Hans George Othmer - Publications

Affiliations: 
Mathematics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
pattern formation in development, calcium dynamics in neural tissue, cell-based and continuum descriptions of cell and tissue movement, analysis of complex metabolic and gene-control networks, and mathematical models of tumor angiogenesis
Website:
http://www.math.umn.edu/pacim/othmer.html

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cheng Y, Felix B, Othmer HG. The Roles of Signaling in Cytoskeletal Changes, Random Movement, Direction-Sensing and Polarization of Eukaryotic Cells. Cells. 9. PMID 32531876 DOI: 10.3390/Cells9061437  0.335
2020 McKinney MC, McLennan R, Giniunaite R, Baker RE, Maini PK, Othmer HG, Kulesa PM. Visualizing mesoderm and neural crest cell dynamics during chick head morphogenesis. Developmental Biology. PMID 32084354 DOI: 10.1016/J.Ydbio.2020.02.010  0.349
2020 Gou J, Stotsky JA, Othmer HG. Growth control in the Drosophila wing disk. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. e1478. PMID 31917525 DOI: 10.1002/Wsbm.1478  0.37
2019 Kim Y, Lee J, Lee D, Othmer HG. Synergistic Effects of Bortezomib-OV Therapy and Anti-Invasive Strategies in Glioblastoma: A Mathematical Model. Cancers. 11. PMID 30781871 DOI: 10.3390/Cancers11020215  0.619
2018 Othmer HG. Eukaryotic Cell Dynamics from Crawlers to Swimmers. Wiley Interdisciplinary Reviews. Computational Molecular Science. 9. PMID 30854030 DOI: 10.1002/Wcms.1376  0.319
2018 Gou J, Lin L, Othmer HG. A Model for the Hippo Pathway in the Drosophila Wing Disc. Biophysical Journal. PMID 30041810 DOI: 10.1016/J.Bpj.2018.07.002  0.38
2018 Wang Q, Othmer HG. Analysis of a model microswimmer with applications to blebbing cells and mini-robots. Journal of Mathematical Biology. PMID 29497820 DOI: 10.1007/S00285-018-1225-Y  0.649
2018 PLESA T, ERBAN R, OTHMER HG. Noise-induced mixing and multimodality in reaction networks European Journal of Applied Mathematics. 30: 887-911. DOI: 10.1017/S0956792518000517  0.639
2017 Lin L, Othmer HG. Improving Parameter Inference from FRAP Data: an Analysis Motivated by Pattern Formation in the Drosophila Wing Disc. Bulletin of Mathematical Biology. PMID 28101740 DOI: 10.1007/S11538-016-0241-6  0.339
2016 Kim Y, Jeon H, Othmer H. The role of the tumor microenvironment in glioblastoma: A mathematical model. Ieee Transactions On Bio-Medical Engineering. PMID 27959794 DOI: 10.1109/Tbme.2016.2637828  0.651
2016 Bretschneider T, Othmer HG, Weijer CJ. Progress and perspectives in signal transduction, actin dynamics, and movement at the cell and tissue level: lessons from Dictyostelium. Interface Focus. 6: 20160047. PMID 27708767 DOI: 10.1098/Rsfs.2016.0047  0.358
2016 Cheng Y, Othmer H. A Model for Direction Sensing in Dictyostelium discoideum: Ras Activity and Symmetry Breaking Driven by a Gβγ-Mediated, Gα2-Ric8 -- Dependent Signal Transduction Network. Plos Computational Biology. 12: e1004900. PMID 27152956 DOI: 10.1371/Journal.Pcbi.1004900  0.373
2016 Kan X, Lee CH, Othmer HG. A multi-time-scale analysis of chemical reaction networks: II. Stochastic systems. Journal of Mathematical Biology. PMID 26945582 DOI: 10.1007/S00285-016-0980-X  0.317
2016 Othmer HG. Cell-Based, Continuum and Hybrid Models of Tissue Dynamics Lecture Notes in Mathematics. 2167: 1-72. DOI: 10.1007/978-3-319-42679-2_1  0.378
