Christopher Tate - Publications

Affiliations: 
Oak Ridge National Laboratory, Oak Ridge, TN, United States 

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wu N, Olechwier AM, Brunner C, Edwards PC, Tsai CJ, Tate CG, Schertler GFX, Schneider G, Deupi X, Zenobi R, Ma P. High-mass MALDI-MS unravels ligand-mediated G protein-coupling selectivity to GPCRs. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34326250 DOI: 10.1073/pnas.2024146118  1
2020 Vijayan SM, Sparks N, Roy JK, Smith C, Tate C, Hammer NI, Leszczynski J, Watkins DL. Evaluating Donor Effects in Isoindigo-Based Small Molecular Fluorophores. The Journal of Physical Chemistry. A. PMID 33305579 DOI: 10.1021/acs.jpca.0c07796  0.01
2020 Velazhahan V, Ma N, Pándy-Szekeres G, Kooistra AJ, Lee Y, Gloriam DE, Vaidehi N, Tate CG. Structure of the class D GPCR Ste2 dimer coupled to two G proteins. Nature. PMID 33268889 DOI: 10.1038/s41586-020-2994-1  1
2020 Hunter RF, Montes F, Murray JM, Sanchez-Franco SC, Montgomery SC, Jaramillo J, Tate C, Kumar R, Dunne L, Ramalingam A, Kimbrough EO, Krupka E, Zhou H, Moore L, Bauld L, et al. MECHANISMS Study: Using Game Theory to Assess the Effects of Social Norms and Social Networks on Adolescent Smoking in Schools-Study Protocol. Frontiers in Public Health. 8: 377. PMID 32850598 DOI: 10.3389/Fpubh.2020.00377  0.01
2020 Lee Y, Warne T, Nehmé R, Pandey S, Dwivedi-Agnihotri H, Chaturvedi M, Edwards PC, García-Nafría J, Leslie AGW, Shukla AK, Tate CG. Molecular basis of β-arrestin coupling to formoterol-bound β-adrenoceptor. Nature. PMID 32555462 DOI: 10.1038/S41586-020-2419-1  1
2020 Lee S, Ghosh S, Jana S, Robertson N, Tate CG, Vaidehi N. How do branched detergents stabilize GPCRs in micelles? Biochemistry. PMID 32437610 DOI: 10.1021/Acs.Biochem.0C00183  1
2020 Congreve M, de Graaf C, Swain NA, Tate CG. Impact of GPCR Structures on Drug Discovery. Cell. 181: 81-91. PMID 32243800 DOI: 10.1016/j.cell.2020.03.003  1
2020 Pamula F, Mühle J, Blanc A, Nehmé R, Edwards PC, Tate CG, Tsai CJ. Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization. Journal of Visualized Experiments : Jove. PMID 32225143 DOI: 10.3791/60747  1
2019 Dal Maso E, Glukhova A, Zhu Y, Garcia-Nafria J, Tate CG, Atanasio S, Reynolds CA, Ramírez-Aportela E, Carazo JM, Hick CA, Furness SGB, Hay DL, Liang YL, Miller LJ, Christopoulos A, et al. The Molecular Control of Calcitonin Receptor Signaling. Acs Pharmacology & Translational Science. 2: 31-51. PMID 32219215 DOI: 10.1021/acsptsci.8b00056  0.01
2019 Muk S, Ghosh S, Achuthan S, Chen X, Yao X, Sandhu M, Griffor MC, Fennell KF, Che Y, Shanmugasundaram V, Qiu X, Tate CG, Vaidehi N. Machine Learning for Prioritization of Thermostabilizing Mutations for G-Protein Coupled Receptors. Biophysical Journal. PMID 31703801 DOI: 10.1016/J.Bpj.2019.10.023  1
2019 García-Nafría J, Tate CG. Cryo-Electron Microscopy: Moving Beyond X-Ray Crystal Structures for Drug Receptors and Drug Development. Annual Review of Pharmacology and Toxicology. PMID 31348870 DOI: 10.1146/annurev-pharmtox-010919-023545  1
2019 Wu C, Wynne SA, Thomas NE, Uhlemann EM, Tate CG, Henzler-Wildman KA. Identification of an Alternating-Access Dynamics Mutant of EmrE with Impaired Transport. Journal of Molecular Biology. PMID 31158365 DOI: 10.1016/j.jmb.2019.05.035  0.01
2019 Warne T, Edwards PC, Doré AS, Leslie AGW, Tate CG. Molecular basis for high-affinity agonist binding in GPCRs. Science (New York, N.Y.). PMID 31072904 DOI: 10.1126/science.aau5595  1
