Stephen Schaffer - Publications

Affiliations: 
College of Medicine University of South Alabama, Mobile, AL, United States 
Area:
Pharmacology, Molecular Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Schaffer SW, Jong CJ, Ramila KC, Ito T, Kramer J. Differences Between Physiological and Pharmacological Actions of Taurine. Advances in Experimental Medicine and Biology. 1370: 311-321. PMID 35882806 DOI: 10.1007/978-3-030-93337-1_30  0.726
2021 Jong CJ, Sandal P, Schaffer SW. The Role of Taurine in Mitochondria Health: More Than Just an Antioxidant. Molecules (Basel, Switzerland). 26. PMID 34443494 DOI: 10.3390/molecules26164913  0.735
2020 Schaffer S, Ito T, Azuma J, Jong C, Kramer J. Mechanisms Underlying Development of Taurine-Deficient Cardiomyopathy Hearts. 1: 86-98. DOI: 10.3390/hearts1020010  0.402
2018 Schaffer S, Kim HW. Effects and Mechanisms of Taurine as a Therapeutic Agent. Biomolecules & Therapeutics. 26: 225-241. PMID 29631391 DOI: 10.4062/Biomolther.2017.251  0.414
2017 Ito T, Okazaki K, Nakajima D, Shibata D, Murakami S, Schaffer S. Mass spectrometry-based metabolomics to identify taurine-modified metabolites in heart. Amino Acids. PMID 29019072 DOI: 10.1007/S00726-017-2498-Y  0.4
2017 Shimada-Takaura K, Takahashi K, Ito T, Schaffer S. Role for Taurine in Development of Oxidative Metabolism After Birth. Advances in Experimental Medicine and Biology. 975: 1047-1057. PMID 28849521 DOI: 10.1007/978-94-024-1079-2_83  0.445
2017 Schaffer S, Jong CJ, Shetewy A, Ramila KC, Ito T. Impaired Energy Production Contributes to Development of Failure in Taurine Deficient Heart. Advances in Experimental Medicine and Biology. 975: 435-446. PMID 28849473 DOI: 10.1007/978-94-024-1079-2_35  0.752
2017 Jong CJ, Ito T, Prentice H, Wu JY, Schaffer SW. Role of Mitochondria and Endoplasmic Reticulum in Taurine-Deficiency-Mediated Apoptosis. Nutrients. 9. PMID 28757580 DOI: 10.3390/Nu9080795  0.751
2016 Shetewy A, Shimada-Takaura K, Warner D, Jong CJ, Mehdi AB, Alexeyev M, Takahashi K, Schaffer SW. Mitochondrial defects associated with β-alanine toxicity: relevance to hyper-beta-alaninemia. Molecular and Cellular Biochemistry. 416: 11-22. PMID 27023909 DOI: 10.1007/S11010-016-2688-Z  0.731
2016 Shetewy A, Shimada-Takaura K, Warner D, Jong CJ, Mehdi ABA, Alexeyev M, Takahashi K, Schaffer SW. Mitochondrial defects associated with β-alanine toxicity: relevance to hyper-beta-alaninemia Molecular and Cellular Biochemistry. 1-12. DOI: 10.1007/s11010-016-2688-z  0.731
2015 Schaffer SW, Shimada-Takaura K, Jong CJ, Ito T, Takahashi K. Impaired energy metabolism of the taurine-deficient heart. Amino Acids. PMID 26475290 DOI: 10.1007/S00726-015-2110-2  0.751
2015 Jong CJ, Ito T, Schaffer SW. The ubiquitin-proteasome system and autophagy are defective in the taurine-deficient heart. Amino Acids. 47: 2609-22. PMID 26193770 DOI: 10.1007/S00726-015-2053-7  0.759
2015 Shimada K, Jong CJ, Takahashi K, Schaffer SW. Role of ROS Production and Turnover in the Antioxidant Activity of Taurine. Advances in Experimental Medicine and Biology. 803: 581-96. PMID 25833529 DOI: 10.1007/978-3-319-15126-7_47  0.731
2015 Jong CJ, Ito T, Azuma J, Schaffer S. Taurine Depletion Decreases GRP78 Expression and Downregulates Perk-Dependent Activation of the Unfolded Protein Response. Advances in Experimental Medicine and Biology. 803: 571-9. PMID 25833528 DOI: 10.1007/978-3-319-15126-7_46  0.726
2015 Schaffer SW, Ramila KC, Jong CJ, Shetewy A, Shimada K, Ito T, Azuma J, Cioffi E. Does taurine prolong lifespan by improving heart function? Advances in Experimental Medicine and Biology. 803: 555-70. PMID 25833527 DOI: 10.1007/978-3-319-15126-7_45  0.734
2015 Ito T, Miyazaki N, Schaffer S, Azuma J. Potential Anti-aging Role of Taurine via Proper Protein Folding: A Study from Taurine Transporter Knockout Mouse. Advances in Experimental Medicine and Biology. 803: 481-7. PMID 25833520 DOI: 10.1007/978-3-319-15126-7_38  0.315
