Qian Cai, Ph.D - Publications

Affiliations: 
2001-2006 SIOC,CAS 
 2009-2016 Guangzhou Institutes Biomedicine and Health,CAS 
 2016- Jinan University 

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Qiu K, Wu K, Ma H, Ao Y, Zhou W, Cai Q. A transition-metal-free azide-alkyne cycloaddition/hydroamination cascade reaction for the construction of triazole-fused piperazin-2-ones. Organic & Biomolecular Chemistry. PMID 38206312 DOI: 10.1039/d3ob01999c  0.302
2022 Zhong X, Huang M, Xiong H, Liang Y, Zhou W, Cai Q. Asymmetric Synthesis of Spiro[Azetidine-3,3'-Indoline]-2,2'-Diones via Copper(I)-Catalyzed Kinugasa/C-C Coupling Cascade Reaction. Angewandte Chemie (International Ed. in English). PMID 36053546 DOI: 10.1002/anie.202208323  0.442
2021 Ma H, Feng J, Zhou W, Chen C, Deng Z, Zhou F, Ouyang Y, Zhang X, Cai Q. Copper(i)-catalyzed asymmetric intramolecular C-arylation with ureas as the additives: highly enantioselective formation of spirooxindoles. Organic & Biomolecular Chemistry. 19: 7480-7484. PMID 34612367 DOI: 10.1039/d1ob01327k  0.627
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Cai Q, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.555
2020 Liu J, Wang Y, Chen C, Tu Z, Zhu S, Zhou F, Si H, Zheng C, Zhang Z, Cai Q. Identification and Development of 1,4-Diaryl-1,2,3-triazolo-Based Ureas as Novel FLT3 Inhibitors. Acs Medicinal Chemistry Letters. 11: 1567-1572. PMID 32832025 DOI: 10.1021/acsmedchemlett.0c00216  0.452
2019 Liu T, Feng J, Chen C, Deng Z, Kotagiri R, Zhou G, Zhang X, Cai Q. Copper(I)-Catalyzed Intramolecular Asymmetric Double C-Arylation for the Formation of Chiral Spirocyclic Bis-oxindoles. Organic Letters. PMID 31184179 DOI: 10.1021/Acs.Orglett.9B01373  0.386
2019 Kotagiri R, Deng Z, Xu W, Cai Q. Stereospecific Synthesis of ( E)-5-Tetrasubstituted-ylidene-3,5-dihydro-4 H-imidazol-4-ones. Organic Letters. PMID 31140817 DOI: 10.1021/acs.orglett.9b01063  0.345
2018 Ding Q, He H, Cai Q. Chiral Aryliodine-Catalyzed Asymmetric Oxidative C-N Bond Formation via Desymmetrization Strategy. Organic Letters. PMID 30036067 DOI: 10.1021/acs.orglett.8b01849  0.353
2017 Zhang Y, Wang Q, Wang T, He H, Yang W, Zhang X, Cai Q. Enantioselective Synthesis of Chiral Oxygen-Containing Heterocycles Using Copper-Catalyzed Aryl C-O Coupling Reactions via Asymmetric Desymmetrization. The Journal of Organic Chemistry. PMID 28054776 DOI: 10.1021/Acs.Joc.6B02646  0.39
2017 An Y, He H, Liu T, Zhang Y, Lu X, Cai Q. Diversified Synthesis of 2-(4-Oxo[1,2,3]triazolo[1,5-a]quinoxalin-5(4H)-yl)acetamide Derivatives through Ugi-4-CR and Copper-Catalyzed Tandem Reactions Synthesis. 49: 3863-3873. DOI: 10.1055/S-0036-1590791  0.455
2016 Lu QP, Chen WD, Peng JR, Xu YD, Cai Q, Feng GK, Ding K, Zhu XF, Guan Z. Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells. Oncology Letters. 12: 3598-3608. PMID 27900042 DOI: 10.3892/ol.2016.5088  0.371
2016 Zhou F, Liu J, Cai Q. ChemInform Abstract: Transition Metal Catalyzed Asymmetric Aryl Carbon-Heteroatom Bond Coupling Reactions Cheminform. 47. DOI: 10.1002/CHIN.201620247  0.571
2016 Liu J, Tian Y, Shi J, Zhang S, Cai Q. ChemInform Abstract: An Enantioselective Synthesis of Spirobilactams Through Copper-Catalyzed Intramolecular Double N-Arylation and Phase Separation. Cheminform. 47: no-no. DOI: 10.1002/CHIN.201604137  0.386
2015 Zhou F, Cai Q. Recent advances in copper-catalyzed asymmetric coupling reactions. Beilstein Journal of Organic Chemistry. 11: 2600-15. PMID 26734106 DOI: 10.3762/bjoc.11.280  0.653
