John W. Sedat - Publications

Affiliations: 
Biochemistry & Biophysics University of California, San Francisco, San Francisco, CA 
Area:
Nuclear Architecture and Chromosome Organization
Website:
http://msg.ucsf.edu/sedat/

156 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Croxford M, Elbaum M, Arigovindan M, Kam Z, Agard D, Villa E, Sedat J. Entropy-regularized deconvolution of cellular cryotransmission electron tomograms. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34876518 DOI: 10.1073/pnas.2108738118  0.44
2020 Waugh B, Wolf SG, Fass D, Branlund E, Kam Z, Sedat JW, Elbaum M. Three-dimensional deconvolution processing for STEM cryotomography. Proceedings of the National Academy of Sciences of the United States of America. PMID 33077585 DOI: 10.1073/pnas.2000700117  0.301
2013 Arigovindan M, Fung JC, Elnatan D, Mennella V, Chan YH, Pollard M, Branlund E, Sedat JW, Agard DA. High-resolution restoration of 3D structures from widefield images with extreme low signal-to-noise-ratio. Proceedings of the National Academy of Sciences of the United States of America. 110: 17344-9. PMID 24106307 DOI: 10.1073/Pnas.1315675110  0.586
2012 Nora EP, Lajoie BR, Schulz EG, Giorgetti L, Okamoto I, Servant N, Piolot T, Van Berkum NL, Meisig J, Sedat J, Gribnau J, Barillot E, Blüthgen N, Dekker J, Heard E. Spatial partitioning of the regulatory landscape of the X-inactivation centre Nature. 485: 381-385. PMID 22495304 DOI: 10.1038/Nature11049  0.349
2012 Shao L, Winoto L, Agard DA, Gustafsson MG, Sedat JW. Interferometer-based structured-illumination microscopy utilizing complementary phase relationship through constructive and destructive image detection by two cameras. Journal of Microscopy. 246: 229-36. PMID 22472010 DOI: 10.1111/J.1365-2818.2012.03604.X  0.659
2012 Arigovindan M, Sedat JW, Agard DA. Effect of depth dependent spherical aberrations in 3D structured illumination microscopy. Optics Express. 20: 6527-41. PMID 22418536 DOI: 10.1364/Oe.20.006527  0.521
2011 Dobbie IM, King E, Parton RM, Carlton PM, Sedat JW, Swedlow JR, Davis I. OMX: a new platform for multimodal, multichannel wide-field imaging. Cold Spring Harbor Protocols. 2011: 899-909. PMID 21807861 DOI: 10.1101/Pdb.Top121  0.701
2011 Zheng SQ, Branlund E, Kesthelyi B, Braunfeld MB, Cheng Y, Sedat JW, Agard DA. A distributed multi-GPU system for high speed electron microscopic tomographic reconstruction. Ultramicroscopy. 111: 1137-43. PMID 21741915 DOI: 10.1016/J.Ultramic.2011.03.015  0.502
2011 Strukov YG, Sural TH, Kuroda MI, Sedat JW. Evidence of activity-specific, radial organization of mitotic chromosomes in Drosophila. Plos Biology. 9: e1000574. PMID 21264350 DOI: 10.1371/Journal.Pbio.1000574  0.799
2011 Kner P, Kam Z, Agard D, Sedat J. Adaptive optics in wide-field microscopy Proceedings of Spie - the International Society For Optical Engineering. 7931. DOI: 10.1117/12.876500  0.773
2010 Kner P, Winoto L, Agard DA, Sedat JW. Closed loop adaptive optics for microscopy without a wavefront sensor. Proceedings of Spie--the International Society For Optical Engineering. 7570. PMID 24392198 DOI: 10.1117/12.840943  0.797
2010 Zheng SQ, Sedat JW, Agard DA. Automated data collection for electron microscopic tomography. Methods in Enzymology. 481: 283-315. PMID 20887862 DOI: 10.1016/S0076-6879(10)81012-2  0.515
2010 Matsuda A, Shao L, Boulanger J, Kervrann C, Carlton PM, Kner P, Agard D, Sedat JW. Condensed mitotic chromosome structure at nanometer resolution using PALM and EGFP- histones. Plos One. 5: e12768. PMID 20856676 DOI: 10.1371/Journal.Pone.0012768  0.813
2010 Carlton PM, Boulanger J, Kervrann C, Sibarita JB, Salamero J, Gordon-Messer S, Bressan D, Haber JE, Haase S, Shao L, Winoto L, Matsuda A, Kner P, Uzawa S, Gustafsson M, ... ... Sedat JW, et al. Fast live simultaneous multiwavelength four-dimensional optical microscopy. Proceedings of the National Academy of Sciences of the United States of America. 107: 16016-22. PMID 20705899 DOI: 10.1073/Pnas.1004037107  0.806
2010 Arigovindan M, Shaevitz J, McGowan J, Sedat JW, Agard DA. A Parallel Product-Convolution approach for representing the depth varying Point Spread Functions in 3D widefield microscopy based on principal component analysis. Optics Express. 18: 6461-76. PMID 20389670 DOI: 10.1364/Oe.18.006461  0.53
2010 Xu W, Xu F, Jones M, Keszthelyi B, Sedat J, Agard D, Mueller K. High-performance iterative electron tomography reconstruction with long-object compensation using graphics processing units (GPUs). Journal of Structural Biology. 171: 142-53. PMID 20371381 DOI: 10.1016/J.Jsb.2010.03.018  0.481
