Timothy Mitchell - Publications

2011 Stanford University School of Medicine, Palo Alto, CA, United States 

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shephard AM, Mitchell TS, Snell-Rood EC. Monarch caterpillars are robust to combined exposure to the roadside micronutrients sodium and zinc. Conservation Physiology. 9: coab061. PMID 34386239 DOI: 10.1093/conphys/coab061  1
2021 Lokken EM, Taylor GG, Huebner EM, Vanderhoeven J, Hendrickson S, Coler B, Sheng JS, Walker CL, McCartney SA, Kretzer NM, Resnick R, Kachikis A, Barnhart N, Schulte V, Bergam B, ... ... Mitchell T, et al. Higher SARS-CoV-2 Infection Rate in Pregnant Patients. American Journal of Obstetrics and Gynecology. PMID 33607103 DOI: 10.1016/j.ajog.2021.02.011  1
2021 Lokken EM, Huebner EM, Taylor GG, Hendrickson S, Vanderhoeven J, Kachikis A, Coler B, Walker CL, Sheng JS, Al-Haddad BJS, McCartney SA, Kretzer NM, Resnick R, Barnhart N, Schulte V, ... ... Mitchell T, et al. Disease Severity, Pregnancy Outcomes and Maternal Deaths among Pregnant Patients with SARS-CoV-2 Infection in Washington State. American Journal of Obstetrics and Gynecology. PMID 33515516 DOI: 10.1016/j.ajog.2020.12.1221  1
2020 Kennedy WR, DeWees TA, Acharya S, Mahmood M, Knutson NC, Goddu SM, Kavanaugh JA, Mitchell TJ, Rich KM, Kim AH, Leuthardt EC, Dowling JL, Dunn GP, Chicoine MR, Perkins SM, et al. Internal dose escalation associated with increased local control for melanoma brain metastases treated with stereotactic radiosurgery. Journal of Neurosurgery. 1-7. PMID 33307528 DOI: 10.3171/2020.7.JNS192210  1
2020 Maraghechi B, Kim T, Mitchell TJ, Goddu SM, Dise J, Kavanaugh JA, Zoberi JE, Mutic S, Knutson NC. Filmless quality assurance of a Leksell Gamma Knife® Icon™. Journal of Applied Clinical Medical Physics. PMID 33300664 DOI: 10.1002/acm2.13070  0.12
2020 Badgujar DC, Anil A, Green AE, Surve MV, Madhavan S, Beckett A, Prior IA, Godsora BK, Patil SB, More PK, Sarkar SG, Mitchell A, Banerjee R, Phale PS, Mitchell TJ, et al. Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle. Plos Pathogens. 16: e1009016. PMID 33216805 DOI: 10.1371/journal.ppat.1009016  1
2020 Nerlich A, von Wunsch Teruel I, Mieth M, Hönzke K, Rückert JC, Mitchell TJ, Suttorp N, Hippenstiel S, Hocke AC. Reversion of pneumolysin induced executioner caspase activation redirects cells to survival. The Journal of Infectious Diseases. PMID 33045080 DOI: 10.1093/infdis/jiaa639  1
2020 Watson K, Russell CD, Baillie JK, Dhaliwal K, Fitzgerald JR, Mitchell TJ, Simpson AJ, Renshaw SA, Dockrell DH. Developing Novel Host-Based Therapies Targeting Microbicidal Responses in Macrophages and Neutrophils to Combat Bacterial Antimicrobial Resistance. Frontiers in Immunology. 11: 786. PMID 32582139 DOI: 10.3389/fimmu.2020.00786  1
2020 Mitchell TS, Agnew L, Meyer R, Sikkink KL, Oberhauser KS, Borer ET, Snell-Rood EC. Traffic influences nutritional quality of roadside plants for monarch caterpillars. The Science of the Total Environment. 724: 138045. PMID 32408428 DOI: 10.1016/J.Scitotenv.2020.138045  0.01
2020 Hall JM, Mitchell TS, Thawley CJ, Stroud JT, Warner DA. Adaptive seasonal shift towards investment in fewer, larger offspring: Evidence from field and laboratory studies. The Journal of Animal Ecology. PMID 31994721 DOI: 10.1111/1365-2656.13182  1
2020 Mitchell T, Seitzman B, Ballard N, Petersen SE, Shimony J, Leuthardt E. Human brain functional network organization is disrupted following whole-brain radiation therapy. Brain Connectivity. PMID 31964163 DOI: 10.1089/Brain.2019.0713  0.01
2020 Prusator MT, Zhao T, Kavanaugh JA, Santanam L, Dise J, Goddu SM, Mitchell TJ, Zoberi JE, Kim T, Mutic S, Knutson NC. Evaluation of a new secondary dose calculation software for Gamma Knife radiosurgery. Journal of Applied Clinical Medical Physics. 21: 95-102. PMID 31943756 DOI: 10.1002/Acm2.12794  0.04
2020 Warner DA, Mitchell TS, Bodensteiner BL, Janzen FJ. Sex and Incubation Temperature Independently Affect Embryonic Development and Offspring Size in a Turtle with Temperature-Dependent Sex Determination. Physiological and Biochemical Zoology : Pbz. 93: 62-74. PMID 31808735 DOI: 10.1086/706786  1
2019 Fanter CE, Lin Z, Keenan SW, Janzen FJ, Mitchell TS, Warren DE. Development-specific transcriptomic profiling suggests new mechanisms for anoxic survival in the ventricle of overwintering turtles. The Journal of Experimental Biology. PMID 31862849 DOI: 10.1242/Jeb.213918  1
2019 Hupp S, Grandgirard D, Mitchell TJ, Leib SL, Hathaway LJ, Iliev AI. Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia. Journal of Neuroinflammation. 16: 105. PMID 31103037 DOI: 10.1186/s12974-019-1491-7  0.01
