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Linda Griffith - Publications

Affiliations: 
Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Website:
https://be.mit.edu/directory/linda-g-griffith
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86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhang J, Huang Y, Trapecar M, Wright C, Schneider K, Kemmit J, Hernandez-Gordillo V, Griffith L, Alm E, Trumper D, Yoon JY, Breault D. An immune-competent human gut microphysiological system enables inflammation-modulation of Faecalibacterium prausnitzii. Research Square. PMID 37886530 DOI: 10.21203/rs.3.rs-3373576/v1  0.442
2021 Zhang J, Hernandez-Gordillo V, Trapecar M, Wright C, Taketani M, Schneider K, Chen WLK, Stas E, Breault DT, Carrier RL, Voigt CA, Griffith LG. Coculture of primary human colon monolayer with human gut bacteria. Nature Protocols. PMID 34183870 DOI: 10.1038/s41596-021-00562-w  0.476
2021 Chen WLK, Suter E, Miyazaki H, Velazquez J, Lauffenburger DA, Griffith LG, Carrier RL. Synergistic Action of Diclofenac with Endotoxin-Mediated Inflammation Exacerbates Intestinal Injury . Acs Infectious Diseases. PMID 33745271 DOI: 10.1021/acsinfecdis.0c00762  0.433
2021 Trapecar M, Wogram E, Svoboda D, Communal C, Omer A, Lungjangwa T, Sphabmixay P, Velazquez J, Schneider K, Wright CW, Mildrum S, Hendricks A, Levine S, Muffat J, Lee MJ, ... ... Griffith LG, et al. Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases. Science Advances. 7. PMID 33514545 DOI: 10.1126/sciadv.abd1707  0.407
2021 Zhang J, Huang YJ, Yoon JY, Kemmitt J, Wright C, Schneider K, Sphabmixay P, Hernandez-Gordillo V, Holcomb SJ, Bhushan B, Rohatgi G, Benton K, Carpenter D, Kester JC, Eng G, ... ... Griffith LG, et al. Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive in continuous culture. Med (New York, N.Y.). 2: 74-98.e9. PMID 33511375 DOI: 10.1016/j.medj.2020.07.001  0.436
2020 Taketani M, Zhang J, Zhang S, Triassi AJ, Huang YJ, Griffith LG, Voigt CA. Author Correction: Genetic circuit design automation for the gut resident species Bacteroides thetaiotaomicron. Nature Biotechnology. 38: 1001. PMID 32760018 DOI: 10.1038/S41587-020-0545-9  0.349
2020 Taketani M, Zhang J, Zhang S, Triassi AJ, Huang YJ, Griffith LG, Voigt CA. Genetic circuit design automation for the gut resident species Bacteroides thetaiotaomicron. Nature Biotechnology. PMID 32231334 DOI: 10.1038/S41587-020-0468-5  0.41
2020 Kester JC, Brubaker DK, Velazquez J, Wright C, Lauffenburger DA, Griffith LG. -associated antibiotics alter human mucosal barrier functions by microbiome-independent mechanisms. Antimicrobial Agents and Chemotherapy. PMID 31988098 DOI: 10.1128/Aac.01404-19  0.394
2019 Ahrens CC, Chiswick EL, Ravindra KC, Miller MA, Ramseier J, Isaacson KB, Lauffenburger DA, Griffith LG. Development and Application of the Metalloprotease Activity Multi-plexed Bead-based Immunoassay (MAMBI). Biochemistry. PMID 31474112 DOI: 10.1021/Acs.Biochem.9B00584  0.416
2018 Yoneyama T, Gorry M, Sobo-Vujanovic A, Lin Y, Vujanovic L, Gaither-Davis A, Moss ML, Miller MA, Griffith LG, Lauffenburger DA, Stabile LP, Herman J, Vujanovic NL. ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker. Journal of Cancer. 9: 2559-2570. PMID 30026855 DOI: 10.7150/Jca.24601  0.409
