| Year |
Citation |
Score |
| 2024 |
Qin Q, Ramesh S, Li Z, Zhong L, Cherief M, Archer M, Xing X, Thottappillil N, Gomez-Salazar M, Xu M, Zhu M, Chang L, Uniyal A, Mazhar K, Mittal M, ... ... Clemens TL, et al. TrkA sensory neurons regulate osteosarcoma proliferation and vascularization to promote disease progression. Biorxiv : the Preprint Server For Biology. PMID 38979210 DOI: 10.1101/2024.06.20.599869 |
0.523 |
|
| 2022 |
Dirckx N, Zhang Q, Chu EY, Tower RJ, Li Z, Guo S, Yuan S, Khare PA, Zhang C, Verardo A, Alejandro LO, Park A, Faugere MC, Helfand SL, Somerman MJ, ... ... Clemens TL, et al. A specialized metabolic pathway partitions citrate in hydroxyapatite to impact mineralization of bones and teeth. Proceedings of the National Academy of Sciences of the United States of America. 119: e2212178119. PMID 36322718 DOI: 10.1073/pnas.2212178119 |
0.302 |
|
| 2021 |
Zhang Q, Mesner LD, Calabrese GM, Dirckx N, Li Z, Verardo A, Yang Q, Tower RJ, Faugere MC, Farber CR, Clemens TL. Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts. The Journal of Clinical Investigation. 131. PMID 33792563 DOI: 10.1172/JCI142580 |
0.323 |
|
| 2020 |
Meyers CA, Lee S, Sono T, Xu J, Negri S, Tian Y, Wang Y, Li Z, Miller S, Chang L, Gao Y, Minichiello L, Clemens TL, James AW. A Neurotrophic Mechanism Directs Sensory Nerve Transit in Cranial Bone. Cell Reports. 31: 107696. PMID 32460020 DOI: 10.1016/J.Celrep.2020.107696 |
0.307 |
|
| 2019 |
Dirckx N, Moorer MC, Clemens TL, Riddle RC. The role of osteoblasts in energy homeostasis. Nature Reviews. Endocrinology. PMID 31462768 DOI: 10.1038/S41574-019-0246-Y |
0.426 |
|
| 2019 |
Zhang Q, Riddle RC, Yang Q, Rosen CR, Guttridge DC, Dirckx N, Faugere MC, Farber CR, Clemens TL. The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage. Proceedings of the National Academy of Sciences of the United States of America. PMID 31434789 DOI: 10.1073/Pnas.1905489116 |
0.395 |
|
| 2019 |
Kim SP, Da H, Li Z, Kushwaha P, Beil C, Mei L, Xiong WC, Wolfgang MJ, Clemens TL, Riddle RC. Lrp4 expression by adipocytes and osteoblasts differentially impacts sclerostin's endocrine effects on body composition and glucose metabolism. The Journal of Biological Chemistry. PMID 30842262 DOI: 10.1074/Jbc.Ra118.006769 |
0.402 |
|
| 2018 |
Dirckx N, Tower RJ, Mercken EM, Vangoitsenhoven R, Moreau-Triby C, Breugelmans T, Nefyodova E, Cardoen R, Mathieu C, Van der Schueren B, Confavreux CB, Clemens TL, Maes C. Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism. The Journal of Clinical Investigation. 128: 1087-1105. PMID 29431735 DOI: 10.1172/Jci97794 |
0.346 |
|
| 2017 |
Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, et al. Erythropoietin stimulates murine and human Fibroblast growth factor-23, revealing novel roles for bone and bone marrow. Haematologica. PMID 28818868 DOI: 10.3324/Haematol.2017.167882 |
0.427 |
|
| 2017 |
Kim SP, Li Z, Zoch ML, Frey JL, Bowman CE, Kushwaha P, Ryan KA, Goh BC, Scafidi S, Pickett JE, Faugere MC, Kershaw EE, Thorek DLJ, Clemens TL, Wolfgang MJ, et al. Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner. Jci Insight. 2. PMID 28814665 DOI: 10.1172/Jci.Insight.92704 |
0.368 |
|
| 2017 |
Goh BC, Singhal V, Herrera AJ, Tomlinson RE, Kim S, Faugere MC, Germain-Lee EL, Clemens TL, Lee SJ, DiGirolamo DJ. Activin Receptor Type IIA (ACVR2A) Functions Directly in Osteoblasts as a Negative Regulator of Bone Mass. The Journal of Biological Chemistry. PMID 28659341 DOI: 10.1074/Jbc.M117.782128 |
0.451 |
|
| 2017 |
Tomlinson RE, Li Z, Li Z, Minichiello L, Riddle RC, Venkatesan A, Clemens TL. NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416686 DOI: 10.1073/Pnas.1701054114 |
