Jorgensen TJ, Katz S, Wittmack EK, Varghese S, Todo T, Rabkin SD, Martuza RL. Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector G207 in subcutaneous tumor models of human and murine prostate cancer. Neoplasia (New York, N.Y.). 3: 451-6. PMID 11687957 DOI: 10.1038/Sj.Neo.7900193  0.469
2001 Kirn D, Martuza RL, Zwiebel J. Replication-selective virotherapy for cancer: Biological principles, risk management and future directions. Nature Medicine. 7: 781-7. PMID 11433341 DOI: 10.1038/89901  0.306
2001 Varghese S, Newsome JT, Rabkin SD, McGeagh K, Mahoney D, Nielsen P, Todo T, Martuza RL. Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates. Human Gene Therapy. 12: 999-1010. PMID 11387063 DOI: 10.1089/104303401750195944  0.324
2001 Todo T, Martuza RL, Rabkin SD, Johnson PA. Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proceedings of the National Academy of Sciences of the United States of America. 98: 6396-401. PMID 11353831 DOI: 10.1073/pnas.101136398  0.444
2001 Toda M, Martuza RL, Rabkin SD. Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine. Gene Therapy. 8: 332-9. PMID 11313808 DOI: 10.1038/Sj.Gt.3301392  0.541
2001 Mashour GA, Moulding HD, Chahlavi A, Khan GA, Rabkin SD, Martuza RL, Driever PH, Kurtz A, Chalavi A. Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model. Experimental Neurology. 169: 64-71. PMID 11312559 DOI: 10.1006/exnr.2001.7641  0.388
2001 Mashour GA, Ratner N, Khan GA, Wang HL, Martuza RL, Kurtz A. The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells. Oncogene. 20: 97-105. PMID 11244508 DOI: 10.1038/sj.onc.1204026  0.431
2001 Todo T, Martuza RL, Dallman MJ, Rabkin SD. In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity. Cancer Research. 61: 153-61. PMID 11196154  0.363
2001 Barker FG, McKenna M, Poe D, Nadol J, Chapman P, Martuza R, Ojemann RG. 790 Pediatric Acoustic Neuromas: NF2 and Sporadic Tumors Neurosurgery. 49: 533-533. DOI: 10.1097/00006123-200108000-00154  0.396
2001 Mashour GA, Moulding HD, Chalavi A, Khan GA, Rabkin SD, Martuza RL, Driever PH, Kurtz A. Therapeutic Efficacy of G207 in a Novel Peripheral Nerve Sheath Tumor Model Experimental Neurology. 169: 501. DOI: 10.1006/exnr.2001.7694  0.375
2000 Todo T, Feigenbaum F, Rabkin SD, Lakeman F, Newsome JT, Johnson PA, Mitchell E, Belliveau D, Ostrove JM, Martuza RL. Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 588-95. PMID 11124059 DOI: 10.1006/mthe.2000.0200  0.376
2000 Toda M, Martuza RL, Rabkin SD. Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 324-9. PMID 11020347 DOI: 10.1006/mthe.2000.0130  0.589
2000 Sandhu FA, Martuza RL. Craniofacial hemangiopericytoma associated with oncogenic osteomalacia: case report. Journal of Neuro-Oncology. 46: 241-7. PMID 10902855 DOI: 10.1023/A:1006352106762  0.375
2000 Todo T, Rabkin SD, Martuza RL. Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors. Cancer Gene Therapy. 7: 939-46. PMID 10880026 DOI: 10.1038/sj.cgt.7700182  0.463
2000 Markert JM, Medlock MD, Rabkin SD, Gillespie GY, Todo T, Hunter WD, Palmer CA, Feigenbaum F, Tornatore C, Tufaro F, Martuza RL. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Therapy. 7: 867-74. PMID 10845725 DOI: 10.1038/Sj.Gt.3301205  0.418
