| Year |
Citation |
Score |
| 2023 |
Chen ST, Oliveira TY, Gazumyan A, Cipolla M, Nussenzweig MC. B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection. Immunity. 56: 547-561.e7. PMID 36882061 DOI: 10.1016/j.immuni.2023.02.003 |
0.316 |
|
| 2023 |
Gristick HB, Hartweger H, Loewe M, van Schooten J, Ramos V, Oliveira TY, Nishimura Y, Koranda NS, Wall A, Yao KH, Poston D, Gazumyan A, Wiatr M, Horning M, Keeffe JR, ... ... Nussenzweig MC, et al. CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals. Science Immunology. 8: eade6364. PMID 36763635 DOI: 10.1126/sciimmunol.ade6364 |
0.312 |
|
| 2022 |
Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, ... ... Nussenzweig MC, et al. HIV-1 Vpu restricts Fc-mediated effector functions in vivo. Cell Reports. 41: 111624. PMID 36351384 DOI: 10.1016/j.celrep.2022.111624 |
0.311 |
|
| 2022 |
Rosás-Umbert M, Gunst JD, Pahus MH, Olesen R, Schleimann M, Denton PW, Ramos V, Ward A, Kinloch NN, Copertino DC, Escribà T, Llano A, Brumme ZL, Brad Jones R, Mothe B, ... ... Nussenzweig MC, et al. Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8 T cell immunity. Nature Communications. 13: 6473. PMID 36309514 DOI: 10.1038/s41467-022-34171-2 |
0.312 |
|
| 2021 |
Viant C, Escolano A, Chen ST, Nussenzweig MC. Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells. Star Protocols. 2: 100389. PMID 33778783 DOI: 10.1016/j.xpro.2021.100389 |
0.324 |
|
| 2020 |
Zhou Y, Liu Z, Wang Z, Zhang Q, Mayer CT, Schoofs T, Nussenzweig MC, de Jong YP, Wang Q. Single-Cell Sorting of HBsAg-Binding Memory B Cells from Human Peripheral Blood Mononuclear Cells and Antibody Cloning. Star Protocols. 1: 100129. PMID 33377023 DOI: 10.1016/j.xpro.2020.100129 |
0.316 |
|
| 2020 |
Viant C, Weymar GHJ, Escolano A, Chen S, Hartweger H, Cipolla M, Gazumyan A, Nussenzweig MC. Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates. Cell. PMID 33125897 DOI: 10.1016/j.cell.2020.09.063 |
0.303 |
|
| 2020 |
Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M, Alcami J, Hazuda D, Bushman F, Siliciano JD, Betts MR, et al. Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nature Medicine. PMID 32895573 DOI: 10.1038/S41591-020-1022-1 |
0.318 |
|
| 2020 |
Sharma VK, Misra B, McManus KT, Avula S, Nellaiappan K, Caskey M, Horowitz J, Nussenzweig MC, Seaman MS, Javeri I, Dey AK. Characterization of Co-Formulated High-Concentration Broadly Neutralizing Anti-HIV-1 Monoclonal Antibodies for Subcutaneous Administration. Antibodies (Basel, Switzerland). 9. PMID 32751063 DOI: 10.3390/Antib9030036 |
0.385 |
|
| 2020 |
Schmidt F, Weisblum Y, Muecksch F, Hoffmann HH, Michailidis E, Lorenzi JCC, Mendoza P, Rutkowska M, Bednarski E, Gaebler C, Agudelo M, Cho A, Wang Z, Gazumyan A, Cipolla M, ... ... Nussenzweig MC, et al. Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses. The Journal of Experimental Medicine. 217. PMID 32692348 DOI: 10.1084/Jem.20201181 |
0.352 |
|
| 2020 |
Hoffmann MAG, Bar-On Y, Yang Z, Gristick HB, Gnanapragasam PNP, Vielmetter J, Nussenzweig MC, Bjorkman PJ. Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690692 DOI: 10.1073/Pnas.2010320117 |
0.324 |
|
| 2020 |
Barnes CO, West AP, Huey-Tubman KE, Hoffmann MAG, Sharaf NG, Hoffman PR, Koranda N, Gristick HB, Gaebler C, Muecksch F, Lorenzi JCC, Finkin S, Hägglöf T, Hurley A, Millard KG, ... ... Nussenzweig MC, et al. Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell. PMID 32645326 DOI: 10.1016/J.Cell.2020.06.025 |
0.362 |
|
| 2020 |
Garber DA, Adams DR, Guenthner P, Mitchell J, Kelley K, Schoofs T, Gazumyan A, Nason M, Seaman MS, McNicholl J, Nussenzweig MC, Heneine W. Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies. Nature Communications. 11: 3195. PMID 32581216 DOI: 10.1038/S41467-020-16928-9 |
0.333 |
|
| 2020 |
Robbiani DF, Gaebler C, Muecksch F, Lorenzi JCC, Wang Z, Cho A, Agudelo M, Barnes CO, Gazumyan A, Finkin S, Hägglöf T, Oliveira TY, Viant C, Hurley A, Hoffmann HH, ... ... Nussenzweig MC, et al. Convergent antibody responses to SARS-CoV-2 in convalescent individuals. Nature. PMID 32555388 DOI: 10.1038/S41586-020-2456-9 |
0.391 |
|
| 2020 |
Wang Q, Michailidis E, Yu Y, Wang Z, Hurley AM, Oren DA, Mayer CT, Gazumyan A, Liu Z, Zhou Y, Schoofs T, Yao KH, Nieke JP, Wu J, Jiang Q, ... ... Nussenzweig MC, et al. A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations. Cell Host & Microbe. PMID 32504577 DOI: 10.1016/J.Chom.2020.05.010 |
0.353 |
|
| 2020 |
Esswein SR, Gristick HB, Jurado A, Peace A, Keeffe JR, Lee YE, Voll AV, Saeed M, Nussenzweig MC, Rice CM, Robbiani DF, MacDonald MR, Bjorkman PJ. Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America. PMID 32321830 DOI: 10.1073/Pnas.1919269117 |
0.317 |
|
| 2020 |
Mendoza P, Jackson JR, Oliveira TY, Gaebler C, Ramos V, Caskey M, Jankovic M, Nussenzweig MC, Cohn LB. Antigen-responsive CD4+ T cell clones contribute to the HIV-1 latent reservoir. The Journal of Experimental Medicine. 217. PMID 32311008 DOI: 10.1084/Jem.20200051 |
0.397 |
|
| 2020 |
Van Rompay KKA, Coffey LL, Kapoor T, Gazumyan A, Keesler RI, Jurado A, Peace A, Agudelo M, Watanabe J, Usachenko J, Singapuri A, Immareddy R, Ardeshir A, Stuart JB, Bournazos S, ... ... Nussenzweig MC, et al. A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques. Proceedings of the National Academy of Sciences of the United States of America. PMID 32209664 DOI: 10.1073/Pnas.2000414117 |
0.354 |
|
| 2020 |
Niessl J, Baxter AE, Mendoza P, Jankovic M, Cohen YZ, Butler AL, Lu CL, Dubé M, Shimeliovich I, Gruell H, Klein F, Caskey M, Nussenzweig MC, Kaufmann DE. Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity. Nature Medicine. PMID 32015556 DOI: 10.1038/S41591-019-0747-1 |
0.409 |
|
| 2019 |
Wang Z, Merkenschlager J, Chen ST, Oliveira TY, Ramos V, Gordon KM, Yao KH, Jankovic M, Gazumyan A, Nussenzweig M, Escolano A. Isolation of single HIV-1 Envelope specific B cells and antibody cloning from immunized rhesus macaques. Journal of Immunological Methods. 112734. PMID 31866284 DOI: 10.1016/J.Jim.2019.112734 |
0.458 |
|
| 2019 |
Ringe RP, Cruz Portillo VM, Dosenovic P, Ketas TJ, Ozorowski G, Nogal B, Perez L, LaBranche CC, Lim J, Francomano E, Wilson IA, Sanders RW, Ward AB, Montefiori DC, Nussenzweig MC, et al. Neutralizing antibody induction by HIV-1 Envelope glycoprotein SOSIP trimers on iron oxide nanoparticles may be impaired by mannose binding lectin. Journal of Virology. PMID 31852794 DOI: 10.1128/Jvi.01883-19 |
0.355 |
|
| 2019 |
Cohen YZ, Butler AL, Millard K, Witmer-Pack M, Levin R, Unson-O'Brien C, Patel R, Shimeliovich I, Lorenzi JCC, Horowitz J, Walsh SR, Lin S, Weiner JA, Tse A, Sato A, ... ... Nussenzweig MC, et al. Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study. Plos One. 14: e0219142. PMID 31393868 DOI: 10.1371/Journal.Pone.0219142 |
0.359 |
|
| 2019 |
Gaebler C, Lorenzi JCC, Oliveira TY, Nogueira L, Ramos V, Lu CL, Pai JA, Mendoza P, Jankovic M, Caskey M, Nussenzweig MC. Combination of quadruplex qPCR and next-generation sequencing for qualitative and quantitative analysis of the HIV-1 latent reservoir. The Journal of Experimental Medicine. PMID 31350309 DOI: 10.1084/Jem.20190896 |
0.349 |
|
| 2019 |
Finkin S, Hartweger H, Oliveira TY, Kara EE, Nussenzweig MC. Protein Amounts of the MYC Transcription Factor Determine Germinal Center B Cell Division Capacity. Immunity. PMID 31350178 DOI: 10.1016/J.Immuni.2019.06.013 |
0.398 |
|
| 2019 |
Dosenovic P, Pettersson AK, Wall A, Thientosapol ES, Feng J, Weidle C, Bhullar K, Kara EE, Hartweger H, Pai JA, Gray MD, Parks KR, Taylor JJ, Pancera M, Stamatatos L, ... Nussenzweig MC, et al. Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses. The Journal of Experimental Medicine. PMID 31345931 DOI: 10.1084/Jem.20190446 |
0.484 |
|
| 2019 |
Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West AP, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, ... ... Nussenzweig MC, et al. Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature. PMID 31142836 DOI: 10.1038/S41586-019-1250-Z |
0.457 |
|
| 2019 |
Schoofs T, Barnes CO, Suh-Toma N, Golijanin J, Schommers P, Gruell H, West AP, Bach F, Lee YE, Nogueira L, Georgiev IS, Bailer RT, Czartoski J, Mascola JR, Seaman MS, ... ... Nussenzweig MC, et al. Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity. PMID 31126879 DOI: 10.1016/J.Immuni.2019.04.014 |
0.386 |
|
| 2019 |
Hartweger H, McGuire AT, Horning M, Taylor JJ, Dosenovic P, Yost D, Gazumyan A, Seaman MS, Stamatatos L, Jankovic M, Nussenzweig MC. HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells. The Journal of Experimental Medicine. PMID 30975893 DOI: 10.1084/Jem.20190287 |
0.45 |
|
| 2019 |
Caskey M, Klein F, Nussenzweig MC. Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic. Nature Medicine. 25: 547-553. PMID 30936546 DOI: 10.1038/S41591-019-0412-8 |
0.381 |
|
| 2019 |
Vibholm LK, Lorenzi JCC, Pai JA, Cohen YZ, Oliveira TY, Barton JP, Noceda MG, Lu CL, Ablanedo-Terrazas Y, Del Rio Estrada PM, Reyes Teran G, Tolstrup M, Denton PW, Damsgaard T, Søgaard OS, ... Nussenzweig MC, et al. Characterization of intact proviruses in blood and lymph node from HIV-infected individuals undergoing analytical treatment interruption. Journal of Virology. PMID 30700598 DOI: 10.1128/Jvi.01920-18 |
0.338 |
|
| 2019 |
Hartweger H, Jankovic M, Nussenzweig MC. Abstract B113: Protective serum responses by CRISPR/Cas9-edited primary B cells expressing antibodies of choice Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B113 |
0.491 |
|
| 2018 |
Lu CL, Pai JA, Nogueira L, Mendoza P, Gruell H, Oliveira TY, Barton J, Lorenzi JCC, Cohen YZ, Cohn LB, Klein F, Caskey M, Nussenzweig MC, Jankovic M. Relationship between intact HIV-1 proviruses in circulating CD4 T cells and rebound viruses emerging during treatment interruption. Proceedings of the National Academy of Sciences of the United States of America. PMID 30420517 DOI: 10.1073/Pnas.1813512115 |
0.363 |
|
| 2018 |
Keeffe JR, Van Rompay KKA, Olsen PC, Wang Q, Gazumyan A, Azzopardi SA, Schaefer-Babajew D, Lee YE, Stuart JB, Singapuri A, Watanabe J, Usachenko J, Ardeshir A, Saeed M, Agudelo M, ... ... Nussenzweig MC, et al. A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell Reports. 25: 1385-1394.e7. PMID 30403995 DOI: 10.1016/J.Celrep.2018.10.031 |
0.36 |
|
| 2018 |
Delgado-Benito V, Rosen DB, Wang Q, Gazumyan A, Pai JA, Oliveira TY, Sundaravinayagam D, Zhang W, Andreani M, Keller L, Kieffer-Kwon KR, Pękowska A, Jung S, Driesner M, Subbotin RI, ... ... Nussenzweig MC, et al. The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination. Molecular Cell. PMID 30293785 DOI: 10.1016/J.Molcel.2018.08.042 |
0.366 |
|
| 2018 |
Bar-On Y, Gruell H, Schoofs T, Pai JA, Nogueira L, Butler AL, Millard K, Lehmann C, Suárez I, Oliveira TY, Karagounis T, Cohen YZ, Wyen C, Scholten S, Handl L, ... ... Nussenzweig MC, et al. Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals. Nature Medicine. PMID 30258217 DOI: 10.1038/S41591-018-0186-4 |
0.385 |
|
| 2018 |
Mendoza P, Gruell H, Nogueira L, Pai JA, Butler AL, Millard K, Lehmann C, Suárez I, Oliveira TY, Lorenzi JCC, Cohen YZ, Wyen C, Kümmerle T, Karagounis T, Lu CL, ... ... Nussenzweig MC, et al. Combination therapy with anti-HIV-1 antibodies maintains viral suppression. Nature. 561: 479-484. PMID 30258136 DOI: 10.1038/S41586-018-0531-2 |
0.396 |
|
| 2018 |
Kong XF, Martinez-Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick EK, Ma CS, Breton G, Lucero KB, Langlais D, Bousfiha A, Aytekin C, Markle J, Trouillet C, Jabot-Hanin F, ... ... Nussenzweig MC, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nature Immunology. PMID 30127434 DOI: 10.1038/S41590-018-0178-Z |
0.373 |
|
| 2018 |
Cohen YZ, Lorenzi JCC, Krassnig L, Barton JP, Burke L, Pai J, Lu CL, Mendoza P, Oliveira TY, Sleckman C, Millard K, Butler AL, Dizon JP, Belblidia SA, Witmer-Pack M, ... ... Nussenzweig MC, et al. Relationship between latent and rebound viruses in a clinical trial of anti-HIV-1 antibody 3BNC117. The Journal of Experimental Medicine. PMID 30072495 DOI: 10.1084/Jem.20180936 |
0.343 |
|
| 2018 |
Cohn LB, da Silva IT, Valieris R, Huang AS, Lorenzi JCC, Cohen YZ, Pai JA, Butler AL, Caskey M, Jankovic M, Nussenzweig MC. Clonal CD4 T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation. Nature Medicine. PMID 29686423 DOI: 10.1038/S41591-018-0017-7 |
0.414 |
|
| 2018 |
Dosenovic P, Kara EE, Pettersson AK, McGuire AT, Gray M, Hartweger H, Thientosapol ES, Stamatatos L, Nussenzweig MC. Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29666227 DOI: 10.1073/Pnas.1803457115 |
0.49 |
|
| 2018 |
Gautam R, Nishimura Y, Gaughan N, Gazumyan A, Schoofs T, Buckler-White A, Seaman MS, Swihart BJ, Follmann DA, Nussenzweig MC, Martin MA. A single injection of crystallizable fragment domain-modified antibodies elicits durable protection from SHIV infection. Nature Medicine. PMID 29662199 DOI: 10.1038/S41591-018-0001-2 |
0.402 |
|
| 2018 |
Kara EE, Nussenzweig MC. Redemption for self-reactive antibodies. Science (New York, N.Y.). 360: 152-153. PMID 29650658 DOI: 10.1126/Science.Aat5758 |
0.416 |
|
| 2018 |
