| Year |
Citation |
Score |
| 2021 |
Kang JW, Zhan Z, Ji G, Sang Y, Zhou D, Li Y, Feng H, Cheng T. PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells. Signal Transduction and Targeted Therapy. 6: 129. PMID 33785736 DOI: 10.1038/s41392-021-00510-w |
0.328 |
|
| 2020 |
Faust HJ, Zhang H, Han J, Wolf MT, Jeon OH, Sadtler K, Peña AN, Chung L, Maestas DR, Tam AJ, Pardoll DM, Campisi J, Housseau F, Zhou D, Bingham CO, et al. IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis. The Journal of Clinical Investigation. PMID 32955487 DOI: 10.1172/Jci134091 |
0.363 |
|
| 2020 |
Kim HN, Xiong J, MacLeod RS, Iyer S, Fujiwara Y, Cawley KM, Han L, He Y, Thostenson JD, Ferreira E, Jilka RL, Zhou D, Almeida M, O'Brien CA. Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence. Jci Insight. PMID 32870816 DOI: 10.1172/Jci.Insight.138815 |
0.307 |
|
| 2020 |
Acklin S, Zhang M, Du W, Zhao X, Plotkin M, Chang J, Campisi J, Zhou D, Xia F. Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice. Scientific Reports. 10: 14170. PMID 32843706 DOI: 10.1038/S41598-020-71042-6 |
0.431 |
|
| 2020 |
Vara N, Liu Y, Yan Y, Lensing SY, Colorado N, Robinson D, Zhang J, Zhang X, Peterson EA, Baltz NJ, Zhou D, Bertaina A, Johann DJ, Emanuel PD, Liu YL. Sustained fetal hematopoiesis causes juvenile death from leukemia: evidence from a dual-age-specific mouse model. Blood Advances. 4: 3728-3740. PMID 32777070 DOI: 10.1182/Bloodadvances.2020002326 |
0.338 |
|
| 2020 |
He Y, Khan S, Huo Z, Lv D, Zhang X, Liu X, Yuan Y, Hromas R, Xu M, Zheng G, Zhou D. Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies. Journal of Hematology & Oncology. 13: 103. PMID 32718354 DOI: 10.1186/S13045-020-00924-Z |
0.319 |
|
| 2020 |
He Y, Koch R, Budamagunta V, Zhang P, Zhang X, Khan S, Thummuri D, Ortiz YT, Zhang X, Lv D, Wiegand JS, Li W, Palmer AC, Zheng G, Weinstock DM, ... Zhou D, et al. DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas. Journal of Hematology & Oncology. 13: 95. PMID 32677976 DOI: 10.1186/S13045-020-00928-9 |
0.372 |
|
| 2020 |
Zhang X, He Y, Zhang P, Budamagunta V, Lv D, Thummuri D, Yang Y, Pei J, Yuan Y, Zhou D, Zheng G. Discovery of IAP-recruiting BCL-X PROTACs as potent degraders across multiple cancer cell lines. European Journal of Medicinal Chemistry. 199: 112397. PMID 32388279 DOI: 10.1016/J.Ejmech.2020.112397 |
0.34 |
|
| 2020 |
He Y, Zhang X, Chang J, Kim HN, Zhang P, Wang Y, Khan S, Liu X, Zhang X, Lv D, Song L, Li W, Thummuri D, Yuan Y, Wiegand JS, ... ... Zhou D, et al. Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity. Nature Communications. 11: 1996. PMID 32332723 DOI: 10.1038/S41467-020-15838-0 |
0.369 |
|
| 2020 |
Zhang X, Thummuri D, Liu X, Hu W, Zhang P, Khan S, Yuan Y, Zhou D, Zheng G. Discovery of PROTAC BCL-X degraders as potent anticancer agents with low on-target platelet toxicity. European Journal of Medicinal Chemistry. 192: 112186. PMID 32145645 DOI: 10.1016/J.Ejmech.2020.112186 |
0.332 |
|
| 2020 |
He Y, Li W, Lv D, Zhang X, Zhang X, Ortiz YT, Budamagunta V, Campisi J, Zheng G, Zhou D. Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity. Aging Cell. e13117. PMID 32064756 DOI: 10.1111/Acel.13117 |
0.456 |
|
| 2019 |
Khan S, Zhang X, Lv D, Zhang Q, He Y, Zhang P, Liu X, Thummuri D, Yuan Y, Wiegand JS, Pei J, Zhang W, Sharma A, McCurdy CR, Kuruvilla VM, ... ... Zhou D, et al. A selective BCL-X PROTAC degrader achieves safe and potent antitumor activity. Nature Medicine. PMID 31792461 DOI: 10.1038/S41591-019-0668-Z |
0.328 |
|
| 2019 |
Zhang X, Thummuri D, He Y, Liu X, Zhang P, Zhou D, Zheng G. Utilizing PROTAC technology to address the on-target platelet toxicity associated with inhibition of BCL-X. Chemical Communications (Cambridge, England). PMID 31754664 DOI: 10.1039/C9Cc07217A |
0.375 |
|
| 2019 |
Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O, Bishop C, Campisi J, Collado M, Evangelou K, Ferbeyre G, Gil J, Hara E, Krizhanovsky V, Jurk D, Maier AB, ... ... Zhou D, et al. Cellular Senescence: Defining a Path Forward. Cell. 179: 813-827. PMID 31675495 DOI: 10.1016/J.Cell.2019.10.005 |
0.335 |
|
| 2019 |
Zhang C, Fondufe-Mittendorf YN, Wang C, Chen J, Cheng Q, Zhou D, Zheng Y, Geiger H, Liang Y. Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance. Haematologica. PMID 31171637 DOI: 10.3324/Haematol.2018.207092 |
0.363 |
|
| 2019 |
He Y, Thummuri D, Zheng G, Okunieff P, Citrin DE, Vujaskovic Z, Zhou D. Cellular senescence and radiation-induced pulmonary fibrosis. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 30981698 DOI: 10.1016/J.Trsl.2019.03.006 |
