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Hestia S. Mellert, Ph.D. - Publications

Affiliations: 
2011 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Oran AR, Adams CM, Zhang XY, Gennaro VJ, Pfeiffer HK, Mellert HS, Seidel HE, Mascioli K, Kaplan J, Gaballa MR, Shen C, Rigoutsos I, King MP, Cotney JL, Arnold JJ, et al. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer. Oncotarget. PMID 27590350 DOI: 10.18632/Oncotarget.11718  0.629
2016 Monteith JA, Mellert H, Sammons MA, Kuswanto LA, Sykes SM, Resnick-Silverman L, Manfredi JJ, Berger SL, McMahon SB. A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction. Molecular Oncology. PMID 27341992 DOI: 10.1016/J.Molonc.2016.05.007  0.72
2014 Thangavel C, Boopathi E, Ciment S, Liu Y, O' Neill R, Sharma A, McMahon SB, Mellert H, Addya S, Ertel A, Birbe R, Fortina P, Dicker AP, Knudsen KE, Den RB. The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5468-82. PMID 25165096 DOI: 10.1158/1078-0432.Ccr-14-0326  0.303
2014 Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA, Sullivan KD, Galbraith MD, Luo X, Kraus WL, Dowell RD, Espinosa JM. Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. Elife. 3: e02200. PMID 24867637 DOI: 10.7554/Elife.02200  0.402
2013 Mellert H, Espinosa JM. Tumor suppression by p53: is apoptosis important or not? Cell Reports. 3: 1335-6. PMID 23726020 DOI: 10.1016/j.celrep.2013.05.011  0.323
2012 Den RB, Ciment S, Sharma A, Mellert H, McMahon S, Dicker A, Knudsen KE. Differential response of prostate cancer cells to ionizing radiation: The RB status. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 106. PMID 27968000 DOI: 10.1200/Jco.2012.30.5_Suppl.106  0.593
2012 Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, et al. MYST protein acetyltransferase activity requires active site lysine autoacetylation. The Embo Journal. 31: 58-70. PMID 22020126 DOI: 10.1038/Emboj.2011.382  0.61
2011 Den RB, Ciment S, Sharma A, Mellert H, Mc-Mahon S, Dicker A, Knudsen KE. Relationship between the loss of the retinoblastoma tumor suppressor and radiosensitivity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 34. PMID 27968373 DOI: 10.1200/Jco.2011.29.7_Suppl.34  0.319
2011 Zhang XY, Pfeiffer HK, Mellert HS, Stanek TJ, Sussman RT, Kumari A, Yu D, Rigoutsos I, Thomas-Tikhonenko A, Seidel HE, Chodosh LA, Packham G, Baserga R, McMahon SB. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC. Molecular and Cellular Biology. 31: 5037-45. PMID 21986497 DOI: 10.1128/Mcb.06297-11  0.651
2011 Charvet C, Wissler M, Brauns-Schubert P, Wang SJ, Tang Y, Sigloch FC, Mellert H, Brandenburg M, Lindner SE, Breit B, Green DR, McMahon SB, Borner C, Gu W, Maurer U. Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Molecular Cell. 42: 584-96. PMID 21658600 DOI: 10.1016/J.Molcel.2011.03.033  0.689
2011 Mellert HS, Stanek TJ, Sykes SM, Rauscher FJ, Schultz DC, McMahon SB. Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis. The Journal of Biological Chemistry. 286: 4264-70. PMID 21148320 DOI: 10.1074/Jbc.M110.184663  0.748
2011 La Rocca G, Shi B, Audia A, Ferrari-Amorotti G, Mellert HS, Calabretta B, McMahon SB, Sepp-Lorenzino L, Baserga R. Regulation of microRNA-145 by growth arrest and differentiation. Experimental Cell Research. 317: 488-95. PMID 21111732 DOI: 10.1016/J.Yexcr.2010.11.010  0.572
2010 Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, Diehl JA. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell. 18: 329-40. PMID 20951943 DOI: 10.1016/J.Ccr.2010.08.012  0.617
2009 Mellert HS, McMahon SB. hMOF, a KAT(8) with many lives. Molecular Cell. 36: 174-5. PMID 19854127 DOI: 10.1016/J.Molcel.2009.10.005  0.581
2009 Mellert HS, McMahon SB. Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells. Trends in Biochemical Sciences. 34: 571-8. PMID 19819149 DOI: 10.1016/J.Tibs.2009.06.010  0.64
2007 Mellert H, Sykes SM, Murphy ME, McMahon SB. The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain. Cell Cycle (Georgetown, Tex.). 6: 1304-6. PMID 17534149 DOI: 10.4161/Cc.6.11.4343  0.725
2006 Sykes SM, Mellert HS, Holbert MA, Li K, Marmorstein R, Lane WS, McMahon SB. Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Molecular Cell. 24: 841-51. PMID 17189187 DOI: 10.1016/J.Molcel.2006.11.026  0.736
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