Shigeki Miyamoto - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Molecular Biology, Cell Biology, Immunology

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Romero N, Wuerzberger-Davis SM, Van Waesberghe C, Jansens RJ, Tishchenko A, Verhamme R, Miyamoto S, Favoreel HW. Correction for Romero et al., "Pseudorabies Virus Infection Results in a Broad Inhibition of Host Gene Transcription". Journal of Virology. 97: e0129223. PMID 37811995 DOI: 10.1128/jvi.01292-23  0.688
2023 Chang HY, Huynh M, Roopra AS, Callander NS, Miyamoto S. HAPLN1 matrikine: A bone marrow homing factor linked to poor MM patient outcomes. Blood Advances. PMID 37647592 DOI: 10.1182/bloodadvances.2023010139  0.344
2023 Romero N, Tishchenko A, Verhamme R, Wuerzberger-Davis SM, Van Waesberghe C, Nauwynck HJ, Miyamoto S, Favoreel HW. Several Alphaherpesviruses Interact Similarly with the NF-κB Pathway and Suppress NF-κB-Dependent Gene Expression. Microbiology Spectrum. 11: e0142123. PMID 37466427 DOI: 10.1128/spectrum.01421-23  0.793
2022 De Bakshi D, Chen YC, Wuerzberger-Davis SM, Ma M, Waters BJ, Li L, Suzuki A, Miyamoto S. Ectopic CH60 mediates HAPLN1-induced cell survival signaling in multiple myeloma. Life Science Alliance. 6. PMID 36625202 DOI: 10.26508/lsa.202201636  0.76
2022 Romero N, Wuerzberger-Davis SM, Van Waesberghe C, Jansens RJ, Tishchenko A, Verhamme R, Miyamoto S, Favoreel HW. Correction for Romero et al., "Pseudorabies Virus Infection Results in a Broad Inhibition of Host Gene Transcription". Journal of Virology. e0106722. PMID 35916543 DOI: 10.1128/jvi.01067-22  0.688
2022 Romero N, Wuerzberger-Davis SM, Van Waesberghe C, Jansens RJ, Tishchenko A, Verhamme R, Miyamoto S, Favoreel HW. Pseudorabies Virus Infection Results in a Broad Inhibition of Host Gene Transcription. Journal of Virology. 96: e0071422. PMID 35730976 DOI: 10.1128/jvi.00714-22  0.779
2022 Mark C, Warrick J, Callander NS, Hematti P, Miyamoto S. A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance. Molecular Cancer Research : McR. PMID 35604822 DOI: 10.1158/1541-7786.MCR-21-0941  0.404
2021 Wu ZH, Miyamoto S. Analyze the SUMOylation of IKK γ/NEMO During Genotoxic Stress. Methods in Molecular Biology (Clifton, N.J.). 2366: 183-190. PMID 34236639 DOI: 10.1007/978-1-0716-1669-7_11  0.329
2020 Zhang JZ, Nguyen AH, Miyamoto S, Heller Brown J, McCulloch AD, Zhang J. Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling. Plos Biology. 18: e3000866. PMID 32881857 DOI: 10.1371/Journal.Pbio.3000866  0.435
2020 Lisiero DN, Cheng Z, Tejera MM, Neldner BT, Warrick JW, Wuerzberger-Davis SM, Hoffmann A, Suresh M, Miyamoto S. IκBα Nuclear Export Enables 4-1BB-Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 32817348 DOI: 10.4049/Jimmunol.2000039  0.723
2020 Marruecos L, Bertran J, Guillén Y, González J, Batlle R, López-Arribillaga E, Garrido M, Ruiz-Herguido C, Lisiero D, González-Farré M, Arce-Gallego S, Iglesias M, Nebreda AR, Miyamoto S, Bigas A, et al. IκBα deficiency imposes a fetal phenotype to intestinal stem cells. Embo Reports. e49708. PMID 32270911 DOI: 10.15252/Embr.201949708  0.383
2020 Chaim OM, Miki S, Ma J, Flores A, Miyamoto S, Furnari F, Brown JH. Regulation of glioblastoma tumor growth and stem cell properties through Gα12: an upstream player in YAP signaling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06682  0.3
2019 Babaei M, Liu Y, Wuerzberger-Davis SM, McCaslin EZ, DiRusso CJ, Yeo AT, Kagermazova L, Miyamoto S, Gilmore TD. CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein. Plos One. 14: e0222588. PMID 31553754 DOI: 10.1371/Journal.Pone.0222588  0.799
2019 Lung DK, Warrick JW, Hematti P, Callander NS, Mark CJ, Miyamoto S, Alarid ET. Bone marrow stromal cells transcriptionally repress ESR1 but cannot overcome constitutive ESR1 mutant activity. Endocrinology. PMID 31504407 DOI: 10.1210/En.2019-00299  0.389
2019 Suetomi T, Miyamoto S, Brown JH. Inflammation in non-ischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31441689 DOI: 10.1152/Ajpheart.00223.2019  0.415