2019 García-Nafría J, Tate CG. Cryo-EM structures of GPCRs coupled to G, G and G. Molecular and Cellular Endocrinology. PMID 30930094 DOI: 10.1016/j.mce.2019.02.006  1
2019 Lee S, Nivedha AK, Tate CG, Vaidehi N. Dynamic Role of the G Protein in Stabilizing the Active State of the Adenosine A Receptor. Structure (London, England : 1993). PMID 30713025 DOI: 10.1016/j.str.2018.12.007  1
2018 Tsai CJ, Pamula F, Nehmé R, Mühle J, Weinert T, Flock T, Nogly P, Edwards PC, Carpenter B, Gruhl T, Ma P, Deupi X, Standfuss J, Tate CG, Schertler GFX. Crystal structure of rhodopsin in complex with a mini-G sheds light on the principles of G protein selectivity. Science Advances. 4: eaat7052. PMID 30255144 DOI: 10.1126/Sciadv.Aat7052  1
2018 Yen HY, Hoi KK, Liko I, Hedger G, Horrell MR, Song W, Wu D, Heine P, Warne T, Lee Y, Carpenter B, Plückthun A, Tate CG, Sansom MSP, Robinson CV. PtdIns(4,5)P stabilizes active states of GPCRs and enhances selectivity of G-protein coupling. Nature. PMID 29995853 DOI: 10.1038/S41586-018-0325-6  1
2018 García-Nafría J, Nehmé R, Edwards PC, Tate CG. Cryo-EM structure of the serotonin 5-HT receptor coupled to heterotrimeric G. Nature. PMID 29925951 DOI: 10.1038/s41586-018-0241-9  1
2018 García-Nafría J, Lee Y, Bai X, Carpenter B, Tate CG. Cryo-EM structure of the adenosine A receptor coupled to an engineered heterotrimeric G protein. Elife. 7. PMID 29726815 DOI: 10.7554/Elife.35946  1
2018 Wan Q, Okashah N, Inoue A, Nehmé R, Carpenter B, Tate CG, Lambert NA. Mini G protein probes for active G protein-coupled receptors (GPCRs) in live cells. The Journal of Biological Chemistry. PMID 29523687 DOI: 10.1074/jbc.RA118.001975  1
2018 García-Nafría J, Lee Y, Bai X, Carpenter B, Tate CG. Author response: Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein Elife. DOI: 10.7554/Elife.35946.020  1
2017 Solt AS, Bostock MJ, Shrestha B, Kumar P, Warne T, Tate CG, Nietlispach D. Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor. Nature Communications. 8: 1795. PMID 29176642 DOI: 10.1038/s41467-017-02008-y  1
2017 Strege A, Carpenter B, Edwards PC, Tate CG. Strategy for the Thermostabilization of an Agonist-Bound GPCR Coupled to a G Protein. Methods in Enzymology. 594: 243-264. PMID 28779842 DOI: 10.1016/bs.mie.2017.05.014  1
2017 Carpenter B, Tate CG. Expression, Purification and Crystallisation of the Adenosine A2A Receptor Bound to an Engineered Mini G Protein. Bio-Protocol. 7. PMID 28660236 DOI: 10.21769/BioProtoc.2234  1
2017 Carpenter B, Tate CG. Active state structures of G protein-coupled receptors highlight the similarities and differences in the G protein and arrestin coupling interfaces. Current Opinion in Structural Biology. 45: 124-132. PMID 28482214 DOI: 10.1016/j.sbi.2017.04.010  1
2017 Carpenter B, Tate CG. Expression and Purification of Mini G Proteins from Escherichia coli. Bio-Protocol. 7. PMID 28480316 DOI: 10.21769/BioProtoc.2235  1
2017 Nehmé R, Carpenter B, Singhal A, Strege A, Edwards PC, White CF, Du H, Grisshammer R, Tate CG. Mini-G proteins: Novel tools for studying GPCRs in their active conformation. Plos One. 12: e0175642. PMID 28426733 DOI: 10.1371/journal.pone.0175642  1
2017 Tate CG. Structural biology: A receptor that might block itself. Nature. PMID 28379949 DOI: 10.1038/nature21907  0.01
2016 Lee S, Mao A, Bhattacharya S, Robertson N, Grisshammer R, Tate CG, Vaidehi N. How do short chain non-ionic detergents destabilize GPCRs? Journal of the American Chemical Society. PMID 27792324 DOI: 10.1021/Jacs.6B08742  1
2016 Carpenter B, Tate CG. Engineering a minimal G protein to facilitate crystallisation of G protein-coupled receptors in their active conformation. Protein Engineering, Design & Selection : Peds. PMID 27672048 DOI: 10.1093/protein/gzw049  1
