Godfrey L. Smith, BSc, PhD - Publications

Affiliations: 
Physiology, then Inst of Cardiovascular & Medical Sci University of Glasgow, Glasgow, Scotland, United Kingdom 
Area:
cardiac muscle EC coupling

188 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Eisner D, Neher E, Taschenberger H, Smith G. Physiology of intracellular calcium buffering. Physiological Reviews. PMID 37326298 DOI: 10.1152/physrev.00042.2022  0.401
2023 Kuo CS, Dobi S, Gök C, Da Silva Costa A, Main A, Robertson-Gray O, Baptista-Hon D, Wypijewski KJ, Costello H, Hales TG, MacQuaide N, Smith GL, Fuller W. Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 120: e2207887120. PMID 36745790 DOI: 10.1073/pnas.2207887120  0.346
2020 Stølen TO, Høydal MA, Ahmed MS, Jørgensen K, Garten K, Hortigon-Vinagre MP, Zamora V, Scrimgeour NR, Berre AMO, Nes BM, Skogvoll E, Johnsen AB, Moreira JBN, McMullen JR, Attramadal H, ... Smith GL, et al. Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction. Journal of Molecular and Cellular Cardiology. 148: 106-119. PMID 32918915 DOI: 10.1016/J.Yjmcc.2020.08.015  0.353
2020 Błyszczuk P, Zuppinger C, Costa A, Nurzynska D, Di Meglio FD, Stellato M, Agarkova I, Smith GL, Distler O, Kania G. Activated Cardiac Fibroblasts Control Contraction of Human Fibrotic Cardiac Microtissues by a β-Adrenoreceptor-Dependent Mechanism. Cells. 9. PMID 32443848 DOI: 10.3390/Cells9051270  0.321
2020 Saleem U, van Meer BJ, Katili PA, Yusof NANM, Mannhardt I, Garcia AK, Tertoolen L, de Korte T, Vlaming MLH, McGlynn K, Nebel J, Bahinski A, Harris K, Rossman E, Xu X, ... ... Smith GL, et al. Blinded, multi-centre evaluation of drug-induced changes in contractility using human induced pluripotent stem cell-derived cardiomyocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32421822 DOI: 10.1093/Toxsci/Kfaa058  0.321
2020 Dietrichs ES, McGlynn K, Allan A, Connolly A, Bishop M, Burton F, Kettlewell S, Myles R, Tveita T, Smith GL. Moderate but not severe hypothermia causes pro-arrhythmic changes in cardiac electrophysiology. Cardiovascular Research. PMID 32031595 DOI: 10.1093/Cvr/Cvz309  0.33
2019 McGlynn K, Firth K, MacQuaide N, Smith G. Comparison of the effects of omecamtiv mercabil on excitation contraction coupling between isolated rabbit ventricular myocytes and human iPSC-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31963062 DOI: 10.1016/J.Vascn.2019.05.039  0.318
2019 Salerno S, Garten K, Smith GL, Stølen T, Kelly A. Two-photon excitation of FluoVolt allows improved interrogation of transmural electrophysiological function in the intact mouse heart. Progress in Biophysics and Molecular Biology. PMID 31492464 DOI: 10.1016/J.Pbiomolbio.2019.08.007  0.305
2019 Kettlewell S, Saxena P, Dempster J, Colman MA, Myles RC, Smith GL, Workman AJ. Dynamic-clamping human and rabbit atrial calcium current: narrowing I window abolishes early afterdepolarisations. The Journal of Physiology. PMID 31093979 DOI: 10.1113/Jp277827  0.342
2019 Smith GL, Eisner DA. Calcium Buffering in the Heart in Health and Disease. Circulation. 139: 2358-2371. PMID 31082292 DOI: 10.1161/Circulationaha.118.039329  0.471
2018 Lemme M, Ulmer BM, Lemoine MD, Zech ATL, Flenner F, Ravens U, Reichenspurner H, Rol-Garcia M, Smith G, Hansen A, Christ T, Eschenhagen T. Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium. Stem Cell Reports. 11: 1378-1390. PMID 30416051 DOI: 10.1016/J.Stemcr.2018.10.008  0.302
2018 Ghouri IA, Kelly A, Salerno S, Garten K, Stølen T, Smith GL. Characterization of Electrical Activity in Post-myocardial Infarction Scar Tissue in Rat Hearts Using Multiphoton Microscopy. Frontiers in Physiology. 9: 1454. PMID 30386255 DOI: 10.3389/Fphys.2018.01454  0.334
2018 van Meer BJ, Sala L, Tertoolen LGJ, Smith GL, Burton FL, Mummery CL. Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell-Derived Cardiomyocytes to Zebrafish and Human Hearts. Current Protocols in Human Genetics. e67. PMID 30253059 DOI: 10.1002/Cphg.67  0.325
2018 Høydal MA, Kirkeby-Garstad I, Karevold A, Wiseth R, Haaverstad R, Wahba A, Stølen TL, Contu R, Condorelli G, Ellingsen Ø, Smith GL, Kemi OJ, Wisløff U. Human cardiomyocyte calcium handling and transverse tubules in mid-stage of post-myocardial-infarction heart failure. Esc Heart Failure. PMID 29431258 DOI: 10.1002/Ehf2.12271  0.356
2018 Hortigon-Vinagre MP, Zamora V, Burton FL, Butler P, Smith GL. Measurements of voltage, intracellular Ca2+ and contraction from spontaneous iPSC-derived cardiomyocytes using CellOPTIQ® platform reveals complex effects from drugs that parallel in vivo cardiac effects Journal of Pharmacological and Toxicological Methods. 93: 119-120. DOI: 10.1016/J.Vascn.2018.01.407  0.454
2018 McGlynn KP, LaChaud Q, Burton FL, Smith GL. Measurements of action potentials, intracellular Ca2+ and contraction in stimulated isolated adult cardiomyocytes using CellOPTIQ® platform for lead development screening Journal of Pharmacological and Toxicological Methods. 93: 119. DOI: 10.1016/J.Vascn.2018.01.406  0.42
2018 Saxena P, Smith G, Macquaide N. Early Diastolic Ca2+ Sparks Alter Repolarization Rate of Rabbit Cardiomyocytes Biophysical Journal. 114: 288a. DOI: 10.1016/J.Bpj.2017.11.1653  0.466
