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Daniel J. Sprague, M.D., Ph.D. - Publications

Affiliations: 
Cell Biology, Neurobiology, and Anatomy Medical College of Wisconsin 
Area:
Synthetic Chemistry
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Park SK, Sprague DJ, Rohr CM, Chulkov EG, Petrow I, Kumar S, Marchant JS. The anthelmintic meclonazepam activates a schistosome transient receptor potential channel. The Journal of Biological Chemistry. 300: 105528. PMID 38043794 DOI: 10.1016/j.jbc.2023.105528  0.545
2023 Sprague DJ, Kaethner M, Park SK, Rohr CM, Harris JL, Maillard D, Spangenberg T, Lundström-Stadelmann B, Marchant JS. The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPM Orthologs. Acs Medicinal Chemistry Letters. 14: 1537-1543. PMID 37970586 DOI: 10.1021/acsmedchemlett.3c00350  0.53
2023 Sprague DJ, Park SK, Gramberg S, Bauer L, Rohr CM, Chulkov EG, Smith E, Scampavia L, Spicer TP, Haeberlein S, Marchant JS. Target-based discovery of a broad spectrum flukicide. Biorxiv : the Preprint Server For Biology. PMID 37790347 DOI: 10.1101/2023.09.22.559026  0.547
2023 Malcolm NJ, Palkovic B, Sprague DJ, Calkins MM, Lanham JK, Halberstadt AL, Stucke AG, McCorvy JD. Mu-opioid receptor selective superagonists produce prolonged respiratory depression. Iscience. 26: 107121. PMID 37416459 DOI: 10.1016/j.isci.2023.107121  0.548
2023 Yahya NA, Lanham JK, Sprague DJ, Palygin O, McCorvy JD, Marchant JS. Molecular and cellular basis of praziquantel action in the cardiovascular system. American Journal of Physiology. Cell Physiology. PMID 36622066 DOI: 10.1152/ajpcell.00520.2022  0.638
2022 Rohr CM, Sprague DJ, Park SK, Malcolm NJ, Marchant JS. Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217732120. PMID 36574686 DOI: 10.1073/pnas.2217732120  0.531
2022 AbuEid M, Keyes RF, McAllister D, Peterson F, Kadamberi IP, Sprague DJ, Chaluvally-Raghavan P, Smith BC, Dwinell MB. Fluorinated triphenylphosphonium analogs improve cell selectivity and detection of mito-metformin. Iscience. 25: 105670. PMID 36567718 DOI: 10.1016/j.isci.2022.105670  0.425
2021 Gunaratne GS, Rebbeck RT, McGurran LM, Yan Y, Arzua T, Frolkis T, Sprague DJ, Bai X, Cornea RL, Walseth TF, Marchant JS. Identification of a dihydropyridine scaffold that blocks ryanodine receptors. Iscience. 25: 103706. PMID 35059610 DOI: 10.1016/j.isci.2021.103706  0.512
2021 Sprague DJ, Getschman AE, Fenske TG, Volkman BF, Smith BC. Trisubstituted 1,3,5-Triazines: The First Ligands of the sY12-Binding Pocket on Chemokine CXCL12. Acs Medicinal Chemistry Letters. 12: 1773-1782. PMID 34795867 DOI: 10.1021/acsmedchemlett.1c00388  0.625
2020 Sprague DJ, Johnston JN. Substituted Imidazoline Synthesis: A Diastereo- and Enantioselective aza-Henry Route to a Human Proteasome Modulator. Organic Letters. PMID 33054232 DOI: 10.1021/acs.orglett.0c03096  0.509
2020 Goetz CJ, Sprague DJ, Smith BC. Development of activity-based probes for the protein deacylase Sirt1. Bioorganic Chemistry. 104: 104232. PMID 32911193 DOI: 10.1016/J.Bioorg.2020.104232  0.448
2020 Olp MD, Sprague DJ, Goetz CJ, Kathman SG, Wynia-Smith SL, Shishodia S, Summers SB, Xu Z, Statsyuk AV, Smith BC. Covalent-fragment screening of BRD4 identifies a ligandable site orthogonal to the acetyl-lysine binding sites. Acs Chemical Biology. PMID 32149490 DOI: 10.1021/Acschembio.0C00058  0.466
2018 Sprague DJ, Singh A, Johnston JN. Diastereo- and enantioselective additions of α-nitro esters to imines for -α,β-diamino acid synthesis with α-alkyl-substitution. Chemical Science. 9: 2336-2339. PMID 29719706 DOI: 10.1039/C7Sc05176J  0.607
2015 Sprague DJ, Nugent BM, Yoder RA, Vara BA, Johnston JN. Adaptation of a small-molecule hydrogen-bond donor catalyst to an enantioselective hetero-Diels-Alder reaction hypothesized for brevianamide biosynthesis. Organic Letters. 17: 880-3. PMID 25697748 DOI: 10.1021/Ol503626W  0.589
2012 Narcis MJ, Sprague DJ, Captain B, Takenaka N. Enantio- and periselective nitroalkene Diels-Alder reaction. Organic & Biomolecular Chemistry. 10: 9134-6. PMID 23104427 DOI: 10.1039/C2Ob26674A  0.365
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