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Year Citation  Score
2021 Karzbrun E, Khankhel AH, Megale HC, Glasauer SMK, Wyle Y, Britton G, Warmflash A, Kosik KS, Siggia ED, Shraiman BI, Streichan SJ. Human neural tube morphogenesis in vitro by geometric constraints. Nature. 599: 268-272. PMID 34707290 DOI: 10.1038/s41586-021-04026-9  0.497
2019 Gross M, Sánchez-Velasco E, Siggia ED. Spin-wave velocity and susceptibility for the two-dimensional Heisenberg antiferromagnet. Physical Review. B, Condensed Matter. 40: 11328-11330. PMID 9991708 DOI: 10.1103/Physrevb.40.11328  0.303
2019 Gross M, Sánchez-Velasco E, Siggia E. Ground-state properties of the two-dimensional antiferromagnetic Heisenberg model. Physical Review. B, Condensed Matter. 39: 2484-2493. PMID 9948488 DOI: 10.1103/Physrevb.39.2484  0.305
2013 François P, Voisinne G, Siggia ED, Altan-Bonnet G, Vergassola M. Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism. Proceedings of the National Academy of Sciences of the United States of America. 110: E888-97. PMID 23431198 DOI: 10.1073/Pnas.1300752110  0.595
2009 Morozov AV, Fortney K, Gaykalova DA, Studitsky VM, Widom J, Siggia ED. Using DNA mechanics to predict in vitro nucleosome positions and formation energies. Nucleic Acids Research. 37: 4707-22. PMID 19509309 DOI: 10.1093/Nar/Gkp475  0.511
2007 Morozov AV, Siggia ED. Connecting protein structure with predictions of regulatory sites. Proceedings of the National Academy of Sciences of the United States of America. 104: 7068-73. PMID 17438293 DOI: 10.1073/Pnas.0701356104  0.517
2006 Sinha S, Liang Y, Siggia E. Stubb: a program for discovery and analysis of cis-regulatory modules. Nucleic Acids Research. 34: W555-9. PMID 16845069 DOI: 10.1093/Nar/Gkl224  0.485
2005 Morozov AV, Havranek JJ, Baker D, Siggia ED. Protein-DNA binding specificity predictions with structural models. Nucleic Acids Research. 33: 5781-98. PMID 16246914 DOI: 10.1093/Nar/Gki875  0.566
2005 Sinha S, Siggia ED. Sequence turnover and tandem repeats in cis-regulatory modules in drosophila. Molecular Biology and Evolution. 22: 874-85. PMID 15659554 DOI: 10.1093/Molbev/Msi090  0.496
2004 Sinha S, Schroeder MD, Unnerstall U, Gaul U, Siggia ED. Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila. Bmc Bioinformatics. 5: 129. PMID 15357878 DOI: 10.1186/1471-2105-5-129  0.486
2003 Sinha S, van Nimwegen E, Siggia ED. A probabilistic method to detect regulatory modules. Bioinformatics (Oxford, England). 19: i292-301. PMID 12855472 DOI: 10.1093/Bioinformatics/Btg1040  0.469
2001 Bussemaker HJ, Li H, Siggia ED. Regulatory element detection using correlation with expression. Nature Genetics. 27: 167-71. PMID 11175784 DOI: 10.1038/84792  0.589
2000 Bussemaker HJ, Li H, Siggia ED. Building a dictionary for genomes: identification of presumptive regulatory sites by statistical analysis. Proceedings of the National Academy of Sciences of the United States of America. 97: 10096-100. PMID 10944202 DOI: 10.1073/Pnas.180265397  0.594
2000 Shraiman BI, Siggia ED. Scalar turbulence Nature. 405: 639-46. PMID 10864314 DOI: 10.1038/35015000  0.538
1999 Pumir A, Shraiman BI, Siggia ED. Turbulent mixing of a passive scalar Physica a: Statistical Mechanics and Its Applications. 263: 95-103. DOI: 10.1016/S0378-4371(98)00532-9  0.602
1998 Mydlarski L, Pumir A, Shraiman BI, Siggia ED, Warhaft Z. Structures and Multipoint Correlators for Turbulent Advection: Predictions and Experiments Physical Review Letters. 81: 4373-4376. DOI: 10.1103/Physrevlett.81.4373  0.595
1998 Shraiman BI, Siggia ED. Anomalous scaling for a passive scalar near the Batchelor limit Physical Review E. 57: 2965-2977. DOI: 10.1103/Physreve.57.2965  0.593
1997 Pumir A, Shraiman BI, Siggia ED. Perturbation theory for the δ-correlated model of passive scalar advection near the Batchelor limit Physical Review E. 55: R1263-R1266. DOI: 10.1103/Physreve.55.R1263  0.568
1996 Shraiman BI, Siggia ED. Symmetry and Scaling of Turbulent Mixing. Physical Review Letters. 77: 2463-2466. PMID 10061960 DOI: 10.1103/Physrevlett.77.2463  0.611
1996 Shraiman BI, Siggia ED. High Rayleigh number convection and passive scalar mixing Physica D: Nonlinear Phenomena. 97: 286-290. DOI: 10.1016/0167-2789(96)00075-9  0.583
1994 Shraiman BI, Siggia ED. Lagrangian path integrals and fluctuations in random flow. Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 49: 2912-2927. PMID 9961557 DOI: 10.1103/Physreve.49.2912  0.57
1994 Siggia ED. High Rayleigh Number Convection Annual Review of Fluid Mechanics. 26: 137-168. DOI: 10.1146/Annurev.Fl.26.010194.001033  0.302
