Kirk U. Knowlton - Publications

Affiliations: 
Biology (Joint Doctoral SDSU) University of California, San Diego, La Jolla, CA 
Area:
Virology Biology, Immunology, Molecular Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pandey AK, Lee NS, Marsal J, Knowlton KU, McDivit AM, Blanchard DG, Pretorius V, Madani MM, Fedullo PF, Kerr KM, Kim NH, Fernandes TM, Poch DS, Auger WR, Daniels LB. Evaluation of routine coronary angiography prior to pulmonary thromboendarterectomy. The Annals of Thoracic Surgery. PMID 32896544 DOI: 10.1016/J.Athoracsur.2020.06.107  0.3
2020 Zhang J, Vincent KP, Peter AK, Klos M, Cheng H, Huang SM, Towne JK, Ferng D, Gu Y, Dalton ND, Chan Y, Li R, Peterson KL, Chen J, McCulloch AD, ... Knowlton KU, et al. Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does not Alter Ventricular Function. Circulation Research. PMID 32345129 DOI: 10.1161/Circresaha.119.315539  0.337
2020 Muhlestein JB, Kammerer J, Bair T, Knowlton K, Le VT, Anderson JL, Lappe D, May HT. Incidence Of, And Overall Clinical Burden Associated With, Hyperkalemia In A Large Integrated Healthcare System Journal of the American College of Cardiology. 75: 1910. DOI: 10.1016/S0735-1097(20)32537-7  0.307
2020 Muhlestein JB, Kammerer J, Bair T, Knowlton K, Le VT, Anderson JL, Lappe D, May H. Effect Of Baseline Left Ventricular Ejection Fraction On Future Clinical Outcomes In A Real-World Population Of Patients With Heart Failure: How Exactly Does Hfref Compare With Hfpef? Journal of the American College of Cardiology. 75: 899. DOI: 10.1016/S0735-1097(20)31526-6  0.326
2019 Anderson JL, Le VT, Min DB, Biswas S, Minder CM, McCubrey RO, Knight S, Horne BD, Mason S, Lappe DL, Muhlestein JB, Knowlton KU. Comparison of Three Atherosclerotic Cardiovascular Disease Risk Scores With and Without Coronary Calcium for Predicting Revascularization and Major Adverse Coronary Events in Symptomatic Patients Undergoing Positron Emission Tomography-Stress Testing. The American Journal of Cardiology. PMID 31806210 DOI: 10.1016/J.Amjcard.2019.10.044  0.314
2019 Boralkar KA, Kobayashi Y, Amsallem M, Ataam JA, Moneghetti KJ, Cauwenberghs N, Horne BD, Knowlton KU, Maecker H, Kuznetsova T, Heidenreich PA, Haddad F. Value of Neutrophil to Lymphocyte Ratio and Its Trajectory in Patients Hospitalized With Acute Heart Failure and Preserved Ejection Fraction. The American Journal of Cardiology. PMID 31753313 DOI: 10.1016/J.Amjcard.2019.10.020  0.324
2019 Knowlton KU. Dilated Cardiomyopathy: Viral Persistence and a Role for a Viral Proteinase in Human Hearts Circulation. 139: 2339-2341. PMID 31082299 DOI: 10.1161/Circulationaha.119.040037  0.319
2019 Zhang Z, Mu Y, Zhang J, Zhou Y, Cattaneo P, Veevers J, Peter AK, Manso AM, Knowlton KU, Zhou X, Evans SM, Ross RS, Chen J. Kindlin-2 Is Essential for Preserving Integrity of the Developing Heart and Preventing Ventricular Rupture. Circulation. 139: 1554-1556. PMID 30883226 DOI: 10.1161/Circulationaha.118.038383  0.325
2019 Knight S, Bride D, Mason S, Le VT, Min D, Meredith KG, Biswas S, Anderson J, Muhlestein J, Bunch T, Knowlton K. The Impact Of Atrial Fibrillation At Time Of Cardiac Pet Stress Testing On Results, Coronary Outcomes, And Mace Journal of the American College of Cardiology. 73: 1478. DOI: 10.1016/S0735-1097(19)32084-4  0.347
2019 Meredith KG, Knight S, McCubrey R, Mason S, Min D, Biswas S, Anderson J, Muhlestein J, Knowlton K. PET/CT DERIVED ISCHEMIC BURDEN OF 10% PREDICTS OPTIMAL TREATMENT STRATEGY FOR SYMPTOMATIC CAD Journal of the American College of Cardiology. 73: 3. DOI: 10.1016/S0735-1097(19)30612-6  0.309