0.378 |
|
| 2017 |
Riddle RC, Clemens TL. Bone Cell Bioenergetics and Skeletal Energy Homeostasis. Physiological Reviews. 97: 667-698. PMID 28202599 DOI: 10.1152/Physrev.00022.2016 |
0.363 |
|
| 2016 |
Li Z, Frey JL, Wong GW, Faugere MC, Wolfgang MJ, Kim JK, Riddle RC, Clemens TL. Glucose Transporter-4 Facilitates Insulin-stimulated Glucose Uptake in Osteoblasts. Endocrinology. en20161583. PMID 27689415 DOI: 10.1210/En.2016-1583 |
0.341 |
|
| 2016 |
Tomlinson RE, Li Z, Zhang Q, Goh BC, Li Z, Thorek DL, Rajbhandari L, Brushart TM, Minichiello L, Zhou F, Venkatesan A, Clemens TL. NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone. Cell Reports. PMID 27568565 DOI: 10.1016/J.Celrep.2016.08.002 |
0.377 |
|
| 2016 |
Zoch ML, Abou DS, Clemens TL, Thorek DL, Riddle RC. In vivo radiometric analysis of glucose uptake and distribution in mouse bone. Bone Research. 4: 16004. PMID 27088042 DOI: 10.1038/Boneres.2016.4 |
0.399 |
|
| 2016 |
Zoch ML, Clemens TL, Riddle RC. New insights into the biology of osteocalcin. Bone. 82: 42-9. PMID 26055108 DOI: 10.1016/J.Bone.2015.05.046 |
0.437 |
|
| 2015 |
Dewan AK, Tomlinson RE, Mitchell S, Goh BC, Yung RM, Kumar S, Tan EW, Faugere MC, Dietz HC, Clemens TL, Sponseller PD. Dysregulated TGF-β signaling alters bone microstructure in a mouse model of Loeys-Dietz syndrome. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 1447-54. PMID 26173585 DOI: 10.1002/Jor.22920 |
0.535 |
|
| 2015 |
Frey JL, Li Z, Ellis JM, Zhang Q, Farber CR, Aja S, Wolfgang MJ, Clemens TL, Riddle RC. Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast. Molecular and Cellular Biology. 35: 1979-91. PMID 25802278 DOI: 10.1128/Mcb.01343-14 |
0.407 |
|
| 2015 |
Zhang Q, Riddle RC, Clemens TL. Bone and the regulation of global energy balance. Journal of Internal Medicine. 277: 681-9. PMID 25597336 DOI: 10.1111/Joim.12348 |
0.448 |
|
| 2015 |
Kanazawa I, Canaff L, Abi Rafeh J, Angrula A, Li J, Riddle RC, Boraschi-Diaz I, Komarova SV, Clemens TL, Murshed M, Hendy GN. Osteoblast menin regulates bone mass in vivo. The Journal of Biological Chemistry. 290: 3910-24. PMID 25538250 DOI: 10.1074/Jbc.M114.629899 |
0.434 |
|
| 2014 |
Maes C, Clemens TL. Angiogenic-osteogenic coupling: the endothelial perspective. Bonekey Reports. 3: 578. PMID 25328674 DOI: 10.1038/Bonekey.2014.73 |
0.362 |
|
| 2014 |
Clemens TL. Vitamin B12 deficiency and bone health. The New England Journal of Medicine. 371: 963-4. PMID 25184870 DOI: 10.1056/Nejmcibr1407247 |
0.365 |
|
| 2014 |
Mesner LD, Ray B, Hsu YH, Manichaikul A, Lum E, Bryda EC, Rich SS, Rosen CJ, Criqui MH, Allison M, Budoff MJ, Clemens TL, Farber CR. Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density. The Journal of Clinical Investigation. 124: 2736-49. PMID 24789909 DOI: 10.1172/Jci73072 |
0.369 |
|
| 2014 |
Riddle RC, Clemens TL. Insulin, osteoblasts, and energy metabolism: why bone counts calories. The Journal of Clinical Investigation. 124: 1465-7. PMID 24642463 DOI: 10.1172/Jci75554 |
0.355 |
|
| 2014 |
Riddle RC, Frey JL, Tomlinson RE, Ferron M, Li Y, DiGirolamo DJ, Faugere MC, Hussain MA, Karsenty G, Clemens TL. Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis. Molecular and Cellular Biology. 34: 1850-62. PMID 24591652 DOI: 10.1128/Mcb.00075-14 |
0.42 |
|
| 2014 |
Farber CR, Reich A, Barnes AM, Becerra P, Rauch F, Cabral WA, Bae A, Quinlan A, Glorieux FH, Clemens TL, Marini JC. A novel IFITM5 mutation in severe atypical osteogenesis imperfecta type VI impairs Osteoblast production of pigment epithelium-derived factor Journal of Bone and Mineral Research. 29: 1402-1411. PMID 24519609 DOI: 10.1002/Jbmr.2173 |