2000 Martuza RL. Conditionally replicating herpes vectors for cancer therapy. The Journal of Clinical Investigation. 105: 841-6. PMID 10749560 DOI: 10.1172/JCI9744  0.483
2000 Sundaresan P, Hunter WD, Martuza RL, Rabkin SD. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice. Journal of Virology. 74: 3832-41. PMID 10729157 DOI: 10.1128/JVI.74.8.3832-3841.2000  0.364
1999 Chahlavi A, Todo T, Martuza RL, Rabkin SD. Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma. Neoplasia (New York, N.Y.). 1: 162-9. PMID 10933051 DOI: 10.1038/Sj.Neo.7900016  0.402
1999 Todo T, Rabkin SD, Chahlavi A, Martuza RL. Corticosteroid administration does not affect viral oncolytic activity, but inhibits antitumor immunity in replication-competent herpes simplex virus tumor therapy. Human Gene Therapy. 10: 2869-78. PMID 10584932 DOI: 10.1089/10430349950016591  0.44
1999 Todo T, Rabkin SD, Sundaresan P, Wu A, Meehan KR, Herscowitz HB, Martuza RL. Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Human Gene Therapy. 10: 2741-55. PMID 10584921 DOI: 10.1089/10430349950016483  0.456
1999 Chahlavi A, Rabkin SD, Todo T, Sundaresan P, Martuza RL. Effect of prior exposure to herpes simplex virus 1 on viral vector-mediated tumor therapy in immunocompetent mice Gene Therapy. 6: 1751-1758. PMID 10516725 DOI: 10.1038/sj.gt.3301003  0.476
1999 Walker JR, McGeagh KG, Sundaresan P, Jorgensen TJ, Rabkin SD, Martuza RL. Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207. Human Gene Therapy. 10: 2237-43. PMID 10498254 DOI: 10.1089/10430349950017211  0.414
1999 Miyatake SI, Tani S, Feigenbaum F, Sundaresan P, Toda H, Narumi O, Kikuchi H, Hashimoto N, Hangai M, Martuza RL, Rabkin SD. Hepatoma-specific antitumor activity of an albumin enhancer/promoter regulated herpes simplex virus in vivo. Gene Therapy. 6: 564-72. PMID 10476216 DOI: 10.1038/sj.gt.3300861  0.387
1999 Mashour GA, Wang HL, Cabal-Manzano R, Wellstein A, Martuza RL, Kurtz A. Aberrant cutaneous expression of the angiogenic factor midkine is associated with neurofibromatosis type-1. The Journal of Investigative Dermatology. 113: 398-402. PMID 10469340 DOI: 10.1046/J.1523-1747.1999.00699.X  0.336
1999 Hunter WD, Martuza RL, Feigenbaum F, Todo T, Mineta T, Yazaki T, Toda M, Newsome JT, Platenberg RC, Manz HJ, Rabkin SD. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates. Journal of Virology. 73: 6319-26. PMID 10400723 DOI: 10.1128/Jvi.73.8.6319-6326.1999  0.497
1999 Toda M, Rabkin SD, Kojima H, Martuza RL. Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity. Human Gene Therapy. 10: 385-93. PMID 10048391 DOI: 10.1089/10430349950018832  0.609
1999 Walker JR, Sundaresan P, Rabkin SD, Lynch JH, Martuza RL. A Novel New Treatment For Prostate Cancer With A Conditionally Replicating Herpes Simplex-1 Virus, G207 The Journal of Urology. 125. DOI: 10.1097/00005392-199904010-00501  0.307
1998 Toda M, Rabkin SD, Martuza RL. Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1. Human Gene Therapy. 9: 2177-85. PMID 9794202 DOI: 10.1089/hum.1998.9.15-2177  0.584
1998 Toda M, Martuza RL, Kojima H, Rabkin SD. In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity. Journal of Immunology (Baltimore, Md. : 1950). 160: 4457-64. PMID 9574551  0.52