Barnes CO, Gristick HB, Freund NT, Escolano A, Lyubimov AY, Hartweger H, West AP, Cohen AE, Nussenzweig MC, Bjorkman PJ. Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope. Nature Communications. 9: 1251. PMID 29593217 DOI: 10.1038/S41467-018-03632-Y |
0.383 |
|
| 2018 |
Wagh K, Seaman MS, Zingg M, Fitzsimons T, Barouch DH, Burton DR, Connors M, Ho DD, Mascola JR, Nussenzweig MC, Ravetch J, Gautam R, Martin MA, Montefiori DC, Korber B. Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections. Plos Pathogens. 14: e1006860. PMID 29505593 DOI: 10.1371/Journal.Ppat.1006860 |
0.358 |
|
| 2018 |
Wang H, Barnes CO, Yang Z, Nussenzweig MC, Bjorkman PJ. Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion. Cell Host & Microbe. 24: 579. DOI: 10.2210/Pdb6Edu/Pdb |
0.321 |
|
| 2017 |
Cohen YZ, Lorenzi JCC, Seaman MS, Nogueira L, Schoofs T, Krassnig L, Butler A, Millard K, Fitzsimons T, Daniell X, Dizon JP, Shimeliovich I, Montefiori DC, Caskey M, Nussenzweig MC. Neutralizing activity of broadly neutralizing anti-HIV-1 antibodies against clade B clinical isolates produced in peripheral blood mononuclear cells. Journal of Virology. PMID 29237833 DOI: 10.1128/Jvi.01883-17 |
0.433 |
|
| 2017 |
Mayer CT, Gazumyan A, Kara EE, Gitlin AD, Golijanin J, Viant C, Pai J, Oliveira TY, Wang Q, Escolano A, Medina-Ramirez M, Sanders RW, Nussenzweig MC. The microanatomic segregation of selection by apoptosis in the germinal center. Science (New York, N.Y.). PMID 28935768 DOI: 10.1126/Science.Aao2602 |
0.373 |
|
| 2017 |
Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye SW, Del Moral-Sanchez I, McGuire AT, Yasmeen A, Behrens AJ, Ozorowski G, van den Kerkhof TLGM, Freund NT, Dosenovic P, Hua Y, Gitlin AD, ... ... Nussenzweig MC, et al. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. The Journal of Experimental Medicine. PMID 28847869 DOI: 10.1084/Jem.20161160 |
0.446 |
|
| 2017 |
Horwitz JA, Bar-On Y, Lu CL, Fera D, Lockhart AAK, Lorenzi JCC, Nogueira L, Golijanin J, Scheid JF, Seaman MS, Gazumyan A, Zolla-Pazner S, Nussenzweig MC. Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo. Cell. PMID 28757252 DOI: 10.1016/J.Cell.2017.06.048 |
0.398 |
|
| 2017 |
Wang H, Gristick HB, Scharf L, West AP, Galimidi RP, Seaman MS, Freund NT, Nussenzweig MC, Bjorkman PJ. Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies. Elife. 6. PMID 28548638 DOI: 10.7554/Elife.27389 |
0.367 |
|
| 2017 |
Robbiani DF, Bozzacco L, Keeffe JR, Khouri R, Olsen PC, Gazumyan A, Schaefer-Babajew D, Avila-Rios S, Nogueira L, Patel R, Azzopardi SA, Uhl LFK, Saeed M, Sevilla-Reyes EE, Agudelo M, ... ... Nussenzweig MC, et al. Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell. 169: 597-609.e11. PMID 28475892 DOI: 10.1016/J.Cell.2017.04.024 |
0.38 |
|
| 2017 |
Cohn LB, Nussenzweig MC. HIV: Persistence through division. The Journal of Experimental Medicine. PMID 28348204 DOI: 10.1084/Jem.20170463 |
0.338 |
|
| 2017 |
Nishimura Y, Gautam R, Chun TW, Sadjadpour R, Foulds KE, Shingai M, Klein F, Gazumyan A, Golijanin J, Donaldson M, Donau OK, Plishka RJ, Buckler-White A, Seaman MS, Lifson JD, ... ... Nussenzweig MC, et al. Early antibody therapy can induce long-lasting immunity to SHIV. Nature. PMID 28289286 DOI: 10.1038/Nature21435 |
0.399 |
|
| 2017 |
Rommel PC, Oliveira TY, Nussenzweig MC, Robbiani DF. RAG1/2 induces genomic insertions by mobilizing DNA into RAG1/2-independent breaks. The Journal of Experimental Medicine. PMID 28179379 DOI: 10.1084/Jem.20161638 |
0.349 |
|
| 2017 |
Freund NT, Wang H, Scharf L, Nogueira L, Horwitz JA, Bar-On Y, Golijanin J, Sievers SA, Sok D, Cai H, Cesar Lorenzi JC, Halper-Stromberg A, Toth I, Piechocka-Trocha A, Gristick HB, ... ... Nussenzweig MC, et al. Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller. Science Translational Medicine. 9. PMID 28100831 DOI: 10.1126/Scitranslmed.Aal2144 |
0.396 |
|
| 2017 |
Caskey M, Schoofs T, Gruell H, Settler A, Karagounis T, Kreider EF, Murrell B, Pfeifer N, Nogueira L, Oliveira TY, Learn GH, Cohen YZ, Lehmann C, Gillor D, Shimeliovich I, ... ... Nussenzweig MC, et al. Antibody 10-1074 suppresses viremia in HIV-1-infected individuals. Nature Medicine. PMID 28092665 DOI: 10.1038/Nm.4268 |
0.404 |
|
| 2017 |
Wang H, Gristick HB, Scharf L, West AP, Galimidi RP, Seaman MS, Freund NT, Nussenzweig MC, Bjorkman PJ. Author response: Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies Elife. DOI: 10.7554/Elife.27389.032 |
0.37 |
|
| 2016 |
Escolano A, Dosenovic P, Nussenzweig MC. Progress toward active or passive HIV-1 vaccination. The Journal of Experimental Medicine. PMID 28003309 DOI: 10.1084/Jem.20161765 |
0.353 |
|
| 2016 |
Wang Q, Kieffer-Kwon KR, Oliveira TY, Mayer CT, Yao K, Pai J, Cao Z, Dose M, Casellas R, Jankovic M, Nussenzweig MC, Robbiani DF. The cell cycle restricts activation-induced cytidine deaminase activity to early G1. The Journal of Experimental Medicine. PMID 27998928 DOI: 10.1084/Jem.20161649 |
0.346 |
|
| 2016 |
Caskey M, Klein F, Nussenzweig MC. Broadly Neutralizing Antibodies for HIV-1 Prevention or Immunotherapy. The New England Journal of Medicine. 375: 2019-2021. PMID 27959740 DOI: 10.1056/Nejmp1613362 |
0.381 |
|
| 2016 |
Lorenzi JC, Cohen YZ, Cohn LB, Kreider EF, Barton JP, Learn GH, Oliveira T, Lavine CL, Horwitz JA, Settler A, Jankovic M, Seaman MS, Chakraborty AK, Hahn BH, Caskey M, ... Nussenzweig MC, et al. Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872306 DOI: 10.1073/Pnas.1617789113 |
0.348 |
|
| 2016 |
Breton G, Zheng S, Valieris R, Tojal da Silva I, Satija R, Nussenzweig MC. Human dendritic cells (DCs) are derived from distinct circulating precursors that are precommitted to become CD1c+ or CD141+ DCs. The Journal of Experimental Medicine. PMID 27864467 DOI: 10.1084/Jem.20161135 |
0.307 |
|
| 2016 |
von Boehmer L, Liu C, Ackerman S, Gitlin AD, Wang Q, Gazumyan A, Nussenzweig MC. Sequencing and cloning of antigen-specific antibodies from mouse memory B cells. Nature Protocols. 11: 1908-1923. PMID 27658009 DOI: 10.1038/Nprot.2016.102 |
0.424 |
|
| 2016 |
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, ... ... Nussenzweig MC, et al. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity. PMID 27617678 DOI: 10.1016/J.Immuni.2016.08.016 |
0.401 |
|
| 2016 |
Gristick HB, von Boehmer L, West AP, Schamber M, Gazumyan A, Golijanin J, Seaman MS, Fätkenheuer G, Klein F, Nussenzweig MC, Bjorkman PJ. Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nature Structural & Molecular Biology. PMID 27617431 DOI: 10.1038/Nsmb.3291 |
0.399 |
|
| 2016 |
Escolano A, Steichen JM, Dosenovic P, Kulp DW, Golijanin J, Sok D, Freund NT, Gitlin AD, Oliveira T, Araki T, Lowe S, Chen ST, Heinemann J, Yao KH, Georgeson E, ... ... Nussenzweig MC, et al. Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice. Cell. 166: 1445-1458.e12. PMID 27610569 DOI: 10.1016/J.Cell.2016.07.030 |
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| 2016 |
Scheid JF, Horwitz JA, Bar-On Y, Kreider EF, Lu CL, Lorenzi JC, Feldmann A, Braunschweig M, Nogueira L, Oliveira T, Shimeliovich I, Patel R, Burke L, Cohen YZ, Hadrigan S, ... ... Nussenzweig MC, et al. HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption. Nature. PMID 27338952 DOI: 10.1038/Nature18929 |
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Bournazos S, Gazumyan A, Seaman MS, Nussenzweig MC, Ravetch JV. Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell. 165: 1609-20. PMID 27315478 DOI: 10.1016/J.Cell.2016.04.050 |
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Lu CL, Murakowski DK, Bournazos S, Schoofs T, Sarkar D, Halper-Stromberg A, Horwitz JA, Nogueira L, Golijanin J, Gazumyan A, Ravetch JV, Caskey M, Chakraborty AK, Nussenzweig MC. Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo. Science (New York, N.Y.). 352: 1001-4. PMID 27199430 DOI: 10.1126/Science.Aaf1279 |
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| 2016 |
Schoofs T, Klein F, Braunschweig M, Kreider EF, Feldmann A, Nogueira L, Oliveira T, Lorenzi JC, Parrish EH, Learn GH, West AP, Bjorkman PJ, Schlesinger SJ, Seaman MS, Czartoski J, ... ... Nussenzweig MC, et al. HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Science (New York, N.Y.). 352: 997-1001. PMID 27199429 DOI: 10.1126/Science.Aaf0972 |
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| 2016 |
Gautam R, Nishimura Y, Pegu A, Nason MC, Klein F, Gazumyan A, Golijanin J, Buckler-White A, Sadjadpour R, Wang K, Mankoff Z, Schmidt SD, Lifson JD, Mascola JR, Nussenzweig MC, et al. A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges. Nature. PMID 27120156 DOI: 10.1038/Nature17677 |
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| 2016 |
Loschko J, Rieke GJ, Schreiber HA, Meredith MM, Yao KH, Guermonprez P, Nussenzweig MC. Inducible targeting of cDCs and their subsets in vivo. Journal of Immunological Methods. PMID 27073171 DOI: 10.1016/J.Jim.2016.04.004 |
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| 2016 |
Wagh K, Bhattacharya T, Williamson C, Robles A, Bayne M, Garrity J, Rist M, Rademeyer C, Yoon H, Lapedes A, Gao H, Greene K, Louder MK, Kong R, Karim SA, ... ... Nussenzweig MC, et al. Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection. Plos Pathogens. 12: e1005520. PMID 27028935 DOI: 10.1371/Journal.Ppat.1005520 |
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| 2016 |
Caskey M, Klein F, Lorenzi JC, Seaman MS, West AP, Buckley N, Kremer G, Nogueira L, Braunschweig M, Scheid JF, Horwitz JA, Shimeliovich I, Ben-Avraham S, Witmer-Pack M, Platten M, ... ... Nussenzweig MC, et al. Corrigendum: Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117. Nature. PMID 27007847 DOI: 10.1038/Nature17642 |
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| 2016 |
Loschko J, Schreiber HA, Rieke GJ, Esterházy D, Meredith MM, Pedicord VA, Yao KH, Caballero S, Pamer EG, Mucida D, Nussenzweig MC. Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation. The Journal of Experimental Medicine. PMID 27001748 DOI: 10.1084/Jem.20160062 |
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| 2016 |
Scharf L, West AP, Sievers SA, Chen C, Jiang S, Gao H, Gray MD, McGuire AT, Scheid JF, Nussenzweig MC, Stamatatos L, Bjorkman PJ. Structural basis for germline antibody recognition of HIV-1 immunogens. Elife. 5. PMID 26997349 DOI: 10.7554/Elife.13783 |
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| 2016 |
Gitlin AD, von Boehmer L, Gazumyan A, Shulman Z, Oliveira TY, Nussenzweig MC. Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory. Immunity. PMID 26944202 DOI: 10.1016/J.Immuni.2016.01.011 |
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| 2016 |
McGuire AT, Gray MD, Dosenovic P, Gitlin AD, Freund NT, Petersen J, Correnti C, Johnsen W, Kegel R, Stuart AB, Glenn J, Seaman MS, Schief WR, Strong RK, Nussenzweig MC, et al. Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice. Nature Communications. 7: 10618. PMID 26907590 DOI: 10.1038/Ncomms10618 |
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| 2016 |
Robbiani DF, Nussenzweig MC. A New Way to Diversify Antibodies by DNA Transposition. Cell. 164: 601-2. PMID 26871626 DOI: 10.1016/J.Cell.2016.01.031 |
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| 2016 |
Halper-Stromberg A, Nussenzweig MC. Towards HIV-1 remission: potential roles for broadly neutralizing antibodies. The Journal of Clinical Investigation. 126: 415-23. PMID 26752643 DOI: 10.1172/Jci80561 |
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| 2016 |
Scharf L, West AP, Sievers SA, Chen C, Jiang S, Gao H, Gray MD, McGuire AT, Scheid JF, Nussenzweig MC, Stamatatos L, Bjorkman PJ. Author response: Structural basis for germline antibody recognition of HIV-1 immunogens Elife. DOI: 10.7554/Elife.13783.028 |
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| 2016 |
Hartweger H, Finkin S, Nussenzweig MC. Abstract B144: Elucidating germinal center B cell metabolic states and their influence on selection Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B144 |
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| 2016 |
Nussenzweig M. D-108 Special lecture: Human antibodies to HIV-1 Journal of Acquired Immune Deficiency Syndromes. 71: 55. DOI: 10.1097/01.Qai.0000479556.36861.86 |
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| 2015 |
Freund NT, Horwitz JA, Nogueira L, Sievers SA, Scharf L, Scheid JF, Gazumyan A, Liu C, Velinzon K, Goldenthal A, Sanders RW, Moore JP, Bjorkman PJ, Seaman MS, Walker BD, ... ... Nussenzweig MC, et al. A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo. Plos Pathogens. 11: e1005238. PMID 26516768 DOI: 10.1371/Journal.Ppat.1005238 |
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| 2015 |
Zolla-Pazner S, Cohen SS, Boyd D, Kong XP, Seaman M, Nussenzweig M, Klein F, Overbaugh J, Totrov M. Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors that Affect Neutralization Sensitivity. Journal of Virology. PMID 26491157 DOI: 10.1128/Jvi.01645-15 |
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| 2015 |
