Deepak Srivastava - Publications

Affiliations: 
Gladstone Institute University of California, San Francisco, San Francisco, CA 

197 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zholudeva LV, Fortino T, Agrawal A, Vila OF, Williams M, McDevitt T, Lane MA, Srivastava D. Human spinal interneurons repair the injured spinal cord through synaptic integration. Biorxiv : the Preprint Server For Biology. PMID 38260390 DOI: 10.1101/2024.01.11.575264  0.486
2023 Maven BEJ, Gifford CA, Weilert M, Gonzalez-Teran B, Hüttenhain R, Pelonero A, Ivey KN, Samse-Knapp K, Kwong W, Gordon D, McGregor M, Nishino T, Okorie E, Rossman S, Costa MW, ... ... Srivastava D, et al. The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5. Stem Cell Reports. PMID 37863045 DOI: 10.1016/j.stemcr.2023.09.014  0.348
2023 Young Jang M, Patel PN, Pereira AC, Willcox JAL, Haghighi A, Tai AC, Ito K, Morton SU, Gorham JM, McKean DM, DePalma SR, Bernstein D, Brueckner M, Chung WK, Giardini A, ... ... Srivastava D, et al. Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease. Circulation. Genomic and Precision Medicine. e003924. PMID 37165897 DOI: 10.1161/CIRCGEN.122.003924  0.581
2023 Krup AL, Winchester SAB, Ranade SS, Agrawal A, Devine WP, Sinha T, Choudhary K, Dominguez MH, Thomas R, Black BL, Srivastava D, Bruneau BG. A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors. Development (Cambridge, England). PMID 36994838 DOI: 10.1242/dev.201229  0.658
2023 Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Lee CY, Sadagopan N, Huang Y, Pelonero A, Auclair K, Zhu A, Gonzalez Teran B, Flanigan W, Kim CK, Lumbao-Conradson K, ... ... Srivastava D, et al. Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis. Biorxiv : the Preprint Server For Biology. PMID 36711864 DOI: 10.1101/2023.01.06.522937  0.314
2023 Bock-Marquette I, Maar K, Maar S, Lippai B, Faskerti G, Gallyas F, Olson EN, Srivastava D. Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. International Immunopharmacology. 116: 109741. PMID 36709593 DOI: 10.1016/j.intimp.2023.109741  0.454
2022 Smith GA, Padmanabhan A, Lau BH, Pampana A, Li L, Lee CY, Pelonero A, Nishino T, Sadagopan N, Xia VQ, Jain R, Natarajan P, Wu RS, Black BL, Srivastava D, et al. Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor. Science Translational Medicine. 14: eabj8670. PMID 36103516 DOI: 10.1126/scitranslmed.abj8670  0.594
2022 Zhu L, Choudhary K, Gonzalez-Teran B, Ang YS, Thomas R, Stone NR, Liu L, Zhou P, Zhu C, Ruan H, Huang Y, Jin S, Pelonero A, Koback F, Padmanabhan A, ... ... Srivastava D, et al. Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors. Circulation. CIRCULATIONAHA121057. PMID 35938400 DOI: 10.1161/CIRCULATIONAHA.121.057620  0.661
2022 Srivastava D. Cellular cross-talk in heart repair. Science (New York, N.Y.). 376: 1271-1272. PMID 35709257 DOI: 10.1126/science.adc8698  0.304
2022 Willcox JAL, Geiger JT, Morton SU, McKean D, Quiat D, Gorham JM, Tai AC, DePalma S, Bernstein D, Brueckner M, Chung WK, Giardini A, Goldmuntz E, Kaltman JR, Kim R, ... ... Srivastava D, et al. Neither cardiac mitochondrial DNA variation or copy number contribute to congenital heart disease risk. American Journal of Human Genetics. PMID 35397206 DOI: 10.1016/j.ajhg.2022.03.011  0.575
2022 Gonzalez-Teran B, Pittman M, Felix F, Thomas R, Richmond-Buccola D, Hüttenhain R, Choudhary K, Moroni E, Costa MW, Huang Y, Padmanabhan A, Alexanian M, Lee CY, Maven BEJ, Samse-Knapp K, ... ... Srivastava D, et al. Transcription factor protein interactomes reveal genetic determinants in heart disease. Cell. PMID 35182466 DOI: 10.1016/j.cell.2022.01.021  0.753
2021 Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, ... ... Srivastava D, et al. A transcriptional switch governs fibroblast activation in heart disease. Nature. PMID 34163071 DOI: 10.1038/s41586-021-03674-1  0.326
2021 Srivastava D, McDevitt TC. Mouse gastruloids take heart. Nature Reviews. Cardiology. PMID 33414560 DOI: 10.1038/s41569-020-00501-4  0.598
2020 Padmanabhan A, Alexanian M, Linares-Saldana R, González-Terán B, Andreoletti G, Huang Y, Connolly AJ, Kim W, Hsu A, Duan Q, Winchester SAB, Felix F, Perez-Bermejo JA, Wang Q, Li L, ... ... Srivastava D, et al. BRD4 Interacts with GATA4 to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes. Circulation. PMID 33094644 DOI: 10.1161/CIRCULATIONAHA.120.047753  0.347
2020 Morton SU, Shimamura A, Newburger PE, Opotowsky AR, Quiat D, Pereira AC, Jin SC, Gurvitz M, Brueckner M, Chung WK, Shen Y, Bernstein D, Gelb BD, Giardini A, Goldmuntz E, ... ... Srivastava D, et al. Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease. Jama Cardiology. PMID 33084842 DOI: 10.1001/jamacardio.2020.4947  0.552
2020 Sharma A, Wasson LK, Willcox JA, Morton SU, Gorham JM, DeLaughter DM, Neyazi M, Schmid M, Agarwal R, Jang MY, Toepfer CN, Ward T, Kim Y, Pereira AC, DePalma SR, ... ... Srivastava D, et al. utations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm. Elife. 9. PMID 33054971 DOI: 10.7554/eLife.53278  0.671
2020 Boskovski MT, Homsy J, Nathan M, Sleeper LA, Morton S, Manheimer KB, Tai A, Gorham J, Lewis M, Swartz M, Alfieris GM, Bacha EA, Karimi M, Meyer D, Nguyen K, ... ... Srivastava D, et al. De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease. Circulation. Genomic and Precision Medicine. 13: e002836. PMID 32812804 DOI: 10.1161/CIRCGEN.119.002836  0.609
2020 Richter F, Morton SU, Kim SW, Kitaygorodsky A, Wasson LK, Chen KM, Zhou J, Qi H, Patel N, DePalma SR, Parfenov M, Homsy J, Gorham JM, Manheimer KB, Velinder M, ... ... Srivastava D, et al. Genomic analyses implicate noncoding de novo variants in congenital heart disease. Nature Genetics. PMID 32601476 DOI: 10.1038/S41588-020-0652-Z  0.619
