Year |
Citation |
Score |
2023 |
Noonan JD, Beech RN. Two residues determine nicotinic acetylcholine receptor requirement for RIC-3. Protein Science : a Publication of the Protein Society. 32: e4718. PMID 37417463 DOI: 10.1002/pro.4718 |
0.348 |
|
2021 |
Kaji MD, Noonan JD, Geary TG, Beech RN. Structural mechanism underlying the differential effects of ivermectin and moxidectin on the C. elegans glutamate-gated chloride channel GLC-2. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 145: 112380. PMID 34749053 DOI: 10.1016/j.biopha.2021.112380 |
0.435 |
|
2018 |
Blanchard A, Guégnard F, Charvet CL, Crisford A, Courtot E, Sauvé C, Harmache A, Duguet T, O'Connor V, Castagnone-Sereno P, Reaves B, Wolstenholme AJ, Beech RN, Holden-Dye L, Neveu C. Deciphering the molecular determinants of cholinergic anthelmintic sensitivity in nematodes: When novel functional validation approaches highlight major differences between the model Caenorhabditis elegans and parasitic species. Plos Pathogens. 14: e1006996. PMID 29719008 DOI: 10.1371/journal.ppat.1006996 |
0.332 |
|
2018 |
David M, Lebrun C, Duguet T, Talmont F, Beech R, Orlowski S, André F, Prichard RK, Lespine A. Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13. International Journal For Parasitology. Drugs and Drug Resistance. 8: 145-157. PMID 29571165 DOI: 10.1016/J.Ijpddr.2018.02.001 |
0.345 |
|
2017 |
Ishii JB, Arenal A, Felix A, Yoshitani U, Beech R, Molento MB. Diagnosis of resistance alleles in codon 167 of the beta-tubulin (Cya-tbb-1) gene from third-stage larvae of horse cyathostomins. Research in Veterinary Science. 115: 92-95. PMID 28199900 DOI: 10.1016/J.Rvsc.2017.01.019 |
0.311 |
|
2016 |
Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, et al. The genome of Onchocerca volvulus, agent of river blindness. Nature Microbiology. 2: 16216. PMID 27869790 DOI: 10.1038/Nmicrobiol.2016.216 |
0.313 |
|
2016 |
Duguet TB, Charvet CL, Forrester SG, Wever CM, Dent JA, Neveu C, Beech RN. Recent Duplication and Functional Divergence in Parasitic Nematode Levamisole-Sensitive Acetylcholine Receptors. Plos Neglected Tropical Diseases. 10: e0004826. PMID 27415016 DOI: 10.1371/Journal.Pntd.0004826 |
0.702 |
|
2015 |
Courtot E, Charvet CL, Beech RN, Harmache A, Wolstenholme AJ, Holden-Dye L, O'Connor V, Peineau N, Woods DJ, Neveu C. Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes. Plos Pathogens. 11: e1005267. PMID 26625142 DOI: 10.1371/journal.ppat.1005267 |
0.426 |
|
2015 |
Ashraf S, Mani T, Beech R, Prichard R. Macrocyclic lactones and their relationship to the SNPs related to benzimidazole resistance. Molecular and Biochemical Parasitology. 201: 128-34. PMID 26253426 DOI: 10.1016/J.Molbiopara.2015.07.007 |
0.365 |
|
2015 |
Lynagh T, Beech RN, Lalande MJ, Keller K, Cromer BA, Wolstenholme AJ, Laube B. Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels. Scientific Reports. 5: 8558. PMID 25708000 DOI: 10.1038/srep08558 |
0.341 |
|
2015 |
Beech RN, Neveu C. The evolution of pentameric ligand-gated ion-channels and the changing family of anthelmintic drug targets. Parasitology. 142: 303-17. PMID 25354656 DOI: 10.1017/S003118201400170X |
0.364 |
|
2015 |
Baur R, Beech R, Sigel E, Rufener L. Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors. Molecular Pharmacology. 87: 96-102. PMID 25352042 DOI: 10.1124/mol.114.095653 |
0.417 |
|
2014 |
Urdaneta-Marquez L, Bae SH, Janukavicius P, Beech R, Dent J, Prichard R. A dyf-7 haplotype causes sensory neuron defects and is associated with macrocyclic lactone resistance worldwide in the nematode parasite Haemonchus contortus. International Journal For Parasitology. 44: 1063-71. PMID 25224687 DOI: 10.1016/J.Ijpara.2014.08.005 |
0.342 |
|
2013 |
Dufour V, Beech RN, Wever C, Dent JA, Geary TG. Molecular cloning and characterization of novel glutamate-gated chloride channel subunits from Schistosoma mansoni. Plos Pathogens. 9: e1003586. PMID 24009509 DOI: 10.1371/journal.ppat.1003586 |
0.452 |
|
2013 |
Rufener L, Bedoni N, Baur R, Rey S, Glauser DA, Bouvier J, Beech R, Sigel E, Puoti A. acr-23 Encodes a monepantel-sensitive channel in Caenorhabditis elegans. Plos Pathogens. 9: e1003524. PMID 23950710 DOI: 10.1371/Journal.Ppat.1003524 |