2015 Wang Q, Othmer HG. The performance of discrete models of low reynolds number swimmers. Mathematical Biosciences and Engineering : Mbe. 12: 1303-20. PMID 26775865 DOI: 10.3934/Mbe.2015.12.1303  0.654
2015 Kim Y, Othmer HG. Hybrid models of cell and tissue dynamics in tumor growth. Mathematical Biosciences and Engineering : Mbe. 12: 1141-56. PMID 26775860 DOI: 10.3934/Mbe.2015.12.1141  0.652
2015 Wang Q, Othmer HG. Computational analysis of amoeboid swimming at low Reynolds number. Journal of Mathematical Biology. PMID 26362281 DOI: 10.1007/S00285-015-0925-9  0.668
2015 Sanft KR, Othmer HG. Constant-complexity stochastic simulation algorithm with optimal binning. The Journal of Chemical Physics. 143: 074108. PMID 26298116 DOI: 10.1063/1.4928635  0.331
2015 Averina VA, Othmer HG, Fink GD, Osborn JW. A mathematical model of salt-sensitive hypertension: the neurogenic hypothesis. The Journal of Physiology. 593: 3065-75. PMID 26173827 DOI: 10.1113/Jphysiol.2014.278317  0.748
2015 Umulis DM, Othmer HG. The role of mathematical models in understanding pattern formation in developmental biology. Bulletin of Mathematical Biology. 77: 817-45. PMID 25280665 DOI: 10.1007/S11538-014-0019-7  0.66
2014 Averina VA, Othmer HG, Fink GD, Osborn JW. A mathematical model of salt-sensitive hypertension: the neurogenic hypothesis. The Journal of Physiology. PMID 25217375 DOI: 10.1113/jphysiol.2014.278317  0.737
2014 Erban R, Othmer HG. Editorial: special issue on stochastic modelling of reaction-diffusion processes in biology. Bulletin of Mathematical Biology. 76: 761-5. PMID 24402472 DOI: 10.1007/S11538-013-9929-Z  0.638
2014 Hu J, Kang HW, Othmer HG. Stochastic analysis of reaction-diffusion processes. Bulletin of Mathematical Biology. 76: 854-94. PMID 23719732 DOI: 10.1007/S11538-013-9849-Y  0.588
2013 Umulis DM, Othmer HG. Mechanisms of scaling in pattern formation. Development (Cambridge, England). 140: 4830-43. PMID 24301464 DOI: 10.1242/Dev.100511  0.66
2013 Khamviwath V, Hu J, Othmer HG. A continuum model of actin waves in Dictyostelium discoideum. Plos One. 8: e64272. PMID 23741312 DOI: 10.1371/Journal.Pone.0064272  0.698
2013 Averina VA, Othmer HG, Fink GD, Osborn JW. Reply from V. A. Averina, H. G. Othmer, G. D. Fink and J. W. Osborn. The Journal of Physiology. 591: 2965. PMID 23729798 DOI: 10.1113/Jphysiol.2013.254607  0.738
2013 Othmer HG, Xin X, Xue C. Excitation and Adaptation in Bacteria-a Model Signal Transduction System that Controls Taxis and Spatial Pattern Formation. International Journal of Molecular Sciences. 14: 9205-48. PMID 23624608 DOI: 10.3390/Ijms14059205  0.669
2013 Kim Y, Othmer HG. A hybrid model of tumor-stromal interactions in breast cancer. Bulletin of Mathematical Biology. 75: 1304-50. PMID 23292359 DOI: 10.1007/S11538-012-9787-0  0.653
2013 Othmer HG, Xue C. The mathematical analysis of biological aggregation and dispersal: Progress, problems and perspectives Lecture Notes in Mathematics. 2071: 79-127. DOI: 10.1007/978-3-642-35497-7_4  0.406
2012 Umulis DM, Othmer HG. The importance of geometry in mathematical models of developing systems. Current Opinion in Genetics & Development. 22: 547-52. PMID 23107453 DOI: 10.1016/J.Gde.2012.09.007  0.698
2012 Averina VA, Othmer HG, Fink GD, Osborn JW. A new conceptual paradigm for the haemodynamics of salt-sensitive hypertension: a mathematical modelling approach. The Journal of Physiology. 590: 5975-92. PMID 22890716 DOI: 10.1113/Jphysiol.2012.228619  0.746