1997 Martuza RL. Act locally, think globally. Nature Medicine. 3: 1323. PMID 9396599 DOI: 10.1038/nm1297-1323  0.364
1997 Miyatake S, Martuza RL, Rabkin SD. Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma. Cancer Gene Therapy. 4: 222-8. PMID 9253507  0.311
1997 Miyatake S, Iyer A, Martuza RL, Rabkin SD. Transcriptional targeting of herpes simplex virus for cell-specific replication. Journal of Virology. 71: 5124-32. PMID 9188579 DOI: 10.1128/Jvi.71.7.5124-5132.1997  0.373
1997 Menon AG, Rutter JL, von Sattel JP, Synder H, Murdoch C, Blumenfeld A, Martuza RL, von Deimling A, Gusella JF, Houseal TW. Frequent loss of chromosome 14 in atypical and malignant meningioma: identification of a putative 'tumor progression' locus. Oncogene. 14: 611-6. PMID 9053860 DOI: 10.1038/Sj.Onc.1200853  0.405
1996 Yazaki T, Nakai Y, Uyemura K, Martuza RL, Rabkin SD. 1308 Defective herpes simplex virus vectors for the study of l1 gene transfer into the nervous system Neuroscience Research. 25: S143. DOI: 10.1016/0168-0102(96)88957-7  0.526
1995 Mineta T, Tabuchi K, Martuza RL. [Gene therapy for brain tumors: experimental treatment of malignant brain tumors using recombinant herpes simplex virus type 1 (series 7)]. No Shinkei Geka. Neurological Surgery. 23: 285-92. PMID 7739766  0.338
1995 Yazaki T, Manz HJ, Rabkin SD, Martuza RL. Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1. Cancer Research. 55: 4752-6. PMID 7585498  0.307
1995 Mineta T, Rabkin SD, Yazaki T, Hunter WD, Martuza RL. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nature Medicine. 1: 938-43. PMID 7585221 DOI: 10.1038/Nm0995-938  0.383
1995 Yazaki T, Takamiya Y, Costello PC, Mineta T, Menon AG, Rabkin SD, Martuza RL. Inhibition of angiogenesis and growth of human non-malignant and malignant meningiomas by TNP-470. Journal of Neuro-Oncology. 23: 23-9. PMID 7542695 DOI: 10.1007/Bf01058456  0.452
1994 Mineta T, Markert JM, Takamiya Y, Coen DM, Rabkin SD, Martuza RL. CNS tumor therapy by attenuated herpes simplex viruses. Gene Therapy. 1: S78. PMID 8542424  0.335
1994 Takamiya Y, Brem H, Ojeifo J, Mineta T, Martuza RL. AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo. Neurosurgery. 34: 869-75; discussion 8. PMID 8052385 DOI: 10.1227/00006123-199405000-00013  0.444
1994 Mineta T, Rabkin SD, Martuza RL. Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant. Cancer Research. 54: 3963-6. PMID 8033122  0.375
1993 Takamiya Y, Friedlander RM, Brem H, Malick A, Martuza RL. Inhibition of angiogenesis and growth of human nerve-sheath tumors by AGM-1470. Journal of Neurosurgery. 78: 470-6. PMID 8433151 DOI: 10.3171/Jns.1993.78.3.0470  0.387
1993 Takamiya Y, Short MP, Moolten FL, Fleet C, Mineta T, Breakefield XO, Martuza RL. An experimental model of retrovirus gene therapy for malignant brain tumors. Journal of Neurosurgery. 79: 104-10. PMID 8391069 DOI: 10.3171/jns.1993.79.1.0104  0.41
1993 Markert JM, Malick A, Coen DM, Martuza RL. Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir. Neurosurgery. 32: 597-603. PMID 8386343 DOI: 10.1227/00006123-199304000-00016  0.389