0.402 |
|
| 2013 |
Farber CR, Clemens TL. Contemporary Approaches for Identifying Rare Bone Disease Causing Genes. Bone Research. 1: 301-310. PMID 25866697 DOI: 10.4248/Br201304001 |
0.345 |
|
| 2013 |
Riddle RC, Diegel CR, Leslie JM, Van Koevering KK, Faugere MC, Clemens TL, Williams BO. Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition. Plos One. 8: e63323. PMID 23675479 DOI: 10.1371/Journal.Pone.0063323 |
0.456 |
|
| 2013 |
Bonewald LF, Kiel DP, Clemens TL, Esser K, Orwoll ES, O'Keefe RJ, Fielding RA. Forum on bone and skeletal muscle interactions: summary of the proceedings of an ASBMR workshop. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1857-65. PMID 23671010 DOI: 10.1002/Jbmr.1980 |
0.364 |
|
| 2013 |
Stemmer K, Bielohuby M, Grayson BE, Begg DP, Chambers AP, Neff C, Woods SC, Erben RG, Tschöp MH, Bidlingmaier M, Clemens TL, Seeley RJ. Roux-en-Y gastric bypass surgery but not vertical sleeve gastrectomy decreases bone mass in male rats. Endocrinology. 154: 2015-24. PMID 23554454 DOI: 10.1210/En.2012-2130 |
0.353 |
|
| 2013 |
Bogan R, Riddle RC, Li Z, Kumar S, Nandal A, Faugere MC, Boskey A, Crawford SE, Clemens TL. A mouse model for human osteogenesis imperfecta type VI. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1531-6. PMID 23413146 DOI: 10.1002/Jbmr.1892 |
0.43 |
|
| 2013 |
Bilezikian JP, Bouillon R, Clemens T, Compston J, Bauer DC, Ebeling PR, Engelke K, Goltzman D, Guise T, Beur SMJD, Jüppner H, Lyons K, McCauley L, McClung MR, Miller PD, et al. Primer on the metabolic bone diseases and disorders of mineral metabolism. Journal of Bone and Joint Surgery-British Volume. 1087-1087. DOI: 10.1002/9781119266594 |
0.334 |
|
| 2012 |
Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT. Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell. 10: 259-72. PMID 22385654 DOI: 10.1016/J.Stem.2012.02.003 |
0.376 |
|
| 2012 |
Fulzele K, Clemens TL. Novel functions for insulin in bone. Bone. 50: 452-6. PMID 21723973 DOI: 10.1016/J.Bone.2011.06.018 |
0.365 |
|
| 2011 |
Riddle RC, Leslie JM, Gross TS, Clemens TL. Hypoxia-inducible factor-1α protein negatively regulates load-induced bone formation. The Journal of Biological Chemistry. 286: 44449-56. PMID 22081627 DOI: 10.1074/Jbc.M111.276683 |
0.378 |
|
| 2011 |
Yoshikawa Y, Kode A, Xu L, Mosialou I, Silva BC, Ferron M, Clemens TL, Economides AN, Kousteni S. Genetic evidence points to an osteocalcin-independent influence of osteoblasts on energy metabolism. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2012-25. PMID 21557308 DOI: 10.1002/Jbmr.417 |
0.332 |
|
| 2011 |
Clemens TL, Karsenty G. The osteoblast: an insulin target cell controlling glucose homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 677-80. PMID 21433069 DOI: 10.1002/Jbmr.321 |
0.398 |
|
| 2011 |
Wang Y, Cheng Z, Elalieh HZ, Nakamura E, Nguyen MT, Mackem S, Clemens TL, Bikle DD, Chang W. IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1437-46. PMID 21312270 DOI: 10.1002/Jbmr.359 |
0.338 |
|
| 2010 |
Mavalli MD, DiGirolamo DJ, Fan Y, Riddle RC, Campbell KS, van Groen T, Frank SJ, Sperling MA, Esser KA, Bamman MM, Clemens TL. Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice. The Journal of Clinical Investigation. 120: 4007-20. PMID 20921627 DOI: 10.1172/Jci42447 |
0.32 |
|
| 2010 |
Riddle RC, Lakhanpal A, Clemens TL. Roles of vessel growth factors in bone development and repair. Joint, Bone, Spine : Revue Du Rhumatisme. 77: 517-8. PMID 20851027 DOI: 10.1016/J.Jbspin.2010.08.007 |