2019 Knutson NC, Hawkins BJ, Bollinger D, Goddu SM, Kavanaugh JA, Santanam L, Mitchell TJ, Zoberi JE, Tsien C, Huang J, Robinson CG, Perkins SM, Dowling JL, Chicoine MR, Rich KM, et al. Characterization and validation of an intra-fraction motion management system for masked-based radiosurgery. Journal of Applied Clinical Medical Physics. PMID 31055877 DOI: 10.1002/Acm2.12573  0.2
2019 Janzen FJ, Delaney DM, Mitchell TS, Warner DA. Do covariances between maternal behavior and embryonic physiology drive sex-ratio evolution under environmental sex determination? The Journal of Heredity. PMID 30982894 DOI: 10.1093/jhered/esz021  1
2019 Bodensteiner BL, Warner DA, Iverson JB, Milne-Zelman CL, Mitchell TS, Refsnider JM, Janzen FJ. Geographic variation in thermal sensitivity of early life traits in a widespread reptile. Ecology and Evolution. 9: 2791-2802. PMID 30891217 DOI: 10.1002/ece3.4956  1
2019 Preston JA, Bewley MA, Marriott HM, Houghton AM, Mohasin M, Jubrail J, Morris L, Stephenson YL, Cross S, Greaves DR, Craig RW, van Rooijen N, Bingle CD, Read RC, Mitchell TJ, et al. Alveolar Macrophage Apoptosis-Associated Bacterial Killing Helps Prevent Murine Pneumonia. American Journal of Respiratory and Critical Care Medicine. PMID 30649895 DOI: 10.1164/Rccm.201804-0646Oc  1
2019 Li C, Bademci G, Subasioglu A, Diaz-Horta O, Zhu Y, Liu J, Mitchell TG, Abad C, Seyhan S, Duman D, Cengiz FB, Tokgoz-Yilmaz S, Blanton SH, Farooq A, Walz K, et al. Dysfunction of , encoding the GRB2-related adaptor protein, is linked to sensorineural hearing loss. Proceedings of the National Academy of Sciences of the United States of America. PMID 30610177 DOI: 10.1073/Pnas.1810951116  0.01
2018 Maurer J, Hupp S, Pillich H, Mitchell TJ, Chakraborty T, Iliev AI. Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O. Scientific Reports. 8: 15846. PMID 30367146 DOI: 10.1038/s41598-018-34031-4  0.01
2018 Köffel R, Wolfmeier H, Larpin Y, Besançon H, Schoenauer R, Babiychuk VS, Drücker P, Pabst T, Mitchell TJ, Babiychuk EB, Draeger A. Host-Derived Microvesicles Carrying Bacterial Pore-Forming Toxins Deliver Signals to Macrophages: A Novel Mechanism of Shaping Immune Responses. Frontiers in Immunology. 9: 1688. PMID 30100903 DOI: 10.3389/fimmu.2018.01688  1
2018 Mitchell TS, Janzen FJ, Warner DA. Quantifying the effects of embryonic phenotypic plasticity on adult phenotypes in reptiles: A review of current knowledge and major gaps. Journal of Experimental Zoology. Part a, Ecological and Integrative Physiology. PMID 29869377 DOI: 10.1002/jez.2187  1
2018 Herbert JA, Kay EJ, Faustini SE, Richter A, Abouelhadid S, Cuccui J, Wren B, Mitchell TJ. Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine. Vaccine. PMID 29778517 DOI: 10.1016/j.vaccine.2018.05.036  1
2018 Mitchell T, MacDonald JW, Srinouanpranchanh S, Bammler TK, Merillat S, Boldenow E, Coleman M, Agnew K, Baldessari A, Stencel-Baerenwald JE, Tisoncik-Go J, Green RR, Gale MJ, Rajagopal L, Adams Waldorf KM. Evidence of cardiac involvement in the fetal inflammatory response syndrome: disruption of gene networks programming cardiac development in nonhuman primates. American Journal of Obstetrics and Gynecology. PMID 29475580 DOI: 10.1016/j.ajog.2018.01.009  0.01
2018 Gutbier B, Neuhauß AK, Reppe K, Ehrler C, Santel A, Kaufmann J, Scholz M, Weissmann N, Morawietz L, Mitchell TJ, Aliberti S, Hippenstiel S, Suttorp N, Witzenrath M. Prognostic and Pathogenic Role of Angiopoietin-1 and -2 in Pneumonia. American Journal of Respiratory and Critical Care Medicine. PMID 29447449 DOI: 10.1164/rccm.201708-1733OC  1
2018 Herbert JA, Mitchell AM, Ritchie R, Ma J, Ross-Hutchinson K, Mitchell TJ. Expression of the lux genes in Streptococcus pneumoniae modulates pilus expression and virulence. Plos One. 13: e0189426. PMID 29342160 DOI: 10.1371/journal.pone.0189426  1
2018 Morozov GI, Porat N, Kushnir T, Najmuldeen H, Adawi A, Chalifa-Caspi V, Benisty R, Ohayon A, Liron O, Azriel S, Malka I, Dotan S, Portnoi M, Piotrowski AA, Kafka D, ... ... Mitchell TJ, et al. Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge. Scientific Reports. 8: 314. PMID 29321514 DOI: 10.1038/S41598-017-18645-8  1
2018 Nerlich A, Mieth M, Letsiou E, Fatykhova D, Zscheppang K, Imai-Matsushima A, Meyer TF, Paasch L, Mitchell TJ, Tönnies M, Bauer TT, Schneider P, Neudecker J, Rückert JC, Eggeling S, et al. Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA. Scientific Reports. 8: 182. PMID 29317705 DOI: 10.1038/S41598-017-18468-7  1
2018 Gutbier B, Schönrock SM, Ehrler C, Haberberger R, Dietert K, Gruber AD, Kummer W, Michalick L, Kuebler WM, Hocke AC, Szymanski K, Letsiou E, Lüth A, Schumacher F, Kleuser B, ... Mitchell TJ, et al. Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2. Critical Care Medicine. PMID 29298188 DOI: 10.1097/CCM.0000000000002916  1
