| Year |
Citation |
Score |
| 2022 |
Wang S, Lee K, Gray S, Zhang Y, Tang C, Morrish RB, Tosti E, van Oers J, Amin MR, Cohen PE, MacCarthy T, Roa S, Scharff MD, Edelmann W, Chahwan R. Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice. Nucleic Acids Research. PMID 35849338 DOI: 10.1093/nar/gkac616 |
0.512 |
|
| 2022 |
Tosti E, Almeida AS, Tran TTT, Silva MBE, Broin PÓ, Dubin R, Chen K, Beck AP, Mclellan AS, Sanchez EV, Golden A, O'Toole PW, Edelmann W. Loss of MMR and TGFBR2 increases the susceptibility to microbiota-dependent inflammation-associated colon cancer. Cellular and Molecular Gastroenterology and Hepatology. PMID 35688320 DOI: 10.1016/j.jcmgh.2022.05.010 |
0.427 |
|
| 2022 |
Schubert N, Schumann T, Daum E, Flade K, Ge Y, Hagedorn L, Edelmann W, Müller L, Schmitz M, Kuut G, Hornung V, Behrendt R, Roers A. Genome Replication Is Associated With Release of Immunogenic DNA Waste. Frontiers in Immunology. 13: 880413. PMID 35634291 DOI: 10.3389/fimmu.2022.880413 |
0.382 |
|
| 2021 |
Gebert J, Gelincik O, Oezcan-Wahlbrink M, Marshall JD, Hernandez-Sanchez A, Urban K, Long M, Cortes E, Tosti E, Katzenmaier EM, Song Y, Elsaadi A, Deng N, Vilar E, Fuchs V, ... ... Edelmann W, et al. Recurrent frameshift neoantigen vaccine elicits protective immunity with reduced tumor burden and improved overall survival in a Lynch syndrome mouse model. Gastroenterology. PMID 34224739 DOI: 10.1053/j.gastro.2021.06.073 |
0.322 |
|
| 2021 |
Bommi PV, Bowen CM, Reyes-Uribe L, Wu W, Katayama H, Rocha P, Parra ER, Francisco-Cruz A, Ozcan Z, Tosti E, Willis JA, Wu H, Taggart MW, Burks JK, Lynch PM, ... Edelmann W, et al. The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells. Cancer Research. 81: 2760-2773. PMID 34003775 DOI: 10.1158/0008-5472.CAN-20-2896 |
0.301 |
|
| 2020 |
Ene AC, Park S, Edelmann W, Taketo T. Corrigendum to "Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression" [Dev. Biol. Vol.377 (2013) 213-223]. Developmental Biology. PMID 32800616 DOI: 10.1016/J.Ydbio.2020.08.001 |
0.314 |
|
| 2020 |
Yamada S, Hinch AG, Kamido H, Zhang Y, Edelmann W, Keeney S. Molecular structures and mechanisms of DNA break processing in mouse meiosis. Genes & Development. PMID 32354835 DOI: 10.1101/Gad.336032.119 |
0.45 |
|
| 2019 |
Milano CR, Holloway JK, Zhang Y, Jin B, Smith C, Bergman A, Edelmann W, Cohen PE. Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis. G3 (Bethesda, Md.). PMID 30944090 DOI: 10.1534/G3.119.400074 |
0.493 |
|
| 2019 |
Yasuda M, Gan L, Chen B, Yu C, Zhang J, Gama-Sosa MA, Pollak DD, Berger S, Phillips JD, Edelmann W, Desnick RJ. Homozygous hydroxymethylbilane synthase knock-in mice provide pathogenic insights into the severe neurological impairments present in human homozygous dominant acute intermittent porphyria. Human Molecular Genetics. PMID 30615115 DOI: 10.1093/Hmg/Ddz003 |
0.427 |
|
| 2018 |
Zhao X, Zhang Y, Wilkins K, Edelmann W, Usdin K. MutLγ promotes repeat expansion in a Fragile X mouse model while EXO1 is protective. Plos Genetics. 14: e1007719. PMID 30312299 DOI: 10.1371/Journal.Pgen.1007719 |
0.52 |
|
| 2017 |
Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM. Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair. Oncotarget. 8: 71574-71586. PMID 29069730 DOI: 10.18632/Oncotarget.17776 |
0.549 |
|
| 2017 |
Chen CC, Avdievich E, Zhang Y, Zhang Y, Wei K, Lee K, Edelmann W, Jasin M, LaRocque JR. EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells. Dna Repair. 57: 98-106. PMID 28711786 DOI: 10.1016/J.Dnarep.2017.07.003 |
0.791 |
|
| 2017 |
Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM. Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair. Oncotarget. PMID 28548965 DOI: 10.18632/oncotarget.17776 |
0.461 |
|
| 2017 |
Kokavec J, Zikmund T, Savvulidi F, Kulvait V, Edelmann W, Skoultchi AI, Stopka T. Smarca5 (Snf2h) is required for Proliferation of Hematopoietic Stem Cells Differentiating into Erythroid and Myeloid lineages. Stem Cells (Dayton, Ohio). PMID 28276606 DOI: 10.1002/Stem.2604 |
0.42 |
|
| 2016 |
Zhang Y, Fox JT, Park YU, Elliott G, Rai G, Cai M, Sakamuru S, Huang R, Xia M, Lee K, Jeon MH, Mathew BP, Park HD, Edelmann W, Park CY, et al. A novel chemotherapeutic agent to treat tumors with DNA mismatch repair deficiencies. Cancer Research. PMID 27262172 DOI: 10.1158/0008-5472.Can-15-2974 |
0.622 |
|
| 2016 |
Eso Y, Takai A, Matsumoto T, Inuzuka T, Horie T, Ono K, Uemoto S, Lee K, Edelmann W, Chiba T, Marusawa H. MSH2 dysregulation is triggered by proinflammatory cytokine stimulation and is associated with liver cancer development. Cancer Research. PMID 27261510 DOI: 10.1158/0008-5472.Can-15-2926 |
0.534 |
|
| 2016 |
Borras E, San Lucas FA, Chang K, Zhou R, Masand G, Fowler J, Mork ME, You YN, Taggart MW, McAllister F, Jones DA, Davies GE, Edelmann W, Ehli EA, Lynch PM, et al. Genomic Landscape of Colorectal Mucosa and Adenomas. Cancer Prevention Research (Philadelphia, Pa.). PMID 27221540 DOI: 10.1158/1940-6207.Capr-16-0081 |
0.402 |
|
| 2015 |