2018 Muhlestein JB, May HT, Galenko O, Knowlton KU, Otvos JD, Connelly MA, Lappe DL, Anderson JL. GlycA and hsCRP are independent and additive predictors of future cardiovascular events among patients undergoing angiography: The intermountain heart collaborative study. American Heart Journal. 202: 27-32. PMID 29803983 DOI: 10.1016/J.Ahj.2018.04.003  0.34
2018 Knight S, Min DB, Le VT, Meredith KG, Dhar R, Biswas S, Jensen KR, Mason SM, Ethington JD, Lappe DL, Muhlestein JB, Anderson JL, Knowlton KU. Implementation of a cardiac PET stress program: comparison of outcomes to the preceding SPECT era. Jci Insight. 3. PMID 29720565 DOI: 10.1172/Jci.Insight.120949  0.3
2018 Min DB, Mason S, Knight S, Ethington J, Le VT, Meredith K, Dhar R, Anderson J, Muhlestein J, Lappe D, Knowlton K. Transitioning From Cardiac Spect To Pet Myocardial Perfusion Imaging Resulted In Increased Ascertainment Of Individuals Requiring Revascularization Journal of the American College of Cardiology. 71. DOI: 10.1016/S0735-1097(18)32039-4  0.308
2018 Min DB, Mason S, Knight S, Ethington J, Le VT, Meredith K, Dhar R, Anderson J, Muhlestein J, Lappe D, Knowlton K. Cardiac Stress Testing Guides Subsequent Patient Management: Rates Of Coronary Angiography Based On Myocardial Perfusion Imaging Results Journal of the American College of Cardiology. 71. DOI: 10.1016/S0735-1097(18)32038-2  0.323
2018 Boralkar K, Kobayashi Y, Pargaonkar V, Moneghetti K, Tuzovic M, Krishnan G, Amsallem M, Kouznetsova T, Horne B, Knowlton K, Heidenreich P, Haddad F. THE COMPLEMENTARY VALUE OF THE GET WITH THE GUIDELINES: HEART FAILURE RISK SCORE AND LABORATORY MARKERS AT DISCHARGE IN PREDICTING MORTALITY IN PATIENTS HOSPITALIZED WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION Journal of the American College of Cardiology. 71: A839. DOI: 10.1016/S0735-1097(18)31380-9  0.313
2017 Muhlestein JB, May H, Galenko O, Knowlton K, Otvos J, Connelly M, Lappe D, Anderson J. Both The Novel Nmr Biomarker Of Inflammation, Glyca, And Hs-Crp Are Independent And Additive Predictors Of Future Cardiovascular Events Among Patients Undergoing Coronary Angiography: Results From The Intermountain Heart Collaborative Study Journal of the American College of Cardiology. 69: 1069. DOI: 10.1016/S0735-1097(17)34458-3  0.349
2017 Horne BD, Bunch TJ, May H, Knowlton K, Muhlestein JB, Graves KG, Jacobs V, Lappe D. IMPROVEMENT OF CHA2DS2-VASC RISK STRATIFICATION OF STROKE AND MORTALITY USING THE INTERMOUNTAIN RISK SCORE AMONG ATRIAL FIBRILLATION PATIENTS UNDERGOING CARDIAC CATHETERIZATION Journal of the American College of Cardiology. 69: 473. DOI: 10.1016/S0735-1097(17)33862-7  0.304
2016 Peter AK, Bradford WH, Dalton ND, Gu Y, Chao CJ, Peterson KL, Knowlton KU. Increased Echogenicity and Radiodense Foci on Echocardiogram and MicroCT in Murine Myocarditis. Plos One. 11: e0159971. PMID 27486657 DOI: 10.1371/Journal.Pone.0159971  0.312
2015 Lao DH, Esparza MC, Bremner SN, Banerjee I, Zhang J, Veevers J, Bradford WH, Gu Y, Dalton ND, Knowlton KU, Peterson KL, Lieber RL, Chen J. Lmo7 is dispensable for skeletal muscle and cardiac function. American Journal of Physiology. Cell Physiology. ajpcell.00177.2015. PMID 26157009 DOI: 10.1152/Ajpcell.00177.2015  0.304
2013 Lim BK, Peter AK, Xiong D, Narezkina A, Yung A, Dalton ND, Hwang KK, Yajima T, Chen J, Knowlton KU. Inhibition of Coxsackievirus-associated dystrophin cleavage prevents cardiomyopathy. The Journal of Clinical Investigation. 123: 5146-51. PMID 24200690 DOI: 10.1172/Jci66271  0.332