1992 Shraiman BI, Siggia ED. Excitation spectrum of the spiral state of a doped antiferromagnet. Physical Review. B, Condensed Matter. 46: 8305-8311. PMID 10002592 DOI: 10.1103/Physrevb.46.8305  0.591
1992 Pumir A, Shraiman BI, Siggia ED. Vortex morphology and Kelvin's theorem. Physical Review. A. 45: R5351-R5354. PMID 9907727 DOI: 10.1103/Physreva.45.R5351  0.578
1992 Pumir A, Siggia ED. Singular solutions to the 3D axisymmetric incompressible Euler equations Physica D: Nonlinear Phenomena. 61: 240-245. DOI: 10.1016/0167-2789(92)90167-L  0.303
1991 Pumir A, Shraiman BI, Siggia ED. Exponential tails and random advection. Physical Review Letters. 66: 2984-2987. PMID 10043669 DOI: 10.1103/Physrevlett.66.2984  0.542
1990 Shraiman BI, Siggia ED. Mobile vacancy in a quantum antiferromagnet: Effective Hamiltonian. Physical Review. B, Condensed Matter. 42: 2485-2500. PMID 9995698 DOI: 10.1103/Physrevb.42.2485  0.555
1990 Elser V, Huse DA, Shraiman BI, Siggia ED. Ground state of a mobile vacancy in a quantum antiferromagnet: Small-cluster study. Physical Review. B, Condensed Matter. 41: 6715-6723. PMID 9992924 DOI: 10.1103/Physrevb.41.6715  0.565
1990 Frenkel DM, Gooding RJ, Shraiman BI, Siggia ED. Ground-state properties of a single oxygen hole in a CuO2 plane. Physical Review. B, Condensed Matter. 41: 350-370. PMID 9992772 DOI: 10.1103/Physrevb.41.350  0.577
1990 Shraiman BI, Siggia ED. Heat transport in high-Rayleigh-number convection. Physical Review. A. 42: 3650-3653. PMID 9904456 DOI: 10.1103/Physreva.42.3650  0.566
1989 Shraiman BI, Siggia ED. Spiral phase of a doped quantum antiferromagnet. Physical Review Letters. 62: 1564-1567. PMID 10039706 DOI: 10.1103/Physrevlett.62.1564  0.593
1989 Shraiman BI, Siggia ED. Mean-field theory for vacancies in a quantum antiferromagnet. Physical Review. B, Condensed Matter. 40: 9162-9166. PMID 9991405 DOI: 10.1103/Physrevb.40.9162  0.587
1989 Shraiman BI, Siggia ED. SPIRAL PHASES OF DOPED ANTIFERROMAGNETS International Journal of Modern Physics B. 3: 1905-1911. DOI: 10.1142/S0217979289001238  0.536
1988 Shraiman BI, Siggia ED. Mobile vacancies in a quantum Heisenberg antiferromagnet. Physical Review Letters. 61: 467-470. PMID 10039340 DOI: 10.1103/Physrevlett.61.467  0.582
1988 Shraiman BI, Siggia ED. Two-particle excitations in antiferromagnetic insulators. Physical Review Letters. 60: 740-743. PMID 10038634 DOI: 10.1103/Physrevlett.60.740  0.57
1983 Ostlund S, Pandit R, Rand D, Schellnhuber HJ, Siggia ED. One-Dimensional Schrödinger Equation with an Almost Periodic Potential Physical Review Letters. 50: 1873-1876. DOI: 10.1103/Physrevlett.50.1873  0.305
1982 Ruckenstein AE, Siggia ED. Surface magnetic relaxation rates in spin-polarized hydrogen Physical Review B. 25: 6031-6034. DOI: 10.1103/Physrevb.25.6031  0.628
1981 Siggia ED, Ruckenstein AE. Hydrodynamics of the condensed phases of spin-polarized atomic hydrogen Physical Review B. 23: 3580-3583. DOI: 10.1103/Physrevb.23.3580  0.643
1981 Siggia ED. Numerical study of small-scale intermittency in three-dimensional turbulence Journal of Fluid Mechanics. 107: 375. DOI: 10.1017/S002211208100181X  0.32
1981 Aref H, Siggia ED. Evolution and breakdown of a vortex street in two dimensions Journal of Fluid Mechanics. 109: 435-463. DOI: 10.1017/S0022112081001158  0.617
1981 Ruckenstein AE, Siggia E. Longitudinal and transverse relaxation in spin polarized hydrogen Physica B+C. 107: 519. DOI: 10.1016/0378-4363(81)90562-3  0.628
1980 Siggia ED, Aref H. SCALIAG AND STRUCTURES IN FULLY TURBUI-ENT FLOWS Annals of the New York Academy of Sciences. 357: 368-376. DOI: 10.1111/J.1749-6632.1980.Tb29704.X  0.57
1980 Siggia ED, Ruckenstein AE. Bose Condensation in Spin-Polarized Atomic Hydrogen Physical Review Letters. 44: 1423-1426. DOI: 10.1051/Jphyscol:1980703  0.642
1980 Siggia ED, Ruckenstein AE. BOSE CONDENSATION IN SPIN POLARIZED ATOMIC HYDROGEN Le Journal De Physique Colloques. 41: C7-15-C7-18. DOI: 10.1051/jphyscol:1980703  0.588
1980 Aref H, Siggia ED. Vortex dynamics of the two-dimensional turbulent shear layer Journal of Fluid Mechanics. 100: 705-737. DOI: 10.1017/S0022112080001371  0.602
1976 Hohenberg PC, Siggia ED, Halperin BI. Density-correlation function for liquid helium near Tλ in the symmetric planar-spin model Physical Review B. 14: 2865-2874. DOI: 10.1103/Physrevb.14.2865  0.316
1973 Martin PC, Siggia ED, Rose HA. Statistical dynamics of classical systems Physical Review A. 8: 423-437. DOI: 10.1103/Physreva.8.423  0.399
Low-probability matches (unlikely to be authored by this person)
1977 Siggia ED, Nelson DR. Tricritical dynamics near four dimensions Physical Review B. 15: 1427-1444. DOI: 10.1103/Physrevb.15.1427  0.297