Lee K, Tosti E, Edelmann W. Mouse models of DNA mismatch repair in cancer research. Dna Repair. PMID 26708047 DOI: 10.1016/J.Dnarep.2015.11.015 |
0.609 |
|
| 2015 |
Will B, Vogler TO, Narayanagari S, Bartholdy B, Todorova TI, da Silva Ferreira M, Chen J, Yu Y, Mayer J, Barreyro L, Carvajal L, Neriah DB, Roth M, van Oers J, Schaetzlein S, ... ... Edelmann W, et al. Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia. Nature Medicine. PMID 26343801 DOI: 10.1038/Nm.3936 |
0.433 |
|
| 2015 |
Rein K, Yanez DA, Terré B, Palenzuela L, Aivio S, Wei K, Edelmann W, Stark JM, Stracker TH. EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele. Nucleic Acids Research. PMID 26160886 DOI: 10.1093/Nar/Gkv691 |
0.529 |
|
| 2015 |
Chen HJ, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, Joe DJ, Choi J, Gadamsetty P, Milsom J, Nandakumar G, Longman R, Zhou XK, Edwards R, Chen J, ... ... Edelmann W, et al. Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. Nature Biotechnology. 33: 656-60. PMID 26006007 DOI: 10.1038/Nbt.3239 |
0.446 |
|
| 2015 |
Kortüm B, Campregher C, Lang M, Khare V, Pinter M, Evstatiev R, Schmid G, Mittlböck M, Scharl T, Kucherlapati MH, Edelmann W, Gasche C. Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2loxP/loxP Villin-Cre mice. Gut. 64: 1905-12. PMID 25429050 DOI: 10.1136/Gutjnl-2014-307663 |
0.532 |
|
| 2015 |
Graver S, Stremitzer S, Sunakawa Y, Edelmann W, Kockx M, Schartl M, Scherer SJ, Lenz H, Mazzone M. Immune response triggered by a novel molecular crosstalk of major hallmarks of cancer: Angiogenesis, mismatch repair, and immune pathways. Journal of Clinical Oncology. 33: 11054-11054. DOI: 10.1200/Jco.2015.33.15_Suppl.11054 |
0.432 |
|
| 2015 |
Lipkin SM, Chen HJ, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, Joe D, Choi J, Gadamsetty P, Milsom J, Nandakumar G, Longman R, Zhou K, Edwards R, ... ... Edelmann W, et al. Abstract 2891: Chemokine-targeted models of human orthotopic colorectal cancer in immunocompetant mice Cancer Research. 75: 2891-2891. DOI: 10.1158/1538-7445.Am2015-2891 |
0.408 |
|
| 2014 |
Tosti E, Katakowski JA, Schaetzlein S, Kim HS, Ryan CJ, Shales M, Roguev A, Krogan NJ, Palliser D, Keogh MC, Edelmann W. Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells. Genome Medicine. 6: 68. PMID 25302077 DOI: 10.1186/S13073-014-0068-4 |
0.497 |
|
| 2014 |
Woerner SM, Tosti E, Yuan YP, Kloor M, Bork P, Edelmann W, Gebert J. Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors. Molecular Carcinogenesis. PMID 25213383 DOI: 10.1002/Mc.22213 |
0.594 |
|
| 2014 |
Belcheva A, Irrazabal T, Robertson SJ, Streutker C, Maughan H, Rubino S, Moriyama EH, Copeland JK, Kumar S, Green B, Geddes K, Pezo RC, Navarre WW, Milosevic M, Wilson BC, ... ... Edelmann W, et al. Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells. Cell. 158: 288-99. PMID 25036629 DOI: 10.1016/J.Cell.2014.04.051 |
0.455 |
|
| 2014 |
Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, ... ... Edelmann W, et al. Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function. Cell Reports. 6: 892-905. PMID 24565511 DOI: 10.1016/J.Celrep.2014.01.029 |
0.336 |
|
| 2014 |
Dietlein F, Thelen L, Jokic M, Jachimowicz RD, Ivan L, Knittel G, Leeser U, van Oers J, Edelmann W, Heukamp LC, Reinhardt HC. A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC. Cancer Discovery. 4: 592-605. PMID 24556366 DOI: 10.1158/2159-8290.Cd-13-0907 |
0.544 |
|
| 2014 |
Zhang Y, Werling U, Edelmann W. Seamless Ligation Cloning Extract (SLiCE) cloning method. Methods in Molecular Biology (Clifton, N.J.). 1116: 235-44. PMID 24395368 DOI: 10.1007/978-1-62703-764-8_16 |
0.339 |
|
| 2014 |
van Oers JM, Edwards Y, Chahwan R, Zhang W, Smith C, Pechuan X, Schaetzlein S, Jin B, Wang Y, Bergman A, Scharff MD, Edelmann W. The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair. Oncogene. 33: 3939-46. PMID 24013230 DOI: 10.1038/Onc.2013.365 |
0.816 |
|
| 2014 |
Chen HJ, Sun J, Hou H, Edelmann W, Shen X, Lipkin SM. Abstract 3118: Chemokine-targeted colorectal cancer: improved models of human primary tumor formation, liver metastasis and chemoresistance Cancer Research. 74: 3118-3118. DOI: 10.1158/1538-7445.Am2014-3118 |
0.368 |
|
| 2013 |
Schaetzlein S, Chahwan R, Avdievich E, Roa S, Wei K, Eoff RL, Sellers RS, Clark AB, Kunkel TA, Scharff MD, Edelmann W. Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes. Proceedings of the National Academy of Sciences of the United States of America. 110: E2470-9. PMID 23754438 DOI: 10.1073/Pnas.1308512110 |
0.843 |
|
| 2013 |
Ene AC, Park S, Edelmann W, Taketo T. Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Developmental Biology. 377: 213-23. PMID 23384561 DOI: 10.1016/J.Ydbio.2013.01.027 |
0.317 |
|
| 2013 |
Bothmer A, Rommel PC, Gazumyan A, Polato F, Reczek CR, Muellenbeck MF, Schaetzlein S, Edelmann W, Chen PL, Brosh RM, Casellas R, Ludwig T, Baer R, Nussenzweig A, Nussenzweig MC, et al. Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching. The Journal of Experimental Medicine. 210: 115-23. PMID 23254285 DOI: 10.1084/Jem.20121975 |
0.461 |
|
| 2013 |