0.356 |
|
| 2019 |
Xu F, Fang Y, Yan L, Xu L, Zhang S, Cao Y, Xu L, Zhang X, Xie J, Jiang G, Ge C, An N, Zhou D, Yuan N, Wang J. Author Correction: Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy. Scientific Reports. 9: 5594. PMID 30944356 DOI: 10.1038/S41598-019-41388-7 |
0.316 |
|
| 2019 |
Patil P, Dong Q, Wang D, Chang J, Wiley C, Demaria M, Lee J, Kang J, Niedernhofer LJ, Robbins PD, Sowa G, Campisi J, Zhou D, Vo N. Systemic clearance of p16 -positive senescent cells mitigates age-associated intervertebral disc degeneration. Aging Cell. e12927. PMID 30900385 DOI: 10.1111/Acel.12927 |
0.312 |
|
| 2019 |
Kim HN, Chang J, Iyer S, Han L, Campisi J, Manolagas SC, Zhou D, Almeida M. Elimination of senescent osteoclast progenitors has no effect on the age-associated loss of bone mass in mice. Aging Cell. e12923. PMID 30773784 DOI: 10.1111/Acel.12923 |
0.415 |
|
| 2019 |
Cho JJ, Xu Z, Parthasarathy U, Drashansky TT, Helm EY, Zuniga AN, Lorentsen KJ, Mansouri S, Cho JY, Edelmann MJ, Duong DM, Gehring T, Seeholzer T, Krappmann D, Uddin MN, ... ... Zhou D, et al. Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation. Nature Communications. 10: 701. PMID 30741923 DOI: 10.1038/S41467-019-08605-3 |
0.336 |
|
| 2019 |
He Y, Koch R, Budamagunta V, Lv D, Khan S, Zhang X, Wiegand JS, Zheng G, Weinstock DM, Zhou D. DT2216, a BCL-XL Proteolysis Targeting Chimera (PROTAC), Is a Potent Anti T-Cell Lymphoma Agent That Does Not Induce Significant Thrombocytopenia Blood. 134: 303-303. DOI: 10.1182/Blood-2019-125820 |
0.346 |
|
| 2019 |
He Y, Chang J, Lv D, Kim H, Almeida M, Zhang X, Mao X, Zhao X, Li L, Campisi J, Liang Y, Zhou D. Long-Term Clearance of Senescent Cells Prevents the Hematopoietic Stem Cell Aging in Naturally Aged Mice Blood. 134: 1204-1204. DOI: 10.1182/Blood-2019-123159 |
0.384 |
|
| 2018 |
Liu X, Wang Y, Zhang X, Gao Z, Zhang S, Shi P, Zhang X, Song L, Hendrickson H, Zhou D, Zheng G. Senolytic activity of piperlongumine analogues: Synthesis and biological evaluation. Bioorganic & Medicinal Chemistry. PMID 29925484 DOI: 10.1016/J.Bmc.2018.06.013 |
0.363 |
|
| 2018 |
Shao L, Chang J, Feng W, Wang X, Williamson EA, Li Y, Schajnovitz A, Scadden D, Mortensen LJ, Lin CP, Li L, Paulson A, Downing J, Zhou D, Hromas RA. The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow. Nature Communications. 9: 2377. PMID 29915352 DOI: 10.1038/S41467-018-04716-5 |
0.305 |
|
| 2018 |
Zhang X, Zhang S, Liu X, Wang Y, Chang J, Zhang X, Mackintosh SG, Tackett AJ, He Y, Lv D, Laberge RM, Campisi J, Wang J, Zheng G, Zhou D. Oxidation resistance 1 is a novel senolytic target. Aging Cell. e12780. PMID 29766639 DOI: 10.1111/Acel.12780 |
0.371 |
|
| 2018 |
Li C, Luo Y, Shao L, Meng A, Zhou D. NOS2 deficiency has no influence on the radiosensitivity of the hematopoietic system. Cell & Bioscience. 8: 33. PMID 29736233 DOI: 10.1186/S13578-018-0228-0 |
0.395 |
|
| 2018 |
Luo Y, Shao L, Chang J, Feng W, Liu YL, Cottler-Fox MH, Emanuel PD, Hauer-Jensen M, Bernstein ID, Liu L, Chen X, Zhou J, Murray PJ, Zhou D. M1 and M2 macrophages differentially regulate hematopoietic stem cell self-renewal and ex vivo expansion. Blood Advances. 2: 859-870. PMID 29666049 DOI: 10.1182/Bloodadvances.2018015685 |
0.322 |
|
| 2018 |
Khan S, Zhang X, Lv D, He Y, Zhang P, Liu X, Thummuri D, Zhang Q, Konopleva MY, Hromas RA, Zheng G, Zhou D. DT2216, a Synthetic Proteolytic Selectively Targeting Bcl-XL for Ubiquitination and Degradation in Tumor Cells but Not in Platelets, Is a Safer and More Potent Antitumor Agent Than Navitoclax Blood. 132: 2698-2698. DOI: 10.1182/Blood-2018-99-114762 |
0.419 |
|
| 2017 |
Wang Y, Chang J, Li X, Pathak R, Sridharan V, Jones T, Mao XW, Nelson G, Boerma M, Hauer-Jensen M, Zhou D, Shao L. Low doses of oxygen ion irradiation cause long-term damage to bone marrow hematopoietic progenitor and stem cells in mice. Plos One. 12: e0189466. PMID 29232383 DOI: 10.1371/Journal.Pone.0189466 |
0.378 |
|
| 2017 |
MacNicol MC, Cragle CE, McDaniel FK, Hardy LL, Wang Y, Arumugam K, Rahmatallah Y, Glazko GV, Wilczynska A, Childs GV, Zhou D, MacNicol AM. Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2. Scientific Reports. 7: 11503. PMID 28912529 DOI: 10.1038/S41598-017-11917-3 |
0.368 |
|
| 2017 |