2012 Oba T, Yasukawa H, Hoshijima M, Sasaki K, Futamata N, Fukui D, Mawatari K, Nagata T, Kyogoku S, Ohshima H, Minami T, Nakamura K, Kang D, Yajima T, Knowlton KU, et al. Cardiac-specific deletion of SOCS-3 prevents development of left ventricular remodeling after acute myocardial infarction. Journal of the American College of Cardiology. 59: 838-52. PMID 22361405 DOI: 10.1016/J.Jacc.2011.10.887  0.32
2011 Yajima T, Murofushi Y, Zhou H, Park S, Housman J, Zhong ZH, Nakamura M, Machida M, Hwang KK, Gu Y, Dalton ND, Yajima T, Yasukawa H, Peterson KL, Knowlton KU. Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias. Circulation. 124: 2690-701. PMID 22082679 DOI: 10.1161/Circulationaha.111.028498  0.305
2011 Cheng H, Zheng M, Peter AK, Kimura K, Li X, Ouyang K, Shen T, Cui L, Frank D, Dalton ND, Gu Y, Frey N, Peterson KL, Evans SM, Knowlton KU, et al. Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy. Human Molecular Genetics. 20: 1751-62. PMID 21303826 DOI: 10.1093/Hmg/Ddr050  0.326
2009 Yajima T, Knowlton KU. Viral myocarditis: from the perspective of the virus. Circulation. 119: 2615-24. PMID 19451363 DOI: 10.1161/Circulationaha.108.766022  0.356
2009 Knowlton KU, Lim BK. Viral myocarditis: is infection of the heart required? Journal of the American College of Cardiology. 53: 1227-8. PMID 19341865 DOI: 10.1016/J.Jacc.2008.12.035  0.322
2009 Oba T, Yasukawa H, Sasaki K, Futamata N, Mawatari K, Kyougoku S, Nagata T, Hoshijima M, Knowlton K, Imaizumi T. Cardiac-Specific Deletion of SOCS3 Prevented Myocardial Apoptosis After Acute Myocardial Infarction Through Inhibiting Mitochondrial Damage Journal of Cardiac Failure. 15. DOI: 10.1016/J.Cardfail.2009.07.165  0.301
2008 Lim BK, Xiong D, Dorner A, Youn TJ, Yung A, Liu TI, Gu Y, Dalton ND, Wright AT, Evans SM, Chen J, Peterson KL, McCulloch AD, Yajima T, Knowlton KU. Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. The Journal of Clinical Investigation. 118: 2758-70. PMID 18636119 DOI: 10.1172/Jci34777  0.31
2007 Xiong D, Yajima T, Lim BK, Stenbit A, Dublin A, Dalton ND, Summers-Torres D, Molkentin JD, Duplain H, Wessely R, Chen J, Knowlton KU. Inducible cardiac-restricted expression of enteroviral protease 2A is sufficient to induce dilated cardiomyopathy. Circulation. 115: 94-102. PMID 17190866 DOI: 10.1161/Circulationaha.106.631093  0.303
2006 Yajima T, Yasukawa H, Jeon ES, Xiong D, Dorner A, Iwatate M, Nara M, Zhou H, Summers-Torres D, Hoshijima M, Chien KR, Yoshimura A, Knowlton KU. Innate defense mechanism against virus infection within the cardiac myocyte requiring gp130-STAT3 signaling. Circulation. 114: 2364-73. PMID 17101849 DOI: 10.1161/Circulationaha.106.642454  0.327
2006 Trifilo MJ, Yajima T, Gu Y, Dalton N, Peterson KL, Race RE, Meade-White K, Portis JL, Masliah E, Knowlton KU, Chesebro B, Oldstone MB. Prion-induced amyloid heart disease with high blood infectivity in transgenic mice. Science (New York, N.Y.). 313: 94-7. PMID 16825571 DOI: 10.1126/Science.1128635  0.334
2005 Lim BK, Shin JO, Lee SC, Kim DK, Choi DJ, Choe SC, Knowlton KU, Jeon ES. Long-term cardiac gene expression using a coxsackieviral vector. Journal of Molecular and Cellular Cardiology. 38: 745-51. PMID 15850568 DOI: 10.1016/J.Yjmcc.2005.02.018  0.339
2004 Knowlton KU, Yajima T. Interleukin-10: biomarker or pathologic cytokine in fulminant myocarditis? Journal of the American College of Cardiology. 44: 1298-300. PMID 15364335 DOI: 10.1016/J.Jacc.2004.06.026  0.306
2004 Badorff C, Knowlton KU. Dystrophin disruption in enterovirus-induced myocarditis and dilated cardiomyopathy: from bench to bedside. Medical Microbiology and Immunology. 193: 121-6. PMID 12920582 DOI: 10.1007/S00430-003-0189-7  0.346