Kortüm B, Campregher C, Pinter M, Lang M, Evstatiev R, Khare V, Kucherlapati MH, Edelmann W, Gasche C. Abstract 176: Thymoquinone attenuates tumor development in a mouse model of Lynch syndrome. Cancer Research. 73: 176-176. DOI: 10.1158/1538-7445.Am2013-176 |
0.488 |
|
| 2013 |
Tosti E, Katakowski JA, Schaetzlein S, Kim H, Ryan CJ, Shales M, Roguev A, Krogan NJ, Palliser D, Keogh M, Edelmann W. Abstract A13: Identification of evolutionarily conserved genetic interactions in DNA mismatch repair Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A13 |
0.526 |
|
| 2013 |
Campregher C, Kortüm B, Pinter M, Lang M, Evstatiev R, Khare V, Kucherlapati MH, Edelmann W, Gasche C. 80 Mesalazine Decreases Microsatellite Instability and Tumor Development in the Villin-Cre Msh2loxp/Loxp Mouse Model of Lynch Syndrome Gastroenterology. 144: S-18. DOI: 10.1016/S0016-5085(13)60060-8 |
0.348 |
|
| 2012 |
Chen HJ, Edwards R, Tucci S, Bu P, Milsom J, Lee S, Edelmann W, Gümüs ZH, Shen X, Lipkin S. Chemokine 25-induced signaling suppresses colon cancer invasion and metastasis. The Journal of Clinical Investigation. 122: 3184-96. PMID 22863617 DOI: 10.1172/Jci62110 |
0.35 |
|
| 2012 |
Chahwan R, Edelmann W, Scharff MD, Roa S. AIDing antibody diversity by error-prone mismatch repair. Seminars in Immunology. 24: 293-300. PMID 22703640 DOI: 10.1016/J.Smim.2012.05.005 |
0.492 |
|
| 2012 |
Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, ... Edelmann W, et al. Hierarchical modularity and the evolution of genetic interactomes across species. Molecular Cell. 46: 691-704. PMID 22681890 DOI: 10.1016/J.Molcel.2012.05.028 |
0.324 |
|
| 2012 |
Chahwan R, van Oers JM, Avdievich E, Zhao C, Edelmann W, Scharff MD, Roa S. The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination. The Journal of Experimental Medicine. 209: 671-8. PMID 22451719 DOI: 10.1084/Jem.20111531 |
0.838 |
|
| 2012 |
Itano O, Fan K, Yang K, Suzuki K, Quimby F, Dong Z, Jin B, Edelmann W, Lipkin M. Effect of caloric intake on Western-style diet-induced intestinal tumors in a mouse model for hereditary colon cancer. Nutrition and Cancer. 64: 401-8. PMID 22439692 DOI: 10.1080/01635581.2012.660672 |
0.347 |
|
| 2012 |
Zhang Y, Werling U, Edelmann W. SLiCE: a novel bacterial cell extract-based DNA cloning method. Nucleic Acids Research. 40: e55. PMID 22241772 DOI: 10.1093/Nar/Gkr1288 |
0.345 |
|
| 2011 |
Chahwan R, Edelmann W, Scharff MD, Roa S. Mismatch-mediated error prone repair at the immunoglobulin genes. Biomedicine & Pharmacotherapy = Biomã©Decine & Pharmacothã©Rapie. 65: 529-36. PMID 22100214 DOI: 10.1016/J.Biopha.2011.09.001 |
0.482 |
|
| 2011 |
McIlhatton MA, Tyler J, Kerepesi LA, Bocker-Edmonston T, Kucherlapati MH, Edelmann W, Kucherlapati R, Kopelovich L, Fishel R. Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model. Cancer Prevention Research (Philadelphia, Pa.). 4: 684-93. PMID 21436383 DOI: 10.1158/1940-6207.Capr-10-0319 |
0.351 |
|
| 2010 |
Peled JU, Sellers RS, Iglesias-Ussel MD, Shin DM, Montagna C, Zhao C, Li Z, Edelmann W, Morse HC, Scharff MD. Msh6 protects mature B cells from lymphoma by preserving genomic stability. The American Journal of Pathology. 177: 2597-608. PMID 20934970 DOI: 10.2353/Ajpath.2010.100234 |
0.446 |
|
| 2010 |
Reiss C, Haneke T, Völker HU, Spahn M, Rosenwald A, Edelmann W, Kneitz B. Conditional inactivation of MLH1 in thymic and naive T-cells in mice leads to a limited incidence of lymphoblastic T-cell lymphomas. Leukemia & Lymphoma. 51: 1875-86. PMID 20858091 DOI: 10.3109/10428194.2010.510360 |
0.494 |
|
| 2010 |
Wang Y, Huang B, Edelmann L, Kolodner RD, Edelmann W. Genes essential for cell viability that are linked to tumor suppressor genes play a role in cancer susceptibility Cell Cycle. 9: 3144-3145. PMID 20703099 DOI: 10.4161/Cc.9.16.12956 |
0.477 |
|
| 2010 |
van Oers JM, Roa S, Werling U, Liu Y, Genschel J, Hou H, Sellers RS, Modrich P, Scharff MD, Edelmann W. PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance. Proceedings of the National Academy of Sciences of the United States of America. 107: 13384-9. PMID 20624957 DOI: 10.1073/Pnas.1008589107 |
0.562 |
|
| 2010 |
Roa S, Li Z, Peled JU, Zhao C, Edelmann W, Scharff MD. MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites. Plos One. 5: e11182. PMID 20567595 DOI: 10.1371/Journal.Pone.0011182 |
0.509 |
|
| 2010 |
Wang Y, Zhang W, Edelmann L, Kolodner RD, Kucherlapati R, Edelmann W. Cis lethal genetic interactions attenuate and alter p53 tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 5511-5. PMID 20212136 DOI: 10.1073/Pnas.1001223107 |
0.461 |
|
| 2010 |
Kucherlapati MH, Lee K, Nguyen AA, Clark AB, Hou H, Rosulek A, Li H, Yang K, Fan K, Lipkin M, Bronson RT, Jelicks L, Kunkel TA, Kucherlapati R, Edelmann W. An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents. Gastroenterology. 138: 993-1002.e1. PMID 19931261 DOI: 10.1053/J.Gastro.2009.11.009 |
0.654 |
|
| 2010 |
Huang B, Zhang W, Edelmann W, Wang Y. Abstract 2219: Identification of oncogenes in mutant Rpa1 associated tumorigenesis Cancer Research. 70: 2219-2219. DOI: 10.1158/1538-7445.Am10-2219 |
