Year |
Citation |
Score |
2020 |
Liang Y, Zeng D, You Y, Ma B, Li X, Chen T. Designing Dihydrofolate Reductase Inhibitors as X-ray Radiosensitizers to Reverse Radioresistance of Cervical Cancer. Acs Medicinal Chemistry Letters. 11: 1421-1428. PMID 32676149 DOI: 10.1021/Acsmedchemlett.0C00105 |
0.316 |
|
2020 |
Yang F, Huang J, Liu H, Lin W, Li X, Zhu X, Chen T. Lentinan-functionalized selenium nanosystems with high permeability infiltrate solid tumors by enhancing transcellular transport. Nanoscale. PMID 32614349 DOI: 10.1039/D0Nr02171G |
0.314 |
|
2019 |
Huang J, Liu Y, Liu T, Chang Y, Chen T, Li X. Dual-targeting nanotherapeutics antagonize hyperinsulinemia-promoted tumor growth via activating cell autophagy. Journal of Materials Chemistry. B. PMID 31593205 DOI: 10.1039/C9Tb01197H |
0.366 |
|
2018 |
Huang W, Liang Y, Sang C, Mei C, Li X, Chen T. Therapeutic nanosystems co-deliver anticancer drugs and oncogene SiRNA to achieve synergetic precise cancer chemo-gene therapy. Journal of Materials Chemistry. B. 6: 3013-3022. PMID 32254336 DOI: 10.1039/C8Tb00004B |
0.31 |
|
2018 |
Tan Q, Peng L, Huang Y, Huang W, Bai W, Shi L, Li X, Chen T. Structure-activity Relationship Analysis on Antioxidant and Anticancer Actions of Theaflavins on Human Colon Cancer Cells. Journal of Agricultural and Food Chemistry. PMID 30474978 DOI: 10.1021/Acs.Jafc.8B05369 |
0.365 |
|
2018 |
Lin H, Wang Y, Lai H, Li X, Chen T. Iron(II) Polypyridyl Complexes Inhibit Glioblastoma Tumor Growth and Enhance TRAIL-induced Cell Apoptosis. Chemistry, An Asian Journal. PMID 29963768 DOI: 10.1002/Asia.201800862 |
0.392 |
|
2018 |
Li X, Zhang H, Chan L, Liu C, Chen T. Nutritional Available Seleno-amino Acid Derivative Antagonizes Cisplatin-induced Nephrotoxicity Through Inhibition of ROS-mediated Signaling Pathways. Journal of Agricultural and Food Chemistry. PMID 29779385 DOI: 10.1021/Acs.Jafc.8B01876 |
0.396 |
|
2018 |
Lai H, Fu X, Sang C, Hou L, Feng P, Li X, Chen T. Selenadiazole derivatives inhibit angiogenesis-mediated human breast tumor growth through suppressing VEGFR2-mediated ERK and AKT signaling pathway. Chemistry, An Asian Journal. PMID 29575811 DOI: 10.1002/Asia.201800110 |
0.364 |
|
2017 |
Liu C, Fu Y, Li CE, Chen T, Li X. Phycocyanin-functionalized selenium nanoparticles reverse palmitic acid-induced pancreatic beta cells apoptosis by enhancing cellular uptake and blocking ROS-mediated mitochondria dysfunction. Journal of Agricultural and Food Chemistry. PMID 28510423 DOI: 10.1021/Acs.Jafc.7B00896 |
0.42 |
|
2017 |
Zhao J, Zeng D, Liu Y, Luo Y, Ji S, Li X, Chen T. Selenadiazole derivatives antagonize hyperglycemia-induced drug resistance in breast cancer cells by activation of AMPK pathways. Metallomics : Integrated Biometal Science. PMID 28374040 DOI: 10.1039/C7Mt00001D |
0.404 |
|
2017 |
Du Y, Li H, Chen B, Lai H, Li X, Chen T. Selenadiazole derivatives antagonize glucocorticoid-induced osteoblasts cells apoptosis by blocking ROS-mediated signaling, a new anti-osteoporosis strategy Rsc Advances. 7: 29656-29664. DOI: 10.1039/C7Ra01306J |
0.381 |
|
2016 |