1983 Siggia ED. A universal transition from quasi-periodicity to chaos Physica D: Nonlinear Phenomena. 7: 302. DOI: 10.1016/0167-2789(83)90133-1  0.296
1992 Pumir A, Siggia ED. Development of singular solutions to the axisymmetric Euler equations Physics of Fluids a: Fluid Dynamics. 4: 1472-1491. DOI: 10.1063/1.858422  0.294
2012 François P, Siggia ED. Phenotypic models of evolution and development: geometry as destiny. Current Opinion in Genetics & Development. 22: 627-33. PMID 23026724 DOI: 10.1016/J.Gde.2012.09.001  0.29
1987 Pumir A, Siggia ED. Vortex dynamics and the existence of solutions to the Navier–Stokes equations Physics of Fluids. 30: 1606. DOI: 10.1063/1.866226  0.289
1992 Pumir A, Siggia ED. Finite-time singularities in the axisymmetric three-dimension Euler equations. Physical Review Letters. 68: 1511-1514. PMID 10045150 DOI: 10.1103/Physrevlett.68.1511  0.289
1983 Zippelius A, Siggia ED. Stability of finite-amplitude convection Physics of Fluids. 26: 2905-2915. DOI: 10.1063/1.864055  0.287
1982 Huse DA, Siggia ED. The density distribution of a weakly interacting bose gas in an external potential Journal of Low Temperature Physics. 46: 137-149. DOI: 10.1007/Bf00655448  0.287
1985 Siggia ED. Collapse and amplification of a vortex filament Physics of Fluids. 28: 794. DOI: 10.1063/1.865047  0.286
1980 Tremblay A, Siggia ED, Arai M. Fluctuations about hydrodynamic nonequilibrium steady states Physics Letters A. 76: 57-60. DOI: 10.1016/0375-9601(80)90146-2  0.286
2009 Gertz J, Siggia ED, Cohen BA. Analysis of combinatorial cis-regulation in synthetic and genomic promoters. Nature. 457: 215-8. PMID 19029883 DOI: 10.1038/Nature07521  0.285
1981 Siggia ED, Zippelius A. Pattern selection in rayleigh-Bénard convection near threshold Physical Review Letters. 47: 835-838. DOI: 10.1103/Physrevlett.47.835  0.285
2002 Rajewsky N, Socci ND, Zapotocky M, Siggia ED. The evolution of DNA regulatory regions for proteo-gamma bacteria by interspecies comparisons. Genome Research. 12: 298-308. PMID 11827949 DOI: 10.1101/Gr.207502  0.285
1983 Cross MC, Daniels PG, Hohenberg PC, Siggia ED. PHASE-WINDING SOLUTIONS IN A FINITE CONTAINER ABOVE THE CONVECTIVE THRESHOLD Journal of Fluid Mechanics. 127: 155-183. DOI: 10.1017/S0022112083002670  0.283
1978 Kerr RM, Siggia ED. Cascade model of fully developed turbulence Journal of Statistical Physics. 19: 543-552. DOI: 10.1007/Bf01011698  0.282
2008 Siggia ED. Developmental regulatory bits. Molecular Systems Biology. 4: 226. PMID 18985026 DOI: 10.1038/Msb.2008.64  0.281
1983 Siggia E. Onset of turbulent convection in large cells Physica a: Statistical Mechanics and Its Applications. 118: 335. DOI: 10.1016/0378-4371(83)90201-7  0.28
1976 Hohenberg PC, Aharony A, Halperin BI, Siggia ED. Two-scale-factor universality and the renormalization group Physical Review B. 13: 2986-2996. DOI: 10.1103/Physrevb.13.2986  0.28
1989 Ercolani N, Siggia ED. Painlevé property and geometry Physica D: Nonlinear Phenomena. 34: 303-346. DOI: 10.1016/0167-2789(89)90259-5  0.277
2002 Rajewsky N, Vergassola M, Gaul U, Siggia ED. Computational detection of genomic cis-regulatory modules applied to body patterning in the early Drosophila embryo. Bmc Bioinformatics. 3: 30. PMID 12398796 DOI: 10.1186/1471-2105-3-30  0.276
2005 Siggia ED. Computational methods for transcriptional regulation. Current Opinion in Genetics & Development. 15: 214-21. PMID 15797205 DOI: 10.1016/J.Gde.2005.02.004  0.275
1985 Siggia ED, Pumir A. Incipient singularities in the Navier-Stokes equations. Physical Review Letters. 55: 1749-1752. PMID 10031913 DOI: 10.1103/Physrevlett.55.1749  0.273
1994 Holzer M, Siggia ED. Turbulent mixing of a passive scalar Physics of Fluids. 6: 1820-1837. DOI: 10.1063/1.868243  0.273
2006 Ligr M, Siddharthan R, Cross FR, Siggia ED. Gene expression from random libraries of yeast promoters. Genetics. 172: 2113-22. PMID 16415362 DOI: 10.1534/Genetics.105.052688  0.271
1981 Siggia ED. Invariants for the one-point vorticity and strain rate correlation functions Physics of Fluids. 24: 1934. DOI: 10.1063/1.863289  0.271
1983 Ostlund S, Rand D, Sethna J, Siggia E. Universal properties of the transition from quasi-periodicity to chaos in dissipative systems Physica D: Nonlinear Phenomena. 8: 303-342. DOI: 10.1016/0167-2789(83)90229-4  0.27
2010 Charvin G, Oikonomou C, Siggia ED, Cross FR. Origin of irreversibility of cell cycle start in budding yeast. Plos Biology. 8: e1000284. PMID 20087409 DOI: 10.1371/Journal.Pbio.1000284  0.27
2004 Schroeder MD, Pearce M, Fak J, Fan H, Unnerstall U, Emberly E, Rajewsky N, Siggia ED, Gaul U. Transcriptional control in the segmentation gene network of Drosophila. Plos Biology. 2: E271. PMID 15340490 DOI: 10.1371/Journal.Pbio.0020271  0.269
