| Year |
Citation |
Score |
| 2023 |
Canals I, Comella-Bolla A, Cepeda-Prado E, Avaliani N, Crowe JA, Oburoglu L, Bruzelius A, King N, Pajares MA, Pérez-Sala D, Heuer A, Rylander Ottosson D, Soriano J, Ahlenius H. Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia. Brain Communications. 5: fcad158. PMID 37274831 DOI: 10.1093/braincomms/fcad158 |
0.404 |
|
| 2022 |
Trovato F, Stefani FR, Li J, Zetterdahl OG, Canals I, Ahlenius H, Bengzon J. Transcription Factor Forced Astrocytic Differentiation Impairs Human Glioblastoma Growth In Vitro and In Vivo. Molecular Cancer Therapeutics. PMID 36508391 DOI: 10.1158/1535-7163.MCT-21-0903 |
0.333 |
|
| 2022 |
Quist E, Trovato F, Avaliani N, Zetterdahl OG, Gonzalez-Ramos A, Hansen MG, Kokaia M, Canals I, Ahlenius H. Transcription factor-based direct conversion of human fibroblasts to functional astrocytes. Stem Cell Reports. PMID 35750047 DOI: 10.1016/j.stemcr.2022.05.015 |
0.337 |
|
| 2021 |
Canals I, Quist E, Ahlenius H. Transcription Factor-Based Strategies to Generate Neural Cell Types from Human Pluripotent Stem Cells. Cellular Reprogramming. 23: 206-220. PMID 34388027 DOI: 10.1089/cell.2021.0045 |
0.417 |
|
| 2021 |
Canals I, Ahlenius H. CRISPR/Cas9 Genome Engineering in Human Pluripotent Stem Cells for Modeling of Neurological Disorders. Methods in Molecular Biology (Clifton, N.J.). 2352: 237-251. PMID 34324191 DOI: 10.1007/978-1-0716-1601-7_16 |
0.47 |
|
| 2021 |
Quist E, Ahlenius H, Canals I. Transcription Factor Programming of Human Pluripotent Stem Cells to Functionally Mature Astrocytes for Monocultures and Cocultures with Neurons. Methods in Molecular Biology (Clifton, N.J.). 2352: 133-148. PMID 34324185 DOI: 10.1007/978-1-0716-1601-7_10 |
0.347 |
|
| 2021 |
Benetó N, Grinberg D, Vilageliu L, Canals I. Genome Editing Using Cas9-gRNA Ribonucleoprotein in Human Pluripotent Stem Cells for Disease Modeling. Methods in Molecular Biology (Clifton, N.J.). PMID 33755903 DOI: 10.1007/7651_2021_374 |
0.744 |
|
| 2021 |
Tolomeo AM, Laterza C, Grespan E, Michielin F, Canals I, Kokaia Z, Muraca M, Gagliano O, Elvassore N. mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities. Frontiers in Cellular Neuroscience. 15: 602888. PMID 33679325 DOI: 10.3389/fncel.2021.602888 |
0.315 |
|
| 2020 |
Benetó N, Vilageliu L, Grinberg D, Canals I. Sanfilippo Syndrome: Molecular Basis, Disease Models and Therapeutic Approaches. International Journal of Molecular Sciences. 21. PMID 33105639 DOI: 10.3390/ijms21217819 |
0.759 |
|
| 2020 |
Galera-Monge T, Zurita-Díaz F, Canals I, Hansen MG, Rufián-Vázquez L, Ehinger JK, Elmér E, Martin MA, Garesse R, Ahlenius H, Gallardo ME. Mitochondrial Dysfunction and Calcium Dysregulation in Leigh Syndrome Induced Pluripotent Stem Cell Derived Neurons. International Journal of Molecular Sciences. 21. PMID 32366037 DOI: 10.3390/ijms21093191 |
0.423 |
|
| 2020 |
Benetó N, Cozar M, Castilla-Vallmanya L, Zetterdahl OG, Sacultanu M, Segur-Bailach E, García-Morant M, Ribes A, Ahlenius H, Grinberg D, Vilageliu L, Canals I. Neuronal and Astrocytic Differentiation from Sanfilippo C Syndrome iPSCs for Disease Modeling and Drug Development. Journal of Clinical Medicine. 9. PMID 32121121 DOI: 10.3390/Jcm9030644 |
0.692 |
|
| 2019 |
Benetó N, Cozar M, Gort L, Pacheco L, Vilageliu L, Grinberg D, Canals I. Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome. Stem Cell Research. 42: 101668. PMID 31825816 DOI: 10.1016/J.Scr.2019.101668 |
0.752 |
|
| 2019 |
Benetó N, Cozar M, García-Morant M, Creus-Bachiller E, Vilageliu L, Grinberg D, Canals I. Generation of two compound heterozygous HGSNAT-mutated lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo C syndrome. Stem Cell Research. 41: 101616. PMID 31731183 DOI: 10.1016/J.Scr.2019.101616 |
0.758 |
|
| 2019 |
Hansen MG, Tornero D, Canals I, Ahlenius H, Kokaia Z. In Vitro Functional Characterization of Human Neurons and Astrocytes Using Calcium Imaging and Electrophysiology. Methods in Molecular Biology (Clifton, N.J.). 1919: 73-88. PMID 30656622 DOI: 10.1007/978-1-4939-9007-8_6 |
0.388 |
|
| 2018 |
Canals I, Ginisty A, Quist E, Timmerman R, Fritze J, Miskinyte G, Monni E, Hansen MG, Hidalgo I, Bryder D, Bengzon J, Ahlenius H. Rapid and efficient induction of functional astrocytes from human pluripotent stem cells. Nature Methods. 15: 693-696. PMID 30127505 DOI: 10.1038/S41592-018-0103-2 |
0.365 |
|
| 2015 |
Canals I, Soriano J, Orlandi JG, Torrent R, Richaud-Patin Y, Jiménez-Delgado S, Merlin S, Follenzi A, Consiglio A, Vilageliu L, Grinberg D, Raya A. Activity and High-Order Effective Connectivity Alterations in Sanfilippo C Patient-Specific Neuronal Networks. Stem Cell Reports. 5: 546-57. PMID 26411903 DOI: 10.1016/J.Stemcr.2015.08.016 |
0.762 |
|
| 2015 |
Canals I, Benetó N, Cozar M, Vilageliu L, Grinberg D. EXTL2 and EXTL3 inhibition with siRNAs as a promising substrate reduction therapy for Sanfilippo C syndrome. Scientific Reports. 5: 13654. PMID 26347037 DOI: 10.1038/Srep13654 |
0.714 |
|
| 2014 |
Matos L, Canals I, Dridi L, Choi Y, Prata MJ, Jordan P, Desviat LR, Pérez B, Pshezhetsky AV, Grinberg D, Alves S, Vilageliu L. Therapeutic strategies based on modified U1 snRNAs and chaperones for Sanfilippo C splicing mutations. Orphanet Journal of Rare Diseases. 9: 180. PMID 25491247 DOI: 10.1186/S13023-014-0180-Y |
0.731 |
|
| 2011 |
Canals I, Elalaoui SC, Pineda M, Delgadillo V, Szlago M, Jaouad IC, Sefiani A, Chabás A, Coll MJ, Grinberg D, Vilageliu L. Molecular analysis of Sanfilippo syndrome type C in Spain: seven novel HGSNAT mutations and characterization of the mutant alleles. Clinical Genetics. 80: 367-74. PMID 20825431 DOI: 10.1111/J.1399-0004.2010.01525.X |
0.722 |
|
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