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Rhiannon N. Hardwick, Ph.D. - Publications

Affiliations: 
2012 Pharmacology & Toxicology University of Arizona, Tucson, AZ 
Area:
Toxicology, Pharmacy, Pharmacology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lim AY, Kato Y, Sakolish C, Valdiviezo A, Han G, Bajaj P, Stanko J, Ferguson SS, Villenave R, Hewitt P, Hardwick RN, Rusyn I. Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations. Bioengineering (Basel, Switzerland). 10. PMID 37892925 DOI: 10.3390/bioengineering10101195  0.367
2020 Letertre MPM, Munjoma N, Wolfer K, Pechlivanis A, McDonald JAK, Hardwick R, Cherrington NJ, Coen M, Nicholson JK, Hoyles L, Swann JR, Wilson ID. A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats. Journal of Proteome Research. PMID 32544340 DOI: 10.1021/Acs.Jproteome.0C00230  0.622
2019 Lake AD, Hardwick RN, Leamon CP, Low PS, Cherrington NJ. Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatitis. Toxicology and Applied Pharmacology. PMID 30794826 DOI: 10.1016/J.Taap.2019.02.009  0.815
2017 Clarke JD, Novak P, Lake AD, Hardwick RN, Cherrington NJ. Impaired N-linked Glycosylation of Uptake and Efflux Transporters in Human Nonalcoholic Fatty Liver Disease. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 28097795 DOI: 10.1111/Liv.13362  0.847
2017 Irelan J, Crogan-Grundy C, Smith R, Hardwick R, Nguyen D. Evaluation of 3-D bioprinted human liver tissue for assessment drug-induced liver injury across a diverse set of chemical classes Toxicology Letters. 280: S270. DOI: 10.1016/j.toxlet.2017.07.954  0.388
2016 Hardwick RN, Snellings M, Ferslew BC, Lu Y, Browuer KL. Tyrosine and aurora kinase inhibitors diminish transport function of multidrug resistance-associated protein (MRP) 4 and breast cancer resistance protein (BCRP) Admet and Dmpk. 4: 302. DOI: 10.5599/Admet.4.4.322  0.368
2015 Canet MJ, Merrell MD, Hardwick RN, Bataille AM, Campion SN, Ferreira DW, Xanthakos SA, Manautou JE, Hesham A-Kader H, Erickson RP, Cherrington NJ. Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 829-35. PMID 25788542 DOI: 10.1124/Dmd.114.062703  0.824
2015 Canet MJ, Hardwick RN, Lake AD, Dzierlenga AL, Clarke JD, Goedken MJ, Cherrington NJ. Renal xenobiotic transporter expression is altered in multiple experimental models of nonalcoholic steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 266-72. PMID 25488932 DOI: 10.1124/Dmd.114.060574  0.82
2014 Kyriakides M, Hardwick RN, Jin Z, Goedken MJ, Holmes E, Cherrington NJ, Coen M. Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 105-16. PMID 25145655 DOI: 10.1093/Toxsci/Kfu160  0.734
2014 Hardwick RN, Clarke JD, Lake AD, Canet MJ, Anumol T, Street SM, Merrell MD, Goedken MJ, Snyder SA, Cherrington NJ. Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 45-55. PMID 25080921 DOI: 10.1093/Toxsci/Kfu156  0.781
2014 Clarke JD, Hardwick RN, Lake AD, Lickteig AJ, Goedken MJ, Klaassen CD, Cherrington NJ. Synergistic interaction between genetics and disease on pravastatin disposition. Journal of Hepatology. 61: 139-47. PMID 24613363 DOI: 10.1016/J.Jhep.2014.02.021  0.807
2014 Yang K, Pfeifer ND, Hardwick RN, Yue W, Stewart PW, Brouwer KL. An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown. Molecular Pharmaceutics. 11: 766-75. PMID 24410402 DOI: 10.1021/Mp400471E  0.489
2014 Clarke JD, Hardwick RN, Lake AD, Canet MJ, Cherrington NJ. Experimental nonalcoholic steatohepatitis increases exposure to simvastatin hydroxy acid by decreasing hepatic organic anion transporting polypeptide expression. The Journal of Pharmacology and Experimental Therapeutics. 348: 452-8. PMID 24403518 DOI: 10.1124/Jpet.113.211284  0.84
2014 Canet MJ, Hardwick RN, Lake AD, Dzierlenga AL, Clarke JD, Cherrington NJ. Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 586-95. PMID 24384915 DOI: 10.1124/Dmd.113.055996  0.813