Chang J, Wang Y, Pathak R, Sridharan V, Jones T, Mao XW, Nelson G, Boerma M, Hauer-Jensen M, Zhou D, Shao L. Whole body proton irradiation causes acute damage to bone marrow hematopoietic progenitor and stem cells in mice. International Journal of Radiation Biology. 1-9. PMID 28782442 DOI: 10.1080/09553002.2017.1356941 |
0.386 |
|
| 2017 |
Miousse IR, Chang J, Shao L, Pathak R, Nzabarushimana É, Kutanzi KR, Landes RD, Tackett AJ, Hauer-Jensen M, Zhou D, Koturbash I. Inter-Strain Differences in LINE-1 DNA Methylation in the Mouse Hematopoietic System in Response to Exposure to Ionizing Radiation. International Journal of Molecular Sciences. 18. PMID 28677663 DOI: 10.3390/Ijms18071430 |
0.363 |
|
| 2017 |
Chang J, Feng W, Wang Y, Allen AR, Turner J, Stewart B, Raber J, Hauer-Jensen M, Zhou D, Shao L. (28)Si total body irradiation injures bone marrow hematopoietic stem cells via induction of cellular apoptosis. Life Sciences in Space Research. 13: 39-44. PMID 28554508 DOI: 10.1016/J.Lssr.2017.03.003 |
0.377 |
|
| 2017 |
Pan J, Li D, Xu Y, Zhang J, Wang Y, Chen M, Lin S, Huang L, Chung EJ, Citrin DE, Wang Y, Hauer-Jensen M, Zhou D, Meng A. Inhibition of Bcl-2/xl With ABT-263 Selectively Kills Senescent Type II Pneumocytes and Reverses Persistent Pulmonary Fibrosis Induced by Ionizing Radiation in Mice. International Journal of Radiation Oncology, Biology, Physics. PMID 28479002 DOI: 10.1016/J.Ijrobp.2017.02.216 |
0.367 |
|
| 2017 |
Kim HN, Chang J, Shao L, Han L, Iyer S, Manolagas SC, O'Brien CA, Jilka RL, Zhou D, Almeida M. DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age. Aging Cell. PMID 28401730 DOI: 10.1111/Acel.12597 |
0.39 |
|
| 2017 |
Xu F, Fang Y, Yan L, Xu L, Zhang S, Cao Y, Xu L, Zhang X, Xie J, Jiang G, Ge C, An N, Zhou D, Yuan N, Wang J. Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy. Scientific Reports. 7: 45385. PMID 28345663 DOI: 10.1038/Srep45385 |
0.413 |
|
| 2017 |
Liu Y, Zhang C, Li Z, Wang C, Jia J, Gao T, Hildebrandt G, Zhou D, Bondada S, Ji P, St Clair D, Liu J, Zhan C, Geiger H, Wang S, et al. Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice. Stem Cell Reports. PMID 28330618 DOI: 10.1016/J.Stemcr.2017.02.009 |
0.403 |
|
| 2017 |
Xu F, Li X, Yan L, Yuan N, Fang Y, Cao Y, Xu L, Zhang X, Xu L, Ge C, An N, Jiang G, Xie J, Zhang H, Jiang J, ... ... Zhou D, et al. Autophagy Promotes the Repair of Radiation-Induced DNA Damage in Bone Marrow Hematopoietic Cells via Enhanced STAT3 Signaling. Radiation Research. 187: 382-396. PMID 28327001 DOI: 10.1667/Rr14640.1 |
0.458 |
|
| 2017 |
Aylin-Burns N, Krager KJ, Zhou D, Hauer-Jensen M. Investigating the effects of hyperbaric oxygen on mitochondrial function of endothelial progenitor cells. The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.711.7 |
0.307 |
|
| 2016 |
Demaria M, O'Leary MN, Chang J, Shao L, Liu S, Alimirah F, Koenig K, Le C, Mitin N, Deal AM, Alston S, Academia EC, Kilmarx S, Valdovinos A, Wang B, ... ... Zhou D, et al. Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse. Cancer Discovery. PMID 27979832 DOI: 10.1158/2159-8290.Cd-16-0241 |
0.447 |
|
| 2016 |
Pathak R, Ghosh SP, Zhou D, Hauer-Jensen M. The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM). International Journal of Molecular Sciences. 17. PMID 27869747 DOI: 10.3390/Ijms17111937 |
0.335 |
|
| 2016 |
Wang Y, Boerma M, Zhou D. Ionizing Radiation-Induced Endothelial Cell Senescence and Cardiovascular Diseases. Radiation Research. PMID 27387862 DOI: 10.1667/Rr14445.1 |
0.402 |
|
| 2016 |
Chang J, Luo Y, Wang Y, Pathak R, Sridharan V, Jones T, Mao XW, Nelson G, Boerma M, Hauer-Jensen M, Zhou D, Shao L. Low Doses of Oxygen Ion Irradiation Cause Acute Damage to Hematopoietic Cells in Mice. Plos One. 11: e0158097. PMID 27367604 DOI: 10.1371/Journal.Pone.0158097 |
0.41 |
|
| 2016 |
Wang Y, Chang J, Shao L, Feng W, Luo Y, Chow M, Du W, Meng A, Zhou D. Hematopoietic Stem Cells from Ts65Dn Mice Are Deficient in the Repair of DNA Double-Strand Breaks. Radiation Research. PMID 27243896 DOI: 10.1667/Rr14407.1 |
0.396 |
|
| 2016 |
Liu YL, Yan Y, Webster C, Shao L, Lensing SY, Ni H, Feng W, Colorado N, Pathak R, Xiang Z, Hauer-Jensen M, Li S, Zhou D, Emanuel PD. Timing of the loss of PTEN protein determines disease severity in a mouse model of myeloid malignancy. Blood. PMID 26764354 DOI: 10.1182/Blood-2015-05-646216 |
0.352 |
|
| 2016 |
Ma X, Li X, Peng D, Wang H, Li L, Zhou H, Zhou D, Luo Y, Liu L. Inhibition of Both Activated p38 Mapkα and mTORC1 Potentiates the Effect of SR1 on Promoting Hematopoietic Reconstitution of Ex Vivo Expanded Human Umbilical Cord Blood Hematopoietic Stem Cells Blood. 128: 2173-2173. DOI: 10.1182/Blood.V128.22.2173.2173 |