0.394 |
|
| 2010 |
Fulzele K, Riddle RC, DiGirolamo DJ, Cao X, Wan C, Chen D, Faugere MC, Aja S, Hussain MA, Brüning JC, Clemens TL. Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell. 142: 309-19. PMID 20655471 DOI: 10.1016/J.Cell.2010.06.002 |
0.42 |
|
| 2010 |
Wan C, Shao J, Gilbert SR, Riddle RC, Long F, Johnson RS, Schipani E, Clemens TL. Role of HIF-1alpha in skeletal development. Annals of the New York Academy of Sciences. 1192: 322-6. PMID 20392254 DOI: 10.1111/J.1749-6632.2009.05238.X |
0.406 |
|
| 2010 |
Qiu T, Wu X, Zhang F, Clemens TL, Wan M, Cao X. TGF-beta type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling. Nature Cell Biology. 12: 224-34. PMID 20139972 DOI: 10.1038/Ncb2022 |
0.452 |
|
| 2010 |
Gan Y, Zhang Y, Digirolamo DJ, Jiang J, Wang X, Cao X, Zinn KR, Carbone DP, Clemens TL, Frank SJ. Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling. Molecular Endocrinology (Baltimore, Md.). 24: 644-56. PMID 20133448 DOI: 10.1210/Me.2009-0357 |
0.315 |
|
| 2010 |
Kumar S, Wan C, Ramaswamy G, Clemens TL, Ponnazhagan S. Mesenchymal stem cells expressing osteogenic and angiogenic factors synergistically enhance bone formation in a mouse model of segmental bone defect. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1026-34. PMID 20068549 DOI: 10.1038/Mt.2009.315 |
0.436 |
|
| 2010 |
Weinstein RS, Wan C, Liu Q, Wang Y, Almeida M, O'Brien CA, Thostenson J, Roberson PK, Boskey AL, Clemens TL, Manolagas SC. Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice Aging Cell. 9: 147-161. PMID 20047574 DOI: 10.1111/J.1474-9726.2009.00545.X |
0.43 |
|
| 2010 |
DeMambro VE, Kawai M, Clemens TL, Fulzele K, Maynard JA, Marín de Evsikova C, Johnson KR, Canalis E, Beamer WG, Rosen CJ, Donahue LR. A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis. The Journal of Endocrinology. 204: 241-53. PMID 20032200 DOI: 10.1677/Joe-09-0328 |
0.405 |
|
| 2010 |
Shomento SH, Wan C, Cao X, Faugere MC, Bouxsein ML, Clemens TL, Riddle RC. Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development. Journal of Cellular Biochemistry. 109: 196-204. PMID 19899108 DOI: 10.1002/Jcb.22396 |
0.354 |
|
| 2010 |
Riddle RC, Lakhanpal A, Clemens TL. Roles of vascular growth factors in bone development and repair | Rôles des facteurs de croissance vasculaires dans le développement et la réparation des os Revue Du Rhumatisme (Edition Francaise). 77: A33-A35. DOI: 10.1016/J.Rhum.2010.07.003 |
0.312 |
|
| 2009 |
Fan Y, Menon RK, Cohen P, Hwang D, Clemens T, DiGirolamo DJ, Kopchick JJ, Le Roith D, Trucco M, Sperling MA. Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism. The Journal of Biological Chemistry. 284: 19937-44. PMID 19460757 DOI: 10.1074/Jbc.M109.014308 |
0.37 |
|
| 2009 |
Riddle RC, Khatri R, Schipani E, Clemens TL. Role of hypoxia-inducible factor-1alpha in angiogenic-osteogenic coupling. Journal of Molecular Medicine (Berlin, Germany). 87: 583-90. PMID 19415227 DOI: 10.1007/S00109-009-0477-9 |
0.399 |
|
| 2009 |
Shen X, Wan C, Ramaswamy G, Mavalli M, Wang Y, Duvall CL, Deng LF, Guldberg RE, Eberhart A, Clemens TL, Gilbert SR. Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 1298-305. PMID 19338032 DOI: 10.1002/Jor.20886 |
0.338 |
|
| 2009 |
Zhang F, Qiu T, Wu X, Wan C, Shi W, Wang Y, Chen JG, Wan M, Clemens TL, Cao X. Sustained BMP signaling in osteoblasts stimulates bone formation by promoting angiogenesis and osteoblast differentiation Journal of Bone and Mineral Research. 24: 1224-1233. PMID 19257813 DOI: 10.1359/Jbmr.090204 |
0.46 |
|
| 2009 |
