Christine Milcarek - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ghobrial A, Flick N, Daly R, Hoffman M, Milcarek C. ELL2 Influences Transcription Elongation, Splicing, Ig Secretion and Growth. Journal of Mucosal Immunology Research. 3. PMID 31930204  0.386
2018 Carew NT, Nelson AM, Liang Z, Smith SM, Milcarek C. Linking Endoplasmic Reticular Stress and Alternative Splicing. International Journal of Molecular Sciences. 19. PMID 30544499 DOI: 10.3390/Ijms19123919  0.531
2018 Nelson AM, Carew NT, Smith SM, Milcarek C. RNA Splicing in the Transition from B Cells to Antibody-Secreting Cells: The Influences of ELL2, Small Nuclear RNA, and Endoplasmic Reticulum Stress. Journal of Immunology (Baltimore, Md. : 1950). PMID 30297340 DOI: 10.4049/Jimmunol.1800557  0.533
2014 Bayles I, Milcarek C. Plasma cell formation, secretion, and persistence: the short and the long of it. Critical Reviews in Immunology. 34: 481-99. PMID 25597311 DOI: 10.1615/Critrevimmunol.2014012168  0.472
2014 Park KS, Bayles I, Szlachta-McGinn A, Paul J, Boiko J, Santos P, Liu J, Wang Z, Borghesi L, Milcarek C. Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response. Journal of Immunology (Baltimore, Md. : 1950). 193: 4663-74. PMID 25238757 DOI: 10.4049/Jimmunol.1401608  0.555
2013 Zhang L, Vlad A, Milcarek C, Finn OJ. Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms. Cancer Immunology, Immunotherapy : Cii. 62: 423-35. PMID 22941036 DOI: 10.1007/S00262-012-1325-2  0.408
2013 Arumemi F, Bayles I, Paul J, Milcarek C. Shared and discrete interacting partners of ELL1 and ELL2 by yeast two-hybrid assay Advances in Bioscience and Biotechnology. 4: 774-780. DOI: 10.4236/Abb.2013.47101  0.477
2011 Milcarek C, Albring M, Langer C, Park KS. The eleven-nineteen lysine-rich leukemia gene (ELL2) influences the histone H3 protein modifications accompanying the shift to secretory immunoglobulin heavy chain mRNA production. The Journal of Biological Chemistry. 286: 33795-803. PMID 21832080 DOI: 10.1074/Jbc.M111.272096  0.56
2011 Santos P, Arumemi F, Park KS, Borghesi L, Milcarek C. Transcriptional and epigenetic regulation of B cell development. Immunologic Research. 50: 105-12. PMID 21717070 DOI: 10.1007/S12026-011-8225-Y  0.46
2011 Kardava L, Yang Q, St Leger A, Foon KA, Lentzsch S, Vallejo AN, Milcarek C, Borghesi L. The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells. International Immunology. 23: 375-84. PMID 21551245 DOI: 10.1093/Intimm/Dxr027  0.425
2011 Hockert KJ, Martincic K, Mendis-Handagama SM, Borghesi LA, Milcarek C, Dass B, MacDonald CC. Spermatogenetic but not immunological defects in mice lacking the τCstF-64 polyadenylation protein. Journal of Reproductive Immunology. 89: 26-37. PMID 21489638 DOI: 10.1016/J.Jri.2011.01.018  0.361
2009 Martincic K, Alkan SA, Cheatle A, Borghesi L, Milcarek C. Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing. Nature Immunology. 10: 1102-9. PMID 19749764 DOI: 10.1038/Ni.1786  0.531
2009 Pal R, Janz M, Galson DL, Gries M, Li S, Jöhrens K, Anagnostopoulos I, Dörken B, Mapara MY, Borghesi L, Kardava L, Roodman GD, Milcarek C, Lentzsch S. C/EBPbeta regulates transcription factors critical for proliferation and survival of multiple myeloma cells. Blood. 114: 3890-8. PMID 19717648 DOI: 10.1182/Blood-2009-01-201111  0.408
2009 Price PW, McKinney EC, Wang Y, Sasser LE, Kandasamy MK, Matsuuchi L, Milcarek C, Deal RB, Culver DG, Meagher RB. Engineered cell surface expression of membrane immunoglobulin as a means to identify monoclonal antibody-secreting hybridomas. Journal of Immunological Methods. 343: 28-41. PMID 19187782 DOI: 10.1016/J.Jim.2009.01.005  0.384