2007 François P, Hakim V, Siggia ED. Deriving structure from evolution: metazoan segmentation. Molecular Systems Biology. 3: 154. PMID 18091725 DOI: 10.1038/Msb4100192  0.268
2002 Li H, Rhodius V, Gross C, Siggia ED. Identification of the binding sites of regulatory proteins in bacterial genomes. Proceedings of the National Academy of Sciences of the United States of America. 99: 11772-7. PMID 12181488 DOI: 10.1073/Pnas.112341999  0.268
2016 Rothschild JB, Tsimiklis P, Siggia ED, François P. Predicting Ancestral Segmentation Phenotypes from Drosophila to Anopheles Using In Silico Evolution. Plos Genetics. 12: e1006052. PMID 27227405 DOI: 10.1371/Journal.Pgen.1006052  0.268
2003 Mwangi MM, Siggia ED. Genome wide identification of regulatory motifs in Bacillus subtilis. Bmc Bioinformatics. 4: 18. PMID 12749771 DOI: 10.1186/1471-2105-4-18  0.266
1980 Ambegaokar V, Halperin BI, Nelson DR, Siggia ED. Dynamics of superfluid films Physical Review B. 21: 1806-1826. DOI: 10.1103/Physrevb.21.1806  0.266
2005 Siddharthan R, Siggia ED, van Nimwegen E. PhyloGibbs: a Gibbs sampling motif finder that incorporates phylogeny. Plos Computational Biology. 1: e67. PMID 16477324 DOI: 10.1371/Journal.Pcbi.0010067  0.265
2002 Swain PS, Elowitz MB, Siggia ED. Intrinsic and extrinsic contributions to stochasticity in gene expression. Proceedings of the National Academy of Sciences of the United States of America. 99: 12795-800. PMID 12237400 DOI: 10.1073/Pnas.162041399  0.264
2003 Emberly E, Rajewsky N, Siggia ED. Conservation of regulatory elements between two species of Drosophila. Bmc Bioinformatics. 4: 57. PMID 14629780 DOI: 10.1186/1471-2105-4-57  0.264
1990 Pumir A, Siggia E. Collapsing solutions to the 3‐D Euler equations Physics of Fluids a: Fluid Dynamics. 2: 220-241. DOI: 10.1063/1.857824  0.262
2009 Bai L, Charvin G, Siggia E, Cross F. Nucleosome Depleted Region In Promoter Improves Robustness In Gene Expression Biophysical Journal. 96: 567a. DOI: 10.1016/J.Bpj.2008.12.3715  0.262
1980 Cross MC, Daniels PG, Hohenberg PC, Siggia ED. Effect of distant sidewalls on wave-number selection in rayleigh-bénard convection Physical Review Letters. 45: 898-901. DOI: 10.1103/Physrevlett.45.898  0.262
2003 Siggia ED. Decoding the Genome Annales Henri Poincaré. 4: 663-666. DOI: 10.1007/S00023-003-0950-X  0.262
2006 Bean JM, Siggia ED, Cross FR. Coherence and timing of cell cycle start examined at single-cell resolution. Molecular Cell. 21: 3-14. PMID 16387649 DOI: 10.1016/J.Molcel.2005.10.035  0.262
1981 Siggia ED. Point-vortex simulation of the inverse energy cascade in two-dimensional turbulence Physics of Fluids. 24: 171. DOI: 10.1063/1.863225  0.26
1995 Marko JF, Siggia ED. Statistical mechanics of supercoiled DNA Physical Review E. 52: 2912-2938. DOI: 10.1103/Physreve.52.2912  0.26
1992 Dombre T, Pumir A, Siggia ED. On the interface dynamics for convention in porous media Physica D: Nonlinear Phenomena. 57: 311-329. DOI: 10.1016/0167-2789(92)90005-8  0.259
1981 Tremblay AS, Arai M, Siggia ED. Erratum: Fluctuations about simple nonequilibrium steady states Physical Review A. 24: 1655-1656. DOI: 10.1103/Physreva.24.1655.3  0.259
2010 Bai L, Charvin G, Siggia ED, Cross FR. Nucleosome-depleted regions in cell-cycle-regulated promoters ensure reliable gene expression in every cell cycle. Developmental Cell. 18: 544-55. PMID 20412770 DOI: 10.1016/J.Devcel.2010.02.007  0.259
1981 Tremblay A-S, Arai M, Siggia ED. Fluctuations about simple nonequilibrium steady states Physical Review A. 23: 1451-1480. DOI: 10.1103/Physreva.23.1451  0.259
1977 Siggia ED. Origin of intermittency in fully developed turbulence Physical Review A. 15: 1730-1750. DOI: 10.1103/Physreva.15.1730  0.258
1975 Siggia ED. Critical dynamics of kinetic Ising models in four dimensions Physical Review B. 11: 4736-4736. DOI: 10.1103/Physrevb.11.4736  0.256
2005 Bean JM, Siggia ED, Cross FR. High functional overlap between MluI cell-cycle box binding factor and Swi4/6 cell-cycle box binding factor in the G1/S transcriptional program in Saccharomyces cerevisiae. Genetics. 171: 49-61. PMID 15965243 DOI: 10.1534/Genetics.105.044560  0.255
2000 Isambert H, Siggia ED. Modeling RNA folding paths with pseudoknots: application to hepatitis delta virus ribozyme. Proceedings of the National Academy of Sciences of the United States of America. 97: 6515-20. PMID 10823910 DOI: 10.1073/Pnas.110533697  0.254
1984 Sethna JP, Siggia ED. Universal transition in a dynamical system forced at two incommensurate frequencies Physica D: Nonlinear Phenomena. 11: 193-211. DOI: 10.1016/0167-2789(84)90443-3  0.254