2018 Chan HF, Zhao R, Parada GA, Meng H, Leong KW, Griffith LG, Zhao X. Folding artificial mucosa with cell-laden hydrogels guided by mechanics models. Proceedings of the National Academy of Sciences of the United States of America. PMID 29967135 DOI: 10.1073/Pnas.1802361115  0.719
2018 Edington CD, Chen WLK, Geishecker E, Kassis T, Soenksen LR, Bhushan BM, Freake D, Kirschner J, Maass C, Tsamandouras N, Valdez J, Cook CD, Parent T, Snyder S, Yu J, ... ... Griffith LG, et al. Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies. Scientific Reports. 8: 4530. PMID 29540740 DOI: 10.1038/S41598-018-22749-0  0.412
2018 Clark AM, Kumar M, Wheeler S, Young C, Venkataramanan R, Stolz D, Griffith L, Lauffenburger DA, Wells A. A model of dormant-emergent metastatic breast cancer progression enabling exploration of biomarker signatures. Molecular & Cellular Proteomics : McP. PMID 29353230 DOI: 10.1074/Mcp.Ra117.000370  0.455
2018 Wright KD, Chadwick E, Rota C, Brown A, Stockdale L, Kieran MW, Ligon K, Goumnerova L, Lauffenburger D, Griffith L, Segal R. PCLN-07. A 3D HYDROGEL CULTURE SYSTEM FACILITATES STUDY OF PRIMARY PEDIATRIC LOW-GRADE GLIOMA CELLS IN VITRO Neuro-Oncology. 20: i156-i156. DOI: 10.1093/Neuonc/Noy059.576  0.481
2017 Beckwitt CH, Clark AM, Wheeler S, Taylor DL, Stolz DB, Griffith L, Wells A. Liver 'organ on a chip'. Experimental Cell Research. PMID 29291400 DOI: 10.1016/J.Yexcr.2017.12.023  0.301
2017 Yoneyama T, Gorry M, Miller MA, Gaither-Davis A, Lin Y, Moss ML, Griffith LG, Lauffenburger DA, Stabile LP, Herman JG, Vujanovic NL. Modification of proteolytic activity matrix analysis (PrAMA) to measure ADAM10 and ADAM17 sheddase activities in cell and tissue lysates. Journal of Cancer. 8: 3916-3932. PMID 29187866 DOI: 10.7150/jca.20779  0.435
2017 Chen WLK, Edington C, Suter E, Yu J, Velazquez JJ, Velazquez JG, Shockley M, Large EM, Venkataramanan R, Hughes DJ, Stokes CL, Trumper DL, Carrier RL, Cirit M, Griffith LG, et al. Integrated Gut/Liver Microphysiological Systems Elucidates Inflammatory Inter-Tissue Crosstalk. Biotechnology and Bioengineering. PMID 28667746 DOI: 10.1002/Bit.26370  0.435
2017 Sarkar U, Ravindra KC, Large E, Young CL, Rivera-Burgos D, Yu J, Cirit M, Hughes DJ, Wishnok JS, Lauffenburger DA, Griffith LG, Tannenbaum SR. Integrated assessment of diclofenac biotransformation, pharmacokinetics, and omics-based toxicity in a 3D human liver-immunocompetent co-culture system. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28450578 DOI: 10.1124/Dmd.116.074005  0.415
2017 Jørgensen H, Hill AS, Beste MT, Kumar MP, Chiswick E, Fedorcsak P, Isaacson KB, Lauffenburger DA, Griffith LG, Qvigstad E. Peritoneal fluid cytokines related to endometriosis in patients evaluated for infertility. Fertility and Sterility. PMID 28433374 DOI: 10.1016/J.Fertnstert.2017.03.013  0.332
2017 Valdez J, Cook CD, Ahrens CC, Wang AJ, Brown A, Kumar M, Stockdale L, Rothenberg D, Renggli K, Gordon E, Lauffenburger D, White F, Griffith L. On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks. Biomaterials. 130: 90-103. PMID 28371736 DOI: 10.1016/J.Biomaterials.2017.03.030  0.55
2017 Cook CD, Hill AS, Guo M, Stockdale L, Papps JP, Isaacson KB, Lauffenburger DA, Griffith LG. Local remodeling of synthetic extracellular matrix microenvironments by co-cultured endometrial epithelial and stromal cells enables long-term dynamic physiological function. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 28317948 DOI: 10.1039/c6ib00245e  0.498