2020 Funato N, Srivastava D, Shibata S, Yanagisawa H. TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. Journal of Dental Research. 22034520925080. PMID 32442036 DOI: 10.1177/0022034520925080  0.395
2020 Edwards JJ, Rouillard AD, Fernandez NF, Wang Z, Lachmann A, Shankaran SS, Bisgrove BW, Demarest B, Turan N, Srivastava D, Bernstein D, Deanfield J, Giardini A, Porter G, Kim R, et al. Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects. Jacc. Basic to Translational Science. 5: 376-386. PMID 32368696 DOI: 10.1016/J.Jacbts.2020.01.012  0.406
2020 Hsieh A, Morton SU, Willcox JAL, Gorham JM, Tai AC, Qi H, DePalma S, McKean D, Griffin E, Manheimer KB, Bernstein D, Kim RW, Newburger JW, Porter GA, Srivastava D, et al. EM-mosaic detects mosaic point mutations that contribute to congenital heart disease. Genome Medicine. 12: 42. PMID 32349777 DOI: 10.1186/S13073-020-00738-1  0.635
2019 Stratton MS, Bagchi RA, Felisbino MB, Hirsch RA, Smith HE, Riching AS, Enyart BY, Koch KA, Cavasin MA, Alexanian M, Song K, Qi J, Lemieux ME, Srivastava D, Lam MP, et al. Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation. Circulation Research. PMID 31409188 DOI: 10.1161/Circresaha.119.315125  0.41
2019 de Soysa TY, Ranade SS, Okawa S, Ravichandran S, Huang Y, Salunga HT, Schricker A, Del Sol A, Gifford CA, Srivastava D. Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects. Nature. PMID 31341279 DOI: 10.1038/S41586-019-1414-X  0.468
2019 Stone NR, Gifford CA, Thomas R, Pratt KJB, Samse-Knapp K, Mohamed TMA, Radzinsky EM, Schricker A, Ye L, Yu P, van Bemmel JG, Ivey KN, Pollard KS, Srivastava D. Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming. Cell Stem Cell. 25: 87-102.e9. PMID 31271750 DOI: 10.1016/J.Stem.2019.06.012  0.408
2019 Gifford CA, Ranade SS, Samarakoon R, Salunga HT, de Soysa TY, Huang Y, Zhou P, Elfenbein A, Wyman SK, Bui YK, Cordes Metzler KR, Ursell P, Ivey KN, Srivastava D. Oligogenic inheritance of a human heart disease involving a genetic modifier. Science (New York, N.Y.). 364: 865-870. PMID 31147515 DOI: 10.1126/Science.Aat5056  0.744
2019 Samal E, Evangelista M, Galang G, Srivastava D, Zhao Y, Vedantham V. Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System. Frontiers in Physiology. 10: 235. PMID 30936836 DOI: 10.3389/Fphys.2019.00235  0.436
2019 Gonzalez Teran B, Pittman M, Richmond-Buccola D, Samse K, Cole B, Huttenhain R, McGregor M, Krogan N, Pollard K, Srivastava D. Abstract 197: Transcription Factor Interactome in Human iPS-derived Cardiac Progenitors is Enriched for Proteins Associated With Congenital Heart Disease Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.197  0.439
2019 Duarte R, Powell T, Anderson G, Lee S, Breen G, Nixon D, Murray R, Bray N, Srivastava D. EXPRESSION SIGNATURE ASSOCIATED WITH CORTICAL MATURATION AND ITS POTENTIAL ASSOCIATION WITH GENETIC RISK FOR SCHIZOPHRENIA European Neuropsychopharmacology. 29: S987-S988. DOI: 10.1016/J.Euroneuro.2017.08.367  0.307
2018 Mohamed TMA, Ang YS, Radzinsky E, Zhou P, Huang Y, Elfenbein A, Foley A, Magnitsky S, Srivastava D. Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration. Cell. PMID 29502971 DOI: 10.1016/J.Cell.2018.02.014  0.379
2017 Jin SC, Homsy J, Zaidi S, Lu Q, Morton S, DePalma SR, Zeng X, Qi H, Chang W, Sierant MC, Hung WC, Haider S, Zhang J, Knight J, Bjornson RD, ... ... Srivastava D, et al. Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands. Nature Genetics. PMID 28991257 DOI: 10.1038/Ng.3970  0.64
2017 Judge LM, Perez-Bermejo JA, Truong A, Ribeiro AJ, Yoo JC, Jensen CL, Mandegar MA, Huebsch N, Kaake RM, So PL, Srivastava D, Pruitt BL, Krogan NJ, Conklin BR. A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress. Jci Insight. 2. PMID 28724793 DOI: 10.1172/Jci.Insight.94623  0.434
2017 Duan Q, McMahon S, Anand P, Shah H, Thomas S, Salunga HT, Huang Y, Zhang R, Sahadevan A, Lemieux ME, Brown JD, Srivastava D, Bradner JE, McKinsey TA, Haldar SM. BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure. Science Translational Medicine. 9. PMID 28515341 DOI: 10.1126/Scitranslmed.Aah5084  0.421
2017 Ribeiro AJ, Schwab O, Mandegar MA, Ang YS, Conklin BR, Srivastava D, Pruitt BL. Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes. Circulation Research. PMID 28400398 DOI: 10.1161/Circresaha.116.310363  0.437
2017 Theodoris CV, Mourkioti F, Huang Y, Ranade SS, Liu L, Blau HM, Srivastava D. Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency. The Journal of Clinical Investigation. PMID 28346225 DOI: 10.1172/Jci90338  0.377
2017 Zhu JY, Heidersbach A, Kathiriya IS, Garay BI, Ivey KN, Srivastava D, Han Z, King IN. The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1. Development (Cambridge, England). 144: 866-875. PMID 28246214 DOI: 10.1242/Dev.140368  0.77
2017 Zhu J, Heidersbach A, Kathiriya IS, Garay BI, Ivey KN, Srivastava D, Han Z, King IN. The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1 Journal of Cell Science. 130. DOI: 10.1242/Jcs.203083  0.706
2016 Ang YS, Rivas RN, Ribeiro AJ, Srivas R, Rivera J, Stone NR, Pratt K, Mohamed TM, Fu JD, Spencer CI, Tippens ND, Li M, Narasimha A, Radzinsky E, Moon-Grady AJ, ... Srivastava D, et al. Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell. 167: 1734-1749.e22. PMID 27984724 DOI: 10.1016/J.Cell.2016.11.033  0.425
2016 Mohamed TM, Stone NR, Berry EC, Radzinsky E, Huang Y, Pratt K, Ang YS, Yu P, Wang H, Tang S, Magnitsky S, Ding S, Ivey KN, Srivastava D. Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming. Circulation. PMID 27834668 DOI: 10.1161/Circulationaha.116.024692  0.431
2016 Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, ... Srivastava D, et al. The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nature Medicine. PMID 27618650 DOI: 10.1038/Nm.4179  0.453