Chiang C, Chiu M, Moore AJ, Anderson PH, Ghasem-Zadeh A, McManus JF, Ma C, Seeman E, Clemens TL, Morris HA, Zajac JD, Davey RA. Mineralization and bone resorption are regulated by the androgen receptor in male mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 621-31. PMID 19049333 DOI: 10.1359/Jbmr.081217 |
0.442 |
|
| 2009 |
Horiuchi N, Hongo T, Clemens TL. The synthetic human parathyroid hormone‐related protein is inhibited by a parathyroid hormone antagonist in rats in vivo Journal of Bone and Mineral Research. 5: 541-545. PMID 2166420 DOI: 10.1002/Jbmr.5650050603 |
0.31 |
|
| 2009 |
Epstein S, Clemens TL, Kaplan FF. The American Society for Bone and Mineral Research: normal or increased remodelling? Journal of Bone and Mineral Research. 7: 251-252. PMID 1585825 DOI: 10.1002/Jbmr.5650070302 |
0.372 |
|
| 2008 |
Mak KK, Bi Y, Wan C, Chuang PT, Clemens T, Young M, Yang Y. Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression. Developmental Cell. 14: 674-88. PMID 18477451 DOI: 10.1016/J.Devcel.2008.02.003 |
0.443 |
|
| 2008 |
Jacobsen KA, Al-Aql ZS, Wan C, Fitch JL, Stapleton SN, Mason ZD, Cole RM, Gilbert SR, Clemens TL, Morgan EF, Einhorn TA, Gerstenfeld LC. Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 596-609. PMID 18433297 DOI: 10.1359/Jbmr.080103 |
0.413 |
|
| 2008 |
Wan C, Gilbert SR, Wang Y, Cao X, Shen X, Ramaswamy G, Jacobsen KA, Alaql ZS, Eberhardt AW, Gerstenfeld LC, Einhorn TA, Deng L, Clemens TL. Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration. Proceedings of the National Academy of Sciences of the United States of America. 105: 686-91. PMID 18184809 DOI: 10.1073/Pnas.0708474105 |
0.396 |
|
| 2007 |
Wang Y, Wan C, Gilbert SR, Clemens TL. Oxygen sensing and osteogenesis. Annals of the New York Academy of Sciences. 1117: 1-11. PMID 18056033 DOI: 10.1196/Annals.1402.049 |
0.422 |
|
| 2007 |
Yeo H, Beck LH, Thompson SR, Farach-Carson MC, McDonald JM, Clemens TL, Zayzafoon M. Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption. The Journal of Biological Chemistry. 282: 35318-27. PMID 17884821 DOI: 10.1074/Jbc.M702435200 |
0.427 |
|
| 2007 |
DiGirolamo DJ, Mukherjee A, Fulzele K, Gan Y, Cao X, Frank SJ, Clemens TL. Mode of growth hormone action in osteoblasts. The Journal of Biological Chemistry. 282: 31666-74. PMID 17698843 DOI: 10.1074/Jbc.M705219200 |
0.37 |
|
| 2007 |
Fulzele K, DiGirolamo DJ, Liu Z, Xu J, Messina JL, Clemens TL. Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action. The Journal of Biological Chemistry. 282: 25649-58. PMID 17553792 DOI: 10.1074/Jbc.M700651200 |
0.339 |
|
| 2007 |
Wang Y, Wan C, Deng L, Liu X, Cao X, Gilbert SR, Bouxsein ML, Faugere MC, Guldberg RE, Gerstenfeld LC, Haase VH, Johnson RS, Schipani E, Clemens TL. The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. The Journal of Clinical Investigation. 117: 1616-26. PMID 17549257 DOI: 10.1172/Jci31581 |
0.418 |
|
| 2007 |
Wang Y, Nishida S, Boudignon BM, Burghardt A, Elalieh HZ, Hamilton MM, Majumdar S, Halloran BP, Clemens TL, Bikle DD. IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1329-37. PMID 17539737 DOI: 10.1359/Jbmr.070517 |
0.453 |
|
| 2007 |
Liu X, Bruxvoort KJ, Zylstra CR, Liu J, Cichowski R, Faugere MC, Bouxsein ML, Wan C, Williams BO, Clemens TL. Lifelong accumulation of bone in mice lacking Pten in osteoblasts. Proceedings of the National Academy of Sciences of the United States of America. 104: 2259-64. PMID 17287359 DOI: 10.1073/Pnas.0604153104 |
0.437 |
|
| 2006 |
Xu J, Liu Z, Clemens TL, Messina JL. Insulin reverses growth hormone-induced homologous desensitization. The Journal of Biological Chemistry. 281: 21594-606. PMID 16717097 DOI: 10.1074/Jbc.M513612200 |