Morgand M, Bouvin-Pley M, Plantier JC, Moreau A, Alessandri E, Simon F, Pace CS, Pancera M, Ho DD, Poignard P, Bjorkman PJ, Mouquet H, Nussenzweig MC, Kwong PD, Baty D, et al. A V1V2 neutralizing epitope is conserved in divergent non-M groups of HIV-1. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26413851 DOI: 10.1097/Qai.0000000000000854 |
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| 2015 |
Lee JH, Leaman DP, Kim AS, Torrents de la Peña A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, et al. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nature Communications. 6: 8167. PMID 26404402 DOI: 10.1038/Ncomms9167 |
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| 2015 |
Dong J, Panchakshari RA, Zhang T, Zhang Y, Hu J, Volpi SA, Meyers RM, Ho YJ, Du Z, Robbiani DF, Meng F, Gostissa M, Nussenzweig MC, Manis JP, Alt FW. Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching. Nature. 525: 134-9. PMID 26308889 DOI: 10.1038/Nature14970 |
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| 2015 |
Breton G, Lee J, Liu K, Nussenzweig MC. Defining human dendritic cell progenitors by multiparametric flow cytometry. Nature Protocols. 10: 1407-22. PMID 26292072 DOI: 10.1038/Nprot.2015.092 |
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| 2015 |
Robbiani DF, Deroubaix S, Feldhahn N, Oliveira TY, Callen E, Wang Q, Jankovic M, Silva IT, Rommel PC, Bosque D, Eisenreich T, Nussenzweig A, Nussenzweig MC. Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma. Cell. 162: 727-37. PMID 26276629 DOI: 10.1016/J.Cell.2015.07.019 |
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| 2015 |
Gitlin AD, Mayer CT, Oliveira TY, Shulman Z, Jones MJ, Koren A, Nussenzweig MC. T cell help controls the speed of the cell cycle in germinal center B cells. Science (New York, N.Y.). PMID 26184917 DOI: 10.1126/Science.Aac4919 |
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| 2015 |
Dosenovic P, von Boehmer L, Escolano A, Jardine J, Freund NT, Gitlin AD, McGuire AT, Kulp DW, Oliveira T, Scharf L, Pietzsch J, Gray MD, Cupo A, van Gils MJ, Yao KH, ... ... Nussenzweig MC, et al. Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice. Cell. 161: 1505-15. PMID 26091035 DOI: 10.1016/J.Cell.2015.06.003 |
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| 2015 |
Lee J, Breton G, Aljoufi A, Zhou YJ, Puhr S, Nussenzweig MC, Liu K. Clonal analysis of human dendritic cell progenitor using a stromal cell culture. Journal of Immunological Methods. PMID 26056939 DOI: 10.1016/J.Jim.2015.06.004 |
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| 2015 |
Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, ... ... Nussenzweig MC, et al. Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell. 161: 1280-92. PMID 26004070 DOI: 10.1016/J.Cell.2015.05.007 |
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| 2015 |
Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Martin L, ... ... Nussenzweig MC, et al. Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas. Mbio. 6. PMID 25900654 DOI: 10.1128/Mbio.00296-15 |
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| 2015 |
Caskey M, Klein F, Lorenzi JC, Seaman MS, West AP, Buckley N, Kremer G, Nogueira L, Braunschweig M, Scheid JF, Horwitz JA, Shimeliovich I, Ben-Avraham S, Witmer-Pack M, Platten M, ... ... Nussenzweig MC, et al. Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117. Nature. 522: 487-91. PMID 25855300 DOI: 10.1038/Nature14411 |
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Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, ... ... Nussenzweig MC, et al. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 519: 87-91. PMID 25707797 DOI: 10.1038/Nature14264 |
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| 2015 |
Lee J, Breton G, Oliveira TY, Zhou YJ, Aljoufi A, Puhr S, Cameron MJ, Sékaly RP, Nussenzweig MC, Liu K. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. The Journal of Experimental Medicine. 212: 385-99. PMID 25687283 DOI: 10.1084/Jem.20141442 |
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| 2015 |
Breton G, Lee J, Zhou YJ, Schreiber JJ, Keler T, Puhr S, Anandasabapathy N, Schlesinger S, Caskey M, Liu K, Nussenzweig MC. Circulating precursors of human CD1c+ and CD141+ dendritic cells. The Journal of Experimental Medicine. 212: 401-13. PMID 25687281 DOI: 10.1084/Jem.20141441 |
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| 2015 |
Freund NT, Scheid JF, Mouquet H, Nussenzweig MC. Amplification of highly mutated human Ig lambda light chains from an HIV-1 infected patient. Journal of Immunological Methods. 418: 61-5. PMID 25667013 DOI: 10.1016/J.Jim.2015.01.011 |
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| 2015 |
Galimidi RP, Klein JS, Politzer MS, Bai S, Seaman MS, Nussenzweig MC, West AP, Bjorkman PJ. Intra-spike crosslinking overcomes antibody evasion by HIV-1. Cell. 160: 433-46. PMID 25635457 DOI: 10.1016/J.Cell.2015.01.016 |
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| 2015 |
Cohn LB, Silva IT, Oliveira TY, Rosales RA, Parrish EH, Learn GH, Hahn BH, Czartoski JL, McElrath MJ, Lehmann C, Klein F, Caskey M, Walker BD, Siliciano JD, Siliciano RF, ... ... Nussenzweig MC, et al. HIV-1 integration landscape during latent and active infection. Cell. 160: 420-32. PMID 25635456 DOI: 10.1016/J.Cell.2015.01.020 |
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| 2015 |
Gitlin AD, Nussenzweig MC. Immunology: Fifty years of B lymphocytes. Nature. 517: 139-41. PMID 25567266 DOI: 10.1038/517139A |
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| 2015 |
Kong R, Louder MK, Wagh K, Bailer RT, deCamp A, Greene K, Gao H, Taft JD, Gazumyan A, Liu C, Nussenzweig MC, Korber B, Montefiori DC, Mascola JR. Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes. Journal of Virology. 89: 2659-71. PMID 25520506 DOI: 10.1128/Jvi.03136-14 |
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Kracker S, Di Virgilio M, Schwartzentruber J, Cuenin C, Forveille M, Deau MC, McBride KM, Majewski J, Gazumyan A, Seneviratne S, Grimbacher B, Kutukculer N, Herceg Z, Cavazzana M, Jabado N, ... Nussenzweig MC, et al. An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex. The Journal of Allergy and Clinical Immunology. 135: 998-1007.e6. PMID 25312759 DOI: 10.1016/J.Jaci.2014.08.030 |
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| 2014 |
Wang Q, Oliveira T, Jankovic M, Silva IT, Hakim O, Yao K, Gazumyan A, Mayer CT, Pavri R, Casellas R, Nussenzweig MC, Robbiani DF. Epigenetic targeting of activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America. 111: 18667-72. PMID 25512519 DOI: 10.1073/Pnas.1420575111 |
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| 2014 |
Qian J, Wang Q, Dose M, Pruett N, Kieffer-Kwon KR, Resch W, Liang G, Tang Z, Mathé E, Benner C, Dubois W, Nelson S, Vian L, Oliveira TY, Jankovic M, ... ... Nussenzweig MC, et al. B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity. Cell. 159: 1524-37. PMID 25483777 DOI: 10.1016/J.Cell.2014.11.013 |
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| 2014 |
Meng FL, Du Z, Federation A, Hu J, Wang Q, Kieffer-Kwon KR, Meyers RM, Amor C, Wasserman CR, Neuberg D, Casellas R, Nussenzweig MC, Bradner JE, Liu XS, Alt FW. Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability. Cell. 159: 1538-48. PMID 25483776 DOI: 10.1016/J.Cell.2014.11.014 |
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| 2014 |
Klein F, Nogueira L, Nishimura Y, Phad G, West AP, Halper-Stromberg A, Horwitz JA, Gazumyan A, Liu C, Eisenreich TR, Lehmann C, Fätkenheuer G, Williams C, Shingai M, Martin MA, ... ... Nussenzweig MC, et al. Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants. The Journal of Experimental Medicine. 211: 2361-72. PMID 25385756 DOI: 10.1084/Jem.20141050 |
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| 2014 |
Fridy PC, Li Y, Keegan S, Thompson MK, Nudelman I, Scheid JF, Oeffinger M, Nussenzweig MC, Fenyö D, Chait BT, Rout MP. A robust pipeline for rapid production of versatile nanobody repertoires. Nature Methods. 11: 1253-60. PMID 25362362 DOI: 10.1038/Nmeth.3170 |
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| 2014 |
Bouvin-Pley M, Morgand M, Meyer L, Goujard C, Moreau A, Mouquet H, Nussenzweig M, Pace C, Ho D, Bjorkman PJ, Baty D, Chames P, Pancera M, Kwong PD, Poignard P, et al. Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies. Journal of Virology. 88: 13910-7. PMID 25231299 DOI: 10.1128/Jvi.02083-14 |
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| 2014 |
Bournazos S, Klein F, Pietzsch J, Seaman MS, Nussenzweig MC, Ravetch JV. Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity. Cell. 158: 1243-53. PMID 25215485 DOI: 10.1016/J.Cell.2014.08.023 |
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| 2014 |
Shulman Z, Gitlin AD, Weinstein JS, Lainez B, Esplugues E, Flavell RA, Craft JE, Nussenzweig MC. Dynamic signaling by T follicular helper cells during germinal center B cell selection. Science (New York, N.Y.). 345: 1058-62. PMID 25170154 DOI: 10.1126/Science.1257861 |
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| 2014 |
Shingai M, Donau OK, Plishka RJ, Buckler-White A, Mascola JR, Nabel GJ, Nason MC, Montefiori D, Moldt B, Poignard P, Diskin R, Bjorkman PJ, Eckhaus MA, Klein F, Mouquet H, ... ... Nussenzweig MC, et al. Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques. The Journal of Experimental Medicine. 211: 2061-74. PMID 25155019 DOI: 10.1084/Jem.20132494 |
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| 2014 |
Anandasabapathy N, Feder R, Mollah S, Tse SW, Longhi MP, Mehandru S, Matos I, Cheong C, Ruane D, Brane L, Teixeira A, Dobrin J, Mizenina O, Park CG, Meredith M, ... ... Nussenzweig MC, et al. Classical Flt3L-dependent dendritic cells control immunity to protein vaccine. The Journal of Experimental Medicine. 211: 1875-91. PMID 25135299 DOI: 10.1084/Jem.20131397 |
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| 2014 |
Halper-Stromberg A, Lu CL, Klein F, Horwitz JA, Bournazos S, Nogueira L, Eisenreich TR, Liu C, Gazumyan A, Schaefer U, Furze RC, Seaman MS, Prinjha R, Tarakhovsky A, Ravetch JV, ... Nussenzweig MC, et al. Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice. Cell. 158: 989-99. PMID 25131989 DOI: 10.1016/J.Cell.2014.07.043 |
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| 2014 |
Neubert K, Lehmann CH, Heger L, Baranska A, Staedtler AM, Buchholz VR, Yamazaki S, Heidkamp GF, Eissing N, Zebroski H, Nussenzweig MC, Nimmerjahn F, Dudziak D. Antigen delivery to CD11c+CD8- dendritic cells induces protective immune responses against experimental melanoma in mice in vivo. Journal of Immunology (Baltimore, Md. : 1950). 192: 5830-8. PMID 24829411 DOI: 10.4049/Jimmunol.1300975 |
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| 2014 |
Gitlin AD, Shulman Z, Nussenzweig MC. Clonal selection in the germinal centre by regulated proliferation and hypermutation. Nature. 509: 637-40. PMID 24805232 DOI: 10.1038/Nature13300 |
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| 2014 |
Scharf L, Scheid JF, Lee JH, West AP, Chen C, Gao H, Gnanapragasam PN, Mares R, Seaman MS, Ward AB, Nussenzweig MC, Bjorkman PJ. Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell Reports. 7: 785-95. PMID 24767986 DOI: 10.1016/J.Celrep.2014.04.001 |
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| 2014 |
West AP, Scharf L, Scheid JF, Klein F, Bjorkman PJ, Nussenzweig MC. Structural insights on the role of antibodies in HIV-1 vaccine and therapy. Cell. 156: 633-48. PMID 24529371 DOI: 10.1016/J.Cell.2014.01.052 |
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| 2014 |
KC W, Satpathy AT, Rapaport AS, Briseño CG, Wu X, Albring JC, Russler-Germain EV, Kretzer NM, Durai V, Persaud SP, Edelson BT, Loschko J, Cella M, Allen PM, Nussenzweig MC, et al. L-Myc expression by dendritic cells is required for optimal T-cell priming. Nature. 507: 243-7. PMID 24509714 DOI: 10.1038/Nature12967 |
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| 2014 |
Fooksman DR, Nussenzweig MC, Dustin ML. Myeloid cells limit production of antibody-secreting cells after immunization in the lymph node. Journal of Immunology (Baltimore, Md. : 1950). 192: 1004-12. PMID 24376270 DOI: 10.4049/Jimmunol.1300977 |
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| 2014 |
Diskin R, Scheid J, West A, Klein F, Nussenzweig M, Bjorkman P. Targeting HIV using Structure-Based Rational Design of Antibodies Acta Crystallographica Section a Foundations and Advances. 70: C119-C119. DOI: 10.1107/S2053273314098805 |
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| 2014 |
Sievers SA, Patel SN, Bennett K, Klein F, Nussenzweig MC, Bjorkman PJ. Engineering Antibodies to Enhance Activity and Increase Half-life Aids Research and Human Retroviruses. 30: A210-A210. DOI: 10.1089/Aid.2014.5456.Abstract |
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| 2014 |
Courtney C, Mayr L, Nogueira L, Ngai J, Seaman M, Klein F, Nussenzweig M, Nyambi P, Zolla-Pazner S. Investigating Broad Neutralization in HIV-1 Non-B Subtype Infection in Yaoundé, Cameroon. Aids Research and Human Retroviruses. 30. DOI: 10.1089/Aid.2014.5311.Abstract |
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| 2014 |