2012 Xin X, Othmer HG. A "trimer of dimers"-based model for the chemotactic signal transduction network in bacterial chemotaxis. Bulletin of Mathematical Biology. 74: 2339-82. PMID 22864951 DOI: 10.1007/S11538-012-9756-7  0.581
2012 Kang HW, Zheng L, Othmer HG. The effect of the signalling scheme on the robustness of pattern formation in development. Interface Focus. 2: 465-86. PMID 22649582 DOI: 10.1098/Rsfs.2011.0116  0.551
2012 Kang HW, Zheng L, Othmer HG. A new method for choosing the computational cell in stochastic reaction-diffusion systems. Journal of Mathematical Biology. 65: 1017-99. PMID 22071651 DOI: 10.1007/S00285-011-0469-6  0.512
2012 Umulis DM, Othmer HG. Scale invariance of morphogen-mediated patterning by flux optimization 2012 5th International Conference On Biomedical Engineering and Informatics, Bmei 2012. 1030-1034. DOI: 10.1109/BMEI.2012.6513146  0.597
2011 Xue C, Budrene EO, Othmer HG. Radial and spiral stream formation in Proteus mirabilis colonies. Plos Computational Biology. 7: e1002332. PMID 22219724 DOI: 10.1371/Journal.Pcbi.1002332  0.565
2011 Kim Y, Stolarska MA, Othmer HG. The role of the microenvironment in tumor growth and invasion. Progress in Biophysics and Molecular Biology. 106: 353-79. PMID 21736894 DOI: 10.1016/J.Pbiomolbio.2011.06.006  0.668
2011 Hu J, Othmer HG. A theoretical analysis of filament length fluctuations in actin and other polymers. Journal of Mathematical Biology. 63: 1001-49. PMID 21234568 DOI: 10.1007/S00285-010-0400-6  0.615
2010 Umulis DM, Shimmi O, O'Connor MB, Othmer HG. Organism-scale modeling of early Drosophila patterning via bone morphogenetic proteins. Developmental Cell. 18: 260-74. PMID 20159596 DOI: 10.1016/J.Devcel.2010.01.006  0.687
2010 Lee CH, Othmer HG. A multi-time-scale analysis of chemical reaction networks: I. Deterministic systems. Journal of Mathematical Biology. 60: 387-450. PMID 19350241 DOI: 10.1007/S00285-009-0269-4  0.306
2009 Othmer HG, Painter K, Umulis D, Xue C. The Intersection of Theory and Application in Elucidating Pattern Formation in Developmental Biology. Mathematical Modelling of Natural Phenomena. 4: 3-82. PMID 19844610 DOI: 10.1051/Mmnp/20094401  0.734
2009 Kang M, Othmer HG. Spatiotemporal characteristics of calcium dynamics in astrocytes. Chaos (Woodbury, N.Y.). 19: 037116. PMID 19792041 DOI: 10.1063/1.3206698  0.538
2009 Xue C, Othmer HG. MULTISCALE MODELS OF TAXIS-DRIVEN PATTERNING IN BACTERIAL POPULATIONS. Siam Journal On Applied Mathematics. 70: 133-169. PMID 19784399 DOI: 10.1137/070711505  0.561
2009 Stolarska MA, Kim Y, Othmer HG. Multi-scale models of cell and tissue dynamics. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 3525-53. PMID 19657010 DOI: 10.1098/Rsta.2009.0095  0.665
2009 Xue C, Othmer HG, Erban R. From individual to collective behavior of unicellular organisms: Recent results and open problems Aip Conference Proceedings. 1167: 3-14. DOI: 10.1063/1.3246413  0.644
2008 Serpe M, Umulis D, Ralston A, Chen J, Olson DJ, Avanesov A, Othmer H, O'Connor MB, Blair SS. The BMP-binding protein Crossveinless 2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling in Drosophila. Developmental Cell. 14: 940-53. PMID 18539121 DOI: 10.1016/J.Devcel.2008.03.023  0.652
2008 Umulis D, O'Connor MB, Othmer HG. Robustness of embryonic spatial patterning in Drosophila melanogaster. Current Topics in Developmental Biology. 81: 65-111. PMID 18023724 DOI: 10.1016/S0070-2153(07)81002-7  0.705