0.303 |
|
| 2006 |
Liu Z, Tang Y, Qiu T, Cao X, Clemens TL. A dishevelled-1/Smad1 interaction couples WNT and bone morphogenetic protein signaling pathways in uncommitted bone marrow stromal cells. The Journal of Biological Chemistry. 281: 17156-63. PMID 16621789 DOI: 10.1074/Jbc.M513812200 |
0.392 |
|
| 2005 |
Robins JC, Akeno N, Mukherjee A, Dalal RR, Aronow BJ, Koopman P, Clemens TL. Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone. 37: 313-22. PMID 16023419 DOI: 10.1016/J.Bone.2005.04.040 |
0.337 |
|
| 2005 |
Mukherjee A, Dong SS, Clemens T, Alvarez J, Serra R. Co-ordination of TGF-beta and FGF signaling pathways in bone organ cultures. Mechanisms of Development. 122: 557-71. PMID 15804568 DOI: 10.1016/J.Mod.2004.11.006 |
0.332 |
|
| 2005 |
Holmen SL, Zylstra CR, Mukherjee A, Sigler RE, Faugere MC, Bouxsein ML, Deng L, Clemens TL, Williams BO. Essential role of beta-catenin in postnatal bone acquisition. The Journal of Biological Chemistry. 280: 21162-8. PMID 15802266 DOI: 10.1074/Jbc.M501900200 |
0.403 |
|
| 2005 |
Rutter MM, Markoff E, Clayton L, Akeno N, Zhao G, Clemens TL, Chernausek SD. Osteoblast-specific expression of insulin-like growth factor-1 in bone of transgenic mice induces insulin-like growth factor binding protein-5. Bone. 36: 224-31. PMID 15780948 DOI: 10.1016/J.Bone.2004.10.005 |
0.453 |
|
| 2004 |
Carvalho RS, Einhorn TA, Lehmann W, Edgar C, Al-Yamani A, Apazidis A, Pacicca D, Clemens TL, Gerstenfeld LC. The role of angiogenesis in a murine tibial model of distraction osteogenesis Bone. 34: 849-861. PMID 15121017 DOI: 10.1016/J.Bone.2003.12.027 |
0.301 |
|
| 2003 |
Zhang M, Faugere MC, Malluche H, Rosen CJ, Chernausek SD, Clemens TL. Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 836-43. PMID 12733722 DOI: 10.1359/jbmr.2003.18.5.836 |
0.346 |
|
| 2002 |
Zhang M, Xuan S, Bouxsein ML, von Stechow D, Akeno N, Faugere MC, Malluche H, Zhao G, Rosen CJ, Efstratiadis A, Clemens TL. Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. The Journal of Biological Chemistry. 277: 44005-12. PMID 12215457 DOI: 10.1074/Jbc.M208265200 |
0.453 |
|
| 2000 |
Zhao G, Monier-Faugere MC, Langub MC, Geng Z, Nakayama T, Pike JW, Chernausek SD, Rosen CJ, Donahue LR, Malluche HH, Fagin JA, Clemens TL. Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation. Endocrinology. 141: 2674-82. PMID 10875273 DOI: 10.1210/Endo.141.7.7585 |
0.439 |
|
| 1998 |
Tam VK, Clemens TL, Green J. The effect of cell-matrix interaction on parathyroid hormone (PTH) receptor binding and PTH responsiveness in proximal renal tubular cells and osteoblast-like cells. Endocrinology. 139: 3072-80. PMID 9645678 DOI: 10.1210/Endo.139.7.6089 |
0.316 |
|
| 1997 |
Shane E, Parisien M, Henderson JE, Dempster DW, Feldman F, Hardy MA, Tohme JF, Karaplis AC, Clemens TL. Tumor-induced osteomalacia: Clinical and basic studies Journal of Bone and Mineral Research. 12: 1502-1511. PMID 9286768 DOI: 10.1359/Jbmr.1997.12.9.1502 |
0.311 |
|
| 1996 |
Prystowsky JH, Muzio PJ, Sevran S, Clemens TL. Effect of UVB phototherapy and oral calcitriol (1,25-dihydroxyvitamin D3) on vitamin D photosynthesis in patients with psoriasis Journal of the American Academy of Dermatology. 35: 690-695. PMID 8912562 DOI: 10.1016/S0190-9622(96)90722-7 |
0.314 |
|
| 1996 |
Vu D, Ong JM, Clemens T, Kern PA. 1,25-Dihydroxyvitamin D induces lipoprotein lipase expression in 3T3-L1 cells in association with adipocyte differentiation Endocrinology. 137: 1540-1544. PMID 8612483 DOI: 10.1210/Endo.137.5.8612483 |
0.377 |
|
| 1994 |
