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Jiaxin Hu - Publications

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Johnson KC, Kilikevicius A, Hofman C, Hu J, Liu Y, Aguilar S, Graswich J, Han Y, Wang T, Westcott JM, Brekken RA, Peng L, Karagkounis G, Corey DR. Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs. Nucleic Acids Research. PMID 38109320 DOI: 10.1093/nar/gkad1155  0.495
2023 Hu J, Shen X, Kheirabadi M, Streeter MD, Qian Z, Mootha VV, Corey DR. Targeting the Expanded /Fuchs' Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates. Acs Omega. 8: 42797-42802. PMID 38024683 DOI: 10.1021/acsomega.3c05634  0.588
2023 Hu J, Gong X, Fan Y, Aguilar S, Rigo F, Prakash TP, Corey DR, Mootha VV. Modulation of Gene Expression in the Eye with Antisense Oligonucleotides. Nucleic Acid Therapeutics. PMID 37917066 DOI: 10.1089/nat.2023.0044  0.506
2023 Cao S, Zhu H, Cui J, Liu S, Li Y, Shi J, Mo J, Wang Z, Wang H, Hu J, Chen L, Li Y, Xia L, Xiao S. Allele-specific RNA -methyladenosine modifications reveal functional genetic variants in human tissues. Genome Research. 33: 1369-1380. PMID 37714712 DOI: 10.1101/gr.277704.123  0.323
2023 Johnson KC, Kilikevicius A, Hofman C, Hu J, Liu Y, Aguilar S, Graswich J, Han Y, Wang T, Westcott JM, Brekken RA, Peng L, Karagkounis G, Corey DR. Nuclear Localization of Argonaute is affected by Cell Density and May Relieve Repression by microRNAs. Biorxiv : the Preprint Server For Biology. PMID 37461596 DOI: 10.1101/2023.07.07.548119  0.495
2023 Hu J, Gong X, Johnson ST, Corey DR, Mootha VV. The TCF4 Trinucleotide Repeat Expansion of Fuchs' Endothelial Corneal Dystrophy: Implications for the Anterior Segment of the Eye. Investigative Ophthalmology & Visual Science. 64: 16. PMID 37204786 DOI: 10.1167/iovs.64.5.16  0.57
2020 Chu Y, Hu J, Liang H, Kanchwala M, Xing C, Beebe W, Bowman CB, Gong X, Corey DR, Mootha VV. Analyzing pre-symptomatic tissue to gain insights into the molecular and mechanistic origins of late-onset degenerative trinucleotide repeat disease. Nucleic Acids Research. PMID 32463444 DOI: 10.1093/Nar/Gkaa422  0.66
2020 Chau VQ, Hu J, Gong X, Hulleman JD, Ufret-Vincenty RL, Rigo F, Prakash TP, Corey DR, Mootha VV. Delivery of Antisense Oligonucleotides to the Cornea. Nucleic Acid Therapeutics. PMID 32202944 DOI: 10.1089/Nat.2019.0838  0.659
2019 Hu J, Corey DR. Limits of using oligonucleotides for allele-selective inhibition at trinucleotide repeat sequences - targeting the CAG repeat within ataxin-1. Nucleosides, Nucleotides & Nucleic Acids. 1-10. PMID 31645175 DOI: 10.1080/15257770.2019.1671592  0.67
2019 Rong Z, Hu J, Corey DR, Mootha VV. Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy. Investigative Ophthalmology & Visual Science. 60: 3980-3991. PMID 31560764 DOI: 10.1167/Iovs.19-27641  0.682
2019 Hu J, Shen X, Rigo F, Prakash TP, Mootha VV, Corey DR. Duplex RNAs and ss-siRNAs Block RNA Foci Associated with Fuchs' Endothelial Corneal Dystrophy. Nucleic Acid Therapeutics. PMID 30676271 DOI: 10.1089/Nat.2018.0764  0.704
2018 Hu J, Rong Z, Gong X, Zhou Z, Sharma VK, Xing C, Watts JK, Corey DR, Mootha VV. Oligonucleotides Targeting TCF4 Triplet Repeat Expansion Inhibit RNA Foci and Mis-splicing in Fuchs' Dystrophy. Human Molecular Genetics. PMID 29325021 DOI: 10.1093/Hmg/Ddy018  0.71
2017 Liu J, Hu J, Ludlow AT, Pham JT, Shay JW, Rothstein JD, Corey DR. c9orf72 Disease-Related Foci Are Each Composed of One Mutant Expanded Repeat RNA. Cell Chemical Biology. PMID 28132891 DOI: 10.1016/J.Chembiol.2016.12.018  0.675
2016 Hu J, Rigo F, Prakash TP, Corey DR. Recognition of c9orf72 Mutant RNA by Single-Stranded Silencing RNAs. Nucleic Acid Therapeutics. PMID 28005462 DOI: 10.1089/nat.2016.0655  0.698
2015 Hu J, Liu J, Li L, Gagnon KT, Corey DR. Engineering Duplex RNAs for Challenging Targets: Recognition of GGGGCC/CCCCGG Repeats at the ALS/FTD C9orf72 Locus. Chemistry & Biology. PMID 26584779 DOI: 10.1016/J.Chembiol.2015.09.016  0.699