0.514 |
|
| 2009 |
Nepal RM, Tong L, Kolaj B, Edelmann W, Martin A. Msh2-dependent DNA repair mitigates a unique susceptibility of B cell progenitors to c-Myc-induced lymphomas. Proceedings of the National Academy of Sciences of the United States of America. 106: 18698-703. PMID 19837692 DOI: 10.1073/Pnas.0905965106 |
0.404 |
|
| 2009 |
Itano O, Yang K, Fan K, Kurihara N, Shinozaki H, Abe S, Jin B, Gravaghi C, Edelmann W, Augenlicht L, Kopelovich L, Kucherlapati R, Lamprecht S, Lipkin M. Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations. Carcinogenesis. 30: 1923-6. PMID 19755659 DOI: 10.1093/Carcin/Bgp200 |
0.529 |
|
| 2009 |
Tomé S, Holt I, Edelmann W, Morris GE, Munnich A, Pearson CE, Gourdon G. MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice. Plos Genetics. 5: e1000482. PMID 19436705 DOI: 10.1371/Journal.Pgen.1000482 |
0.552 |
|
| 2009 |
Kadyrov FA, Genschel J, Fang Y, Penland E, Edelmann W, Modrich P. A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair. Proceedings of the National Academy of Sciences of the United States of America. 106: 8495-500. PMID 19420220 DOI: 10.1073/Pnas.0903654106 |
0.485 |
|
| 2009 |
Bolderson E, Richard DJ, Edelmann W, Khanna KK. Involvement of Exo1b in DNA damage-induced apoptosis. Nucleic Acids Research. 37: 3452-63. PMID 19339515 DOI: 10.1093/nar/gkp194 |
0.314 |
|
| 2009 |
Taketo MM, Edelmann W. Mouse models of colon cancer. Gastroenterology. 136: 780-98. PMID 19263594 DOI: 10.1053/J.Gastro.2008.12.049 |
0.437 |
|
| 2009 |
Bolitho P, Street SE, Westwood JA, Edelmann W, Macgregor D, Waring P, Murray WK, Godfrey DI, Trapani JA, Johnstone RW, Smyth MJ. Perforin-mediated suppression of B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 106: 2723-8. PMID 19196996 DOI: 10.1073/Pnas.0809008106 |
0.316 |
|
| 2009 |
Klapacz J, Meira LB, Luchetti DG, Calvo JA, Bronson RT, Edelmann W, Samson LD. O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 576-81. PMID 19124772 DOI: 10.1073/Pnas.0811991106 |
0.432 |
|
| 2009 |
Dragileva E, Hendricks A, Teed A, Gillis T, Lopez ET, Friedberg EC, Kucherlapati R, Edelmann W, Lunetta KL, MacDonald ME, Wheeler VC. Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes. Neurobiology of Disease. 33: 37-47. PMID 18930147 DOI: 10.1016/J.Nbd.2008.09.014 |
0.412 |
|
| 2009 |
Eude-Le Parco I, Gendronneau G, Dang T, Delacour D, Thijssen VL, Edelmann W, Peuchmaur M, Poirier F. Genetic assessment of the importance of galectin-3 in cancer initiation, progression, and dissemination in mice. Glycobiology. 19: 68-75. PMID 18849326 DOI: 10.1093/Glycob/Cwn105 |
0.455 |
|
| 2008 |
Guikema JE, Schrader CE, Leus NG, Ucher A, Linehan EK, Werling U, Edelmann W, Stavnezer J. Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching. Journal of Immunology (Baltimore, Md. : 1950). 181: 8450-9. PMID 19050263 DOI: 10.4049/Jimmunol.181.12.8450 |
0.367 |
|
| 2008 |
Roa S, Avdievich E, Peled JU, Maccarthy T, Werling U, Kuang FL, Kan R, Zhao C, Bergman A, Cohen PE, Edelmann W, Scharff MD. Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression. Proceedings of the National Academy of Sciences of the United States of America. 105: 16248-53. PMID 18854411 DOI: 10.1073/Pnas.0808182105 |
0.831 |
|
| 2008 |
Yang K, Kurihara N, Fan K, Newmark H, Rigas B, Bancroft L, Corner G, Livote E, Lesser M, Edelmann W, Velcich A, Lipkin M, Augenlicht L. Dietary induction of colonic tumors in a mouse model of sporadic colon cancer. Cancer Research. 68: 7803-10. PMID 18829535 DOI: 10.1158/0008-5472.Can-08-1209 |
0.411 |
|
| 2008 |
Yang K, Popova NV, Yang WC, Lozonschi I, Tadesse S, Kent S, Bancroft L, Matise I, Cormier RT, Scherer SJ, Edelmann W, Lipkin M, Augenlicht L, Velcich A. Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation. Cancer Research. 68: 7313-22. PMID 18794118 DOI: 10.1158/0008-5472.Can-08-0598 |
0.54 |
|
| 2008 |
Holloway JK, Booth J, Edelmann W, McGowan CH, Cohen PE. MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis. Plos Genetics. 4: e1000186. PMID 18787696 DOI: 10.1371/Journal.Pgen.1000186 |
0.52 |
|
| 2008 |
Marinovic-Terzic I, Yoshioka-Yamashita A, Shimodaira H, Avdievich E, Hunton IC, Kolodner RD, Edelmann W, Wang JYJ. Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q Proceedings of the National Academy of Sciences of the United States of America. 105: 13993-13998. PMID 18768816 DOI: 10.1073/Pnas.0806435105 |
0.801 |
|
| 2008 |
Gravaghi C, Bo J, Laperle KM, Quimby F, Kucherlapati R, Edelmann W, Lamprecht SA. Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice. International Journal of Obesity (2005). 32: 1716-9. PMID 18725892 DOI: 10.1038/Ijo.2008.149 |
0.422 |
|
| 2008 |
Yang K, Lamprecht SA, Shinozaki H, Fan K, Yang W, Newmark HL, Kopelovich L, Edelmann W, Jin B, Gravaghi C, Augenlicht L, Kucherlapati R, Lipkin M. Dietary calcium and cholecalciferol modulate cyclin D1 expression, apoptosis, and tumorigenesis in intestine of adenomatous polyposis coli1638N/+ mice. The Journal of Nutrition. 138: 1658-63. PMID 18716166 DOI: 10.1093/Jn/138.9.1658 |