2017 Hulbert AC, Mitchell TS, Hall JM, Guiffre CM, Douglas DC, Warner DA. The effects of incubation temperature and experimental design on heart rates of lizard embryos. Journal of Experimental Zoology. Part a, Ecological and Integrative Physiology. 327: 466-476. PMID 29356429 DOI: 10.1002/jez.2135  1
2017 Warner DA, Mitchell TS, Bodensteiner BL, Janzen FJ. The effect of hormone manipulations on sex ratios varies with environmental conditions in a turtle with temperature-dependent sex determination. Journal of Experimental Zoology. Part a, Ecological and Integrative Physiology. 327: 172-181. PMID 29356364 DOI: 10.1002/jez.2085  1
2017 Gutbier B, Jiang X, Dietert K, Ehrler C, Lienau J, Van Slyke P, Kim H, Hoang VC, Maynes JT, Dumont DJ, Gruber AD, Weissmann N, Mitchell TJ, Suttorp N, Witzenrath M. Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia. Critical Care (London, England). 21: 274. PMID 29132435 DOI: 10.1186/s13054-017-1851-6  1
2017 Hupp S, Ribes S, Seele J, Bischoff C, Förtsch C, Maier E, Benz R, Mitchell TJ, Nau R, Iliev AI. Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation. British Journal of Pharmacology. PMID 28888095 DOI: 10.1111/bph.14027  0.01
2017 Lizcano A, Suresh Babu RA, Shenoy AT, Saville AM, Kumar N, D'Mello A, Hinojosa CA, Gilley RP, Segovia J, Mitchell TJ, Tettelin H, Orihuela CJ. Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties. Microbes and Infection. PMID 28408270 DOI: 10.1016/J.Micinf.2017.04.001  0.01
2017 Nel JG, Durandt C, Theron AJ, Tintinger GR, Pool R, Richards GA, Mitchell TJ, Feldman C, Anderson R. Pneumolysin mediates heterotypic aggregation of neutrophils and platelets in vitro. The Journal of Infection. PMID 28267572 DOI: 10.1016/j.jinf.2017.02.010  1
2017 Maurer J, Hupp S, Bischoff C, Foertsch C, Mitchell TJ, Chakraborty T, Iliev AI. Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes. Toxins. 9. PMID 28098781 DOI: 10.3390/toxins9010034  0.01
2016 Wolfmeier H, Radecke J, Schoenauer R, Koeffel R, Babiychuk VS, Drücker P, Hathaway LJ, Mitchell TJ, Zuber B, Draeger A, Babiychuk EB. Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack. Biochimica Et Biophysica Acta. PMID 27481675 DOI: 10.1016/j.bbagen.2016.07.022  1
2016 Kostadinova E, Chaput C, Gutbier B, Lippmann J, Sander LE, Mitchell TJ, Suttorp N, Witzenrath M, Opitz B. NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence. Scientific Reports. 6: 30943. PMID 27476670 DOI: 10.1038/srep30943  1
2016 Telemeco RS, Gangloff EJ, Cordero GA, Mitchell TS, Bodensteiner BL, Holden KG, Mitchell SM, Polich RL, Janzen FJ. Reptile Embryos Lack the Opportunity to Thermoregulate by Moving within the Egg. The American Naturalist. 188: E13-E27. PMID 27322129 DOI: 10.1086/686628  1
2016 Nel JG, Durandt C, Mitchell TJ, Feldman C, Anderson R, Tintinger GR. Pneumolysin Mediates Platelet Activation In Vitro. Lung. PMID 27192991 DOI: 10.1007/s00408-016-9900-5  1
2016 Mizrachi Nebenzahl Y, Blau K, Kushnir T, Shagan M, Portnoi M, Cohen A, Azriel S, Malka I, Adawi A, Kafka D, Dotan S, Guterman G, Troib S, Fishilevich T, Gershoni JM, ... Mitchell TJ, et al. Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as a Vaccine. Plos One. 11: e0150320. PMID 26990554 DOI: 10.1371/Journal.Pone.0150320  1
2015 Leuthardt EC, Allen M, Kamran M, Hawasli AH, Snyder AZ, Hacker CD, Mitchell TJ, Shimony JS. Resting-State Blood Oxygen Level-Dependent Functional MRI: A Paradigm Shift in Preoperative Brain Mapping. Stereotactic and Functional Neurosurgery. 93: 427-439. PMID 26784290 DOI: 10.1159/000442424  1
2015 Gonçalves MT, Mitchell TJ, Lord JM. Immune ageing and susceptibility to Streptococcus pneumoniae. Biogerontology. PMID 26472172 DOI: 10.1007/s10522-015-9614-8  1
2015 Ahn D, Wier KA, Mitchell TP, Olney PA. Applications of Fast, Facile, Radiation-Free Radical Polymerization Techniques Enabled by Room Temperature Alkylborane Chemistry. Acs Applied Materials & Interfaces. 7: 23902-11. PMID 26465352 DOI: 10.1021/acsami.5b05943  1
2015 Fatykhova D, Rabes A, Machnik C, Guruprasad K, Pache F, Berg J, Toennies M, Bauer TT, Schneider P, Schimek M, Eggeling S, Mitchell TJ, Mitchell AM, Hilker R, Hain T, et al. Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue. Plos One. 10: e0137108. PMID 26317436 DOI: 10.1371/journal.pone.0137108  1
2015 Herbert JA, Mitchell AM, Mitchell TJ. A Serine-Threonine Kinase (StkP) Regulates Expression of the Pneumococcal Pilus and Modulates Bacterial Adherence to Human Epithelial and Endothelial Cells In Vitro. Plos One. 10: e0127212. PMID 26090876 DOI: 10.1371/journal.pone.0127212  1
2015 Chetty P, Choi F, Mitchell T. Primary care review of actinic keratosis and its therapeutic options: a global perspective. Dermatology and Therapy. 5: 19-35. PMID 25647448 DOI: 10.1007/s13555-015-0070-9  1