2019 Byun J, Del Re DP, Zhai P, Ikeda S, Shirakabe A, Mizushima W, Miyamoto S, Brown JH, Sadoshima J. Yes-Associated Protein (YAP) mediates adaptive cardiac hypertrophy in response to pressure overload. The Journal of Biological Chemistry. PMID 30635403 DOI: 10.1074/Jbc.Ra118.006123  0.319
2018 Suetomi T, Willeford A, Brand CS, Cho Y, Ross RS, Miyamoto S, Brown JH. Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca/Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling. Circulation. 138: 2530-2544. PMID 30571348 DOI: 10.1161/Circulationaha.118.034621  0.323
2018 Brand CS, Tan VP, Brown JH, Miyamoto S. RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes. Cellular Signalling. PMID 29953931 DOI: 10.1016/J.Cellsig.2018.06.012  0.371
2018 Willeford A, Suetomi T, Nickle A, Hoffman HM, Miyamoto S, Heller Brown J. CaMKIIδ-mediated inflammatory gene expression and inflammasome activation in cardiomyocytes initiate inflammation and induce fibrosis. Jci Insight. 3. PMID 29925681 DOI: 10.1172/Jci.Insight.97054  0.383
2018 Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH. YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity. Oncogene. PMID 29887596 DOI: 10.1038/S41388-018-0301-5  0.447
2017 Huynh M, Pak C, Markovina S, Callander NS, Chng KS, Wuerzberger-Davis SM, Bakshi DD, Kink JA, Hematti P, Hope C, Asimakopoulos F, Rui L, Miyamoto S. Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma. The Journal of Biological Chemistry. PMID 29279332 DOI: 10.1074/Jbc.Ra117.000667  0.842
2017 Hope C, Emmerich PB, Papadas A, Pagenkopf A, Matkowskyj KA, Van De Hey DR, Payne SN, Clipson L, Callander NS, Hematti P, Miyamoto S, Johnson MG, Deming DA, Asimakopoulos F. Versican-Derived Matrikines Regulate Batf3-Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer. Journal of Immunology (Baltimore, Md. : 1950). PMID 28754680 DOI: 10.4049/Jimmunol.1700529  0.323
2017 Xiong X, Wen YA, Mitov MI, C Oaks M, Miyamoto S, Gao T. PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells. Cell Death Discovery. 3: 16103. PMID 28179998 DOI: 10.1038/Cddiscovery.2016.103  0.327
2017 Gray CB, Suetomi T, Xiang S, Blackwood EA, Glembotski CC, Miyamoto S, Daan Westenbrink B, Brown JH. CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α. Journal of Molecular and Cellular Cardiology. PMID 28077321 DOI: 10.1016/J.Yjmcc.2017.01.002  0.452
2017 Deming DA, Hope C, Emmerich P, Pagenkopf A, Matkowskyj K, Van DeHey D, Payne S, Clipson L, Callander NS, Hematti P, Miyamoto S, Johnson MG, Asimakopoulos F. Versican proteolysis as a key regulator of CD8+ T-cell infiltration in colorectal cancer. Journal of Clinical Oncology. 35: e15082-e15082. DOI: 10.1200/Jco.2017.35.15_Suppl.E15082  0.309
2016 Zhu F, Hwang B, Miyamoto S, Rui L. Nuclear Import of JAK1 is Mediated by a Classical NLS and is Required for Survival of Diffuse Large B-cell Lymphoma. Molecular Cancer Research : McR. PMID 28031410 DOI: 10.1158/1541-7786.Mcr-16-0344  0.464
2016 Hope C, Foulcer S, Jagodinsky J, Chen SX, Jensen JL, Patel S, Leith C, Maroulakou I, Callander N, Miyamoto S, Hematti P, Apte SS, Asimakopoulos F. Immunoregulatory roles of versican proteolysis in the myeloma microenvironment. Blood. PMID 27259980 DOI: 10.1182/Blood-2016-03-705780  0.44
2016 Li Y, Bouchlaka MN, Wolff J, Grindle KM, Lu L, Qian S, Zhong X, Pflum N, Jobin P, Kahl BS, Eickhoff JC, Wuerzberger-Davis SM, Miyamoto S, Thomas CJ, Yang DT, et al. FBXO10 deficiency and BTK activation upregulate BCL2 expression in mantle cell lymphoma. Oncogene. PMID 27157620 DOI: 10.1038/Onc.2016.155  0.766
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Miyamoto S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.305
2016 Tan VP, Miyamoto S. Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals. Journal of Molecular and Cellular Cardiology. 95: 31-41. PMID 26773603 DOI: 10.1016/J.Yjmcc.2016.01.005  0.338
2015 Yu O, Miyamoto S, Brown JH. MRTF-A and YAP exert dual control in GPCR and RhoA-mediated transcriptional regulation and cell proliferation. Molecular and Cellular Biology. PMID 26459764 DOI: 10.1128/Mcb.00772-15  0.411