2015 Liu J, Hu J, Hicks JA, Prakash TP, Corey DR. Modulation of Splicing by Single-Stranded Silencing RNAs. Nucleic Acid Therapeutics. 25: 113-20. PMID 25757055 DOI: 10.1089/Nat.2014.0527  0.713
2014 Hu J, Liu J, Narayanannair KJ, Lackey JG, Kuchimanchi S, Rajeev KG, Manoharan M, Swayze EE, Lima WF, Prakash TP, Xiang Q, Martinez C, Corey DR. Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs. Biochemistry. 53: 4510-8. PMID 24981774 DOI: 10.1021/Bi500610R  0.731
2014 Hu J, Liu J, Yu D, Aiba Y, Lee S, Pendergraff H, Boubaker J, Artates JW, Lagier-Tourenne C, Lima WF, Swayze EE, Prakash TP, Corey DR. Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs. Nucleic Acid Therapeutics. 24: 199-209. PMID 24694346 DOI: 10.1089/Nat.2013.0476  0.721
2013 Aiba Y, Hu J, Liu J, Xiang Q, Martinez C, Corey DR. Allele-selective inhibition of expression of huntingtin and ataxin-3 by RNA duplexes containing unlocked nucleic acid substitutions. Biochemistry. 52: 9329-38. PMID 24266403 DOI: 10.1021/Bi4014209  0.711
2013 Liu J, Yu D, Aiba Y, Pendergraff H, Swayze EE, Lima WF, Hu J, Prakash TP, Corey DR. ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy. Nucleic Acids Research. 41: 9570-83. PMID 23935115 DOI: 10.1093/Nar/Gkt693  0.727
2013 Liu J, Pendergraff H, Narayanannair KJ, Lackey JG, Kuchimanchi S, Rajeev KG, Manoharan M, Hu J, Corey DR. RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression. Nucleic Acids Research. 41: 8788-801. PMID 23887934 DOI: 10.1093/Nar/Gkt594  0.737
2012 Hu J, Liu J, Yu D, Chu Y, Corey DR. Mechanism of allele-selective inhibition of huntingtin expression by duplex RNAs that target CAG repeats: function through the RNAi pathway. Nucleic Acids Research. 40: 11270-80. PMID 23042244 DOI: 10.1093/Nar/Gks907  0.717
2012 Liu J, Hu J, Corey DR. Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing. Nucleic Acids Research. 40: 1240-50. PMID 21948593 DOI: 10.1093/Nar/Gkr780  0.706
2011 Hu J, Gagnon KT, Liu J, Watts JK, Syeda-Nawaz J, Bennett CF, Swayze EE, Randolph J, Chattopadhyaya J, Corey DR. Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs. Biological Chemistry. 392: 315-25. PMID 21294677 DOI: 10.1515/Bc.2011.045  0.699
2010 Hu J, Liu J, Corey DR. Allele-selective inhibition of huntingtin expression by switching to an miRNA-like RNAi mechanism. Chemistry & Biology. 17: 1183-8. PMID 21095568 DOI: 10.1016/J.Chembiol.2010.10.013  0.703
2010 Wancewicz EV, Maier MA, Siwkowski AM, Albertshofer K, Winger TM, Berdeja A, Gaus H, Vickers TA, Bennett CF, Monia BP, Griffey RH, Nulf CJ, Hu J, Corey DR, Swayze EE, et al. Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue. Journal of Medicinal Chemistry. 53: 3919-26. PMID 20420385 DOI: 10.1021/Jm901489K  0.551
2009 Hu J, Matsui M, Corey DR. Allele-selective inhibition of mutant huntingtin by peptide nucleic acid-peptide conjugates, locked nucleic acid, and small interfering RNA. Annals of the New York Academy of Sciences. 1175: 24-31. PMID 19796074 DOI: 10.1111/J.1749-6632.2009.04975.X  0.7
2009 Hu J, Dodd DW, Hudson RH, Corey DR. Cellular localization and allele-selective inhibition of mutant huntingtin protein by peptide nucleic acid oligomers containing the fluorescent nucleobase [bis-o-(aminoethoxy)phenyl]pyrrolocytosine. Bioorganic & Medicinal Chemistry Letters. 19: 6181-4. PMID 19783436 DOI: 10.1016/J.Bmcl.2009.09.004  0.629
2009 Hu J, Matsui M, Gagnon KT, Schwartz JC, Gabillet S, Arar K, Wu J, Bezprozvanny I, Corey DR. Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs. Nature Biotechnology. 27: 478-84. PMID 19412185 DOI: 10.1038/Nbt.1539  0.698
2007 Hu J, Corey DR. Inhibiting gene expression with peptide nucleic acid (PNA)--peptide conjugates that target chromosomal DNA. Biochemistry. 46: 7581-9. PMID 17536840 DOI: 10.1021/Bi700230A  0.596
2006 Janowski BA, Hu J, Corey DR. Silencing gene expression by targeting chromosomal DNA with antigene peptide nucleic acids and duplex RNAs. Nature Protocols. 1: 436-43. PMID 17406266 DOI: 10.1038/Nprot.2006.64  0.67
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