2017 Sala L, van Meer BJ, Tertoolen LT, Bakkers J, Bellin M, Davis RP, Denning CN, Dieben MA, Eschenhagen T, Giacomelli E, Grandela C, Hansen A, Holman E, Jongbloed MR, Kamel SM, ... ... Smith G, et al. MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo. Circulation Research. PMID 29282212 DOI: 10.1161/Circresaha.117.312067  0.347
2017 Boyden PA, Smith GL. Ca(2+) leak, what is it? Why should we care? Can it be managed? Heart Rhythm. PMID 29157722 DOI: 10.1016/J.Hrthm.2017.11.018  0.424
2017 McCarroll CS, He W, Foote K, Bradley A, McGlynn K, Vidler F, Nixon C, Nather K, Fattah C, Riddell AH, Bowman P, Elliott EB, Bell M, Hawksby C, MacKenzie SM, ... ... Smith GL, et al. Runx1 Deficiency Protects Against Adverse Cardiac Remodeling Following Myocardial Infarction. Circulation. PMID 29030345 DOI: 10.1161/Circulationaha.117.028911  0.355
2017 Duncan G, Firth K, George V, Hoang MD, Staniforth A, Smith G, Denning C. Drug-mediated shortening of action potentials in LQTS2 human induced pluripotent stem cell-derived cardiomyocytes. Stem Cells and Development. PMID 28992755 DOI: 10.1089/Scd.2017.0172  0.312
2017 Lu HR, Hortigon-Vinagre MP, Zamora V, Kopljar I, De Bondt A, Gallacher DJ, Smith G. Application of optical action potentials in human induced pluripotent stem cells-derived cardiomyocytes to predict drug-induced cardiac arrhythmias. Journal of Pharmacological and Toxicological Methods. PMID 28501647 DOI: 10.1016/J.Vascn.2017.05.001  0.302
2016 Weinberger F, Breckwoldt K, Pecha S, Kelly A, Geertz B, Starbatty J, Yorgan T, Cheng KH, Lessmann K, Stolen T, Scherrer-Crosbie M, Smith G, Reichenspurner H, Hansen A, Eschenhagen T. Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells. Science Translational Medicine. 8: 363ra148. PMID 27807283 DOI: 10.1126/Scitranslmed.Aaf8781  0.329
2016 Hortigon-Vinagre MP, Zamora V, Burton FL, Green J, Gintant GA, Smith GL. The use of ratiometric fluorescence measurements of the voltage sensitive dye di-4-ANEPPS to examine action potential characteristics and drug effects on human induced pluripotent stem cell-derived cardiomyocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27621282 DOI: 10.1093/Toxsci/Kfw171  0.315
2016 Høydal MA, Stølen TO, Kettlewell S, Maier LS, Brown JH, Sowa T, Catalucci D, Condorelli G, Kemi OJ, Smith GL, Wisløff U. Exercise training reverses myocardial dysfunction induced by CaMKIIδC overexpression by restoring Ca2+-homeostasis. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00188.2016. PMID 27231311 DOI: 10.1152/Japplphysiol.00188.2016  0.472
2016 Nisbet AM, Camelliti P, Walker NL, Burton FL, Cobbe SM, Kohl P, Smith GL. Prolongation of atrio-ventricular nodal conduction in a rabbit model of ischaemic cardiomyopathy: Role of fibrosis and connexin remodelling. Journal of Molecular and Cellular Cardiology. PMID 27021518 DOI: 10.1016/J.Yjmcc.2016.03.011  0.339
2016 Saxena P, Hortigon-Vinagre M, Beyl S, Baburin I, Costa A, IJzerman AP, Kügler P, Timin E, Smith G, Hering S. On the Relation between HERG Channel Block in Cell Line and Action Potential Prolongation in Human iPSC Cardiomyocytes Biophysical Journal. 110: 527a. DOI: 10.1016/J.Bpj.2015.11.2819  0.306
2015 McArthur L, Chilton L, Smith GL, Nicklin SA. Electrical consequences of cardiac myocyte: fibroblast coupling. Biochemical Society Transactions. 43: 513-8. PMID 26009200 DOI: 10.1042/Bst20150035  0.33
2015 Smith GL, MacQuaide N. The direct actions of flecainide on the human cardiac ryanodine receptor: keeping open the debate on the mechanism of action of local anesthetics in CPVT. Circulation Research. 116: 1284-6. PMID 25858058 DOI: 10.1161/Circresaha.115.306298  0.442
2015 Hohendanner F, Walther S, Maxwell JT, Kettlewell S, Awad S, Smith GL, Lonchyna VA, Blatter LA. Inositol-1,4,5-trisphosphate induced Ca2+ release and excitation-contraction coupling in atrial myocytes from normal and failing hearts. The Journal of Physiology. 593: 1459-77. PMID 25416623 DOI: 10.1113/Jphysiol.2014.283226  0.517
2015 Ghouri IA, Kelly A, Burton FL, Smith GL, Kemi OJ. 2-photon excitation fluorescence microscopy enables deeper high-resolution imaging of voltage and Ca(2+) in intact mice, rat, and rabbit hearts. Journal of Biophotonics. 8: 112-23. PMID 24123976 DOI: 10.1002/Jbio.201300109  0.477
2015 Kelly A, Stølen TO, Solvang-Garten K, Charpentier F, Wisløff U, Smith GL. Abnormalities in Transmural Ventricular Electrophysiology in a Heterozygous SCN5A Knockout Mouse Model Revealed by Two-Photon Microscopy Biophysical Journal. 108: 274a. DOI: 10.1016/J.Bpj.2014.11.1502  0.327
2014 Campbell AS, Johnstone SR, Baillie GS, Smith G. β-Adrenergic modulation of myocardial conduction velocity: Connexins vs. sodium current. Journal of Molecular and Cellular Cardiology. 77: 147-54. PMID 25453599 DOI: 10.1016/J.Yjmcc.2014.09.030  0.344
2014 Boyman L, Chikando AC, Williams GS, Khairallah RJ, Kettlewell S, Ward CW, Smith GL, Kao JP, Lederer WJ. Calcium movement in cardiac mitochondria. Biophysical Journal. 107: 1289-301. PMID 25229137 DOI: 10.1016/J.Bpj.2014.07.045  0.484
2014 Nisbet AM, Burton FL, Walker NL, Craig MA, Cheng H, Hancox JC, Orchard CH, Smith GL. Acidosis slows electrical conduction through the atrio-ventricular node. Frontiers in Physiology. 5: 233. PMID 25009505 DOI: 10.3389/Fphys.2014.00233  0.308