2015 Liu J, Tian Y, Shi J, Zhang S, Cai Q. An Enantioselective Synthesis of Spirobilactams through Copper-Catalyzed Intramolecular Double N-Arylation and Phase Separation. Angewandte Chemie (International Ed. in English). 54: 10917-20. PMID 26228798 DOI: 10.1002/anie.201504589  0.331
2015 Yang W, Liu Y, Zhang S, Cai Q. Copper-Catalyzed Intramolecular Desymmetric Aryl CO Coupling for the Enantioselective Construction of Chiral Dihydrobenzofurans and Dihydrobenzopyrans. Angewandte Chemie (International Ed. in English). 54: 8805-8. PMID 26060986 DOI: 10.1002/Anie.201503882  0.45
2015 He N, Huo Y, Liu J, Huang Y, Zhang S, Cai Q. Copper-catalyzed enantioselective intramolecular aryl C-N coupling: synthesis of enantioenriched 2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxamides via an asymmetric desymmetrization strategy. Organic Letters. 17: 374-7. PMID 25547539 DOI: 10.1021/Ol5035386  0.596
2015 Yang W, Liu Y, Zhang S, Cai Q. ChemInform Abstract: Copper-Catalyzed Intramolecular Desymmetric Aryl C-O Coupling for the Enantioselective Construction of Chiral Dihydrobenzofurans and Dihydrobenzopyrans. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201548118  0.341
2015 He N, Huo Y, Liu J, Huang Y, Zhang S, Cai Q. ChemInform Abstract: Copper-Catalyzed Enantioselective Intramolecular Aryl C-N Coupling: Synthesis of Enantioenriched 2-Oxo-1,2,3,4-tetrahydroquinoline-3-carboxamides via an Asymmetric Desymmetrization Strategy. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201523172  0.476
2015 Zhou F, Cheng G, Yang W, Long Y, Zhang S, Wu Y, Zhang X, Cai Q. ChemInform Abstract: Enantioselective Formation of Cyano-Bearing All-Carbon Quaternary Stereocenters: Desymmetrization by Copper-Catalyzed N-Arylation. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201508226  0.612
2014 Zhou F, Cheng GJ, Yang W, Long Y, Zhang S, Wu YD, Zhang X, Cai Q. Enantioselective formation of cyano-bearing all-carbon quaternary stereocenters: desymmetrization by copper-catalyzed N-arylation. Angewandte Chemie (International Ed. in English). 53: 9555-9. PMID 25045110 DOI: 10.1002/Anie.201405575  0.584
2014 Liu J, Yan J, Qin D, Cai Q. An Unexpected Inversion of Enantioselectivity in a Copper-Catalyzed Intramolecular­ Desymmetric Aryl C–N Coupling Reaction Synthesis. 46: 1917-1923. DOI: 10.1055/S-0033-1338638  0.481
2014 Liu J, Yan J, Qin D, Cai Q. ChemInform Abstract: An Unexpected Inversion of Enantioselectivity in a Copper-Catalyzed Intramolecular Desymmetric Aryl C-N Coupling Reaction. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201503128  0.53
2013 Yang W, Yan J, Long Y, Zhang S, Liu J, Zeng Y, Cai Q. Pd-catalyzed desymmetric intramolecular O-arylation reaction: enantioselective synthesis of (3,4-dihydro-2H-chromen-3-yl)methanols. Organic Letters. 15: 6022-5. PMID 24261632 DOI: 10.1021/ol402911y  0.364
2013 Yang W, Long Y, Zhang S, Zeng Y, Cai Q. Copper-catalyzed enantioselective intramolecular N-arylation, an efficient method for kinetic resolutions. Organic Letters. 15: 3598-601. PMID 23829519 DOI: 10.1021/Ol401449B  0.514
2013 Xu T, Zhang L, Xu S, Yang CY, Luo J, Ding F, Lu X, Liu Y, Tu Z, Li S, Pei D, Cai Q, Li H, Ren X, Wang S, et al. Pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives as selective inhibitors of EGFR threonine790 to methionine790 (T790M) mutants. Angewandte Chemie (International Ed. in English). 52: 8387-90. PMID 23804305 DOI: 10.1002/Anie.201302313  0.426