2016 Clark AM, Wheeler SE, Young CL, Stockdale L, Shepard Neiman J, Zhao W, Stolz DB, Venkataramanan R, Lauffenburger D, Griffith L, Wells A. A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties. Lab On a Chip. PMID 27910972 DOI: 10.1039/C6Lc01171C  0.386
2016 Nuschke A, Rodrigues M, Rivera J, Yates C, Whaley D, Stolz D, Griffith L, Wells A. Epidermal Growth Factor Tethered to β-Tricalcium Phosphate Bone Scaffolds via a High-Affinity Binding Peptide Enhances Survival of Human Mesenchymal Stem Cells/Multipotent Stromal Cells in an Immune-Competent Parafascial Implantation Assay in Mice. Stem Cells Translational Medicine. PMID 27400798 DOI: 10.5966/Sctm.2015-0326  0.363
2016 Clark AM, Ma B, Taylor DL, Griffith L, Wells A. Liver metastases: Microenvironments and ex-vivo models. Experimental Biology and Medicine (Maywood, N.J.). PMID 27390264 DOI: 10.1177/1535370216658144  0.341
2016 Miller MA, Oudin MJ, Sullivan RJ, Wang SJ, Meyer AS, Im H, Frederick DT, Tadros J, Griffith LG, Lee H, Weissleder R, Flaherty KT, Gertler FB, Lauffenburger DA. Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance. Cancer Discovery. PMID 26984351 DOI: 10.1158/2159-8290.Cd-15-0933  0.395
2016 Cirit M, Griffith L, Lauffenburger D, Tannenbaum S, Hughes D, Rohatgi G. Human physiome on a chip: A platform for drug discovery and development Toxicology Letters. 258: S191-S192. DOI: 10.1016/J.Toxlet.2016.06.1703  0.437
2015 Yu J, Cilfone NA, Large EM, Sarkar U, Wishnok JS, Tannenbaum SR, Hughes DJ, Lauffenburger DA, Griffith LG, Stokes CL, Cirit M. Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration. Cpt: Pharmacometrics & Systems Pharmacology. 4: 585-94. PMID 26535159 DOI: 10.1002/psp4.12010  0.386
2015 Miller MA, Moss ML, Powell G, Petrovich R, Edwards L, Meyer AS, Griffith LG, Lauffenburger DA. Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain. Scientific Reports. 5: 15150. PMID 26477568 DOI: 10.1038/srep15150  0.406
2014 Nuschke A, Rodrigues M, Stolz DB, Chu CT, Griffith L, Wells A. Human mesenchymal stem cells/multipotent stromal cells consume accumulated autophagosomes early in differentiation. Stem Cell Research & Therapy. 5: 140. PMID 25523618 DOI: 10.1186/Scrt530  0.316
2014 Tan CW, Lee YH, Tan HH, Lau MS, Choolani M, Griffith L, Chan JK. CD26/DPPIV down-regulation in endometrial stromal cell migration in endometriosis. Fertility and Sterility. 102: 167-177.e9. PMID 24825423 DOI: 10.1016/J.Fertnstert.2014.04.001  0.332
2014 Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan R, Griffith LG, Wells A. A microphysiological system model of therapy for liver micrometastases. Experimental Biology and Medicine (Maywood, N.J.). 239: 1170-9. PMID 24821820 DOI: 10.1177/1535370214532596  0.454
2014 Ebrahimkhani MR, Young CL, Lauffenburger DA, Griffith LG, Borenstein JT. Approaches to in vitro tissue regeneration with application for human disease modeling and drug development. Drug Discovery Today. 19: 754-62. PMID 24793141 DOI: 10.1016/J.Drudis.2014.04.017  0.433
2014 Beste MT, Pfäffle-Doyle N, Prentice EA, Morris SN, Lauffenburger DA, Isaacson KB, Griffith LG. Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation. Science Translational Medicine. 6: 222ra16. PMID 24500404 DOI: 10.1126/Scitranslmed.3007988  0.399
2014 Young CL, Griffith LG, Lauffenburger DA. Evaluation of biomolecular metrics in microphysiological systems: Technical challenges associated with multiplex arrays Proceedings of the Ieee Annual Northeast Bioengineering Conference, Nebec. 2014. DOI: 10.1109/NEBEC.2014.6972992  0.334
