Year |
Citation |
Score |
2023 |
Hu J, Shen X, Kheirabadi M, Streeter MD, Qian Z, Mootha VV, Corey DR. Targeting the Expanded /Fuchs' Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates. Acs Omega. 8: 42797-42802. PMID 38024683 DOI: 10.1021/acsomega.3c05634 |
0.403 |
|
2023 |
Li X, Kheirabadi M, Dougherty PG, Kamer KJ, Shen X, Estrella NL, Peddigari S, Pathak A, Blake SL, Sizensky E, Genio CD, Gaur AB, Dhanabal M, Girgenrath M, Sethuraman N, ... Qian Z, et al. The endosomal escape vehicle platform enhances delivery of oligonucleotides in preclinical models of neuromuscular disorders. Molecular Therapy. Nucleic Acids. 33: 273-285. PMID 37538053 DOI: 10.1016/j.omtn.2023.06.022 |
0.393 |
|
2020 |
Dougherty PG, Karpurapu M, Koley A, Lukowski JK, Qian Z, Srinivas Nirujogi T, Rusu L, Chung S, Hummon AB, Li HW, Christman JW, Pei D. A Peptidyl Inhibitor that Blocks Calcineurin-NFAT Interaction and Prevents Acute Lung Injury. Journal of Medicinal Chemistry. PMID 33073986 DOI: 10.1021/acs.jmedchem.0c01236 |
0.42 |
|
2020 |
Wen J, Liao H, Stachowski K, Hempfling JP, Qian Z, Yuan C, Foster MP, Pei D. Rational design of cell-permeable cyclic peptides containing a d-Pro-l-Pro motif. Bioorganic & Medicinal Chemistry. 28: 115711. PMID 33069067 DOI: 10.1016/J.Bmc.2020.115711 |
0.649 |
|
2020 |
Sahni A, Qian Z, Pei D. Cell-Penetrating Peptides Escape the Endosome by Inducing Vesicle Budding and Collapse. Acs Chemical Biology. PMID 32786250 DOI: 10.1021/Acschembio.0C00478 |
0.689 |
|
2019 |
Dougherty PG, Wen J, Pan X, Koley A, Ren JG, Sahni A, Basu R, Salim H, Appiah-Kubi G, Qian Z, Pei D. Enhancing the Cell-Permeability of Stapled Peptides with a Cyclic Cell-Penetrating Peptide. Journal of Medicinal Chemistry. PMID 31657556 DOI: 10.1021/Acs.Jmedchem.9B00456 |
0.724 |
|
2019 |
Pei D, Song J, Qian Z, Sahni A, Chen K. Cyclic Cell-Penetrating Peptides with Single Hydrophobic Groups. Chembiochem : a European Journal of Chemical Biology. PMID 31298779 DOI: 10.1002/Cbic.201900370 |
0.66 |
|
2018 |
Pei D, Appiah Kubi G, Qian Z, Amiar S, Sahni A, Stahelin RV. Non-Peptidic Cell-Penetrating Motifs for Mitochondrion-Specific Cargo Delivery. Angewandte Chemie (International Ed. in English). PMID 30376611 DOI: 10.1002/Anie.201811940 |
0.614 |
|
2018 |
Rhodes CA, Dougherty PG, Cooper JK, Qian Z, Lindert S, Wang QE, Pei D. Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB kinase Interaction Directly from a Combinatorial Library. Journal of the American Chemical Society. PMID 30176143 DOI: 10.1021/Jacs.8B06738 |
0.675 |
|
2018 |
Karpurapu M, Lee YG, Qian Z, Wen J, Ballinger MN, Rusu L, Chung S, Deng J, Qian F, Reader BF, Nirujogi TS, Park GY, Pei D, Christman JW. Inhibition of nuclear factor of activated T cells (NFAT) c3 activation attenuates acute lung injury and pulmonary edema in murine models of sepsis. Oncotarget. 9: 10606-10620. PMID 29535830 DOI: 10.18632/Oncotarget.24320 |
0.483 |
|
2017 |
Qian Z, Dougherty PG, Pei D. Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides. Current Opinion in Chemical Biology. 38: 80-86. PMID 28388463 DOI: 10.1016/J.Cbpa.2017.03.011 |
0.721 |
|
2017 |
Dougherty PG, Qian Z, Pei D. Macrocycles as protein-protein interaction inhibitors. The Biochemical Journal. 474: 1109-1125. PMID 28298556 DOI: 10.1042/Bcj20160619 |
0.614 |
|
2016 |