2015 Hwang B, McCool K, Wan J, Wuerzberger-Davis SM, Young EW, Choi EY, Cingolani G, Weaver BA, Miyamoto S. IPO3 mediated nonclassical nuclear import of NEMO drives DNA damage-dependent NF-κB activation. The Journal of Biological Chemistry. PMID 26060253 DOI: 10.1074/Jbc.M115.645960  0.838
2015 Helzer KT, Hooper C, Miyamoto S, Alarid ET. Ubiquitylation of nuclear receptors: new linkages and therapeutic implications. Journal of Molecular Endocrinology. 54: R151-67. PMID 25943391 DOI: 10.1530/Jme-14-0308  0.31
2015 Jensen JL, Rakhmilevich A, Heninger E, Broman AT, Hope C, Phan F, Miyamoto S, Maroulakou I, Callander N, Hematti P, Chesi M, Bergsagel PL, Sondel P, Asimakopoulos F. Tumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple Myeloma. Cancer Immunology Research. PMID 25941352 DOI: 10.1158/2326-6066.Cir-15-0025-T  0.413
2015 Lee Y, Kubli DA, Hanna RA, Cortez MQ, Lee HY, Miyamoto S, Gustafsson ÅB. Cellular redox status determines sensitivity to BNIP3-mediated cell death in cardiac myocytes. American Journal of Physiology. Cell Physiology. 308: C983-92. PMID 25810259 DOI: 10.1152/Ajpcell.00273.2014  0.352
2015 Hwang B, Phan FP, McCool K, Choi EY, You J, Johnson A, Audhya A, Miyamoto S. Quantification of cellular NEMO content and its impact on NF-κB activation by genotoxic stress. Plos One. 10: e0116374. PMID 25742655 DOI: 10.1371/Journal.Pone.0116374  0.837
2015 Jackson SS, Miyamoto S. Dissecting NF-κB signaling induced by genotoxic agents via genetic complementation of NEMO-deficient 1.3E2 cells. Methods in Molecular Biology (Clifton, N.J.). 1280: 197-215. PMID 25736750 DOI: 10.1007/978-1-4939-2422-6_11  0.575
2015 Roberts DJ, Miyamoto S. Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy Cell Death and Differentiation. 22: 248-257. PMID 25323588 DOI: 10.1038/Cdd.2014.173  0.32
2015 Jackson SS, Oberley C, Hooper CP, Grindle K, Wuerzberger-Davis S, Wolff J, McCool K, Rui L, Miyamoto S. Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling. Experimental Cell Research. 331: 58-72. PMID 25304104 DOI: 10.1016/J.Yexcr.2014.09.034  0.846
2015 Li Y, Bouchlaka MN, Grindle K, Kahl BS, Miyamoto S, Yang DT, Capitini CM, Rui L. Synergistic Co-Targeting of BTK and BCL2 in Mantle Cell Lymphoma Blood. 126: 708-708. DOI: 10.1182/Blood.V126.23.708.708  0.447
2014 Hooper C, Jackson SS, Coughlin EE, Coon JJ, Miyamoto S. Covalent modification of the NF-κB essential modulator (NEMO) by a chemical compound can regulate its ubiquitin binding properties in vitro. The Journal of Biological Chemistry. 289: 33161-74. PMID 25296760 DOI: 10.1074/Jbc.M114.582478  0.398
2014 Hsu KT, Yu XM, Audhya AW, Jaume JC, Lloyd RV, Miyamoto S, Prolla TA, Chen H. Novel approaches in anaplastic thyroid cancer therapy. The Oncologist. 19: 1148-55. PMID 25260367 DOI: 10.1634/Theoncologist.2014-0182  0.337
2014 Callander N, Markovina S, Eickhoff J, Hutson P, Campbell T, Hematti P, Go R, Hegeman R, Longo W, Williams E, Asimakopoulos F, Miyamoto S. Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network. Cancer Chemotherapy and Pharmacology. 74: 875-82. PMID 25168296 DOI: 10.1007/S00280-014-2550-5  0.658
2014 Zhao X, Ding EY, Yu OM, Xiang SY, Tan-Sah VP, Yung BS, Hedgpeth J, Neubig RR, Lau LF, Brown JH, Miyamoto S. Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. Journal of Molecular and Cellular Cardiology. 75: 152-61. PMID 25106095 DOI: 10.1016/J.Yjmcc.2014.07.017  0.409
2014 Shin EM, Hay HS, Lee MH, Goh JN, Tan TZ, Sen YP, Lim SW, Yousef EM, Ong HT, Thike AA, Kong X, Wu Z, Mendoz E, Sun W, Salto-Tellez M, ... ... Miyamoto S, et al. DEAD-box helicase DP103 defines metastatic potential of human breast cancers. The Journal of Clinical Investigation. 124: 3807-24. PMID 25083991 DOI: 10.1172/Jci73451  0.382
2014 Hope C, Ollar SJ, Heninger E, Hebron E, Jensen JL, Kim J, Maroulakou I, Miyamoto S, Leith C, Yang DT, Callander N, Hematti P, Chesi M, Bergsagel PL, Asimakopoulos F. TPL2 kinase regulates the inflammatory milieu of the myeloma niche. Blood. 123: 3305-15. PMID 24723682 DOI: 10.1182/Blood-2014-02-554071  0.396