2013 Yan X, Liao J, Lu Y, Liu J, Zeng Y, Cai Q. Pd-catalyzed one-pot synthesis of polysubstituted acrylamidines from isocyanides, diazo compounds, and imines. Organic Letters. 15: 2478-81. PMID 23642149 DOI: 10.1021/Ol4009552  0.431
2013 Cai Q, Zhou F. Development and challenges in copper-catalyzed asymmetric Ullmann-type coupling reactions Synlett. 24: 408-411. DOI: 10.1055/S-0032-1317866  0.694
2013 Yang W, Long Y, Zhang S, Zeng Y, Cai Q. ChemInform Abstract: Copper-Catalyzed Enantioselective Intramolecular N-Arylation, an Efficient Method for Kinetic Resolution. Cheminform. 44: no-no. DOI: 10.1002/CHIN.201350169  0.403
2013 Zhou F, Guo J, Liu J, Ding K, Yu S, Cai Q. ChemInform Abstract: Copper-Catalyzed Desymmetric Intramolecular Ullmann C-N Coupling: An Enantioselective Preparation of Indolines. Cheminform. 44: no-no. DOI: 10.1002/CHIN.201309128  0.655
2012 Zhou F, Guo J, Liu J, Ding K, Yu S, Cai Q. Copper-catalyzed desymmetric intramolecular Ullmann C-N coupling: an enantioselective preparation of indolines. Journal of the American Chemical Society. 134: 14326-9. PMID 22913611 DOI: 10.1021/Ja306631Z  0.799
2012 Cai Q, Yan J, Ding K. A CuAAC/Ullmann C-C coupling tandem reaction: copper-catalyzed reactions of organic azides with N-(2-iodoaryl)propiolamides or 2-iodo-N-(prop-2-ynyl)benzenamines. Organic Letters. 14: 3332-5. PMID 22724380 DOI: 10.1021/Ol301307X  0.658
2012 Yan J, Zhou F, Qin D, Cai T, Ding K, Cai Q. Synthesis of [1,2,3]triazolo[1,5-a]quinoxalin-4(5H)-ones through copper-catalyzed tandem reactions of N-(2-haloaryl)propiolamides with sodium azide. Organic Letters. 14: 1262-5. PMID 22335274 DOI: 10.1021/Ol300114W  0.751
2012 Peng Y, Sun H, Lu J, Liu L, Cai Q, Shen R, Yang CY, Yi H, Wang S. Bivalent Smac mimetics with a diazabicyclic core as highly potent antagonists of XIAP and cIAP1/2 and novel anticancer agents. Journal of Medicinal Chemistry. 55: 106-14. PMID 22148838 DOI: 10.1021/Jm201072X  0.5
2012 Cai Q, Yan J, Ding K. ChemInform Abstract: A CuAAC/Ullmann C-C Coupling Tandem Reaction: Copper-Catalyzed Reactions of Organic Azides with N-(2-Iodoaryl)propiolamides or 2-Iodo-N-(prop-2-ynyl)benzenamines. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201244153  0.494
2012 Yan J, Zhou F, Qin D, Cai T, Ding K, Cai Q. ChemInform Abstract: Synthesis of [1,2,3]Triazolo[1,5-a]quinoxalin-4(5H)-ones Through Copper-Catalyzed Tandem Reactions of N-(2-Haloaryl)propiolamides with Sodium Azide. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201227169  0.66
2012 Zhou F, Ding K, Cai Q. ChemInform Abstract: Palladium-Catalyzed Amidation of N-Tosylhydrazones with Isocyanides. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201211061  0.625
2011 Zhou F, Ding K, Cai Q. Palladium-catalyzed amidation of N-tosylhydrazones with isocyanides. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 12268-71. PMID 21938752 DOI: 10.1002/Chem.201102459  0.711
2011 Zhou F, Liu J, Ding K, Liu J, Cai Q. Copper-catalyzed tandem reaction of isocyanides with N-(2-haloaryl)propiolamides for the synthesis of pyrrolo[3,2-c]quinolin-4-ones. The Journal of Organic Chemistry. 76: 5346-53. PMID 21591728 DOI: 10.1021/Jo2006939  0.752
2011 Cai Q, Sun H, Peng Y, Lu J, Nikolovska-Coleska Z, McEachern D, Liu L, Qiu S, Yang CY, Miller R, Yi H, Zhang T, Sun D, Kang S, Guo M, et al. A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment. Journal of Medicinal Chemistry. 54: 2714-26. PMID 21443232 DOI: 10.1021/Jm101505D  0.488