Adams JS, Ren SY, Arbelle JE, Clemens TL, Shany S. A role for nitric oxide in the regulated expression of the 25-hydroxy-vitamin D-1-hydroxylation reaction in the chick myelomonocytic cell line HD-11. Endocrinology. 134: 499-502. PMID 8275965 DOI: 10.1210/Endo.134.1.8275965 |
0.302 |
|
| 1994 |
Adams JS, Ren SY, Arbelle JE, Horiuchi N, Gray RW, Clemens TL, Shany S. Regulated production and intracrine action of 1,25-dihydroxyvitamin D3 in the chick myelomonocytic cell line HD-11 Endocrinology. 134: 2567-2573. PMID 8194484 DOI: 10.1210/Endo.134.6.8194484 |
0.337 |
|
| 1994 |
Okano K, Wu S, Huang X, Pirola CJ, Juppner H, Abou-Samra AB, Segre GV, Iwasaki K, Fagin JA, Clemens TL. Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleic acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells: cell-specific regulation by angiotensin-II and PTHrP. Endocrinology. 135: 1093-1099. PMID 8070351 DOI: 10.1210/Endo.135.3.8070351 |
0.314 |
|
| 1993 |
Wu S, Pirola CJ, Green J, Yamaguchi DT, Okano K, Jueppner H, Forrester JS, Fagin JA, Clemens TL. Effects of N-terminal, midregion, and C-terminal parathyroid hormone-related peptides on adenosine 3′,5′-monophosphate and cytoplasmic free calcium in rat aortic smooth muscle cells and UMR-106 osteoblast-like cells Endocrinology. 133: 2437-2444. PMID 8243262 DOI: 10.1210/Endo.133.6.8243262 |
0.3 |
|
| 1991 |
Meier DE, Luckey MM, Wallenstein S, Clemens TL, Orwoll ES, Waslien CI. Calcium, Vitamin D, and Parathyroid Hormone Status in Young White and Black Women: Association with Racial Differences in Bone Mass The Journal of Clinical Endocrinology and Metabolism. 72: 703-710. PMID 1997523 DOI: 10.1210/Jcem-72-3-703 |
0.416 |
|
| 1990 |
Himmelstein S, Clemens T, Rubin A, Lindsay R. Vitamin D supplementation in elderly nursing home residents increases 25(OH)D but not 1,25(OH)2D. The American Journal of Clinical Nutrition. 52: 701-706. PMID 2403063 DOI: 10.1093/Ajcn/52.4.701 |
0.347 |
|
| 1990 |
Silverberg SJ, Shane E, Jacobs TP, Siris ES, Gartenberg F, Seldin D, Clemens TL, Bilezikian JP. Nephrolithiasis and bone involvement in primary hyperparathyroidism. The American Journal of Medicine. 89: 327-34. PMID 2393037 DOI: 10.1016/0002-9343(90)90346-F |
0.421 |
|
| 1990 |
Adams JS, Beeker TG, Hongo T, Clemens TL. Constitutive expression of a vitamin D 1-hydroxylase in a myelomonocytic cell line: A model for studying 1,25-dihydroxyvitamin D production in vitro Journal of Bone and Mineral Research. 5: 1265-1269. PMID 1963733 DOI: 10.1002/Jbmr.5650051212 |
0.328 |
|
| 1989 |
Clemens TL, McGlade SA, Garrett KP, Craviso GL, Hendy GN. Extracellular Calcium Modulates Vitamin D-Dependent Calbindin-D28K Gene Expression In Chick Kidney Cells Endocrinology. 124: 1582-1584. PMID 2917526 DOI: 10.1210/Endo-124-3-1582 |
0.315 |
|
| 1988 |
Clemens TL, Garrett KP, Zhou XY, Pike JW, Haussler MR, Dempster DW. Immunocytochemical localization of the 1,25-dihydroxyvitamin D3 receptor in target cells Endocrinology. 122: 1224-1230. PMID 2831024 DOI: 10.1210/Endo-122-4-1224 |
0.351 |
|
| 1987 |
Siris ES, Clemens TL, Dempster DW, Shane E, Segre GV, Lindsay R, Bilezikian JP. Tumor-induced osteomalacia. Kinetics of calcium, phosphorus, and vitamin D metabolism and characteristics of bone histomorphometry The American Journal of Medicine. 82: 307-312. PMID 3812526 DOI: 10.1016/0002-9343(87)90075-1 |
0.398 |
|
| 1987 |
Craviso GL, Garrett KP, Clemens TL. 1,25-Dihydroxyvitamin D3 induces the synthesis of vitamin D-dependent calcium-binding protein in cultured chick kidney cells. Endocrinology. 120: 894-902. PMID 3026790 DOI: 10.1210/Endo-120-3-894 |
0.337 |
|
| 1986 |