1992 Poon WS, Schomacker KT, Deutsch TF, Martuza RL. Laser-induced fluorescence: experimental intraoperative delineation of tumor resection margins. Journal of Neurosurgery. 76: 679-86. PMID 1545262 DOI: 10.3171/jns.1992.76.4.0679  0.35
1992 Lee JK, Sobel RA, Chiocca EA, Kim TS, Martuza RL. Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse. Journal of Neuro-Oncology. 14: 101-12. PMID 1432035 DOI: 10.1007/Bf00177613  0.428
1992 Martuza RL. Molecular neurosurgery for glial and neuronal disorders. Stereotactic and Functional Neurosurgery. 59: 92-9. PMID 1338233 DOI: 10.1159/000098923  0.342
1992 Takamiya Y, Short MP, Ezzeddine ZD, Moolten FL, Breakefield XO, Martuza RL. Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells. Journal of Neuroscience Research. 33: 493-503. PMID 1335091 DOI: 10.1002/jnr.490330316  0.466
1992 Markert JM, Coen DM, Malick A, Mineta T, Martuza RL. Expanded spectrum of viral therapy in the treatment of nervous system tumors. Journal of Neurosurgery. 77: 590-4. PMID 1326612 DOI: 10.3171/Jns.1992.77.4.0590  0.494
1992 von Deimling A, Louis DN, von Ammon K, Petersen I, Hoell T, Chung RY, Martuza RL, Schoenfeld DA, YaÅŸargil MG, Wiestler OD. Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. Journal of Neurosurgery. 77: 295-301. PMID 1320666 DOI: 10.3171/Jns.1992.77.2.0295  0.301
1991 Fontaine B, Rouleau GA, Seizinger BR, Menon AG, Jewell AF, Martuza RL, Gusella JF. Molecular genetics of neurofibromatosis 2 and related tumors (acoustic neuroma and meningioma). Annals of the New York Academy of Sciences. 615: 338-43. PMID 2039155 DOI: 10.1111/J.1749-6632.1991.Tb37776.X  0.398
1991 Steichen JD, Weiss MJ, Elmaleh DR, Martuza RL. Enhanced in vitro uptake and retention of 3H-tetraphenylphosphonium by nervous system tumor cells. Journal of Neurosurgery. 74: 116-22. PMID 1984490 DOI: 10.3171/jns.1991.74.1.0116  0.442
1991 Martuza RL, Malick A, Markert JM, Ruffner KL, Coen DM. Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science (New York, N.Y.). 252: 854-6. PMID 1851332 DOI: 10.1126/Science.1851332  0.419
1991 Halliday AL, Sobel RA, Martuza RL. Benign spinal nerve sheath tumors: their occurrence sporadically and in neurofibromatosis types 1 and 2. Journal of Neurosurgery. 74: 248-53. PMID 1846409 DOI: 10.3171/Jns.1991.74.2.0248  0.383
1991 Chung R, Whaley J, Kley N, Anderson K, Louis D, Menon A, Hettlich C, Freiman R, Hedley-Whyte ET, Martuza R. TP53 gene mutations and 17p deletions in human astrocytomas. Genes, Chromosomes & Cancer. 3: 323-31. PMID 1686725 DOI: 10.1002/Gcc.2870030502  0.404
1991 Fontaine B, Sanson M, Delattre O, Menon AG, Rouleau GA, Seizinger BR, Jewell AF, Hanson MP, Aurias A, Martuza RL. Parental origin of chromosome 22 loss in sporadic and NF2 neuromas. Genomics. 10: 280-3. PMID 1675196 DOI: 10.1016/0888-7543(91)90513-E  0.324
1991 Ezzeddine ZD, Martuza RL, Platika D, Short MP, Malick A, Choi B, Breakefield XO. Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. The New Biologist. 3: 608-14. PMID 1655012  0.31
1990 Lee JK, Kim TS, Chiocca EA, Medhkour A, Martuza RL. Growth of human schwannomas in the subrenal capsule of the nude mouse. Neurosurgery. 26: 598-605. PMID 2330081 DOI: 10.1097/00006123-199004000-00007  0.428
