James O Wrabl - Publications

Affiliations: 
Biology Johns Hopkins University, Baltimore, MD 

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 White JT, Rives J, Tharp ME, Wrabl JO, Thompson EB, Hilser VJ. Tumor Susceptibility Gene 101 Regulates the Glucocorticoid Receptor through Disorder-Mediated Allostery. Biochemistry. PMID 34009973 DOI: 10.1021/acs.biochem.1c00079  0.84
2021 Grasso EM, Majumdar A, Wrabl JO, Frueh DP, Hilser VJ. Conserved allosteric ensembles in a disordered protein using TROSY/Anti-TROSY R-filtered spectroscopy. Biophysical Journal. PMID 33901472 DOI: 10.1016/j.bpj.2021.04.017  0.84
2020 Cho MH, Wrabl JO, Taylor J, Hilser VJ. Hidden dynamic signatures drive substrate selectivity in the disordered phosphoproteome. Proceedings of the National Academy of Sciences of the United States of America. PMID 32900925 DOI: 10.1073/Pnas.1921473117  0.84
2018 Hoffmann J, Wrabl JO, Hilser VJ. The role of negative selection in protein evolution revealed through the energetics of the native sate ensemble. Proteins. 86: 1313. PMID 30549116 DOI: 10.1002/prot.25484  0.84
2018 Saavedra HG, Wrabl JO, Anderson JA, Li J, Hilser VJ. Dynamic allostery can drive cold adaptation in enzymes. Nature. PMID 29875414 DOI: 10.1038/S41586-018-0183-2  0.84
2018 White JT, Li J, Grasso E, Wrabl JO, Hilser VJ. Ensemble allosteric model: energetic frustration within the intrinsically disordered glucocorticoid receptor. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29735729 DOI: 10.1098/Rstb.2017.0175  0.84
2018 Li J, White JT, Saavedra H, Wrabl JO, Motlagh HN, Liu K, Sowers J, Schroer TA, Thompson EB, Hilser VJ. Correction: Genetically tunable frustration controls allostery in an intrinsically disordered transcription factor. Elife. 7. PMID 29431606 DOI: 10.7554/eLife.35768  0.84
2017 Li J, White JT, Saavedra H, Wrabl JO, Motlagh HN, Liu K, Sowers J, Schroer T, Thompson EB, Hilser VJ. Genetically tunable frustration controls allostery in an intrinsically disordered transcription factor. Elife. 6. PMID 29022880 DOI: 10.7554/Elife.30688  0.84
2016 Hoffmann J, Wrabl JO, Hilser VJ. The role of negative selection in protein evolution revealed through the energetics of the native state ensemble. Proteins. 84: 435-47. PMID 26800099 DOI: 10.1002/Prot.24989  0.84
2016 Hoffmann J, Wrabl JO, Hilser VJ. The role of negative selection in protein evolution revealed through the energetics of the native state ensemble Proteins: Structure, Function and Bioinformatics. 84: 435-447. DOI: 10.1002/prot.24989  0.8
2014 Motlagh HN, Wrabl JO, Li J, Hilser VJ. The ensemble nature of allostery. Nature. 508: 331-9. PMID 24740064 DOI: 10.1038/Nature13001  0.8
2013 Hadzipasic O, Wrabl JO, Hilser VJ. A horizontal alignment tool for numerical trend discovery in sequence data: application to protein hydropathy. Plos Computational Biology. 9: e1003247. PMID 24130469 DOI: 10.1371/Journal.Pcbi.1003247  0.8
2013 Schrank TP, Wrabl JO, Hilser VJ. Conformational heterogeneity within the LID domain mediates substrate binding to Escherichia coli adenylate kinase: function follows fluctuations. Topics in Current Chemistry. 337: 95-121. PMID 23543318 DOI: 10.1007/128_2012_410  0.8
2012 Hilser VJ, Wrabl JO, Motlagh HN. Structural and energetic basis of allostery. Annual Review of Biophysics. 41: 585-609. PMID 22577828 DOI: 10.1146/Annurev-Biophys-050511-102319  0.8