KC W, Satpathy AT, Rapaport AS, Briseño CG, Wu X, Albring JC, Russler-Germain EV, Kretzer NM, Durai V, Persaud SP, Edelson BT, Loschko J, Cella M, Allen PM, Nussenzweig MC, et al. MONDAY PUSHLIVE TEST L-Myc expression by dendritic cells is required for optimal T-cell priming Nature. DOI: 10.1038/Monday_Push_Test_Nature12967 |
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| 2013 |
Malbec M, Porrot F, Rua R, Horwitz J, Klein F, Halper-Stromberg A, Scheid JF, Eden C, Mouquet H, Nussenzweig MC, Schwartz O. Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission. The Journal of Experimental Medicine. 210: 2813-21. PMID 24277152 DOI: 10.1084/Jem.20131244 |
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| 2013 |
Barouch DH, Whitney JB, Moldt B, Klein F, Oliveira TY, Liu J, Stephenson KE, Chang HW, Shekhar K, Gupta S, Nkolola JP, Seaman MS, Smith KM, Borducchi EN, Cabral C, ... ... Nussenzweig MC, et al. Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys. Nature. 503: 224-8. PMID 24172905 DOI: 10.1038/Nature12744 |
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| 2013 |
Shingai M, Nishimura Y, Klein F, Mouquet H, Donau OK, Plishka R, Buckler-White A, Seaman M, Piatak M, Lifson JD, Dimitrov DS, Nussenzweig MC, Martin MA. Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia. Nature. 503: 277-80. PMID 24172896 DOI: 10.1038/Nature12746 |
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| 2013 |
Horwitz JA, Halper-Stromberg A, Mouquet H, Gitlin AD, Tretiakova A, Eisenreich TR, Malbec M, Gravemann S, Billerbeck E, Dorner M, Büning H, Schwartz O, Knops E, Kaiser R, Seaman MS, ... ... Nussenzweig MC, et al. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 16538-43. PMID 24043801 DOI: 10.1073/Pnas.1315295110 |
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| 2013 |
Schreiber HA, Loschko J, Karssemeijer RA, Escolano A, Meredith MM, Mucida D, Guermonprez P, Nussenzweig MC. Intestinal monocytes and macrophages are required for T cell polarization in response to Citrobacter rodentium. The Journal of Experimental Medicine. 210: 2025-39. PMID 24043764 DOI: 10.1084/Jem.20130903 |
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| 2013 |
Gaebler C, Gruell H, Velinzon K, Scheid JF, Nussenzweig MC, Klein F. Isolation of HIV-1-reactive antibodies using cell surface-expressed gp160Δc(BaL.). Journal of Immunological Methods. 397: 47-54. PMID 24041474 DOI: 10.1016/J.Jim.2013.09.003 |
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| 2013 |
Klein F, Mouquet H, Dosenovic P, Scheid JF, Scharf L, Nussenzweig MC. Antibodies in HIV-1 vaccine development and therapy. Science (New York, N.Y.). 341: 1199-204. PMID 24031012 DOI: 10.1126/Science.1241144 |
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| 2013 |
Satpathy AT, Briseño CG, Lee JS, Ng D, Manieri NA, Kc W, Wu X, Thomas SR, Lee WL, Turkoz M, McDonald KG, Meredith MM, Song C, Guidos CJ, Newberry RD, ... ... Nussenzweig MC, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nature Immunology. 14: 937-48. PMID 23913046 DOI: 10.1038/Ni.2679 |
0.3 |
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| 2013 |
Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, Georgiev IS, Altae-Tran HR, Chuang GY, Joyce MG, Do Kwon Y, Longo NS, Louder MK, Luongo T, McKee K, ... ... Nussenzweig MC, et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity. 39: 245-58. PMID 23911655 DOI: 10.1016/J.Immuni.2013.04.012 |
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| 2013 |
Shulman Z, Gitlin AD, Targ S, Jankovic M, Pasqual G, Nussenzweig MC, Victora GD. T follicular helper cell dynamics in germinal centers. Science (New York, N.Y.). 341: 673-7. PMID 23887872 DOI: 10.1126/Science.1241680 |
0.355 |
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| 2013 |
Rommel PC, Bosque D, Gitlin AD, Croft GF, Heintz N, Casellas R, Nussenzweig MC, Kriaucionis S, Robbiani DF. Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development. Plos One. 8: e69208. PMID 23861962 DOI: 10.1371/Journal.Pone.0069208 |
0.402 |
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| 2013 |
Chuang GY, Acharya P, Schmidt SD, Yang Y, Louder MK, Zhou T, Kwon YD, Pancera M, Bailer RT, Doria-Rose NA, Nussenzweig MC, Mascola JR, Kwong PD, Georgiev IS. Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains. Journal of Virology. 87: 10047-58. PMID 23843642 DOI: 10.1128/Jvi.00984-13 |
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| 2013 |
West AP, Scharf L, Horwitz J, Klein F, Nussenzweig MC, Bjorkman PJ. Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues. Proceedings of the National Academy of Sciences of the United States of America. 110: 10598-603. PMID 23754383 DOI: 10.1073/Pnas.1309215110 |
0.4 |
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| 2013 |
Callen E, Di Virgilio M, Kruhlak MJ, Nieto-Soler M, Wong N, Chen HT, Faryabi RB, Polato F, Santos M, Starnes LM, Wesemann DR, Lee JE, Tubbs A, Sleckman BP, Daniel JA, ... ... Nussenzweig MC, et al. 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions. Cell. 153: 1266-80. PMID 23727112 DOI: 10.1016/J.Cell.2013.05.023 |
0.302 |
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| 2013 |
Gruell H, Bournazos S, Ravetch JV, Ploss A, Nussenzweig MC, Pietzsch J. Antibody and antiretroviral preexposure prophylaxis prevent cervicovaginal HIV-1 infection in a transgenic mouse model. Journal of Virology. 87: 8535-44. PMID 23720722 DOI: 10.1128/Jvi.00868-13 |
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| 2013 |
Diskin R, Klein F, Horwitz JA, Halper-Stromberg A, Sather DN, Marcovecchio PM, Lee T, West AP, Gao H, Seaman MS, Stamatatos L, Nussenzweig MC, Bjorkman PJ. Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies. The Journal of Experimental Medicine. 210: 1235-49. PMID 23712429 DOI: 10.1084/Jem.20130221 |
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| 2013 |
Guermonprez P, Helft J, Claser C, Deroubaix S, Karanje H, Gazumyan A, Darasse-Jèze G, Telerman SB, Breton G, Schreiber HA, Frias-Staheli N, Billerbeck E, Dorner M, Rice CM, Ploss A, ... ... Nussenzweig MC, et al. Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection. Nature Medicine. 19: 730-8. PMID 23685841 DOI: 10.1038/Nm.3197 |
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| 2013 |
Mouquet H, Nussenzweig MC. HIV: Roadmaps to a vaccine. Nature. 496: 441-2. PMID 23552894 DOI: 10.1038/Nature12091 |
0.388 |
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| 2013 |
Klein F, Diskin R, Scheid JF, Gaebler C, Mouquet H, Georgiev IS, Pancera M, Zhou T, Incesu RB, Fu BZ, Gnanapragasam PN, Oliveira TY, Seaman MS, Kwong PD, Bjorkman PJ, ... Nussenzweig MC, et al. Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell. 153: 126-38. PMID 23540694 DOI: 10.1016/J.Cell.2013.03.018 |
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| 2013 |
Scharf L, West AP, Gao H, Lee T, Scheid JF, Nussenzweig MC, Bjorkman PJ, Diskin R. Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America. 110: 6049-54. PMID 23524883 DOI: 10.1073/Pnas.1303682110 |
0.397 |
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| 2013 |
Lottersberger F, Bothmer A, Robbiani DF, Nussenzweig MC, de Lange T. Role of 53BP1 oligomerization in regulating double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America. 110: 2146-51. PMID 23345425 DOI: 10.1073/Pnas.1222617110 |
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| 2013 |
Di Virgilio M, Callen E, Yamane A, Zhang W, Jankovic M, Gitlin AD, Feldhahn N, Resch W, Oliveira TY, Chait BT, Nussenzweig A, Casellas R, Robbiani DF, Nussenzweig MC. Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science (New York, N.Y.). 339: 711-5. PMID 23306439 DOI: 10.1126/Science.1230624 |
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| 2013 |
Yamane A, Robbiani DF, Resch W, Bothmer A, Nakahashi H, Oliveira T, Rommel PC, Brown EJ, Nussenzweig A, Nussenzweig MC, Casellas R. RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle. Cell Reports. 3: 138-47. PMID 23291097 DOI: 10.1016/J.Celrep.2012.12.006 |
0.306 |
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| 2013 |
Jankovic M, Feldhahn N, Oliveira TY, Silva IT, Kieffer-Kwon KR, Yamane A, Resch W, Klein I, Robbiani DF, Casellas R, Nussenzweig MC. 53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma. Molecular Cell. 49: 623-31. PMID 23290917 DOI: 10.1016/J.Molcel.2012.11.029 |
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| 2013 |
Bothmer A, Rommel PC, Gazumyan A, Polato F, Reczek CR, Muellenbeck MF, Schaetzlein S, Edelmann W, Chen PL, Brosh RM, Casellas R, Ludwig T, Baer R, Nussenzweig A, Nussenzweig MC, et al. Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching. The Journal of Experimental Medicine. 210: 115-23. PMID 23254285 DOI: 10.1084/Jem.20121975 |
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| 2013 |
Robbiani DF, Nussenzweig MC. Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase. Annual Review of Pathology. 8: 79-103. PMID 22974238 DOI: 10.1146/Annurev-Pathol-020712-164004 |
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| 2013 |
Diskin R, Sather DN, Marcovecchio PM, Lee T, West AP, Gao H, Klein F, -Halper-Stromberg A, Horwitz J, Seaman MS, Stamatatos L, Nussenzweig MC, Bjorkman PJ. D106 Overcoming HIV pathways for escape using rationally-designed anti-HIV antibodies Jaids Journal of Acquired Immune Deficiency Syndromes. 62: S49. DOI: 10.1097/01.Qai.0000429234.07501.Af |
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| 2012 |
Mouquet H, Scharf L, Euler Z, Liu Y, Eden C, Scheid JF, Halper-Stromberg A, Gnanapragasam PN, Spencer DI, Seaman MS, Schuitemaker H, Feizi T, Nussenzweig MC, Bjorkman PJ. Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proceedings of the National Academy of Sciences of the United States of America. 109: E3268-77. PMID 23115339 DOI: 10.1073/Pnas.1217207109 |
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| 2012 |
Klein F, Halper-Stromberg A, Horwitz JA, Gruell H, Scheid JF, Bournazos S, Mouquet H, Spatz LA, Diskin R, Abadir A, Zang T, Dorner M, Billerbeck E, Labitt RN, Gaebler C, ... ... Nussenzweig MC, et al. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature. 492: 118-22. PMID 23103874 DOI: 10.1038/Nature11604 |
0.396 |
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| 2012 |
Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008 |
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| 2012 |
Pietzsch J, Gruell H, Bournazos S, Donovan BM, Klein F, Diskin R, Seaman MS, Bjorkman PJ, Ravetch JV, Ploss A, Nussenzweig MC. A mouse model for HIV-1 entry. Proceedings of the National Academy of Sciences of the United States of America. 109: 15859-64. PMID 23019371 DOI: 10.1073/Pnas.1213409109 |
0.377 |
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| 2012 |
Dominguez-Sola D, Victora GD, Ying CY, Phan RT, Saito M, Nussenzweig MC, Dalla-Favera R. The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry. Nature Immunology. 13: 1083-91. PMID 23001145 DOI: 10.1038/Ni.2428 |
0.37 |
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| 2012 |
Lahoud MH, Ahmet F, Zhang JG, Meuter S, Policheni AN, Kitsoulis S, Lee CN, O'Keeffe M, Sullivan LC, Brooks AG, Berry R, Rossjohn J, Mintern JD, Vega-Ramos J, Villadangos JA, ... ... Nussenzweig MC, et al. DEC-205 is a cell surface receptor for CpG oligonucleotides. Proceedings of the National Academy of Sciences of the United States of America. 109: 16270-5. PMID 22988114 DOI: 10.1073/Pnas.1208796109 |
0.378 |
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| 2012 |
Feldhahn N, Ferretti E, Robbiani DF, Callen E, Deroubaix S, Selleri L, Nussenzweig A, Nussenzweig MC. The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. The Embo Journal. 31: 4045-56. PMID 22940690 DOI: 10.1038/Emboj.2012.247 |
0.33 |
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| 2012 |
Meredith MM, Liu K, Kamphorst AO, Idoyaga J, Yamane A, Guermonprez P, Rihn S, Yao KH, Silva IT, Oliveira TY, Skokos D, Casellas R, Nussenzweig MC. Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state. The Journal of Experimental Medicine. 209: 1583-93. PMID 22851594 DOI: 10.1084/Jem.20121003 |
0.378 |
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| 2012 |
Klein F, Gaebler C, Mouquet H, Sather DN, Lehmann C, Scheid JF, Kraft Z, Liu Y, Pietzsch J, Hurley A, Poignard P, Feizi T, Morris L, Walker BD, Fätkenheuer G, ... ... Nussenzweig MC, et al. Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein. The Journal of Experimental Medicine. 209: 1469-79. PMID 22826297 DOI: 10.1084/Jem.20120423 |
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| 2012 |
West AP, Diskin R, Nussenzweig MC, Bjorkman PJ. Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120. Proceedings of the National Academy of Sciences of the United States of America. 109: E2083-90. PMID 22745174 DOI: 10.1073/Pnas.1208984109 |
0.394 |
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| 2012 |
Victora GD, Dominguez-Sola D, Holmes AB, Deroubaix S, Dalla-Favera R, Nussenzweig MC. Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas. Blood. 120: 2240-8. PMID 22740445 DOI: 10.1182/Blood-2012-03-415380 |