2013 Wheeler SE, Borenstein JT, Clark AM, Ebrahimkhani MR, Fox IJ, Griffith L, Inman W, Lauffenburger D, Nguyen T, Pillai VC, Prantil-Baun R, Stolz DB, Taylor D, Ulrich T, Venkataramanan R, et al. All-human microphysical model of metastasis therapy. Stem Cell Research & Therapy. 4: S11. PMID 24565274 DOI: 10.1186/Scrt372  0.502
2013 Tsukamoto K, Buck L, Inman W, Griffith L, Kocher O, Krieger M. Challenges in using cultured primary rodent hepatocytes or cell lines to study hepatic HDL receptor SR-BI regulation by its cytoplasmic adaptor PDZK1. Plos One. 8: e69725. PMID 23936087 DOI: 10.1371/Journal.Pone.0069725  0.33
2013 Wells A, Griffith L, Wells JZ, Taylor DP. The dormancy dilemma: quiescence versus balanced proliferation. Cancer Research. 73: 3811-6. PMID 23794703 DOI: 10.1158/0008-5472.Can-13-0356  0.33
2013 Miller MA, Meyer AS, Beste MT, Lasisi Z, Reddy S, Jeng KW, Chen CH, Han J, Isaacson K, Griffith LG, Lauffenburger DA. ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: E2074-83. PMID 23674691 DOI: 10.1073/Pnas.1222387110  0.475
2013 Rodrigues M, Yates CC, Nuschke A, Griffith L, Wells A. The matrikine tenascin-C protects multipotential stromal cells/mesenchymal stem cells from death cytokines such as FasL. Tissue Engineering. Part A. 19: 1972-83. PMID 23541003 DOI: 10.1089/Ten.Tea.2012.0568  0.367
2013 Chen CH, Miller MA, Sarkar A, Beste MT, Isaacson KB, Lauffenburger DA, Griffith LG, Han J. Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis. Journal of the American Chemical Society. 135: 1645-8. PMID 23157326 DOI: 10.1021/Ja307866Z  0.395
2013 Rodrigues M, Blair H, Stockdale L, Griffith L, Wells A. Surface tethered epidermal growth factor protects proliferating and differentiating multipotential stromal cells from FasL-induced apoptosis. Stem Cells (Dayton, Ohio). 31: 104-16. PMID 22948863 DOI: 10.1002/Stem.1215  0.349
2012 Stains CI, Tedford NC, Walkup TC, Lukovi? E, Goguen BN, Griffith LG, Lauffenburger DA, Imperiali B. Interrogating signaling nodes involved in cellular transformations using kinase activity probes. Chemistry & Biology. 19: 210-7. PMID 22365604 DOI: 10.1016/J.Chembiol.2011.11.012  0.379
2012 Hang TC, Lauffenburger DA, Griffith LG, Stolz DB. Lipids promote survival, proliferation, and maintenance of differentiation of rat liver sinusoidal endothelial cells in vitro. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G375-88. PMID 22075778 DOI: 10.1152/ajpgi.00288.2011  0.427
2011 Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, ... Griffith LG, et al. ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein. The Journal of Biological Chemistry. 286: 40443-51. PMID 21956108 DOI: 10.1074/Jbc.M111.280495  0.417
2011 Wu S, Wells A, Griffith LG, Lauffenburger DA. Controlling multipotent stromal cell migration by integrating "course-graining" materials and "fine-tuning" small molecules via decision tree signal-response modeling. Biomaterials. 32: 7524-31. PMID 21782235 DOI: 10.1016/J.Biomaterials.2011.06.050  0.494
2011 Chen CH, Sarkar A, Song YA, Miller MA, Kim SJ, Griffith LG, Lauffenburger DA, Han J. Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator. Journal of the American Chemical Society. 133: 10368-71. PMID 21671557 DOI: 10.1021/Ja2036628  0.372