1990 Logan JA, Seizinger BR, Atkins L, Martuza RL. Loss of the Y chromosome in meningiomas. A molecular genetic approach. Cancer Genetics and Cytogenetics. 45: 41-7. PMID 2302684 DOI: 10.1016/0165-4608(90)90064-H  0.313
1990 Short MP, Choi BC, Lee JK, Malick A, Breakefield XO, Martuza RL. Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line. Journal of Neuroscience Research. 27: 427-39. PMID 2129047 DOI: 10.1002/Jnr.490270322  0.369
1990 Lee JK, Choi B, Sobel RA, Chiocca EA, Martuza RL. Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone. Journal of Neurosurgery. 73: 429-35. PMID 1696626 DOI: 10.3171/Jns.1990.73.3.0429  0.393
1990 Halliday AL, Sobel RA, Martuza RL. BENIGN INTRASPINAL NERVE SHEATH TUMORS (SNST) Journal of Neuropathology and Experimental Neurology. 49: 320. DOI: 10.1097/00005072-199005000-00182  0.372
1989 Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma. Acta Neuropathologica. 78: 332-5. PMID 2763807 DOI: 10.1007/Bf00687765  0.416
1989 el-Azouzi M, Chung RY, Farmer GE, Martuza RL, Black PM, Rouleau GA, Hettlich C, Hedley-Whyte ET, Zervas NT, Panagopoulos K. Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas. Proceedings of the National Academy of Sciences of the United States of America. 86: 7186-90. PMID 2571151 DOI: 10.1073/Pnas.86.18.7186  0.379
1989 Medhkour A, Van Roey M, Sobel RA, Fingert HJ, Lee J, Martuza RL. Implantation of human meningiomas into the subrenal capsule of the nude mouse. A model for studies of tumor growth. Journal of Neurosurgery. 71: 545-50. PMID 2477514 DOI: 10.3171/Jns.1989.71.4.0545  0.396
1988 Kostron H, Swartz MR, Martuza RL. Photodynamic therapy is potentiated by Co60 and intratumoral injection of hematoporphyrin derivative. Journal of Neuro-Oncology. 6: 185-91. PMID 2976084 DOI: 10.1007/BF02327395  0.383
1988 Martuza RL, Seizinger BR, Jacoby LB, Rouleau GA, Gusella JF. The molecular biology of human glial tumors. Trends in Neurosciences. 11: 22-7. PMID 2469150 DOI: 10.1016/0166-2236(88)90045-8  0.454
1987 Nadol JB, Levine R, Ojemann RG, Martuza RL, Montgomery WW, de Sandoval PK. Preservation of hearing in surgical removal of acoustic neuromas of the internal auditory canal and cerebellar pontine angle. The Laryngoscope. 97: 1287-94. PMID 3499554 DOI: 10.1288/00005537-198711000-00007  0.347
1987 Seizinger BR, Martuza RL, Rouleau G, Breakefield XO, Gusella JF. Models for inherited susceptibility to cancer in the nervous system: a molecular-genetic approach to neurofibromatosis. Developmental Neuroscience. 9: 144-53. PMID 3119309 DOI: 10.1159/000111618  0.414
1987 Seizinger BR, Rouleau G, Ozelius LJ, Lane AH, St George-Hyslop P, Huson S, Gusella JF, Martuza RL. Common pathogenetic mechanism for three tumor types in bilateral acoustic neurofibromatosis. Science (New York, N.Y.). 236: 317-9. PMID 3105060 DOI: 10.1126/Science.3105060  0.365
1987 Seizinger BR, de la Monte S, Atkins L, Gusella JF, Martuza RL. Molecular genetic approach to human meningioma: loss of genes on chromosome 22. Proceedings of the National Academy of Sciences of the United States of America. 84: 5419-23. PMID 3037550 DOI: 10.1073/Pnas.84.15.5419  0.362