2008 Yang Q, Kardava L, St Leger A, Martincic K, Varnum-Finney B, Bernstein ID, Milcarek C, Borghesi L. E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors. Journal of Immunology (Baltimore, Md. : 1950). 181: 5885-94. PMID 18941177 DOI: 10.4049/Jimmunol.181.9.5885  0.329
2007 Shell SA, Martincic K, Tran J, Milcarek C. Increased phosphorylation of the carboxyl-terminal domain of RNA polymerase II and loading of polyadenylation and cotranscriptional factors contribute to regulation of the ig heavy chain mRNA in plasma cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 7663-73. PMID 18025212 DOI: 10.4049/Jimmunol.179.11.7663  0.668
2006 Borghesi L, Milcarek C. From B cell to plasma cell: regulation of V(D)J recombination and antibody secretion. Immunologic Research. 36: 27-32. PMID 17337763 DOI: 10.1385/Ir:36:1:27  0.462
2006 Alkan SA, Martincic K, Milcarek C. The hnRNPs F and H2 bind to similar sequences to influence gene expression. The Biochemical Journal. 393: 361-71. PMID 16171461 DOI: 10.1042/Bj20050538  0.4
2005 Shell SA, Hesse C, Morris SM, Milcarek C. Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection. The Journal of Biological Chemistry. 280: 39950-61. PMID 16207706 DOI: 10.1074/Jbc.M508848200  0.639
2003 Milcarek C, Martincic K, Chung-Ganster LH, Lutz CS. The snRNP-associated U1A levels change following IL-6 stimulation of human B-cells. Molecular Immunology. 39: 809-14. PMID 12617996 DOI: 10.1016/S0161-5890(02)00263-8  0.493
2002 Arhin GK, Boots M, Bagga PS, Milcarek C, Wilusz J. Downstream sequence elements with different affinities for the hnRNP H/H' protein influence the processing efficiency of mammalian polyadenylation signals. Nucleic Acids Research. 30: 1842-50. PMID 11937639 DOI: 10.1093/Nar/30.8.1842  0.332
2001 Veraldi KL, Arhin GK, Martincic K, Chung-Ganster LH, Wilusz J, Milcarek C. hnRNP F influences binding of a 64-kilodalton subunit of cleavage stimulation factor to mRNA precursors in mouse B cells Molecular and Cellular Biology. 21: 1228-1238. PMID 11158309 DOI: 10.1128/Mcb.21.4.1228-1238.2001  0.476
2000 Veraldi KL, Edwalds-Gilbert G, MacDonald CC, Wallace AM, Milcarek C. Isolation and characterization of polyadenylation complexes assembled in vitro. Rna (New York, N.Y.). 6: 768-77. PMID 10836797 DOI: 10.1017/S135583820099246X  0.405
1999 Terhune SS, Milcarek C, Laimins LA. Regulation of human papillomavirus type 31 polyadenylation during the differentiation-dependent life cycle. Journal of Virology. 73: 7185-92. PMID 10438805 DOI: 10.1128/Jvi.73.9.7185-7192.1999  0.396
1998 Martincic K, Campbell R, Edwalds-Gilbert G, Souan L, Lotze MT, Milcarek C. Increase in the 64-kDa subunit of the polyadenylation/cleavage stimulatory factor during the G0 to S phase transition. Proceedings of the National Academy of Sciences of the United States of America. 95: 11095-100. PMID 9736695 DOI: 10.1073/Pnas.95.19.11095  0.48
1997 Hastings ML, Milcarek C, Martincic K, Peterson ML, Munroe SH. Expression of the thyroid hormone receptor gene, erbAalpha, in B lymphocytes: alternative mRNA processing is independent of differentiation but correlates with antisense RNA levels. Nucleic Acids Research. 25: 4296-300. PMID 9336460 DOI: 10.1093/Nar/25.21.4296  0.404
1997 Edwalds-Gilbert G, Veraldi KL, Milcarek C. Alternative poly(A) site selection in complex transcription units: means to an end? Nucleic Acids Research. 25: 2547-61. PMID 9185563 DOI: 10.1093/Nar/25.13.2547  0.544
1997 Matis SA, Martincic K, Milcarek C. B-lineage regulated polyadenylation occurs on weak poly(A) sites regardless of sequence composition at the cleavage and downstream regions. Nucleic Acids Research. 24: 4684-92. PMID 8972854 DOI: 10.1093/Nar/24.23.4684  0.427
1996 Milcarek C, Suda-Hartman M, Croll SC. Changes in abundance of IgG 2a mRNA in the nucleus and cytoplasm of a murine B-lymphoma before and after fusion to a myeloma cell. Molecular Immunology. 33: 691-701. PMID 8760281 DOI: 10.1016/0161-5890(96)00009-0  0.458