0.376 |
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| 2012 |
Kovalchuk AL, Ansarah-Sobrinho C, Hakim O, Resch W, Tolarová H, Dubois W, Yamane A, Takizawa M, Klein I, Hager GL, Morse HC, Potter M, Nussenzweig MC, Casellas R. Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation. Proceedings of the National Academy of Sciences of the United States of America. 109: 10972-7. PMID 22711821 DOI: 10.1073/Pnas.1200106109 |
0.313 |
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| 2012 |
Meredith MM, Liu K, Darrasse-Jeze G, Kamphorst AO, Schreiber HA, Guermonprez P, Idoyaga J, Cheong C, Yao KH, Niec RE, Nussenzweig MC. Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage. The Journal of Experimental Medicine. 209: 1153-65. PMID 22615130 DOI: 10.1084/Jem.20112675 |
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| 2012 |
Gazumyan A, Bothmer A, Klein IA, Nussenzweig MC, McBride KM. Activation-induced cytidine deaminase in antibody diversification and chromosome translocation. Advances in Cancer Research. 113: 167-90. PMID 22429855 DOI: 10.1016/B978-0-12-394280-7.00005-1 |
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| 2012 |
Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, ... ... Nussenzweig MC, et al. DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes. Nature. 484: 69-74. PMID 22314321 DOI: 10.1038/Nature10909 |
0.303 |
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| 2012 |
Boboila C, Oksenych V, Gostissa M, Wang JH, Zha S, Zhang Y, Chai H, Lee CS, Jankovic M, Saez LM, Nussenzweig MC, McKinnon PJ, Alt FW, Schwer B. Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1). Proceedings of the National Academy of Sciences of the United States of America. 109: 2473-8. PMID 22308491 DOI: 10.1073/Pnas.1121470109 |
0.37 |
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| 2012 |
Mouquet H, Warncke M, Scheid JF, Seaman MS, Nussenzweig MC. Enhanced HIV-1 neutralization by antibody heteroligation. Proceedings of the National Academy of Sciences of the United States of America. 109: 875-80. PMID 22219363 DOI: 10.1073/Pnas.1120059109 |
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| 2012 |
Mouquet H, Nussenzweig MC. Polyreactive antibodies in adaptive immune responses to viruses. Cellular and Molecular Life Sciences : Cmls. 69: 1435-45. PMID 22045557 DOI: 10.1007/S00018-011-0872-6 |
0.439 |
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| 2012 |
Oliveira TY, Resch W, Jankovic M, Casellas R, Nussenzweig MC, Klein IA. Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements. Journal of Immunological Methods. 375: 176-81. PMID 22033343 DOI: 10.1016/J.Jim.2011.10.007 |
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| 2011 |
Mellman I, Nussenzweig M. Retrospective. Ralph M. Steinman (1943-2011). Science (New York, N.Y.). 334: 466. PMID 22034425 DOI: 10.1126/Science.1215136 |
0.371 |
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| 2011 |
Diskin R, Scheid JF, Marcovecchio PM, West AP, Klein F, Gao H, Gnanapragasam PN, Abadir A, Seaman MS, Nussenzweig MC, Bjorkman PJ. Increasing the potency and breadth of an HIV antibody by using structure-based rational design. Science (New York, N.Y.). 334: 1289-93. PMID 22033520 DOI: 10.1126/Science.1213782 |
0.344 |
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| 2011 |
Scheid JF, Mouquet H, Kofer J, Yurasov S, Nussenzweig MC, Wardemann H. Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells Proceedings of the National Academy of Sciences of the United States of America. 108: 18044-18048. PMID 22025722 DOI: 10.1073/Pnas.1113395108 |
0.399 |
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| 2011 |
Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC. Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes. Cell. 147: 95-106. PMID 21962510 DOI: 10.1016/J.Cell.2011.07.048 |
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| 2011 |
Mouquet H, Klein F, Scheid JF, Warncke M, Pietzsch J, Oliveira TY, Velinzon K, Seaman MS, Nussenzweig MC. Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. Plos One. 6: e24078. PMID 21931643 DOI: 10.1371/Journal.Pone.0024078 |
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| 2011 |
Anandasabapathy N, Victora GD, Meredith M, Feder R, Dong B, Kluger C, Yao K, Dustin ML, Nussenzweig MC, Steinman RM, Liu K. Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain. The Journal of Experimental Medicine. 208: 1695-705. PMID 21788405 DOI: 10.1084/Jem.20102657 |
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| 2011 |
Scheid JF, Mouquet H, Ueberheide B, Diskin R, Klein F, Oliveira TY, Pietzsch J, Fenyo D, Abadir A, Velinzon K, Hurley A, Myung S, Boulad F, Poignard P, Burton DR, ... ... Nussenzweig MC, et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science (New York, N.Y.). 333: 1633-7. PMID 21764753 DOI: 10.1126/Science.1207227 |
0.41 |
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| 2011 |
Pavri R, Nussenzweig MC. AID targeting in antibody diversity. Advances in Immunology. 110: 1-26. PMID 21762814 DOI: 10.1016/B978-0-12-387663-8.00005-3 |
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| 2011 |
Schwickert TA, Victora GD, Fooksman DR, Kamphorst AO, Mugnier MR, Gitlin AD, Dustin ML, Nussenzweig MC. A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. The Journal of Experimental Medicine. 208: 1243-52. PMID 21576382 DOI: 10.1084/Jem.20102477 |
0.412 |
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| 2011 |
Gazumyan A, Timachova K, Yuen G, Siden E, Di Virgilio M, Woo EM, Chait BT, Reina San-Martin B, Nussenzweig MC, McBride KM. Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation. Molecular and Cellular Biology. 31: 442-9. PMID 21135131 DOI: 10.1128/Mcb.00349-10 |
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| 2011 |
Yamane A, Resch W, Kuo N, Kuchen S, Li Z, Sun HW, Robbiani DF, McBride K, Nussenzweig MC, Casellas R. Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes. Nature Immunology. 12: 62-9. PMID 21113164 DOI: 10.1038/Ni.1964 |
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| 2010 |
Victora GD, Schwickert TA, Fooksman DR, Kamphorst AO, Meyer-Hermann M, Dustin ML, Nussenzweig MC. Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell. 143: 592-605. PMID 21074050 DOI: 10.1016/J.Cell.2010.10.032 |
0.401 |
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| 2010 |
Pavri R, Gazumyan A, Jankovic M, Di Virgilio M, Klein I, Ansarah-Sobrinho C, Resch W, Yamane A, Reina San-Martin B, Barreto V, Nieland TJ, Root DE, Casellas R, Nussenzweig MC. Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell. 143: 122-33. PMID 20887897 DOI: 10.1016/J.Cell.2010.09.017 |
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| 2010 |
Mouquet H, Scheid JF, Zoller MJ, Krogsgaard M, Ott RG, Shukair S, Artyomov MN, Pietzsch J, Connors M, Pereyra F, Walker BD, Ho DD, Wilson PC, Seaman MS, Eisen HN, ... ... Nussenzweig MC, et al. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation. Nature. 467: 591-5. PMID 20882016 DOI: 10.1038/Nature09385 |
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| 2010 |
Liu K, Nussenzweig MC. Development and homeostasis of dendritic cells. European Journal of Immunology. 40: 2099-102. PMID 20853493 DOI: 10.1002/Eji.201040501 |
0.338 |
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| 2010 |
Tewari K, Flynn BJ, Boscardin SB, Kastenmueller K, Salazar AM, Anderson CA, Soundarapandian V, Ahumada A, Keler T, Hoffman SL, Nussenzweig MC, Steinman RM, Seder RA. Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates. Vaccine. 28: 7256-66. PMID 20846528 DOI: 10.1016/J.Vaccine.2010.08.098 |
0.373 |
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| 2010 |
Kamphorst AO, Guermonprez P, Dudziak D, Nussenzweig MC. Route of Antigen Uptake Differentially Impacts Presentation by Dendritic Cells and Activated Monocytes Journal of Immunology. 185: 3426-3435. PMID 20729332 DOI: 10.4049/Jimmunol.1001205 |
0.341 |
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| 2010 |
Pietzsch J, Scheid JF, Mouquet H, Klein F, Seaman MS, Jankovic M, Corti D, Lanzavecchia A, Nussenzweig MC. Human anti–HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness Journal of Experimental Medicine. 207: 1995-2002. PMID 20679402 DOI: 10.1084/Jem.20101176 |
0.409 |
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| 2010 |
Daniel JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen HT, Gazumyan A, Yamane A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC, et al. PTIP promotes chromatin changes critical for immunoglobulin class switch recombination Science. 329: 917-923. PMID 20671152 DOI: 10.1126/Science.1187942 |
0.37 |
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| 2010 |
Zhou T, Georgiev I, Wu X, Yang ZY, Dai K, Finzi A, Kwon YD, Scheid JF, Shi W, Xu L, Yang Y, Zhu J, Nussenzweig MC, Sodroski J, Shapiro L, et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science (New York, N.Y.). 329: 811-7. PMID 20616231 DOI: 10.1126/Science.1192819 |
0.393 |
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| 2010 |
Heidkamp GF, Neubert K, Haertel E, Nimmerjahn F, Nussenzweig MC, Dudziak D. Efficient generation of a monoclonal antibody against the human C-type lectin receptor DCIR by targeting murine dendritic cells. Immunology Letters. 132: 69-78. PMID 20566350 DOI: 10.1016/J.Imlet.2010.06.002 |
0.418 |
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| 2010 |
Stoyanov CT, Boscardin SB, Deroubaix S, Barba-Spaeth G, Franco D, Nussenzweig RS, Nussenzweig M, Rice CM. Immunogenicity and protective efficacy of a recombinant yellow fever vaccine against the murine malarial parasite Plasmodium yoelii Vaccine. 28: 4644-4652. PMID 20451637 DOI: 10.1016/J.Vaccine.2010.04.071 |
0.348 |
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| 2010 |
Santos MA, Huen MS, Jankovic M, Chen HT, López-Contreras AJ, Klein IA, Wong N, Barbancho JL, Fernandez-Capetillo O, Nussenzweig MC, Chen J, Nussenzweig A. Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8. The Journal of Experimental Medicine. 207: 973-81. PMID 20385748 DOI: 10.1084/Jem.20092308 |
0.304 |
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| 2010 |
Bunting SF, Callén E, Wong N, Chen HT, Polato F, Gunn A, Bothmer A, Feldhahn N, Fernandez-Capetillo O, Cao L, Xu X, Deng CX, Finkel T, Nussenzweig M, Stark JM, et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell. 141: 243-54. PMID 20362325 DOI: 10.1016/J.Cell.2010.03.012 |
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| 2010 |
Pietzsch J, Scheid JF, Mouquet H, Seaman MS, Broder CC, Nussenzweig MC. Anti-gp41 antibodies cloned from HIV-infected patients with broadly neutralizing serologic activity. Journal of Virology. 84: 5032-42. PMID 20219932 DOI: 10.1128/Jvi.00154-10 |
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| 2010 |
Liu K, Nussenzweig MC. Origin and development of dendritic cells. Immunological Reviews. 234: 45-54. PMID 20193011 DOI: 10.1111/J.0105-2896.2009.00879.X |
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| 2010 |
Boboila C, Yan C, Wesemann DR, Jankovic M, Wang JH, Manis J, Nussenzweig A, Nussenzweig M, Alt FW. Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4. The Journal of Experimental Medicine. 207: 417-27. PMID 20142431 DOI: 10.1084/Jem.20092449 |
0.388 |
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| 2010 |
Boboila C, Jankovic M, Yan CT, Wang JH, Wesemann DR, Zhang T, Fazeli A, Feldman L, Nussenzweig A, Nussenzweig M, Alt FW. Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70. Proceedings of the National Academy of Sciences of the United States of America. 107: 3034-9. PMID 20133803 DOI: 10.1073/Pnas.0915067107 |
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| 2010 |
Jankovic M, Robbiani DF, Dorsett Y, Eisenreich T, Xu Y, Tarakhovsky A, Nussenzweig A, Nussenzweig MC. Role of the translocation partner in protection against AID-dependent chromosomal translocations. Proceedings of the National Academy of Sciences of the United States of America. 107: 187-92. PMID 19966290 DOI: 10.1073/Pnas.0908946107 |
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| 2010 |
Richter S, Platzer B, Waltenberger D, Woisetschläger M, Strobl H, Nagy L, Sathe P, Corcoran L, Wu L, Shortman K, Sasaki I, Hoshino K, Hamada E, Hirashima T, Kaisho T, ... ... Nussenzweig M, et al. Dendritic cells: differentiation (WS-046) Chairpersons: Kayo Inaba, Laszlo Nagy International Immunology. 22. DOI: 10.1093/Intimm/Dxq310 |
0.303 |
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| 2009 |
Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Molecular Cell. 36: 631-41. PMID 19941823 DOI: 10.1016/J.Molcel.2009.11.007 |
0.397 |
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| 2009 |
Schwickert TA, Alabyev B, Manser T, Nussenzweig MC. Germinal center reutilization by newly activated B cells. The Journal of Experimental Medicine. 206: 2907-14. PMID 19934021 DOI: 10.1084/Jem.20091225 |
0.4 |
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| 2009 |