2015 Ramila KC, Jong CJ, Pastukh V, Ito T, Azuma J, Schaffer SW. Role of protein phosphorylation in excitation-contraction coupling in taurine deficient hearts. American Journal of Physiology. Heart and Circulatory Physiology. 308: H232-9. PMID 25437920 DOI: 10.1152/Ajpheart.00497.2014  0.715
2015 Schaffer SW, Jong CJ. Regulation of cardiac hypertrophy by t-type ca2+ channel T-Type Calcium Channels in Basic and Clinical Science. 73-84. DOI: 10.1007/978-3-7091-1413-1_5  0.688
2014 Schaffer SW, Shimada K, Jong CJ, Ito T, Azuma J, Takahashi K. Effect of taurine and potential interactions with caffeine on cardiovascular function. Amino Acids. 46: 1147-57. PMID 24615238 DOI: 10.1007/S00726-014-1708-0  0.67
2014 Ito T, Schaffer S, Azuma J. The effect of taurine on chronic heart failure: actions of taurine against catecholamine and angiotensin II. Amino Acids. 46: 111-9. PMID 23722414 DOI: 10.1007/S00726-013-1507-Z  0.37
2014 Isfort M, Stevens SC, Schaffer S, Jong CJ, Wold LE. Metabolic dysfunction in diabetic cardiomyopathy. Heart Failure Reviews. 19: 35-48. PMID 23443849 DOI: 10.1007/S10741-013-9377-8  0.7
2014 Schaffer SW, Jong CJ, Ito T, Azuma J. Role of taurine in the pathologies of MELAS and MERRF. Amino Acids. 46: 47-56. PMID 23179085 DOI: 10.1007/S00726-012-1414-8  0.718
2014 Schaffer SW, Jong CJ, Ito T, Azuma J. Effect of taurine on ischemia-reperfusion injury. Amino Acids. 46: 21-30. PMID 22936072 DOI: 10.1007/S00726-012-1378-8  0.723
2013 Schaffer SW, Jong CJ, Warner D, Ito T, Azuma J. Taurine deficiency and MELAS are closely related syndromes. Advances in Experimental Medicine and Biology. 776: 153-65. PMID 23392880 DOI: 10.1007/978-1-4614-6093-0_16  0.705
2013 Jong CJ, Schaffer S. Mechanism underlying the antioxidant activity of taurine The Faseb Journal. 27. DOI: 10.1096/Fasebj.27.1_Supplement.1086.1  0.71
2012 Ata H, Shrestha D, Oka M, Ochi R, Jong CJ, Gebb S, Benjamin J, Schaffer S, Hobart HH, Downey J, McMurtry I, Gupte R. Down-regulation of replication factor C-40 (RFC40) causes chromosomal missegregation in neonatal and hypertrophic adult rat cardiac myocytes. Plos One. 7: e39009. PMID 22720015 DOI: 10.1371/Journal.Pone.0039009  0.691
2012 Schaffer SW, Jong CJ, Mozaffari M. Role of oxidative stress in diabetes-mediated vascular dysfunction: unifying hypothesis of diabetes revisited. Vascular Pharmacology. 57: 139-49. PMID 22480621 DOI: 10.1016/J.Vph.2012.03.005  0.696
2012 Jong CJ, Azuma J, Schaffer S. Mechanism underlying the antioxidant activity of taurine: prevention of mitochondrial oxidant production. Amino Acids. 42: 2223-32. PMID 21691752 DOI: 10.1007/S00726-011-0962-7  0.747
2012 Jong CJ, Ramila K, Ito T, Azuma J, Schaffer S. The role of a taurine-containing wobble modification deficiency in MELAS Mitochondrion. 12: 554-555. DOI: 10.1016/J.Mito.2012.07.013  0.69
2011 Jong CJ, Azuma J, Schaffer SW. Role of mitochondrial permeability transition in taurine deficiency-induced apoptosis. Experimental and Clinical Cardiology. 16: 125-8. PMID 22131855  0.735
2010 Jong CJ, Ito T, Mozaffari M, Azuma J, Schaffer S. Effect of beta-alanine treatment on mitochondrial taurine level and 5-taurinomethyluridine content. Journal of Biomedical Science. 17: S25. PMID 20804600 DOI: 10.1186/1423-0127-17-S1-S25  0.74
2010 Schaffer SW, Jong CJ, Ramila KC, Azuma J. Physiological roles of taurine in heart and muscle. Journal of Biomedical Science. 17: S2. PMID 20804594 DOI: 10.1186/1423-0127-17-S1-S2  0.727
2010 Pastukh V, Chen H, Wu S, Jong CJ, Alexeyev M, Schaffer SW. Effect of hypernatremia on injury caused by energy deficiency: role of T-type Ca2+ channel. American Journal of Physiology. Cell Physiology. 299: C289-97. PMID 20505041 DOI: 10.1152/Ajpcell.00362.2009  0.698
2009 Schaffer SW, Azuma J, Mozaffari M. Role of antioxidant activity of taurine in diabetes. Canadian Journal of Physiology and Pharmacology. 87: 91-9. PMID 19234572 DOI: 10.1139/Y08-110  0.343