2007 Kang M, Othmer HG. The variety of cytosolic calcium responses and possible roles of PLC and PKC. Physical Biology. 4: 325-43. PMID 18185010 DOI: 10.1088/1478-3975/4/4/009  0.476
2007 Matzavinos A, Othmer HG. A stochastic analysis of actin polymerization in the presence of twinfilin and gelsolin. Journal of Theoretical Biology. 249: 723-36. PMID 17931658 DOI: 10.1016/J.Jtbi.2007.08.018  0.302
2007 Erban R, Othmer HG. Taxis equations for amoeboid cells. Journal of Mathematical Biology. 54: 847-85. PMID 17273880 DOI: 10.1007/S00285-007-0070-1  0.644
2007 Yangjin K, Stolarska MA, Othmer HG. A hybrid model for tumor spheroid growth in vitro I: Theoretical development and early results Mathematical Models and Methods in Applied Sciences. 17: 1773-1798. DOI: 10.1142/S0218202507002479  0.353
2007 Hu J, Matzavinos A, Othmer HG. A theoretical approach to actin filament dynamics Journal of Statistical Physics. 128: 111-138. DOI: 10.1007/S10955-006-9204-X  0.61
2006 Umulis DM, Serpe M, O'Connor MB, Othmer HG. Robust, bistable patterning of the dorsal surface of the Drosophila embryo. Proceedings of the National Academy of Sciences of the United States of America. 103: 11613-8. PMID 16864795 DOI: 10.1073/Pnas.0510398103  0.682
2006 Soto G, Othmer HG. A model for a G-protein-mediated mechanism for synaptic channel modulation. Mathematical Biosciences. 200: 188-213. PMID 16540128 DOI: 10.1016/J.Mbs.2006.01.005  0.754
2006 O'Connor MB, Umulis D, Othmer HG, Blair SS. Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing. Development (Cambridge, England). 133: 183-93. PMID 16368928 DOI: 10.1242/Dev.02214  0.674
2006 Erban R, Kevrekidis IG, Othmer HG. An equation-free computational approach for extracting population-level behavior from individual-based models of biological dispersal Physica D: Nonlinear Phenomena. 215: 1-24. DOI: 10.1016/J.Physd.2006.01.008  0.698
2005 Shimmi O, Umulis D, Othmer H, O'Connor MB. Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo Cell. 120: 873-886. PMID 15797386 DOI: 10.1016/J.Cell.2005.02.009  0.671
2005 Erban R, Othmer HG. From individual to collective behavior in bacterial chemotaxis Siam Journal On Applied Mathematics. 65: 361-391. DOI: 10.1137/S0036139903433232  0.647
2005 Erban R, Othmer HG. From signal transduction to spatial pattern formation in E. coli: A paradigm for multiscale modeling in biology Multiscale Modeling and Simulation. 3: 362-394. DOI: 10.1137/040603565  0.637
2005 Setayeshgar S, Gear CW, Othmer HG, Kevrekidis IG. Application of coarse integration to bacterial chemotaxis Multiscale Modeling and Simulation. 4: 307-327. DOI: 10.1137/030600874  0.527
2005 Shimmi O, Umulis D, Othmer HG, O'Connor MB. Erratum: Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo (Cell (2005) 120 (873-886) ) Cell. 121. DOI: 10.1016/J.Cell.2005.04.022  0.651
2004 Dallon JC, Othmer HG. How cellular movement determines the collective force generated by the Dictyostelium discoideum slug. Journal of Theoretical Biology. 231: 203-22. PMID 15380385 DOI: 10.1016/J.Jtbi.2004.06.015  0.343
2004 Albert R, Chiu YW, Othmer HG. Dynamic receptor team formation can explain the high signal transduction gain in Escherichia coli. Biophysical Journal. 86: 2650-9. PMID 15111386 DOI: 10.1016/S0006-3495(04)74321-0  0.388