2016 Srivastava D, DeWitt N. In Vivo Cellular Reprogramming: The Next Generation. Cell. 166: 1386-1396. PMID 27610565 DOI: 10.1016/J.Cell.2016.08.055  0.345
2016 Barruet E, Morales BM, Lwin W, White MP, Theodoris CV, Kim H, Urrutia A, Wong SA, Srivastava D, Hsiao EC. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling. Stem Cell Research & Therapy. 7: 115. PMID 27530160 DOI: 10.1186/S13287-016-0372-6  0.32
2016 Sia J, Yu P, Srivastava D, Li S. Effect of biophysical cues on reprogramming to cardiomyocytes. Biomaterials. 103: 1-11. PMID 27376554 DOI: 10.1016/J.Biomaterials.2016.06.034  0.324
2016 Haldar SM, Srivastava D. Sarcomeres and Cardiac Growth: Tension in the Relationship. Trends in Molecular Medicine. PMID 27237981 DOI: 10.1016/J.Molmed.2016.05.001  0.38
2016 Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, B Fox C, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, et al. Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Scientific Reports. 6: 24726. PMID 27095412 DOI: 10.1038/Srep24726  0.34
2016 Zhang Y, Cao N, Huang Y, Spencer CI, Fu JD, Yu C, Liu K, Nie B, Xu T, Li K, Xu S, Bruneau BG, Srivastava D, Ding S. Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts. Cell Stem Cell. 18: 368-381. PMID 26942852 DOI: 10.1016/J.Stem.2016.02.001  0.453
2016 Gifford CA, Srivastava D. Heart disease modelling adds a Notch to its belt. Nature Cell Biology. 18: 3-5. PMID 26693916 DOI: 10.1038/Ncb3294  0.43
2016 Ribeiro AJ, Ang Y, Wilson RE, Rivas RN, Srivastava D, Pruitt BL. A Tuned Tension Regulates the Contractility of Cardiomyocytes Differentiated from Induced Pluripotent Stem Cells Biophysical Journal. 110: 294a. DOI: 10.1016/J.Bpj.2015.11.1587  0.359
2015 Srivastava D, Yu P. Recent advances in direct cardiac reprogramming. Current Opinion in Genetics & Development. 34: 77-81. PMID 26454285 DOI: 10.1016/J.Gde.2015.09.004  0.436
2015 Kime C, Rand TA, Ivey KN, Srivastava D, Yamanaka S, Tomoda K. Practical Integration-Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. 87: 21.2.1-21.2.21. PMID 26439714 DOI: 10.1002/0471142905.Hg2102S87  0.308
2015 Ribeiro AJ, Ang YS, Fu JD, Rivas RN, Mohamed TM, Higgs GC, Srivastava D, Pruitt BL. Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness. Proceedings of the National Academy of Sciences of the United States of America. 112: 12705-10. PMID 26417073 DOI: 10.1073/Pnas.1508073112  0.343
2015 Ivey KN, Srivastava D. microRNAs as Developmental Regulators Cold Spring Harbor Perspectives in Biology. 7: a008144. PMID 26134312 DOI: 10.1101/Cshperspect.A008144  0.312
2015 White MP, Theodoris CV, Liu L, Collins WJ, Blue KW, Lee JH, Meng X, Robbins RC, Ivey KN, Srivastava D. NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium. Journal of Molecular and Cellular Cardiology. 84: 13-23. PMID 25871831 DOI: 10.1016/J.Yjmcc.2015.04.006  0.339
2015 Rasmussen TL, Ma Y, Park CY, Harriss J, Pierce SA, Dekker JD, Valenzuela N, Srivastava D, Schwartz RJ, Stewart MD, Tucker HO. Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses. Plos One. 10: e0121765. PMID 25803368 DOI: 10.1371/Journal.Pone.0121765  0.431
2015 Theodoris CV, Li M, White MP, Liu L, He D, Pollard KS, Bruneau BG, Srivastava D. Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency. Cell. 160: 1072-86. PMID 25768904 DOI: 10.1016/J.Cell.2015.02.035  0.355
2015 Fu JD, Srivastava D. Direct reprogramming of fibroblasts into cardiomyocytes for cardiac regenerative medicine. Circulation Journal : Official Journal of the Japanese Circulation Society. 79: 245-54. PMID 25744738 DOI: 10.1253/Circj.Cj-14-1372  0.456
2015 Vedantham V, Galang G, Evangelista M, Deo RC, Srivastava D. RNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells. Circulation Research. 116: 797-803. PMID 25623957 DOI: 10.1161/Circresaha.116.305913  0.374
2015 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H. Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Human Molecular Genetics. 24: 424-35. PMID 25209980 DOI: 10.1093/Hmg/Ddu458  0.33
2014 Ang YS, Srivastava D. Oxygen: double-edged sword in cardiac function and repair. Circulation Research. 115: 824-5. PMID 25342770 DOI: 10.1161/Circresaha.114.305322  0.418
2014 Hua LL, Vedantham V, Barnes RM, Hu J, Robinson AS, Bressan M, Srivastava D, Black BL. Specification of the mouse cardiac conduction system in the absence of Endothelin signaling. Developmental Biology. 393: 245-54. PMID 25050930 DOI: 10.1016/J.Ydbio.2014.07.008  0.68
2014 Hu H, Roach JC, Coon H, Guthery SL, Voelkerding KV, Margraf RL, Durtschi JD, Tavtigian SV, Shankaracharya, Wu W, Scheet P, Wang S, Xing J, Glusman G, Hubley R, ... ... Srivastava D, et al. A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data. Nature Biotechnology. 32: 663-9. PMID 24837662 DOI: 10.1038/Nbt.2895  0.586
2014 King IN, Yartseva V, Salas D, Kumar A, Heidersbach A, Ando DM, Stallings NR, Elliott JL, Srivastava D, Ivey KN. The RNA-binding protein TDP-43 selectively disrupts microRNA-1/206 incorporation into the RNA-induced silencing complex. The Journal of Biological Chemistry. 289: 14263-71. PMID 24719334 DOI: 10.1074/Jbc.M114.561902  0.748
2014 Wang H, Cao N, Spencer CI, Nie B, Ma T, Xu T, Zhang Y, Wang X, Srivastava D, Ding S. Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. Cell Reports. 6: 951-60. PMID 24561253 DOI: 10.1016/J.Celrep.2014.01.038  0.444
2014 Bruneau BG, Srivastava D. Congenital heart disease: entering a new era of human genetics. Circulation Research. 114: 598-9. PMID 24526674 DOI: 10.1161/Circresaha.113.303060  0.403