2014 Kamran M, Hacker CD, Allen MG, Mitchell TJ, Leuthardt EC, Snyder AZ, Shimony JS. Resting-state blood oxygen level-dependent functional magnetic resonance imaging for presurgical planning. Neuroimaging Clinics of North America. 24: 655-69. PMID 25441506 DOI: 10.1016/J.Nic.2014.07.009  1
2014 Bewley MA, Naughton M, Preston J, Mitchell A, Holmes A, Marriott HM, Read RC, Mitchell TJ, Whyte MK, Dockrell DH. Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation. Mbio. 5: e01710-14. PMID 25293758 DOI: 10.1128/mBio.01710-14  1
2014 Cockeran R, Herbert JA, Mitchell TJ, Dix-Peek T, Dickens C, Anderson R, Feldman C. Exposure of a 23F serotype strain of Streptococcus pneumoniae to cigarette smoke condensate is associated with selective upregulation of genes encoding the two-component regulatory system 11 (TCS11). Biomed Research International. 2014: 976347. PMID 25013815 DOI: 10.1155/2014/976347  1
2014 Mitchell T, Cheng E, Jolley J, Delaney S. Successful induction of labor of late-second-trimester conjoined twins: an alternative to hysterotomy. Obstetrics and Gynecology. 123: 469-72. PMID 24413234 DOI: 10.1097/AOG.0000000000000038  1
2014 Frampton SJ, Mitchell TE. Surgical safety issues relating to the use of diathermy in patients with cochlear implants: the patient's perspective. Cochlear Implants International. 15: 48-52. PMID 23692987 DOI: 10.1179/1754762813Y.0000000031  1
2013 Mitchell TS, Maciel JA, Janzen FJ. Does sex-ratio selection influence nest-site choice in a reptile with temperature-dependent sex determination? Proceedings. Biological Sciences / the Royal Society. 280: 20132460. PMID 24266033  1
2013 Mitchell TJ, Hacker CD, Breshears JD, Szrama NP, Sharma M, Bundy DT, Pahwa M, Corbetta M, Snyder AZ, Shimony JS, Leuthardt EC. A novel data-driven approach to preoperative mapping of functional cortex using resting-state functional magnetic resonance imaging. Neurosurgery. 73: 969-82; discussion 9. PMID 24264234 DOI: 10.1227/Neu.0000000000000141  1
2013 Smith A, Johnston C, Inverarity D, Slack M, Paterson GK, Diggle M, Mitchell T. Investigating the role of pneumococcal neuraminidase A activity in isolates from pneumococcal haemolytic uraemic syndrome. Journal of Medical Microbiology. 62: 1735-42. PMID 23924664 DOI: 10.1099/jmm.0.063479-0  0.01
2013 Wippel C, Maurer J, Förtsch C, Hupp S, Bohl A, Ma J, Mitchell TJ, Bunkowski S, Brück W, Nau R, Iliev AI. Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage. Plos Pathogens. 9: e1003380. PMID 23785278 DOI: 10.1371/journal.ppat.1003380  1
2013 Mitchell TS, Warner DA, Janzen FJ. Phenotypic and fitness consequences of maternal nest-site choice across multiple early life stages. Ecology. 94: 336-45. PMID 23691653 DOI: 10.1890/12-0343.1  1
2013 Proctor RD, Gawne-Cain ML, Eyles J, Mitchell TE, Batty VB. MRI during cochlear implant assessment: Should we image the whole brain? Cochlear Implants International. 14: 2-6. PMID 23340090 DOI: 10.1179/1754762811Y.0000000029  1
2013 Hupp S, Förtsch C, Wippel C, Ma J, Mitchell TJ, Iliev AI. Direct transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysin. Journal of Molecular Biology. 425: 636-46. PMID 23219469 DOI: 10.1016/j.jmb.2012.11.034  1
2013 Warner DA, Mitchell TS. Does maternal oviposition site influence offspring dispersal to suitable habitat? Oecologia. 172: 679-88. PMID 23196739 DOI: 10.1007/s00442-012-2533-3  1
2013 Mitchell TJ, Neil JJ, Zempel JM, Thio LL, Inder TE, Bretthorst GL. Automating the analysis of EEG recordings from prematurely-born infants: a Bayesian approach. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 124: 452-61. PMID 23014143 DOI: 10.1016/J.Clinph.2012.09.003  1
2012 Wiertsema SP, Corscadden KJ, Mowe EN, Zhang G, Vijayasekaran S, Coates HL, Mitchell TJ, Thomas WR, Richmond PC, Kirkham LA. IgG responses to Pneumococcal and Haemophilus influenzae protein antigens are not impaired in children with a history of recurrent acute otitis media. Plos One. 7: e49061. PMID 23152850 DOI: 10.1371/journal.pone.0049061  0.04
2012 Chimalapati S, Cohen JM, Camberlein E, MacDonald N, Durmort C, Vernet T, Hermans PW, Mitchell T, Brown JS. Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo. Plos One. 7: e41393. PMID 22911788 DOI: 10.1371/journal.pone.0041393  0.01
2012 Dockrell DH, Whyte MK, Mitchell TJ. Pneumococcal pneumonia: mechanisms of infection and resolution. Chest. 142: 482-91. PMID 22871758 DOI: 10.1378/chest.12-0210  1
2012 Daigneault M, De Silva TI, Bewley MA, Preston JA, Marriott HM, Mitchell AM, Mitchell TJ, Read RC, Whyte MK, Dockrell DH. Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. Plos Pathogens. 8: e1002814. PMID 22829769 DOI: 10.1371/journal.ppat.1002814  1