Bougnères L, Helft J, Tiwari S, Vargas P, Chang BH, Chan L, Campisi L, Lauvau G, Hugues S, Kumar P, Kamphorst AO, Dumenil AM, Nussenzweig M, MacMicking JD, Amigorena S, et al. A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells. Immunity. 31: 232-44. PMID 19699172 DOI: 10.1016/J.Immuni.2009.06.022 |
0.37 |
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| 2009 |
Darrasse-Jèze G, Deroubaix S, Mouquet H, Victora GD, Eisenreich T, Yao KH, Masilamani RF, Dustin ML, Rudensky A, Liu K, Nussenzweig MC. Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. The Journal of Experimental Medicine. 206: 1853-62. PMID 19667061 DOI: 10.1084/Jem.20090746 |
0.34 |
|
| 2009 |
Callén E, Jankovic M, Wong N, Zha S, Chen HT, Difilippantonio S, Di Virgilio M, Heidkamp G, Alt FW, Nussenzweig A, Nussenzweig M. Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes. Molecular Cell. 34: 285-97. PMID 19450527 DOI: 10.1016/J.Molcel.2009.04.025 |
0.318 |
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| 2009 |
Scheid JF, Mouquet H, Feldhahn N, Seaman MS, Velinzon K, Pietzsch J, Ott RG, Anthony RM, Zebroski H, Hurley A, Phogat A, Chakrabarti B, Li Y, Connors M, Pereyra F, ... ... Nussenzweig MC, et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature. 458: 636-40. PMID 19287373 DOI: 10.1038/Nature07930 |
0.436 |
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| 2009 |
Liu K, Victora GD, Schwickert TA, Guermonprez P, Meredith MM, Yao K, Chu FF, Randolph GJ, Rudensky AY, Nussenzweig M. In vivo analysis of dendritic cell development and homeostasis. Science (New York, N.Y.). 324: 392-7. PMID 19286519 DOI: 10.1126/Science.1170540 |
0.311 |
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| 2009 |
Scheid JF, Mouquet H, Feldhahn N, Walker BD, Pereyra F, Cutrell E, Seaman MS, Mascola JR, Wyatt RT, Wardemann H, Nussenzweig MC. A method for identification of HIV gp140 binding memory B cells in human blood. Journal of Immunological Methods. 343: 65-7. PMID 19100741 DOI: 10.1016/J.Jim.2008.11.012 |
0.402 |
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| 2008 |
Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell. 135: 1028-38. PMID 19070574 DOI: 10.1016/J.Cell.2008.09.062 |
0.331 |
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| 2008 |
Difilippantonio S, Gapud E, Wong N, Huang CY, Mahowald G, Chen HT, Kruhlak MJ, Callen E, Livak F, Nussenzweig MC, Sleckman BP, Nussenzweig A. 53BP1 facilitates long-range DNA end-joining during V(D)J recombination. Nature. 456: 529-33. PMID 18931658 DOI: 10.1038/Nature07476 |
0.349 |
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| 2008 |
McBride KM, Gazumyan A, Woo EM, Schwickert TA, Chait BT, Nussenzweig MC. Regulation of class switch recombination and somatic mutation by AID phosphorylation. The Journal of Experimental Medicine. 205: 2585-94. PMID 18838546 DOI: 10.1084/Jem.20081319 |
0.336 |
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| 2008 |
Mietzner B, Tsuiji M, Scheid J, Velinzon K, Tiller T, Abraham K, Gonzalez JB, Pascual V, Stichweh D, Wardemann H, Nussenzweig MC. Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors. Proceedings of the National Academy of Sciences of the United States of America. 105: 9727-32. PMID 18621685 DOI: 10.1073/Pnas.0803644105 |
0.357 |
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| 2008 |
Waskow C, Liu K, Darrasse-Jèze G, Guermonprez P, Ginhoux F, Merad M, Shengelia T, Yao K, Nussenzweig M. The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues. Nature Immunology. 9: 676-83. PMID 18469816 DOI: 10.1038/Ni.1615 |
0.308 |
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| 2008 |
Bulloch K, Miller MM, Gal-Toth J, Milner TA, Gottfried-Blackmore A, Waters EM, Kaunzner UW, Liu K, Lindquist R, Nussenzweig MC, Steinman RM, McEwen BS. CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain. The Journal of Comparative Neurology. 508: 687-710. PMID 18386786 DOI: 10.1002/Cne.21668 |
0.318 |
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| 2008 |
Nchinda G, Kuroiwa J, Oks M, Trumpfheller C, Park CG, Huang Y, Hannaman D, Schlesinger SJ, Mizenina O, Nussenzweig MC, Uberla K, Steinman RM. The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells. The Journal of Clinical Investigation. 118: 1427-36. PMID 18324335 DOI: 10.1172/Jci34224 |
0.353 |
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| 2008 |
Callén E, Nussenzweig MC, Nussenzweig A. Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly. Oncogene. 26: 7759-64. PMID 18066088 DOI: 10.1038/Sj.Onc.1210873 |
0.372 |
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| 2008 |
Pasqualucci L, Bhagat G, Jankovic M, Compagno M, Smith P, Muramatsu M, Honjo T, Morse HC, Nussenzweig MC, Dalla-Favera R. AID is required for germinal center-derived lymphomagenesis. Nature Genetics. 40: 108-12. PMID 18066064 DOI: 10.1038/Ng.2007.35 |
0.417 |
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| 2008 |
Tiller T, Meffre E, Yurasov S, Tsuiji M, Nussenzweig MC, Wardemann H. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning Journal of Immunological Methods. 329: 112-124. PMID 17996249 DOI: 10.1016/J.Jim.2007.09.017 |
0.427 |
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| 2008 |
Tiller T, Meffre E, Yurasov S, Tsuiji M, Nussenzweig MC, Wardemann H. Corrigendum to ‘Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning’[J. Immunol. Methods 329 (2008) 112−124] Journal of Immunological Methods. 334: 142. DOI: 10.1016/J.Jim.2008.02.010 |
0.396 |
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| 2007 |
Wardemann H, Nussenzweig MC. B-cell self-tolerance in humans. Advances in Immunology. 95: 83-110. PMID 17869611 DOI: 10.1016/S0065-2776(07)95003-8 |
0.438 |
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| 2007 |
Yurasov S, Nussenzweig MC. Regulation of autoreactive antibodies. Current Opinion in Rheumatology. 19: 421-426. PMID 17762605 DOI: 10.1097/Bor.0B013E328277Ef3B |
0.397 |
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| 2007 |
Dorsett Y, Robbiani DF, Jankovic M, Reina-San-Martin B, Eisenreich TR, Nussenzweig MC. A role for AID in chromosome translocations between c-myc and the IgH variable region. The Journal of Experimental Medicine. 204: 2225-32. PMID 17724134 DOI: 10.1084/Jem.20070884 |
0.364 |
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| 2007 |
Jankovic M, Nussenzweig A, Nussenzweig MC. Antigen receptor diversification and chromosome translocations. Nature Immunology. 8: 801-8. PMID 17641661 DOI: 10.1038/Ni1498 |
0.323 |
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| 2007 |
Skokos D, Shakhar G, Varma R, Waite JC, Cameron TO, Lindquist RL, Schwickert T, Nussenzweig MC, Dustin ML. Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes. Nature Immunology. 8: 835-44. PMID 17632517 DOI: 10.1038/Ni1490 |
0.331 |
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| 2007 |
Callén E, Jankovic M, Difilippantonio S, Daniel JA, Chen HT, Celeste A, Pellegrini M, McBride K, Wangsa D, Bredemeyer AL, Sleckman BP, Ried T, Nussenzweig M, Nussenzweig A. ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes Cell. 130: 63-75. PMID 17599403 DOI: 10.1016/J.Cell.2007.06.016 |
0.353 |
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| 2007 |
Ramiro A, Reina San-Martin B, McBride K, Jankovic M, Barreto V, Nussenzweig A, Nussenzweig MC. The role of activation-induced deaminase in antibody diversification and chromosome translocations. Advances in Immunology. 94: 75-107. PMID 17560272 DOI: 10.1016/S0065-2776(06)94003-6 |
0.391 |
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| 2007 |
Liu K, Waskow C, Liu X, Yao K, Hoh J, Nussenzweig M. Origin of dendritic cells in peripheral lymphoid organs of mice. Nature Immunology. 8: 578-83. PMID 17450143 DOI: 10.1038/Ni1462 |
0.317 |
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| 2007 |
Soares H, Waechter H, Glaichenhaus N, Mougneau E, Yagita H, Mizenina O, Dudziak D, Nussenzweig MC, Steinman RM. A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo. The Journal of Experimental Medicine. 204: 1095-106. PMID 17438065 DOI: 10.1084/Jem.20070176 |
0.325 |
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| 2007 |
Tiller T, Tsuiji M, Yurasov S, Velinzon K, Nussenzweig MC, Wardemann H. Autoreactivity in human IgG+ memory B cells. Immunity. 26: 205-213. PMID 17306569 DOI: 10.1016/J.Immuni.2007.01.009 |
0.407 |
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| 2007 |
Schwickert TA, Lindquist RL, Shakhar G, Livshits G, Skokos D, Kosco-Vilbois MH, Dustin ML, Nussenzweig MC. In vivo imaging of germinal centres reveals a dynamic open structure. Nature. 446: 83-7. PMID 17268470 DOI: 10.1038/Nature05573 |
0.439 |
|
| 2007 |
Bozzacco L, Trumpfheller C, Siegal FP, Mehandru S, Markowitz M, Carrington M, Nussenzweig MC, Piperno AG, Steinman RM. DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes. Proceedings of the National Academy of Sciences of the United States of America. 104: 1289-94. PMID 17229838 DOI: 10.1073/Pnas.0610383104 |
0.406 |
|
| 2007 |
Dudziak D, Kamphorst AO, Heidkamp GF, Buchholz VR, Trumpfheller C, Yamazaki S, Cheong C, Liu K, Lee HW, Park CG, Steinman RM, Nussenzweig MC. Differential antigen processing by dendritic cell subsets in vivo. Science (New York, N.Y.). 315: 107-11. PMID 17204652 DOI: 10.1126/Science.1136080 |
0.377 |
|
| 2007 |
Reina-San-Martin B, Chen J, Nussenzweig A, Nussenzweig MC. Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells. European Journal of Immunology. 37: 235-9. PMID 17183606 DOI: 10.1002/Eji.200636789 |
0.356 |
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| 2006 |
Kumar KA, Sano G, Boscardin S, Nussenzweig RS, Nussenzweig MC, Zavala F, Nussenzweig V. The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites. Nature. 444: 937-40. PMID 17151604 DOI: 10.1038/Nature05361 |
0.366 |
|
| 2006 |
Yurasov S, Tiller T, Tsuiji M, Velinzon K, Pascual V, Wardemann H, Nussenzweig MC. Persistent expression of autoantibodies in SLE patients in remission Journal of Experimental Medicine. 203: 2255-2261. PMID 16966430 DOI: 10.1084/Jem.20061446 |
0.391 |
|
| 2006 |
Ramiro AR, Nussenzweig MC, Nussenzweig A. Switching on chromosomal translocations. Cancer Research. 66: 7837-9. PMID 16912154 DOI: 10.1158/0008-5472.Can-06-0863 |
0.389 |
|
| 2006 |
Horsley V, O'Carroll D, Tooze R, Ohinata Y, Saitou M, Obukhanych T, Nussenzweig M, Tarakhovsky A, Fuchs E. Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell. 126: 597-609. PMID 16901790 DOI: 10.1016/J.Cell.2006.06.048 |
0.324 |
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| 2006 |
Gazumyan A, Reichlin A, Nussenzweig MC. Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization. The Journal of Experimental Medicine. 203: 1785-94. PMID 16818674 DOI: 10.1084/Jem.20060221 |
0.4 |
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| 2006 |
Germain RN, Miller MJ, Dustin ML, Nussenzweig MC. Dynamic imaging of the immune system: Progress, pitfalls and promise Nature Reviews Immunology. 6: 497-507. PMID 16799470 DOI: 10.1038/Nri1884 |
0.332 |
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| 2006 |
McBride KM, Gazumyan A, Woo EM, Barreto VM, Robbiani DF, Chait BT, Nussenzweig MC. Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 103: 8798-803. PMID 16723391 DOI: 10.1073/Pnas.0603272103 |
0.373 |
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| 2006 |
Trumpfheller C, Finke JS, López CB, Moran TM, Moltedo B, Soares H, Huang Y, Schlesinger SJ, Park CG, Nussenzweig MC, Granelli-Piperno A, Steinman RM. Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine. The Journal of Experimental Medicine. 203: 607-17. PMID 16505141 DOI: 10.1084/Jem.20052005 |
0.411 |
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| 2006 |
Boscardin SB, Hafalla JC, Masilamani RF, Kamphorst AO, Zebroski HA, Rai U, Morrot A, Zavala F, Steinman RM, Nussenzweig RS, Nussenzweig MC. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. The Journal of Experimental Medicine. 203: 599-606. PMID 16505139 DOI: 10.1084/Jem.20051639 |
0.419 |
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| 2006 |
Obukhanych TV, Nussenzweig MC. T-independent type II immune responses generate memory B cells Journal of Experimental Medicine. 203: 305-310. PMID 16476769 DOI: 10.1084/Jem.20052036 |
0.372 |
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| 2006 |
Tsuiji M, Yurasov S, Velinzon K, Thomas S, Nussenzweig MC, Wardemann H. A checkpoint for autoreactivity in human IgM+ memory B cell development. Journal of Experimental Medicine. 203: 393-400. PMID 16446381 DOI: 10.1084/Jem.20052033 |
0.397 |
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| 2006 |
Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature. 440: 105-9. PMID 16400328 DOI: 10.1038/Nature04495 |
0.357 |
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| 2005 |
Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, Boehmer Hv. Inducing and expanding regulatory T cell populations by foreign antigen. Nature Immunology. 6: 1219-1227. PMID 16244650 DOI: 10.1038/Ni1265 |
0.388 |
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| 2005 |