2014 Worringer KA, Rand TA, Hayashi Y, Sami S, Takahashi K, Tanabe K, Narita M, Srivastava D, Yamanaka S. The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes. Cell Stem Cell. 14: 40-52. PMID 24239284 DOI: 10.1016/J.Stem.2013.11.001  0.38
2013 Fu JD, Stone NR, Liu L, Spencer CI, Qian L, Hayashi Y, Delgado-Olguin P, Ding S, Bruneau BG, Srivastava D. Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state. Stem Cell Reports. 1: 235-47. PMID 24319660 DOI: 10.1016/J.Stemcr.2013.07.005  0.413
2013 Heidersbach A, Saxby C, Carver-Moore K, Huang Y, Ang YS, de Jong PJ, Ivey KN, Srivastava D. microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart. Elife. 2: e01323. PMID 24252873 DOI: 10.7554/Elife.01323  0.768
2013 Qian L, Srivastava D. Direct cardiac reprogramming: from developmental biology to cardiac regeneration. Circulation Research. 113: 915-21. PMID 24030021 DOI: 10.1161/Circresaha.112.300625  0.475
2013 Srivastava D, Berry EC. Cardiac reprogramming: from mouse toward man. Current Opinion in Genetics & Development. 23: 574-8. PMID 23993230 DOI: 10.1016/J.Gde.2013.07.007  0.425
2013 Qian L, Berry EC, Fu JD, Ieda M, Srivastava D. Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro. Nature Protocols. 8: 1204-15. PMID 23722259 DOI: 10.1038/Nprot.2013.067  0.427
2013 Cheng P, Andersen P, Hassel D, Kaynak BL, Limphong P, Juergensen L, Kwon C, Srivastava D. Fibronectin mediates mesendodermal cell fate decisions. Development (Cambridge, England). 140: 2587-96. PMID 23715551 DOI: 10.1242/Dev.089052  0.342
2013 Srivastava D, Heidersbach AJ. Small solutions to big problems: microRNAs for cardiac regeneration. Circulation Research. 112: 1412-4. PMID 23704215 DOI: 10.1161/Circresaha.113.301409  0.786
2013 Spindler MJ, Burmeister BT, Huang Y, Hsiao EC, Salomonis N, Scott MJ, Srivastava D, Carnegie GK, Conklin BR. AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy. Plos One. 8: e62705. PMID 23658642 DOI: 10.1371/Journal.Pone.0062705  0.393
2013 Srivastava D, Cordes Metzler KR. Fending for a Braveheart. The Embo Journal. 32: 1211-3. PMID 23524853 DOI: 10.1038/Emboj.2013.71  0.455
2013 Limphong P, Zhang H, Christians E, Liu Q, Riedel M, Ivey K, Cheng P, Mitzelfelt K, Taylor G, Winge D, Srivastava D, Benjamin I. Modeling human protein aggregation cardiomyopathy using murine induced pluripotent stem cells. Stem Cells Translational Medicine. 2: 161-6. PMID 23430692 DOI: 10.5966/Sctm.2012-0073  0.396
2013 Vedantham V, Evangelista M, Huang Y, Srivastava D. Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning. Developmental Biology. 373: 149-62. PMID 23085412 DOI: 10.1016/J.Ydbio.2012.10.017  0.422
2013 White MP, Rufaihah AJ, Liu L, Ghebremariam YT, Ivey KN, Cooke JP, Srivastava D. Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem Cells (Dayton, Ohio). 31: 92-103. PMID 23079999 DOI: 10.1002/Stem.1267  0.337
2013 Heidersbach A, Saxby C, Carver-Moore K, Huang Y, Ang Y, Jong PJd, Ivey KN, Srivastava D. Author response: microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart Elife. DOI: 10.7554/Elife.01323.038  0.766
2013 Cheng P, Andersen P, Hassel D, Kaynak BL, Limphong P, Juergensen L, Kwon C, Srivastava D. Fibronectin mediates mesendodermal cell fate decisions Journal of Cell Science. 126: 2587-2596. DOI: 10.1242/Jcs.136309  0.342
2012 Srivastava D, Ieda M, Fu J, Qian L. Cardiac repair with thymosin β4 and cardiac reprogramming factors. Annals of the New York Academy of Sciences. 1270: 66-72. PMID 23050819 DOI: 10.1111/J.1749-6632.2012.06696.X  0.445
2012 Farina NH, Hausburg M, Betta ND, Pulliam C, Srivastava D, Cornelison D, Olwin BB. A role for RNA post-transcriptional regulation in satellite cell activation. Skeletal Muscle. 2: 21. PMID 23046558 DOI: 10.1186/2044-5040-2-21  0.379
2012 Wamstad JA, Alexander JM, Truty RM, Shrikumar A, Li F, Eilertson KE, Ding H, Wylie JN, Pico AR, Capra JA, Erwin G, Kattman SJ, Keller GM, Srivastava D, Levine SS, et al. Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage. Cell. 151: 206-20. PMID 22981692 DOI: 10.1016/J.Cell.2012.07.035  0.463
2012 Hassel D, Cheng P, White MP, Ivey KN, Kroll J, Augustin HG, Katus HA, Stainier DY, Srivastava D. MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling. Circulation Research. 111: 1421-33. PMID 22955733 DOI: 10.1161/Circresaha.112.279711  0.359
2012 Srivastava D, Ieda M. Critical factors for cardiac reprogramming Circulation Research. 111: 5-8. PMID 22723217 DOI: 10.1161/Circresaha.112.271452  0.36
2012 Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V. Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. Plos Genetics. 8: e1002690. PMID 22589735 DOI: 10.1371/Journal.Pgen.1002690  0.641
2012 Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, Liu L, Conway SJ, Fu JD, Srivastava D. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature. 485: 593-8. PMID 22522929 DOI: 10.1038/Nature11044  0.342
2012 Bernstein HS, Srivastava D. Stem cell therapy for cardiac disease Pediatric Research. 71: 491-499. PMID 22430385 DOI: 10.1038/Pr.2011.61  0.438
2012 Kathiresan S, Srivastava D. Genetics of human cardiovascular disease. Cell. 148: 1242-57. PMID 22424232 DOI: 10.1016/J.Cell.2012.03.001  0.354
2012 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H. Tbx1 regulates oral epithelial adhesion and palatal development. Human Molecular Genetics. 21: 2524-37. PMID 22371266 DOI: 10.1093/Hmg/Dds071  0.39
2012 Srivastava D, Olson EN. Knowing in your heart what's right. Trends in Cell Biology. 7: 447-53. PMID 17709004 DOI: 10.1016/S0962-8924(97)01150-1  0.562
2011 Roach JC, Glusman G, Hubley R, Montsaroff SZ, Holloway AK, Mauldin DE, Srivastava D, Garg V, Pollard KS, Galas DJ, Hood L, Smit AF. Chromosomal haplotypes by genetic phasing of human families. American Journal of Human Genetics. 89: 382-97. PMID 21855840 DOI: 10.1016/J.Ajhg.2011.07.023  0.562