2011 Peyton SR, Kalcioglu ZI, Cohen JC, Runkle AP, Van Vliet KJ, Lauffenburger DA, Griffith LG. Marrow-derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness. Biotechnology and Bioengineering. 108: 1181-93. PMID 21449030 DOI: 10.1002/Bit.23027  0.679
2011 Miller MA, Barkal L, Jeng K, Herrlich A, Moss M, Griffith LG, Lauffenburger DA. Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 422-38. PMID 21180771 DOI: 10.1039/c0ib00083c  0.402
2011 Williams CM, Mehta G, Peyton SR, Zeiger AS, Van Vliet KJ, Griffith LG. Autocrine-controlled formation and function of tissue-like aggregates by primary hepatocytes in micropatterned hydrogel arrays. Tissue Engineering. Part A. 17: 1055-68. PMID 21121876 DOI: 10.1089/Ten.Tea.2010.0398  0.623
2010 Cosgrove BD, Alexopoulos LG, Hang TC, Hendriks BS, Sorger PK, Griffith LG, Lauffenburger DA. Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation. Molecular Biosystems. 6: 1195-206. PMID 20361094 DOI: 10.1039/B926287C  0.416
2009 Cosgrove BD, Alexopoulos LG, Saez-Rodriguez J, Griffith LG, Lauffenburger DA. A multipathway phosphoproteomic signaling network model of idiosyncratic drug- and inflammatory cytokine-induced toxicity in human hepatocytes. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 5452-5. PMID 19964679 DOI: 10.1109/IEMBS.2009.5334019  0.421
2009 Platt MO, Wilder CL, Wells A, Griffith LG, Lauffenburger DA. Multipathway kinase signatures of multipotent stromal cells are predictive for osteogenic differentiation: tissue-specific stem cells. Stem Cells (Dayton, Ohio). 27: 2804-14. PMID 19750537 DOI: 10.1002/Stem.215  0.456
2009 Pritchard JR, Cosgrove BD, Hemann MT, Griffith LG, Wands JR, Lauffenburger DA. Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death. Molecular Cancer Therapeutics. 8: 2183-92. PMID 19671754 DOI: 10.1158/1535-7163.Mct-08-1203  0.432
2009 Platt MO, Roman AJ, Wells A, Lauffenburger DA, Griffith LG. Sustained epidermal growth factor receptor levels and activation by tethered ligand binding enhances osteogenic differentiation of multi-potent marrow stromal cells. Journal of Cellular Physiology. 221: 306-17. PMID 19544388 DOI: 10.1002/Jcp.21854  0.447
2009 Cosgrove BD, King BM, Hasan MA, Alexopoulos LG, Farazi PA, Hendriks BS, Griffith LG, Sorger PK, Tidor B, Xu JJ, Lauffenburger DA. Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity. Toxicology and Applied Pharmacology. 237: 317-30. PMID 19362101 DOI: 10.1016/J.Taap.2009.04.002  0.389
2008 Cosgrove BD, Cheng C, Pritchard JR, Stolz DB, Lauffenburger DA, Griffith LG. An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha. Hepatology (Baltimore, Md.). 48: 276-88. PMID 18536058 DOI: 10.1002/hep.22335  0.366
2008 Patterson TE, Kumagai K, Griffith L, Muschler GF. Cellular strategies for enhancement of fracture repair. Journal of Bone and Joint Surgery, American Volume. 90: 111-119. PMID 18292365 DOI: 10.2106/Jbjs.G.01572  0.353
2008 Iyer AK, Tran KT, Griffith L, Wells A. Cell surface restriction of EGFR by a tenascin cytotactin-encoded EGF-like repeat is preferential for motility-related signaling. Journal of Cellular Physiology. 214: 504-12. PMID 17708541 DOI: 10.1002/Jcp.21232  0.334
2008 Cosgrove BD, Griffith LG, Lauffenburger DA. Fusing Tissue Engineering and Systems Biology Toward Fulfilling Their Promise Cellular and Molecular Bioengineering. 1: 33-41. DOI: 10.1007/S12195-008-0007-9  0.37