2016 Carpenter B, Nehmé R, Warne T, Leslie AG, Tate CG. Erratum: Structure of the adenosine A2A receptor bound to an engineered G protein. Nature. PMID 27629518 DOI: 10.1038/nature19803  1
2016 Venkatakrishnan AJ, Deupi X, Lebon G, Heydenreich FM, Flock T, Miljus T, Balaji S, Bouvier M, Veprintsev DB, Tate CG, Schertler GF, Babu MM. Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region. Nature. PMID 27525504 DOI: 10.1038/Nature19107  1
2016 Andréll J, Edwards PC, Zhang F, Daly M, Tate CG. Generation of Tetracycline-Inducible Mammalian Cell Lines by Flow Cytometry for Improved Overproduction of Membrane Proteins. Methods in Molecular Biology (Clifton, N.J.). 1432: 63-78. PMID 27485330 DOI: 10.1007/978-1-4939-3637-3_5  1
2016 Magnani F, Serrano-Vega MJ, Shibata Y, Abdul-Hussein S, Lebon G, Miller-Gallacher J, Singhal A, Strege A, Thomas JA, Tate CG. A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies. Nature Protocols. 11: 1554-1571. PMID 27466713 DOI: 10.1038/Nprot.2016.088  1
2016 Carpenter B, Nehmé R, Warne T, Leslie AG, Tate CG. Structure of the adenosine A2A receptor bound to an engineered G protein. Nature. PMID 27462812 DOI: 10.1038/nature18966  1
2016 Priola JJ, Calzadilla N, Baumann M, Borth N, Tate CG, Betenbaugh MJ. High-throughput screening and selection of mammalian cells for enhanced protein production. Biotechnology Journal. PMID 27276699 DOI: 10.1002/Biot.201500579  1
2016 Di Bartolo N, Compton EL, Warne T, Edwards PC, Tate CG, Schertler GF, Booth PJ. Complete Reversible Refolding of a G-Protein Coupled Receptor on a Solid Support. Plos One. 11: e0151582. PMID 26982879 DOI: 10.1371/journal.pone.0151582  1
2016 Vaidehi N, Lee S, Bhattacharya S, Sandhu M, Grisshammer R, Tate CG. Insights into How Mutations Thermostabilize G-Protein-Coupled Receptors Biophysical Journal. 110: 39. DOI: 10.1016/J.Bpj.2015.11.281  1
2016 Lee S, Bhattacharya S, Mao A, Grisshammer R, Tate C, Vaidehi N. Insights into the Stability of GPCRs in Detergent Micelles Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1265  1
2015 Leslie AG, Warne T, Tate CG. Ligand occupancy in crystal structure of β1-adrenergic G protein-coupled receptor. Nature Structural & Molecular Biology. 22: 941-2. PMID 26643842 DOI: 10.1038/nsmb.3130  1
2015 Vaidehi N, Grisshammer R, Tate CG. How Can Mutations Thermostabilize G-Protein-Coupled Receptors? Trends in Pharmacological Sciences. PMID 26547284 DOI: 10.1016/j.tips.2015.09.005  1
2015 Tate CG. Identifying Thermostabilizing Mutations in Membrane Proteins by Bioinformatics. Biophysical Journal. 109: 1307-8. PMID 26445428 DOI: 10.1016/j.bpj.2015.08.020  1
2015 Sato T, Baker J, Warne T, Brown G, Leslie A, Congreve M, Tate C. Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound β1-Adrenergic Receptor. Molecular Pharmacology. PMID 26385885 DOI: 10.1124/mol.115.101030  1
2015 Tate CG, Lebon G. Purification and Crystallization of a Thermostabilized Agonist-Bound Conformation of the Human Adenosine A2A Receptor. Methods in Molecular Biology (Clifton, N.J.). 1335: 17-27. PMID 26260591 DOI: 10.1007/978-1-4939-2914-6_2  1
2015 Flock T, Ravarani CN, Sun D, Venkatakrishnan AJ, Kayikci M, Tate CG, Veprintsev DB, Babu MM. Universal allosteric mechanism for Gα activation by GPCRs. Nature. 524: 173-9. PMID 26147082 DOI: 10.1038/nature14663  1
2015 Wright DJ, Tate CG. Isolation and characterisation of transport-defective substrate-binding mutants of the tetracycline antiporter TetA(B). Biochimica Et Biophysica Acta. 1848: 2261-2270. PMID 26143388 DOI: 10.1016/j.bbamem.2015.06.026  0.01