2008 François P, Siggia ED. A case study of evolutionary computation of biochemical adaptation. Physical Biology. 5: 026009. PMID 18577806 DOI: 10.1088/1478-3975/5/2/026009  0.253
2009 Francois P, Vonica A, Brivanlou AH, Siggia ED. Scaling of BMP gradients in Xenopus embryos. Nature. 461: E1; discussion E2. PMID 19736667 DOI: 10.1038/Nature08305  0.25
2012 Warmflash A, Siggia ED, Brivanlou AH. Signaling dynamics and embryonic development. Cell Cycle (Georgetown, Tex.). 11: 3529-30. PMID 22935712 DOI: 10.4161/Cc.21964  0.249
2000 Siggia ED, Lippincott-Schwartz J, Bekiranov S. Diffusion in inhomogeneous media: Theory and simulations applied to whole cell photobleach recovery Biophysical Journal. 79: 1761-1770. PMID 11023884 DOI: 10.1016/S0006-3495(00)76428-9  0.248
2009 Charvin G, Cross FR, Siggia ED. Forced periodic expression of G1 cyclins phase-locks the budding yeast cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 106: 6632-7. PMID 19346485 DOI: 10.1073/Pnas.0809227106  0.247
1976 Halperin BI, Hohenberg PC, Siggia ED. Renormalization-group treatment of the critical dynamics of superfluid helium, the isotropic antiferromagnet, and the easy-plane ferromagnet Physical Review B. 13: 1299-1328. DOI: 10.1103/Physrevb.13.1299  0.246
1979 Siggia ED. Hydrodynamic stability of an evolving vortex ring in a counterflow Journal of Low Temperature Physics. 36: 293-300. DOI: 10.1007/Bf00118706  0.245
1994 Marko JF, Siggia ED. Bending and twisting elasticity of DNA Macromolecules. 27: 981-988. DOI: 10.1021/Ma00082A015  0.245
2002 Elowitz MB, Levine AJ, Siggia ED, Swain PS. Stochastic gene expression in a single cell. Science (New York, N.Y.). 297: 1183-6. PMID 12183631 DOI: 10.1126/Science.1070919  0.244
2020 Hadjantonakis AK, Siggia ED, Simunovic M. In vitro modeling of early mammalian embryogenesis. Current Opinion in Biomedical Engineering. 13: 134-143. PMID 32440574 DOI: 10.1016/J.Cobme.2020.02.003  0.244
2007 Di Talia S, Skotheim JM, Bean JM, Siggia ED, Cross FR. The effects of molecular noise and size control on variability in the budding yeast cell cycle. Nature. 448: 947-51. PMID 17713537 DOI: 10.1038/Nature06072  0.243
2002 van Nimwegen E, Zavolan M, Rajewsky N, Siggia ED. Probabilistic clustering of sequences: inferring new bacterial regulons by comparative genomics. Proceedings of the National Academy of Sciences of the United States of America. 99: 7323-8. PMID 12032281 DOI: 10.1073/Pnas.112690399  0.241
2005 Cross FR, Siggia ED. Mode locking the cell cycle. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 72: 021910. PMID 16196607 DOI: 10.1103/Physreve.72.021910  0.241
2005 Mueller JL, Ravi Ram K, McGraw LA, Bloch Qazi MC, Siggia ED, Clark AG, Aquadro CF, Wolfner MF. Cross-species comparison of Drosophila male accessory gland protein genes. Genetics. 171: 131-43. PMID 15944345 DOI: 10.1534/Genetics.105.043844  0.24
2012 François P, Despierre N, Siggia ED. Adaptive temperature compensation in circadian oscillations. Plos Computational Biology. 8: e1002585. PMID 22807663 DOI: 10.1371/Journal.Pcbi.1002585  0.24
2013 Siggia ED, Vergassola M. Decisions on the fly in cellular sensory systems. Proceedings of the National Academy of Sciences of the United States of America. 110: E3704-12. PMID 24019464 DOI: 10.1073/Pnas.1314081110  0.238
2008 Tanay A, Siggia ED. Sequence context affects the rate of short insertions and deletions in flies and primates. Genome Biology. 9: R37. PMID 18291026 DOI: 10.1186/Gb-2008-9-2-R37  0.237
1993 Holzer M, Siggia E. Skewed, exponential pressure distributions from Gaussian velocities Physics of Fluids a: Fluid Dynamics. 5: 2525-2532. DOI: 10.1063/1.858765  0.237
2019 Martyn I, Brivanlou AH, Siggia ED. A wave of WNT signaling balanced by secreted inhibitors controls primitive streak formation in micropattern colonies of human embryonic stem cells. Development (Cambridge, England). 146. PMID 30814117 DOI: 10.1242/Dev.172791  0.236
2016 Deglincerti A, Etoc F, Guerra MC, Martyn I, Metzger J, Ruzo A, Simunovic M, Yoney A, Brivanlou AH, Siggia E, Warmflash A. Self-organization of human embryonic stem cells on micropatterns. Nature Protocols. 11: 2223-2232. PMID 27735934 DOI: 10.1038/Nprot.2016.131  0.236
1977 Siggia ED. Pseudospin formulation of kinetic Ising models Physical Review B. 16: 2319-2320. DOI: 10.1103/Physrevb.16.2319  0.235
1997 Chou T, Jarić MV, Siggia ED. Electrostatics of lipid bilayer bending. Biophysical Journal. 72: 2042-55. PMID 9129807 DOI: 10.1016/S0006-3495(97)78848-9  0.235
2008 Charvin G, Cross FR, Siggia ED. A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells. Plos One. 3: e1468. PMID 18213377 DOI: 10.1371/Journal.Pone.0001468  0.233