2011 AlRais F, Feldstein VA, Srivastava D, Gosnell K, Moon-Grady AJ. Monochorionic twins discordant for congenital heart disease: a referral center's experience and possible pathophysiologic mechanisms Prenatal Diagnosis. 31: 978-984. PMID 21744365 DOI: 10.1002/Pd.2819  0.425
2011 Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, ... Srivastava D, et al. Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. The Journal of Cell Biology. 193: 1181-96. PMID 21690310 DOI: 10.1083/Jcb.201006114  0.633
2011 Shieh JT, Huang Y, Gilmore J, Srivastava D. Elevated miR-499 levels blunt the cardiac stress response. Plos One. 6: e19481. PMID 21573063 DOI: 10.1371/Journal.Pone.0019481  0.473
2011 King IN, Qian L, Liang J, Huang Y, Shieh JT, Kwon C, Srivastava D. A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity. Developmental Cell. 20: 497-510. PMID 21497762 DOI: 10.1016/J.Devcel.2011.03.010  0.481
2011 Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S. A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development (Cambridge, England). 138: 1409-19. PMID 21385766 DOI: 10.1242/Dev.060046  0.413
2011 Qian L, Van Laake LW, Huang Y, Liu S, Wendland MF, Srivastava D. miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. The Journal of Experimental Medicine. 208: 549-60. PMID 21383058 DOI: 10.1084/Jem.20101547  0.309
2011 Yu S, Crawford D, Tsuchihashi T, Behrens TW, Srivastava D. The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 384-93. PMID 21246655 DOI: 10.1002/Dvdy.22549  0.375
2011 Tsuchihashi T, Maeda J, Shin CH, Ivey KN, Black BL, Olson EN, Yamagishi H, Srivastava D. Hand2 function in second heart field progenitors is essential for cardiogenesis. Developmental Biology. 351: 62-9. PMID 21185281 DOI: 10.1016/J.Ydbio.2010.12.023  0.74
2010 Sheehy NT, Cordes KR, White MP, Ivey KN, Srivastava D. The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch. Development (Cambridge, England). 137: 4307-16. PMID 21098571 DOI: 10.1242/Dev.052647  0.79
2010 Park CY, Pierce SA, von Drehle M, Ivey KN, Morgan JA, Blau HM, Srivastava D. skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. Proceedings of the National Academy of Sciences of the United States of America. 107: 20750-5. PMID 21071677 DOI: 10.1073/Pnas.1013493107  0.428
2010 Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell. 142: 375-86. PMID 20691899 DOI: 10.1016/J.Cell.2010.07.002  0.465
2010 Ivey KN, Srivastava D. MicroRNAs as regulators of differentiation and cell fate decisions. Cell Stem Cell. 7: 36-41. PMID 20621048 DOI: 10.1016/J.Stem.2010.06.012  0.367
2010 Maitra M, Koenig SN, Srivastava D, Garg V. Identification of GATA6 sequence variants in patients with congenital heart defects. Pediatric Research. 68: 281-5. PMID 20581743 DOI: 10.1203/PDR.0b013e3181ed17e4  0.69
2010 van Laake LW, Qian L, Cheng P, Huang Y, Hsiao EC, Conklin BR, Srivastava D. Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. Circulation Research. 107: 340-7. PMID 20558827 DOI: 10.1161/Circresaha.109.215434  0.408
2010 Shrivastava S, Srivastava D, Olson EN, Dimaio JM, Bock-Marquette I. Thymosin β4 and cardiac repair Annals of the New York Academy of Sciences. 1194: 87-96. PMID 20536454 DOI: 10.1111/J.1749-6632.2010.05468.X  0.545
2010 Qian L, Srivastava D. Monkeying around with cardiac progenitors: hope for the future. The Journal of Clinical Investigation. 120: 1034-6. PMID 20335651 DOI: 10.1172/Jci42643  0.427
2010 Cordes KR, Srivastava D, Ivey KN. MicroRNAs in cardiac development. Pediatric Cardiology. 31: 349-56. PMID 20140609 DOI: 10.1007/S00246-010-9639-3  0.393
2010 Woo S, Fish JE, Wythe JD, Bruneau BB, Stainier DY, Srivastava D. A novel Slit–Robo–miR-218 signaling axis regulates VEGF-mediated heart tube formation in zebrafish Developmental Biology. 344: 433. DOI: 10.1016/J.Ydbio.2010.05.094  0.387
2009 Nigam V, Srivastava D. Notch1 represses osteogenic pathways in aortic valve cells. Journal of Molecular and Cellular Cardiology. 47: 828-34. PMID 19695258 DOI: 10.1016/J.Yjmcc.2009.08.008  0.347
2009 Kwon C, Qian L, Cheng P, Nigam V, Arnold J, Srivastava D. A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate. Nature Cell Biology. 11: 951-7. PMID 19620969 DOI: 10.1038/Ncb1906  0.426
2009 Shieh JT, Srivastava D. Heart malformation: what are the chances it could happen again? Circulation. 120: 269-71. PMID 19597046 DOI: 10.1161/Circulationaha.109.878637  0.379
2009 Cordes KR, Sheehy NT, White MP, Berry EC, Morton SU, Muth AN, Lee TH, Miano JM, Ivey KN, Srivastava D. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature. 460: 705-10. PMID 19578358 DOI: 10.1038/Nature08195  0.765
2009 Bock-Marquette I, Shrivastava S, Pipes GC, Thatcher JE, Blystone A, Shelton JM, Galindo CL, Melegh B, Srivastava D, Olson EN, DiMaio JM. Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. Journal of Molecular and Cellular Cardiology. 46: 728-38. PMID 19358334 DOI: 10.1016/J.Yjmcc.2009.01.017  0.508
2009 Cordes KR, Srivastava D. MicroRNA regulation of cardiovascular development. Circulation Research. 104: 724-32. PMID 19325160 DOI: 10.1161/Circresaha.108.192872  0.398
2009 Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell. 4: 198-9; author reply . PMID 19265656 DOI: 10.1016/J.Stem.2009.02.010  0.308
2009 Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D. Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Developmental Cell. 16: 233-44. PMID 19217425 DOI: 10.1016/J.Devcel.2008.12.007  0.453
2009 Fish JE, Srivastava D. MicroRNAs: opening a new vein in angiogenesis research. Science Signaling. 2. PMID 19126861 DOI: 10.1126/Scisignal.252Pe1  0.347