1995 Flaspohler JA, Boczkowski D, Hall BL, Milcarek C. The 3′-untranslated region of membrane exon 2 from the γ2a immunoglobulin gene contributes to efficient transcription termination Journal of Biological Chemistry. 270: 11903-11911. PMID 7744841 DOI: 10.1074/Jbc.270.20.11903  0.447
1995 Edwalds-Gilbert G, Milcarek C. Regulation of poly(A) site use during mouse B-cell development involves a change in the binding of a general polyadenylation factor in a B-cell stage-specific manner. Molecular and Cellular Biology. 15: 6420-9. PMID 7565794 DOI: 10.1128/Mcb.15.11.6420  0.459
1991 Genovese C, Harrold S, Milcarek C. Differential mRNA stabilities affect mRNA levels in mutant mouse myeloma cells. Somatic Cell and Molecular Genetics. 17: 69-81. PMID 1900133 DOI: 10.1007/Bf01233206  0.455
1991 Harrold S, Genovese C, Kobrin B, Morrison SL, Milcarek C. A comparison of apparent mRNA half-life using kinetic labeling techniques vs decay following administration of transcriptional inhibitors. Analytical Biochemistry. 198: 19-29. PMID 1789423 DOI: 10.1016/0003-2697(91)90500-S  0.417
1990 Hall B, Milcarek C. Sequence and polyadenylation site determination of the murine immunoglobulin gamma 2a membrane 3' untranslated region. Molecular Immunology. 26: 819-26. PMID 2513486 DOI: 10.1016/0161-5890(89)90137-5  0.316
1990 Genovese C, Milcarek C. Increased half-life of μ immunoglobulin mRNA during mouse B cell development increases its abundancy Molecular Immunology. 27: 733-743. PMID 2119479 DOI: 10.1016/0161-5890(90)90082-B  0.523
1988 Kobrin B, Glass K, Morrison SL, Milcarek C. An immunoglobulin heavy chain gene deletion at direct repeats: Nucleotide sequence and effect on mrna accumulation Molecular Immunology. 25: 181-187. PMID 3131666 DOI: 10.1016/0161-5890(88)90066-1  0.413
1986 Milcarek C, Hall B. Cell-specific expression of secreted versus membrane forms of immunoglobulin gamma 2b mRNA involves selective use of alternate polyadenylation sites. Molecular and Cellular Biology. 5: 2514-20. PMID 3939252 DOI: 10.1128/MCB.5.10.2514  0.416
1986 Gregor PD, Kobrin BJ, Milcarek C, Morrison SL. Sequences 3' of immunoglobulin heavy chain genes influence their expression Immunological Reviews. 89: 31-48. PMID 3081431 DOI: 10.1111/J.1600-065X.1986.Tb01471.X  0.517
1986 Kobrin BJ, Milcarek C, Morrison SL. Sequences near the 3' secretion-specific polyadenylation site influence levels of secretion-specific and membrane specific IgG2b mRNA in myeloma cells Molecular and Cellular Biology. 6: 1687-1697. PMID 2878362 DOI: 10.1128/Mcb.6.5.1687  0.526
1981 Monk RJ, Morrison SL, Milcarek C. Heavy-chain mutants derived from γ2b mouse myeloma: Characterization of heavy-chain messenger ribonucleic acid, proteins, and secretion in deletion mutants and messenger ribonucleic acid in γ2a mutant progeny Biochemistry. 20: 2330-2339. PMID 6263311 DOI: 10.1021/Bi00511A040  0.421
1980 Milcarek C. HeLa cell cytoplasmic mRNA contains three classes of sequences: predominantly poly(A)-free, predominantly poly(A)-containing and bimorphic. European Journal of Biochemistry. 102: 467-76. PMID 527589 DOI: 10.1111/j.1432-1033.1979.tb04261.x  0.333
1977 Kaufmann Y, Milcarek C, Berissi H, Penman S. HeLa cell poly(A)- mRNA codes for a subset of poly(A)+ mRNA-directed proteins with an actin as a major product. Proceedings of the National Academy of Sciences of the United States of America. 74: 4801-5. PMID 270712 DOI: 10.1073/Pnas.74.11.4801  0.408
1974 Milcarek C, Price R, Penman S. The metabolism of a poly(A) minus mRNA fraction in HeLa cells. Cell. 3: 1-10. PMID 4213457 DOI: 10.1016/0092-8674(74)90030-0  0.32
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