0.432 |
|
| 2015 |
Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, et al. EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair. Plos Genetics. 11: e1005675. PMID 26684013 DOI: 10.1371/Journal.Pgen.1005675 |
0.32 |
|
| 2015 |
Chang J, Wang Y, Shao L, Laberge RM, Demaria M, Campisi J, Janakiraman K, Sharpless NE, Ding S, Feng W, Luo Y, Wang X, Aykin-Burns N, Krager K, Ponnappan U, ... ... Zhou D, et al. Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. Nature Medicine. PMID 26657143 DOI: 10.1038/Nm.4010 |
0.406 |
|
| 2015 |
Wilke C, Holtan SG, Sharkey L, DeFor T, Arora M, Premakanthan P, Yohe S, Vagge S, Zhou D, Holter Chakrabarty JL, Mahe M, Corvo R, Dusenbery K, Storme G, Weisdorf DJ, et al. Marrow damage and hematopoietic recovery following allogeneic bone marrow transplantation for acute leukemias: Effect of radiation dose and conditioning regimen. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 26653357 DOI: 10.1016/J.Radonc.2015.11.012 |
0.402 |
|
| 2015 |
Li C, Lu L, Zhang J, Huang S, Xing Y, Zhao M, Zhou D, Li D, Meng A. Granulocyte colony-stimulating factor exacerbates hematopoietic stem cell injury after irradiation. Cell & Bioscience. 5: 65. PMID 26609358 DOI: 10.1186/s13578-015-0057-3 |
0.41 |
|
| 2015 |
Zheng J, Wang J, Pouliot M, Authier S, Zhou D, Loose DS, Hauer-Jensen M. Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses. Bmc Genomics. 16: 984. PMID 26589571 DOI: 10.1186/S12864-015-2168-Y |
0.405 |
|
| 2015 |
Wang J, Shao L, Hendrickson HP, Liu L, Chang J, Luo Y, Seng J, Pouliot M, Authier S, Zhou D, Allaben W, Hauer-Jensen M. Total Body Irradiation in the "Hematopoietic" Dose Range Induces Substantial Intestinal Injury in Non-Human Primates. Radiation Research. PMID 26495870 DOI: 10.1667/Rr14191.1 |
0.388 |
|
| 2015 |
Xu G, Wu H, Zhang J, Li D, Wang Y, Wang Y, Zhang H, Lu L, Li C, Huang S, Xing Y, Zhou D, Meng A. Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice. Free Radical Biology & Medicine. PMID 26086617 DOI: 10.1016/j.freeradbiomed.2015.05.045 |
0.358 |
|
| 2015 |
Pathak R, Shao L, Ghosh SP, Zhou D, Boerma M, Weiler H, Hauer-Jensen M. Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice. Plos One. 10: e0122511. PMID 25860286 DOI: 10.1371/Journal.Pone.0122511 |
0.389 |
|
| 2015 |
Chang J, Feng W, Wang Y, Luo Y, Allen AR, Koturbash I, Turner J, Stewart B, Raber J, Hauer-Jensen M, Zhou D, Shao L. Whole-body proton irradiation causes long-term damage to hematopoietic stem cells in mice. Radiation Research. 183: 240-8. PMID 25635345 DOI: 10.1667/Rr13887.1 |
0.409 |
|
| 2015 |
Coleman EA, Lee JY, Erickson SW, Goodwin JA, Sanathkumar N, Raj VR, Zhou D, McKelvey KD, Apewokin S, Stephens O, Enderlin CA, Vangsted AJ, Reed PJ, Anaissie EJ. GWAS of 972 autologous stem cell recipients with multiple myeloma identifies 11 genetic variants associated with chemotherapy-induced oral mucositis. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. 23: 841-9. PMID 25218607 DOI: 10.1007/S00520-014-2406-X |
0.326 |
|
| 2015 |
Li X, Ma X, Luo Y, Danyue P, Zhou D, Liu L. Inhibition of Both Activated p38 MAPK and mTOR C1 Potentiates the Effect of SR1 on Promotion of Hematopoietic Stem Cell Expansion Ex Vivo Blood. 126: 381-381. DOI: 10.1182/Blood.V126.23.381.381 |
0.409 |
|
| 2014 |
You Y, Wen R, Pathak R, Li A, Li W, St Clair D, Hauer-Jensen M, Zhou D, Liang Y. Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3 pathway. Cell Death & Disease. 5: e1493. PMID 25341047 DOI: 10.1038/Cddis.2014.443 |
0.518 |
|
| 2014 |
Pathak R, Shao L, Chafekar SM, Feng W, Ponnappan U, Fink LM, Zhou D, Hauer-Jensen M. IKKβ regulates endothelial thrombomodulin in a Klf2-dependent manner. Journal of Thrombosis and Haemostasis : Jth. 12: 1533-44. PMID 25039491 DOI: 10.1111/Jth.12664 |
0.357 |
|
| 2014 |
Zhou D, Shao L, Spitz DR. Reactive oxygen species in normal and tumor stem cells. Advances in Cancer Research. 122: 1-67. PMID 24974178 DOI: 10.1016/B978-0-12-420117-0.00001-3 |
0.388 |
|
| 2014 |
Miousse IR, Shao L, Chang J, Feng W, Wang Y, Allen AR, Turner J, Stewart B, Raber J, Zhou D, Koturbash I. Exposure to low-dose (56)Fe-ion radiation induces long-term epigenetic alterations in mouse bone marrow hematopoietic progenitor and stem cells. Radiation Research. 182: 92-101. PMID 24960414 DOI: 10.1667/Rr13580.1 |
0.403 |
|
| 2014 |