2007 Zugates GT, Tedford NC, Zumbuehl A, Jhunjhunwala S, Kang CS, Griffith LG, Lauffenburger DA, Langer R, Anderson DG. Gene delivery properties of end-modified poly(beta-amino ester)s. Bioconjugate Chemistry. 18: 1887-96. PMID 17929884 DOI: 10.1021/Bc7002082  0.543
2007 Yates C, Shepard CR, Papworth G, Dash A, Beer Stolz D, Tannenbaum S, Griffith L, Wells A. Novel three-dimensional organotypic liver bioreactor to directly visualize early events in metastatic progression. Advances in Cancer Research. 97: 225-46. PMID 17419948 DOI: 10.1016/S0065-230X(06)97010-9  0.329
2007 Green J, Zugates G, Tedford N, Huang Y, Griffith L, Lauffenburger D, Sawicki J, Langer R, Anderson D. Inside Front Cover: Combinatorial Modification of Degradable Polymers Enables Transfection of Human Cells Comparable to Adenovirus (Adv. Mater. 19/2007) Advanced Materials. 19: NA-NA. DOI: 10.1002/Adma.200790075  0.516
2007 Green JJ, Zugates GT, Tedford NC, Huang YH, Griffith LG, Lauffenburger DA, Sawicki JA, Langer R, Anderson DG. Combinatorial modification of degradable polymers enables transfection of human cells comparable to adenovirus Advanced Materials. 19: 2836-2842. DOI: 10.1002/Adma.200700371  0.582
2006 Miller-Jensen K, Janes KA, Wong YL, Griffith LG, Lauffenburger DA. Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis. Journal of Cell Science. 119: 3788-98. PMID 16940353 DOI: 10.1242/Jcs.03102  0.421
2006 Wells A, Harms B, Iwabu A, Koo L, Smith K, Griffith L, Lauffenburger DA. Motility signaled from the EGF receptor and related systems Methods in Molecular Biology (Clifton, N.J.). 327: 159-177. PMID 16780220 DOI: 10.1385/1-59745-012-X:159  0.487
2006 Griffith LG, Swartz MA. Capturing complex 3D tissue physiology in vitro. Nature Reviews. Molecular Cell Biology. 7: 211-24. PMID 16496023 DOI: 10.1038/nrm1858  0.382
2006 Griffith L, Swartz M, Tranquillo R. Education for careers in tissue engineering and regenerative medicine. Annals of Biomedical Engineering. 34: 265-9. PMID 16450189 DOI: 10.1007/S10439-005-9038-8  0.397
2006 Tedford N, Fang J, Domansky K, Griffith LG, Lauffenburger DA. 396. Quantitative Analysis of Non-Viral Gene Therapy in a Three-Dimensional Liver Bioreactor Molecular Therapy. 13: S151-S152. DOI: 10.1016/j.ymthe.2006.08.458  0.34
2005 Varga CM, Tedford NC, Thomas M, Klibanov AM, Griffith LG, Lauffenburger DA. Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes. Gene Therapy. 12: 1023-32. PMID 15815703 DOI: 10.1038/Sj.Gt.3302495  0.4
2004 Lu H, Koo LY, Wang WM, Lauffenburger DA, Griffith LG, Jensen KF. Microfluidic shear devices for quantitative analysis of cell adhesion. Analytical Chemistry. 76: 5257-64. PMID 15362881 DOI: 10.1021/Ac049837T  0.454
2004 Tran KT, Griffith L, Wells A. Extracellular matrix signaling through growth factor receptors during wound healing. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 12: 262-8. PMID 15225204 DOI: 10.1111/J.1067-1927.2004.012302.X  0.324
2002 Koo LY, Irvine DJ, Mayes AM, Lauffenburger DA, Griffith LG. Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus. Journal of Cell Science. 115: 1423-33. PMID 11896190  0.592
2002 Irvine DJ, Hue KA, Mayes AM, Griffith LG. Simulations of cell-surface integrin binding to nanoscale-clustered adhesion ligands. Biophysical Journal. 82: 120-32. PMID 11751301 DOI: 10.1016/S0006-3495(02)75379-4  0.461