2012 Lucas R, Yang G, Gorshkov BA, Zemskov EA, Sridhar S, Umapathy NS, Jezierska-Drutel A, Alieva IB, Leustik M, Hossain H, Fischer B, Catravas JD, Verin AD, Pittet JF, Caldwell RB, Mitchell TJ, et al. Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability. American Journal of Respiratory Cell and Molecular Biology. 47: 445-53. PMID 22582175 DOI: 10.1165/Rcmb.2011-0332Oc  1
2012 Marriott HM, Gascoyne KA, Gowda R, Geary I, Nicklin MJ, Iannelli F, Pozzi G, Mitchell TJ, Whyte MK, Sabroe I, Dockrell DH. Interleukin-1β regulates CXCL8 release and influences disease outcome in response to Streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages. Infection and Immunity. 80: 1140-9. PMID 22158745 DOI: 10.1128/IAI.05697-11  1
2012 Hupp S, Heimeroth V, Wippel C, Förtsch C, Ma J, Mitchell TJ, Iliev AI. Astrocytic tissue remodeling by the meningitis neurotoxin pneumolysin facilitates pathogen tissue penetration and produces interstitial brain edema. Glia. 60: 137-46. PMID 21989652 DOI: 10.1002/glia.21256  1
2011 Hiller NL, Eutsey RA, Powell E, Earl JP, Janto B, Martin DP, Dawid S, Ahmed A, Longwell MJ, Dahlgren ME, Ezzo S, Tettelin H, Daugherty SC, Mitchell TJ, Hillman TA, et al. Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. Plos One. 6: e28850. PMID 22205975 DOI: 10.1371/Journal.Pone.0028850  1
2011 Pido-Lopez J, Kwok WW, Mitchell TJ, Heyderman RS, Williams NA. Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue. Plos Pathogens. 7: e1002396. PMID 22144893 DOI: 10.1371/journal.ppat.1002396  1
2011 Förtsch C, Hupp S, Ma J, Mitchell TJ, Maier E, Benz R, Iliev AI. Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity. Toxins. 3: 43-62. PMID 22069689 DOI: 10.3390/toxins3010043  1
2011 Wippel C, Förtsch C, Hupp S, Maier E, Benz R, Ma J, Mitchell TJ, Iliev AI. Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue. The Journal of Infectious Diseases. 204: 930-6. PMID 21849290 DOI: 10.1093/infdis/jir434  1
2011 Witzenrath M, Pache F, Lorenz D, Koppe U, Gutbier B, Tabeling C, Reppe K, Meixenberger K, Dorhoi A, Ma J, Holmes A, Trendelenburg G, Heimesaat MM, Bereswill S, van der Linden M, ... Mitchell TJ, et al. The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia. Journal of Immunology (Baltimore, Md. : 1950). 187: 434-40. PMID 21646297 DOI: 10.4049/jimmunol.1003143  1
2011 Bewley MA, Marriott HM, Tulone C, Francis SE, Mitchell TJ, Read RC, Chain B, Kroemer G, Whyte MK, Dockrell DH. A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci. Plos Pathogens. 7: e1001262. PMID 21298030 DOI: 10.1371/Journal.Ppat.1001262  1
2011 Croucher NJ, Harris SR, Fraser C, Quail MA, Burton J, van der Linden M, McGee L, von Gottberg A, Song JH, Ko KS, Pichon B, Baker S, Parry CM, Lambertsen LM, Shahinas D, ... Mitchell TJ, et al. Rapid pneumococcal evolution in response to clinical interventions. Science (New York, N.Y.). 331: 430-4. PMID 21273480 DOI: 10.1126/Science.1198545  1
2011 Dogan S, Zhang Q, Pridmore AC, Mitchell TJ, Finn A, Murdoch C. Pneumolysin-induced CXCL8 production by nasopharyngeal epithelial cells is dependent on calcium flux and MAPK activation via Toll-like receptor 4. Microbes and Infection / Institut Pasteur. 13: 65-75. PMID 20974276 DOI: 10.1016/j.micinf.2010.10.003  0.01
2010 Inverarity D, Diggle M, Ure R, Santana-Hernandez D, Altstadt P, Mitchell T, Edwards G. Simultaneous nasopharyngeal carriage of two pneumococcal multilocus sequence types with a serotype 3 phenotype. International Journal of Microbiology. 2010: 765479. PMID 21151653 DOI: 10.1155/2010/765479  1
2010 Cooke B, Smith A, Diggle M, Lamb K, Robertson C, Inverarity D, Jefferies J, Edwards G, Mitchell T, Clarke S, McMenamin J. Antibiotic resistance in invasive Streptococcus pneumoniae isolates identified in Scotland between 1999 and 2007. Journal of Medical Microbiology. 59: 1212-8. PMID 20651042 DOI: 10.1099/jmm.0.022954-0  0.01
2010 Rush CM, Mitchell TJ, Garside P. A detailed characterisation of the distribution and presentation of DNA vaccine encoded antigen. Vaccine. 28: 1620-34. PMID 20035828 DOI: 10.1016/j.vaccine.2009.11.014  1
2010 Yuste J, Khandavilli S, Ansari N, Muttardi K, Ismail L, Hyams C, Weiser J, Mitchell T, Brown JS. The effects of PspC on complement-mediated immunity to Streptococcus pneumoniae vary with strain background and capsular serotype. Infection and Immunity. 78: 283-92. PMID 19884335 DOI: 10.1128/Iai.00541-09  0.01
2009 Mureithi MW, Finn A, Ota MO, Zhang Q, Davenport V, Mitchell TJ, Williams NA, Adegbola RA, Heyderman RS. T cell memory response to pneumococcal protein antigens in an area of high pneumococcal carriage and disease. The Journal of Infectious Diseases. 200: 783-93. PMID 19642930 DOI: 10.1086/605023  0.01
2009 Koya E, Golden SA, Harvey BK, Guez-Barber DH, Berkow A, Simmons DE, Bossert JM, Nair SG, Uejima JL, Marin MT, Mitchell TB, Farquhar D, Ghosh SC, Mattson BJ, Hope BT. Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization. Nature Neuroscience. 12: 1069-73. PMID 19620976 DOI: 10.1038/Nn.2364  1