2014 Haviland S, Cleemann L, Kettlewell S, Smith GL, Morad M. Diversity of mitochondrial Ca²⁺ signaling in rat neonatal cardiomyocytes: evidence from a genetically directed Ca²⁺ probe, mitycam-E31Q. Cell Calcium. 56: 133-46. PMID 24994483 DOI: 10.1016/J.Ceca.2014.06.001  0.468
2014 O-Uchi J, Jhun BS, Xu S, Hurst S, Raffaello A, Liu X, Yi B, Zhang H, Gross P, Mishra J, Ainbinder A, Kettlewell S, Smith GL, Dirksen RT, Wang W, et al. Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter. Antioxidants & Redox Signaling. 21: 863-79. PMID 24800979 DOI: 10.1089/Ars.2013.5394  0.432
2014 Liu T, Takimoto E, Dimaano VL, DeMazumder D, Kettlewell S, Smith G, Sidor A, Abraham TP, O'Rourke B. Inhibiting mitochondrial Na+/Ca2+ exchange prevents sudden death in a Guinea pig model of heart failure. Circulation Research. 115: 44-54. PMID 24780171 DOI: 10.1161/Circresaha.115.303062  0.438
2014 Høydal MA, Stølen TO, Johnsen AB, Alvez M, Catalucci D, Condorelli G, Koch LG, Britton SL, Smith GL, Wisløff U. Reduced aerobic capacity causes leaky ryanodine receptors that trigger arrhythmia in a rat strain artificially selected and bred for low aerobic running capacity. Acta Physiologica (Oxford, England). 210: 854-64. PMID 24444142 DOI: 10.1111/Apha.12238  0.348
2014 Campbell AS, Burton FL, Baillie GS, Smith GL. Action Potential Conduction Velocity is Increased by Raised Intracellular Camp in the Intact Rat Heart via a CaMKII Mediated Pathway Biophysical Journal. 106: 119a. DOI: 10.1016/J.Bpj.2013.11.716  0.305
2014 Hortigon-Vinagre MP, Low EL, Ghouri IA, Wallis R, Burton FL, Craig MA, Anson BD, Smith GL. Combine use of Intracellular Calcium and Sarcolemma Voltage Measurements to Distinguish Mixed Channel Effects in Human Induced Plutipotent Stem Cells Derived Cardiomyocytes (HIPSC-CMS) Biophysical Journal. 106: 720a. DOI: 10.1016/J.Bpj.2013.11.3979  0.404
2014 Kemi OJ, Johnston AS, Smith GL. Cardiomyocyte Calcium Handling Dysfunction at High Stimulation Frequencies; Increase in Post-Myocardial Infarction Heart Failure and Decrease by Exercise Training Biophysical Journal. 106: 447a. DOI: 10.1016/J.Bpj.2013.11.2536  0.428
2013 Høydal MA, Kaurstad G, Rolim NP, Johnsen AB, Alves M, Koch LG, Britton SL, Stølen TO, Smith GL, Wisløff U. High inborn aerobic capacity does not protect the heart following myocardial infarction. Journal of Applied Physiology (Bethesda, Md. : 1985). 115: 1788-95. PMID 24177693 DOI: 10.1152/Japplphysiol.00312.2013  0.482
2013 Johnsen AB, Rolim NP, Stølen T, Alves M, Sousa MM, Slupphaug G, Britton SL, Koch LG, Smith GL, Wisløff U, Høydal MA. Atrial myocyte function and Ca2+ handling is associated with inborn aerobic capacity. Plos One. 8: e76568. PMID 24146891 DOI: 10.1371/Journal.Pone.0076568  0.385
2013 O-Uchi J, Jhun BS, Hurst S, Bisetto S, Gross P, Chen M, Kettlewell S, Park J, Oyamada H, Smith GL, Murayama T, Sheu SS. Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca2+-induced ATP production in cardiac H9c2 myoblasts. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1736-51. PMID 24124188 DOI: 10.1152/Ajpheart.00094.2013  0.407
2013 Saraiva N, Prole DL, Carrara G, Johnson BF, Taylor CW, Parsons M, Smith GL. hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+ entry and calpain 2. The Journal of Cell Biology. 202: 699-713. PMID 23940116 DOI: 10.1083/Jcb.201301016  0.31
2013 Elliott EB, McCarroll D, Hasumi H, Welsh CE, Panissidi AA, Jones NG, Rossor CL, Tait A, Smith GL, Mottram JC, Morrison LJ, Loughrey CM. Trypanosoma brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes. Cardiovascular Research. 100: 325-35. PMID 23892734 DOI: 10.1093/Cvr/Cvt187  0.362
2013 Kettlewell S, Burton FL, Smith GL, Workman AJ. Chronic myocardial infarction promotes atrial action potential alternans, afterdepolarizations, and fibrillation. Cardiovascular Research. 99: 215-24. PMID 23568957 DOI: 10.1016/J.Jelectrocard.2013.05.032  0.353
2013 Lu X, Ginsburg KS, Kettlewell S, Bossuyt J, Smith GL, Bers DM. Measuring local gradients of intramitochondrial [Ca(2+)] in cardiac myocytes during sarcoplasmic reticulum Ca(2+) release. Circulation Research. 112: 424-31. PMID 23243207 DOI: 10.1161/Circresaha.111.300501  0.493
2013 Di Diego JM, Sicouri S, Myles RC, Burton FL, Smith GL, Antzelevitch C. Optical and electrical recordings from isolated coronary-perfused ventricular wedge preparations. Journal of Molecular and Cellular Cardiology. 54: 53-64. PMID 23142540 DOI: 10.1016/J.Yjmcc.2012.10.017  0.325
2013 Kelly A, Smith G. Intramural LV afterdepolarisations and arrhythmias during calcium overload in the intact rabbit heart Journal of Electrocardiology. 46: e32-e33. DOI: 10.1016/J.Jelectrocard.2013.05.120  0.327
2013 Johnston AS, Dunne M, Smith GL, Kemi OJ. Post-Myocardial Infarction Exercise Training Reverses Cardiac Excitation-Contraction Coupling Abnormalities by Activating Cytoplasmic CaMKII Biophysical Journal. 104: 106a. DOI: 10.1016/J.Bpj.2012.11.620  0.44
2013 Haviland S, Kettlewell S, Smith G, Cleemann L, Morad M. A New Approach to Evaluation of Mitochondrial Ca-Signaling in Cardiomyocytes Biophysical Journal. 104: 616a. DOI: 10.1016/J.Bpj.2012.11.3411  0.457