Qian Z, Rhodes CA, McCroskey LC, Wen J, Appiah-Kubi G, Wang DJ, Guttridge DC, Pei D. Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization. Angewandte Chemie (International Ed. in English). PMID 28035784 DOI: 10.1002/Anie.201610888 |
0.682 |
|
2016 |
Qian Z, Martyna A, Hard RL, Wang J, Appiah-Kubi G, Coss CC, Phelps M, Rossman JS, Pei D. Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides. Biochemistry. PMID 27089101 DOI: 10.1021/Acs.Biochem.6B00226 |
0.759 |
|
2015 |
Trinh TB, Upadhyaya P, Qian Z, Pei D. Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides. Acs Combinatorial Science. PMID 26645887 DOI: 10.1021/Acscombsci.5B00164 |
0.817 |
|
2015 |
Upadhyaya P, Qian Z, Selner NG, Clippinger SR, Wu Z, Briesewitz R, Pei D. Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides. Angewandte Chemie (International Ed. in English). 54: 7602-6. PMID 25950772 DOI: 10.1002/Anie.201502763 |
0.722 |
|
2015 |
Qian Z, Xu X, Amacher JF, Madden DR, Cormet-Boyaka E, Pei D. Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity. Angewandte Chemie (International Ed. in English). 54: 5874-8. PMID 25785567 DOI: 10.1002/Anie.201411594 |
0.709 |
|
2015 |
Qian Z, Upadhyaya P, Pei D. Synthesis and screening of one-bead-one-compound cyclic peptide libraries. Methods in Molecular Biology (Clifton, N.J.). 1248: 39-53. PMID 25616324 DOI: 10.1007/978-1-4939-2020-4_3 |
0.76 |
|
2015 |
Qian Z, Dougherty PG, Pei D. Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore. Chemical Communications (Cambridge, England). 51: 2162-5. PMID 25554998 DOI: 10.1039/C4Cc09441G |
0.638 |
|
2014 |
Upadhyaya P, Qian Z, Habir NA, Pei D. Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library. Tetrahedron. 70: 7714-7720. PMID 25284901 DOI: 10.1016/J.Tet.2014.05.113 |
0.741 |
|
2014 |
Qian Z, Dougherty PG, Liu T, Oottikkal S, Hogan PG, Hadad CM, Pei D. Structure-based optimization of a peptidyl inhibitor against calcineurin-nuclear factor of activated T cell (NFAT) interaction. Journal of Medicinal Chemistry. 57: 7792-7. PMID 25162754 DOI: 10.1021/Jm500743T |
0.598 |
|
2014 |
Lian W, Jiang B, Qian Z, Pei D. Cell-permeable bicyclic peptide inhibitors against intracellular proteins. Journal of the American Chemical Society. 136: 9830-3. PMID 24972263 DOI: 10.1021/Ja503710N |
0.815 |
|
2014 |
Qian Z, LaRochelle JR, Jiang B, Lian W, Hard RL, Selner NG, Luechapanichkul R, Barrios AM, Pei D. Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery. Biochemistry. 53: 4034-46. PMID 24896852 DOI: 10.1021/Bi5004102 |
0.586 |
|
2013 |
Qian Z, Liu T, Liu YY, Briesewitz R, Barrios AM, Jhiang SM, Pei D. Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs. Acs Chemical Biology. 8: 423-31. PMID 23130658 DOI: 10.1021/Cb3005275 |
0.746 |
|
2012 |
Dewan V, Liu T, Chen KM, Qian Z, Xiao Y, Kleiman L, Mahasenan KV, Li C, Matsuo H, Pei D, Musier-Forsyth K. Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction. Acs Chemical Biology. 7: 761-9. PMID 22276994 DOI: 10.1021/Cb200450W |
0.639 |
|
2011 |
Liu T, Qian Z, Xiao Q, Pei D. High-throughput screening of one-bead-one-compound libraries: identification of cyclic peptidyl inhibitors against calcineurin/NFAT interaction. Acs Combinatorial Science. 13: 537-46. PMID 21848276 DOI: 10.1021/Co200101W |
0.655 |
|
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