2010 Kner P, Sedat JW, Agard DA, Kam Z. High-resolution wide-field microscopy with adaptive optics for spherical aberration correction and motionless focusing. Journal of Microscopy. 237: 136-47. PMID 20096044 DOI: 10.1111/J.1365-2818.2009.03315.X  0.815
2010 Xu F, Xu W, Jones M, Keszthelyi B, Sedat J, Agard D, Mueller K. On the efficiency of iterative ordered subset reconstruction algorithms for acceleration on GPUs. Computer Methods and Programs in Biomedicine. 98: 261-70. PMID 19850372 DOI: 10.1016/J.Cmpb.2009.09.003  0.476
2010 Hanssen E, Carlton P, Deed S, Klonis N, Sedat J, DeRisi J, Tilley L. Whole cell imaging reveals novel modular features of the exomembrane system of the malaria parasite, Plasmodium falciparum. International Journal For Parasitology. 40: 123-34. PMID 19766648 DOI: 10.1016/J.Ijpara.2009.09.004  0.7
2009 Zheng SQ, Matsuda A, Braunfeld MB, Sedat JW, Agard DA. Dual-axis target mapping and automated sequential acquisition of dual-axis EM tomographic data. Journal of Structural Biology. 168: 323-31. PMID 19545637 DOI: 10.1016/J.Jsb.2009.06.010  0.492
2009 Hanssen E, Knoechel C, Carlton P, Sedat J, Larabell C, Tilley L. Whole cell imaging of plasmodium falciparum blood stages Microscopy and Microanalysis. 15: 866-867. DOI: 10.1017/S143192760909268X  0.672
2009 Sedat J, Agard D, Kam Z, Boulange J, Carlton P, Shao L, Kner P, Matsuda A. S09-04 OMX, a new microscope platform for increased time and spatial resolution Mechanisms of Development. 126: S36. DOI: 10.1016/J.Mod.2009.06.1036  0.766
2008 Wang X, Kam Z, Carlton PM, Xu L, Sedat JW, Blackburn EH. Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy. Epigenetics & Chromatin. 1: 4. PMID 19014413 DOI: 10.1186/1756-8935-1-4  0.752
2008 Schermelleh L, Carlton PM, Haase S, Shao L, Winoto L, Kner P, Burke B, Cardoso MC, Agard DA, Gustafsson MG, Leonhardt H, Sedat JW. Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science (New York, N.Y.). 320: 1332-6. PMID 18535242 DOI: 10.1126/Science.1156947  0.794
2008 Chang HH, Falick AM, Carlton PM, Sedat JW, DeRisi JL, Marletta MA. N-terminal processing of proteins exported by malaria parasites. Molecular and Biochemical Parasitology. 160: 107-15. PMID 18534695 DOI: 10.1016/J.Molbiopara.2008.04.011  0.64
2008 Pielage J, Cheng L, Fetter RD, Carlton PM, Sedat JW, Davis GW. A presynaptic giant ankyrin stabilizes the NMJ through regulation of presynaptic microtubules and transsynaptic cell adhesion. Neuron. 58: 195-209. PMID 18439405 DOI: 10.1016/J.Neuron.2008.02.017  0.657
2008 Gustafsson MG, Shao L, Carlton PM, Wang CJ, Golubovskaya IN, Cande WZ, Agard DA, Sedat JW. Three-dimensional resolution doubling in wide-field fluorescence microscopy by structured illumination. Biophysical Journal. 94: 4957-70. PMID 18326650 DOI: 10.1529/Biophysj.107.120345  0.801
2008 Shao L, Isaac B, Uzawa S, Agard DA, Sedat JW, Gustafsson MG. I5S: wide-field light microscopy with 100-nm-scale resolution in three dimensions. Biophysical Journal. 94: 4971-83. PMID 18326649 DOI: 10.1529/Biophysj.107.120352  0.8
2008 Kner P, Sedat J, Agard D, Kam Z. Applying adaptive optics to three-dimensional wide-field microscopy Proceedings of Spie - the International Society For Optical Engineering. 6888. DOI: 10.1117/12.773731  0.78
2008 Zheng SQ, Braunfeld MB, Sedat JW, Agard DA. Serial acquisition of dual axis EM tomographic data Microscopy and Microanalysis. 14: 1320-1321. DOI: 10.1017/S1431927608083530  0.474
2007 Hom EF, Marchis F, Lee TK, Haase S, Agard DA, Sedat JW. AIDA: an adaptive image deconvolution algorithm with application to multi-frame and three-dimensional data. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 24: 1580-600. PMID 17491626 DOI: 10.1364/Josaa.24.001580  0.792
2007 Kam Z, Kner P, Agard D, Sedat JW. Modelling the application of adaptive optics to wide-field microscope live imaging. Journal of Microscopy. 226: 33-42. PMID 17381707 DOI: 10.1111/J.1365-2818.2007.01751.X  0.805
2007 König P, Braunfeld MB, Sedat JW, Agard DA. The three-dimensional structure of in vitro reconstituted Xenopus laevis chromosomes by EM tomography. Chromosoma. 116: 349-72. PMID 17333236 DOI: 10.1007/S00412-007-0101-0  0.54
2007 Zheng SQ, Kollman JM, Braunfeld MB, Sedat JW, Agard DA. Automated acquisition of electron microscopic random conical tilt sets. Journal of Structural Biology. 157: 148-55. PMID 17169745 DOI: 10.1016/J.Jsb.2006.10.026  0.722
2007 Zheng SQ, Keszthelyi B, Branlund E, Lyle JM, Braunfeld MB, Sedat JW, Agard DA. UCSF tomography: an integrated software suite for real-time electron microscopic tomographic data collection, alignment, and reconstruction. Journal of Structural Biology. 157: 138-47. PMID 16904341 DOI: 10.1016/J.Jsb.2006.06.005  0.523