1985 Siggia E. Comment on dynamical theories of the liquid-glass transition. Physical Review A. 32: 3135-3138. PMID 9896469 DOI: 10.1103/Physreva.32.3135  0.232
2016 Keil W, Kutscher LM, Shaham S, Siggia ED. Long-Term High-Resolution Imaging of Developing C. elegans Larvae with Microfluidics. Developmental Cell. PMID 28041904 DOI: 10.1016/J.Devcel.2016.11.022  0.232
1989 Pumir A, Siggia E. Simulations of incipient singularities in the 3-D Euler equations Physica D: Nonlinear Phenomena. 37: 539-541. DOI: 10.1016/0167-2789(89)90158-9  0.232
1984 Siggia ED. The strong coupling limit of K.A.M. theory and the onset of turbulence Physics Reports. 103: 87-94. DOI: 10.1016/0370-1573(84)90068-1  0.232
1997 Sciaky N, Presley J, Smith C, Zaal KJ, Cole N, Moreira JE, Terasaki M, Siggia E, Lippincott-Schwartz J. Golgi tubule traffic and the effects of brefeldin A visualized in living cells. The Journal of Cell Biology. 139: 1137-55. PMID 9382862 DOI: 10.1083/Jcb.139.5.1137  0.231
2014 Warmflash A, Zhang Q, Brivanlou AH, Siggia ED. Comment on "Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway"-Smad2/3 activity does not predict the dynamics of transcription. Science Signaling. 7: lc1. PMID 25249655 DOI: 10.1126/Scisignal.2005562  0.23
1987 Siggia ED, Pumir A. A rapidly convergent method for the inversion of separable, positive, self-adjoint discrete elliptic operators in three or more dimensions Journal of Computational Physics. 72: 498-500. DOI: 10.1016/0021-9991(87)90096-9  0.23
2015 Kidd PB, Young MW, Siggia ED. Temperature compensation and temperature sensation in the circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 112: E6284-92. PMID 26578788 DOI: 10.1073/Pnas.1511215112  0.228
2018 Yoney A, Etoc F, Ruzo A, Carroll T, Metzger JJ, Martyn I, Li S, Kirst C, Siggia ED, Brivanlou AH. WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids. Elife. 7. PMID 30311909 DOI: 10.7554/Elife.38279  0.227
2016 Deglincerti A, Croft GF, Pietila LN, Zernicka-Goetz M, Siggia ED, Brivanlou AH. Self-organization of the in vitro attached human embryo. Nature. PMID 27144363 DOI: 10.1038/Nature17948  0.226
1981 Siggia ED, Zippelius A. Dynamics of defects in Rayleigh-Bénard convection Physical Review A. 24: 1036-1049. DOI: 10.1103/Physreva.24.1036  0.225
1997 Marko JF, Siggia ED. Polymer models of meiotic and mitotic chromosomes Molecular Biology of the Cell. 8: 2217-2231. PMID 9362064 DOI: 10.1091/Mbc.8.11.2217  0.224
2005 Cross FR, Siggia ED. Shake it, don't break it: positive feedback and the evolution of oscillator design. Developmental Cell. 9: 309-10. PMID 16139219 DOI: 10.1016/J.Devcel.2005.08.006  0.224
1976 Siggia ED. Critical dynamics of helium belowTc Physical Review B. 13: 3218-3221. DOI: 10.1103/Physrevb.13.3218  0.224
1977 Siggia ED. Critical dynamics of diluteHe3-He4mixtures Physical Review B. 15: 2830-2834. DOI: 10.1103/Physrevb.15.2830  0.223
1974 Halperin BI, Hohenberg PC, Siggia ED. Renormalization-group calculations of divergent transport coefficients at critical points Physical Review Letters. 32: 1289-1292. DOI: 10.1103/Physrevlett.32.1289  0.222
2011 Charvin G, Oikonomou C, Siggia ED, Cross FR. Correction: Origin of Irreversibility of Cell Cycle Start in Budding Yeast Plos Biology. 9. DOI: 10.1371/Annotation/90916531-1B34-4Eb5-92A9-A7F8C5D72318  0.22
1997 Ellenberg J, Siggia ED, Moreira JE, Smith CL, Presley JF, Worman HJ, Lippincott-Schwartz J. Nuclear membrane dynamics and reassembly in living cells: Targeting of an inner nuclear membrane protein in interphase and mitosis Journal of Cell Biology. 138: 1193-1206. PMID 9298976 DOI: 10.1083/Jcb.138.6.1193  0.22
1986 Ercolani N, Siggia ED. Painlevé property and integrability Physics Letters A. 119: 112-116. DOI: 10.1016/0375-9601(86)90426-3  0.22
1998 Hirschberg K, Miller CM, Ellenberg J, Presley JF, Siggia ED, Phair RD, Lippincott-Schwartz J. Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells. The Journal of Cell Biology. 143: 1485-503. PMID 9852146 DOI: 10.1083/Jcb.143.6.1485  0.219
2012 Warmflash A, Francois P, Siggia ED. Pareto evolution of gene networks: an algorithm to optimize multiple fitness objectives. Physical Biology. 9: 056001. PMID 22874123 DOI: 10.1088/1478-3975/9/5/056001  0.219
2019 Martyn I, Siggia ED, Brivanlou AH. Mapping cell migrations and fates in a gastruloid model to the human primitive streak. Development (Cambridge, England). 146. PMID 31427289 DOI: 10.1242/Dev.179564  0.217
1982 Zippelius A, Siggia ED. Disappearance of stable convection between free-slip boundaries Physical Review A. 26: 1788-1790. DOI: 10.1103/Physreva.26.1788  0.217
