| Year |
Citation |
Score |
| 2024 |
Guo SC, Shen R, Roux B, Dinner AR. Dynamics of activation in the voltage-sensing domain of Ciona intestinalis phosphatase Ci-VSP. Nature Communications. 15: 1408. PMID 38360718 DOI: 10.1038/s41467-024-45514-6 |
0.465 |
|
| 2023 |
Shen R, Roux B, Perozo E. Anionic omega currents from single countercharge mutants in the voltage-sensing domain of Ci-VSP. The Journal of General Physiology. 156. PMID 38019193 DOI: 10.1085/jgp.202213311 |
0.611 |
|
| 2022 |
Shen R, Meng Y, Roux B, Perozo E. Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206649119. PMID 36279472 DOI: 10.1073/pnas.2206649119 |
0.64 |
|
| 2022 |
Zhao R, Shen R, Dai H, Perozo E, Goldstein SAN. Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120750119. PMID 35648818 DOI: 10.1073/pnas.2120750119 |
0.597 |
|
| 2021 |
Bavi N, Clark MD, Contreras GF, Shen R, Reddy BG, Milewski W, Perozo E. Prestin's conformational cycle underlies outer hair cell electromotility. Nature. PMID 34695838 DOI: 10.1038/s41586-021-04152-4 |
0.675 |
|
| 2021 |
Li J, Shen R, Rohaim A, Mendoza Uriarte R, Fajer M, Perozo E, Roux B. Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel. The Journal of General Physiology. 153. PMID 34357375 DOI: 10.1085/jgp.202112875 |
0.664 |
|
| 2021 |
Zhao R, Dai H, Arias RJ, De Blas GA, Orta G, Pavarotti MA, Shen R, Perozo E, Mayorga LS, Darszon A, Goldstein SAN. Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils. Nature Communications. 12: 3855. PMID 34158477 DOI: 10.1038/s41467-021-24145-1 |
0.614 |
|
| 2021 |
Li J, Shen R, Reddy B, Perozo E, Roux B. Mechanism of C-type inactivation in the hERG potassium channel. Science Advances. 7. PMID 33514547 DOI: 10.1126/sciadv.abd6203 |
0.749 |
|
| 2021 |
Li J, Shen R, Perozo E, Roux B. An Asymmetric C-Type Inactivated Structure of HERG Channel and Its Binding to Chemically Diverse Drugs Biophysical Journal. 120: 245a. DOI: 10.1016/J.BPJ.2020.11.1604 |
0.332 |
|
| 2020 |
Clark MD, Contreras GF, Shen R, Perozo E. Electromechanical coupling in the hyperpolarization-activated K channel KAT1. Nature. PMID 32461693 DOI: 10.1038/S41586-020-2335-4 |
0.783 |
|
| 2020 |
Li J, Shen R, Hoon Koh Y, Perozo E, Roux B. Molecular Determinants of C-type Inactivation for the hERG Channel and Its Disease-associated Mutants Biophysical Journal. 118: 111a. DOI: 10.1016/J.Bpj.2019.11.755 |
0.618 |
|
| 2020 |
Shen R, Roux B, Perozo E. The Energy Landscape of Voltage Sensing in Ci-VSP Biophysical Journal. 118: 269a. DOI: 10.1016/J.Bpj.2019.11.1550 |
0.562 |
|
| 2020 |
Contreras GF, Clark MD, Shen R, Perozo E. A Molecular Mechanism for Gating Polarity in Non-Domain-Swapped Kv Channels Biophysical Journal. 118: 260a-261a. DOI: 10.1016/J.Bpj.2019.11.1511 |
0.75 |
|
| 2019 |
Clark MD, Contreras G, Shen R, Perozo E. Structural Basis for Electromechanical Coupling in a Hyperpolarization-Activated Ion Channel Biophysical Journal. 116: 15a. DOI: 10.1016/J.Bpj.2018.11.123 |
0.746 |
|
| 2017 |
Dang B, Shen R, Kubota T, Mandal K, Bezanilla F, Roux B, Kent SB. Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angewandte Chemie (International Ed. in English). PMID 28194851 DOI: 10.1002/Anie.201612398 |
0.557 |
|
| 2016 |
Shen R, Li Q, Medovoy D, Meng Y, Roux B, Perozo E. Computational Characterization of Conformational Transitions in the Voltage-Sensing Domain of Ci-VSP Biophysical Journal. 110: 106a. DOI: 10.1016/J.Bpj.2015.11.629 |
0.744 |
|
| 2016 |
Islam SM, Florin G, Qi Y, Shen R, Han W, Stein RA, Schulten K, Mchaourab HS, Im W, Roux B. Structural-Function Study of Membrane Proteins with Restrained-Ensemble and Dummy Spin-Label Molecular Dynamics Simulations Biophysical Journal. 110: 644a. DOI: 10.1016/J.Bpj.2015.11.3446 |
0.334 |
|
| 2015 |
Shen R, Han W, Fiorin G, Islam SM, Schulten K, Roux B. Structural Refinement of Proteins by Restrained Molecular Dynamics Simulations with Non-interacting Molecular Fragments. Plos Computational Biology. 11: e1004368. PMID 26505197 DOI: 10.1371/Journal.Pcbi.1004368 |
0.409 |
|
| 2015 |
Li Q, Shen R, Treger JS, Wanderling SS, Milewski W, Siwowska K, Bezanilla F, Perozo E. Resting state of the human proton channel dimer in a lipid bilayer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26443860 DOI: 10.1073/Pnas.1515043112 |
0.754 |
|
| 2012 |
Qiu H, Shen R, Guo W. Ion solvation and structural stability in a sodium channel investigated by molecular dynamics calculations. Biochimica Et Biophysica Acta. 1818: 2529-35. PMID 22699041 DOI: 10.1016/j.bbamem.2012.06.003 |
0.368 |
|
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