2007 Moss WC, Haase S, Lyle JM, Agard DA, Sedat JW. Reply to letter to the editor Journal of Microscopy. 225: 108. DOI: 10.1111/j.1365-2818.2007.01734.x  0.34
2006 Vazquez J, Müller M, Pirrotta V, Sedat JW. The Mcp element mediates stable long-range chromosome-chromosome interactions in Drosophila. Molecular Biology of the Cell. 17: 2158-65. PMID 16495335 DOI: 10.1091/Mbc.E06-01-0049  0.336
2006 Zheng SQ, Braunfeld MB, Keszthelyi B, Branlund E, Kollman JM, Sedat JW, Agard DA. Automated acquisition of tomographic and random conical tilt series and real-time reconstruction using UCSF tmography Microscopy and Microanalysis. 12: 88-89. DOI: 10.1017/S1431927606065871  0.677
2005 Moss WC, Haase S, Lyle JM, Agard DA, Sedat JW. A novel 3D wavelet-based filter for visualizing features in noisy biological data. Journal of Microscopy. 219: 43-9. PMID 16159339 DOI: 10.1111/J.1365-2818.2005.01492.X  0.491
2005 Harmon B, Sedat J. Cell-by-cell dissection of gene expression and chromosomal interactions reveals consequences of nuclear reorganization Plos Biology.. 3: e67. PMID 15737020 DOI: 10.1371/Journal.Pbio.0030067  0.785
2004 Lowenstein MG, Goddard TD, Sedat JW. Long-range interphase chromosome organization in Drosophila: a study using color barcoded fluorescence in situ hybridization and structural clustering analysis. Molecular Biology of the Cell. 15: 5678-92. PMID 15371546 DOI: 10.1091/Mbc.E04-04-0289  0.806
2004 Hanser BM, Gustafsson MG, Agard DA, Sedat JW. Phase-retrieved pupil functions in wide-field fluorescence microscopy. Journal of Microscopy. 216: 32-48. PMID 15369481 DOI: 10.1111/J.0022-2720.2004.01393.X  0.783
2004 Zheng QS, Braunfeld MB, Sedat JW, Agard DA. An improved strategy for automated electron microscopic tomography. Journal of Structural Biology. 147: 91-101. PMID 15193638 DOI: 10.1016/J.Jsb.2004.02.005  0.557
2004 Bailey B, Agard DA, Sedat JW, Barfels M, Chao H, Mooney PE. Performance evaluation of a transmission scintillator-based lens-coupled 4K CCD camera for use in low-dose electron cryo-microscopy Microscopy and Microanalysis. 10: 1204-1205. DOI: 10.1017/S1431927604886458  0.472
2004 Gustafsson MGL, Shao L, Agard DA, Sedat JW. Fluorescence microscopy without resolution limit Leos Summer Topical Meeting. 25-26.  0.485
2003 Hanser BM, Gustafsson MG, Agard DA, Sedat JW. Phase retrieval for high-numerical-aperture optical systems. Optics Letters. 28: 801-3. PMID 12779151 DOI: 10.1364/Ol.28.000801  0.782
2002 Vazquez J, Belmont AS, Sedat JW. The dynamics of homologous chromosome pairing during male Drosophila meiosis. Current Biology : Cb. 12: 1473-83. PMID 12225662 DOI: 10.1016/S0960-9822(02)01090-4  0.607
2002 Hanser BM, Gustafsson MGL, Agard DA, Sedat JW. Application of phase retrieved pupil functions in wide-field fluorescence microscopy Proceedings of Spie - the International Society For Optical Engineering. 4621: 40-46. DOI: 10.1117/12.467844  0.781
2001 Vazquez J, Belmont AS, Sedat JW. Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Current Biology : Cb. 11: 1227-39. PMID 11525737 DOI: 10.1016/S0960-9822(01)00390-6  0.605
2001 Marshall WF, Marko JF, Agard DA, Sedat JW. Chromosome elasticity and mitotic polar ejection force measured in living Drosophila embryos by four-dimensional microscopy-based motion analysis. Current Biology : Cb. 11: 569-78. PMID 11369201 DOI: 10.1016/S0960-9822(01)00180-4  0.66
2001 Grogan JL, Mohrs M, Harmon B, Lacy DA, Sedat JW, Locksley RM. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity. 14: 205-15. PMID 11290331 DOI: 10.1016/S1074-7613(01)00103-0  0.756
2001 Kam Z, Hanser B, Gustafsson MG, Agard DA, Sedat JW. Computational adaptive optics for live three-dimensional biological imaging. Proceedings of the National Academy of Sciences of the United States of America. 98: 3790-5. PMID 11274396 DOI: 10.1073/Pnas.071275698  0.8
2001 Hanser BM, Gustafsson MGL, Agard DA, Sedat JW. Phase retrieval of widefield microscopy point spread functions Proceedings of Spie - the International Society For Optical Engineering. 4261: 60-68. DOI: 10.1117/12.424520  0.761
2000 Bass HW, Riera-Lizarazu O, Ananiev EV, Bordoli SJ, Rines HW, Phillips RL, Sedat JW, Agard DA, Cande WZ. Evidence for the coincident initiation of homolog pairing and synapsis during the telomere-clustering (bouquet) stage of meiotic prophase. Journal of Cell Science. 113: 1033-42. PMID 10683151  0.678