0.424 |
|
| 2008 |
Chen PC, Kuraguchi M, Velasquez J, Wang Y, Yang K, Edwards R, Gillen D, Edelmann W, Kucherlapati R, Lipkin SM. Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression. Plos Genetics. 4: e1000092. PMID 18551179 DOI: 10.1371/Journal.Pgen.1000092 |
0.548 |
|
| 2008 |
Morelli MA, Werling U, Edelmann W, Roberson MS, Cohen PE. Analysis of meiotic prophase I in live mouse spermatocytes. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 16: 743-60. PMID 18516692 DOI: 10.1007/S10577-008-1224-8 |
0.324 |
|
| 2008 |
Avdievich E, Reiss C, Scherer SJ, Zhang Y, Maier SM, Jin B, Hou H, Rosenwald A, Riedmiller H, Kucherlapati R, Cohen PE, Edelmann W, Kneitz B. Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4247-52. PMID 18337503 DOI: 10.1073/Pnas.0800276105 |
0.861 |
|
| 2008 |
Kan R, Sun X, Kolas NK, Avdievich E, Kneitz B, Edelmann W, Cohen PE. Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway. Biology of Reproduction. 78: 462-71. PMID 18057311 DOI: 10.1095/Biolreprod.107.065771 |
0.836 |
|
| 2007 |
Palmerini E, Fan K, Yang K, Risio M, Edelmann W, Lipkin M, Biasco G. Piroxicam increases colon tumorigenesis and promotes apoptosis in Mlh1 +/- /Apc1638(N/+) mice. Anticancer Research. 27: 3807-12. PMID 18225536 |
0.308 |
|
| 2007 |
Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepczynska A, Lilli DR, Clark AB, Rudolph C, Kuhnel F, Wei K, Schlegelberger B, Schirmacher P, Kunkel TA, Greenberg RA, Edelmann W, et al. Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice. Cell. 130: 863-77. PMID 17803909 DOI: 10.1016/J.Cell.2007.08.029 |
0.526 |
|
| 2007 |
Kucherlapati M, Nguyen A, Kuraguchi M, Yang K, Fan K, Bronson R, Wei K, Lipkin M, Edelmann W, Kucherlapati R. Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies. Oncogene. 26: 6297-306. PMID 17452984 DOI: 10.1038/Sj.Onc.1210453 |
0.491 |
|
| 2006 |
Wang JY, Edelmann W. Mismatch repair proteins as sensors of alkylation DNA damage. Cancer Cell. 9: 417-8. PMID 16766259 DOI: 10.1016/J.Ccr.2006.05.013 |
0.475 |
|
| 2006 |
Hegan DC, Narayanan L, Jirik FR, Edelmann W, Liskay RM, Glazer PM. Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6. Carcinogenesis. 27: 2402-8. PMID 16728433 DOI: 10.1093/Carcin/Bgl079 |
0.568 |
|
| 2006 |
Li Z, Zhao C, Iglesias-Ussel MD, Polonskaya Z, Zhuang M, Yang G, Luo Z, Edelmann W, Scharff MD. The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus. Immunity. 24: 393-403. PMID 16618598 DOI: 10.1016/J.Immuni.2006.02.011 |
0.404 |
|
| 2006 |
Arnold JS, Werling U, Braunstein EM, Liao J, Nowotschin S, Edelmann W, Hebert JM, Morrow BE. Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations. Development (Cambridge, England). 133: 977-87. PMID 16452092 DOI: 10.1242/Dev.02264 |
0.429 |
|
| 2005 |
Larijani M, Zaheen A, Frieder D, Wang Y, Wu GE, Edelmann W, Martin A. Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining events. Nucleic Acids Research. 33: 6733-42. PMID 16314305 DOI: 10.1093/Nar/Gki983 |
0.419 |
|
| 2005 |
Kolas NK, Svetlanov A, Lenzi ML, Macaluso FP, Lipkin SM, Liskay RM, Greally J, Edelmann W, Cohen PE. Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I. The Journal of Cell Biology. 171: 447-58. PMID 16260499 DOI: 10.1083/Jcb.200506170 |
0.552 |
|
| 2005 |
Zervas M, Opitz T, Edelmann W, Wainer B, Kucherlapati R, Stanton PK. Impaired hippocampal long-term potentiation in microtubule-associated protein 1B-deficient mice. Journal of Neuroscience Research. 82: 83-92. PMID 16118800 DOI: 10.1002/Jnr.20624 |
0.344 |
|
| 2005 |
Scherer SJ, Avdievich E, Edelmann W. Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition. Biochemical Society Transactions. 33: 689-93. PMID 16042575 DOI: 10.1042/Bst0330689 |
0.838 |
|
| 2005 |
Owen BA, Yang Z, Lai M, Gajec M, Gajek M, Badger JD, Hayes JJ, Edelmann W, Kucherlapati R, Wilson TM, McMurray CT. (CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition. Nature Structural & Molecular Biology. 12: 663-70. PMID 16025128 DOI: 10.1038/Nsmb965 |
0.454 |
|
| 2005 |
Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, Edelmann W. Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice. Nature Genetics. 37: 750-5. PMID 15965476 DOI: 10.1038/Ng1587 |
0.581 |
|
| 2005 |
Yang K, Fan KH, Lamprecht SA, Edelmann W, Kopelovich L, Kucherlapati R, Lipkin M. Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice. International Journal of Cancer. Journal International Du Cancer. 116: 495-9. PMID 15818612 DOI: 10.1002/Ijc.21018 |
0.514 |
|
| 2005 |
Di Giacomo M, Barchi M, Baudat F, Edelmann W, Keeney S, Jasin M. Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. Proceedings of the National Academy of Sciences of the United States of America. 102: 737-42. PMID 15640358 DOI: 10.1073/Pnas.0406212102 |
0.529 |
|
| 2004 |
Yang G, Scherer SJ, Shell SS, Yang K, Kim M, Lipkin M, Kucherlapati R, Kolodner RD, Edelmann W. Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. Cancer Cell. 6: 139-50. PMID 15324697 DOI: 10.1016/J.Ccr.2004.06.024 |
0.603 |
|
| 2004 |