Barreto VM, Pan-Hammarstrom Q, Zhao Y, Hammarstrom L, Misulovin Z, Nussenzweig MC. AID from bony fish catalyzes class switch recombination Journal of Experimental Medicine. 202: 733-738. PMID 16157688 DOI: 10.1084/Jem.20051378 |
0.337 |
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| 2005 |
Difilippantonio S, Celeste A, Fernandez-Capetillo O, Chen HT, Reina San Martin B, Van Laethem F, Yang YP, Petukhova GV, Eckhaus M, Feigenbaum L, Manova K, Kruhlak M, Camerini-Otero RD, Sharan S, Nussenzweig M, et al. Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models. Nature Cell Biology. 7: 675-85. PMID 15965469 DOI: 10.1038/Ncb1270 |
0.358 |
|
| 2005 |
Ohinata Y, Payer B, O'Carroll D, Ancelin K, Ono Y, Sano M, Barton SC, Obukhanych T, Nussenzweig M, Tarakhovsky A, Saitou M, Surani MA. Blimp1 is a critical determinant of the germ cell lineage in mice Nature. 436: 207-213. PMID 15937476 DOI: 10.1038/Nature03813 |
0.366 |
|
| 2005 |
Steinman RM, Bonifaz L, Fujii S, Liu K, Bonnyay D, Yamazaki S, Pack M, Hawiger D, Iyoda T, Inaba K, Nussenzweig MC. The innate functions of dendritic cells in peripheral lymphoid tissues. Advances in Experimental Medicine and Biology. 560: 83-97. PMID 15932024 DOI: 10.1007/0-387-24180-9_12 |
0.317 |
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| 2005 |
Shakhar G, Lindquist RL, Skokos D, Dudziak D, Huang JH, Nussenzweig MC, Dustin ML. Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo Nature Immunology. 6: 707-714. PMID 15924144 DOI: 10.1038/Ni1210 |
0.377 |
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| 2005 |
Yurasov S, Wardemann H, Hammersen J, Tsuiji M, Meffre E, Pascual V, Nussenzweig MC. Defective B cell tolerance checkpoints in systemic lupus erythematosus Journal of Experimental Medicine. 201: 703-711. PMID 15738055 DOI: 10.1084/Jem.20042251 |
0.401 |
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| 2005 |
Reina-San-Martin B, Nussenzweig MC, Nussenzweig A, Difilippantonio S. Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1. Proceedings of the National Academy of Sciences of the United States of America. 102: 1590-5. PMID 15668392 DOI: 10.1073/Pnas.0406289102 |
0.387 |
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| 2005 |
Barreto VM, Ramiro AR, Nussenzweig MC. Activation-induced deaminase: controversies and open questions. Trends in Immunology. 26: 90-96. PMID 15668124 DOI: 10.1016/J.It.2004.12.004 |
0.332 |
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| 2004 |
Nussenzweig MC, Alt FW. Antibody diversity: one enzyme to rule them all. Nature Medicine. 10: 1304-5. PMID 15580255 DOI: 10.1038/Nm1204-1304 |
0.404 |
|
| 2004 |
Lindquist RL, Shakhar G, Dudziak D, Wardemann H, Eisenreich T, Dustin ML, Nussenzweig MC. Visualizing dendritic cell networks in vivo Nature Immunology. 5: 1243-1250. PMID 15543150 DOI: 10.1038/Ni1139 |
0.316 |
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| 2004 |
Reina-San-Martin B, Chen HT, Nussenzweig A, Nussenzweig MC. ATM is required for efficient recombination between immunoglobulin switch regions. The Journal of Experimental Medicine. 200: 1103-10. PMID 15520243 DOI: 10.1084/Jem.20041162 |
0.371 |
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| 2004 |
Ramiro AR, Nussenzweig MC. Immunology: aid for AID. Nature. 430: 980-981. PMID 15329709 DOI: 10.1038/430980B |
0.314 |
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| 2004 |
Wardemann H, Hammersen J, Nussenzweig MC. Human autoantibody silencing by immunoglobulin light chains Journal of Experimental Medicine. 200: 191-199. PMID 15263026 DOI: 10.1084/Jem.20040818 |
0.335 |
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| 2004 |
Boehmer Hv, Nussenzweig MC. The manipulation of immunity. Conference on from allergy to cancer: new perspectives for therapeutic vaccination. Embo Reports. 5: 766-771. PMID 15258616 DOI: 10.1038/Sj.Embor.7400204 |
0.359 |
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| 2004 |
Hawiger D, Masilamani RF, Bettelli E, Kuchroo VK, Nussenzweig MC. Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo. Immunity. 20: 695-705. PMID 15189735 DOI: 10.1016/J.Immuni.2004.05.002 |
0.376 |
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| 2004 |
Ward IM, Reina-San-Martin B, Olaru A, Minn K, Tamada K, Lau JS, Cascalho M, Chen L, Nussenzweig A, Livak F, Nussenzweig MC, Chen J. 53BP1 is required for class switch recombination. The Journal of Cell Biology. 165: 459-64. PMID 15159415 DOI: 10.1083/Jcb.200403021 |
0.347 |
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| 2004 |
McBride KM, Barreto V, Ramiro AR, Stavropoulos P, Nussenzweig MC. Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase. The Journal of Experimental Medicine. 199: 1235-44. PMID 15117971 DOI: 10.1084/Jem.20040373 |
0.371 |
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| 2004 |
Jankovic M, Casellas R, Yannoutsos N, Wardemann H, Nussenzweig MC. RAGs and Regulation of Autoantibodies Annual Review of Immunology. 22: 485-501. PMID 15032586 DOI: 10.1146/Annurev.Immunol.22.012703.104707 |
0.41 |
|
| 2004 |
Reichlin A, Gazumyan A, Nagaoka H, Kirsch KH, Kraus M, Rajewsky K, Nussenzweig MC. A B cell receptor with two Igalpha cytoplasmic domains supports development of mature but anergic B cells. The Journal of Experimental Medicine. 199: 855-65. PMID 15024049 DOI: 10.1084/Jem.20031140 |
0.404 |
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| 2004 |
Meffre E, Schaefer A, Wardemann H, Wilson P, Davis E, Nussenzweig MC. Surrogate Light Chain Expressing Human Peripheral B Cells Produce Self-reactive Antibodies Journal of Experimental Medicine. 199: 145-150. PMID 14699083 DOI: 10.1084/Jem.20031550 |
0.416 |
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| 2003 |
Han A, Saijo K, Mecklenbräuker I, Tarakhovsky A, Nussenzweig MC. Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival. Immunity. 19: 621-32. PMID 14563325 DOI: 10.1016/S1074-7613(03)00275-9 |
0.727 |
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| 2003 |
Barreto V, Reina-San-Martin B, Ramiro AR, McBride KM, Nussenzweig MC. C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. Molecular Cell. 12: 501-8. PMID 14536088 DOI: 10.1016/S1097-2765(03)00309-5 |
0.35 |
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| 2003 |
Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, Nussenzweig MC. Predominant autoantibody production by early human B cell precursors. Science (New York, N.Y.). 301: 1374-7. PMID 12920303 DOI: 10.1126/Science.1086907 |
0.42 |
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| 2003 |
Jankovic M, Nussenzweig MC. OcaB regulates transitional B cell selection International Immunology. 15: 1099-1104. PMID 12917262 DOI: 10.1093/Intimm/Dxg109 |
0.427 |
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| 2003 |
Reina-San-Martin B, Difilippantonio S, Hanitsch L, Masilamani RF, Nussenzweig A, Nussenzweig MC. H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation. The Journal of Experimental Medicine. 197: 1767-78. PMID 12810694 DOI: 10.1084/Jem.20030569 |
0.332 |
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| 2003 |
Ramiro AR, Stavropoulos P, Jankovic M, Nussenzweig MC. Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand Nature Immunology. 4: 452-456. PMID 12692548 DOI: 10.1038/Ni920 |
0.315 |
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| 2003 |
Steinman RM, Hawiger D, Nussenzweig MC. Tolerogenic dendritic cells. Annual Review of Immunology. 21: 685-711. PMID 12615891 DOI: 10.1146/Annurev.Immunol.21.120601.141040 |
0.396 |
|
| 2003 |
Guy-Grand D, Azogui O, Celli S, Darche S, Nussenzweig MC, Kourilsky P, Vassalli P. Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice. The Journal of Experimental Medicine. 197: 333-41. PMID 12566417 DOI: 10.1084/Jem.20021639 |
0.31 |
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| 2003 |
Lee SJ, Zheng N, Clavijo M, Nussenzweig MC. Normal Host Defense during Systemic Candidiasis in Mannose Receptor-Deficient Mice Infection and Immunity. 71: 437-445. PMID 12496194 DOI: 10.1128/Iai.71.1.437-445.2003 |
0.348 |
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| 2002 |
Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, Steinman RM. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. The Journal of Experimental Medicine. 196: 1627-38. PMID 12486105 DOI: 10.1084/Jem.20021598 |
0.385 |
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| 2002 |
Casellas R, Jankovic M, Meyer G, Gazumyan A, Luo Y, Roeder R, Nussenzweig M. OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin kappa genes. Cell. 110: 575-85. PMID 12230975 DOI: 10.1016/S0092-8674(02)00911-X |
0.323 |
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| 2002 |
Meffre E, Nussenzweig MC. Deletion of immunoglobulin β in developing B cells leads to cell death Proceedings of the National Academy of Sciences of the United States of America. 99: 11334-11339. PMID 12165571 DOI: 10.1073/Pnas.172369999 |
0.392 |
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| 2002 |
Pelanda R, Braun U, Hobeika E, Nussenzweig MC, Reth M. B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta. Journal of Immunology (Baltimore, Md. : 1950). 169: 865-72. PMID 12097390 DOI: 10.4049/Jimmunol.169.2.865 |
0.336 |
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| 2002 |
Shih TY, Meffre E, Roederer M, Nussenzweig MC. Role of BCR affinity in T cell–dependent antibody responses in vivo Nature Immunology. 3: 570-575. PMID 12021782 DOI: 10.1038/Ni803 |
0.438 |
|
| 2002 |
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, ... ... Nussenzweig MC, et al. Genomic instability in mice lacking histone H2AX. Science (New York, N.Y.). 296: 922-7. PMID 11934988 DOI: 10.1126/Science.1069398 |
0.303 |
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| 2002 |
Shih TY, Roederer M, Nussenzweig MC. Role of antigen receptor affinity in T cell-independent antibody responses in vivo. Nature Immunology. 3: 399-406. PMID 11896394 DOI: 10.1038/Ni776 |
0.427 |
|
| 2002 |
Steinman RM, Nussenzweig MC. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proceedings of the National Academy of Sciences of the United States of America. 99: 351-8. PMID 11773639 DOI: 10.1073/Pnas.231606698 |
0.379 |
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| 2001 |
Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsu M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, et al. AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching Nature. 414: 660-665. PMID 11740565 DOI: 10.1038/414660A |
0.342 |
|
| 2001 |
Wurbel MA, Malissen M, Guy-Grand D, Meffre E, Nussenzweig MC, Richelme M, Carrier A, Malissen B. Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gammadelta(+) gut intraepithelial lymphocytes. Blood. 98: 2626-32. PMID 11675330 DOI: 10.1182/Blood.V98.9.2626 |
0.391 |
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| 2001 |
Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, Ravetch JV, Steinman RM, Nussenzweig MC. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. The Journal of Experimental Medicine. 194: 769-79. PMID 11560993 DOI: 10.1084/Jem.194.6.769 |
0.408 |
|
| 2001 |
Meffre E, Milili M, Blanco-Betancourt C, Antunes H, Nussenzweig MC, Schiff C. Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development Journal of Clinical Investigation. 108: 879-886. PMID 11560957 DOI: 10.1172/Jci13051 |
0.396 |
|
| 2001 |
Yannoutsos N, Wilson P, Yu W, Chen HT, Nussenzweig A, Petrie H, Nussenzweig MC. The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo. The Journal of Experimental Medicine. 194: 471-80. PMID 11514603 DOI: 10.1084/Jem.194.4.471 |
0.307 |
|
| 2001 |
Kraus M, Pao LI, Reichlin A, Hu Y, Canono B, Cambier JC, Nussenzweig MC, Rajewsky K. Interference with immunoglobulin (Ig)α immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igβ cytoplasmic tail Journal of Experimental Medicine. 194: 455-469. PMID 11514602 DOI: 10.1084/Jem.194.4.455 |
0.404 |
|
| 2001 |
Meffre E, Chiorazzi M, Nussenzweig MC. Circulating Human B Cells That Express Surrogate Light Chains Display a Unique Antibody Repertoire Journal of Immunology. 167: 2151-2156. PMID 11489999 DOI: 10.4049/Jimmunol.167.4.2151 |
0.363 |
|
| 2001 |
Meffre E, Catalan N, Seltz F, Fischer A, Nussenzweig MC, Durandy A. Somatic hypermutation shapes the antibody repertoire of memory B cells in humans. Journal of Experimental Medicine. 194: 375-378. PMID 11489956 DOI: 10.1084/Jem.194.3.375 |
0.406 |
|
| 2001 |
Casellas R, Shih TA, Kleinewietfeld M, Rakonjac J, Nemazee D, Rajewsky K, Nussenzweig MC. Contribution of receptor editing to the antibody repertoire. Science (New York, N.Y.). 291: 1541-4. PMID 11222858 DOI: 10.1126/Science.1056600 |
0.415 |
|
| 2001 |
Reichlin A, Hu Y, Meffre E, Nagaoka H, Gong S, Kraus M, Rajewsky K, Nussenzweig MC. B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin β Journal of Experimental Medicine. 193: 13-23. PMID 11136817 DOI: 10.1084/Jem.193.1.13 |
0.347 |
|
| 2000 |
Meffre E, Casellas R, Nussenzweig MC. Antibody regulation of B cell development. Nature Immunology. 1: 379-385. PMID 11062496 DOI: 10.1038/80816 |
0.44 |
|
| 2000 |
Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, Nussenzweig M, Steinman RM. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. The Journal of Cell Biology. 151: 673-84. PMID 11062267 DOI: 10.1083/Jcb.151.3.673 |
0.36 |
|
| 2000 |
Guo M, Gong S, Maric S, Misulovin Z, Pack M, Mahnke K, Nussenzweig MC, Steinman RM. A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells. Human Immunology. 61: 729-38. PMID 10980384 DOI: 10.1016/S0198-8859(00)00144-0 |
0.401 |
|
| 2000 |
Meffre E, Davis E, Schiff C, Cunningham-Rundles C, Ivashkiv LB, Staudt LM, Young JW, Nussenzweig MC. Circulating human B cells that express surrogate light chains and edited receptors. Nature Immunology. 1: 207-13. PMID 10973277 DOI: 10.1038/79739 |
0.402 |
|
| 2000 |
Nagaoka H, Gonzalez-Aseguinolaza G, Tsuji M, Nussenzweig MC. Immunization and Infection Change the Number of Recombination Activating Gene (Rag)-Expressing B Cells in the Periphery by Altering Immature Lymphocyte Production Journal of Experimental Medicine. 191: 2113-2120. PMID 10859336 DOI: 10.1084/Jem.191.12.2113 |
0.412 |
|
| 2000 |
Kronin V, Wu L, Gong S, Nussenzweig MC, Shortman K. DEC-205 as a marker of dendritic cells with regulatory effects on CD8 T cell responses. International Immunology. 12: 731-735. PMID 10784619 DOI: 10.1093/Intimm/12.5.731 |
0.339 |
|
| 2000 |
Difilippantonio MJ, Zhu J, Chen HT, Meffre E, Nussenzweig MC, Max EE, Ried T, Nussenzweig A. DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation. Nature. 404: 510-4. PMID 10761921 DOI: 10.1038/35006670 |
0.327 |
|
| 2000 |
Leteux C, Chai W, Loveless RW, Yuen CT, Uhlin-Hansen L, Combarnous Y, Jankovic M, Maric SC, Misulovin Z, Nussenzweig MC, Feizi T. The cysteine-rich domain of the macrophage mannose receptor is a multispecific lectin that recognizes chondroitin sulfates A and B and sulfated oligosaccharides of blood group Lewis(a) and Lewis(x) types in addition to the sulfated N-glycans of lutropin. The Journal of Experimental Medicine. 191: 1117-26. PMID 10748230 DOI: 10.1084/Jem.191.7.1117 |
0.363 |
|
| 2000 |
Nagaoka H, Yu W, Nussenzweig MC. Regulation of RAG expression in developing lymphocytes. Current Opinion in Immunology. 12: 187-190. PMID 10712943 DOI: 10.1016/S0952-7915(99)00070-9 |
0.323 |
|
| 2000 |
Nussenzweig MC. Immunoglobulins and B cell development Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A487B |
0.369 |
|
| 1999 |
Yu W, Nagaoka H, Misulovin Z, Meffre E, Suh H, Jankovic M, Yannoutsos N, Casellas R, Besmer E, Papavasiliou F, Qin X, Nussenzweig MC. RAG expression in B cells in secondary lymphoid tissues. Cold Spring Harbor Symposia On Quantitative Biology. 64: 207-10. PMID 11232286 DOI: 10.1101/Sqb.1999.64.207 |
0.327 |
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| 1999 |
Yu W, Nagaoka H, Jankovic M, Misulovin Z, Suh H, Rolink A, Melchers F, Meffre E, Nussenzweig MC. Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization. Nature. 400: 682-7. PMID 10458165 DOI: 10.1038/23287 |
0.385 |
|
| 1999 |
Yu W, Misulovin Z, Suh H, Hardy RR, Jankovic M, Yannoutsos N, Nussenzweig MC. Coordinate Regulation of RAG1 and RAG2 by Cell Type-Specific DNA Elements 5' of RAG2 Science. 285: 1080-1084. PMID 10446057 DOI: 10.1126/Science.285.5430.1080 |
0.34 |
|
| 1999 |
Qin XF, Schwers S, Yu W, Papavasiliou F, Suh H, Nussenzweig A, Rajewsky K, Nussenzweig MC. Secondary V(D)J recombination in B-1 cells. Nature. 397: 355-9. PMID 9950428 DOI: 10.1038/16933 |
0.42 |
|
| 1998 |
Besmer E, Mansilla-Soto J, Cassard S, Sawchuk DJ, Brown G, Sadofsky M, Lewis SM, Nussenzweig MC, Cortes P. Hairpin coding end opening is mediated by RAG1 and RAG2 proteins. Molecular Cell. 2: 817-28. PMID 9885569 DOI: 10.1016/S1097-2765(00)80296-8 |
0.329 |
|
| 1998 |
Nussenzweig MC. Immune receptor editing: revise and select. Cell. 95: 875-878. PMID 9875841 DOI: 10.1016/S0092-8674(00)81711-0 |
0.365 |
|
| 1998 |
Qin XF, Reichlin A, Luo Y, Roeder RG, Nussenzweig MC. OCA-B integrates B cell antigen receptor-, CD40L- and IL 4-mediated signals for the germinal center pathway of B cell development. The Embo Journal. 17: 5066-75. PMID 9724642 DOI: 10.1093/Emboj/17.17.5066 |
0.392 |
|
| 1998 |
Meffre E, Papavasiliou F, Cohen P, de Bouteiller O, Bell D, Karasuyama H, Schiff C, Banchereau J, Liu YJ, Nussenzweig MC. Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells. The Journal of Experimental Medicine. 188: 765-72. PMID 9705958 DOI: 10.1084/Jem.188.4.765 |
0.411 |
|
| 1998 |
Casellas R, Nussenzweig A, Wuerffel R, Pelanda R, Reichlin A, Suh H, Qin XF, Besmer E, Kenter A, Rajewsky K, Nussenzweig MC. Ku80 is required for immunoglobulin isotype switching Embo Journal. 17: 2404-2411. PMID 9545251 DOI: 10.1093/Emboj/17.8.2404 |
0.403 |
|
| 1997 |
Lee SY, Reichlin A, Santana A, Sokol KA, Nussenzweig MC, Choi Y. TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival Immunity. 7: 703-713. PMID 9390693 DOI: 10.1016/S1074-7613(00)80390-8 |
0.3 |
|
| 1997 |
Weis-Garcia F, Besmer E, Sawchuk DJ, Yu W, Hu Y, Cassard S, Nussenzweig MC, Cortes P. V(D)J recombination: in vitro coding joint formation. Molecular and Cellular Biology. 17: 6379-85. PMID 9343399 DOI: 10.1128/Mcb.17.11.6379 |
0.343 |
|
| 1997 |
Papavasiliou F, Casellas R, Suh H, Qin XF, Besmer E, Pelanda R, Nemazee D, Rajewsky K, Nussenzweig MC. V(D)J recombination in mature B cells: a mechanism for altering antibody responses. Science (New York, N.Y.). 278: 298-301. PMID 9323210 DOI: 10.1126/Science.278.5336.298 |
0.42 |
|
| 1997 |
Ouyang H, Nussenzweig A, Kurimasa A, Soares VC, Li X, Cordon-Cardo C, Li Wh, Cheong N, Nussenzweig M, Iliakis G, Chen DJ, Li GC. Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo. The Journal of Experimental Medicine. 186: 921-9. PMID 9294146 DOI: 10.1084/Jem.186.6.921 |
0.359 |
|
| 1997 |
Nussenzweig MC. Immune responses: tails to teach a B cell. Current Biology. 7. PMID 9197224 DOI: 10.1016/S0960-9822(06)00173-4 |
0.399 |
|
| 1997 |
Sawchuk DJ, Weis-Garcia F, Malik S, Besmer E, Bustin M, Nussenzweig MC, Cortes P. V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins. The Journal of Experimental Medicine. 185: 2025-32. PMID 9166431 DOI: 10.1084/Jem.185.11.2025 |
0.355 |
|
| 1997 |
Papavasiliou F, Jankovic M, Gong S, Nussenzweig MC. Control of immunoglobulin gene rearrangements in developing B cells. Current Opinion in Immunology. 9: 233-8. PMID 9099793 DOI: 10.1016/S0952-7915(97)80141-0 |
0.345 |
|
| 1996 |
Gong S, Sanchez M, Nussenzweig MC. Counterselection against Dμ Is Mediated through Immunoglobulin (Ig)α-Igβ Journal of Experimental Medicine. 184: 2079-2084. PMID 8976164 DOI: 10.1084/Jem.184.6.2079 |
0.387 |
|
| 1996 |
Cortes P, Weis-Garcia F, Misulovin Z, Nussenzweig A, Lai JS, Li G, Nussenzweig MC, Baltimore D. In vitro V(D)J recombination: Signal joint formation Proceedings of the National Academy of Sciences of the United States of America. 93: 14008-14013. PMID 8943051 DOI: 10.1073/Pnas.93.24.14008 |
0.315 |
|
| 1996 |
Papavasiliou F, Jankovic M, Nussenzweig MC. Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition. The Journal of Experimental Medicine. 184: 2025-30. PMID 8920890 DOI: 10.1084/Jem.184.5.2025 |
0.324 |
|
| 1996 |
Kim U, Qin XF, Gong S, Stevens S, Luo Y, Nussenzweig M, Roeder RG. The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes. Nature. 383: 542-7. PMID 8849728 DOI: 10.1038/383542A0 |
0.407 |
|
| 1996 |
Nussenzweig A, Chen C, da Costa Soares V, Sanchez M, Sokol K, Nussenzweig MC, Li GC. Requirement for Ku80 in growth and immunoglobulin V(D)J recombination. Nature. 382: 551-5. PMID 8700231 DOI: 10.1038/382551A0 |
0.344 |
|
| 1996 |
Gong S, Nussenzweig MC. Regulation of an early developmental checkpoint in the B cell pathway by Igβ Science. 272: 411-414. PMID 8602530 DOI: 10.1126/Science.272.5260.411 |
0.375 |
|
| 1995 |
Heufler C, Humborg C, Steinman RM, Schuler G, Nussenzweig M. A molecular strategy to identify molecules that are specific for dendritic cells and/or critical to their unique immunostimulatory function. Advances in Experimental Medicine and Biology. 378: 367-9. PMID 8526095 DOI: 10.1007/978-1-4615-1971-3_82 |
0.331 |
|
| 1995 |
Inaba K, Swiggard WJ, Inaba M, Meltzer J, Mirza A, Sasagawa T, Nussenzweig MC, Steinman RM. Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. I. Expression on dendritic cells and other subsets of mouse leukocytes. Cellular Immunology. 163: 148-56. PMID 7758125 DOI: 10.1006/Cimm.1995.1109 |
0.422 |
|
| 1995 |
Jiang W, Swiggard WJ, Heufler C, Peng M, Mirza A, Steinman RM, Nussenzweig MC. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature. 375: 151-5. PMID 7753172 DOI: 10.1038/375151A0 |
0.429 |
|
| 1995 |
Papavasiliou F, Misulovin Z, Suh H, Nussenzweig MC. The role of Ig beta in precursor B cell transition and allelic exclusion. Science (New York, N.Y.). 268: 408-11. PMID 7716544 DOI: 10.1126/Science.7716544 |
0.394 |
|
| 1995 |
Papavasiliou F, Jankovic M, Suh H, Nussenzweig MC. The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion. The Journal of Experimental Medicine. 182: 1389-94. PMID 7595209 DOI: 10.1084/Jem.182.5.1389 |
0.373 |
|
| 1995 |
Swiggard WJ, Mirza A, Nussenzweig MC, Steinman RM. DEC-205, a 205-kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization, and N-terminal amino acid sequence. Cellular Immunology. 165: 302-11. PMID 7553896 DOI: 10.1006/Cimm.1995.1218 |
0.364 |
|
| 1994 |
Burkhardt AL, Costa T, Misulovin Z, Stealy B, Bolen JB, Nussenzweig MC. Ig alpha and Ig beta are functionally homologous to the signaling proteins of the T-cell receptor. Molecular and Cellular Biology. 14: 1095-1103. PMID 8289790 DOI: 10.1128/Mcb.14.2.1095 |
0.352 |
|
| 1994 |
Muta T, Kurosaki T, Misulovin Z, Sanchez M, Nussenzweig MC, Ravetch JV. Correction: A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling Nature. 369: 340-340. PMID 8183374 DOI: 10.1038/369340A0 |
0.34 |
|
| 1994 |
Muta T, Kurosaki T, Misulovin Z, Sanchez M, Nussenzweig MC, Ravetch JV. A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling Nature. 368: 70-73. PMID 8107887 DOI: 10.1038/368070A0 |
0.324 |
|
| 1994 |
Spanopoulou E, Roman CA, Corcoran LM, Schlissel MS, Silver DP, Nemazee D, Nussenzweig MC, Shinton SA, Hardy RR, Baltimore D. Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. Genes & Development. 8: 1030-42. PMID 7926785 DOI: 10.1101/Gad.8.9.1030 |
0.422 |
|
| 1994 |
Wayne J, Suh H, Misulovin Z, Sokol KA, Inaba K, Nussenzweig MC. A regulatory role for recombinase activating genes, RAG-1 and RAG-2, in T cell development Immunity. 1: 95-107. PMID 7534201 DOI: 10.1016/1074-7613(94)90103-1 |
0.376 |
|
| 1992 |
Costa TE, Franke RR, Sanchez M, Misulovin Z, Nussenzweig MC. Functional Reconstitution of an Immunoglobulin Antigen Receptor in T Cells Journal of Experimental Medicine. 175: 1669-1676. PMID 1588287 DOI: 10.1084/Jem.175.6.1669 |
0.42 |
|
| 1992 |
Costa TEF, Suh H, Nussenzweig MC. Chromosomal position of rearranging gene segments influences allelic exclusion in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 89: 2205-2208. PMID 1372438 DOI: 10.1073/Pnas.89.6.2205 |
0.341 |
|
| 1988 |
Nussenzweig MC, Schmidt EV, Shaw AC, Sinn E, Campos-Torres J, Mathey-Prevot B, Pattengale PK, Leder P. A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice. Nature. 336: 446-50. PMID 3143076 DOI: 10.1038/336446A0 |
0.356 |
|
| 1988 |
Nussenzweig MC, Shaw AC, Sinn E, Campos-Torres J, Leder P. Allelic exclusion in transgenic mice carrying mutant human IgM genes. The Journal of Experimental Medicine. 167: 1969-74. PMID 3133444 DOI: 10.1084/Jem.167.6.1969 |
0.31 |
|
| 1983 |
Steinman R, Gutchinov B, Witmer, Nussenzweig M. Dendritic cells are the principal stimulators of the primary mixed leukocyte reaction in mice Journal of Experimental Medicine. 157: 613-627. PMID 6185614 DOI: 10.1084/Jem.157.2.613 |
0.375 |
|
| 1982 |
Nussenzweig MC, Steinman RM, Witmer MD, Gutchinov B. A monoclonal antibody specific for mouse dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 161-5. PMID 6948298 DOI: 10.1073/Pnas.79.1.161 |
0.376 |
|
| 1982 |
Nussenzweig MC, Steinman RM. The cell surface of mouse lymphoid dendritic cells Immunology Today. 3: 65-68. DOI: 10.1016/S0167-5699(82)80036-4 |
0.379 |
|
| 1981 |
Nussenzweig MC, Steinman RM, Unkeless JC, Witmer MD, Gutchinov B, Cohn ZA. Studies of the cell surface of mouse dendritic cells and other leukocytes. The Journal of Experimental Medicine. 154: 168-87. PMID 7252426 DOI: 10.1084/Jem.154.1.168 |
0.373 |
|
| 1980 |
Nussenzweig MC, Steinman RM, Gutchinov B, Cohn ZA. Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes. The Journal of Experimental Medicine. 152: 1070-84. PMID 6968335 DOI: 10.1084/Jem.152.4.1070 |
0.383 |
|
| 1980 |
Steinman RM, Witmer MD, Nussenzweig MC, Chen LL, Schlesinger S, Cohn ZA. Dendritic cells of the mouse: identification and characterization. The Journal of Investigative Dermatology. 75: 14-6. PMID 6446582 DOI: 10.1111/1523-1747.Ep12521052 |
0.388 |
|
| 1980 |
Nussenzweig MC, Steinman RM. Contribution of dendritic cells to stimulation of the murine syngeneic mixed leukocyte reaction Journal of Experimental Medicine. 151: 1196-1212. PMID 6445399 DOI: 10.1084/Jem.151.5.1196 |
0.362 |
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