2014 Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger-Davis SM, Lee MH, Svaren J, Miyamoto S, Jarrard DF. A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-κB activation. Plos One. 9: e88052. PMID 24558376 DOI: 10.1371/Journal.Pone.0088052  0.796
2014 Fahl WE, Wuerzberger-Davis S, Miyamoto S. Abstract 32: Suppression of medical radiation DNA damage in cancer susceptible and normal humans using a new aminothiol radioprotector Cancer Research. 74: 32-32. DOI: 10.1158/1538-7445.Cansusc14-32  0.72
2014 Hope C, Ollar SJ, Heninger E, Jensen JL, Hebron E, Kim J, Maroulakou I, Miyamoto S, Callander N, Hematti P, Chesi M, Bergsagel PL, Asimakopoulos F. Abstract 1169: TPL2 kinase regulates the inflammatory milieu of the myeloma niche Cancer Research. 74: 1169-1169. DOI: 10.1158/1538-7445.Am2014-1169  0.391
2013 Xiang SY, Ouyang K, Yung BS, Miyamoto S, Smrcka AV, Chen J, Brown JH. PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart Science Signaling. 6. PMID 24345679 DOI: 10.1126/Scisignal.2004405  0.385
2013 Jackson SS, Coughlin EE, Coon JJ, Miyamoto S. Identifying post-translational modifications of NEMO by tandem mass spectrometry after high affinity purification. Protein Expression and Purification. 92: 48-53. PMID 24012789 DOI: 10.1016/J.Pep.2013.08.020  0.535
2013 Mulero MC, Ferres-Marco D, Islam A, Margalef P, Pecoraro M, Toll A, Drechsel N, Charneco C, Davis S, Bellora N, Gallardo F, López-Arribillaga E, Asensio-Juan E, Rodilla V, González J, ... ... Miyamoto S, et al. Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer. Cancer Cell. 24: 151-66. PMID 23850221 DOI: 10.1016/J.Ccr.2013.06.003  0.46
2013 Thomas RL, Roberts DJ, Kubli DA, Lee Y, Quinsay MN, Owens JB, Fischer KM, Sussman MA, Miyamoto S, Gustafsson ÅB. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes & Development. 27: 1365-77. PMID 23788623 DOI: 10.1101/Gad.215871.113  0.318
2013 Pak C, Miyamoto S. A new alpha in line between KRAS and NF-κB activation? Cancer Discovery. 3: 613-615. PMID 23749528 DOI: 10.1158/2159-8290.Cd-13-0193  0.448
2013 Hebron E, Hope C, Kim J, Jensen JL, Flanagan C, Bhatia N, Maroulakou I, Mitsiades C, Miyamoto S, Callander N, Hematti P, Asimakopoulos F. MAP3K8 kinase regulates myeloma growth by cell-autonomous and non-autonomous mechanisms involving myeloma-associated monocytes/macrophages. British Journal of Haematology. 160: 779-84. PMID 23252623 DOI: 10.1111/Bjh.12175  0.468
2012 McCool KW, Miyamoto S. DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out. Immunological Reviews. 246: 311-26. PMID 22435563 DOI: 10.1111/J.1600-065X.2012.01101.X  0.837
2012 Young EW, Pak C, Kahl BS, Yang DT, Callander NS, Miyamoto S, Beebe DJ. Microscale functional cytomics for studying hematologic cancers. Blood. 119: e76-85. PMID 22262772 DOI: 10.1182/Blood-2011-10-384347  0.394
2012 Humbert AT, Cook R, McFarland T, Go R, Markovina S, Miyamoto S, Williams EC, Asimakopoulos F, Kolesar J, Thompson MA, Kim K, Callander N. Angiogenic Blockade with Bevacizumab Does Not Increase Response to Lenalidomide and Low Dose Dexamethasone in Relapsed or Refractory Myeloma Blood. 120: 5041-5041. DOI: 10.1182/Blood.V120.21.5041.5041  0.602
2012 Hope C, Hebron E, Kim J, Jensen J, Flanagan C, Bhatia N, Leith C, Maroulakou I, Mitsiades CS, Miyamoto S, Callander N, Hematti P, Asimakopoulos F. Molecular Pathways That Determine the Activation State of Macrophages within the Myeloma Niche Blood. 120: 443-443. DOI: 10.1182/Blood.V120.21.443.443  0.447
2012 Chorom P, Young EW, Callander N, Beebe DJ, Miyamoto S. Microfluidic Platform Enabling Primary Multiple Myeloma Mono- and Cis-Co-Culture Analysis Blood. 120: 1830-1830. DOI: 10.1182/Blood.V120.21.1830.1830  0.324
2012 Young E, Pak C, Miyamoto S, Beebe D. Abstract 3197: Functional microscale cell-based systems for studying hematologic cancers in complex microenvironments Cancer Research. 72: 3197-3197. DOI: 10.1158/1538-7445.Am2012-3197  0.498