2009 Maitra M, Schluterman MK, Nichols HA, Richardson JA, Lo CW, Srivastava D, Garg V. Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Developmental Biology. 326: 368-77. PMID 19084512 DOI: 10.1016/J.Ydbio.2008.11.004  0.698
2008 Kwon C, Cordes KR, Srivastava D. Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis. Cell Cycle (Georgetown, Tex.). 7: 3815-8. PMID 19066459 DOI: 10.4161/Cc.7.24.7189  0.407
2008 Morton SU, Scherz PJ, Cordes KR, Ivey KN, Stainier DY, Srivastava D. microRNA-138 modulates cardiac patterning during embryonic development. Proceedings of the National Academy of Sciences of the United States of America. 105: 17830-5. PMID 19004786 DOI: 10.1073/Pnas.0804673105  0.666
2008 Niu Z, Iyer D, Conway SJ, Martin JF, Ivey K, Srivastava D, Nordheim A, Schwartz RJ. Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart Proceedings of the National Academy of Sciences of the United States of America. 105: 17824-17829. PMID 19004760 DOI: 10.1073/Pnas.0805491105  0.628
2008 Ransom JF, King IN, Garg V, Srivastava D. A rare human sequence variant reveals myocardin autoinhibition. The Journal of Biological Chemistry. 283: 35845-52. PMID 18852265 DOI: 10.1074/Jbc.M805909200  0.671
2008 Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D. miR-126 regulates angiogenic signaling and vascular integrity. Developmental Cell. 15: 272-84. PMID 18694566 DOI: 10.1016/J.Devcel.2008.07.008  0.637
2008 Ivey KN, Sutcliffe D, Richardson J, Clyman RI, Garcia JA, Srivastava D. Transcriptional regulation during development of the ductus arteriosus. Circulation Research. 103: 388-95. PMID 18635823 DOI: 10.1161/Circresaha.108.180661  0.396
2008 Saxena A, Fish JE, White MD, Yu S, Smyth JW, Shaw RM, DiMaio JM, Srivastava D. Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation. 117: 2224-31. PMID 18427137 DOI: 10.1161/Circulationaha.107.694992  0.68
2008 Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell. 2: 219-29. PMID 18371447 DOI: 10.1016/J.Stem.2008.01.016  0.429
2007 Jia H, King IN, Chopra SS, Wan H, Ni TT, Jiang C, Guan X, Wells S, Srivastava D, Zhong TP. Vertebrate heart growth is regulated by functional antagonism between Gridlock and Gata5. Proceedings of the National Academy of Sciences of the United States of America. 104: 14008-13. PMID 17715064 DOI: 10.1073/Pnas.0702240104  0.465
2007 Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu WT. Spectrum of heart disease associated with murine and human GATA4 mutation. Journal of Molecular and Cellular Cardiology. 43: 677-85. PMID 17643447 DOI: 10.1016/J.Yjmcc.2007.06.004  0.645
2007 Srivastava D, Saxena A, Michael Dimaio J, Bock-Marquette I. Thymosin beta4 is cardioprotective after myocardial infarction. Annals of the New York Academy of Sciences. 1112: 161-70. PMID 17600280 DOI: 10.1196/Annals.1415.048  0.696
2007 Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D. Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proceedings of the National Academy of Sciences of the United States of America. 104: 10894-9. PMID 17576928 DOI: 10.1073/Pnas.0704044104  0.434
2007 Pierpont ME, Basson CT, Benson DW, Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL. Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation. 115: 3015-38. PMID 17519398 DOI: 10.1161/Circulationaha.106.183056  0.401
2007 Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN. Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proceedings of the National Academy of Sciences of the United States of America. 104: 7975-80. PMID 17468400 DOI: 10.1073/Pnas.0702447104  0.595
2007 Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell. 129: 303-17. PMID 17397913 DOI: 10.1016/J.Cell.2007.03.030  0.393
2007 Schluterman MK, Krysiak AE, Kathiriya IS, Abate N, Chandalia M, Srivastava D, Garg V. Screening and biochemical analysis of GATA4 sequence variations identified in patients with congenital heart disease. American Journal of Medical Genetics. Part A. 143: 817-23. PMID 17352393 DOI: 10.1002/Ajmg.A.31652  0.644
2007 Zhao Y, Srivastava D. A developmental view of microRNA function. Trends in Biochemical Sciences. 32: 189-197. PMID 17350266 DOI: 10.1016/J.Tibs.2007.02.006  0.332
2007 Ransom J, Srivastava D. The genetics of cardiac birth defects Seminars in Cell and Developmental Biology. 18: 132-139. PMID 17240175 DOI: 10.1016/J.Semcdb.2006.12.005  0.435
2006 Srivastava D. Genetic regulation of cardiogenesis and congenital heart disease Annual Review of Pathology. 1: 199-213. PMID 18039113 DOI: 10.1146/Annurev.Pathol.1.110304.100039  0.468
2006 Ramana KV, Willis MS, White MD, Horton JW, DiMaio JM, Srivastava D, Bhatnagar A, Srivastava SK. Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition. Circulation. 114: 1838-46. PMID 17030682 DOI: 10.1161/Circulationaha.106.630830  0.301
2006 Srivastava D. Making or Breaking the Heart: From Lineage Determination to Morphogenesis Cell. 126: 1037-1048. PMID 16990131 DOI: 10.1016/J.Cell.2006.09.003  0.454
2006 Srivastava D, Yu S. Stretching to meet needs: integrin-linked kinase and the cardiac pump. Genes & Development. 20: 2327-31. PMID 16951248 DOI: 10.1101/Gad.1472506  0.391
2006 Srivastava D, Ivey KN. Potential of stem-cell-based therapies for heart disease. Nature. 441: 1097-9. PMID 16810246 DOI: 10.1038/Nature04961  0.401
2006 King IN, Kathiriya IS, Murakami M, Nakagawa M, Gardner KA, Srivastava D, Nakagawa O. Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jkappa. Biochemical and Biophysical Research Communications. 345: 446-52. PMID 16682003 DOI: 10.1016/J.Bbrc.2006.04.097  0.341
2006 Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L. Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development (Cambridge, England). 133: 2263-73. PMID 16672333 DOI: 10.1242/Dev.02395  0.344