Pawar SA, Shao L, Chang J, Wang W, Pathak R, Zhu X, Wang J, Hendrickson H, Boerma M, Sterneck E, Zhou D, Hauer-Jensen M. C/EBPδ deficiency sensitizes mice to ionizing radiation-induced hematopoietic and intestinal injury. Plos One. 9: e94967. PMID 24747529 DOI: 10.1371/Journal.Pone.0094967 |
0.442 |
|
| 2014 |
Shao L, Feng W, Li H, Gardner D, Luo Y, Wang Y, Liu L, Meng A, Sharpless NE, Zhou D. Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner. Blood. 123: 3105-15. PMID 24622326 DOI: 10.1182/Blood-2013-07-515619 |
0.474 |
|
| 2014 |
Garg S, Wang W, Prabath BG, Boerma M, Wang J, Zhou D, Hauer-Jensen M. Bone marrow transplantation helps restore the intestinal mucosal barrier after total body irradiation in mice. Radiation Research. 181: 229-39. PMID 24568131 DOI: 10.1667/Rr13548.1 |
0.404 |
|
| 2014 |
Zhang J, Yang R, Zhou D, Rudolph KL, Meng A, Ju Z. Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells. Stem Cell Research. 12: 250-9. PMID 24280419 DOI: 10.1016/J.Scr.2013.11.001 |
0.397 |
|
| 2014 |
Shao L, Luo Y, Zhou D. Hematopoietic stem cell injury induced by ionizing radiation. Antioxidants & Redox Signaling. 20: 1447-62. PMID 24124731 DOI: 10.1089/Ars.2013.5635 |
0.495 |
|
| 2014 |
Luo Y, Li L, Zou P, Wang J, Shao L, Zhou D, Liu L. Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence. Transplantation. 97: 20-9. PMID 24092377 DOI: 10.1097/Tp.0B013E3182A7Fcf8 |
0.39 |
|
| 2014 |
Liu YL, Yan Y, Webster C, Shao L, Lensing SY, Ni H, Feng W, Zhou D, Xiang Z, Colorado N, Robinson D, Li S, Emanuel PD. Timing of the Loss of Pten Is Critical in Determining the Disease Phenotype in Mice- a Mouse Model for Pediatric Mixed MDS/MPN Blood. 124: 3585-3585. DOI: 10.1182/Blood.V124.21.3585.3585 |
0.366 |
|
| 2014 |
Luo Y, Shao L, Chang J, Feng W, Li C, Liu YL, Cottler-Fox M, Emanuel PD, Murray P, Zhou D. Opposite Effects of M1 and M2 Macrophages on Hematopoietic Stem Cell Self-Renewal and Ex Vivo Expansion Blood. 124: 2909-2909. DOI: 10.1182/Blood.V124.21.2909.2909 |
0.348 |
|
| 2013 |
Shao L, Wang Y, Chang J, Luo Y, Meng A, Zhou D. Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury. Translational Cancer Research. 2: 397-411. PMID 24605290 DOI: 10.3978/J.Issn.2218-676X.2013.07.03 |
0.4 |
|
| 2013 |
Li D, Wang Y, Wu H, Lu L, Wang X, Zhang J, Zhang H, Fan S, Fan F, Zhou D, Meng A. The effects of p38 MAPK inhibition combined with G-CSF administration on the hematoimmune system in mice with irradiation injury. Plos One. 8: e62921. PMID 23646161 DOI: 10.1371/Journal.Pone.0062921 |
0.398 |
|
| 2013 |
Wray J, Williamson EA, Singh SB, Wu Y, Cogle CR, Weinstock DM, Zhang Y, Lee SH, Zhou D, Shao L, Hauer-Jensen M, Pathak R, Klimek V, Nickoloff JA, Hromas R. PARP1 is required for chromosomal translocations. Blood. 121: 4359-65. PMID 23568489 DOI: 10.1182/Blood-2012-10-460527 |
0.353 |
|
| 2013 |
Wu L, Shao L, Li M, Zheng J, Wang J, Feng W, Chang J, Wang Y, Hauer-Jensen M, Zhou D. BMS-345541 sensitizes MCF-7 breast cancer cells to ionizing radiation by selective inhibition of homologous recombinational repair of DNA double-strand breaks. Radiation Research. 179: 160-70. PMID 23259762 DOI: 10.1667/Rr3034.1 |
0.461 |
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| 2013 |
Xiao Y, Wang J, Song H, Zou P, Zhou D, Liu L. CD34+ cells from patients with myelodysplastic syndrome present different p21 dependent premature senescence. Leukemia Research. 37: 333-40. PMID 23219618 DOI: 10.1016/J.Leukres.2012.11.006 |
0.419 |
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| 2013 |
Burns TA, Subathra M, Signorelli P, Choi Y, Yang X, Wang Y, Villani M, Bhalla K, Zhou D, Luberto C. Sphingomyelin synthase 1 activity is regulated by the BCR-ABL oncogene. Journal of Lipid Research. 54: 794-805. PMID 23160178 DOI: 10.1194/Jlr.M033985 |
0.422 |
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| 2013 |
Zhang H, Zhai Z, Wang Y, Zhang J, Wu H, Wang Y, Li C, Li D, Lu L, Wang X, Chang J, Hou Q, Ju Z, Zhou D, Meng A. Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice. Free Radical Biology & Medicine. 54: 40-50. PMID 23124026 DOI: 10.1016/j.freeradbiomed.2012.10.530 |
0.347 |
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| 2013 |
Coleman EA, Lee JY, Erickson S, Goodwin J, Beggs M, Sanathkumar N, Zhou D, McKelvey K, Raj V, Apewokin S, Stephens O, Enderlin C, Vangsted AJ, Reed P, Anaissie EJ. Chemotherapy-Induced Oral Mucositis: 11 SNPs Implicated In GWAS Of 972 Patients With Multiple Myeloma Blood. 122: 3316-3316. DOI: 10.1182/Blood.V122.21.3316.3316 |