2013 Boyman L, Williams GS, Khairallah RJ, Chikando A, Hagen BM, Kettlewell S, Smith GL, Lederer WJ. Mitochondrial Ca2+ Dynamics in the Heart Biophysical Journal. 104: 605a. DOI: 10.1016/J.Bpj.2012.11.3355  0.502
2013 Chikando A, Boyman L, Khairallah R, Williams GS, Kettlewell S, Ward C, Smith GL, Kao J, Lederer WJ. ROS and Mitochondrial Membrane Potential Dependent Modulation of Calcium Signaling in the Heart Biophysical Journal. 104: 361a. DOI: 10.1016/J.Bpj.2012.11.2007  0.474
2012 Cheng H, Smith GL, Orchard CH, Hancox JC, Burton FL. Inhibition of sarcoplasmic reticulum Ca(2+)-ATPase decreases atrioventricular node-paced heart rate in rabbits. Experimental Physiology. 97: 1131-9. PMID 22562813 DOI: 10.1113/Expphysiol.2012.065110  0.377
2012 Elliott EB, Kelly A, Smith GL, Loughrey CM. Isolated rabbit working heart function during progressive inhibition of myocardial SERCA activity. Circulation Research. 110: 1618-27. PMID 22556337 DOI: 10.1161/Circresaha.111.262337  0.43
2012 Kelly A, Elliott EB, Matsuda R, Kaneko N, Smith GL, Loughrey CM. The effect of K201 on isolated working rabbit heart mechanical function during pharmacologically induced Ca2+ overload. British Journal of Pharmacology. 165: 1068-83. PMID 21658026 DOI: 10.1111/J.1476-5381.2011.01531.X  0.465
2012 Kemi OJ, MacQuaide N, Hoydal MA, Ellingsen O, Smith GL, Wisloff U. Exercise training corrects control of spontaneous calcium waves in hearts from myocardial infarction heart failure rats. Journal of Cellular Physiology. 227: 20-6. PMID 21465470 DOI: 10.1002/Jcp.22771  0.475
2012 Chikando AC, Boyman L, Khairallah R, Ward C, Smith G, Kao J, Lederer W. ROS Dependent Modulation of Calcium Sparks in Cardiomyocytes Biophysical Journal. 102: 99a. DOI: 10.1016/J.Bpj.2011.11.563  0.476
2012 Boyman L, Hagen BM, Khairallah RJ, Chikando A, Kettlewell S, Smith GL, Lederer W. Dynamics of Calcium Uptake and Release by the Mitochondria in the Heart Biophysical Journal. 102: 312a. DOI: 10.1016/J.Bpj.2011.11.1717  0.504
2011 Biesmans L, Macquaide N, Heinzel FR, Bito V, Smith GL, Sipido KR. Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density. Plos One. 6: e25100. PMID 22022376 DOI: 10.1371/Journal.Pone.0025100  0.495
2011 Elliott EB, Hasumi H, Otani N, Matsuda T, Matsuda R, Kaneko N, Smith GL, Loughrey CM. K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca(2+) release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes. Basic Research in Cardiology. 106: 1009-22. PMID 21901290 DOI: 10.1007/S00395-011-0218-4  0.472
2011 Chikando AC, Kettlewell S, Williams GS, Smith G, Lederer WJ. Ca2+ dynamics in the mitochondria - state of the art. Journal of Molecular and Cellular Cardiology. 51: 627-31. PMID 21864537 DOI: 10.1016/J.Yjmcc.2011.08.003  0.465
2011 Currie S, Elliott EB, Smith GL, Loughrey CM. Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention-An in vivo perspective. Pharmacology & Therapeutics. 131: 204-20. PMID 21414358 DOI: 10.1016/J.Pharmthera.2011.02.006  0.391
2011 Workman AJ, Smith GL, Rankin AC. Mechanisms of termination and prevention of atrial fibrillation by drug therapy. Pharmacology & Therapeutics. 131: 221-41. PMID 21334377 DOI: 10.1016/J.Pharmthera.2011.02.002  0.331
2011 Cheng H, Smith GL, Hancox JC, Orchard CH. Inhibition of spontaneous activity of rabbit atrioventricular node cells by KB-R7943 and inhibitors of sarcoplasmic reticulum Ca(2+) ATPase. Cell Calcium. 49: 56-65. PMID 21163524 DOI: 10.1016/J.Ceca.2010.11.008  0.477
2011 Myles RC, Burton FL, Cobbe SM, Smith GL. Alternans of action potential duration and amplitude in rabbits with left ventricular dysfunction following myocardial infarction. Journal of Molecular and Cellular Cardiology. 50: 510-21. PMID 21145895 DOI: 10.1016/J.Yjmcc.2010.11.019  0.323
2010 Smith G, Reynolds M, Burton F, Kemi OJ. Confocal and multiphoton imaging of intracellular Ca(2+). Methods in Cell Biology. 99: 225-61. PMID 21035689 DOI: 10.1016/B978-0-12-374841-6.00009-8  0.462
2010 MacQuaide N, Ramay HR, Sobie EA, Smith GL. Differential sensitivity of Ca2+ wave and Ca2+ spark events to ruthenium red in isolated permeabilised rabbit cardiomyocytes Journal of Physiology. 588: 4731-4742. PMID 20921197 DOI: 10.1113/Jphysiol.2010.193375  0.488
2010 Myles RC, Bernus O, Burton FL, Cobbe SM, Smith GL. Effect of activation sequence on transmural patterns of repolarization and action potential duration in rabbit ventricular myocardium. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1812-22. PMID 20889843 DOI: 10.1152/Ajpheart.00518.2010  0.308
2010 Cheng W, Klauke N, Smith G, Cooper JM. Microfluidic cell arrays for metabolic monitoring of stimulated cardiomyocytes. Electrophoresis. 31: 1405-13. PMID 20333720 DOI: 10.1002/Elps.200900579  0.344
2010 Zamparelli C, Macquaide N, Colotti G, Verzili D, Seidler T, Smith GL, Chiancone E. Activation of the cardiac Na(+)-Ca(2+) exchanger by sorcin via the interaction of the respective Ca(2+)-binding domains. Journal of Molecular and Cellular Cardiology. 49: 132-41. PMID 20298697 DOI: 10.1016/J.Yjmcc.2010.03.003  0.436
2010 Craig MA, McBride MW, Smith G, George SJ, Baker A. Dysregulation of cadherins in the intercalated disc of the spontaneously hypertensive stroke-prone rat. Journal of Molecular and Cellular Cardiology. 48: 1121-8. PMID 20138888 DOI: 10.1016/J.Yjmcc.2010.01.017  0.343