Edelmann L, Edelmann W. Loss of DNA mismatch repair function and cancer predisposition in the mouse: animal models for human hereditary nonpolyposis colorectal cancer. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 129: 91-9. PMID 15264277 DOI: 10.1002/Ajmg.C.30021 |
0.547 |
|
| 2004 |
Li Z, Scherer SJ, Ronai D, Iglesias-Ussel MD, Peled JU, Bardwell PD, Zhuang M, Lee K, Martin A, Edelmann W, Scharff MD. Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification. The Journal of Experimental Medicine. 200: 47-59. PMID 15238604 DOI: 10.1084/Jem.20040355 |
0.603 |
|
| 2004 |
Lin DP, Wang Y, Scherer SJ, Clark AB, Yang K, Avdievich E, Jin B, Werling U, Parris T, Kurihara N, Umar A, Kucherlapati R, Lipkin M, Kunkel TA, Edelmann W. An Msh2 point mutation uncouples DNA mismatch repair and apoptosis. Cancer Research. 64: 517-22. PMID 14744764 DOI: 10.1158/0008-5472.Can-03-2957 |
0.816 |
|
| 2004 |
Bardwell PD, Woo CJ, Wei K, Li Z, Martin A, Sack SZ, Parris T, Edelmann W, Scharff MD. Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. Nature Immunology. 5: 224-9. PMID 14716311 DOI: 10.1038/Ni1031 |
0.827 |
|
| 2003 |
Kabbarah O, Mallon MA, Pfeifer JD, Edelmann W, Kucherlapati R, Goodfellow PJ. A panel of repeat markers for detection of microsatellite instability in murine tumors. Molecular Carcinogenesis. 38: 155-9. PMID 14639654 DOI: 10.1002/Mc.10157 |
0.52 |
|
| 2003 |
Young LC, Peters AC, Maeda T, Edelmann W, Kucherlapati R, Andrew SE, Tron VA. DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts. The Journal of Investigative Dermatology. 121: 876-80. PMID 14632208 DOI: 10.1046/J.1523-1747.2003.12486.X |
0.503 |
|
| 2003 |
Pretlow TP, Edelmann W, Kucherlapati R, Pretlow TG, Augenlicht LH. Spontaneous aberrant crypt foci in Apc1638N mice with a mutant Apc allele. The American Journal of Pathology. 163: 1757-63. PMID 14578176 DOI: 10.1016/S0002-9440(10)63535-3 |
0.529 |
|
| 2003 |
Martin A, Li Z, Lin DP, Bardwell PD, Iglesias-Ussel MD, Edelmann W, Scharff MD. Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination. The Journal of Experimental Medicine. 198: 1171-8. PMID 14568978 DOI: 10.1084/Jem.20030880 |
0.574 |
|
| 2003 |
Yang K, Fan K, Kurihara N, Shinozaki H, Rigas B, Augenlicht L, Kopelovich L, Edelmann W, Kucherlapati R, Lipkin M. Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations. Carcinogenesis. 24: 605-11. PMID 12663524 DOI: 10.1093/Carcin/24.3.605 |
0.474 |
|
| 2003 |
Wei K, Clark AB, Wong E, Kane MF, Mazur DJ, Parris T, Kolas NK, Russell R, Hou H, Kneitz B, Yang G, Kunkel TA, Kolodner RD, Cohen PE, Edelmann W. Inactivation of exonuclease I in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility Genes and Development. 17: 603-614. PMID 12629043 DOI: 10.1101/Gad.1060603 |
0.813 |
|
| 2003 |
Bardwell PD, Martin A, Wong E, Li Z, Edelmann W, Scharff MD. Cutting edge: the G-U mismatch glycosylase methyl-CpG binding domain 4 is dispensable for somatic hypermutation and class switch recombination. Journal of Immunology (Baltimore, Md. : 1950). 170: 1620-4. PMID 12574322 DOI: 10.4049/Jimmunol.170.4.1620 |
0.736 |
|
| 2002 |
Wong E, Yang K, Kuraguchi M, Werling U, Avdievich E, Fan K, Fazzari M, Jin B, Brown AM, Lipkin M, Edelmann W. Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 14937-42. PMID 12417741 DOI: 10.1073/Pnas.232579299 |
0.83 |
|
| 2002 |
Mark SC, Sandercock LE, Luchman HA, Baross A, Edelmann W, Jirik FR. Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium. Oncogene. 21: 7126-30. PMID 12370835 DOI: 10.1038/Sj.Onc.1205861 |
0.52 |
|
| 2002 |
Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, Kucherlapati R, Gonzalez FJ, Spiegelman BM. APC-dependent suppression of colon carcinogenesis by PPARgamma. Proceedings of the National Academy of Sciences of the United States of America. 99: 13771-6. PMID 12370429 DOI: 10.1073/Pnas.162480299 |
0.407 |
|
| 2002 |
Wu G, Tian X, Nishimura S, Markowitz GS, D'Agati V, Park JH, Yao L, Li L, Geng L, Zhao H, Edelmann W, Somlo S. Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease. Human Molecular Genetics. 11: 1845-54. PMID 12140187 DOI: 10.1093/Hmg/11.16.1845 |
0.44 |
|
| 2002 |
Kucherlapati M, Yang K, Kuraguchi M, Zhao J, Lia M, Heyer J, Kane MF, Fan K, Russell R, Brown AM, Kneitz B, Edelmann W, Kolodner RD, Lipkin M, Kucherlapati R. Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 99: 9924-9. PMID 12119409 DOI: 10.1073/Pnas.152321699 |
0.584 |
|
| 2002 |
Wei K, Kucherlapati R, Edelmann W. Mouse models for human DNA mismatch-repair gene defects. Trends in Molecular Medicine. 8: 346-53. PMID 12114115 DOI: 10.1016/S1471-4914(02)02359-6 |
0.545 |
|
| 2002 |
Wang H, Douglas W, Lia M, Edelmann W, Kucherlapati R, Podsypanina K, Parsons R, Ellenson LH. DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice. The American Journal of Pathology. 160: 1481-6. PMID 11943731 DOI: 10.1016/S0002-9440(10)62573-4 |
0.568 |
|
| 2002 |
Razani B, Wang XB, Engelman JA, Battista M, Lagaud G, Zhang XL, Kneitz B, Hou H, Christ GJ, Edelmann W, Lisanti MP. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Molecular and Cellular Biology. 22: 2329-44. PMID 11884617 DOI: 10.1128/Mcb.22.7.2329-2344.2002 |