2000 Servant G, Weiner OD, Herzmark P, Balla T, Sedat JW, Bourne HR. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science (New York, N.Y.). 287: 1037-40. PMID 10669415 DOI: 10.1126/Science.287.5455.1037  0.689
2000 Gustafsson MGL, Agard DA, Sedat JW. Doubling the lateral resolution of wide-field fluorescence microscopy using structured illumination Proceedings of Spie - the International Society For Optical Engineering. 3919: 141-150.  0.769
1999 Kalman D, Weiner OD, Goosney DL, Sedat JW, Finlay BB, Abo A, Bishop JM. Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals. Nature Cell Biology. 1: 389-91. PMID 10559969 DOI: 10.1038/14087  0.589
1999 Weiner OD, Servant G, Welch MD, Mitchison TJ, Sedat JW, Bourne HR. Spatial control of actin polymerization during neutrophil chemotaxis. Nature Cell Biology. 1: 75-81. PMID 10559877 DOI: 10.1038/10042  0.723
1999 Gustafsson MG, Agard DA, Sedat JW. I5M: 3D widefield light microscopy with better than 100 nm axial resolution. Journal of Microscopy. 195: 10-6. PMID 10444297 DOI: 10.1046/J.1365-2818.1999.00576.X  0.545
1999 Marshall WF, Sedat JW. Nuclear architecture. Results and Problems in Cell Differentiation. 25: 283-301. PMID 10339752  0.423
1999 Servant G, Weiner OD, Neptune ER, Sedat JW, Bourne HR. Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis. Molecular Biology of the Cell. 10: 1163-78. PMID 10198064 DOI: 10.1091/Mbc.10.4.1163  0.692
1998 Straight AF, Sedat JW, Murray AW. Time-lapse microscopy reveals unique roles for kinesins during anaphase in budding yeast. The Journal of Cell Biology. 143: 687-94. PMID 9813090 DOI: 10.1083/Jcb.143.3.687  0.672
1998 Fung JC, Marshall WF, Dernburg A, Agard DA, Sedat JW. Homologous chromosome pairing in Drosophila melanogaster proceeds through multiple independent initiations. The Journal of Cell Biology. 141: 5-20. PMID 9531544 DOI: 10.1083/Jcb.141.1.5  0.664
1998 Dernburg AF, Sedat JW. Mapping three-dimensional chromosome architecture in situ. Methods in Cell Biology. 53: 187-233. PMID 9348510 DOI: 10.1016/S0091-679X(08)60880-8  0.4
1997 Han KF, Sedat JW, Agard DA. Practical image restoration of thick biological specimens using multiple focus levels in transmission electron microscopy. Journal of Structural Biology. 120: 237-44. PMID 9441929 DOI: 10.1006/Jsbi.1997.3914  0.565
1997 Marshall WF, Straight A, Marko JF, Swedlow J, Dernburg A, Belmont A, Murray AW, Agard DA, Sedat JW. Interphase chromosomes undergo constrained diffusional motion in living cells. Current Biology : Cb. 7: 930-9. PMID 9382846 DOI: 10.1016/S0960-9822(06)00412-X  0.798
1997 Oegema K, Marshall WF, Sedat JW, Alberts BM. Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190. Journal of Cell Science. 110: 1573-83. PMID 9247191  0.504
1997 Nunnari J, Marshall WF, Straight A, Murray A, Sedat JW, Walter P. Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA. Molecular Biology of the Cell. 8: 1233-42. PMID 9243504 DOI: 10.1091/Mbc.8.7.1233  0.725
1997 Straight AF, Marshall WF, Sedat JW, Murray AW. Mitosis in living budding yeast: anaphase A but no metaphase plate. Science (New York, N.Y.). 277: 574-8. PMID 9228009 DOI: 10.1126/Science.277.5325.574  0.759
1997 Marshall WF, Fung JC, Sedat JW. Deconstructing the nucleus: global architecture from local interactions. Current Opinion in Genetics & Development. 7: 259-63. PMID 9115425 DOI: 10.1016/S0959-437X(97)80136-0  0.528
1997 Bass HW, Marshall WF, Sedat JW, Agard DA, Cande WZ. Telomeres cluster de novo before the initiation of synapsis: a three-dimensional spatial analysis of telomere positions before and during meiotic prophase. The Journal of Cell Biology. 137: 5-18. PMID 9105032 DOI: 10.1083/Jcb.137.1.5  0.795
1997 Kirk KE, Harmon BP, Reichardt IK, Sedat JW, Blackburn EH. Block in anaphase chromosome separation caused by a telomerase template mutation. Science (New York, N.Y.). 275: 1478-81. PMID 9045613 DOI: 10.1126/Science.275.5305.1478  0.784
1997 Fung JC, Kane L, Smith SD, Sedat JW, Agard DA, Spontak RJ. Phase behavior of complex diblock copolymer blends: A transmission electron microscopy study Materials Science Forum. 239: 179-184. DOI: 10.4028/Www.Scientific.Net/Msf.239-241.179  0.476
1997 Laurer JH, Hajduk DA, Fung JC, Sedat JW, Smith SD, Gruner SM, Agard DA, Spontak RJ. Microstructural analysis of a cubic bicontinuous morphology in a neat SIS triblock copolymer Macromolecules. 30: 3938-3941. DOI: 10.1021/Ma970449L  0.429
1997 Laurer JH, Fung JC, Sedat JW, Smith SD, Samseth J, Mortensen K, Agard DA, Spontak RJ. From micelles to randomly connected, bilayered membranes in dilute block copolymer blends Langmuir. 13: 2177-2180. DOI: 10.1021/La9608876  0.495