1986 Kostron H, Swartz MR, Miller DC, Martuza RL. The interaction of hematoporphyrin derivative, light, and ionizing radiation in a rat glioma model. Cancer. 57: 964-70. PMID 3943032 DOI: 10.1002/1097-0142(19860301)57:5<964::Aid-Cncr2820570515>3.0.Co;2-S  0.348
1986 Brockes JP, Breakefield XO, Martuza RL. Glial growth factor-like activity in Schwann cell tumors. Annals of Neurology. 20: 317-22. PMID 3767316 DOI: 10.1002/Ana.410200308  0.421
1986 Cohen AM, Wood WC, Bamberg M, Martuza R. Cytotoxicity of human brain tumors by hematoporphyrin derivative. The Journal of Surgical Research. 41: 81-3. PMID 3747501 DOI: 10.1016/0022-4804(86)90012-0  0.399
1986 Jay JR, MacLaughlin DT, Badger TM, Miller DC, Martuza RL. Hormonal modulation of Schwann cell tumors. I. The effects of estradiol and tamoxifen on methylnitrosourea-induced rat Schwann cell tumors. Annals of the New York Academy of Sciences. 486: 371-82. PMID 3105400 DOI: 10.1111/J.1749-6632.1986.Tb48090.X  0.426
1986 Jacoby LB, Martuza RL. DNA transfection analysis of the tumors of neurofibromatosis. Annals of the New York Academy of Sciences. 486: 333-5. PMID 3032057 DOI: 10.1111/J.1749-6632.1986.Tb48086.X  0.377
1986 Steichen JD, Dashner K, Martuza RL. Distribution of hematoporphyrin derivative in canine glioma following intraneoplastic and intraperitoneal injection. Journal of Neurosurgery. 65: 364-9. PMID 2942650 DOI: 10.3171/jns.1986.65.3.0364  0.368
1986 Kostron H, Bellnier DA, Lin CW, Swartz MR, Martuza RL. Distribution, retention, and phototoxicity of hematoporphyrin derivative in a rat glioma. Intraneoplastic versus intraperitoneal injection. Journal of Neurosurgery. 64: 768-74. PMID 2939204 DOI: 10.3171/jns.1986.64.5.0768  0.402
1985 Jay JR, MacLaughlin DT, Riley KR, Martuza RL. Modulation of meningioma cell growth by sex steroid hormones in vitro. Journal of Neurosurgery. 62: 757-62. PMID 3989596 DOI: 10.3171/jns.1985.62.5.0757  0.353
1985 Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL. Meningioma: analysis of recurrence and progression following neurosurgical resection. Journal of Neurosurgery. 62: 18-24. PMID 3964853 DOI: 10.3171/jns.1985.62.1.0018  0.354
1983 Martuza RL. Genetics in neuro-oncology. Clinical Neurosurgery. 31: 417-40. PMID 6437720 DOI: 10.1093/Neurosurgery/31.Cn_Suppl_1.417  0.455
1982 Martuza RL, Ojemann RG. Bilateral acoustic neuromas: clinical aspects, pathogenesis, and treatment. Neurosurgery. 10: 1-12. PMID 7057963 DOI: 10.1227/00006123-198201000-00001  0.343
1981 Martuza RL, MacLaughlin DT, Ojemann RG. Specific estradiol binding in schwannomas, meningiomas, and neurofibromas. Neurosurgery. 9: 665-71. PMID 7198726 DOI: 10.1227/00006123-198112000-00009  0.317
1976 Stewart RM, Martuza RL, Baldessarini RJ, Kornblith PL. Glutamate accumulation by human gliomas and meningiomas in tissue culture. Brain Research. 118: 441-52. PMID 1009428 DOI: 10.1016/0006-8993(76)90311-5  0.334
1976 Phillips JP, Sujatanond M, Martuza RL, Quindlen EA, Wood WC, Kornblith PL, Dohan FC. Cytotoxic antibodies in preoperative glioma patients: a diagnostic assay. Acta Neurochirurgica. 35: 43-52. PMID 961503 DOI: 10.1007/BF01405931  0.362
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