2015 Braunschweig H, Dewhurst RD, Hupp F, Nutz M, Radacki K, Tate CW, Vargas A, Ye Q. Multiple complexation of CO and related ligands to a main-group element. Nature. 522: 327-30. PMID 26085273 DOI: 10.1038/Nature14489  1
2015 Weyand S, Tate CG. Advances in membrane protein crystallography: in situ and in meso data collection. Acta Crystallographica. Section D, Biological Crystallography. 71: 1226-7. PMID 26057663 DOI: 10.1107/S1399004715008317  1
2015 Lee S, Bhattacharya S, Tate CG, Grisshammer R, Vaidehi N. Structural dynamics and thermostabilization of neurotensin receptor 1. The Journal of Physical Chemistry. B. 119: 4917-28. PMID 25807267 DOI: 10.1021/Jp510735F  1
2015 Heifetz A, Schertler GF, Seifert R, Tate CG, Sexton PM, Gurevich VV, Fourmy D, Cherezov V, Marshall FH, Storer RI, Moraes I, Tikhonova IG, Tautermann CS, Hunt P, Ceska T, et al. GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. Naunyn-Schmiedeberg's Archives of Pharmacology. 388: 883-903. PMID 25772061 DOI: 10.1007/S00210-015-1111-8  1
2015 Lebon G, Edwards PC, Leslie AG, Tate CG. Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor. Molecular Pharmacology. 87: 907-15. PMID 25762024 DOI: 10.1124/mol.114.097360  1
2015 Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T, Wang Y, ... Tate C, et al. Real-time resolution of point mutations that cause phenovariance in mice. Proceedings of the National Academy of Sciences of the United States of America. 112: E440-9. PMID 25605905 DOI: 10.1073/Pnas.1423216112  1
2015 McNamara AA, Johnson LE, Tate C, Chiang T, Byrne T. Acquisition of operant behavior in rats with delayed reinforcement: A retractable-lever procedure. Behavioural Processes. 111: 37-41. PMID 25464338 DOI: 10.1016/j.beproc.2014.11.014  1
2015 Wright DJ, Tate CG. Isolation and characterisation of transport-defective substrate-binding mutants of the tetracycline antiporter TetA(B) Biochimica Et Biophysica Acta - Biomembranes. 1848: 2261-2270. DOI: 10.1016/j.bbamem.2015.06.026  1
2014 Thomas J, Tate CG. Quality control in eukaryotic membrane protein overproduction. Journal of Molecular Biology. 426: 4139-54. PMID 25454020 DOI: 10.1016/j.jmb.2014.10.012  1
2014 Bhattacharya S, Lee S, Grisshammer R, Tate CG, Vaidehi N. Rapid Computational Prediction of Thermostabilizing Mutations for G Protein-Coupled Receptors. Journal of Chemical Theory and Computation. 10: 5149-5160. PMID 25400524 DOI: 10.1021/Ct500616V  1
2014 Takagi J, Tate CG. Editorial overview: New constructs and expression of proteins: Making things better. Current Opinion in Structural Biology. 26: iv-vi. PMID 24948361 DOI: 10.1016/j.sbi.2014.05.001  1
2014 Braunschweig H, Dewhurst RD, Radacki K, Tate CW, Vargas A. Trihapto ligation of a borirene to a single metal atom: a heterocyclic analogue of the η³-cyclopropenyl ligand. Angewandte Chemie (International Ed. in English). 53: 6263-6. PMID 24802284 DOI: 10.1002/Anie.201402815  1
2014 Miller-Gallacher JL, Nehmé R, Warne T, Edwards PC, Schertler GF, Leslie AG, Tate CG. The 2.1 Ã… resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor. Plos One. 9: e92727. PMID 24663151 DOI: 10.1371/journal.pone.0092727  1
2014 Lee S, Bhattacharya S, Grisshammer R, Tate C, Vaidehi N. Dynamic behavior of the active and inactive states of the adenosine A(2A) receptor. The Journal of Physical Chemistry. B. 118: 3355-65. PMID 24579769 DOI: 10.1021/Jp411618H  1