2002 Presley JF, Ward TH, Pfeifer AC, Siggia ED, Phair RD, Lippincott-Schwartz J. Dissection of COPI and Arf1 dynamics in vivo and role in Golgi membrane transport. Nature. 417: 187-93. PMID 12000962 DOI: 10.1038/417187A  0.216
2000 Nehls S, Snapp EL, Cole NB, Zaal KJM, Kenworthy AK, Roberts TH, Ellenberg J, Presley JF, Siggia E, Lippincott-Schwartz J. Dynamics and retention of misfolded proteins in native ER membranes Nature Cell Biology. 2: 288-295. PMID 10806480 DOI: 10.1038/35010558  0.216
1982 Rand D, Ostlund S, Sethna J, Siggia ED. Universal transition from quasiperiodicity to chaos in dissipative systems Physical Review Letters. 49: 132-135. DOI: 10.1103/Physrevlett.49.132  0.215
2007 Mwangi MM, Wu SW, Zhou Y, Sieradzki K, de Lencastre H, Richardson P, Bruce D, Rubin E, Myers E, Siggia ED, Tomasz A. Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing. Proceedings of the National Academy of Sciences of the United States of America. 104: 9451-6. PMID 17517606 DOI: 10.1073/Pnas.0609839104  0.212
1999 Zaal KJ, Smith CL, Polishchuk RS, Altan N, Cole NB, Ellenberg J, Hirschberg K, Presley JF, Roberts TH, Siggia E, Phair RD, Lippincott-Schwartz J. Golgi membranes are absorbed into and reemerge from the ER during mitosis. Cell. 99: 589-601. PMID 10612395 DOI: 10.1016/S0092-8674(00)81548-2  0.207
2002 Swain PS, Siggia ED. The role of proofreading in signal transduction specificity. Biophysical Journal. 82: 2928-33. PMID 12023215 DOI: 10.1016/S0006-3495(02)75633-6  0.206
1994 Bustamante C, Marko JF, Siggia ED, Smith S. Entropic elasticity of λ-phage DNA Science. 265: 1599-1600. PMID 8079175 DOI: 10.1126/Science.8079175  0.206
1995 Holzer M, Siggia E. Erratum: ‘‘Turbulent mixing of a passive scalar’’ [Phys. Fluids 6, 1820 (1994)] Physics of Fluids. 7: 1519-1519. DOI: 10.1063/1.868783  0.206
2018 Martyn I, Kanno TY, Ruzo A, Siggia ED, Brivanlou AH. Author Correction: Self-organization of a human organizer by combined Wnt and Nodal signalling. Nature. 564: E10. PMID 30420607 DOI: 10.1038/S41586-018-0583-3  0.202
2018 Yoney A, Etoc F, Ruzo A, Carroll T, Metzger JJ, Martyn I, Li S, Kirst C, Siggia ED, Brivanlou AH. Author response: WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids Elife. DOI: 10.7554/Elife.38279.033  0.193
1986 Frenkel DM, Henley CL, Siggia ED. Topological constraints on quasicrystal transformations. Physical Review. B, Condensed Matter. 34: 3649-3669. PMID 9940128 DOI: 10.1103/Physrevb.34.3649  0.183
1979 Siggia ED. Late stages of spinodal decomposition in binary mixtures Physical Review A. 20: 595-605. DOI: 10.1103/Physreva.20.595  0.18
2019 Campbell D, Gunaratne G, Siggia E. Mitchell Jay Feigenbaum Physics Today. 72: 67-67. DOI: 10.1063/Pt.3.4348  0.176
2021 Rand DA, Raju A, Sáez M, Corson F, Siggia ED. Geometry of gene regulatory dynamics. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34518231 DOI: 10.1073/pnas.2109729118  0.173
2016 Pumir A, Xu H, Siggia ED. Small-scale anisotropy in turbulent boundary layers Journal of Fluid Mechanics. 804: 5-23. DOI: 10.1017/Jfm.2016.529  0.167
1978 Siggia ED, Patterson GS. Intermittency effects in a numerical simulation of stationary three-dimensional turbulence Journal of Fluid Mechanics. 86: 567-592. DOI: 10.1017/S0022112078001287  0.163
2017 Corson F, Siggia ED. Gene-free methodology for cell fate dynamics during development. Elife. 6. PMID 29235987 DOI: 10.7554/eLife.30743  0.161
1978 Siggia ED. Model of intermittency in three-dimensional turbulence Physical Review A. 17: 1166-1176. DOI: 10.1103/PHYSREVA.17.1166  0.121
2021 Sáez M, Blassberg R, Camacho-Aguilar E, Siggia ED, Rand DA, Briscoe J. Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions. Cell Systems. PMID 34536382 DOI: 10.1016/j.cels.2021.08.013  0.117
1978 Ambegaokar V, Halperin BI, Nelson DR, Siggia ED. Dissipation in two-dimensional superfluids Physical Review Letters. 40: 783-786. DOI: 10.1103/Physrevlett.40.783  0.117
2008 Skotheim JM, Di Talia S, Siggia ED, Cross FR. Positive feedback of G1 cyclins ensures coherent cell cycle entry. Nature. 454: 291-6. PMID 18633409 DOI: 10.1038/nature07118  0.117
2019 Simunovic M, Metzger JJ, Etoc F, Yoney A, Ruzo A, Martyn I, Croft G, You DS, Brivanlou AH, Siggia ED. A 3D model of a human epiblast reveals BMP4-driven symmetry breaking. Nature Cell Biology. 21: 900-910. PMID 31263269 DOI: 10.1038/s41556-019-0349-7  0.115
2010 François P, Siggia ED. Predicting embryonic patterning using mutual entropy fitness and in silico evolution. Development (Cambridge, England). 137: 2385-95. PMID 20570938 DOI: 10.1242/dev.048033  0.114
2012 Corson F, Siggia ED. Geometry, epistasis, and developmental patterning. Proceedings of the National Academy of Sciences of the United States of America. 109: 5568-75. PMID 22434912 DOI: 10.1073/pnas.1201505109  0.113
