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Richard E. Taylor - Publications

Affiliations: 
Chemistry and Biochemistry University of Notre Dame, Notre Dame, IN, United States 
Area:
polyketide natural products
Website:
http://chemistry.nd.edu/faculty/detail/rtaylor/
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77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Taylor RE, Trentadue K, Chang CF, Nalin A. Enantioselective Total Synthesis of the Putative Biosynthetic Intermediate Ambruticin J. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33887073 DOI: 10.1002/chem.202100975  0.321
2019 Henry JL, Wilson MR, Mulligan MP, Quinn TR, Sackett DL, Taylor RE. Synthesis, conformational preferences, and biological activity of conformational analogues of the microtubule-stabilizing agents, (-)-zampanolide and (-)-dactylolide. Medchemcomm. 10: 800-805. PMID 31191870 DOI: 10.1039/C9Md00164F  0.499
2018 Granatosky EA, DiPrimio N, Pickering JRE, Stevens DC, Perlstein EO, Taylor RE. GEX1A, a Polyketide from Streptomyces chromofuscus, Corrects the Cellular Defects Associated with Niemann-Pick Type C1 in Human Fibroblasts. Journal of Natural Products. PMID 30188717 DOI: 10.1021/Acs.Jnatprod.8B00314  0.529
2018 Dodge GJ, Ronnow D, Taylor RE, Smith JL. Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase. Acs Chemical Biology. PMID 30179448 DOI: 10.1021/Acschembio.8B00645  0.353
2018 Larsen EM, Chang CF, Sakata-Kato T, Arico JW, Lombardo VM, Wirth DF, Taylor RE. Conformation-guided analogue design identifies potential antimalarial compounds through inhibition of mitochondrial respiration. Organic & Biomolecular Chemistry. PMID 30009295 DOI: 10.1039/C8Ob01257A  0.353
2017 Woods LM, Arico JW, Frein JD, Sackett DL, Taylor RE. Synthesis and Biological Evaluation of 7-Deoxy-Epothilone Analogues. International Journal of Molecular Sciences. 18. PMID 28304361 DOI: 10.3390/Ijms18030648  0.336
2016 Wagner DT, Stevens DC, Mehaffey MR, Manion HR, Taylor RE, Brodbelt JS, Keatinge-Clay AT. α-Methylation follows condensation in the gephyronic acid modular polyketide synthase. Chemical Communications (Cambridge, England). PMID 27346052 DOI: 10.1039/C6Cc04418B  0.721
2015 Chang CF, Stefan E, Taylor RE. Total Synthesis and Structural Reassignment of Lyngbyaloside C Highlighted by Intermolecular Ketene Esterification. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 10681-6. PMID 26101039 DOI: 10.1002/Chem.201502132  0.693
2015 Larsen EM, Wilson MR, Taylor RE. Conformation-activity relationships of polyketide natural products. Natural Product Reports. 32: 1183-206. PMID 25974024 DOI: 10.1039/C5Np00014A  0.456
2015 Naini A, Muthukumar Y, Raja A, Franke R, Harrier I, Smith AB, Lee D, Taylor RE, Sasse F, Kalesse M. The synthesis and biological evaluation of desepoxyisotedanolide and a comparison with desepoxytedanolide. Angewandte Chemie (International Ed. in English). 54: 6935-9. PMID 25914374 DOI: 10.1002/Anie.201501526  0.753
2015 Stefan E, Taylor RE. 1,5-Hydride transfer protocol for the synthesis of β-branched polyketide structural units Tetrahedron Letters. 56: 3416-3419. DOI: 10.1016/J.Tetlet.2015.01.020  0.667
2015 Naini A, Muthukumar Y, Raja A, Franke R, Harrier I, Smith AB, Lee D, Taylor RE, Sasse F, Kalesse M. Die Synthese und biologische Validierung von Desepoxyisotedanolid und dessen Vergleich mit Desepoxytedanolid Angewandte Chemie. 127: 7039-7043. DOI: 10.1002/Ange.201501526  0.72