2013 Campbell NG, Zhu CB, Lindler KM, Yaspan BL, Kistner-Griffin E, Hewlett WA, Tate CG, Blakely RD, Sutcliffe JS. Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome. Molecular Autism. 4: 28. PMID 23953133 DOI: 10.1186/2040-2392-4-28  1
2013 Braunschweig H, Dewhurst RD, Hörl C, Radacki K, Tate CW, Vargas A, Ye Q. Reductive borylene-CO coupling with a bulky arylborylene complex. Angewandte Chemie (International Ed. in English). 52: 10120-3. PMID 23894013 DOI: 10.1002/Anie.201303798  1
2013 Abdul-Hussein S, Andréll J, Tate CG. Thermostabilisation of the serotonin transporter in a cocaine-bound conformation. Journal of Molecular Biology. 425: 2198-207. PMID 23706649 DOI: 10.1016/j.jmb.2013.03.025  1
2013 Niesen MJ, Bhattacharya S, Grisshammer R, Tate CG, Vaidehi N. Thermostabilization of the β1-adrenergic receptor correlates with increased entropy of the inactive state. The Journal of Physical Chemistry. B. 117: 7283-91. PMID 23697892 DOI: 10.1021/Jp403207C  1
2013 Christopher JA, Brown J, Doré AS, Errey JC, Koglin M, Marshall FH, Myszka DG, Rich RL, Tate CG, Tehan B, Warne T, Congreve M. Biophysical fragment screening of the β1-adrenergic receptor: identification of high affinity arylpiperazine leads using structure-based drug design. Journal of Medicinal Chemistry. 56: 3446-55. PMID 23517028 DOI: 10.1021/jm400140q  1
2013 Bennett KA, Tehan B, Lebon G, Tate CG, Weir M, Marshall FH, Langmead CJ. Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy. Molecular Pharmacology. 83: 949-58. PMID 23429888 DOI: 10.1124/mol.112.084509  1
2013 Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM. Molecular signatures of G-protein-coupled receptors. Nature. 494: 185-94. PMID 23407534 DOI: 10.1038/nature11896  1
2013 Warne T, Tate CG. The importance of interactions with helix 5 in determining the efficacy of β-adrenoceptor ligands. Biochemical Society Transactions. 41: 159-65. PMID 23356277 DOI: 10.1042/BST20120228  1
2013 Braunschweig H, Herbst T, Radacki K, Tate CW, Vargas A. Cyclic (amino)(imino)carbene complexes by borylene transfer to isocyanides. Chemical Communications (Cambridge, England). 49: 1702-4. PMID 23340804 DOI: 10.1039/C3Cc38379B  1
2013 Shibata Y, Gvozdenovic-Jeremic J, Love J, Kloss B, White JF, Grisshammer R, Tate CG. Optimising the combination of thermostabilising mutations in the neurotensin receptor for structure determination. Biochimica Et Biophysica Acta. 1828: 1293-301. PMID 23337476 DOI: 10.1016/J.Bbamem.2013.01.008  1
2013 Braunschweig H, Radacki K, Shang R, Tate CW. Reversible intramolecular coupling of the terminal borylene and a carbonyl ligand of [Cp(CO)2Mn=B-tBu]. Angewandte Chemie (International Ed. in English). 52: 729-33. PMID 23165638 DOI: 10.1002/Anie.201207017  1
2013 Andréll J, Tate CG. Overexpression of membrane proteins in mammalian cells for structural studies. Molecular Membrane Biology. 30: 52-63. PMID 22963530 DOI: 10.3109/09687688.2012.703703  1
2012 Lebon G, Tate CG. [G protein-coupled receptors in the spotlight]. MéDecine Sciences : M/S. 28: 876-82. PMID 23067420 DOI: 10.1051/medsci/20122810017  1
2012 White JF, Noinaj N, Shibata Y, Love J, Kloss B, Xu F, Gvozdenovic-Jeremic J, Shah P, Shiloach J, Tate CG, Grisshammer R. Structure of the agonist-bound neurotensin receptor. Nature. 490: 508-13. PMID 23051748 DOI: 10.1038/Nature11558  1
2012 Tate CG. A crystal clear solution for determining G-protein-coupled receptor structures. Trends in Biochemical Sciences. 37: 343-52. PMID 22784935 DOI: 10.1016/j.tibs.2012.06.003  1