Huang W, Wu H, Li X, Chen T. Facile one-pot synthesis of tellurium nanorods as antioxidant and anticancer agents. Chemistry, An Asian Journal. PMID 27325381 DOI: 10.1002/Asia.201600757 |
0.337 |
|
2016 |
Tutino GE, Yang WY, Li X, Li WH, Zhang YY, Guo XH, Luk AO, Yeung RO, Yin JM, Ozaki R, So WY, Ma RC, Ji LN, Kong AP, Weng JP, et al. A multicentre demonstration project to evaluate the effectiveness and acceptability of the web-based Joint Asia Diabetes Evaluation (JADE) programme with or without nurse support in Chinese patients with Type 2 diabetes. Diabetic Medicine : a Journal of the British Diabetic Association. PMID 27278933 DOI: 10.1111/dme.13164 |
0.324 |
|
2016 |
Fu X, Yang Y, Li X, Lai H, Huang Y, He L, Zheng W, Chen T. RGD Peptide-conjugated Selenium Nanoparticles: Antiangiogenesis by Suppressing VEGF-VEGFR2-ERK/AKT Pathway. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26961468 DOI: 10.1016/J.Nano.2016.01.012 |
0.34 |
|
2016 |
Wang Z, Seow WJ, Shiraishi K, Hsiung CA, Matsuo K, Liu J, Chen K, Yamji T, Yang Y, Chang IS, Wu C, Hong YC, Burdett L, Wyatt K, Chung CC, ... Li X, et al. Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women. Human Molecular Genetics. PMID 26732429 DOI: 10.1093/Hmg/Ddv494 |
0.324 |
|
2015 |
Wang Y, Li W, Yang Y, Zeng Q, Wong KH, Li X, Chen T. An integrin-targeting nanosystem as a carrier of the selenadiazole derivative to induce ROS-mediated apoptosis in bladder cancer cells, from rational design to action mechanisms. Journal of Materials Chemistry. B. 3: 9374-9382. PMID 32262936 DOI: 10.1039/C5Tb01929J |
0.371 |
|
2015 |
Li X, Li J, Hu X, Huang L, Xiao J, Chan J, Mi K. Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility. Scientific Reports. 5: 16130. PMID 26607739 DOI: 10.1038/srep16130 |
0.347 |
|
2015 |
Luk AO, Li X, Zhang Y, Guo X, Jia W, Li W, Weng J, Yang W, Chan WB, Ozaki R, Tsang CC, Mukhopadhyay M, Ojha AK, Hong EG, Yoon KH, et al. Quality of care in patients with diabetic kidney disease in Asia: The Joint Asia Diabetes Evaluation (JADE) Registry. Diabetic Medicine : a Journal of the British Diabetic Association. PMID 26511783 DOI: 10.1111/Dme.13014 |
0.321 |
|
2015 |
Luk AO, Fu WC, Li X, Ozaki R, Chung HH, Wong RY, So WY, Chow FC, Chan JC. The Clinical Utility of SUDOSCAN in Chronic Kidney Disease in Chinese Patients with Type 2 Diabetes. Plos One. 10: e0134981. PMID 26270544 DOI: 10.1371/journal.pone.0134981 |
0.319 |
|
2015 |
Hu X, Li X, Huang L, Chan J, Chen Y, Deng H, Mi K. Quantitative proteomics reveals novel insights into isoniazid susceptibility in mycobacteria mediated by a universal stress protein. Journal of Proteome Research. 14: 1445-54. PMID 25664397 DOI: 10.1021/pr5011058 |
0.353 |
|
2015 |
Liu Y, Luo Y, Li X, Zheng W, Chen T. Rational design of selenadiazole derivatives to antagonize hyperglycemia-induced drug resistance in cancer cells. Chemistry, An Asian Journal. 10: 642-52. PMID 25641920 DOI: 10.1002/Asia.201403409 |
0.381 |
|
2015 |