2014 Stevens DC, Young J, Carmichael R, Tan J, Taylor RE. Draft Genome Sequence of Gephyronic Acid Producer Cystobacter violaceus Strain Cb vi76. Genome Announcements. 2. PMID 25502681 DOI: 10.1128/Genomea.01299-14  0.645
2013 Young J, Stevens DC, Carmichael R, Tan J, Rachid S, Boddy CN, Müller R, Taylor RE. Elucidation of gephyronic acid biosynthetic pathway revealed unexpected SAM-dependent methylations. Journal of Natural Products. 76: 2269-76. PMID 24298873 DOI: 10.1021/Np400629V  0.755
2013 Larsen EM, Wilson MR, Zajicek J, Taylor RE. Conformational preferences of zampanolide and dactylolide. Organic Letters. 15: 5246-9. PMID 24102367 DOI: 10.1021/Ol402462H  0.393
2013 Stefan E, Nalin AP, Taylor RE. Concise enantioselective synthesis of diospongins A and B. Tetrahedron. 69: 7706-7712. PMID 24058215 DOI: 10.1016/J.Tet.2013.05.081  0.674
2013 Wilson MR, Taylor RE. Strained alkenes in natural product synthesis. Angewandte Chemie (International Ed. in English). 52: 4078-87. PMID 23450661 DOI: 10.1002/Anie.201207712  0.442
2013 Muthukumar Y, Roy M, Raja A, Taylor RE, Sasse F. The marine polyketide myriaporone 3/4 stalls translation by targeting the elongation phase. Chembiochem : a European Journal of Chemical Biology. 14: 260-4. PMID 23303710 DOI: 10.1002/Cbic.201200522  0.523
2013 Wilson MR, Taylor RE. Gespannte Moleküle in der Naturstoffsynthese Angewandte Chemie. 125: 4170-4180. DOI: 10.1002/Ange.201207712  0.364
2012 Wilson MR, Taylor RE. Toward an enantioselective synthesis of (-)-zampanolide: preparation of the C9-C20 region. Organic Letters. 14: 3408-11. PMID 22720980 DOI: 10.1021/Ol301383A  0.518
2012 Stefan E, Taylor RE. Stereoselective synthesis of the C9-C19 fragment of lyngbyaloside B and C via ether transfer. Organic Letters. 14: 3490-3. PMID 22716968 DOI: 10.1021/Ol301455P  0.649
2012 Zhao Z, Taylor RE. Rapid access to conformational analogues of (+)-peloruside A. Organic Letters. 14: 669-71. PMID 22235754 DOI: 10.1021/Ol203268T  0.356
2011 Anderl T, Nicolas L, Münkemer J, Baro A, Sasse F, Steinmetz H, Jansen R, Höfle G, Taylor RE, Laschat S. Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part II): Total synthesis of gephyronic acid. Angewandte Chemie (International Ed. in English). 50: 942-5. PMID 21246697 DOI: 10.1002/Anie.201005605  0.611
2011 Nicolas L, Anderl T, Sasse F, Steinmetz H, Jansen R, Höfle G, Laschat S, Taylor RE. Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part I): Structural revision and stereochemical assignment of gephyronic acid. Angewandte Chemie (International Ed. in English). 50: 938-41. PMID 21246696 DOI: 10.1002/Anie.201005530  0.604
2011 Young J, Leliaert A, Schafer ZT, Taylor RE. Abstract C67: Gene expression profiling with human breast cancer cell lines exposed to gephyronic acid Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C67  0.546
2011 Anderl T, Nicolas L, Münkemer J, Muthukumar Y, Baro A, Frey W, Sasse F, Taylor RE, Laschat S. Synthesis and biological evaluation of gephyronic acid derivatives: Initial steps towards the identification of the biological target of polyketide inhibitors of eukaryotic protein synthesis European Journal of Organic Chemistry. 7294-7307. DOI: 10.1002/Ejoc.201101129  0.659
2010 Liu K, Arico JW, Taylor RE. Application of stereoselective ether transfer to the synthesis of isotactic polyethers. The Journal of Organic Chemistry. 75: 3953-7. PMID 20481506 DOI: 10.1021/Jo100094D  0.399