0.31 |
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| 2013 |
Shao L, Hou D, Feng W, Chang J, Ware J, Hauer-Jensen M, Cheng T, Zhou D. Platelet Depletion Causes Rapid But Transient Activation Of Mouse Bone Marrow Long-Term Hematopoietic Stem Cells To Participate In Stress Thrombopoiesis Blood. 122: 2436-2436. DOI: 10.1182/Blood.V122.21.2436.2436 |
0.352 |
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| 2013 |
Chang J, Wang Y, Shao L, Byrum J, Feng W, Luo Y, Meng A, Chow M, Zhou D. Hematopoietic stem cells from Ts65Dn mouse bone marrow are deficient in the repair of DNA double-strand breaks Experimental Hematology. 41: S32. DOI: 10.1016/J.Exphem.2013.05.126 |
0.359 |
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| 2012 |
Shao L, Wu L, Zhou D. Sensitization of tumor cells to cancer therapy by molecularly targeted inhibition of the inhibitor of nuclear factor κB kinase. Translational Cancer Research. 1: 100-108. PMID 22953243 DOI: 10.3978/J.Issn.2218-676X.2012.05.04 |
0.419 |
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| 2012 |
Geiger H, Pawar SA, Kerschen EJ, Nattamai KJ, Hernandez I, Liang HP, Fernández JÃ, Cancelas JA, Ryan MA, Kustikova O, Schambach A, Fu Q, Wang J, Fink LM, Petersen KU, ... Zhou D, et al. Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. Nature Medicine. 18: 1123-9. PMID 22729286 DOI: 10.1038/Nm.2813 |
0.425 |
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| 2012 |
Shao L, Feng W, Lee KJ, Chen BP, Zhou D. A sensitive and quantitative polymerase chain reaction-based cell free in vitro non-homologous end joining assay for hematopoietic stem cells. Plos One. 7: e33499. PMID 22448248 DOI: 10.1371/Journal.Pone.0033499 |
0.401 |
|
| 2012 |
Diaz-Montero CM, Wang Y, Shao L, Feng W, Zidan AA, Pazoles CJ, Montero AJ, Zhou D. The glutathione disulfide mimetic NOV-002 inhibits cyclophosphamide-induced hematopoietic and immune suppression by reducing oxidative stress. Free Radical Biology & Medicine. 52: 1560-8. PMID 22343421 DOI: 10.1016/J.Freeradbiomed.2012.02.007 |
0.405 |
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| 2012 |
Zou J, Zou P, Wang J, Li L, Wang Y, Zhou D, Liu L. Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells. Annals of Hematology. 91: 813-23. PMID 22258328 DOI: 10.1007/S00277-011-1397-7 |
0.478 |
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| 2011 |
Wang Y, Liu L, Zhou D. Inhibition of p38 MAPK attenuates ionizing radiation-induced hematopoietic cell senescence and residual bone marrow injury. Radiation Research. 176: 743-52. PMID 22014293 DOI: 10.1667/Rr2727.1 |
0.5 |
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| 2011 |
Li D, Wang Y, Wu H, Lu L, Zhang H, Chang J, Zhai Z, Zhang J, Wang Y, Zhou D, Meng A. Mitigation of ionizing radiation-induced bone marrow suppression by p38 inhibition and G-CSF administration. Journal of Radiation Research. 52: 712-6. PMID 21971035 DOI: 10.1269/Jrr.11007 |
0.495 |
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| 2011 |
Luo Y, Zou P, Zou J, Wang J, Zhou D, Liu L. Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKα dependent manner. Experimental Gerontology. 46: 860-7. PMID 21816217 DOI: 10.1016/J.Exger.2011.07.005 |
0.505 |
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| 2011 |
Shao L, Li H, Pazhanisamy SK, Meng A, Wang Y, Zhou D. Reactive oxygen species and hematopoietic stem cell senescence. International Journal of Hematology. 94: 24-32. PMID 21567162 DOI: 10.1007/S12185-011-0872-1 |
0.472 |
|
| 2011 |
Li H, Wang Y, Pazhanisamy SK, Shao L, Batinic-Haberle I, Meng A, Zhou D. Mn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression. Free Radical Biology & Medicine. 51: 30-7. PMID 21565268 DOI: 10.1016/J.Freeradbiomed.2011.04.016 |
0.478 |
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| 2011 |
Wu L, Shao L, An N, Wang J, Pazhanisamy S, Feng W, Hauer-Jensen M, Miyamoto S, Zhou D. IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. Plos One. 6: e18447. PMID 21490922 DOI: 10.1371/Journal.Pone.0018447 |
0.473 |
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| 2011 |
Pazhanisamy SK, Li H, Wang Y, Batinic-Haberle I, Zhou D. NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability. Mutagenesis. 26: 431-5. PMID 21415439 DOI: 10.1093/Mutage/Ger001 |
0.417 |
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| 2011 |