2011 Mishra S, Gray CB, Miyamoto S, Bers DM, Brown JH. Location matters: clarifying the concept of nuclear and cytosolic CaMKII subtypes. Circulation Research. 109: 1354-62. PMID 21998325 DOI: 10.1161/Circresaha.111.248401  0.361
2011 Lee MH, Mabb AM, Gill GB, Yeh ET, Miyamoto S. NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress. Molecular Cell. 43: 180-91. PMID 21777808 DOI: 10.1016/J.Molcel.2011.06.017  0.801
2011 Yang Y, Xia F, Hermance N, Mabb A, Simonson S, Morrissey S, Gandhi P, Munson M, Miyamoto S, Kelliher MA. A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage. Molecular and Cellular Biology. 31: 2774-86. PMID 21606198 DOI: 10.1128/Mcb.01139-10  0.792
2011 Wu L, Shao L, An N, Wang J, Pazhanisamy S, Feng W, Hauer-Jensen M, Miyamoto S, Zhou D. IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. Plos One. 6: e18447. PMID 21490922 DOI: 10.1371/Journal.Pone.0018447  0.443
2011 Wuerzberger-Davis SM, Chen Y, Yang DT, Kearns JD, Bates PW, Lynch C, Ladell NC, Yu M, Podd A, Zeng H, Huang TT, Wen R, Hoffmann A, Wang D, Miyamoto S. Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation. Immunity. 34: 188-200. PMID 21333553 DOI: 10.1016/J.Immuni.2011.01.014  0.774
2011 Miyamoto S. Nuclear initiated NF-κB signaling: NEMO and ATM take center stage. Cell Research. 21: 116-30. PMID 21187855 DOI: 10.1038/Cr.2010.179  0.543
2011 Mehraein-Ghomi F, Basu HS, Miyamoto S, Wilding G. Abstract 2165: Identification of a novel pathway of castrate resistant prostate cancer (CRPCa) growth Cancer Research. 71: 2165-2165. DOI: 10.1158/1538-7445.Am2011-2165  0.526
2010 Wu ZH, Wong ET, Shi Y, Niu J, Chen Z, Miyamoto S, Tergaonkar V. ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress. Molecular Cell. 40: 75-86. PMID 20932476 DOI: 10.1016/J.Molcel.2010.09.010  0.518
2010 Zhang D, Contu R, Latronico MV, Zhang J, Zhang JL, Rizzi R, Catalucci D, Miyamoto S, Huang K, Ceci M, Gu Y, Dalton ND, Peterson KL, Guan KL, Brown JH, et al. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. The Journal of Clinical Investigation. 120: 2805-16. PMID 20644257 DOI: 10.1172/Jci43008  0.354
2010 Markovina S, Callander NS, O'Connor SL, Xu G, Shi Y, Leith CP, Kim K, Trivedi P, Kim J, Hematti P, Miyamoto S. Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-kappaB activity in myeloma cells. Molecular Cancer. 9: 176. PMID 20604947 DOI: 10.1186/1476-4598-9-176  0.789
2010 Miyamoto S, Purcell NH, Smith JM, Gao T, Whittaker R, Huang K, Castillo R, Glembotski CC, Sussman MA, Newton AC, Brown JH. PHLPP-1 negatively regulates Akt activity and survival in the heart. Circulation Research. 107: 476-84. PMID 20576936 DOI: 10.1161/Circresaha.109.215020  0.363
2010 Miyamoto S, Del Re DP, Xiang SY, Zhao X, Florholmen G, Brown JH. Revisited and revised: is RhoA always a villain in cardiac pathophysiology? Journal of Cardiovascular Translational Research. 3: 330-43. PMID 20559774 DOI: 10.1007/S12265-010-9192-8  0.393
2010 Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, ... ... Miyamoto S, et al. Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circulation Research. 106: 1265-74. PMID 20203306 DOI: 10.1161/Circresaha.109.212035  0.337
2010 Wuerzberger-Davis SM, Miyamoto S. TAK-ling IKK activation: "Ub" the judge. Science Signaling. 3: pe3. PMID 20086238 DOI: 10.1126/Scisignal.3105Pe3  0.802
2009 McCool K, Miyamoto S. A PAR-SUMOnious mechanism of NEMO activation. Molecular Cell. 36: 349-50. PMID 19917242 DOI: 10.1016/J.Molcel.2009.10.022  0.804
2009 Miyamoto S, Murphy AN, Brown JH. Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue. Journal of Bioenergetics and Biomembranes. 41: 169-80. PMID 19377835 DOI: 10.1007/S10863-009-9205-Y  0.365
2009 Miyamoto S, Rubio M, Sussman MA. Nuclear and mitochondrial signalling Akts in cardiomyocytes. Cardiovascular Research. 82: 272-85. PMID 19279164 DOI: 10.1093/Cvr/Cvp087  0.417
2009 Rubio M, Avitabile D, Fischer K, Emmanuel G, Gude N, Miyamoto S, Mishra S, Schaefer EM, Brown JH, Sussman MA. Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes. Journal of Molecular and Cellular Cardiology. 47: 96-103. PMID 19269295 DOI: 10.1016/J.Yjmcc.2009.02.022  0.44