1997 Agard DA, Braunfeld MB, Chen H, McQuitty R, Sedat J. Approaches for High Resolution Cryo-Electron Tomography of Biological Specimens Microscopy and Microanalysis. 3: 1111-1112. DOI: 10.1017/S1431927600012447  0.498
1997 Gustafsson MGL, Agard DA, Sedat JW. Sub-100nm Axial Resolution in 3D Widefield Optical Microscopy Using Two Opposing Objective Lenses Microscopy and Microanalysis. 3: 801-802. DOI: 10.1017/S1431927600010898  0.511
1997 Agard DA, Guenbaut V, Moritz M, Braunfeld MB, Zhang G, Sedat JW. Structure of Centrosomes and Chromosomes Through IVEM Tomography Microscopy and Microanalysis. 3: 223-224. DOI: 10.1017/S143192760000800X  0.535
1997 Sedat J, Marshall W, Dernburg A, Fung J, Agard D. New Insights Into the Three-Dimensional Structure of the Nucleus and Chromosomes Microscopy and Microanalysis. 3: 213-214. DOI: 10.1017/S1431927600007959  0.543
1997 Hiraoka Y, Agard DA, Sedat JW. Spatial arrangement of homologous chromosomes during anaphase in early embryos of Drosophila melanogaster studied by three-dimensional fluorescence microscopy Bioimaging. 5: 183-193. DOI: 10.1002/1361-6374(199712)5:4<183::Aid-Bio2>3.3.Co;2-1  0.583
1997 Kam Z, Agard DA, Sedat JW. Three-dimensional microscopy in thick biological samples: A fresh approach for adjusting focus and correcting spherical aberration Bioimaging. 5: 40-49. DOI: 10.1002/1361-6374(199703)5:1<40::Aid-Bio4>3.3.Co;2-N  0.567
1996 Paddy MR, Saumweber H, Agard DA, Sedat JW. Time-resolved, in vivo studies of mitotic spindle formation and nuclear lamina breakdown in Drosophila early embryos. Journal of Cell Science. 109: 591-607. PMID 8907705  0.521
1996 Han KF, Gubbens AJ, Sedat JW, Agard DA. Optimal strategies for imaging thick biological specimens: exit wavefront reconstruction and energy-filtered imaging. Journal of Microscopy. 183: 124-32. PMID 8805824 DOI: 10.1046/J.1365-2818.1996.810640.X  0.544
1996 Marshall WF, Dernburg AF, Harmon B, Agard DA, Sedat JW. Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster. Molecular Biology of the Cell. 7: 825-42. PMID 8744953 DOI: 10.1091/Mbc.7.5.825  0.789
1996 Fung JC, Liu W, de Ruijter WJ, Chen H, Abbey CK, Sedat JW, Agard DA. Toward fully automated high-resolution electron tomography. Journal of Structural Biology. 116: 181-9. PMID 8742742 DOI: 10.1006/Jsbi.1996.0029  0.498
1996 Chen H, Hughes DD, Chan TA, Sedat JW, Agard DA. IVE (Image Visualization Environment): a software platform for all three-dimensional microscopy applications. Journal of Structural Biology. 116: 56-60. PMID 8742723 DOI: 10.1006/Jsbi.1996.0010  0.494
1996 Dernburg AF, Sedat JW, Hawley RS. Direct evidence of a role for heterochromatin in meiotic chromosome segregation. Cell. 86: 135-46. PMID 8689681 DOI: 10.1016/S0092-8674(00)80084-7  0.353
1996 Dernburg AF, Broman KW, Fung JC, Marshall WF, Philips J, Agard DA, Sedat JW. Perturbation of nuclear architecture by long-distance chromosome interactions. Cell. 85: 745-59. PMID 8646782 DOI: 10.1016/S0092-8674(00)81240-4  0.657
1996 Scalettar BA, Swedlow JR, Sedat JW, Agard DA. Dispersion, aberration and deconvolution in multi-wavelength fluorescence images. Journal of Microscopy. 182: 50-60. PMID 8632447 DOI: 10.1046/J.1365-2818.1996.122402.X  0.59
1996 Spontak RJ, Fung JC, Braunfeld MB, Sedat JW, Agard DA, Ashraf A, Smith SD. Architecture-induced phase immiscibility in a diblock/multiblock copolymer blend Macromolecules. 29: 2850-2856. DOI: 10.1021/Ma9515691  0.464
1996 Spontak RJ, Fung JC, Braunfeld MB, Sedat JW, Agard DA, Kane L, Smith SD, Satkowski MM, Ashraf A, Hajduk DA, Grüner SM. Phase behavior of ordered diblock copolymer blends: Effect of compositional heterogeneity Macromolecules. 29: 4494-4507. DOI: 10.1021/Ma9515689  0.488
1996 Marshall WF, Agard DA, Sedat JW. Chromosome mechanics in vivo: quantitative analysis of nonrigid 3D chromosome motion in Drosophila embryos Proceedings of Spie - the International Society For Optical Engineering. 2678: 142-150.  0.621
1996 Gustafsson MG, Agard DA, Sedat JW. 3D widefield microscopy with two objective lenses: experimental verification of improved axial resolution Proceedings of Spie - the International Society For Optical Engineering. 2655: 62-66.  0.747
1995 Moritz M, Braunfeld MB, Sedat JW, Alberts B, Agard DA. Microtubule nucleation by gamma-tubulin-containing rings in the centrosome. Nature. 378: 638-40. PMID 8524401 DOI: 10.1038/378638A0  0.501
1995 Han KF, Sedat JW, Agard DA. Mechanism of image formation for thick biological specimens: exit wavefront reconstruction and electron energy-loss spectroscopic imaging. Journal of Microscopy. 178: 107-19. PMID 7783184 DOI: 10.1111/J.1365-2818.1995.Tb03586.X  0.551