2004 Gracheva ME, Othmer HG. A continuum model of motility in ameboid cells. Bulletin of Mathematical Biology. 66: 167-93. PMID 14670535 DOI: 10.1016/J.Bulm.2003.08.007  0.356
2004 Horstmann D, Painter KJ, Othmer HG. Aggregation under local reinforcement: From lattice to continuum European Journal of Applied Mathematics. 15: 545-576. DOI: 10.1017/S0956792504005571  0.335
2003 Dillon R, Gadgil C, Othmer HG. Short- and long-range effects of Sonic hedgehog in limb development. Proceedings of the National Academy of Sciences of the United States of America. 100: 10152-7. PMID 12930894 DOI: 10.1073/Pnas.1830500100  0.729
2003 Albert R, Othmer HG. The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster. Journal of Theoretical Biology. 223: 1-18. PMID 12782112 DOI: 10.1016/S0022-5193(03)00035-3  0.339
2000 Painter KJ, Maini PK, Othmer HG. Development and applications of a model for cellular response to multiple chemotactic cues. Journal of Mathematical Biology. 41: 285-314. PMID 11103868 DOI: 10.1007/S002850000035  0.371
2000 Palsson E, Othmer HG. A model for individual and collective cell movement in Dictyostelium discoideum. Proceedings of the National Academy of Sciences of the United States of America. 97: 10448-53. PMID 10984537 DOI: 10.1073/Pnas.97.19.10448  0.379
2000 Painter KJ, Maini PK, Othmer HG. A chemotactic model for the advance and retreat of the primitive streak in avian development. Bulletin of Mathematical Biology. 62: 501-25. PMID 10812719 DOI: 10.1006/Bulm.1999.0166  0.378
1999 Painter KJ, Maini PK, Othmer HG. Stripe formation in juvenile Pomacanthus explained by a generalized turing mechanism with chemotaxis. Proceedings of the National Academy of Sciences of the United States of America. 96: 5549-54. PMID 10318921 DOI: 10.1073/Pnas.96.10.5549  0.39
1999 Dillon R, Othmer HG. A mathematical model for outgrowth and spatial patterning of the vertebrate limb bud. Journal of Theoretical Biology. 197: 295-330. PMID 10089144 DOI: 10.1006/Jtbi.1998.0876  0.728
1998 Dallon JC, Othmer HG. A continuum analysis of the chemotactic signal seen by Dictyostelium discoideum. Journal of Theoretical Biology. 194: 461-83. PMID 9790824 DOI: 10.1006/Jtbi.1998.0766  0.372
1997 Spiro PA, Parkinson JS, Othmer HG. A model of excitation and adaptation in bacterial chemotaxis. Proceedings of the National Academy of Sciences of the United States of America. 94: 7263-8. PMID 9207079 DOI: 10.1073/Pnas.94.14.7263  0.336
1997 Dallon JC, Othmer HG. A discrete cell model with adaptive signalling for aggregation of Dictyostelium discoideum. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 352: 391-417. PMID 9134569 DOI: 10.1098/Rstb.1997.0029  0.39
1997 Othmer HG, Stevens A. Aggregation, blowup, and collapse: The ABC'S of taxis in reinforced random walks Siam Journal On Applied Mathematics. 57: 1044-1081. DOI: 10.1137/S0036139995288976  0.335
1996 Schaap P, Tang Y, Othmer HG. A model for pattern formation in Dictyostelium discoideum Differentiation. 60: 1-16. DOI: 10.1046/J.1432-0436.1996.6010001.X  0.382
1996 Schaap P, Tang Y, Othmer HG. Erratum: A model for pattern formation in Dictyostelium discoideum (Differentiation (1996) 60 (1-16)) Differentiation. 61. DOI: 10.1007/S002580050178  0.336
1995 Tang Y, Othmer HG. Excitation, oscillations and wave propagation in a G-protein-based model of signal transduction in Dictyostelium discoideum. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 349: 179-95. PMID 8668725 DOI: 10.1098/Rstb.1995.0102  0.381