Li XL, Wong YS, Xu G, Chan JC. Selenium-enriched Spirulina protects INS-1E pancreatic beta cells from human islet amyloid polypeptide-induced apoptosis through suppression of ROS-mediated mitochondrial dysfunction and PI3/AKT pathway. European Journal of Nutrition. 54: 509-22. PMID 25112514 DOI: 10.1007/S00394-014-0732-X |
0.545 |
|
2015 |
Ma L, Fu Y, Yu L, Li X, Zheng W, Chen T. Ruthenium complexes as inhibitors of human islet amyloid polypeptide aggregation, an effect that prevents beta cell apoptosis Rsc Advances. 5: 17405-17412. DOI: 10.1039/C4Ra15152F |
0.376 |
|
2014 |
Yu B, Li X, Zheng W, Feng Y, Wong YS, Chen T. pH-responsive cancer-targeted selenium nanoparticles: a transformable drug carrier with enhanced theranostic effects. Journal of Materials Chemistry. B. 2: 5409-5418. PMID 32261761 DOI: 10.1039/C4Tb00399C |
0.392 |
|
2014 |
Li X, Tao J, Hu X, Chan J, Xiao J, Mi K. A bacterial hemerythrin-like protein MsmHr inhibits the SigF-dependent hydrogen peroxide response in mycobacteria. Frontiers in Microbiology. 5: 800. PMID 25642228 DOI: 10.3389/fmicb.2014.00800 |
0.384 |
|
2014 |
Yang F, Wong KH, Yang Y, Li X, Jiang J, Zheng W, Wu H, Chen T. Purification and in vitro antioxidant activities of tellurium-containing phycobiliproteins from tellurium-enriched Spirulina platensis. Drug Design, Development and Therapy. 8: 1789-800. PMID 25336922 DOI: 10.2147/Dddt.S62530 |
0.327 |
|
2014 |
Cao W, Li X, Zheng S, Zheng W, Wong YS, Chen T. Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk. Oncotarget. 5: 7431-45. PMID 25277183 DOI: 10.18632/Oncotarget.2008 |
0.416 |
|
2014 |
Venkataswamy MM, Ng TW, Kharkwal SS, Carreño LJ, Johnson AJ, Kunnath-Velayudhan S, Liu Z, Bittman R, Jervis PJ, Cox LR, Besra GS, Wen X, Yuan W, Tsuji M, Li X, et al. Improving Mycobacterium bovis bacillus Calmette-Guèrin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells. Plos One. 9: e108383. PMID 25255287 DOI: 10.1371/Journal.Pone.0108383 |
0.38 |
|
2014 |
Ma L, Li X, Wang Y, Zheng W, Chen T. Cu(II) inhibits hIAPP fibrillation and promotes hIAPP-induced beta cell apoptosis through induction of ROS-mediated mitochondrial dysfunction. Journal of Inorganic Biochemistry. 140: 143-52. PMID 25108186 DOI: 10.1016/J.Jinorgbio.2014.07.002 |
0.343 |
|
2014 |
Liang YW, Zheng J, Li X, Zheng W, Chen T. Selenadiazole derivatives as potent thioredoxin reductase inhibitors that enhance the radiosensitivity of cancer cells. European Journal of Medicinal Chemistry. 84: 335-42. PMID 25036792 DOI: 10.1016/J.Ejmech.2014.07.032 |
0.386 |
|
2014 |
Li X, Ma L, Zheng W, Chen T. Inhibition of islet amyloid polypeptide fibril formation by selenium-containing phycocyanin and prevention of beta cell apoptosis. Biomaterials. 35: 8596-604. PMID 25034964 DOI: 10.1016/J.Biomaterials.2014.06.056 |
0.377 |
|
2014 |
Fan C, Zheng W, Fu X, Li X, Wong YS, Chen T. Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling. Oncotarget. 5: 2853-63. PMID 24797310 DOI: 10.18632/Oncotarget.1854 |
0.377 |
|
2014 |
Xie Q, Liu S, Li X, Wu Q, Luo Z, Fu X, Cao W, Lan G, Li D, Zheng W, Chen T. Dinuclear zinc(II) complexes containing (benzimidazol-2-yl)benzene that overcome drug resistance in hepatocellular carcinoma cells through induction of mitochondria fragmentation. Dalton Transactions (Cambridge, England : 2003). 43: 6973-6. PMID 24668337 DOI: 10.1039/C4Dt00198B |
