| Year |
Citation |
Score |
| 2022 |
Jang H, Park Y, Jang J. Serum and glucocorticoid-regulated kinase 1: Structure, biological functions, and its inhibitors. Frontiers in Pharmacology. 13: 1036844. PMID 36457711 DOI: 10.3389/fphar.2022.1036844 |
0.4 |
|
| 2022 |
Beyett TS, To C, Heppner DE, Rana JK, Schmoker AM, Jang J, De Clercq DJH, Gomez G, Scott DA, Gray NS, Jänne PA, Eck MJ. Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors. Nature Communications. 13: 2530. PMID 35534503 DOI: 10.1038/s41467-022-30258-y |
0.585 |
|
| 2022 |
To C, Beyett TS, Jang J, Feng WW, Bahcall M, Haikala HM, Shin BH, Heppner DE, Rana JK, Leeper BA, Soroko KM, Poitras MJ, Gokhale PC, Kobayashi Y, Wahid K, et al. An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer. Nature Cancer. PMID 35422503 DOI: 10.1038/s43018-022-00351-8 |
0.613 |
|
| 2022 |
Gero TW, Heppner DE, Beyett TS, To C, Azevedo SC, Jang J, Bunnell T, Feru F, Li Z, Hee Shin B, Soroko KM, Gokhale PC, Gray NS, Jänne PA, Eck MJ, et al. Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC. Bioorganic & Medicinal Chemistry Letters. 128718. PMID 35378251 DOI: 10.1016/j.bmcl.2022.128718 |
0.577 |
|
| 2022 |
Son J, Jang J, Beyett TS, Eum Y, Haikala HM, Verano A, Lin M, Hatcher JM, Kwiatkowski NP, Eser PÖ, Poitras MJ, Wang S, Xu M, Gokhale PC, Cameron MD, et al. A novel HER2-selective kinase inhibitor is effective in HER2 mutant and amplified non-small cell lung cancer. Cancer Research. PMID 35149586 DOI: 10.1158/0008-5472.CAN-21-2693 |
0.759 |
|
| 2020 |
Jang J, To C, De Clercq DJH, Park E, Ponthier CM, Shin BH, Mushajiang M, Nowak RP, Fischer ES, Eck MJ, Jänne PA, Gray NS. Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations. Angewandte Chemie (International Ed. in English). PMID 32510788 DOI: 10.1002/Anie.202003500 |
0.64 |
|
| 2019 |
De Clercq DJH, Heppner DE, To C, Jang J, Park E, Yun CH, Mushajiang M, Shin BH, Gero TW, Scott DA, Jänne PA, Eck MJ, Gray NS. Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors. Acs Medicinal Chemistry Letters. 10: 1549-1553. PMID 31749909 DOI: 10.1021/Acsmedchemlett.9B00381 |
0.686 |
|
| 2019 |
Lian W, Jang J, Potisopon S, Li PC, Rahmeh A, Wang J, Kwiatkowski NP, Gray NS, Yang PL. Correction to Discovery of Immunologically Inspired Small Molecules That Target the Viral Envelope Protein. Acs Infectious Diseases. PMID 31675213 DOI: 10.1021/Acsinfecdis.9B00401 |
0.538 |
|
| 2019 |
To C, Jang J, Chen T, Park E, Mushajiang M, De Clercq DJH, Xu M, Wang S, Cameron MD, Heppner DE, Shin BH, Gero TW, Yang A, Dahlberg SE, Wong KK, et al. Single and dual targeting of mutant EGFR with an allosteric inhibitor. Cancer Discovery. PMID 31092401 DOI: 10.1158/2159-8290.Cd-18-0903 |
0.692 |
|
| 2019 |
Pitts J, Hsia CY, Lian W, Wang J, Pfeil MP, Kwiatkowski N, Li Z, Jang J, Gray NS, Yang PL. Identification of small molecule inhibitors targeting the Zika virus envelope protein. Antiviral Research. PMID 30771406 DOI: 10.1016/J.Antiviral.2019.02.008 |
0.533 |
|
| 2019 |
Li PC, Jang J, Hsia CY, Groomes P, Lian W, de Wispelaere M, Pitts JD, Wang J, Kwaitkowski N, Gray NS, Yang PL. Small molecules targeting the flavivirus E protein with broad-spectrum activity and antiviral efficacy in vivo. Acs Infectious Diseases. PMID 30608640 DOI: 10.1021/Acsinfecdis.8B00322 |
0.537 |
|
| 2018 |
Mah S, Jang J, Song D, Shin Y, Latif M, Jung Y, Hong S. Discovery of fluorescent 3-heteroarylcoumarin derivatives as novel inhibitors of anaplastic lymphoma kinase. Organic & Biomolecular Chemistry. PMID 30534706 DOI: 10.1039/C8Ob02874E |
0.363 |
|
| 2018 |
Lian W, Jang J, Potisopon S, Li PC, Rahmeh A, Wang J, Kwiatkowski NP, Gray NS, Yang PL. Discovery of Immunologically Inspired Small Molecules that Target the Viral Envelope Protein. Acs Infectious Diseases. PMID 30027735 DOI: 10.1021/Acsinfecdis.8B00127 |
0.547 |
|
| 2018 |
Chao LH, Jang J, Johnson A, Nguyen A, Gray N, Yang PL, Harrison SC. How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion. Elife. 7. PMID 29999491 DOI: 10.7554/Elife.36461 |
0.468 |
|
| 2018 |
Jang J, Son J, Park E, Kosaka T, Saxon JA, De Clercq D, Choi HG, Tanizaki J, Eck MJ, Jänne PA, Gray NS. Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor. Angewandte Chemie (International Ed. in English). PMID 29978938 DOI: 10.1002/Anie.201805187 |
0.668 |
|
| 2018 |
de Wispelaere M, Lian W, Potisopon S, Li PC, Jang J, Ficarro SB, Clark MJ, Zhu X, Kaplan JB, Pitts JD, Wales TE, Wang J, Engen JR, Marto JA, Gray NS, et al. Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein. Cell Chemical Biology. PMID 29937406 DOI: 10.1016/J.Chembiol.2018.05.011 |
0.552 |
|
| 2018 |
Chao LH, Jang J, Johnson A, Nguyen A, Gray NS, Yang PL, Harrison SC. Author response: How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion Elife. DOI: 10.7554/Elife.36461.014 |
0.342 |
|
| 2017 |
Huang HT, Dobrovolsky D, Paulk J, Yang G, Weisberg EL, Doctor ZM, Buckley DL, Cho JH, Ko E, Jang J, Shi K, Choi HG, Griffin JD, Li Y, Treon SP, et al. A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader. Cell Chemical Biology. PMID 29129717 DOI: 10.1016/J.Chembiol.2017.10.005 |
0.553 |
|
| 2017 |
Jang J, Son JB, To C, Bahcall M, Kim SY, Kang SY, Mushajiang M, Lee Y, Jänne PA, Choi HG, Gray NS. Discovery of a potent dual ALK and EGFR T790M inhibitor. European Journal of Medicinal Chemistry. 136: 497-510. PMID 28528303 DOI: 10.1016/J.Ejmech.2017.04.079 |
0.679 |
|
| 2016 |
Jia Y, Yun CH, Park E, Ercan D, Manuia M, Juarez J, Xu C, Rhee K, Chen T, Zhang H, Palakurthi S, Jang J, Lelais G, DiDonato M, Bursulaya B, et al. Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors. Nature. 534: 129-32. PMID 27251290 DOI: 10.1038/Nature17960 |
0.614 |
|
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