2006 Yamagishi C, Yamagishi H, Maeda J, Tsuchihashi T, Ivey K, Hu T, Srivastava D. Sonic hedgehog is essential for first pharyngeal arch development. Pediatric Research. 59: 349-54. PMID 16492970 DOI: 10.1203/01.Pdr.0000199911.17287.3E  0.382
2006 Maeda J, Yamagishi H, McAnally J, Yamagishi C, Srivastava D. Tbx1 is regulated by forkhead proteins in the secondary heart field. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 701-10. PMID 16444712 DOI: 10.1002/Dvdy.20686  0.449
2006 Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG. Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nature Genetics. 38: 175-83. PMID 16380715 DOI: 10.1038/Ng1707  0.462
2005 Kwon C, Han Z, Olson EN, Srivastava D. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 18986-91. PMID 16357195 DOI: 10.1073/Pnas.0509535102  0.596
2005 Costantini DL, Arruda EP, Agarwal P, Kim KH, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir MG, Cheng SH, ... ... Srivastava D, et al. The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell. 123: 347-58. PMID 16239150 DOI: 10.1016/J.Cell.2005.08.004  0.448
2005 Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, Grossfeld PD, Srivastava D. Mutations in NOTCH1 cause aortic valve disease. Nature. 437: 270-4. PMID 16025100 DOI: 10.1038/Nature03940  0.62
2005 Zhao Y, Samal E, Srivastava D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature. 436: 214-20. PMID 15951802 DOI: 10.1038/Nature03817  0.431
2005 Aiyer AR, Honarpour N, Herz J, Srivastava D. Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype. Developmental Biology. 278: 155-62. PMID 15649468 DOI: 10.1016/J.Ydbio.2004.11.001  0.378
2005 McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN. The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development (Cambridge, England). 132: 189-201. PMID 15576406 DOI: 10.1242/Dev.01562  0.588
2004 Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. 432: 466-72. PMID 15565145 DOI: 10.1038/Nature03000  0.708
2004 Kathiriya IS, King IN, Murakami M, Nakagawa M, Astle JM, Gardner KA, Gerard RD, Olson EN, Srivastava D, Nakagawa O. Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. The Journal of Biological Chemistry. 279: 54937-43. PMID 15485867 DOI: 10.1074/Jbc.M409879200  0.561
2004 Hu T, Yamagishi H, Maeda J, McAnally J, Yamagishi C, Srivastava D. Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development (Cambridge, England). 131: 5491-502. PMID 15469978 DOI: 10.1242/Dev.01399  0.492
2004 Cowan CA, Yokoyama N, Saxena A, Chumley MJ, Silvany RE, Baker LA, Srivastava D, Henkemeyer M. Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Developmental Biology. 271: 263-71. PMID 15223333 DOI: 10.1016/J.Ydbio.2004.03.026  0.68
2004 Srivastava D. An ongoing genetic battle? Nature. 429: 819-822. PMID 15215849 DOI: 10.1038/429819A  0.349
2003 Yamagishi H, Srivastava D. Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome. Trends in Molecular Medicine. 9: 383-9. PMID 13129704 DOI: 10.1016/S1471-4914(03)00141-2  0.341
2003 Srivastava D, Gottlieb PD, Olson EN. Molecular mechanisms of ventricular hypoplasia. Cold Spring Harbor Symposia On Quantitative Biology. 67: 121-5. PMID 12858532 DOI: 10.1101/Sqb.2002.67.121  0.568
2003 Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, Butler CA, Rothrock CR, Eapen RS, Hirayama-Yamada K, Joo K, Matsuoka R, Cohen JC, Srivastava D. GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature. 424: 443-7. PMID 12845333 DOI: 10.1038/Nature01827  0.672
2003 Ivey K, Tyson B, Ukidwe P, McFadden DG, Levi G, Olson EN, Srivastava D, Wilkie TM. Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme. Developmental Biology. 255: 230-7. PMID 12648486 DOI: 10.1016/S0012-1606(02)00097-0  0.457
2003 Yamagishi C, Hierck BP, Groot ACG, Yamagishi H, Srivastava D. Functional Attenuation of Ufd1l, a 22q11.2 Deletion Syndrome Candidate Gene, Leads to Cardiac Outflow Septation Defects in Chicken Embryos Pediatric Research. 53: 546-553. PMID 12612215 DOI: 10.1203/01.Pdr.0000055765.11310.E3  0.437
2003 Srivastava D. Building a heart: Implications for congenital heart disease Journal of Nuclear Cardiology. 10: 63-70. PMID 12569333 DOI: 10.1067/Mnc.2003.25  0.39
2003 Yamagishi H, Maeda J, Hu T, McAnally J, Conway SJ, Kume T, Meyers EN, Yamagishi C, Srivastava D. Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes & Development. 17: 269-81. PMID 12533514 DOI: 10.1101/Gad.1048903  0.392
2002 Villanueva MP, Aiyer AR, Muller S, Pletcher MT, Liu X, Emanuel B, Srivastava D, Reeves RH. Genetic and comparative mapping of genes dysregulated in mouse hearts lacking the Hand2 transcription factor gene Genomics. 80: 593-600. PMID 12504851 DOI: 10.1006/Geno.2002.7009  0.408
2002 Abe M, Tamamura Y, Yamagishi H, Maeda T, Kato J, Tabata MJ, Srivastava D, Wakisaka S, Kurisu K. Tooth-type specific expression of dHAND/Hand2: possible involvement in murine lower incisor morphogenesis. Cell and Tissue Research. 310: 201-12. PMID 12397375 DOI: 10.1007/S00441-002-0611-2  0.388
2002 Gottlieb PD, Pierce SA, Sims RJ, Yamagishi H, Weihe EK, Harriss JV, Maika SD, Kuziel WA, King HL, Olson EN, Nakagawa O, Srivastava D. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nature Genetics. 31: 25-32. PMID 11923873 DOI: 10.1038/Ng866  0.577
2002 Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, Srivastava D. The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Developmental Biology. 239: 190-203. PMID 11784028 DOI: 10.1006/Dbio.2001.0417  0.598
2001 Srivastava DN, Saxena AK, Kriplani A, Agarwal N. Angioembolisation in vaginal vascular malformation. Journal of Postgraduate Medicine. 47: 33-4. PMID 11590289  0.596