2009 Hughes TR, Ross KS, Cowan GJ, Sivasankar B, Harris CL, Mitchell TJ, Morgan BP. Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59. Molecular Immunology. 46: 1561-7. PMID 19200600 DOI: 10.1016/j.molimm.2009.01.003  1
2009 Witzenrath M, Gutbier B, Schmeck B, Tenor H, Seybold J, Kuelzer R, Grentzmann G, Hatzelmann A, van Laak V, Tschernig T, Mitchell TJ, Schudt C, Rosseau S, Suttorp N, Schütte H. Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia. Critical Care Medicine. 37: 584-90. PMID 19114892 DOI: 10.1097/CCM.0b013e3181959814  1
2009 Iliev AI, Djannatian JR, Opazo F, Gerber J, Nau R, Mitchell TJ, Wouters FS. Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol-dependent, non-lytic and Src-kinase dependent manner inhibits intracellular trafficking. Molecular Microbiology. 71: 461-77. PMID 19040644 DOI: 10.1111/J.1365-2958.2008.06538.X  1
2008 Marriott HM, Mitchell TJ, Dockrell DH. Pneumolysin: a double-edged sword during the host-pathogen interaction. Current Molecular Medicine. 8: 497-509. PMID 18781957 DOI: 10.2174/156652408785747924  1
2008 Mattson BJ, Koya E, Simmons DE, Mitchell TB, Berkow A, Crombag HS, Hope BT. Context-specific sensitization of cocaine-induced locomotor activity and associated neuronal ensembles in rat nucleus accumbens. The European Journal of Neuroscience. 27: 202-12. PMID 18093170 DOI: 10.1111/J.1460-9568.2007.05984.X  1
2008 Khandavilli S, Homer KA, Yuste J, Basavanna S, Mitchell T, Brown JS. Maturation of Streptococcus pneumoniae lipoproteins by a type II signal peptidase is required for ABC transporter function and full virulence. Molecular Microbiology. 67: 541-57. PMID 18086214 DOI: 10.1111/j.1365-2958.2007.06065.x  1
2007 Goos M, Zech WD, Jaiswal MK, Balakrishnan S, Ebert S, Mitchell T, Carrì MT, Keller BU, Nau R. Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury. Bmc Infectious Diseases. 7: 131. PMID 17997855 DOI: 10.1186/1471-2334-7-131  1
2007 Spreer A, von Ruden C, Mitchell TJ, Eiffert H, Nau R. Influence of subinhibitory concentrations of protein-synthesis-inhibiting antibiotics on production and release of the pneumococcal virulence factor pneumolysin in vitro. Chemotherapy. 53: 327-31. PMID 17728540 DOI: 10.1159/000107691  1
2007 Lintzeris N, Mitchell TB, Bond AJ, Nestor L, Strang J. Pharmacodynamics of diazepam co-administered with methadone or buprenorphine under high dose conditions in opioid dependent patients. Drug and Alcohol Dependence. 91: 187-94. PMID 17624687 DOI: 10.1016/j.drugalcdep.2007.05.019  0.01
2007 Witzenrath M, Gutbier B, Owen JS, Schmeck B, Mitchell TJ, Mayer K, Thomas MJ, Ishii S, Rosseau S, Suttorp N, Schütte H. Role of platelet-activating factor in pneumolysin-induced acute lung injury. Critical Care Medicine. 35: 1756-62. PMID 17522574 DOI: 10.1097/01.Ccm.0000269212.84709.23  1
2007 Iliev AI, Djannatian JR, Nau R, Mitchell TJ, Wouters FS. Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin. Proceedings of the National Academy of Sciences of the United States of America. 104: 2897-902. PMID 17301241 DOI: 10.1073/Pnas.0608213104  1
2006 Mitchell TB, White JM, Somogyi AA, Bochner F. Switching between methadone and morphine for maintenance treatment of opioid dependence: impact on pain sensitivity and mood status. The American Journal On Addictions / American Academy of Psychiatrists in Alcoholism and Addictions. 15: 311-5. PMID 16867927 DOI: 10.1080/10550490600754374  1
2006 Martinez Devesa P, Mitchell TE, Scott I, Moffat DA. Malignant peripheral nerve sheath tumors of the head and neck: two cases and a review of the literature. Ear, Nose, & Throat Journal. 85: 392-6. PMID 16866118  0.01
2006 Zhang Q, Bernatoniene J, Bagrade L, Paton JC, Mitchell TJ, Hammerschmidt S, Nunez DA, Finn A. Regulation of production of mucosal antibody to pneumococcal protein antigens by T-cell-derived gamma interferon and interleukin-10 in children. Infection and Immunity. 74: 4735-43. PMID 16861661 DOI: 10.1128/IAI.00165-06  0.01
2006 Clarke SC, Jefferies JM, Smith AJ, McMenamin J, Mitchell TJ, Edwards GF. Pneumococci causing invasive disease in children prior to the introduction of pneumococcal conjugate vaccine in Scotland. Journal of Medical Microbiology. 55: 1079-84. PMID 16849728 DOI: 10.1099/jmm.0.46550-0  0.01
2006 Paterson NG, Riboldi-Tunnicliffe A, Mitchell TJ, Isaacs NW. Purification, crystallization and preliminary X-ray diffraction analysis of RafE, a sugar-binding lipoprotein from Streptococcus pneumoniae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 676-9. PMID 16820692 DOI: 10.1107/S1744309106021695  1