2009 Callander NS, Markovina S, Juckett MB, Wagner E, Kolesar J, Longo W, Williams EC, Kim K, Werndli J, Miyamoto S. The Addition of Bevacizumab (B) to Lenalidomide and Low Dose Dexamethasone Does Not Significantly Increase Response in Relapsed or Refractory Multiple Myeloma (NCI#7317). Blood. 114: 3885-3885. DOI: 10.1182/Blood.V114.22.3885.3885  0.643
2008 Del Re DP, Miyamoto S, Brown JH. Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection. The Journal of Biological Chemistry. 283: 35622-9. PMID 18854312 DOI: 10.1074/Jbc.M804036200  0.441
2008 Markovina S, Callander NS, O'Connor SL, Kim J, Werndli JE, Raschko M, Leith CP, Kahl BS, Kim K, Miyamoto S. Bortezomib-resistant nuclear factor-kappaB activity in multiple myeloma cells. Molecular Cancer Research : McR. 6: 1356-64. PMID 18708367 DOI: 10.1158/1541-7786.Mcr-08-0108  0.829
2008 Wu ZH, Miyamoto S. Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress. The Embo Journal. 27: 1963-73. PMID 18583959 DOI: 10.1038/Emboj.2008.127  0.57
2008 Ni CY, Wu ZH, Florence WC, Parekh VV, Arrate MP, Pierce S, Schweitzer B, Van Kaer L, Joyce S, Miyamoto S, Ballard DW, Oltz EM. Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 180: 7107-11. PMID 18490708 DOI: 10.4049/Jimmunol.180.11.7107  0.524
2008 Yang DT, Young KH, Kahl BS, Markovina S, Miyamoto S. Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma. Molecular Cancer. 7: 40. PMID 18489772 DOI: 10.1186/1476-4598-7-40  0.769
2008 Yang DT, Wuerzberger-Davis S, Chen Y, Yu M, Zeng H, Bates P, Wen R, Wang D, Miyamoto S. The Critical Role of Iκbα Dependent Nuclear Export of NF-κb in B-Cell Development. Blood. 112: 1533-1533. DOI: 10.1182/Blood.V112.11.1533.1533  0.785
2007 Simonson SJ, Wu ZH, Miyamoto S. CYLD: a DUB with many talents. Developmental Cell. 13: 601-3. PMID 17981127 DOI: 10.1016/J.Devcel.2007.10.009  0.451
2007 Wu ZH, Miyamoto S. Many faces of NF-kappaB signaling induced by genotoxic stress. Journal of Molecular Medicine (Berlin, Germany). 85: 1187-202. PMID 17607554 DOI: 10.1007/S00109-007-0227-9  0.575
2007 Mabb AM, Miyamoto S. SUMO and NF-kappaB ties. Cellular and Molecular Life Sciences : Cmls. 64: 1979-96. PMID 17530464 DOI: 10.1007/S00018-007-7005-2  0.77
2007 Del Re DP, Miyamoto S, Brown JH. RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis. The Journal of Biological Chemistry. 282: 8069-78. PMID 17234627 DOI: 10.1074/Jbc.M604298200  0.425
2007 Berchtold CM, Wu ZH, Huang TT, Miyamoto S. Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli. Molecular and Cellular Biology. 27: 497-509. PMID 17074802 DOI: 10.1128/Mcb.01772-06  0.55
2007 Wuerzberger-Davis SM, Nakamura Y, Seufzer BJ, Miyamoto S. NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage. Oncogene. 26: 641-51. PMID 16862178 DOI: 10.1038/Sj.Onc.1209815  0.798
2007 Yang DT, Young KH, Kahl BS, Miyamoto S. Bortezomib Resistant Constitutive NF-κB Activation in Mantle Cell Lymphoma. Blood. 110: 3465-3465. DOI: 10.1182/Blood.V110.11.3465.3465  0.552
2007 Re DPD, Miyamoto S, Brown JH. RhoA signaling in cardiomyocyte survival and apoptosis Journal of Molecular and Cellular Cardiology. 42. DOI: 10.1016/J.Yjmcc.2007.03.754  0.324
2006 Mabb AM, Wuerzberger-Davis SM, Miyamoto S. PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress. Nature Cell Biology. 8: 986-93. PMID 16906147 DOI: 10.1038/Ncb1458  0.826
2006 Chang PY, Draheim K, Kelliher MA, Miyamoto S. NFKB1 is a direct target of the TAL1 oncoprotein in human T leukemia cells. Cancer Research. 66: 6008-13. PMID 16778171 DOI: 10.1158/0008-5472.Can-06-0194  0.804
2006 Chang PY, Miyamoto S. Nuclear factor-kappaB dimer exchange promotes a p21(waf1/cip1) superinduction response in human T leukemic cells. Molecular Cancer Research : McR. 4: 101-12. PMID 16513841 DOI: 10.1158/1541-7786.Mcr-05-0259  0.842
2006 Wu ZH, Shi Y, Tibbetts RS, Miyamoto S. Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli. Science (New York, N.Y.). 311: 1141-6. PMID 16497931 DOI: 10.1126/Science.1121513  0.551
