Year |
Citation |
Score |
2024 |
Neo DM, Clatworthy AE, Hung DT. A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in . Journal of Bacteriology. e0033523. PMID 38319218 DOI: 10.1128/jb.00335-23 |
0.586 |
|
2024 |
Sturm A, Sun P, Avila-Pacheco J, Clatworthy AE, Bloom-Ackermann Z, Wuo MG, Gomez JE, Jin S, Clish CB, Kiessling LL, Hung DT. Genetic factors affecting storage and utilization of lipids during dormancy in . Mbio. e0320823. PMID 38236034 DOI: 10.1128/mbio.03208-23 |
0.569 |
|
2023 |
Parada-Kusz M, Clatworthy AE, Goering ER, Blackwood SM, Salm EJ, Choi C, Combs S, Lee JSW, Rodriguez-Osorio C, Tomita S, Hung DT. A tryptophan metabolite modulates the host response to bacterial infection via kainate receptors. Biorxiv : the Preprint Server For Biology. PMID 37645903 DOI: 10.1101/2023.08.16.553532 |
0.586 |
|
2022 |
Warrier T, Romano KP, Clatworthy AE, Hung DT. Integrated genomics and chemical biology herald an era of sophisticated antibacterial discovery, from defining essential genes to target elucidation. Cell Chemical Biology. 29: 716-729. PMID 35523184 DOI: 10.1016/j.chembiol.2022.04.006 |
0.583 |
|
2022 |
Poulsen BE, Clatworthy AE, Hung DT. The Use of Tn-Seq and the FiTnEss Analysis to Define the Core Essential Genome of Pseudomonas aeruginosa. Methods in Molecular Biology (Clifton, N.J.). 2377: 179-197. PMID 34709617 DOI: 10.1007/978-1-0716-1720-5_10 |
0.527 |
|
2020 |
Ernst CM, Braxton JR, Rodriguez-Osorio CA, Zagieboylo AP, Li L, Pironti A, Manson AL, Nair AV, Benson M, Cummins K, Clatworthy AE, Earl AM, Cosimi LA, Hung DT. Author Correction: Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae. Nature Medicine. PMID 32587394 DOI: 10.1038/S41591-020-0974-5 |
0.545 |
|
2020 |
Ernst CM, Braxton JR, Rodriguez-Osorio CA, Zagieboylo AP, Li L, Pironti A, Manson AL, Nair AV, Benson M, Cummins K, Clatworthy AE, Earl AM, Cosimi LA, Hung DT. Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae. Nature Medicine. PMID 32284589 DOI: 10.1038/S41591-020-0825-4 |
0.601 |
|
2019 |
Poulsen BE, Yang R, Clatworthy AE, White T, Osmulski SJ, Li L, Penaranda C, Lander ES, Shoresh N, Hung DT. Defining the core essential genome of . Proceedings of the National Academy of Sciences of the United States of America. PMID 31036669 DOI: 10.1073/Pnas.1900570116 |
0.586 |
|
2018 |
Parada-Kusz M, Penaranda C, Hagedorn EJ, Clatworthy A, Nair AV, Henninger JE, Ernst C, Li B, Riquelme R, Jijon H, Villablanca EJ, Zon LI, Hung D, Allende ML. Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies. Disease Models & Mechanisms. PMID 30266803 DOI: 10.1242/Dmm.034876 |
0.553 |
|
2018 |
Clatworthy AE, Romano KP, Hung DT. Whole-organism phenotypic screening for anti-infectives promoting host health. Nature Chemical Biology. PMID 29556098 DOI: 10.1038/S41589-018-0018-3 |
0.628 |
|
2017 |
Wellington S, Nag PP, Michalska K, Johnston SE, Jedrzejczak RP, Kaushik VK, Clatworthy AE, Siddiqi N, McCarren P, Bajrami B, Maltseva NI, Combs S, Fisher SL, Joachimiak A, Schreiber SL, et al. A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase. Nature Chemical Biology. PMID 28671682 DOI: 10.1038/Nchembio.2420 |
0.58 |
|
2014 |
Slater LH, Clatworthy AE, Hung DT. Bacterial toxins and small molecules elucidate endosomal trafficking. Trends in Microbiology. 22: 53-5. PMID 24370463 DOI: 10.1016/J.Tim.2013.12.002 |
0.582 |
|
2013 |
Stanley SA, Kawate T, Iwase N, Shimizu M, Clatworthy AE, Kazyanskaya E, Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S, Aquadro JA, Grant SS, Rubin EJ, Hung DT. Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32. Proceedings of the National Academy of Sciences of the United States of America. 110: 11565-70. PMID 23798446 DOI: 10.1073/Pnas.1302114110 |
0.603 |
|
2013 |
Slater LH, Hett EC, Clatworthy AE, Mark KG, Hung DT. CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 9932-7. PMID 23716698 DOI: 10.1073/Pnas.1302257110 |
0.588 |
|
2012 |
Chand NS, Clatworthy AE, Hung DT. The two-component sensor KinB acts as a phosphatase to regulate Pseudomonas aeruginosa Virulence. Journal of Bacteriology. 194: 6537-47. PMID 23024348 DOI: 10.1128/Jb.01168-12 |
0.574 |
|
2011 |
Chand NS, Lee JS, Clatworthy AE, Golas AJ, Smith RS, Hung DT. The sensor kinase KinB regulates virulence in acute Pseudomonas aeruginosa infection. Journal of Bacteriology. 193: 2989-99. PMID 21515773 DOI: 10.1128/Jb.01546-10 |
0.571 |
|
2011 |
Gomez JE, Clatworthy A, Hung DT. Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches. Critical Reviews in Biochemistry and Molecular Biology. 46: 41-66. PMID 21250782 DOI: 10.3109/10409238.2010.538663 |
0.584 |
|
2009 |
Clatworthy AE, Lee JS, Leibman M, Kostun Z, Davidson AJ, Hung DT. Pseudomonas aeruginosa infection of zebrafish involves both host and pathogen determinants. Infection and Immunity. 77: 1293-303. PMID 19168742 DOI: 10.1128/Iai.01181-08 |
0.614 |
|
2007 |
Clatworthy AE, Pierson E, Hung DT. Targeting virulence: A new paradigm for antimicrobial therapy Nature Chemical Biology. 3: 541-548. PMID 17710100 DOI: 10.1038/Nchembio.2007.24 |
0.619 |
|
2005 |
Clatworthy AE, Valencia-Burton MA, Haber JE, Oettinger MA. The MRE11-RAD50-XRS2 complex, in addition to other non-homologous end-joining factors, is required for V(D)J joining in yeast Journal of Biological Chemistry. 280: 20247-20252. PMID 15757898 DOI: 10.1074/Jbc.M500126200 |
0.624 |
|
2003 |
Clatworthy AE, Valencia MA, Haber JE, Oettinger MA. V(D)J recombination and RAG-mediated transposition in yeast Molecular Cell. 12: 489-499. PMID 14536087 DOI: 10.1016/S1097-2765(03)00305-8 |
0.626 |
|
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