2006 Paterson NG, Riboldi-Tunicliffe A, Mitchell TJ, Isaacs NW. Overexpression, purification and crystallization of a choline-binding protein CbpI from Streptococcus pneumoniae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 672-5. PMID 16820691 DOI: 10.1107/S1744309106020616  1
2006 Mitchell TB, Dyer KR, Newcombe D, Somogyi AA, White JM. Fluctuations in (R,S)-methadone pharmacokinetics and response among long-term methadone maintenance patients. Addiction Biology. 11: 170-4. PMID 16800831 DOI: 10.1111/j.1369-1600.2006.00014.x  1
2006 Witzenrath M, Gutbier B, Hocke AC, Schmeck B, Hippenstiel S, Berger K, Mitchell TJ, de los Toyos JR, Rosseau S, Suttorp N, Schütte H. Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia. Critical Care Medicine. 34: 1947-54. PMID 16715037 DOI: 10.1097/01.CCM.0000220496.48295.A9  1
2006 Lintzeris N, Mitchell TB, Bond A, Nestor L, Strang J. Interactions on mixing diazepam with methadone or buprenorphine in maintenance patients. Journal of Clinical Psychopharmacology. 26: 274-83. PMID 16702892 DOI: 10.1097/01.jcp.0000219050.33008.61  0.01
2006 Clarke SC, Jefferies JM, Smith AJ, McMenamin J, Mitchell TJ, Edwards GF. Potential impact of conjugate vaccine on the incidence of invasive pneumococcal disease among children in Scotland. Journal of Clinical Microbiology. 44: 1224-8. PMID 16597842 DOI: 10.1128/JCM.44.4.1224-1228.2006  0.01
2006 Mitchell TB, Lintzeris N, Bond A, Strang J. Feasibility and acceptability of an intranasal diamorphine spray as an alternative to injectable diamorphine for maintenance treatment. European Addiction Research. 12: 91-5. PMID 16543744 DOI: 10.1159/000090428  0.01
2006 Mitchell TB, Dyer KR, Peay ER. Patient and physician characteristics in relation to clinical decision making in methadone maintenance treatment. Substance Use & Misuse. 41: 393-404. PMID 16467013 DOI: 10.1080/10826080500409043  0.01
2006 Zhang Q, Bernatoniene J, Bagrade L, Pollard AJ, Mitchell TJ, Paton JC, Finn A. Serum and mucosal antibody responses to pneumococcal protein antigens in children: relationships with carriage status. European Journal of Immunology. 36: 46-57. PMID 16342325 DOI: 10.1002/eji.200535101  0.01
2006 Rush CM, Mitchell TJ, Burke B, Garside P. Dissecting the components of the humoral immune response elicited by DNA vaccines Vaccine. 24: 776-784. PMID 16198029 DOI: 10.1016/j.vaccine.2005.08.080  1
2005 Harraghy N, Mitchell TJ. Isolation and characterization of the promoter and partial enhancer region of the porcine inter-α-trypsin inhibitor heavy chain 4 gene Clinical and Diagnostic Laboratory Immunology. 12: 1336-1339. PMID 16275952 DOI: 10.1128/CDLI.12.11.1336-1339.2005  1
2005 Schröter D, Cramer W, Leemans R, Prentice IC, Araújo MB, Arnell NW, Bondeau A, Bugmann H, Carter TR, Gracia CA, de la Vega-Leinert AC, Erhard M, Ewert F, Glendining M, House JI, ... Mitchell TD, et al. Ecosystem service supply and vulnerability to global change in Europe. Science (New York, N.Y.). 310: 1333-7. PMID 16254151 DOI: 10.1126/science.1115233  1
2005 Chen S, Paterson GK, Tong HH, Mitchell TJ, DeMaria TF. Sortase A contributes to pneumococcal nasopharyngeal colonization in the chinchilla model. Fems Microbiology Letters. 253: 151-4. PMID 16246506 DOI: 10.1016/j.femsle.2005.09.052  1
2005 Ebert S, Dietz GP, Mitchell TJ, Michel U, Bähr M, Nau R. Limited protection of TAT-Bcl-X(L) against pneumolysin-induced neuronal cell death. Neuroscience Letters. 384: 349-53. PMID 15961228 DOI: 10.1016/J.Neulet.2005.05.027  0.01
2005 Mitchell TK, Nguyen AV, Evans GM. Heterocoagulation of chalcopyrite and pyrite minerals in flotation separation Advances in Colloid and Interface Science. 114: 227-237. PMID 15894282 DOI: 10.1016/j.cis.2004.08.009  1
2005 Ebert S, Gerber J, Bader S, Mühlhauser F, Brechtel K, Mitchell TJ, Nau R. Dose-dependent activation of microglial cells by Toll-like receptor agonists alone and in combination. Journal of Neuroimmunology. 159: 87-96. PMID 15652406 DOI: 10.1016/j.jneuroim.2004.10.005  0.01
2004 Jefferies JMC, Smith A, Clarke SC, Dowson C, Mitchell TJ. Genetic analysis of diverse disease-causing pneumococci indicates high levels of diversity within serotypes and capsule switching Journal of Clinical Microbiology. 42: 5681-5688. PMID 15583299 DOI: 10.1128/JCM.42.12.5681-5688.2004  1
2004 Mitchell TB, Dyer KR, Newcombe D, Salter A, Somogyi AA, Bochner F, White JM. Subjective and physiological responses among racemic-methadone maintenance patients in relation to relative (S)- vs. (R)-methadone exposure. British Journal of Clinical Pharmacology. 58: 609-17. PMID 15563359 DOI: 10.1111/j.1365-2125.2004.02221.x  0.01
2004 Skinner LJ, Beurg M, Mitchell TJ, Darrouzet V, Aran JM, Dulon D. Intracochlear perfusion of pneumolysin, a pneumococcal protein, rapidly abolishes auditory potentials in the Guinea pig cochlea. Acta Oto-Laryngologica. 124: 1000-7. PMID 15513541 DOI: 10.1080/00016480410017125  0.01