Wang Y, Kellner J, Liu L, Zhou D. Inhibition of p38 mitogen-activated protein kinase promotes ex vivo hematopoietic stem cell expansion. Stem Cells and Development. 20: 1143-52. PMID 21198398 DOI: 10.1089/Scd.2010.0413 |
0.514 |
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| 2011 |
Berbee M, Fu Q, Boerma M, Pathak R, Zhou D, Kumar KS, Hauer-Jensen M. Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. International Journal of Radiation Oncology, Biology, Physics. 79: 884-91. PMID 20950957 DOI: 10.1016/J.Ijrobp.2010.08.032 |
0.353 |
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| 2011 |
Shao L, Feng W, Zhou D. A Sensitive and Quantitative Polymerase Chain Reaction-Based Non-Homologous End Joining in Vitro Assay for Hematopoietic Stem Cells Blood. 118: 4825-4825. DOI: 10.1182/Blood.V118.21.4825.4825 |
0.388 |
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| 2011 |
Shao L, Feng W, Li H, Wang Y, Sharpless N, Zhou D. Ionizing Radiation Induces Hematopoietic Stem Cell Senescence and Long-Term Bone Marrow Suppression in a p16Ink4a/Arf-Independent manner Blood. 118: 1345-1345. DOI: 10.1182/Blood.V118.21.1345.1345 |
0.493 |
|
| 2010 |
Johnson SM, Torrice CD, Bell JF, Monahan KB, Jiang Q, Wang Y, Ramsey MR, Jin J, Wong KK, Su L, Zhou D, Sharpless NE. Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition. The Journal of Clinical Investigation. 120: 2528-36. PMID 20577054 DOI: 10.1172/Jci41402 |
0.492 |
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| 2010 |
Wang Y, Liu L, Pazhanisamy SK, Li H, Meng A, Zhou D. Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells. Free Radical Biology & Medicine. 48: 348-56. PMID 19925862 DOI: 10.1182/Blood.V114.22.3209.3209 |
0.459 |
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| 2009 |
Wang Y, Kellner J, Zhou D. Inhibition of p38 MAPK Promotes Hematopoietic Stem Cells Self-Renewal and Ex Vivo Expansion. Blood. 114: 34-34. DOI: 10.1182/Blood.V114.22.34.34 |
0.502 |
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| 2009 |
Pazhanisamy SK, An N, Wang Y, Zhou D. Hematopoietic Stem Cells Repair Ionizing Radiation-Induced DNA Double Strand Breaks in a Cell Cycle-Dependent Manner. Blood. 114: 3241-3241. DOI: 10.1182/Blood.V114.22.3241.3241 |
0.415 |
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| 2007 |
Probin V, Wang Y, Zhou D. Busulfan-induced senescence is dependent on ROS production upstream of the MAPK pathway. Free Radical Biology & Medicine. 42: 1858-65. PMID 17512465 DOI: 10.1016/J.Freeradbiomed.2007.03.020 |
0.76 |
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| 2007 |
Liu L, Wang Y, Zhou D. Inhibition of p38 MAPK Reduces Ionizing Radiation (IR)-Induced Hematopoietic Suppression by Preventing Hematopoietic Stem/Progenitor Cell Senescence. Blood. 110: 4042-4042. DOI: 10.1182/Blood.V110.11.4042.4042 |
0.576 |
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| 2006 |
Wang Y, Probin V, Zhou D. Cancer therapy-induced residual bone marrow injury-Mechanisms of induction and implication for therapy. Current Cancer Therapy Reviews. 2: 271-279. PMID 19936034 DOI: 10.2174/157339406777934717 |
0.734 |
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| 2006 |
Probin V, Wang Y, Bai A, Zhou D. Busulfan selectively induces cellular senescence but not apoptosis in WI38 fibroblasts via a p53-independent but extracellular signal-regulated kinase-p38 mitogen-activated protein kinase-dependent mechanism. The Journal of Pharmacology and Experimental Therapeutics. 319: 551-60. PMID 16882877 DOI: 10.1124/Jpet.106.107771 |
0.759 |
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| 2006 |
Lang H, Schulte BA, Zhou D, Smythe N, Spicer SS, Schmiedt RA. Nuclear factor κB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss Journal of Neuroscience. 26: 3541-3550. PMID 16571762 DOI: 10.1523/Jneurosci.2488-05.2006 |
0.338 |
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| 2006 |
Lang H, Ebihara Y, Schmiedt RA, Minamiguchi H, Zhou D, Smythe N, Liu L, Ogawa M, Schulte BA. Contribution of bone marrow hematopoietic stem cells to adult mouse inner ear: Mesenchymal cells and fibrocytes Journal of Comparative Neurology. 496: 187-201. PMID 16538683 DOI: 10.1002/Cne.20929 |
0.389 |
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| 2006 |
Wang Y, Schulte BA, Zhou D. Hematopoietic stem cell senescence and long-term bone marrow injury. Cell Cycle (Georgetown, Tex.). 5: 35-8. PMID 16319536 DOI: 10.4161/Cc.5.1.2280 |
0.453 |