2010 Miller DJ, Smith GL. Lüttgau & Niedergerke; the classic study of calcium-sodium antagonism half a century on. The Journal of Physiology. 588: 23-5. PMID 20045904 DOI: 10.1113/Jphysiol.2009.184242  0.601
2010 Toischer K, Lehnart SE, Tenderich G, Milting H, Körfer R, Schmitto JD, Schöndube FA, Kaneko N, Loughrey CM, Smith GL, Hasenfuss G, Seidler T. K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulum. Basic Research in Cardiology. 105: 279-87. PMID 19718543 DOI: 10.1007/S00395-009-0057-8  0.45
2009 Fowler MR, Smith GL. The cardiac contraction cycle: is Ca2+ going local? Point. Journal of Applied Physiology (Bethesda, Md. : 1985). 107: 1981-4. PMID 19952385 DOI: 10.1152/Japplphysiol.91168.2009  0.506
2009 Stølen TO, Høydal MA, Kemi OJ, Catalucci D, Ceci M, Aasum E, Larsen T, Rolim N, Condorelli G, Smith GL, Wisløff U. Interval training normalizes cardiomyocyte function, diastolic Ca2+ control, and SR Ca2+ release synchronicity in a mouse model of diabetic cardiomyopathy. Circulation Research. 105: 527-36. PMID 19679837 DOI: 10.1161/Circresaha.109.199810  0.395
2009 Klauke N, Smith G, Cooper JM. Local regional stimulation of single isolated ventricular myocytes using microfluidics Analytical Chemistry. 81: 6390-6398. PMID 19572561 DOI: 10.1021/Ac9008429  0.314
2009 MacQuaide N, Dempster J, Smith GL. Assessment of sarcoplasmic reticulum Ca2+ depletion during spontaneous Ca2+ waves in isolated permeabilized rabbit ventricular cardiomyocytes. Biophysical Journal. 96: 2744-54. PMID 19348757 DOI: 10.1016/J.Bpj.2008.12.3944  0.479
2009 Kettlewell S, Seidler T, Smith GL. The effects of over-expression of the FK506-binding protein FKBP12.6 on K+ currents in adult rabbit ventricular myocytes Pflugers Archiv European Journal of Physiology. 458: 653-660. PMID 19333617 DOI: 10.1007/S00424-009-0666-Y  0.307
2009 Fowler MR, Smith GL. The cardiac contraction cycle: Is Ca2+ going local? Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 19299570 DOI: 10.1152/japplphysiol.91168.2008  0.37
2009 Kettlewell S, Cabrero P, Nicklin SA, Dow JA, Davies S, Smith GL. Changes of intra-mitochondrial Ca2+ in adult ventricular cardiomyocytes examined using a novel fluorescent Ca2+ indicator targeted to mitochondria. Journal of Molecular and Cellular Cardiology. 46: 891-901. PMID 19249308 DOI: 10.1016/J.Yjmcc.2009.02.016  0.469
2009 Masson R, Nicklin SA, Craig MA, McBride M, Gilday K, Gregorevic P, Allen JM, Chamberlain JS, Smith G, Graham D, Dominiczak AF, Napoli C, Baker AH. Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2. Hypertension. 53: 694-700. PMID 19221212 DOI: 10.1161/Hypertensionaha.108.122333  0.323
2009 Cheng H, Smith GL, Orchard CH, Hancox JC. Acidosis inhibits spontaneous activity and membrane currents in myocytes isolated from the rabbit atrioventricular node Journal of Molecular and Cellular Cardiology. 46: 75-85. PMID 18950636 DOI: 10.1016/J.Yjmcc.2008.09.709  0.378
2009 Fowler MR, Colotti G, Chiancone E, Higuchi Y, Seidler T, Smith GL. Complex modulation of L-type Ca(2+) current inactivation by sorcin in isolated rabbit cardiomyocytes. Pflã¼Gers Archiv : European Journal of Physiology. 457: 1049-60. PMID 18830620 DOI: 10.1007/S00424-008-0575-5  0.474
2009 Kemi OJ, MacQuaide N, Hoydal MA, Haram PM, Ellingsen O, Smith GL, Wisloff U. Exercise Training Corrects Control Of Diastolic Calcium In Hearts From Myocardial Infarction Heart Failure Rats Medicine & Science in Sports & Exercise. 41: 174. DOI: 10.1249/01.Mss.0000355086.27397.A8  0.312
2009 Fowler MR, Smith GL. Last word on viewpoint: The cardiac contraction cycle: Is Ca2+ going local? Journal of Applied Physiology. 107: 1988. DOI: 10.1152/Japplphysiol.01088.2009  0.486
2009 Stølen TO, Høydal MA, Brown JH, Maier LS, Smith GL, Wisløff U. Endurance Training Abolish Arrhythmogenic Ca2+ Leak In Cardiomyocytes From Mice Over-expressing CaMKII Biophysical Journal. 96: 110a. DOI: 10.1016/J.Bpj.2008.12.480  0.44
2009 Reynolds M, MacQuaide N, Thomas M, Smith G. UV Ratiometric Imaging Of Isolated Ventricular Cardiomyocytes Using An LED Based Illuminator Biophysical Journal. 96: 638a. DOI: 10.1016/J.Bpj.2008.12.3373  0.415
2009 Kettlewell S, Davies SA, Dow JT, Smith GL. Correlation Of Levels And Time Course Of Intracellular And Mitochondrial Calcium Signals In Isolated Adult Cardiac Cells Biophysical Journal. 96: 625a. DOI: 10.1016/J.Bpj.2008.12.3303  0.494
2009 Elliott EB, Kelly A, Rankin A, Smith GL, Loughrey CM. A Quantitative Assessment Of Selective Pharmacological Inhibition Of Serca In Isolated Rabbit Working Hearts Biophysical Journal. 96: 515a. DOI: 10.1016/J.Bpj.2008.12.2653  0.35
2009 Macquaide N, Anthony DF, Currie S, Smith GL. Upregulation Of Cam Kinase IIδ Modulates Spontaneous Ca2+ Wave Properties In A Rabbit Model Of Heart Failure Biophysical Journal. 96: 275a. DOI: 10.1016/J.Bpj.2008.12.1360  0.478
2009 Kemi OJ, MacQuaide N, Hoydal MA, Haram PM, Ellingsen O, Wisloff U, Smith GL. Exercise Training Reduces Spontaneous Ca2+ Waves In Cardiomyocytes From Post-myocardial Infarction Heart Failure Rats Biophysical Journal. 96: 274a-275a. DOI: 10.1016/J.Bpj.2008.12.1359  0.462
2009 Loughrey CM, Smith GL. The Inter-Relationship Between Calcium Transient And Spontaneous Calcium Wave Frequency In Adult Rabbit Ventricular Cardiomyocytes Biophysical Journal. 96: 274a. DOI: 10.1016/J.Bpj.2008.12.1358  0.491