1995 Moritz M, Braunfeld MB, Fung JC, Sedat JW, Alberts BM, Agard DA. Three-dimensional structural characterization of centrosomes from early Drosophila embryos. The Journal of Cell Biology. 130: 1149-59. PMID 7657699 DOI: 10.1083/Jcb.130.5.1149  0.523
1995 Urata Y, Parmelee SJ, Agard DA, Sedat JW. A three-dimensional structural dissection of Drosophila polytene chromosomes. The Journal of Cell Biology. 131: 279-95. PMID 7593159 DOI: 10.1083/Jcb.131.2.279  0.535
1995 Dernburg AF, Sedat JW, Cande WZ, Bass HW. 11 Cytology of Telomeres Cold Spring Harbor Monograph Archive. 29: 295-338. DOI: 10.1101/087969457.29.295  0.689
1995 Marshall WF, Agard DA, Sedat JW. Quantitative analysis of chromosome motion in Drosophila melanogaster Proceedings of Spie - the International Society For Optical Engineering. 2412: 33-42.  0.602
1995 Gustafsson MG, Agard DA, Sedat JW. Sevenfold improvement of axial resolution in 3D wide-field microscopy using two objective-lenses Proceedings of Spie - the International Society For Optical Engineering. 2412: 147-156.  0.75
1994 Horowitz RA, Agard DA, Sedat JW, Woodcock CL. The three-dimensional architecture of chromatin in situ: electron tomography reveals fibers composed of a continuously variable zig-zag nucleosomal ribbon. The Journal of Cell Biology. 125: 1-10. PMID 8138564 DOI: 10.1083/Jcb.125.1.1  0.435
1994 Dawe RK, Sedat JW, Agard DA, Cande WZ. Meiotic chromosome pairing in maize is associated with a novel chromatin organization. Cell. 76: 901-12. PMID 8124724 DOI: 10.1016/0092-8674(94)90364-6  0.693
1994 Braunfeld MB, Koster AJ, Sedat JW, Agard DA. Cryo automated electron tomography: towards high-resolution reconstructions of plastic-embedded structures. Journal of Microscopy. 174: 75-84. PMID 8051698 DOI: 10.1111/J.1365-2818.1994.Tb03451.X  0.498
1994 Braunfeld MB, Moritz M, Alberts BM, Sedat JW, Agard DA. Three-dimensional reconstruction of isolated centrosomes by automated electron tomography Proceedings - Annual Meeting, Microscopy Society of America. 310-311.  0.417
1993 Hiraoka Y, Dernburg AF, Parmelee SJ, Rykowski MC, Agard DA, Sedat JW. The onset of homologous chromosome pairing during Drosophila melanogaster embryogenesis. The Journal of Cell Biology. 120: 591-600. PMID 8425892 DOI: 10.1083/Jcb.120.3.591  0.565
1993 Swedlow JR, Sedat JW, Agard DA. Multiple chromosomal populations of topoisomerase II detected in vivo by time-lapse, three-dimensional wide-field microscopy. Cell. 73: 97-108. PMID 8384932 DOI: 10.1016/0092-8674(93)90163-K  0.547
1993 Swedlow JR, Agard DA, Sedat JW. Chromosome structure inside the nucleus. Current Opinion in Cell Biology. 5: 412-6. PMID 8352957 DOI: 10.1016/0955-0674(93)90005-B  0.549
1993 Kam Z, Jones MO, Chen H, Agard DA, Sedat JW. Design and construction of an optimal illumination system for quantitative wide‐field multi‐dimensional microscopy Bioimaging. 1: 71-81. DOI: 10.1002/1361-6374(199306)1:2<71::Aid-Bio2>3.3.Co;2-R  0.462
1993 Braunfeld MB, Koster AJ, Sedat JW, Agard DA. Properties and dose dependence of embedding media for cryo-automated electron tomography Proceedings - Annual Meeting, Microscopy Society of America. 436-437.  0.395
1993 Koster AJ, Chen H, Clyborne W, Sedat JW, Agard DA. Design and performance of instrumentation for automated single-tilt-axis electron tomography Proceedings - Annual Meeting, Microscopy Society of America. 448-449.  0.4
1992 Koster AJ, Chen H, Sedat JW, Agard DA. Automated microscopy for electron tomography. Ultramicroscopy. 46: 207-27. PMID 1481272 DOI: 10.1016/0304-3991(92)90016-D  0.526
1992 Paddy MR, Agard DA, Sedat JW. An extended view of nuclear lamin structure, function, and dynamics. Seminars in Cell Biology. 3: 255-66. PMID 1421171 DOI: 10.1016/1043-4682(92)90027-S  0.497
1991 Kam Z, Minden JS, Agard DA, Sedat JW, Leptin M. Drosophila gastrulation: analysis of cell shape changes in living embryos by three-dimensional fluorescence microscopy. Development (Cambridge, England). 112: 365-70. PMID 1794308  0.454
1991 Hiraoka Y, Swedlow JR, Paddy MR, Agard DA, Sedat JW. Three-dimensional multiple-wavelength fluorescence microscopy for the structural analysis of biological phenomena. Seminars in Cell Biology. 2: 153-65. PMID 1720334  0.566
1991 HIRAOKA Y, CHEN H, SEDAT JW, AGARD DA. Three-dimensional fluorescence microscopy for the analysis of spatial arrangement of chromosomes. Acta Histochemica Et Cytochemica. 24: 357-365. DOI: 10.1267/Ahc.24.357  0.599