Clemens TL, Zhou XY, Myles M, Endres D, Lindsay R. Serum vitamin D2 and vitamin D3 metabolite concentrations and absorption of vitamin D2 in elderly subjects. The Journal of Clinical Endocrinology and Metabolism. 63: 656-60. PMID 3488327 DOI: 10.1210/Jcem-63-3-656 |
0.308 |
|
| 1986 |
Zhou XY, Dempster DW, Marion SL, Pike JW, Haussler MR, Clemens TL. Bone vitamin D-dependent calcium-binding protein is localized in chondrocytes of growth-plate cartilage Calcified Tissue International. 38: 244-247. PMID 3085904 DOI: 10.1007/Bf02556718 |
0.444 |
|
| 1985 |
Lo CW, Paris PW, Clemens TL, Nolan J, Holick MF. Vitamin D absorption in healthy subjects and in patients with intestinal malabsorption syndromes The American Journal of Clinical Nutrition. 42: 644-649. PMID 4050723 DOI: 10.1093/Ajcn/42.4.644 |
0.304 |
|
| 1984 |
Amento EP, Bhalla AK, Kurnick JT, Kradin RL, Clemens T, Holick SA, Holick MF, Krane SM. 1 alpha,25-dihydroxyvitamin D3 induces maturation of the human monocyte cell line U937, and, in association with a factor from human T lymphocytes, augments production of the monokine, mononuclear cell factor. Journal of Clinical Investigation. 73: 731-739. PMID 6608530 DOI: 10.1172/Jci111266 |
0.319 |
|
| 1983 |
Clemens TL, Adams JS, Horiuchi N, Gilchrest BA, Cho H, Tsuchiya Y, Matsuo N, Suda T, Holick MF. Interaction of 1,25-Dihydroxyvitamin-D3 with Keratinocytes and Fibroblasts from Skin of Normal Subjects and a Subject with Vitamin-D-Dependent Rickets, Type II: A Model for Study of the Mode of Action of 1,25-Dihydroxyvitamin D3* The Journal of Clinical Endocrinology and Metabolism. 56: 824-830. PMID 6300167 DOI: 10.1210/Jcem-56-4-824 |
0.308 |
|
| 1982 |
Cunningham J, Fraher LJ, Clemens TL, Revell PA, Papapoulos SE. Chronic acidosis with metabolic bone disease: Effect of alkali on bone morphology and vitamin D metabolism The American Journal of Medicine. 73: 199-204. PMID 7114077 DOI: 10.1016/0002-9343(82)90179-6 |
0.361 |
|
| 1982 |
Adams JS, Clemens TL, Parrish JA, Holick MF. Vitamin-D synthesis and metabolism after ultraviolet irradiation of normal and vitamin-D-deficient subjects New England Journal of Medicine. 306: 722-725. PMID 7038486 DOI: 10.1056/Nejm198203253061206 |
0.316 |
|
| 1982 |
Adami S, Frijlink WB, Bijvoet OLM, O'Riordan JLH, Clemens TL, Papapoulos SE. Regulation of calcium absorption by 1,25,dihydroxy-vitamin D--studies of the effects of a bisphosphonate treatment Calcified Tissue International. 34: 317-320. PMID 6814718 DOI: 10.1007/Bf02411260 |
0.33 |
|
| 1980 |
Pavlovitch H, Clemens T, Laouari D, O'Riordan JL, Balsan S. Lack of effect of ovariectomy on the metabolism of vitamin D and intestinal calcium-binding protein in female rats Journal of Endocrinology. 86: 419-424. PMID 7430901 DOI: 10.1677/Joe.0.0860419 |
0.329 |
|
| 1980 |
Papapoulos SE, Clemens TL, Fraher LJ, Gleed J, O'Riordan JLH. Metabolites Of Vitamin D In Human Vitamin-D Deficiency: Effect Of Vitamin D3 Or 1,25-Dihydroxycholecalciferol The Lancet. 316: 612-615. PMID 6107407 DOI: 10.1016/S0140-6736(80)90283-4 |
0.323 |
|
| 1980 |
Cundy F, Kanis JA, Heynen G, Earnshaw M, Clemens TL, O'Riordan JLH, Merritt AL, Compston JE. Lack of Direct Effect of 1,25-Dihydroxy-Vitamin D3 on Mineralization of Bone and Secretion of Parathyroid Hormone Clinical Science. 59: 15P-15P. DOI: 10.1042/CS059015P |
0.335 |
|
| 1979 |
Papapoulos SE, Clemens TL, Fraher LJ, Lewin IG, Sandler LM, O'Riordan JL. 1, 25-dihydroxycholecalciferol in the pathogenesis of the hypercalcaemia of sarcoidosis. Lancet. 1: 627-30. PMID 85869 DOI: 10.1016/S0140-6736(79)91076-6 |
0.306 |
|
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