2014 Pfeifer ND, Hardwick RN, Brouwer KL. Role of hepatic efflux transporters in regulating systemic and hepatocyte exposure to xenobiotics. Annual Review of Pharmacology and Toxicology. 54: 509-35. PMID 24160696 DOI: 10.1146/Annurev-Pharmtox-011613-140021  0.578
2014 Lake AD, Novak P, Hardwick RN, Flores-Keown B, Zhao F, Klimecki WT, Cherrington NJ. The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 26-35. PMID 24097666 DOI: 10.1093/Toxsci/Kft230  0.809
2014 Sanchez-Soria P, Broka D, Quach S, Hardwick RN, Cherrington NJ, Camenisch TD. Fetal exposure to arsenic results in hyperglycemia, hypercholesterolemia, and nonalcoholic fatty liver disease in adult mice Journal of Toxicology and Health. 1: 1. DOI: 10.7243/2056-3779-1-1  0.342
2013 Pfeifer ND, Bridges AS, Ferslew BC, Hardwick RN, Brouwer KL. Hepatic basolateral efflux contributes significantly to rosuvastatin disposition II: characterization of hepatic elimination by basolateral, biliary, and metabolic clearance pathways in rat isolated perfused liver. The Journal of Pharmacology and Experimental Therapeutics. 347: 737-45. PMID 24080682 DOI: 10.1124/Jpet.113.208314  0.566
2013 Klein DM, Evans KK, Hardwick RN, Dantzler WH, Wright SH, Cherrington NJ. Basolateral uptake of nucleosides by Sertoli cells is mediated primarily by equilibrative nucleoside transporter 1. The Journal of Pharmacology and Experimental Therapeutics. 346: 121-9. PMID 23639800 DOI: 10.1124/Jpet.113.203265  0.681
2013 Hardwick RN, Ferreira DW, More VR, Lake AD, Lu Z, Manautou JE, Slitt AL, Cherrington NJ. Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 554-61. PMID 23223517 DOI: 10.1124/Dmd.112.048439  0.834
2013 Cherrington NJ, Estrada TE, Frisk HA, Canet MJ, Hardwick RN, Dvorak B, Lux K, Halpern MD. The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G48-56. PMID 23125159 DOI: 10.1152/Ajpgi.00317.2012  0.827
2012 Canet MJ, Hardwick RN, Lake AD, Kopplin MJ, Scheffer GL, Klimecki WT, Gandolfi AJ, Cherrington NJ. Altered arsenic disposition in experimental nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1817-24. PMID 22699396 DOI: 10.1124/Dmd.112.046177  0.821
2012 Hardwick RN, Cherrington NJ. Measuring altered disposition of xenobiotics in experimental models of liver disease. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit 23.1.. PMID 22549269 DOI: 10.1002/0471140856.Tx2301S52  0.746
2012 Druwe IL, Sollome JJ, Sanchez-Soria P, Hardwick RN, Camenisch TD, Vaillancourt RR. Arsenite activates NFκB through induction of C-reactive protein. Toxicology and Applied Pharmacology. 261: 263-70. PMID 22521605 DOI: 10.1016/J.Taap.2012.04.005  0.381
2012 Hardwick RN, Fisher CD, Street SM, Canet MJ, Cherrington NJ. Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 450-60. PMID 22112382 DOI: 10.1124/Dmd.111.041095  0.823
2012 Jelinek DA, Maghsoodi B, Borbon IA, Hardwick RN, Cherrington NJ, Erickson RP. Genetic variation in the mouse model of Niemann Pick C1 affects female, as well as male, adiposity, and hepatic bile transporters but has indeterminate effects on caveolae. Gene. 491: 128-34. PMID 22020183 DOI: 10.1016/J.Gene.2011.10.010  0.638
2011 Hardwick RN, Fisher CD, Canet MJ, Scheffer GL, Cherrington NJ. Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 2395-402. PMID 21878559 DOI: 10.1124/Dmd.111.041012  0.843
2011 Lake AD, Novak P, Fisher CD, Jackson JP, Hardwick RN, Billheimer DD, Klimecki WT, Cherrington NJ. Analysis of global and absorption, distribution, metabolism, and elimination gene expression in the progressive stages of human nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1954-60. PMID 21737566 DOI: 10.1124/Dmd.111.040592  0.826
2010 Hardwick RN, Fisher CD, Canet MJ, Lake AD, Cherrington NJ. Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2293-301. PMID 20805291 DOI: 10.1124/Dmd.110.035006  0.779
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