2012 Owen RL, Axford D, Nettleship JE, Owens RJ, Robinson JI, Morgan AW, Doré AS, Lebon G, Tate CG, Fry EE, Ren J, Stuart DI, Evans G. Outrunning free radicals in room-temperature macromolecular crystallography. Acta Crystallographica. Section D, Biological Crystallography. 68: 810-8. PMID 22751666 DOI: 10.1107/S0907444912012553  1
2012 Warne T, Edwards PC, Leslie AG, Tate CG. Crystal structures of a stabilized β1-adrenoceptor bound to the biased agonists bucindolol and carvedilol. Structure (London, England : 1993). 20: 841-9. PMID 22579251 DOI: 10.1016/j.str.2012.03.014  1
2012 Lebon G, Warne T, Tate CG. Agonist-bound structures of G protein-coupled receptors. Current Opinion in Structural Biology. 22: 482-90. PMID 22480933 DOI: 10.1016/j.sbi.2012.03.007  1
2012 Scott CA, Atkinson SH, Sodha A, Tate C, Sadiq J, Lakhoo K, Pollard AJ. Management of lymphadenitis due to non-tuberculous mycobacterial infection in children. Pediatric Surgery International. 28: 461-6. PMID 22438045 DOI: 10.1007/s00383-012-3068-8  1
2012 Tate CW, deMello A, Gee AD, Kealey S, Vilar R, White AJ, Long NJ. Hemilabile and reversible carbon monoxide binding properties of iron(II), cobalt(II) and nickel(II) complexes containing a new tridentate P-S-N ligand. Dalton Transactions (Cambridge, England : 2003). 41: 83-9. PMID 22011880 DOI: 10.1039/C1Dt11248A  1
2011 Lebon G, Tate CG. [Structure of the adenosine-bound conformation of the human adenosine A(2A) receptor]. MéDecine Sciences : M/S. 27: 926-8. PMID 22130015 DOI: 10.1051/medsci/20112711004  1
2011 Miller JL, Tate CG. Engineering an ultra-thermostable β(1)-adrenoceptor. Journal of Molecular Biology. 413: 628-38. PMID 21907721 DOI: 10.1016/j.jmb.2011.08.057  1
2011 Doré AS, Robertson N, Errey JC, Ng I, Hollenstein K, Tehan B, Hurrell E, Bennett K, Congreve M, Magnani F, Tate CG, Weir M, Marshall FH. Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine. Structure (London, England : 1993). 19: 1283-93. PMID 21885291 DOI: 10.1016/j.str.2011.06.014  1
2011 Lebon G, Warne T, Edwards PC, Bennett K, Langmead CJ, Leslie AG, Tate CG. Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation. Nature. 474: 521-5. PMID 21593763 DOI: 10.1038/nature10136  1
2011 Baker JG, Proudman RG, Tate CG. The pharmacological effects of the thermostabilising (m23) mutations and intra and extracellular (β36) deletions essential for crystallisation of the turkey β-adrenoceptor. Naunyn-Schmiedeberg's Archives of Pharmacology. 384: 71-91. PMID 21547538 DOI: 10.1007/s00210-011-0648-4  1
2011 Moukhametzianov R, Warne T, Edwards PC, Serrano-Vega MJ, Leslie AG, Tate CG, Schertler GF. Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 108: 8228-32. PMID 21540331 DOI: 10.1073/pnas.1100185108  1
2011 Lebon G, Bennett K, Jazayeri A, Tate CG. Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor. Journal of Molecular Biology. 409: 298-310. PMID 21501622 DOI: 10.1016/j.jmb.2011.03.075  1
2011 Bill RM, Henderson PJ, Iwata S, Kunji ER, Michel H, Neutze R, Newstead S, Poolman B, Tate CG, Vogel H. Overcoming barriers to membrane protein structure determination. Nature Biotechnology. 29: 335-40. PMID 21478852 DOI: 10.1038/Nbt.1833  1
2011 Hovers J, Potschies M, Polidori A, Pucci B, Raynal S, Bonneté F, Serrano-Vega MJ, Tate CG, Picot D, Pierre Y, Popot JL, Nehmé R, Bidet M, Mus-Veteau I, Busskamp H, et al. A class of mild surfactants that keep integral membrane proteins water-soluble for functional studies and crystallization. Molecular Membrane Biology. 28: 171-81. PMID 21314479 DOI: 10.3109/09687688.2011.552440  1