2006 Howes AL, Miyamoto S, Adams JW, Woodcock EA, Brown JH. Galphaq expression activates EGFR and induces Akt mediated cardiomyocyte survival: dissociation from Galphaq mediated hypertrophy. Journal of Molecular and Cellular Cardiology. 40: 597-604. PMID 16466740 DOI: 10.1016/J.Yjmcc.2005.12.003  0.401
2006 Callander NS, Miyamoto S, Kahl B, Markovina S, Raschko M, Werndl J, Leith C, McCoy A. Phase II Trial of Bortezomib Combined with Weekly Doxorubicin and Oral Dexamethasone for Relapsed or Refractory Multiple Myeloma (MM): Effect of NF-κB Activation on Response. Blood. 108: 3545-3545. DOI: 10.1182/Blood.V108.11.3545.3545  0.73
2005 Wu ZH, Mabb A, Miyamoto S. PIDD: a switch hitter. Cell. 123: 980-2. PMID 16360026 DOI: 10.1016/J.Cell.2005.11.025  0.765
2005 Berchtold CM, Chen KS, Miyamoto S, Gould MN. Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway. Cancer Research. 65: 8558-66. PMID 16166337 DOI: 10.1158/0008-5472.Can-04-4072  0.47
2005 Wuerzberger-Davis SM, Chang PY, Berchtold C, Miyamoto S. Enhanced G2-M arrest by nuclear factor-{kappa}B-dependent p21waf1/cip1 induction. Molecular Cancer Research : McR. 3: 345-53. PMID 15972853 DOI: 10.1158/1541-7786.Mcr-05-0028  0.831
2005 O'Connor S, Markovina S, Miyamoto S. Evidence for a phosphorylation-independent role for Ser 32 and 36 in proteasome inhibitor-resistant (PIR) IkappaBalpha degradation in B cells. Experimental Cell Research. 307: 15-25. PMID 15922723 DOI: 10.1016/J.Yexcr.2005.02.015  0.803
2005 O'Connor S, Shumway S, Miyamoto S. Inhibition of IkappaBalpha nuclear export as an approach to abrogate nuclear factor-kappaB-dependent cancer cell survival. Molecular Cancer Research : McR. 3: 42-9. PMID 15671248  0.846
2004 Bates PW, Miyamoto S. Expanded nuclear roles for IkappaBs. Science's Stke : Signal Transduction Knowledge Environment. 2004: pe48. PMID 15479861 DOI: 10.1126/Stke.2542004Pe48  0.539
2004 O'Connor S, Shumway SD, Amanna IJ, Hayes CE, Miyamoto S. Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells. Molecular and Cellular Biology. 24: 4895-908. PMID 15143182 DOI: 10.1128/Mcb.24.11.4895-4908.2004  0.832
2004 Miyamoto S. RelA life and death decisions. Molecular Cell. 13: 763-4. PMID 15053867 DOI: 10.1016/S1097-2765(04)00158-3  0.371
2004 Shumway SD, Miyamoto S. A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells. The Biochemical Journal. 380: 173-80. PMID 14763901 DOI: 10.1042/Bj20031796  0.815
2004 Zhang T, Miyamoto S, Brown JH. Cardiomyocyte calcium and calcium/calmodulin-dependent protein kinase II: friends or foes? Recent Progress in Hormone Research. 59: 141-68. PMID 14749501 DOI: 10.1210/Rp.59.1.141  0.306
2003 Huang TT, Wuerzberger-Davis SM, Wu ZH, Miyamoto S. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell. 115: 565-76. PMID 14651848 DOI: 10.1016/S0092-8674(03)00895-X  0.815
2003 Criswell T, Leskov K, Miyamoto S, Luo G, Boothman DA. Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation. Oncogene. 22: 5813-27. PMID 12947388 DOI: 10.1038/Sj.Onc.1206680  0.405
2003 Howes AL, Arthur JF, Zhang T, Miyamoto S, Adams JW, Dorn GW, Woodcock EA, Brown JH. Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. The Journal of Biological Chemistry. 278: 40343-51. PMID 12900409 DOI: 10.1074/Jbc.M305964200  0.414
2003 Narayanan K, Krishnamoorthy B, Ezhilarasan R, Miyamoto S, Balakrishnan A. Targeting apoptotic signalling pathway and pro-inflammatory cytokine expression as therapeutic intervention in TPE induced lung damage. Cell Biology International. 27: 375-82. PMID 12788054 DOI: 10.1016/S1065-6995(03)00014-3  0.401
2003 Kawamura S, Miyamoto S, Brown JH. Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation. The Journal of Biological Chemistry. 278: 31111-7. PMID 12777392 DOI: 10.1074/Jbc.M300725200  0.421
2003 Zhang T, Maier LS, Dalton ND, Miyamoto S, Ross J, Bers DM, Brown JH. The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circulation Research. 92: 912-9. PMID 12676814 DOI: 10.1161/01.Res.0000069686.31472.C5  0.31