0.446 |
|
2013 |
Beech RN, Callanan MK, Rao VT, Dawe GB, Forrester SG. Characterization of cys-loop receptor genes involved in inhibitory amine neurotransmission in parasitic and free living nematodes. Parasitology International. 62: 599-605. PMID 23602737 DOI: 10.1016/J.Parint.2013.03.010 |
0.734 |
|
2013 |
Saunders GI, Wasmuth JD, Beech R, Laing R, Hunt M, Naghra H, Cotton JA, Berriman M, Britton C, Gilleard JS. Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes. International Journal For Parasitology. 43: 465-75. PMID 23416426 DOI: 10.1016/J.Ijpara.2012.12.011 |
0.407 |
|
2012 |
Martin RJ, Robertson AP, Buxton SK, Beech RN, Charvet CL, Neveu C. Levamisole receptors: a second awakening. Trends in Parasitology. 28: 289-96. PMID 22607692 DOI: 10.1016/j.pt.2012.04.003 |
0.371 |
|
2012 |
Accardi MV, Beech RN, Forrester SG. Nematode cys-loop GABA receptors: biological function, pharmacology and sites of action for anthelmintics. Invertebrate Neuroscience : In. 12: 3-12. PMID 22430311 DOI: 10.1007/S10158-012-0129-6 |
0.705 |
|
2010 |
Neveu C, Charvet CL, Fauvin A, Cortet J, Beech RN, Cabaret J. Genetic diversity of levamisole receptor subunits in parasitic nematode species and abbreviated transcripts associated with resistance. Pharmacogenetics and Genomics. 20: 414-25. PMID 20531256 DOI: 10.1097/FPC.0b013e328338ac8c |
0.303 |
|
2010 |
Beech RN, Wolstenholme AJ, Neveu C, Dent JA. Nematode parasite genes: what's in a name? Trends in Parasitology. 26: 334-40. PMID 20478743 DOI: 10.1016/j.pt.2010.04.003 |
0.317 |
|
2010 |
Rao VT, Accardi MV, Siddiqui SZ, Beech RN, Prichard RK, Forrester SG. Characterization of a novel tyramine-gated chloride channel from Haemonchus contortus. Molecular and Biochemical Parasitology. 173: 64-8. PMID 20471431 DOI: 10.1016/J.Molbiopara.2010.05.005 |
0.733 |
|
2010 |
Beech R, Levitt N, Cambos M, Zhou S, Forrester SG. Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus. Molecular and Biochemical Parasitology. 171: 74-80. PMID 20211658 DOI: 10.1016/J.Molbiopara.2010.02.004 |
0.707 |
|
2008 |
Morissette DC, Dauch A, Beech R, Masson L, Brousseau R, Jabaji-Hare S. Isolation of mycoparasitic-related transcripts by SSH during interaction of the mycoparasite Stachybotrys elegans with its host Rhizoctonia solani. Current Genetics. 53: 67-80. PMID 18058103 DOI: 10.1007/S00294-007-0166-6 |
0.338 |
|
2004 |
Forrester SG, Beech RN, Prichard RK. Agonist enhacement of macrocyclic lactone activity at a glutamate-gated chloride channel subunit from Haemonchus contortus. Biochemical Pharmacology. 67: 1019-24. PMID 15006538 DOI: 10.1016/J.Bcp.2003.08.047 |
0.728 |
|
2003 |
Forrester SG, Prichard RK, Dent JA, Beech RN. Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin. Molecular and Biochemical Parasitology. 129: 115-21. PMID 12798512 DOI: 10.1016/S0166-6851(03)00102-6 |
0.719 |
|
2002 |
Forrester SG, Prichard RK, Beech RN. A glutamate-gated chloride channel subunit from Haemonchus contortus: expression in a mammalian cell line, ligand binding, and modulation of anthelmintic binding by glutamate. Biochemical Pharmacology. 63: 1061-8. PMID 11931838 DOI: 10.1016/S0006-2952(02)00852-3 |
0.719 |
|
1999 |
Forrester SG, Hamdan FF, Prichard RK, Beech RN. Cloning, sequencing, and developmental expression levels of a novel glutamate-gated chloride channel homologue in the parasitic nematode Haemonchus contortus. Biochemical and Biophysical Research Communications. 254: 529-34. PMID 9920773 DOI: 10.1006/Bbrc.1998.0106 |
0.728 |
|
1998 |
Blackhall WJ, Pouliot JF, Prichard RK, Beech RN. Haemonchus contortus: selection at a glutamate-gated chloride channel gene in ivermectin- and moxidectin-selected strains. Experimental Parasitology. 90: 42-8. PMID 9709029 DOI: 10.1006/expr.1998.4316 |
0.315 |
|
1998 |
Xu M, Molento M, Blackhall W, Ribeiro P, Beech R, Prichard R. Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog. Molecular and Biochemical Parasitology. 91: 327-35. PMID 9566525 DOI: 10.1016/S0166-6851(97)00215-6 |
0.369 |
|
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