2011 Warne T, Moukhametzianov R, Baker JG, Nehmé R, Edwards PC, Leslie AG, Schertler GF, Tate CG. The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor. Nature. 469: 241-4. PMID 21228877 DOI: 10.1038/nature09746  1
2010 Tate CG, Stevens RC. Growth and excitement in membrane protein structural biology. Current Opinion in Structural Biology. 20: 399-400. PMID 20702086 DOI: 10.1016/J.Sbi.2010.07.002  0.01
2010 Tate CG. Biochemistry. Membrane protein gymnastics. Science (New York, N.Y.). 328: 1644-5. PMID 20576878 DOI: 10.1126/science.1193065  0.01
2010 Korkhov VM, Sachse C, Short JM, Tate CG. Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals. Structure (London, England : 1993). 18: 677-87. PMID 20541505 DOI: 10.1016/j.str.2010.03.001  1
2010 Tate CG. Practical considerations of membrane protein instability during purification and crystallisation. Methods in Molecular Biology (Clifton, N.J.). 601: 187-203. PMID 20099147 DOI: 10.1007/978-1-60761-344-2_12  0.01
2009 Serrano-Vega MJ, Tate CG. Transferability of thermostabilizing mutations between beta-adrenergic receptors. Molecular Membrane Biology. 26: 385-96. PMID 19883298 DOI: 10.3109/09687680903208239  1
2009 Tate CG, Schertler GF. Engineering G protein-coupled receptors to facilitate their structure determination. Current Opinion in Structural Biology. 19: 386-95. PMID 19682887 DOI: 10.1016/j.sbi.2009.07.004  1
2009 Barrera NP, Isaacson SC, Zhou M, Bavro VN, Welch A, Schaedler TA, Seeger MA, Miguel RN, Korkhov VM, van Veen HW, Venter H, Walmsley AR, Tate CG, Robinson CV. Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions. Nature Methods. 6: 585-7. PMID 19578383 DOI: 10.1038/Nmeth.1347  1
2009 Shibata Y, White JF, Serrano-Vega MJ, Magnani F, Aloia AL, Grisshammer R, Tate CG. Thermostabilization of the neurotensin receptor NTS1. Journal of Molecular Biology. 390: 262-77. PMID 19422831 DOI: 10.1016/J.Jmb.2009.04.068  1
2009 Warne T, Serrano-Vega MJ, Tate CG, Schertler GF. Development and crystallization of a minimal thermostabilised G protein-coupled receptor. Protein Expression and Purification. 65: 204-13. PMID 19297694  1
2009 Korkhov VM, Tate CG. An emerging consensus for the structure of EmrE. Acta Crystallographica. Section D, Biological Crystallography. 65: 186-92. PMID 19171974 DOI: 10.1107/S0907444908036640  1
2008 Magnani F, Shibata Y, Serrano-Vega MJ, Tate CG. Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor. Proceedings of the National Academy of Sciences of the United States of America. 105: 10744-9. PMID 18664584 DOI: 10.1073/Pnas.0804396105  1
2008 Warne T, Serrano-Vega MJ, Baker JG, Moukhametzianov R, Edwards PC, Henderson R, Leslie AG, Tate CG, Schertler GF. Structure of a beta1-adrenergic G-protein-coupled receptor. Nature. 454: 486-91. PMID 18594507 DOI: 10.1038/Nature07101  1
2008 Korkhov VM, Tate CG. Electron crystallography reveals plasticity within the drug binding site of the small multidrug transporter EmrE. Journal of Molecular Biology. 377: 1094-103. PMID 18295794 DOI: 10.1016/j.jmb.2008.01.056  1
2008 Serrano-Vega MJ, Magnani F, Shibata Y, Tate CG. Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form. Proceedings of the National Academy of Sciences of the United States of America. 105: 877-82. PMID 18192400 DOI: 10.1073/Pnas.0711253105  1
2008 Tate CG, Rubinstein JL. Membrane Protein Structure Determination by Electron Cryo-Microscopy Biophysical Analysis of Membrane Proteins: Investigating Structure and Function. 29-54. DOI: 10.1002/9783527621224.ch2  1
2007 Kurkela M, Patana AS, Mackenzie PI, Court MH, Tate CG, Hirvonen J, Goldman A, Finel M. Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6. Pharmacogenetics and Genomics. 17: 115-26. PMID 17301691 DOI: 10.1097/Fpc.0B013E328011B598  0.01