1994 Tang Y, Othmer HG. A G protein-based model of adaptation in Dictyostelium discoideum. Mathematical Biosciences. 120: 25-76. PMID 8155908 DOI: 10.1016/0025-5564(94)90037-X  0.365
1994 Dillon R, Maini PK, Othmer HG. Pattern formation in generalized Turing systems: I. Steady-state patterns in systems with mixed boundary conditions Journal of Mathematical Biology. 32: 345-393. DOI: 10.1007/Bf00160165  0.684
1989 Monk PB, Othmer HG. Cyclic AMP oscillations in suspensions of Dictyostelium discoideum. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 323: 185-224. PMID 2565584 DOI: 10.1098/Rstb.1989.0005  0.37
1989 Othmer HG. Mathematical models in biology Mathematical Biosciences. 96: 131-133. DOI: 10.1016/0025-5564(89)90088-6  0.312
1988 Othmer HG, Dunbar SR, Alt W. Models of dispersal in biological systems. Journal of Mathematical Biology. 26: 263-98. PMID 3411255 DOI: 10.1007/Bf00277392  0.339
1988 DeYoung G, Monk PB, Othmer HG. Pacemakers in aggregation fields of Dictyostelium discoideum: does a single cell suffice? Journal of Mathematical Biology. 26: 487-517. PMID 3209953 DOI: 10.1007/Bf00276057  0.354
1986 Othmer HG. On the Newman-Frisch model of limb chondrogenesis. Journal of Theoretical Biology. 121: 505-8. PMID 3796004 DOI: 10.1016/S0022-5193(86)80105-9  0.313
1986 Pate EF, Othmer HG. Differentiation, cell sorting and proportion regulation in the slug stage of Dictyostelium discoideum. Journal of Theoretical Biology. 118: 301-19. PMID 3713214 DOI: 10.1016/S0022-5193(86)80061-3  0.379
1985 Othmer HG, Monk PB, Rapp PE. A model for signal-relay adaptation in Dictyostelium discoideum. II. Analytical and numerical results Mathematical Biosciences. 77: 79-139. DOI: 10.1016/0025-5564(85)90092-6  0.303
1985 Rapp PE, Monk PB, Othmer HG. A model for signal-relay adaptation in Dictyostelium discoideum. I. Biological processes and the model network Mathematical Biosciences. 77: 35-78. DOI: 10.1016/0025-5564(85)90091-4  0.356
1984 Pate E, Othmer HG. Applications of a model for scale-invariant pattern formation in developing systems. Differentiation; Research in Biological Diversity. 28: 1-8. PMID 6519366 DOI: 10.1111/J.1432-0436.1984.Tb00259.X  0.386
1983 Othmer HG. A continuum model for coupled cells. Journal of Mathematical Biology. 17: 351-69. PMID 6619666 DOI: 10.1007/Bf00276521  0.35
1978 Othmer HG, Aldridge JA. The effects of cell density and metabolite flux on cellular dynamics. Journal of Mathematical Biology. 5: 169-200. PMID 366054 DOI: 10.1007/Bf00275897  0.333
1977 Ashkenazi M, Othmer HG. Spatial patterns in coupled biochemical oscillators Journal of Mathematical Biology. 5: 305-350. DOI: 10.1007/Bf00276105  0.309
1975 Othmer HG. On the temporal characteristics of a model for the Zhabotinskii-Belousov reaction Mathematical Biosciences. 24: 205-238. DOI: 10.1016/0025-5564(75)90076-0  0.32
1975 Othmer HG. Nonlinear wave propagation in reacting systems Journal of Mathematical Biology. 2: 133-163. DOI: 10.1007/Bf00275925  0.339
1974 Othmer HG, Scriven LE. Non-linear aspects of dynamic pattern in cellular networks. Journal of Theoretical Biology. 43: 83-112. PMID 4813541 DOI: 10.1016/S0022-5193(74)80047-0  0.709
1971 Othmer HG, Scriven LE. Instability and dynamic pattern in cellular networks. Journal of Theoretical Biology. 32: 507-37. PMID 5571122 DOI: 10.1016/0022-5193(71)90154-8  0.703
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