2002 Huang TT, Feinberg SL, Suryanarayanan S, Miyamoto S. The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors. Molecular and Cellular Biology. 22: 5813-25. PMID 12138192 DOI: 10.1128/Mcb.22.16.5813-5825.2002  0.449
2002 Narayanan K, Seufzer BJ, Brockman-Schneider RA, Gern JE, Balakrishnan A, Miyamoto S. CD14-dependent activation of NF-kappaB by filarial parasitic sheath proteins. Cell Biology International. 26: 43-54. PMID 11779220 DOI: 10.1006/Cbir.2001.0828  0.508
2002 Shumway SD, Berchtold CM, Gould MN, Miyamoto S. Evidence for unique calmodulin-dependent nuclear factor-kappaB regulation in WEHI-231 B cells. Molecular Pharmacology. 61: 177-85. PMID 11752219 DOI: 10.1124/Mol.61.1.177  0.829
2001 Huang TT, Miyamoto S. Postrepression activation of NF-κB requires the amino-terminal nuclear export signal specific to IκBα Molecular and Cellular Biology. 21: 4737-4747. PMID 11416149 DOI: 10.1128/Mcb.21.14.4737-4747.2001  0.557
2000 Miyamoto S, Huang TT, Wuerzberger-Davis S, Bornmann WG, Pink JJ, Tagliarino C, Kinsella TJ, Boothman DA. Cellular and molecular responses to topoisomerase I poisons: Exploiting synergy for improved radiotherapy Annals of the New York Academy of Sciences. 922: 274-292. PMID 11193903 DOI: 10.1111/J.1749-6632.2000.Tb07045.X  0.8
2000 Krishnamoorthy B, Narayanan K, Miyamoto S, Balakrishnan A. Epithelial cells release proinflammatory cytokines and undergo c-Myc-induced apoptosis on exposure to filarial parasitic sheath protein-Bcl2 mediates rescue by activating c-H-Ras. In Vitro Cellular & Developmental Biology. Animal. 36: 532-8. PMID 11149753 DOI: 10.1290/1071-2690(2000)036<0532:Ecrpca>2.0.Co;2  0.38
2000 Narayanan K, Balakrishnan A, Miyamoto S. NF-κB is essential for induction of pro-inflammatory cytokine genes by filarial parasitic sheath proteins Molecular Immunology. 37: 115-123. PMID 10865110 DOI: 10.1016/S0161-5890(00)00039-0  0.562
2000 Fields ER, Seufzer BJ, Oltz EM, Miyamoto S. A switch in distinct I kappa B alpha degradation mechanisms mediates constitutive NF-kappa B activation in mature B cells. Journal of Immunology (Baltimore, Md. : 1950). 164: 4762-7. PMID 10779782 DOI: 10.4049/Jimmunol.164.9.4762  0.435
2000 Huang TT, Wuerzberger-Davis SM, Seufzer BJ, Shumway SD, Kurama T, Boothman DA, Miyamoto S. NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events. The Journal of Biological Chemistry. 275: 9501-9. PMID 10734098 DOI: 10.1074/Jbc.275.13.9501  0.848
2000 Yang CR, Wilson-Van Patten C, Planchon SM, Wuerzberger-Davis SM, Davis TW, Cuthill S, Miyamoto S, Boothman DA. Coordinate modulation of Sp1, NF-kappa B, and p53 in confluent human malignant melanoma cells after ionizing radiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 379-90. PMID 10657994 DOI: 10.1096/Fasebj.14.2.379  0.776
2000 Huang TT, Kudo N, Yoshida M, Miyamoto S. A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes. Proceedings of the National Academy of Sciences of the United States of America. 97: 1014-9. PMID 10655476 DOI: 10.1073/Pnas.97.3.1014  0.524
2000 Zhang Y, Sun X, Muraoka K, Ikeda A, Miyamoto S, Shimizu H, Yoshioka K, Yamamoto K. Immunosuppressant FK506 activates NF-kappaB through the proteasome-mediated degradation of IkappaBalpha. Requirement for Ikappabalpha n-terminal phosphorylation but not ubiquitination sites. The Journal of Biological Chemistry. 274: 34657-62. PMID 10574930 DOI: 10.1074/Jbc.274.49.34657  0.418
1999 Shumway SD, Maki M, Miyamoto S. The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain. The Journal of Biological Chemistry. 274: 30874-81. PMID 10521480 DOI: 10.1074/Jbc.274.43.30874  0.73
1999 Satomi Y, Miyamoto S, Gould MN. Induction of AP-1 activity by perillyl alcohol in breast cancer cells. Carcinogenesis. 20: 1957-1961. PMID 10506111 DOI: 10.1093/Carcin/20.10.1957  0.417
1998 Miyamoto S, Seufzer BJ, Shumway SD. Novel IkappaB alpha proteolytic pathway in WEHI231 immature B cells. Molecular and Cellular Biology. 18: 19-29. PMID 9418849 DOI: 10.1128/Mcb.18.1.19  0.767
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