2010 Anderl T, Nicolas L, Münkemer J, Baro A, Sasse F, Steinmetz H, Jansen R, Höfle G, Taylor RE, Laschat S. Gephyronsäure, ein fehlendes Bindeglied zwischen Polyketid-Inhibitoren der eukaryotischen Proteinsynthese (Teil II): Totalsynthese Angewandte Chemie. 123: 972-975. DOI: 10.1002/Ange.201005605  0.523
2010 Nicolas L, Anderl T, Sasse F, Steinmetz H, Jansen R, Höfle G, Laschat S, Taylor RE. Gephyronsäure, ein fehlendes Bindeglied zwischen Polyketid- Inhibitoren der eukaryotischen Proteinsynthese (Teil I): Strukturrevision und stereochemische Zuordnung Angewandte Chemie. 123: 968-971. DOI: 10.1002/Ange.201005530  0.549
2009 Frein JD, Taylor RE, Sackett DL. New sources of chemical diversity inspired by biosynthesis: rational design of a potent epothilone analogue. Organic Letters. 11: 3186-9. PMID 19572566 DOI: 10.1021/Ol900971R  0.302
2009 Daly EM, Taylor RE. Entropy and enthalpy in the activity of Tubulin-based antimitotic agents Current Chemical Biology. 3: 47-59. DOI: 10.2174/2212796810903010047  0.586
2008 Kartika R, Gruffi TR, Taylor RE. Concise enantioselective total synthesis of neopeltolide macrolactone highlighted by ether transfer. Organic Letters. 10: 5047-50. PMID 18855401 DOI: 10.1021/Ol802254Z  0.733
2008 Taylor RE. Tedanolide and the evolution of polyketide inhibitors of eukaryotic protein synthesis. Natural Product Reports. 25: 854-61. PMID 18820754 DOI: 10.1039/B805700C  0.342
2008 Young J, Taylor RE. Evolution of polyketides: post-PKS processing in the formation of spiroketals. Natural Product Reports. 25: 651-5. PMID 18663388 DOI: 10.1039/B719088N  0.54
2008 Kartika R, Frein JD, Taylor RE. Electrophile-induced ether transfer: stereoselective synthesis of 2,6-disubstituted-3,4-dihydropyrans. The Journal of Organic Chemistry. 73: 5592-4. PMID 18570473 DOI: 10.1021/Jo800704D  0.735
2007 Kartika R, Taylor RE. Electrophile-induced ether transfer: stereoselective synthesis of 2,4,6-trisubstituted tetrahydropyrans. Angewandte Chemie (International Ed. in English). 46: 6874-7. PMID 17674386 DOI: 10.1002/Anie.200702018  0.736
2007 Melancon BJ, Perl NR, Taylor RE. Competitive cationic pathways and the asymmetric synthesis of aryl-substituted cyclopropanes. Organic Letters. 9: 1425-8. PMID 17362019 DOI: 10.1021/Ol063026P  0.397
2007 Kartika R, Taylor RE. Electrophile-induced ether transfer: An expedient route to 2-cyano-tetrahydropyrans Heterocycles. 74: 447-459. DOI: 10.3987/Com-07-S(W)23  0.706
2007 Tung JC, Chen W, Noll BC, Taylor RE, Fields SC, Dent WH, Green FR. Towards the synthesis of the cornexistins Synthesis. 2388-2396. DOI: 10.1055/S-2007-983769  0.637
2007 Daly EM, Taylor RE. Recent applications of the Nozaki-Hiyama-Kishi reaction in natural product synthesis Chemtracts. 20: 1-8.  0.619
2007 Kartika R, Taylor RE. An exhaustive hydrogenation strategy to bicyclic alkaloids Chemtracts. 19: 385-390.  0.617
2006 Liu K, Taylor RE, Kartika R. Electrophile-induced ether transfer: a new approach to polyketide structural units. Organic Letters. 8: 5393-5. PMID 17078726 DOI: 10.1021/Ol0623318  0.722
2006 Hines J, Roy M, Cheng H, Agapakis CM, Taylor R, Crews CM. Myriaporone 3/4 structure--activity relationship studies define a pharmacophore targeting eukaryotic protein synthesis. Molecular Biosystems. 2: 371-9. PMID 16880957 DOI: 10.1039/B602936A  0.517
2005 Jin M, Taylor RE. Total synthesis of (+)-peloruside A. Organic Letters. 7: 1303-5. PMID 15787492 DOI: 10.1021/Ol050070G  0.405
2005 Taylor RE, Fleming KN, Hearn BR. Chapter 8 Total synthesis of myriaporones 1, 3, and 4 Strategies and Tactics in Organic Synthesis. 6: 246-268. DOI: 10.1016/S1874-6004(05)80031-0  0.789