2001 Irvine DJ, Ruzette AV, Mayes AM, Griffith LG. Nanoscale clustering of RGD peptides at surfaces using comb polymers. 2. Surface segregation of comb polymers in polylactide. Biomacromolecules. 2: 545-56. PMID 11749219 DOI: 10.1021/Bm015510F  0.469
2001 Irvine DJ, Mayes AM, Griffith LG. Nanoscale clustering of RGD peptides at surfaces using Comb polymers. 1. Synthesis and characterization of Comb thin films. Biomacromolecules. 2: 85-94. PMID 11749159 DOI: 10.1021/Bm005584B  0.458
2001 Swindle CS, Tran KT, Johnson TD, Banerjee P, Mayes AM, Griffith L, Wells A. Epidermal growth factor (EGF)-like repeats of human tenascin-C as ligands for EGF receptor. The Journal of Cell Biology. 154: 459-68. PMID 11470832 DOI: 10.1083/Jcb.200103103  0.326
2001 Lauffenburger DA, Griffith LG. Who's got pull around here? Cell organization in development and tissue engineering. Proceedings of the National Academy of Sciences of the United States of America. 98: 4282-4. PMID 11296276 DOI: 10.1073/pnas.081083698  0.407
2000 Zandstra PW, Le HV, Daley GQ, Griffith LG, Lauffenburger DA. Leukemia inhibitory factor (LIF) concentration modulates embryonic stem cell self-renewal and differentiation independently of proliferation. Biotechnology and Bioengineering. 69: 607-17. PMID 10918135 DOI: 10.1002/1097-0290(20000920)69:6<607::Aid-Bit4>3.0.Co;2-F  0.683
2000 Maheshwari G, Brown G, Lauffenburger DA, Wells A, Griffith LG. Cell adhesion and motility depend on nanoscale RGD clustering. Journal of Cell Science. 113: 1677-86. PMID 10769199  0.463
2000 Banerjee P, Irvine DJ, Mayes AM, Griffith LG. Polymer latexes for cell-resistant and cell-interactive surfaces. Journal of Biomedical Materials Research. 50: 331-9. PMID 10737874 DOI: 10.1002/(Sici)1097-4636(20000605)50:3<331::Aid-Jbm6>3.0.Co;2-T  0.487
1999 Maheshwari G, Wells A, Griffith LG, Lauffenburger DA. Biophysical integration of effects of epidermal growth factor and fibronectin on fibroblast migration. Biophysical Journal. 76: 2814-23. PMID 10233097 DOI: 10.1016/S0006-3495(99)77435-7  0.442
1998 Kim SS, Utsunomiya H, Koski JA, Wu BM, Cima MJ, Sohn J, Mukai K, Griffith LG, Vacanti JP. Survival and function of hepatocytes on a novel three-dimensional synthetic biodegradable polymer scaffold with an intrinsic network of channels. Annals of Surgery. 228: 8-13. PMID 9671060 DOI: 10.1097/00000658-199807000-00002  0.414
1998 Irvine DJ, Mayes AM, Satija SK, Barker JG, Sofia-Allgor SJ, Griffith LG. Comparison of tethered star and linear poly(ethylene oxide) for control of biomaterials surface properties. Journal of Biomedical Materials Research. 40: 498-509. PMID 9570083 DOI: 10.1002/(Sici)1097-4636(19980605)40:3<498::Aid-Jbm21>3.0.Co;2-E  0.435
1998 Hobbs SK, Monsky WL, Yuan F, Roberts WG, Griffith L, Torchilin VP, Jain RK. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proceedings of the National Academy of Sciences of the United States of America. 95: 4607-12. PMID 9539785 DOI: 10.1073/Pnas.95.8.4607  0.386
1998 Mayes AM, Irvine DJ, Griffith LG. Tailoring polymer surfaces for controlled cell behavior Materials Research Society Symposium - Proceedings. 530: 73-84. DOI: 10.1557/Proc-530-73  0.457
1997 Griffith LG, Wu B, Cima MJ, Powers MJ, Chaignaud B, Vacanti JP. In vitro organogenesis of liver tissue Annals of the New York Academy of Sciences. 831: 382-397. PMID 9616729 DOI: 10.1111/J.1749-6632.1997.Tb52212.X  0.479
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