0.442 |
|
| 2002 |
Lan Z, Sever-Chroneos Z, Strobeck MW, Park CH, Baskaran R, Edelmann W, Leone G, Knudsen ES. DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. The Journal of Biological Chemistry. 277: 8372-81. PMID 11726663 DOI: 10.1074/Jbc.M108906200 |
0.439 |
|
| 2001 |
Kuraguchi M, Yang K, Wong E, Avdievich E, Fan K, Kolodner RD, Lipkin M, Brown AM, Kucherlapati R, Edelmann W. The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Research. 61: 7934-42. PMID 11691815 |
0.84 |
|
| 2001 |
Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H, Kneitz B, Lagaud G, Christ GJ, ... Edelmann W, et al. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. The Journal of Biological Chemistry. 276: 38121-38. PMID 11457855 DOI: 10.1074/Jbc.M105408200 |
0.419 |
|
| 2001 |
Kucherlapati R, Lin DP, Edelmann W. Mouse models for human familial adenomatous polyposis. Seminars in Cancer Biology. 11: 219-25. PMID 11407946 DOI: 10.1006/Scbi.2001.0368 |
0.329 |
|
| 2001 |
Zhao R, Russell RG, Wang Y, Liu L, Gao F, Kneitz B, Edelmann W, Goldman ID. Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs. The Journal of Biological Chemistry. 276: 10224-8. PMID 11266438 DOI: 10.1074/Jbc.C000905200 |
0.37 |
|
| 2001 |
Galbiati F, Engelman JA, Volonte D, Zhang XL, Minetti C, Li M, Hou H, Kneitz B, Edelmann W, Lisanti MP. Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities. The Journal of Biological Chemistry. 276: 21425-33. PMID 11259414 DOI: 10.1074/Jbc.M100828200 |
0.419 |
|
| 2000 |
Kuraguchi M, Edelmann W, Yang K, Lipkin M, Kucherlapati R, Brown AM. Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency. Oncogene. 19: 5755-63. PMID 11126362 DOI: 10.1038/Sj.Onc.1203962 |
0.538 |
|
| 2000 |
Smits R, Hofland N, Edelmann W, Geugien M, Jagmohan-Changur S, Albuquerque C, Breukel C, Kucherlapati R, Kielman MF, Fodde R. Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity. Genes, Chromosomes & Cancer. 29: 229-39. PMID 10992298 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1033>3.0.Co;2-R |
0.416 |
|
| 2000 |
Kneitz B, Cohen PE, Avdievich E, Zhu L, Kane MF, Hou H, Kolodner RD, Kucherlapati R, Pollard JW, Edelmann W. MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes & Development. 14: 1085-97. PMID 10809667 DOI: 10.1101/Gad.14.9.1085 |
0.787 |
|
| 2000 |
Edelmann W, Umar A, Yang K, Heyer J, Kucherlapati M, Lia M, Kneitz B, Avdievich E, Fan K, Wong E, Crouse G, Kunkel T, Lipkin M, Kolodner RD, Kucherlapati R. The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Research. 60: 803-7. PMID 10706084 |
0.849 |
|
| 2000 |
Wiesendanger M, Kneitz B, Edelmann W, Scharff MD. Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern. The Journal of Experimental Medicine. 191: 579-84. PMID 10662804 DOI: 10.1084/Jem.191.3.579 |
0.551 |
|
| 2000 |
Wu G, Markowitz GS, Li L, D'Agati VD, Factor SM, Geng L, Tibara S, Tuchman J, Cai Y, Park JH, van Adelsberg J, Hou H, Kucherlapati R, Edelmann W, Somlo S. Cardiac defects and renal failure in mice with targeted mutations in Pkd2. Nature Genetics. 24: 75-8. PMID 10615132 DOI: 10.1038/71724 |
0.474 |
|
| 1999 |
Lipkin M, Yang K, Edelmann W, Xue L, Fan K, Risio M, Newmark H, Kucherlapati R. Preclinical mouse models for cancer chemoprevention studies. Annals of the New York Academy of Sciences. 889: 14-9. PMID 10668478 DOI: 10.1111/J.1749-6632.1999.Tb08719.X |
0.383 |
|
| 1999 |
Heyer J, Escalante-Alcalde D, Lia M, Boettinger E, Edelmann W, Stewart CL, Kucherlapati R. Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 96: 12595-600. PMID 10535967 DOI: 10.1073/Pnas.96.22.12595 |
0.361 |
|
| 1999 |
Heyer J, Yang K, Lipkin M, Edelmann W, Kucherlapati R. Mouse models for colorectal cancer. Oncogene. 18: 5325-33. PMID 10498885 DOI: 10.1038/Sj.Onc.1203036 |
0.571 |
|
| 1999 |
Schrader CE, Edelmann W, Kucherlapati R, Stavnezer J. Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes. The Journal of Experimental Medicine. 190: 323-30. PMID 10430621 DOI: 10.1084/Jem.190.3.323 |
0.419 |
|
| 1999 |
Smits R, Kielman MF, Breukel C, Zurcher C, Neufeld K, Jagmohan-Changur S, Hofland N, van Dijk J, White R, Edelmann W, Kucherlapati R, Khan PM, Fodde R. Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development. Genes & Development. 13: 1309-21. PMID 10346819 DOI: 10.1101/Gad.13.10.1309 |
0.461 |
|
| 1999 |
Edelmann W, Cohen PE, Kneitz B, Winand N, Lia M, Heyer J, Kolodner R, Pollard JW, Kucherlapati R. Mammalian MutS homologue 5 is required for chromosome pairing in meiosis. Nature Genetics. 21: 123-7. PMID 9916805 DOI: 10.1038/5075 |
0.605 |
|
| 1998 |
Wiesendanger M, Scharff MD, Edelmann W. Somatic hypermutation, transcription, and DNA mismatch repair. Cell. 94: 415-8. PMID 9727483 DOI: 10.1016/S0092-8674(00)81581-0 |
0.43 |
|
| 1998 |
Ness SL, Edelmann W, Jenkins TD, Liedtke W, Rustgi AK, Kucherlapati R. Mouse keratin 4 is necessary for internal epithelial integrity. The Journal of Biological Chemistry. 273: 23904-11. PMID 9727004 DOI: 10.1074/Jbc.273.37.23904 |