2009 Stølen TO, Høydal MA, Smith GL, Wisløff U. Decreased Arrhythmia Probability After Exercise Training In Post Infarction Heart Failure Biophysical Journal. 96: 22a. DOI: 10.1016/J.Bpj.2008.12.1017  0.376
2008 Fowler MR, Colotti G, Chiancone E, Smith GL, Fearon IM. Sorcin modulates cardiac L-type Ca2+ current by functional interaction with the alpha1C subunit in rabbits. Experimental Physiology. 93: 1233-8. PMID 18603601 DOI: 10.1113/Expphysiol.2008.043497  0.456
2008 Ridley JM, Cheng H, Harrison OJ, Jones SK, Smith GL, Hancox JC, Orchard CH. Spontaneous frequency of rabbit atrioventricular node myocytes depends on SR function. Cell Calcium. 44: 580-91. PMID 18550162 DOI: 10.1016/J.Ceca.2008.04.004  0.499
2008 Myles RC, Burton FL, Cobbe SM, Smith GL. The link between repolarisation alternans and ventricular arrhythmia: does the cellular phenomenon extend to the clinical problem? Journal of Molecular and Cellular Cardiology. 45: 1-10. PMID 18501925 DOI: 10.1016/J.Yjmcc.2008.03.024  0.358
2008 Smith G, MacQuaide N. Cytoplasmic versus intra-SR: the battle of the Ca2+ diffusion coefficients in cardiac muscle. Biophysical Journal. 95: 1005-6. PMID 18469088 DOI: 10.1529/Biophysj.108.133926  0.487
2008 Bye A, Sørhaug S, Ceci M, Høydal MA, Stølen T, Heinrich G, Tjønna AE, Najjar SM, Nilsen OG, Catalucci D, Grimaldi S, Contu R, Steinshamn S, Condorelli G, Smith GL, et al. Carbon monoxide levels experienced by heavy smokers impair aerobic capacity and cardiac contractility and induce pathological hypertrophy. Inhalation Toxicology. 20: 635-46. PMID 18464052 DOI: 10.1080/08958370701883821  0.436
2008 Kemi OJ, Ceci M, Condorelli G, Smith GL, Wisloff U. Myocardial sarcoplasmic reticulum Ca2+ ATPase function is increased by aerobic interval training. European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. 15: 145-8. PMID 18391639 DOI: 10.1097/Hjr.0B013E3282Efd4E0  0.373
2008 Kemi OJ, Ellingsen O, Smith GL, Wisloff U. Exercise-induced changes in calcium handling in left ventricular cardiomyocytes. Frontiers in Bioscience : a Journal and Virtual Library. 13: 356-68. PMID 17981553 DOI: 10.2741/2685  0.322
2007 Seidler T, Loughrey CM, Zibrova D, Kettlewell S, Teucher N, Kögler H, Hasenfuss G, Smith GL. Overexpression of FK-506 binding protein 12.0 modulates excitation contraction coupling in adult rabbit ventricular cardiomyocytes. Circulation Research. 101: 1020-9. PMID 17872463 DOI: 10.1161/Circresaha.107.154609  0.513
2007 Kemi OJ, Ellingsen O, Ceci M, Grimaldi S, Smith GL, Condorelli G, Wisløff U. Aerobic interval training enhances cardiomyocyte contractility and Ca2+ cycling by phosphorylation of CaMKII and Thr-17 of phospholamban. Journal of Molecular and Cellular Cardiology. 43: 354-61. PMID 17689560 DOI: 10.1016/J.Yjmcc.2007.06.013  0.335
2007 Loughrey CM, Otani N, Seidler T, Craig MA, Matsuda R, Kaneko N, Smith GL. K201 modulates excitation-contraction coupling and spontaneous Ca2+ release in normal adult rabbit ventricular cardiomyocytes Cardiovascular Research. 76: 236-246. PMID 17644079 DOI: 10.1016/J.Cardiores.2007.06.014  0.463
2007 MacQuaide N, Dempster J, Smith GL. Measurement and modeling of Ca2+ waves in isolated rabbit ventricular cardiomyocytes. Biophysical Journal. 93: 2581-95. PMID 17545234 DOI: 10.1529/Biophysj.106.102293  0.482
2007 Klauke N, Smith G, Cooper JM. Microfluidic systems to examine intercellular coupling of pairs of cardiac myocytes Lab On a Chip - Miniaturisation For Chemistry and Biology. 7: 731-739. PMID 17538715 DOI: 10.1039/B706175G  0.404
2007 Inya-Agha O, Klauke N, Davies T, Smith G, Cooper JM. Spectroscopic Probing of Dynamic Changes during Stimulation and Cell Remodeling in the Single Cardiac Myocyte Analytical Chemistry. 79: 4581-4587. PMID 17511420 DOI: 10.1021/Ac0622476  0.303
2007 Høydal MA, Wisløff U, Kemi OJ, Britton SL, Koch LG, Smith GL, Ellingsen Ø. Nitric oxide synthase type-1 modulates cardiomyocyte contractility and calcium handling: association with low intrinsic aerobic capacity. European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. 14: 319-25. PMID 17446814 DOI: 10.1097/Hjr.0B013E3280128Bef  0.339
2007 Klauke N, Smith GL, Cooper JM. Microfluidic partitioning of the extracellular space around single cardiac myocytes. Analytical Chemistry. 79: 1205-12. PMID 17263355 DOI: 10.1021/Ac061547K  0.311
2007 Kemi OJ, Arbo I, Høydal MA, Loennechen JP, Wisløff U, Smith GL, Ellingsen Ø. Reduced pH and contractility in failing rat cardiomyocytes. Acta Physiologica (Oxford, England). 188: 185-93. PMID 17054658 DOI: 10.1111/J.1748-1716.2006.01621.X  0.318
2007 Völkers M, Loughrey CM, Macquaide N, Remppis A, DeGeorge BR, Wegner FV, Friedrich O, Fink RH, Koch WJ, Smith GL, Most P. S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes. Cell Calcium. 41: 135-43. PMID 16919727 DOI: 10.1016/J.Ceca.2006.06.001  0.499
2007 Smith G. Matters of the heart: the physiology of cardiac function and failure Experimental Physiology. 92: 973-986. DOI: 10.1113/Expphysiol.2006.034314  0.371
2006 Cheng W, Klauke N, Sedgwick H, Smith GL, Cooper JM. Metabolic monitoring of the electrically stimulated single heart cell within a microfluidic platform. Lab On a Chip. 6: 1424-31. PMID 17066165 DOI: 10.1039/B608202E  0.379