2006 Boss SR, Coles MP, Eyre-Brook V, García F, Haigh R, Hitchcock PB, McPartlin M, Morey JV, Naka H, Raithby PR, Sparkes HA, Tate CW, Wheatley AE. Encapsulation of hydride by molecular main group metal clusters: manipulating the source and coordination sphere of the interstitial ion. Dalton Transactions (Cambridge, England : 2003). 5574-82. PMID 17225894 DOI: 10.1039/b612782g  0.01
2006 Fleishman SJ, Harrington SE, Enosh A, Halperin D, Tate CG, Ben-Tal N. Quasi-symmetry in the cryo-EM structure of EmrE provides the key to modeling its transmembrane domain. Journal of Molecular Biology. 364: 54-67. PMID 17005200 DOI: 10.1016/j.jmb.2006.08.072  1
2006 Roberts RC, Sutherland-Smith AJ, Wheeler MA, Jensen ON, Emerson LJ, Spiliotis II, Tate CG, Kendrick-Jones J, Ellis JA. The Emery-Dreifuss muscular dystrophy associated-protein emerin is phosphorylated on serine 49 by protein kinase A. The Febs Journal. 273: 4562-75. PMID 16972941 DOI: 10.1111/J.1742-4658.2006.05464.X  1
2006 Tate CG. Comparison of three structures of the multidrug transporter EmrE. Current Opinion in Structural Biology. 16: 457-64. PMID 16828280 DOI: 10.1016/j.sbi.2006.06.005  0.01
2004 Ilag LL, Ubarretxena-Belandia I, Tate CG, Robinson CV. Drug binding revealed by tandem mass spectrometry of a protein-micelle complex. Journal of the American Chemical Society. 126: 14362-3. PMID 15521749 DOI: 10.1021/ja0450307  1
2004 Magnani F, Tate CG, Wynne S, Williams C, Haase J. Partitioning of the serotonin transporter into lipid microdomains modulates transport of serotonin. The Journal of Biological Chemistry. 279: 38770-8. PMID 15226315 DOI: 10.1074/jbc.M400831200  0.01
2003 Ubarretxena-Belandia I, Baldwin JM, Schuldiner S, Tate CG. Three-dimensional structure of the bacterial multidrug transporter EmrE shows it is an asymmetric homodimer. The Embo Journal. 22: 6175-81. PMID 14633977 DOI: 10.1093/Emboj/Cdg611  1
2003 Tate CG, Ubarretxena-Belandia I, Baldwin JM. Conformational changes in the multidrug transporter EmrE associated with substrate binding. Journal of Molecular Biology. 332: 229-42. PMID 12946360 DOI: 10.1016/S0022-2836(03)00895-7  1
2003 Higgins MK, Demir M, Tate CG. Calnexin co-expression and the use of weaker promoters increase the expression of correctly assembled Shaker potassium channel in insect cells Biochimica Et Biophysica Acta - Biomembranes. 1610: 124-132. PMID 12586386 DOI: 10.1016/S0005-2736(02)00715-0  1
2001 Schuldiner S, Granot D, Mordoch SS, Ninio S, Rotem D, Soskin M, Tate CG, Yerushalmi H. Small is mighty: EmrE, a multidrug transporter as an experimental paradigm. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 16: 130-4. PMID 11443233  1
2001 Tate CG, Kunji ER, Lebendiker M, Schuldiner S. The projection structure of EmrE, a proton-linked multidrug transporter from Escherichia coli, at 7 A resolution. The Embo Journal. 20: 77-81. PMID 11226157 DOI: 10.1093/Emboj/20.1.77  1
1999 Tate CG, Whiteley E, Betenbaugh MJ. Molecular chaperones improve functional expression of the serotonin (5-hydroxytryptamine) transporter in insect cells Biochemical Society Transactions. 27: 932-936. PMID 10830131 DOI: 10.1042/Bst0270932  1
1999 Tate CG, Whiteley E, Betenbaugh MJ. Molecular chaperones stimulate the functional expression of the cocaine- sensitive serotonin transporter Journal of Biological Chemistry. 274: 17551-17558. PMID 10364189 DOI: 10.1074/Jbc.274.25.17551  1
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