0.304 |
|
2014 |
Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, ... ... Li X, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/Ng.2897 |
0.338 |
|
2014 |
Li XQ, Cheuk W, Lam PW, Wang Z, Loong F, Yeong ML, Browett P, McCall J, Chan JK. Inflammatory pseudotumor-like follicular dendritic cell tumor of liver and spleen: granulomatous and eosinophil-rich variants mimicking inflammatory or infective lesions. The American Journal of Surgical Pathology. 38: 646-53. PMID 24503752 DOI: 10.1097/PAS.0000000000000170 |
0.359 |
|
2013 |
Li Y, Li X, Zheng W, Fan C, Zhang Y, Chen T. Functionalized selenium nanoparticles with nephroprotective activity, the important roles of ROS-mediated signaling pathways. Journal of Materials Chemistry. B. 1: 6365-6372. PMID 32261335 DOI: 10.1039/C3Tb21168A |
0.389 |
|
2013 |
Wu H, Zhu H, Li X, Liu Z, Zheng W, Chen T, Yu B, Wong KH. Induction of apoptosis and cell cycle arrest in A549 human lung adenocarcinoma cells by surface-capping selenium nanoparticles: an effect enhanced by polysaccharide-protein complexes from Polyporus rhinocerus. Journal of Agricultural and Food Chemistry. 61: 9859-66. PMID 24053442 DOI: 10.1021/Jf403564S |
0.368 |
|
2013 |
Sham HP, Yu EY, Gulen MF, Bhinder G, Stahl M, Chan JM, Brewster L, Morampudi V, Gibson DL, Hughes MR, McNagny KM, Li X, Vallance BA. SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens. Plos Pathogens. 9: e1003539. PMID 23950714 DOI: 10.1371/journal.ppat.1003539 |
0.342 |
|
2013 |
Su J, Lai H, Chen J, Li L, Wong YS, Chen T, Li X. Natural borneol, a monoterpenoid compound, potentiates selenocystine-induced apoptosis in human hepatocellular carcinoma cells by enhancement of cellular uptake and activation of ROS-mediated DNA damage. Plos One. 8: e63502. PMID 23700426 DOI: 10.1371/Journal.Pone.0063502 |
0.323 |
|
2013 |
Liu C, Liu Z, Li M, Li X, Wong YS, Ngai SM, Zheng W, Zhang Y, Chen T. Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase. Plos One. 8: e53945. PMID 23342042 DOI: 10.1371/Journal.Pone.0053945 |
0.415 |
|
2013 |
Zhang Y, Li X, Huang Z, Zheng W, Fan C, Chen T. Enhancement of cell permeabilization apoptosis-inducing activity of selenium nanoparticles by ATP surface decoration. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 74-84. PMID 22542821 DOI: 10.1016/J.Nano.2012.04.002 |
0.351 |
|
2012 |
Zheng S, Li X, Zhang Y, Xie Q, Wong YS, Zheng W, Chen T. PEG-nanolized ultrasmall selenium nanoparticles overcome drug resistance in hepatocellular carcinoma HepG2 cells through induction of mitochondria dysfunction. International Journal of Nanomedicine. 7: 3939-49. PMID 22915845 DOI: 10.2147/Ijn.S30940 |
0.372 |
|
2012 |
Liu W, Li X, Wong YS, Zheng W, Zhang Y, Cao W, Chen T. Selenium nanoparticles as a carrier of 5-fluorouracil to achieve anticancer synergism. Acs Nano. 6: 6578-91. PMID 22823110 DOI: 10.1021/Nn202452C |
0.417 |
|
2012 |