2011 Wrabl JO, Gu J, Liu T, Schrank TP, Whitten ST, Hilser VJ. The role of protein conformational fluctuations in allostery, function, and evolution. Biophysical Chemistry. 159: 129-41. PMID 21684672 DOI: 10.1016/J.Bpc.2011.05.020  0.8
2010 Wrabl JO, Hilser VJ. Investigating homology between proteins using energetic profiles. Plos Computational Biology. 6: e1000722. PMID 20361049 DOI: 10.1371/Journal.Pcbi.1000722  0.8
2009 Vertrees J, Wrabl JO, Hilser VJ. An energetic representation of protein architecture that is independent of primary and secondary structure. Biophysical Journal. 97: 1461-70. PMID 19720035 DOI: 10.1016/J.Bpj.2009.06.020  0.8
2009 Vertrees J, Wrabl JO, Hilser VJ. Energetic profiling of protein folds. Methods in Enzymology. 455: 299-327. PMID 19289211 DOI: 10.1016/S0076-6879(08)04211-0  0.8
2008 Wrabl JO, Grishin NV. Statistics of random protein superpositions: p-values for pairwise structure alignment. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 15: 317-55. PMID 18333756 DOI: 10.1089/Cmb.2007.0161  0.8
2005 Wrabl JO, Grishin NV. Grouping of amino acid types and extraction of amino acid properties from multiple sequence alignments using variance maximization Proteins: Structure, Function and Genetics. 61: 523-534. PMID 16184599 DOI: 10.1002/Prot.20648  0.8
2003 Kinch LN, Wrabl JO, Krishna SS, Majumdar I, Sadreyev RI, Qi Y, Pei J, Cheng H, Grishin NV. CASP5 assessment of fold recognition target predictions. Proteins. 53: 395-409. PMID 14579328 DOI: 10.1002/Prot.10557  0.8
2002 Wrabl JO, Larson SA, Hilser VJ. Thermodynamic environments in proteins: fundamental determinants of fold specificity. Protein Science : a Publication of the Protein Society. 11: 1945-57. PMID 12142449 DOI: 10.1110/Ps.0203202  0.8
2001 Wrabl JO, Larson SA, Hilser VJ. Thermodynamic propensities of amino acids in the native state ensemble: Implications for fold recognition Protein Science. 10: 1032-1045. PMID 11316884 DOI: 10.1110/ps.01601  0.8
2000 Wooll JO, Wrabl JO, Hilser VJ. Ensemble modulation as an origin of denaturant-independent hydrogen exchange in proteins Journal of Molecular Biology. 301: 247-256. PMID 10926507 DOI: 10.1006/Jmbi.2000.3889  0.8
2000 Wrabl JO, Shortle D, Woolf TB. Correlation between changes in nuclear magnetic resonance order parameters and conformational entropy: molecular dynamics simulations of native and denatured staphylococcal nuclease. Proteins. 38: 123-33. PMID 10656260 DOI: 10.1002/(Sici)1097-0134(20000201)38:2<123::Aid-Prot2>3.0.Co;2-H  0.8
1999 Wrabl J, Shortle D. A model of the changes in denatured state structure underlying m value effects in staphylococcal nuclease Nature Structural Biology. 6: 876-883. PMID 10467101 DOI: 10.1038/12338  0.8
1996 O'Brien R, Sturtevant JM, Wrabl J, Holtzer ME, Holtzer A. A scanning calorimetric study of unfolding equilibria in homodimeric chicken gizzard tropomyosins. Biophysical Journal. 70: 2403-7. PMID 9172766 DOI: 10.1016/S0006-3495(96)79808-9  0.8
1996 Wrabl JO, Shortle D. Perturbations of the denatured state ensemble: Modeling their effects on protein stability and folding kinetics Protein Science. 5: 2343-2352. PMID 8931153 DOI: 10.1002/Pro.5560051121  0.8
1996 Shortle D, Wang Y, Gillespie JR, Wrabl JO. Protein folding for realists: A timeless phenomenon Protein Science. 5: 991-1000. PMID 8762131 DOI: 10.1002/Pro.5560050602  0.8
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