2008 Ricci C, Jong CJ, Schaffer SW. Proapoptotic and antiapoptotic effects of hyperglycemia: role of insulin signaling. Canadian Journal of Physiology and Pharmacology. 86: 166-72. PMID 18418425 DOI: 10.1139/Y08-021  0.672
2008 Ito T, Kimura Y, Uozumi Y, Takai M, Muraoka S, Matsuda T, Ueki K, Yoshiyama M, Ikawa M, Okabe M, Schaffer SW, Fujio Y, Azuma J. Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy. Journal of Molecular and Cellular Cardiology. 44: 927-37. PMID 18407290 DOI: 10.1016/j.yjmcc.2008.03.001  0.323
2005 Pastukh V, Wu S, Ricci C, Mozaffari M, Schaffer S. Reversal of hyperglycemic preconditioning by angiotensin II: role of calcium transport. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1965-75. PMID 15604129 DOI: 10.1152/Ajpheart.00855.2004  0.365
2003 Grishko V, Pastukh V, Solodushko V, Gillespie M, Azuma J, Schaffer S. Apoptotic cascade initiated by angiotensin II in neonatal cardiomyocytes: role of DNA damage. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2364-72. PMID 12919932 DOI: 10.1152/Ajpheart.00408.2003  0.308
2003 Schaffer S, Azuma J, Takahashi K, Mozaffari M. Why is taurine cytoprotective? Advances in Experimental Medicine and Biology. 526: 307-21. PMID 12908615 DOI: 10.1007/978-1-4615-0077-3_39  0.406
2003 Singh RB, Kartikey K, Charu AS, Niaz MA, Schaffer S. Effect of taurine and coenzyme Q10 in patients with acute myocardial infarction. Advances in Experimental Medicine and Biology. 526: 41-48. PMID 12908582 DOI: 10.1007/978-1-4615-0077-3_6  0.356
2003 Schaffer S, Solodushko V, Pastukh V, Ricci C, Azuma J. Possible cause of taurine-deficient cardiomyopathy: potentiation of angiotensin II action. Journal of Cardiovascular Pharmacology. 41: 751-9. PMID 12717106 DOI: 10.1097/00005344-200305000-00012  0.363
2002 Schaffer S, Solodushko V, Azuma J. Taurine-deficient cardiomyopathy: role of phospholipids, calcium and osmotic stress. Advances in Experimental Medicine and Biology. 483: 57-69. PMID 11787642 DOI: 10.1007/0-306-46838-7_6  0.324
2001 Schaffer S, Takahashi K, Azuma J. Role of osmoregulation in the actions of taurine. Amino Acids. 19: 527-46. PMID 11140357 DOI: 10.1007/S007260070004  0.361
2000 Schaffer SW, Lombardini JB, Azuma J. Interaction between the actions of taurine and angiotensin II. Amino Acids. 18: 305-18. PMID 10949914 DOI: 10.1007/PL00010320  0.312
1998 Takahahsi K, Azuma M, Baba A, Schaffer S, Azuma J. Taurine improves angiotensin II-induced hypertrophy of cultured neonatal rat heart cells. Advances in Experimental Medicine and Biology. 442: 129-35. PMID 9635024 DOI: 10.1007/978-1-4899-0117-0_17  0.316
1997 Ballard-Croft C, Mozaffari MS, Azuma J, Schaffer S. Interaction between taurine and angiotensin II: Modulation of calcium transport and myocardial contractile function Amino Acids. 13: 105-114. DOI: 10.1007/Bf01373209  0.363
1996 Ballard C, Schaffer S. Stimulation of the Na+/Ca2 +Exchanger by Phenylephrine, Angiotensin II and Endothelin 1 Journal of Molecular and Cellular Cardiology. 28: 11-17. PMID 8745210 DOI: 10.1006/Jmcc.1996.0002  0.331
1995 Ballard C, Mozaffari M, Schaffer S. Signal transduction mechanism for the stimulation of the sarcolemmal Na(+)-Ca2+ exchanger by insulin. Molecular and Cellular Biochemistry. 135: 113-9. PMID 7816053 DOI: 10.1007/Bf00925967  0.311
1994 Punna S, Ballard C, Hamaguchi T, Azuma J, Schaffer S. Effect of taurine and methionine on sarcoplasmic reticular Ca2+ transport and phospholipid methyltransferase activity. Journal of Cardiovascular Pharmacology. 24: 286-292. DOI: 10.1097/00005344-199408000-00014  0.351
1992 Hamaguchi T, Azumal J, Schaffer S. Sarcolemmal actions of taurine linked to altered phospholipid N-methylation. Advances in Experimental Medicine and Biology. 315: 121-128. PMID 1509931 DOI: 10.1007/978-1-4615-3436-5_14  0.355
1991 Hamaguchi T, Azuma J, Schaffer S. Interaction of taurine with methionine: inhibition of myocardial phospholipid methyltransferase. Journal of Cardiovascular Pharmacology. 18: 224-230. PMID 1717783 DOI: 10.1097/00005344-199108000-00008  0.358
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