2003 Yasukawa H, Yajima T, Duplain H, Iwatate M, Kido M, Hoshijima M, Weitzman MD, Nakamura T, Woodard S, Xiong D, Yoshimura A, Chien KR, Knowlton KU. The suppressor of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury. The Journal of Clinical Investigation. 111: 469-78. PMID 12588885 DOI: 10.1172/Jci16491  0.363
2002 Xiong D, Lee GH, Badorff C, Dorner A, Lee S, Wolf P, Knowlton KU. Dystrophin deficiency markedly increases enterovirus-induced cardiomyopathy: a genetic predisposition to viral heart disease. Nature Medicine. 8: 872-7. PMID 12118246 DOI: 10.1038/Nm737  0.334
2002 Ryoke T, Gu Y, Ikeda Y, Martone ME, Oh SS, Jeon ES, Knowlton KU, Ross J. Apoptosis and oncosis in the early progression of left ventricular dysfunction in the cardiomyopathic hamster. Basic Research in Cardiology. 97: 65-75. PMID 12004790 DOI: 10.1007/S395-002-8389-4  0.305
2000 Knowlton KU. The immune response following myocardial infarction: a role for T-cell-mediated myocyte damage. Journal of Molecular and Cellular Cardiology. 32: 2107-2110. PMID 11112986 DOI: 10.1006/Jmcc.2000.1284  0.324
2000 Lee G, Badorff C, Knowlton KU. Dissociation of Sarcoglycans and the Dystrophin Carboxyl Terminus From the Sarcolemma in Enteroviral Cardiomyopathy Circulation Research. 87: 489-495. PMID 10988241 DOI: 10.1161/01.Res.87.6.489  0.331
1999 Knowlton KU, Badorff C. The immune system in viral myocarditis: maintaining the balance. Circulation Research. 85: 559-561. PMID 10488059 DOI: 10.1161/01.Res.85.6.559  0.338
1999 Badorff C, Lee GH, Lamphear BJ, Martone ME, Campbell KP, Rhoads RE, Knowlton KU. Enteroviral protease 2A cleaves dystrophin: evidence of cytoskeletal disruption in an acquired cardiomyopathy. Nature Medicine. 5: 320-6. PMID 10086389 DOI: 10.1038/6543  0.335
1998 Wessely R, Klingel K, Santana LF, Dalton N, Hongo M, Lederer WJ, Kandolf R, Knowlton KU. Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy Journal of Clinical Investigation. 102: 1444-1453. PMID 9769337 DOI: 10.1172/Jci1972  0.377
1998 Wessely R, Henke A, Zell R, Kandolf R, Knowlton KU. Low-Level Expression of a Mutant Coxsackieviral cDNA Induces a Myocytopathic Effect in Culture An Approach to the Study of Enteroviral Persistence in Cardiac Myocytes Circulation. 98: 450-457. PMID 9714096 DOI: 10.1161/01.Cir.98.5.450  0.347
1995 Knowlton KU, Rockman HA, Itani M, Vovan A, Seidman CE, Chien KR. Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium Journal of Clinical Investigation. 96: 1311-1318. PMID 7657806 DOI: 10.1172/Jci118166  0.3
1992 Ross RS, Knowlton KU. Two Brothers with Unexplained Cardiomegaly Initial Clues to the Molecular Basis of a Hereditary Cardiac Disease Trends in Cardiovascular Medicine. 2: 2-5. PMID 21239280 DOI: 10.1016/1050-1738(92)90036-R  0.352
1992 Chien KR, Knowlton KU, Zhu H, Chien S. Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 3037-46. PMID 1835945 DOI: 10.1096/Fasebj.5.15.1835945  0.33
1991 Rockman HA, Ross RS, Harris AN, Knowlton KU, Steinhelper ME, Field LJ, Ross J, Chien KR. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 88: 8277-81. PMID 1832775 DOI: 10.1073/Pnas.88.18.8277  0.317
1991 Rockman HA, Ross RS, Harris AN, Knowlton KU, Steinhelper ME, Field LJ, Ross J. Corrections and Retraction: Segregation of Atrial-Specific and Inducible Expression of an Atrial Natriuretic Factor Transgene in an In vivo Murine Model of Cardiac Hypertrophy Proceedings of the National Academy of Sciences of the United States of America. 88: 9907. DOI: 10.1073/Pnas.88.21.9907A  0.324
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