2001 Kunte A, Ivey K, Yamagishi C, Garg V, Yamagishi H, Srivastava D. A common cis-acting sequence in the DiGeorge critical region regulates bi-directional transcription of UFD1L and CDC45L Mechanisms of Development. 108: 81-92. PMID 11578863 DOI: 10.1016/S0925-4773(01)00489-0  0.622
2001 Natarajan A, Yamagishi H, Ahmad F, Li D, Roberts R, Matsuoka R, Hill S, Srivastava D. Human eHAND, but not dHAND, is down-regulated in cardiomyopathies Journal of Molecular and Cellular Cardiology. 33: 1607-1614. PMID 11549340 DOI: 10.1006/Jmcc.2001.1434  0.468
2001 Garg V, Yamagishi C, Hu T, Kathiriya IS, Yamagishi H, Srivastava D. Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development. Developmental Biology. 235: 62-73. PMID 11412027 DOI: 10.1006/Dbio.2001.0283  0.643
2001 Liu ZP, Nakagawa O, Nakagawa M, Yanagisawa H, Passier R, Richardson JA, Srivastava D, Olson EN. CHAMP, a novel cardiac-specific helicase regulated by MEF2C. Developmental Biology. 234: 497-509. PMID 11397016 DOI: 10.1006/Dbio.2001.0277  0.605
2001 Srivastava D. Genetic assembly of the heart: Implications for congenital heart disease Annual Review of Physiology. 63: 451-469. PMID 11181963 DOI: 10.1146/Annurev.Physiol.63.1.451  0.413
2000 Kathiriya IS, Srivastava D. Left-right asymmetry and cardiac looping: implications for cardiac development and congenital heart disease. American Journal of Medical Genetics. 97: 271-279. PMID 11376438 DOI: 10.1002/1096-8628(200024)97:4<271::Aid-Ajmg1277>3.0.Co;2-O  0.426
2000 Nakagawa O, McFadden DG, Nakagawa M, Yanagisawa H, Hu T, Srivastava D, Olson EN. Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 97: 13655-60. PMID 11095750 DOI: 10.1073/Pnas.250485597  0.512
2000 Fisher SA, Langille BL, Srivastava D. Apoptosis during cardiovascular development Circulation Research. 87: 856-864. PMID 11073880 DOI: 10.1161/01.Res.87.10.856  0.395
2000 Srivastava D, Olson EN. A genetic blueprint for cardiac development Nature. 407: 221-226. PMID 11001064 DOI: 10.1038/35025190  0.581
2000 Angelo S, Lohr J, Lee KH, Ticho BS, Breitbart RE, Hill S, Yost HJ, Srivastava D. Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development. Mechanisms of Development. 95: 231-7. PMID 10906469 DOI: 10.1016/S0925-4773(00)00334-8  0.42
2000 Srivastava D. Congenital heart defects: Trapping the genetic culprits Circulation Research. 86: 917-918. PMID 10807859 DOI: 10.1161/01.Res.86.9.917  0.381
2000 Yamagishi H, Olson EN, Srivastava D. The basic helix-loop-helix transcription factor, dHAND, is required for vascular development. The Journal of Clinical Investigation. 105: 261-70. PMID 10675351 DOI: 10.1172/Jci8856  0.485
2000 Nakagawa O, Nakagawa M, Richardson JA, Olson EN, Srivastava D. HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Developmental Biology. 216: 72-84. PMID 10588864 DOI: 10.1006/Dbio.1999.9454  0.551
1999 Srivastava D. Developmental and genetic aspects of congenital heart disease Current Opinion in Cardiology. 14: 263-268. PMID 10358798 DOI: 10.1097/00001573-199905000-00011  0.504
1999 Srivastava D. HAND proteins: Molecular mediators of cardiac development and congenital heart disease Trends in Cardiovascular Medicine. 9: 11-18. PMID 10189962 DOI: 10.1016/S1050-1738(98)00033-4  0.491
1999 Yamagishi H, Garg V, Matsuoka R, Thomas T, Srivastava D. A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects. Science (New York, N.Y.). 283: 1158-61. PMID 10024240 DOI: 10.1126/Science.283.5405.1158  0.63
1998 Thomas T, Yamagishi H, Overbeek PA, Olson EN, Srivastava D. The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness. Developmental Biology. 196: 228-36. PMID 9576835 DOI: 10.1006/Dbio.1998.8849  0.55
1998 Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nature Genetics. 18: 266-70. PMID 9500550 DOI: 10.1038/Ng0398-266  0.743
1998 Srivastava D, Thomas T. Hypoplastic Right Ventricle in dHAND Mutants is the Result of Cytochrome C Mediated Apoptosis of Cardiomyocytes. |[bull]| 142 Pediatric Research. 43: 27-27. DOI: 10.1203/00006450-199804001-00163  0.446
1998 Srivastava D. Role of the Transcription Factors dHAND and eHAND in Cardiac Morphogenesis Pediatric Cardiology. 19: 160-160. DOI: 10.1007/S002469900266  0.401
1997 Srivastava D, Thomas T, Kirby ML, Brown D, Olson EN. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND Nature Genetics. 16: 154-160. PMID 9171826 DOI: 10.1038/Ng0697-154  0.602
1997 Thomas T, Lin Q, Olson E, Srivastava D. REGULATION OF RIGHT VENTRICLE AND AORTIC ARCH FORMATION BY THE bHLH PROTEIN, dHAND • 145 Pediatric Research. 41: 27-27. DOI: 10.1203/00006450-199704001-00165  0.602
1997 Lin Q, Srivastava D, Olson EN. A transcriptional pathway for cardiac development. Cold Spring Harbor Symposia On Quantitative Biology. 62: 405-411. DOI: 10.1101/Sqb.1997.062.01.048  0.552
1996 Srivastava D, Olson EN. Neurotrophin-3 knocks heart off Trk Nature Medicine. 2: 1069-1071. PMID 8837596 DOI: 10.1038/Nm1096-1069  0.524
1996 Olson EN, Srivastava D. Molecular pathways controlling heart development Science. 272: 671-676. PMID 8614825 DOI: 10.1126/Science.272.5262.671  0.582
1996 Srivastava D, Kurihara H, Olson EN. A MOUSE MODEL FOR THE DIGEORGE PHENOTYPE ASSOCIATED WITH ABNORMALITIES OF THEHAND GENES. • 212 Pediatric Research. 39: 38-38. DOI: 10.1203/00006450-199604001-00231  0.569
1995 Srivastava D, Cserjesi P, Olson EN. A subclass of bHLH proteins required for cardiac morphogenesis Science. 270: 1995-1999. PMID 8533092 DOI: 10.1126/Science.270.5244.1995  0.578
1995 Srivastava D, Preminger T, Lock JE, Mandell V, Keane JF, Mayer JE, Kozakewich H, Spevak PJ. Hepatic venous blood and the development of pulmonary arteriovenous malformations in congenital heart disease. Circulation. 92: 1217-22. PMID 7648668 DOI: 10.1161/01.Cir.92.5.1217  0.326
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