2005 Paquette WD, Taylor RE. Conformationally biased macrolactonizations Chemtracts. 18: 584-590.  0.734
2004 Risatti CA, Taylor RE. Enantioselective synthesis of cyclopropanes by aldehyde homologation. Angewandte Chemie (International Ed. in English). 43: 6671-2. PMID 15593156 DOI: 10.1002/Anie.200461106  0.795
2004 Suckow MA, Gutierrez LS, Risatti CA, Wolter WR, Taylor RE, Pollard M, Navari RM, Castellino FJ, Paoni NF. The anti-ischemia agent ranolazine promotes the development of intestinal tumors in APC(Min/+) mice. Cancer Letters. 209: 165-9. PMID 15159018 DOI: 10.1016/J.Canlet.2004.01.007  0.726
2004 Fleming KN, Taylor RE. Total synthesis and stereochemical assignment of myriaporones 1, 3, and 4. Angewandte Chemie (International Ed. in English). 43: 1728-30. PMID 15038050 DOI: 10.1002/Anie.200353348  0.728
2004 Taylor RE, Chen Y, Galvin GM, Pabba PK. Conformation-activity relationships in polyketide natural products. Towards the biologically active conformation of epothilone. Organic & Biomolecular Chemistry. 2: 127-32. PMID 14737671 DOI: 10.1039/B312213C  0.766
2004 Paquette WD, Taylor RE. Enantioselective preparation of the C1-C11 fragment of apoptolidin. Organic Letters. 6: 103-6. PMID 14703361 DOI: 10.1021/Ol0361397  0.791
2004 Risatti CA, Taylor RE. Biomimetic Synthesis of Polycyclic Natural Products from Acyclic Precursors Chemtracts. 17: 83-91.  0.771
2003 Taylor RE, Jin M. Toward a total synthesis of peloruside A: enantioselective preparation of the C8-C19 region. Organic Letters. 5: 4959-61. PMID 14682739 DOI: 10.1021/Ol0358814  0.374
2003 Yoshimura F, Rivkin A, Gabarda AE, Chou TC, Dong H, Sukenick G, Morel FF, Taylor RE, Danishefsky SJ. Synthesis and conformational analysis of (E)-9,10-dehydroepothilone B: a suggestive link between the chemistry and biology of epothilones. Angewandte Chemie (International Ed. in English). 42: 2518-21. PMID 12800175 DOI: 10.1002/Anie.200351407  0.308
2003 Taylor RE, Risatti CA, Engelhardt FC, Schmitt MJ. Cyclopropane structural units from homoaldol adducts. Organic Letters. 5: 1377-9. PMID 12688763 DOI: 10.1021/Ol034448R  0.773
2003 Taylor RE, Chen Y, Beatty A, Myles DC, Zhou Y. Conformation-activity relationships in polyketide natural products: a new perspective on the rational design of epothilone analogues. Journal of the American Chemical Society. 125: 26-7. PMID 12515494 DOI: 10.1021/Ja028196L  0.324
2003 Taylor RE, Engelhardt FC, Schmitt MJ. Biosynthetic inspirations: Cationic approaches to cyclopropane formation Tetrahedron. 59: 5623-5634. DOI: 10.1016/S0040-4020(03)00880-9  0.723
2003 Brown AV, Taylor RE. Lewis acid induced epoxide rearrangement for complex molecule synthesis Chemtracts. 16: 254-258.  0.593
2002 Taylor RE, Hearn BR, Ciavarri JP. A divergent approach to the myriaporones and tedanolide: completion of the carbon skeleton of myriaporone 1. Organic Letters. 4: 2953-5. PMID 12182597 DOI: 10.1021/Ol026356S  0.772
2001 Taylor RE, Chen Y. Total synthesis of epothilones B and D Organic Letters. 3: 2221-2223. PMID 11440584 DOI: 10.1021/Ol010094X  0.381
2001 Engelhardt FC, Schmitt MJ, Taylor RE. Kinetically controlled cross-metathesis reactions with high E-olefin selectivities. Organic Letters. 3: 2209-12. PMID 11440581 DOI: 10.1021/Ol016061Z  0.702
2001 Taylor RE, Engelhardt FC, Schmitt MJ, Yuan H. Synthetic methodology for the construction of structurally diverse cyclopropanes Journal of the American Chemical Society. 123: 2964-2969. DOI: 10.1021/Ja0037163  0.7