2004 Hirst RA, Mohammed BJ, Mitchell TJ, Andrew PW, O'Callaghan C. Streptococcus pneumoniae-induced inhibition of rat ependymal cilia is attenuated by antipneumolysin antibody Infection and Immunity. 72: 6694-6698. PMID 15501805 DOI: 10.1128/IAI.72.11.6694-6698.2004  1
2004 Nagamune H, Ohkura K, Sukeno A, Cowan G, Mitchell TJ, Ito W, Ohnishi O, Hattori K, Yamato M, Hirota K, Miyake Y, Maeda T, Kourai H. The human-specific action of intermedilysin, a homolog of streptolysin O, is dictated by domain 4 of the protein. Microbiology and Immunology. 48: 677-92. PMID 15383705 DOI: 10.1111/j.1348-0421.2004.tb03479.x  1
2004 Mitchell TB, White JM, Somogyi AA, Bochner F. Slow-release oral morphine versus methadone: a crossover comparison of patient outcomes and acceptability as maintenance pharmacotherapies for opioid dependence. Addiction (Abingdon, England). 99: 940-5. PMID 15265090 DOI: 10.1111/j.1360-0443.2004.00764.x  0.01
2004 Solovyova AS, Nöllmann M, Mitchell TJ, Byron O. The solution structure and oligomerization behavior of two bacterial toxins: Pneumolysin and perfringolysin O Biophysical Journal. 87: 540-552. PMID 15240487 DOI: 10.1529/biophysj.104.039974  1
2004 Cockeran R, Theron AJ, Feldman C, Mitchell TJ, Anderson R. Docosahexaenoic acid and eicosapentaenoic acid antagonize the proinflammatory interactions of pneumolysin with human neutrophils Infection and Immunity. 72: 4327-4329. PMID 15213185 DOI: 10.1128/IAI.72.7.4327-4329.2004  1
2004 Nöllmann M, Gilbert R, Mitchell T, Sferrazza M, Byron O. The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin. Biophysical Journal. 86: 3141-51. PMID 15111427 DOI: 10.1016/S0006-3495(04)74362-3  0.01
2004 Riboldi-Tunnicliffe A, Trombe MC, Bent CJ, Isaacs NW, Mitchell TJ. Crystallization and preliminary crystallographic studies of the D59A mutant of MicA, a YycF response-regulator homologue from Streptococcus pneumoniae. Acta Crystallographica. Section D, Biological Crystallography. 60: 950-1. PMID 15103149 DOI: 10.1107/S0907444904005712  0.01
2004 Riboldi-Tunnicliffe A, Bent CJ, Isaacs NW, Mitchell TJ. Expression, purification and X-ray characterization of residues 18-230 from the pneumococcal histidine triad protein A (PhtA) from Streptococcus pneumoniae Acta Crystallographica Section D: Biological Crystallography. 60: 926-928. PMID 15103141 DOI: 10.1107/S0907444904004573  1
2004 Bent CJ, Isaacs NW, Mitchell TJ, Riboldi-Tunnicliffe A. Crystal Structure of the Response Regulator 02 Receiver Domain, the Essential YycF Two-Component System of Streptococcus pneumoniae in both Complexed and Native States Journal of Bacteriology. 186: 2872-2879. PMID 15090529 DOI: 10.1128/JB.186.9.2872-2879.2004  1
2004 Paterson GK, Mitchell TJ. The biology of Gram-positive sortase enzymes Trends in Microbiology. 12: 89-95. PMID 15036325 DOI: 10.1016/j.tim.2003.12.007  1
2003 Mitchell TJ. The pathogenesis of streptococcal infections: from tooth decay to meningitis Nature Reviews. Microbiology. 1: 219-230. PMID 15035026  1
2003 Mitchell TB, White JM, Somogyi AA, Bochner F. Comparative pharmacodynamics and pharmacokinetics of methadone and slow-release oral morphine for maintenance treatment of opioid dependence. Drug and Alcohol Dependence. 72: 85-94. PMID 14563546 DOI: 10.1016/S0376-8716(03)00190-X  0.01
2003 Spreer A, Kerstan H, Böttcher T, Gerber J, Siemer A, Zysk G, Mitchell TJ, Eiffert H, Nau R. Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone. Antimicrobial Agents and Chemotherapy. 47: 2649-54. PMID 12878534 DOI: 10.1128/AAC.47.8.2649-2654.2003  1
2003 Bent CJ, Isaacs NW, Mitchell TJ, Riboldi-Tunnicliffe A. Cloning, overexpression, purification, crystallization and preliminary diffraction analysis of the receiver domain of MicA Acta Crystallographica - Section D Biological Crystallography. 59: 758-760. PMID 12657804 DOI: 10.1107/S090744490300372X  1
2003 Riboldi-Tunnicliffe A, Bent CJ, Isaacs NW, Mitchell TJ. Purification, crystallization and preliminary X-ray analysis of the Enterococcus faecalis protein EF0377 Acta Crystallographica - Section D Biological Crystallography. 59: 755-757. PMID 12657803 DOI: 10.1107/S0907444903003718  1
2002 McCluskey J, Dowson CG, Mitchell TJ. The use of microarray technology for the analysis of Streptococcus pneumoniae. Comparative and Functional Genomics. 3: 366-8. PMID 18629276 DOI: 10.1002/cfg.190  1
2002 Stringaris AK, Geisenhainer J, Bergmann F, Balshüsemann C, Lee U, Zysk G, Mitchell TJ, Keller BU, Kuhnt U, Gerber J, Spreer A, Bähr M, Michel U, Nau R. Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase. Neurobiology of Disease. 11: 355-68. PMID 12586546 DOI: 10.1006/Nbdi.2002.0561  1
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