2006 Colotti G, Zamparelli C, Verzili D, Mella M, Loughrey CM, Smith GL, Chiancone E. The W105G and W99G sorcin mutants demonstrate the role of the D helix in the Ca(2+)-dependent interaction with annexin VII and the cardiac ryanodine receptor. Biochemistry. 45: 12519-29. PMID 17029407 DOI: 10.1021/Bi060416A  0.413
2006 Smith G, MacQuaide N. Swallowing a spider to catch a fly: Ca-calmodulin dynamics in adult cardiomyocytes. Journal of Molecular and Cellular Cardiology. 41: 416-417. PMID 16870208 DOI: 10.1016/J.Yjmcc.2006.06.008  0.412
2006 Klauke N, Smith GL, Cooper J. Extracellular recordings of field potentials from single cardiomyocytes. Biophysical Journal. 91: 2543-51. PMID 16844752 DOI: 10.1529/Biophysj.106.085183  0.347
2006 Smith GL, Elliott EE, Kettlewell S, Currie S, Quinn FR. Na(+)/Ca(2+) exchanger expression and function in a rabbit model of myocardial infarction. Journal of Cardiovascular Electrophysiology. 17: S57-S63. PMID 16686683 DOI: 10.1111/J.1540-8167.2006.00384.X  0.477
2005 Kettlewell S, Most P, Currie S, Koch WJ, Smith GL. S100A1 increases the gain of excitation-contraction coupling in isolated rabbit ventricular cardiomyocytes. Journal of Molecular and Cellular Cardiology. 39: 900-10. PMID 16236309 DOI: 10.1016/J.Yjmcc.2005.06.018  0.514
2005 Kohl P, Camelliti P, Burton FL, Smith GL. Electrical coupling of fibroblasts and myocytes: relevance for cardiac propagation. Journal of Electrocardiology. 38: 45-50. PMID 16226073 DOI: 10.1016/J.Jelectrocard.2005.06.096  0.336
2005 Currie S, Quinn FR, Sayeed RA, Duncan AM, Kettlewell S, Smith GL. Selective down-regulation of sub-endocardial ryanodine receptor expression in a rabbit model of left ventricular dysfunction. Journal of Molecular and Cellular Cardiology. 39: 309-17. PMID 15921690 DOI: 10.1016/J.Yjmcc.2005.04.005  0.431
2005 Klauke N, Smith GL, Cooper JM. Stimulation of isolated ventricular myocytes within an open architecture microarray. Ieee Transactions On Bio-Medical Engineering. 52: 531-8. PMID 15759583 DOI: 10.1109/Tbme.2004.842971  0.348
2004 Teucher N, Prestle J, Seidler T, Currie S, Elliott EB, Reynolds DF, Schott P, Wagner S, Kogler H, Inesi G, Bers DM, Hasenfuss G, Smith GL. Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening. Circulation. 110: 3553-9. PMID 15505097 DOI: 10.1161/01.Cir.0000145161.48545.B3  0.486
2004 Kettlewell S, Walker NL, Cobbe SM, Burton FL, Smith GL. The electrophysiological and mechanical effects of 2,3-butane-dione monoxime and cytochalasin-D in the Langendorff perfused rabbit heart. Experimental Physiology. 89: 163-72. PMID 15123545 DOI: 10.1113/Expphysiol.2003.026732  0.341
2004 Loughrey CM, Smith GL, MacEachern KE. Comparison of Ca2+ release and uptake characteristics of the sarcoplasmic reticulum in isolated horse and rabbit cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1149-59. PMID 15117716 DOI: 10.1152/Ajpheart.00060.2004  0.495
2004 Wokosin DL, Loughrey CM, Smith GL. Characterization of a range of fura dyes with two-photon excitation. Biophysical Journal. 86: 1726-38. PMID 14990500 DOI: 10.1016/S0006-3495(04)74241-1  0.397
2004 Loughrey CM, Seidler T, Miller SL, Prestle J, MacEachern KE, Reynolds DF, Hasenfuss G, Smith GL. Over-expression of FK506-binding protein FKBP12.6 alters excitation-contraction coupling in adult rabbit cardiomyocytes. The Journal of Physiology. 556: 919-34. PMID 14966299 DOI: 10.1113/Jphysiol.2003.057166  0.469
2004 Currie S, Loughrey CM, Craig MA, Smith GL. Calcium/calmodulin-dependent protein kinase IIdelta associates with the ryanodine receptor complex and regulates channel function in rabbit heart. The Biochemical Journal. 377: 357-66. PMID 14556649 DOI: 10.1042/Bj20031043  0.484
2004 Loughrey CM, MacEachern KE, Cooper J, Smith GL. Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics. Cell Calcium. 34: 1-9. PMID 12767887 DOI: 10.1016/S0143-4160(03)00012-5  0.472
2003 McConnell G, Smith GL, Girkin JM, Gurney AM, Ferguson AI. Two-photon microscopy of fura-2-loaded cardiac myocytes with an all-solid-state tunable and visible femtosecond laser source. Optics Letters. 28: 1742-4. PMID 14514086 DOI: 10.1364/Ol.28.001742  0.303
2003 Quinn FR, Currie S, Duncan AM, Miller S, Sayeed R, Cobbe SM, Smith GL. Myocardial infarction causes increased expression but decreased activity of the myocardial Na+-Ca2+ exchanger in the rabbit. The Journal of Physiology. 553: 229-42. PMID 12949221 DOI: 10.1113/Jphysiol.2003.050716  0.485
2003 Klauke N, Smith GL, Cooper J. Stimulation of single isolated adult ventricular myocytes within a low volume using a planar microelectrode array. Biophysical Journal. 85: 1766-74. PMID 12944291 DOI: 10.1016/S0006-3495(03)74606-2  0.428
2003 Seidler T, Miller SL, Loughrey CM, Kania A, Burow A, Kettlewell S, Teucher N, Wagner S, Kögler H, Meyers MB, Hasenfuss G, Smith GL. Effects of adenovirus-mediated sorcin overexpression on excitation-contraction coupling in isolated rabbit cardiomyocytes. Circulation Research. 93: 132-9. PMID 12805242 DOI: 10.1161/01.Res.0000081596.90205.E2  0.485