Sui Y, Zhao HL, Wong VC, Brown N, Li XL, Kwan AK, Hui HL, Ziea ET, Chan JC. A systematic review on use of Chinese medicine and acupuncture for treatment of obesity. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 13: 409-30. PMID 22292480 DOI: 10.1111/j.1467-789X.2011.00979.x |
0.318 |
|
2012 |
Luo Y, Li X, Chen T, Wang Y, Zheng W. Synthesis of a novel thiophene derivative that induces cancer cell apoptosis through modulation of AKT and MAPK pathways Medchemcomm. 3: 1143. DOI: 10.1039/C2Md20041D |
0.387 |
|
2012 |
Wu H, Li X, Liu W, Chen T, Li Y, Zheng W, Man CW, Wong M, Wong K. Surface decoration of selenium nanoparticles by mushroom polysaccharides–protein complexes to achieve enhanced cellular uptake and antiproliferative activity Journal of Materials Chemistry. 22: 9602. DOI: 10.1039/C2Jm16828F |
0.379 |
|
2011 |
Luo Y, Li X, Huang X, Wong YS, Chen T, Zhang Y, Zheng W. 1,4-Diselenophene-1,4-diketone triggers caspase-dependent apoptosis in human melanoma A375 cells through induction of mitochondrial dysfunction. Chemical & Pharmaceutical Bulletin. 59: 1227-32. PMID 21963631 DOI: 10.1248/Cpb.59.1227 |
0.414 |
|
2011 |
Li Y, Li X, Wong YS, Chen T, Zhang H, Liu C, Zheng W. The reversal of cisplatin-induced nephrotoxicity by selenium nanoparticles functionalized with 11-mercapto-1-undecanol by inhibition of ROS-mediated apoptosis. Biomaterials. 32: 9068-76. PMID 21864903 DOI: 10.1016/J.Biomaterials.2011.08.001 |
0.393 |
|
2011 |
Li XL, Chen T, Wong YS, Xu G, Fan RR, Zhao HL, Chan JC. Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin. The International Journal of Biochemistry & Cell Biology. 43: 525-34. PMID 21163363 DOI: 10.1016/J.Biocel.2010.12.008 |
0.679 |
|
2010 |
Fan R, Li X, Gu X, Chan JC, Xu G. Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis. Diabetes, Obesity & Metabolism. 12: 815-24. PMID 20649634 DOI: 10.1111/J.1463-1326.2010.01238.X |
0.676 |
|
2009 |
Li X, Hu D, Dang Y, Chen H, Roco MC, Larson CA, Chan J. Nano Mapper: an Internet knowledge mapping system for nanotechnology development. Journal of Nanoparticle Research : An Interdisciplinary Forum For Nanoscale Science and Technology. 11: 529-552. PMID 21170121 DOI: 10.1007/S11051-008-9491-Z |
0.315 |
|
2009 |
Li XL, Xu G, Chen T, Wong YS, Zhao HL, Fan RR, Gu XM, Tong PC, Chan JC. Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways. The International Journal of Biochemistry & Cell Biology. 41: 1526-35. PMID 19166964 DOI: 10.1016/J.Biocel.2009.01.002 |
0.693 |
|
2005 |
Chan JL, Moschos SJ, Bullen J, Heist K, Li X, Kim YB, Kahn BB, Mantzoros CS. Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and regulates soluble tumor necrosis factor-alpha receptor levels in humans with relative leptin deficiency. The Journal of Clinical Endocrinology and Metabolism. 90: 1625-31. PMID 15613409 DOI: 10.1210/Jc.2004-1823 |
0.375 |
|
2002 |
Chen CP, Li XX, Zhang LR, Min JM, Chan JY, Fung KP, Wang SQ, Zhang LH. Synthesis of antisense oligonucleotide-peptide conjugate targeting to GLUT-1 in HepG-2 and MCF-7 Cells. Bioconjugate Chemistry. 13: 525-9. PMID 12009942 DOI: 10.1021/Bc015540F |
0.397 |
|
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