2023 Raju A, Siggia ED. A geometrical perspective on development. Development, Growth & Differentiation. PMID 37190845 DOI: 10.1111/dgd.12855  0.113
1994 Marko JF, Siggia ED. Fluctuations and supercoiling of DNA Science. 265: 506-508. PMID 8036491 DOI: 10.1126/Science.8036491  0.106
2014 Warmflash A, Sorre B, Etoc F, Siggia ED, Brivanlou AH. A method to recapitulate early embryonic spatial patterning in human embryonic stem cells. Nature Methods. 11: 847-54. PMID 24973948 DOI: 10.1038/Nmeth.3016  0.101
2016 Etoc F, Metzger J, Ruzo A, Kirst C, Yoney A, Ozair MZ, Brivanlou AH, Siggia ED. A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization. Developmental Cell. PMID 27746044 DOI: 10.1016/J.Devcel.2016.09.016  0.099
2019 Shahbazi MN, Siggia ED, Zernicka-Goetz M. Self-organization of stem cells into embryos: A window on early mammalian development. Science (New York, N.Y.). 364: 948-951. PMID 31171690 DOI: 10.1126/science.aax0164  0.093
2022 Simunovic M, Siggia ED, Brivanlou AH. In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells. Cell Stem Cell. 29: 962-972.e4. PMID 35659878 DOI: 10.1016/j.stem.2022.05.001  0.093
2021 Valet M, Siggia ED, Brivanlou AH. Mechanical regulation of early vertebrate embryogenesis. Nature Reviews. Molecular Cell Biology. PMID 34754086 DOI: 10.1038/s41580-021-00424-z  0.091
2021 Phan-Everson T, Etoc F, Li S, Khodursky S, Yoney A, Brivanlou AH, Siggia ED. Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport. Developmental Cell. PMID 34051144 DOI: 10.1016/j.devcel.2021.05.003  0.088
2022 Yoney A, Bai L, Brivanlou AH, Siggia ED. Mechanisms underlying WNT-mediated priming of human embryonic stem cells. Development (Cambridge, England). 149. PMID 35815787 DOI: 10.1242/dev.200335  0.087
2018 Morgani SM, Metzger JJ, Nichols J, Siggia ED, Hadjantonakis AK. Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. Elife. 7. PMID 29412136 DOI: 10.7554/Elife.32839  0.085
2018 Siggia ED, Warmflash A. Modeling Mammalian Gastrulation With Embryonic Stem Cells. Current Topics in Developmental Biology. 129: 1-23. PMID 29801527 DOI: 10.1016/Bs.Ctdb.2018.03.001  0.084
2017 Siggia ED. A Geometric Model of Stripe Refinement. Developmental Cell. 41: 225-227. PMID 28486128 DOI: 10.1016/j.devcel.2017.04.016  0.084
2012 Warmflash A, Zhang Q, Sorre B, Vonica A, Siggia ED, Brivanlou AH. Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4. Proceedings of the National Academy of Sciences of the United States of America. 109: E1947-56. PMID 22689943 DOI: 10.1073/Pnas.1207607109  0.081
1991 CLAVIN P, SIGGIA ED. Turbulent Premixed Flames and Sound Generation Combustion Science and Technology. 78: 147-155. DOI: 10.1080/00102209108951745  0.076
1997 Marko JF, Siggia ED. Driving proteins off DNA using applied tension Biophysical Journal. 73: 2173-2178. PMID 9336213 DOI: 10.1016/S0006-3495(97)78248-1  0.073
2014 Sorre B, Warmflash A, Brivanlou AH, Siggia ED. Encoding of temporal signals by the TGF-β pathway and implications for embryonic patterning. Developmental Cell. 30: 334-42. PMID 25065773 DOI: 10.1016/J.Devcel.2014.05.022  0.068
2007 Di Talia S, Skotheim JM, Bean JM, Siggia ED, Cross FR. The effects of molecular noise and size control on variability in the budding yeast cell cycle (Nature (2007) 448, (947-951)) Nature. 450: 1272. DOI: 10.1038/nature06511  0.055
1972 Schwartz L, Siggia E. Pair Effects in Substitutional Alloys. I. Systematic Analysis of the Coherent-Potential Approximation Physical Review B. 5: 383-396. DOI: 10.1103/PHYSREVB.5.383  0.053
1995 Thompson RE, Siggia ED. Physical limits on the mechanical measurement of the secondary structure of bio-molecules Epl. 31: 335-340. DOI: 10.1209/0295-5075/31/5-6/015  0.052
1970 Siggia ED, Kwok PC. Properties of Electrons in Semiconductor Inversion Layers with Many Occupied Electric Subbands. I. Screening and Impurity Scattering Physical Review B. 2: 1024-1036. DOI: 10.1103/PHYSREVB.2.1024  0.047
2022 Metzger JJ, Pereda C, Adhikari A, Haremaki T, Galgoczi S, Siggia ED, Brivanlou AH, Etoc F. Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models. Cell Reports Methods. 2: 100297. PMID 36160045 DOI: 10.1016/j.crmeth.2022.100297  0.045
1974 Siggia ED. k→·p→perturbation theory in semiconductor alloys Physical Review B. 10: 5147-5158. DOI: 10.1103/PHYSREVB.10.5147  0.042
2012 Siggia ED. Profile of Eric D. Siggia. Interview by Farooq Ahmed. Proceedings of the National Academy of Sciences of the United States of America. 109: 5551-2. PMID 22474368 DOI: 10.1073/pnas.1204149109  0.041
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