1991 Paddy MR, Swedlow JR, Hiraoka Y, Sedat JW, Agard DA. Time-resolved, multi-wavelength 3-D fluorescence microscopy of nuclear structures Scanning. 13: I2.  0.477
1990 Hiraoka Y, Sedat JW, Agard DA. Determination of three-dimensional imaging properties of a light microscope system. Partial confocal behavior in epifluorescence microscopy. Biophysical Journal. 57: 325-33. PMID 2317554 DOI: 10.1016/S0006-3495(90)82534-0  0.576
1990 Paddy MR, Belmont AS, Saumweber H, Agard DA, Sedat JW. Interphase nuclear envelope lamins form a discontinuous network that interacts with only a fraction of the chromatin in the nuclear periphery. Cell. 62: 89-106. PMID 2194675 DOI: 10.1016/0092-8674(90)90243-8  0.669
1990 Hiraoka Y, Agard DA, Sedat JW. Temporal and spatial coordination of chromosome movement, spindle formation, and nuclear envelope breakdown during prometaphase in Drosophila melanogaster embryos. The Journal of Cell Biology. 111: 2815-28. PMID 2125300 DOI: 10.1083/Jcb.111.6.2815  0.58
1990 Koshy M, Agard DA, Sedat JW. Solution of Toeplitz systems for the restoration of 3-D optical sectioning microscopy data Proceedings of Spie - the International Society For Optical Engineering. 1205: 64-71.  0.42
1989 Aikens RS, Agard DA, Sedat JW. Solid-state imagers for microscopy. Methods in Cell Biology. 29: 291-313. PMID 2643764 DOI: 10.1016/S0091-679X(08)60199-5  0.536
1989 Hiraoka Y, Minden JS, Swedlow JR, Sedat JW, Agard DA. Focal points for chromosome condensation and decondensation revealed by three-dimensional in vivo time-lapse microscopy. Nature. 342: 293-6. PMID 2509947 DOI: 10.1038/342293A0  0.581
1989 Minden JS, Agard DA, Sedat JW, Alberts BM. Direct cell lineage analysis in Drosophila melanogaster by time-lapse, three-dimensional optical microscopy of living embryos. The Journal of Cell Biology. 109: 505-16. PMID 2503522 DOI: 10.1083/Jcb.109.2.505  0.543
1989 Shaw PJ, Agard DA, Hiraoka Y, Sedat JW. Tilted view reconstruction in optical microscopy. Three-dimensional reconstruction of Drosophila melanogaster embryo nuclei. Biophysical Journal. 55: 101-10. PMID 2495031 DOI: 10.1016/S0006-3495(89)82783-3  0.513
1989 Agard DA, Hiraoka Y, Shaw P, Sedat JW. Fluorescence microscopy in three dimensions. Methods in Cell Biology. 30: 353-77. PMID 2494418 DOI: 10.1016/S0091-679X(08)60986-3  0.591
1989 Belmont AS, Braunfeld MB, Sedat JW, Agard DA. Large-scale chromatin structural domains within mitotic and interphase chromosomes in vivo and in vitro. Chromosoma. 98: 129-43. PMID 2476279 DOI: 10.1007/Bf00291049  0.692
1989 Chen H, Sedat JW, Agard DA. Software and hardware for 3-d gray level image analysis and quantization Proceedings of Spie - the International Society For Optical Engineering. 1161: 31-41. DOI: 10.1117/12.962685  0.445
1989 Agard DA, Hiraoka Y, Sedat JW. Three-dimensional microscopy: Image processing for high resolution subcellular imaging Proceedings of Spie - the International Society For Optical Engineering. 1161: 24-30. DOI: 10.1117/12.962684  0.5
1989 Agard DA, Hiraoka Y, Shaw P, Sedat JW. Chapter 13 Fluorescence Microscopy in Three Dimensions Methods in Cell Biology. 30: 353-374,374a,375-377. DOI: 10.1016/S0091-679X(08)60986-3  0.457
1989 Agard D, Belmont A, Hiroka Y, Paddy M, Sedat J. Structure and function relationships—The diploid nucleus of Cell Differentiation and Development. 27: 107. DOI: 10.1016/0922-3371(89)90339-0  0.644
1988 Agard DA, Hiraoka Y, Sedat JW. Three-dimensional light microscopy of diploid Drosophila chromosomes. Cell Motility and the Cytoskeleton. 10: 18-27. PMID 3141069 DOI: 10.1002/Cm.970100106  0.609
1988 Rykowski MC, Parmelee SJ, Agard DA, Sedat JW. Precise determination of the molecular limits of a polytene chromosome band: regulatory sequences for the Notch gene are in the interband. Cell. 54: 461-72. PMID 3135939 DOI: 10.1016/0092-8674(88)90067-0  0.547
1988 Gruenbaum Y, Landesman Y, Drees B, Bare JW, Saumweber H, Paddy MR, Sedat JW, Smith DE, Benton BM, Fisher PA. Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene. The Journal of Cell Biology. 106: 585-96. PMID 3126192 DOI: 10.1083/Jcb.106.3.585  0.3
1987 Hiraoka Y, Sedat JW, Agard DA. The use of a charge-coupled device for quantitative optical microscopy of biological structures. Science (New York, N.Y.). 238: 36-41. PMID 3116667 DOI: 10.1126/Science.3116667  0.593
1987 Belmont AS, Sedat JW, Agard DA. A three-dimensional approach to mitotic chromosome structure: evidence for a complex hierarchical organization. The Journal of Cell Biology. 105: 77-92. PMID 3112167 DOI: 10.1083/Jcb.105.1.77  0.67