2000 Taylor RE, Schmitt MJ, Yuan H. Structural diversity based on cyclopropane scaffolds Organic Letters. 2: 601-3. PMID 10814388 DOI: 10.1021/Ol9913542  0.5
1999 Taylor RE, Conrad Engelhardt F, Yuan H. Oligocyclopropane structural units from cationic intermediates Organic Letters. 1: 1257-1260. DOI: 10.1021/Ol990221D  0.417
1999 Taylor RE, Zajicek J. Conformational properties of epothilone Journal of Organic Chemistry. 64: 7224-7228. DOI: 10.1021/Jo991014U  0.319
1999 Taylor RE, Ciavarri JP. 2-bromoallyl acetate: A useful structural unit for sequential carbon-carbon bond formation Organic Letters. 1: 467-469.  0.729
1998 Taylor RE, Galvin GM, Hilfiker KA, Chen Y. A formal total synthesis of epothilone A: Enantioselective preparation of the C1-C6 and C7-C12 fragments Journal of Organic Chemistry. 63: 9580-9583. DOI: 10.1021/Jo981461U  0.811
1998 Taylor RE, Ciavarri JP, Hearn BR. A divergent approach to the myriaporones and tedanolide: Enantioselective preparation of the common intermediate Tetrahedron Letters. 39: 9361-9364. DOI: 10.1016/S0040-4039(98)02110-8  0.798
1998 Patterson S, Smith BD, Taylor RE. Tuning the affinity of a synthetic sialic acid receptor using combinatorial chemistry Tetrahedron Letters. 39: 3111-3114. DOI: 10.1016/S0040-4039(98)00514-0  0.448
1997 Wender PA, Badham NF, Conway SP, Floreancig PE, Glass TE, Houze JB, Krauss NE, Lee D, Marquess DG, McGrane PL, Meng W, Natchus MG, Shuker AJ, Sutton JC, Taylor RE. The pinene path to taxanes. 6. A concise stereocontrolled synthesis of taxol Journal of the American Chemical Society. 119: 2757-2758. DOI: 10.1021/Ja963539Z  0.794
1997 Wender PA, Badham NF, Conway SP, Floreancig PE, Glass TE, Granicher C, Houze JB, Janichen J, Lee D, Marquess DG, McGrane PL, Meng W, Mucciaro TP, Muhlebach M, Natchus MG, ... ... Taylor RE, et al. The pinene path tot taxanes. 5. Stereocontrolled synthesis of a versatile taxane precursor Journal of the American Chemical Society. 119: 2755-2756. DOI: 10.1021/Ja9635387  0.792
1997 Patterson S, Smith BD, Taylor RE. Fluorescence sensing of a ribonucleoside 5'-triphosphate Tetrahedron Letters. 38: 6323-6326. DOI: 10.1016/S0040-4039(97)01454-8  0.423
1997 Taylor RE, Haley JD. Towards the synthesis of epothilone A: Enantioselective preparation of the thiazole side-chain and macrocyclic ring closure Tetrahedron Letters. 38: 2061-2064. DOI: 10.1016/S0040-4039(97)00285-2  0.412
1997 Taylor RE, Ameriks MK, LaMarche MJ. A novel approach to oligocyclopropane structural units Tetrahedron Letters. 38: 2057-2060. DOI: 10.1016/S0040-4039(97)00284-0  0.377
1992 Schultz AG, Taveras AG, Taylor RE, Tham FS, Kullnig RK. Solid-state photochemistry. Remarkable effects of the packing of molecules in crystals on the diastereoselectivity of the intramolecular 2 + 2 photocycloaddition of a 4- (3′-butenyl)-2,5-cyclohexadien-1-one Journal of the American Chemical Society. 114: 8725-8727. DOI: 10.1021/Ja00048A070  0.504
1992 Schultz AG, Taylor RE. Diastereoselective ester enolate alkylations. Asymmetric syntheses of 3-alkyl-3-carbomethoxy-2-exo-methylene-5-cyclohexen-1-ones. [Erratum to document cited in CA116(21):214030x] Journal of the American Chemical Society. 114: 8341-8341. DOI: 10.1021/Ja00047A084  0.544
1992 Schultz AG, Taylor RE. Diastereoselective ester enolate alkylations. Asymmetric syntheses of 3-alkyl-3-carbomethoxy-2-exo-methylenecyclohex-5-en-1-ones Journal of the American Chemical Society. 114: 3937-3943. DOI: 10.1021/Ja00036A047  0.552
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