2011 Wang D, Zhang Z, Lu X, Feng Y, Luo K, Gan J, Yingxue L, Wan J, Li X, Zhang F, Tu Z, Cai Q, Ren X, Ding K. Hybrid compounds as new Bcr/Abl inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 1965-8. PMID 21376587 DOI: 10.1016/J.Bmcl.2011.02.029  0.453
2011 Cai Q, Zhou F, Xu T, Fu L, Ding K. Copper-catalyzed tandem reactions of 1-(2-iodoary)-2-yn-1-ones with isocyanides for the synthesis of 4-oxo-indeno[1,2-b]pyrroles. Organic Letters. 13: 340-343. PMID 21162591 DOI: 10.1021/Ol102826F  0.731
2011 Cai Q, Zhou F, Fu L, Wie J, Ding K. Synthesis of 4-Oxoindeno[1,2-b]pyrroles through Copper-Catalyzed Tandem Reactions of 1-(2-Haloaryl)enones with Isocyanides Synthesis. 2011: 3037-3044. DOI: 10.1055/S-0030-1260171  0.662
2011 Gao M, Liu X, Wang X, Cai Q, Ding K. Synthesis of 1-Aryl-1H-indazoles via a Ligand-Free Copper- Catalyzed Intramolecular Amination Reaction Chinese Journal of Chemistry. 29: 1199-1204. DOI: 10.1002/Cjoc.201190223  0.524
2011 Zhou F, Fu L, Wie J, Ding K, Cai Q. ChemInform Abstract: Synthesis of 4-Oxoindeno[1,2-b]pyrroles Through Copper-Catalyzed Tandem Reactions of 1-(2-Haloaryl)enones with Isocyanides. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201204099  0.629
2011 Zhou F, Liu J, Ding K, Liu J, Cai Q. ChemInform Abstract: Copper-Catalyzed Tandem Reaction of Isocyanides with N-(2-Haloaryl)propiolamides for the Synthesis of Pyrrolo[3,2-c]quinolin-4-ones. Cheminform. 42: no-no. DOI: 10.1002/CHIN.201148159  0.694
2011 Gao M, Liu X, Wang X, Cai Q, Ding K. ChemInform Abstract: Synthesis of 1-Aryl-1H-indazoles via a Ligand-Free Copper-Catalyzed Intramolecular Amination Reaction. Cheminform. 42: no-no. DOI: 10.1002/CHIN.201146122  0.412
2011 Cai Q, Zhou F, Xu T, Fu L, Ding K. ChemInform Abstract: Copper-Catalyzed Tandem Reactions of 1-(2-Iodoaryl)-2-yn-1-ones with Isocyanides for the Synthesis of 4-Oxo-indeno[1,2-b]pyrroles. Cheminform. 42: no-no. DOI: 10.1002/CHIN.201116112  0.63
2010 Cai Q, Li Z, Wei J, Fu L, Ha C, Pei D, Ding K. Synthesis of aza-fused polycyclic quinolines through copper-catalyzed cascade reactions. Organic Letters. 12: 1500-3. PMID 20196570 DOI: 10.1021/Ol1002225  0.674
2010 Cai Q, Ding K, Li Z, Fu L, Wei J, Ha C, Pei D. A Room-Temperature, Copper-Catalyzed Cascade Process for Diethyl 2-Aryl-3,4-dihydro-4-oxo-1,1(2H)-naphthalenedicarboxylate Synthesis. 2010: 3289-3294. DOI: 10.1055/S-0030-1257937  0.401
2010 Chen H, Wang D, Wang X, Huang W, Cai Q, Ding K. Mild Conditions for Copper-CatalyzedN-Arylation of Imidazoles Synthesis. 2010: 1505-1511. DOI: 10.1055/S-0029-1218691  0.514
2010 Cai Q, Li Z, Wei J, Fu L, Ha C, Pei D, Ding K. ChemInform Abstract: Synthesis of Aza-Fused Polycyclic Quinolines Through Copper-Catalyzed Cascade Reactions. Cheminform. 41: no-no. DOI: 10.1002/CHIN.201033154  0.443
2010 Wang D, Cai Q, Ding K. ChemInform Abstract: An Efficient Copper-Catalyzed Amination of Aryl Halides by Aqueous Ammonia. Cheminform. 41. DOI: 10.1002/CHIN.201002071  0.357
2009 Cai Q, Li Z, Wei J, Ha C, Pei D, Ding K. Assembly of indole-2-carboxylic acid esters through a ligand-free copper-catalysed cascade process. Chemical Communications (Cambridge, England). 7581-3. PMID 20024286 DOI: 10.1039/B918345K  0.616