1987 Hochstrasser M, Sedat JW. Three-dimensional organization of Drosophila melanogaster interphase nuclei. II. Chromosome spatial organization and gene regulation. The Journal of Cell Biology. 104: 1471-83. PMID 3108265 DOI: 10.1083/Jcb.104.6.1471  0.612
1987 Hochstrasser M, Sedat JW. Three-dimensional organization of Drosophila melanogaster interphase nuclei. I. Tissue-specific aspects of polytene nuclear architecture. The Journal of Cell Biology. 104: 1455-70. PMID 3108264 DOI: 10.1083/Jcb.104.6.1455  0.608
1986 Hochstrasser M, Mathog D, Gruenbaum Y, Saumweber H, Sedat JW. Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster. The Journal of Cell Biology. 102: 112-23. PMID 3079766 DOI: 10.1083/Jcb.102.1.112  0.615
1985 Mathog D, Hochstrasser M, Sedat JW. Light microscope based analysis of three-dimensional structure: applications to the study of Drosophila salivary gland nuclei. I. Data collection and analysis. Journal of Microscopy. 137: 241-52. PMID 3999131 DOI: 10.1111/J.1365-2818.1985.Tb02582.X  0.607
1984 Gruenbaum Y, Hochstrasser M, Mathog D, Saumweber H, Agard DA, Sedat JW. Spatial organization of the Drosophila nucleus: a three-dimensional cytogenetic study. Journal of Cell Science. Supplement. 1: 223-34. PMID 6442295 DOI: 10.1242/Jcs.1984.Supplement_1.14  0.713
1984 Mathog D, Hochstrasser M, Gruenbaum Y, Saumweber H, Sedat J. Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei. Nature. 308: 414-21. PMID 6424026 DOI: 10.1038/308414A0  0.627
1983 Agard DA, Sedat JW. Three-dimensional architecture of a polytene nucleus. Nature. 302: 676-81. PMID 6403872 DOI: 10.1038/302676A0  0.599
1983 Mitchison TJ, Sedat J. Localization of antigenic determinants in whole Drosophila embryos. Developmental Biology. 99: 261-4. PMID 6194030 DOI: 10.1016/0012-1606(83)90275-0  0.475
1982 Giloh H, Sedat JW. Fluorescence microscopy: reduced photobleaching of rhodamine and fluorescein protein conjugates by n-propyl gallate. Science (New York, N.Y.). 217: 1252-5. PMID 7112126 DOI: 10.1126/Science.7112126  0.345
1980 Agard DA, Sedat JW. Three-dimensional analysis of biological specimens utilizing image processing techniques Proceedings of Spie - the International Society For Optical Engineering. 264: 110-117. DOI: 10.1117/12.959792  0.468
1976 Air GM, Blackburn EH, Coulson AR, Galibert F, Sanger F, Sedat JW, Ziff EB. Gene F of bacteriophage phiX174. Correlation of nucleotide sequences from the DNA and amino acid sequences from the gene product. Journal of Molecular Biology. 107: 445-58. PMID 1088826 DOI: 10.1016/S0022-2836(76)80077-0  0.747
1976 Sedat J, Ziff E, Galibert F. Direct determination of DNA nucleotide sequences. Structure of large specific fragments of bacteriophage phiX174 DNA. Journal of Molecular Biology. 107: 391-416. PMID 1003475 DOI: 10.1016/S0022-2836(76)80074-5  0.466
1976 Kamen R, Sedat J, Ziff E. Orientation of the Complementary Strands of Polyoma Virus DNA with Respect to the DNA Physical Map Journal of Virology. 17: 212-218. DOI: 10.1128/jvi.17.1.212-218.1976  0.457
1974 Galibert F, Sedat J, Ziff E. Direct determination of DNA nucleotide sequences: structure of a fragment of bacteriophage phiX172 DNA. Journal of Molecular Biology. 87: 377-407. PMID 4374546 DOI: 10.1016/0022-2836(74)90093-X  0.462
1973 Razin A, Sedat JW, Sinsheimer RL. In vivo methylation of replicating bacteriophage phi chi174 DNA. Journal of Molecular Biology. 78: 417-25. PMID 4585324 DOI: 10.1016/0022-2836(73)90465-8  0.445
1973 Ziff EB, Sedat JW, Galibert F. Determination of the nucleotide sequence of a fragment of bacteriophage phiX 174 DNA. Nature: New Biology. 241: 34-7. PMID 4349156  0.449
1970 Razin A, Sedat JW, Sinsheimer RL. Structure of the DNA of bacteriophage phiX174. VII. Methylation. Journal of Molecular Biology. 53: 251-9. PMID 5493279 DOI: 10.1016/0022-2836(70)90298-6  0.429
1970 Sedat JW, Sinsheimer RL. The in vivo  X mRNA Cold Spring Harbor Symposia On Quantitative Biology. 35: 163-170. DOI: 10.1101/Sqb.1970.035.01.023  0.426
1969 Sedat J, Lyon A, Sinsheimer RL. Purification of Escherichia coli pulse-labeled RNA by benzoylated DEAE-cellulose chromatography. Journal of Molecular Biology. 44: 415-34. PMID 5346049 DOI: 10.1016/0022-2836(69)90370-2  0.421
1967 Sedat JW, Kelly RB, Sinsheimer RL. Fractionation of nucleic acid on benzoylated-naphthoylated DEAE cellulose. Journal of Molecular Biology. 26: 537-40. PMID 5339798 DOI: 10.1016/0022-2836(67)90321-X  0.571
1964 SEDAT J, SINSHEIMER RL. STRUCTURE OF THE DNA OF BACTERIOPHAGE PHI-X174. V. PURINE SEQUENCES Journal of Molecular Biology. 9: 489-497. PMID 14202280 DOI: 10.1016/S0022-2836(64)80221-7  0.454
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