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| 2006 |
Kawamori T, Osta W, Johnson KR, Pettus BJ, Bielawski J, Tanaka T, Wargovich MJ, Reddy BS, Hannun YA, Obeid LM, Zhou D. Sphingosine kinase 1 is up-regulated in colon carcinogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 386-8. PMID 16319132 DOI: 10.1096/Fj.05-4331Fje |
0.369 |
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| 2006 |
Wang Y, Schulte BA, LaRue AC, Ogawa M, Zhou D. Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood. 107: 358-66. PMID 16150936 DOI: 10.1182/Blood-2005-04-1418 |
0.513 |
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| 2006 |
Liu L, Zhou D, Wang Y. Inhibition of p38 MAPK Reduces Ionizing Radiation-Induced Hematopoietic Cell Injury. Blood. 108: 4181-4181. DOI: 10.1182/Blood.V108.11.4181.4181 |
0.571 |
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| 2006 |
Probin V, Bai A, Zhou D, Wang Y. Busulfan Selectively Induces Cellular Senescence Via a p53-Independent but Erk-p38 MAPK-Dependent Mechanism. Blood. 108: 3199-3199. DOI: 10.1182/Blood.V108.11.3199.3199 |
0.768 |
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| 2005 |
Wang Y, Schulte BA, LaRue AC, Ogawa M, Zhou D. Induction of Hematopoietic Stem Cell Senescence by Ionizing Radiation. Blood. 106: 1362-1362. DOI: 10.1182/Blood.V106.11.1362.1362 |
0.531 |
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| 2004 |
Wang Y, Meng A, Lang H, Brown SA, Konopa JL, Kindy MS, Schmiedt RA, Thompson JS, Zhou D. Activation of nuclear factor kappaB In vivo selectively protects the murine small intestine against ionizing radiation-induced damage. Cancer Research. 64: 6240-6. PMID 15342410 DOI: 10.1158/0008-5472.Can-04-0591 |
0.45 |
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| 2004 |
Wang Y, Meng A, Zhou D. Inhibition of phosphatidylinostol 3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts. Experimental Cell Research. 298: 188-96. PMID 15242773 DOI: 10.1016/J.Yexcr.2004.04.012 |
0.466 |
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| 2004 |
Meng A, Luberto C, Meier P, Bai A, Yang X, Hannun YA, Zhou D. Sphingomyelin synthase as a potential target for D609-induced apoptosis in U937 human monocytic leukemia cells. Experimental Cell Research. 292: 385-92. PMID 14697345 DOI: 10.1016/J.Yexcr.2003.10.001 |
0.399 |
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| 2004 |
Brown S, Konopa J, Zhou D, Thompson J. Expression of TNFα by CD3+ and F4/80+ cells following irradiation preconditioning and allogeneic spleen cell transplantation Bone Marrow Transplantation. 33: 359-365. PMID 14676780 DOI: 10.1038/Sj.Bmt.1704362 |
0.322 |
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| 2003 |
Meng A, Yu T, Chen G, Brown SA, Wang Y, Thompson JS, Zhou D. Cellular origin of ionizing radiation‐induced NF‐κB activation in vivo and role of NF‐κB in ionizing radiation‐induced lymphocyte apoptosis International Journal of Radiation Biology. 79: 849-861. PMID 14698954 DOI: 10.1080/09553000310001622814 |
0.385 |
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| 2003 |
Meng A, Wang Y, Brown SA, Van Zant G, Zhou D. Ionizing radiation and busulfan inhibit murine bone marrow cell hematopoietic function via apoptosis-dependent and -independent mechanisms. Experimental Hematology. 31: 1348-56. PMID 14662344 DOI: 10.1016/J.Exphem.2003.08.014 |
0.406 |
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| 2003 |
Meng A, Wang Y, Van Zant G, Zhou D. Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells. Cancer Research. 63: 5414-9. PMID 14500376 |
0.438 |
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| 2002 |
Cheng G, Yu Z, Zhou D, Mattson MP. Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein. Experimental Neurology. 175: 407-14. PMID 12061870 DOI: 10.1006/Exnr.2002.7920 |
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| 1999 |
Zhou D, Brown SA, Yu T, Chen G, Barve S, Kang BC, Thompson JS. A high dose of ionizing radiation induces tissue-specific activation of nuclear factor-kappaB in vivo. Radiation Research. 151: 703-709. DOI: 10.2307/3580209 |
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| 1999 |
Yu Z, Zhou D, Bruce-Keller AJ, Kindy MS, Mattson MP. Lack of the p50 Subunit of Nuclear Factor-κB Increases the Vulnerability of Hippocampal Neurons to Excitotoxic Injury The Journal of Neuroscience. 19: 8856-8865. DOI: 10.1523/Jneurosci.19-20-08856.1999 |
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