0.397 |
|
| 1998 |
Wu G, D'Agati V, Cai Y, Markowitz G, Park JH, Reynolds DM, Maeda Y, Le TC, Hou H, Kucherlapati R, Edelmann W, Somlo S. Somatic inactivation of Pkd2 results in polycystic kidney disease. Cell. 93: 177-88. PMID 9568711 DOI: 10.1016/S0092-8674(00)81570-6 |
0.425 |
|
| 1998 |
Liedtke W, Edelmann W. Lymphomatous leptomeningitis in mice lacking the DNA mismatch repair gene Msh6 Journal of Neuroimmunology. 90: 101. DOI: 10.1016/S0165-5728(98)91783-0 |
0.455 |
|
| 1997 |
Edelmann W, Yang K, Umar A, Heyer J, Lau K, Fan K, Liedtke W, Cohen PE, Kane MF, Lipford JR, Yu N, Crouse GF, Pollard JW, Kunkel T, Lipkin M, et al. Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. Cell. 91: 467-77. PMID 9390556 DOI: 10.1016/S0092-8674(00)80433-X |
0.592 |
|
| 1997 |
Acakpo-Satchivi LJ, Edelmann W, Sartorius C, Lu BD, Wahr PA, Watkins SC, Metzger JM, Leinwand L, Kucherlapati R. Growth and muscle defects in mice lacking adult myosin heavy chain genes. The Journal of Cell Biology. 139: 1219-29. PMID 9382868 DOI: 10.1083/Jcb.139.5.1219 |
0.366 |
|
| 1997 |
Marcus DM, Rustgi AK, Defoe D, Brooks SE, McCormick RS, Thompson TP, Edelmann W, Kucherlapati R, Smith S. Retinal pigment epithelium abnormalities in mice with adenomatous polyposis coli gene disruption. Archives of Ophthalmology (Chicago, Ill. : 1960). 115: 645-50. PMID 9152133 DOI: 10.1001/Archopht.1997.01100150647013 |
0.377 |
|
| 1997 |
Yang K, Edelmann W, Fan K, Lau K, Kolli VR, Fodde R, Khan PM, Kucherlapati R, Lipkin M. A mouse model of human familial adenomatous polyposis. The Journal of Experimental Zoology. 277: 245-54. PMID 9062998 DOI: 10.1002/(Sici)1097-010X(19970215)277:3<245::Aid-Jez5>3.0.Co;2-O |
0.539 |
|
| 1997 |
Smits R, Kartheuser A, Jagmohan-Changur S, Leblanc V, Breukel C, de Vries A, van Kranen H, van Krieken JH, Williamson S, Edelmann W, Kucherlapati R, KhanPM, Fodde R. Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis. 18: 321-7. PMID 9054624 DOI: 10.1093/Carcin/18.2.321 |
0.498 |
|
| 1996 |
Lipkin M, Yang K, Edelmann W, Newmark H, Fan KH, Risio M, Kucherlapati R. Inherited and acquired risk factors in colonic neoplasia and modulation by chemopreventive interventions. Journal of Cellular Biochemistry. Supplement. 25: 136-41. PMID 9027610 DOI: 10.1002/(Sici)1097-4644(1996)25+<136::Aid-Jcb19>3.0.Co;2-M |
0.461 |
|
| 1996 |
Liedtke W, Edelmann W, Bieri PL, Chiu FC, Cowan NJ, Kucherlapati R, Raine CS. GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron. 17: 607-15. PMID 8893019 DOI: 10.1016/S0896-6273(00)80194-4 |
0.32 |
|
| 1996 |
Edelmann W, Kucherlapati R. Role of recombination enzymes in mammalian cell survival. Proceedings of the National Academy of Sciences of the United States of America. 93: 6225-7. PMID 8692795 DOI: 10.1073/Pnas.93.13.6225 |
0.5 |
|
| 1996 |
Edelmann W, Cohen PE, Kane M, Lau K, Morrow B, Bennett S, Umar A, Kunkel T, Cattoretti G, Chaganti R, Pollard JW, Kolodner RD, Kucherlapati R. Meiotic pachytene arrest in MLH1-deficient mice. Cell. 85: 1125-34. PMID 8674118 DOI: 10.1016/S0092-8674(00)81312-4 |
0.596 |
|
| 1996 |
Schubart UK, Yu J, Amat JA, Wang Z, Hoffmann MK, Edelmann W. Normal development of mice lacking metablastin (P19), a phosphoprotein implicated in cell cycle regulation. The Journal of Biological Chemistry. 271: 14062-6. PMID 8662897 DOI: 10.1074/Jbc.271.24.14062 |
0.45 |
|
| 1996 |
Edelmann W, Zervas M, Costello P, Roback L, Fischer I, Hammarback JA, Cowan N, Davies P, Wainer B, Kucherlapati R. Neuronal abnormalities in microtubule-associated protein 1B mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 1270-5. PMID 8577753 DOI: 10.1073/Pnas.93.3.1270 |
0.392 |
|
| 1996 |
Liedtke W, Edelmann W, Kucherlapati R, Raine CS. THE NEUROPATHOLOGIC PHENOTYPE OF GFAP DEFICIENT MICE Journal of Neuropathology and Experimental Neurology. 55: 620. DOI: 10.1097/00005072-199605000-00071 |
0.341 |
|
| 1995 |
Umanoff H, Edelmann W, Pellicer A, Kucherlapati R. The murine N-ras gene is not essential for growth and development. Proceedings of the National Academy of Sciences of the United States of America. 92: 1709-13. PMID 7878045 DOI: 10.1073/Pnas.92.5.1709 |
0.353 |
|
| 1995 |
Sirotkin AM, Edelmann W, Cheng G, Klein-Szanto A, Kucherlapati R, Skoultchi AI. Mice develop normally without the H1(0) linker histone. Proceedings of the National Academy of Sciences of the United States of America. 92: 6434-8. PMID 7604008 DOI: 10.1073/Pnas.92.14.6434 |
0.326 |
|
| 1994 |
Fodde R, Edelmann W, Yang K, Van Leeuwen C, Carlson C, Renault B, Breukel C, Alt E, Lipkin M, Khan PM, Kucherlapati R. A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors Proceedings of the National Academy of Sciences of the United States of America. 91: 8969-8973. PMID 8090754 DOI: 10.1073/Pnas.91.19.8969 |
0.51 |
|
| 1989 |
Edelmann W, Kröger B, Goller M, Horak I. A recombination hotspot in the LTR of a mouse retrotransposon identified in an in vitro system. Cell. 57: 937-46. PMID 2544295 DOI: 10.1016/0092-8674(89)90332-2 |
0.405 |
|
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