2009 Cai Q, Zhang H, Zou B, Xie X, Zhu W, He G, Wang J, Pan X, Chen Y, Yuan Q, Liu F, Lu B, Ma D. Amino acid-promoted Ullmann-type coupling reactions and their applications in organic synthesis Pure and Applied Chemistry. 81: 227-234. DOI: 10.1351/Pac-Con-08-08-19  0.811
2009 Cai Q, Zhang H, Zou B, Xie X, Zhu W, He G, Wang J, Pan X, Chen Y, Yuan Q, et al. ea. ChemInform Abstract: Amino Acid Promoted Ullmann-Type Coupling Reactions and Their Applications in Organic Synthesis Cheminform. 40. DOI: 10.1002/CHIN.200933243  0.723
2009 Wang D, Cai Q, Ding K. An Efficient Copper-Catalyzed Amination of Aryl Halides by Aqueous Ammonia Advanced Synthesis & Catalysis. 351: 1722-1726. DOI: 10.1002/Adsc.200900327  0.513
2008 Peng Y, Sun H, Nikolovska-Coleska Z, Qiu S, Yang CY, Lu J, Cai Q, Yi H, Kang S, Yang D, Wang S. Potent, orally bioavailable diazabicyclic small-molecule mimetics of second mitochondria-derived activator of caspases. Journal of Medicinal Chemistry. 51: 8158-62. PMID 19049347 DOI: 10.1021/Jm801254R  0.492
2008 Sun H, Nikolovska-Coleska Z, Yang CY, Qian D, Lu J, Qiu S, Bai L, Peng Y, Cai Q, Wang S. Design of small-molecule peptidic and nonpeptidic Smac mimetics. Accounts of Chemical Research. 41: 1264-77. PMID 18937395 DOI: 10.1021/Ar8000553  0.5
2008 Ma D, Cai Q. Copper/amino acid catalyzed cross-couplings of aryl and vinyl halides with nucleophiles Accounts of Chemical Research. 41: 1450-1460. PMID 18698852 DOI: 10.1021/Ar8000298  0.685
2006 Cai Q, He G, Ma D. Mild and nonracemizing conditions for Ullmann-type diaryl ether formation between aryl iodides and tyrosine derivatives. The Journal of Organic Chemistry. 71: 5268-73. PMID 16808515 DOI: 10.1021/Jo0606960  0.706
2006 Cai Q, Zou B, Ma D. Mild Ullmann-type biaryl ether formation reaction by combination of ortho-substituent and ligand effects. Angewandte Chemie (International Ed. in English). 45: 1276-9. PMID 16425327 DOI: 10.1002/Anie.200503538  0.606
2005 Zhang H, Cai Q, Ma D. Amino acid promoted CuI-catalyzed C-N bond formation between aryl halides and amines or N-containing heterocycles. The Journal of Organic Chemistry. 70: 5164-73. PMID 15960520 DOI: 10.1021/Jo0504464  0.692
2005 Ma D, Cai Q, Xie X. CuI/N,N-Dimethylglycine-Catalyzed Cross-Coupling Reaction of Vinyl Halides with Phenols and Its Application to the Assembly of Substituted Benzofurans. Cheminform. 36. DOI: 10.1055/S-2005-871543  0.675
2005 Ma D, Cai Q, Zhu W, Zhang H, Zhang Y. Preparation ofN-Aryl Compounds by Amino Acid-Promoted Ullmann-Type Coupling Reactions Synthesis. 2005: 496-499. DOI: 10.1055/S-2004-831196  0.559
2005 Cai Q, Zhu W, Zhang H, Zhang Y, Ma D. Preparation of N-Aryl Compounds by Amino Acid-Promoted Ullmann-Type Coupling Reactions. Cheminform. 36. DOI: 10.1055/S-2004-831196  0.642
2004 Pan X, Cai Q, Ma D. CuI/N,N-dimethylglycine-catalyzed coupling of vinyl halides with amides or carbamates. Organic Letters. 6: 1809-12. PMID 15151420 DOI: 10.1021/Ol049464I  0.79
2004 Ma D, Cai Q. L-Proline Promoted Ullmann-Type Coupling Reactions of Aryl Iodides with Indoles, Pyrroles, Imidazoles or Pyrazoles. Cheminform. 35. DOI: 10.1055/S-2003-44995  0.652
2003 Ma D, Cai Q. N,N-Dimethyl Glycine-Promoted Ullmann Coupling Reaction of Phenols and Aryl Halides Organic Letters. 5: 3799-3802. PMID 14535713 DOI: 10.1021/Ol0350947  0.651
2003 Ma D, Cai Q, Zhang H. Mild method for Ullmann coupling reaction of amines and aryl halides. Organic Letters. 5: 2453-5. PMID 12841753 DOI: 10.1021/Ol0346584  0.688
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