2003 Most P, Remppis A, Weber C, Bernotat J, Ehlermann P, Pleger ST, Kirsch W, Weber M, Uttenweiler D, Smith GL, Katus HA, Fink RH. The C terminus (amino acids 75-94) and the linker region (amino acids 42-54) of the Ca2+-binding protein S100A1 differentially enhance sarcoplasmic Ca2+ release in murine skinned skeletal muscle fibers. The Journal of Biological Chemistry. 278: 26356-64. PMID 12721284 DOI: 10.1074/Jbc.M303338200  0.479
2003 Prestle J, Quinn FR, Smith GL. Ca2+-handling proteins and heart failure: Novel molecular targets? Current Medicinal Chemistry. 10: 967-981. PMID 12678683 DOI: 10.2174/0929867033457656  0.514
2003 Pall GS, Johnson KJ, Smith GL. Abnormal contractile activity and calcium cycling in cardiac myocytes isolated from DMPK knockout mice. Physiological Genomics. 13: 139-46. PMID 12595579 DOI: 10.1152/Physiolgenomics.00107.2002  0.309
2003 Loughrey CM, MacEachern KE, Neary P, Smith GL. The relationship between intracellular [Ca(2+)] and Ca(2+) wave characteristics in permeabilised cardiomyocytes from the rabbit. The Journal of Physiology. 543: 859-70. PMID 12231644 DOI: 10.1113/Jphysiol.2002.021519  0.476
2002 Remppis A, Most P, Löffler E, Ehlermann P, Bernotat J, Pleger S, Börries M, Reppel M, Fischer J, Koch WJ, Smith G, Katus HA. The small EF-hand Ca2+ binding protein S100A1 increases contractility and Ca2+ cycling in rat cardiac myocytes. Basic Research in Cardiology. I56-62. PMID 12479236 DOI: 10.1007/S003950200031  0.527
2002 Ng GA, Hicks MN, Cobbe SM, Smith GL. Depressed inotropic response to increased preload in rabbit hearts with left-ventricular dysfunction induced by chronic myocardial infarction. PflüGers Archiv : European Journal of Physiology. 444: 513-22. PMID 12136271 DOI: 10.1007/S00424-002-0848-3  0.336
2002 Neary P, Duncan AM, Cobbe SM, Smith GL. Assessment of sarcoplasmic reticulum Ca(2+) flux pathways in cardiomyocytes from rabbits with infarct-induced left-ventricular dysfunction. PflüGers Archiv : European Journal of Physiology. 444: 360-71. PMID 12111244 DOI: 10.1007/S00424-002-0794-0  0.506
2002 Wisløff U, Loennechen JP, Currie S, Smith GL, Ellingsen Ø. Aerobic exercise reduces cardiomyocyte hypertrophy and increases contractility, Ca2+ sensitivity and SERCA-2 in rat after myocardial infarction. Cardiovascular Research. 54: 162-74. PMID 12062372 DOI: 10.1016/S0008-6363(01)00565-X  0.468
2002 Ugwu AC, Smith GL, Miller DJ, McGrath J. Calcium-sensitivity of smooth muscle contraction in the isolated perfused rat tail artery African Journal of Biomedical Research. 5. DOI: 10.4314/Ajbr.V5I1-2.53968  0.611
2002 Quinn FR, Cobbe SM, Smith GL. Alterations in Single-Cell Calcium Handling Could Contribute to Diastolic Dysfunction and Arrhythmogenesis in Heart Failure Clinical Science. 103: 8P-9P. DOI: 10.1042/Cs103008Pb  0.304
2001 Most P, Bernotat J, Ehlermann P, Pleger ST, Reppel M, Börries M, Niroomand F, Pieske B, Janssen PML, Eschenhagen T, Karczewski P, Smith GL, Koch WJ, Katus HA, Remppis A. S100A1: A regulator of myocardial contractility Proceedings of the National Academy of Sciences of the United States of America. 98: 13889-13894. PMID 11717446 DOI: 10.1073/Pnas.241393598  0.515
2001 Smith GL, O'Neill SC. A comparison of the effects of ATP and tetracaine on spontaneous Ca(2+) release from rat permeabilised cardiac myocytes. The Journal of Physiology. 534: 37-47. PMID 11432990 DOI: 10.1111/j.1469-7793.2001.00037.x  0.366
2001 Wisløff U, Loennechen JP, Falck G, Beisvag V, Currie S, Smith G, Ellingsen Ø. Increased contractility and calcium sensitivity in cardiac myocytes isolated from endurance trained rats. Cardiovascular Research. 50: 495-508. PMID 11376625 DOI: 10.1016/S0008-6363(01)00210-3  0.501
2001 Prestle J, Janssen PM, Janssen AP, Zeitz O, Lehnart SE, Bruce L, Smith GL, Hasenfuss G. Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca(2+) leak from the sarcoplasmic reticulum and increases contractility. Circulation Research. 88: 188-94. PMID 11157671 DOI: 10.1161/01.Res.88.2.188  0.473
2000 Smith GL, Duncan AM, Neary P, Bruce L, Burton FL. P(i) inhibits the SR Ca(2+) pump and stimulates pump-mediated Ca(2+) leak in rabbit cardiac myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 279: H577-85. PMID 10924056 DOI: 10.1152/Ajpheart.2000.279.2.H577  0.494
2000 McIntosh MA, Cobbe SM, Smith GL. Heterogeneous changes in action potential and intracellular Ca2+ in left ventricular myocyte sub-types from rabbits with heart failure Cardiovascular Research. 45: 397-409. PMID 10728360 DOI: 10.1016/S0008-6363(99)00360-0  0.425
2000 Neary P, Cobbe SM, Smith GL. Reduced sarcoplasmic reticulum Ca2+ release in rabbits with left ventricular dysfunction. Annals of the New York Academy of Sciences. 853: 338-40. PMID 10603974 DOI: 10.1111/J.1749-6632.1998.Tb08294.X  0.458
1999 Currie S, Smith GL. Enhanced phosphorylation of phospholamban and downregulation of sarco/endoplasmic reticulum Ca2+ ATpase type 2 (SERCA 2) in cardiac sarcoplasmic reticulum from rabbits with heart failure Cardiovascular Research. 41: 135-146. PMID 10325961 DOI: 10.1016/S0008-6363(98)00241-7  0.395
1998 Smith GL, Steele DS. Measurement of SR Ca2+ content in the presence of caffeine in permeabilised rat cardiac trabeculae. PflüGers Archiv : European Journal of Physiology. 437: 139-48. PMID 9817798 DOI: 10.1007/S004240050758  0.718
1998 Smith GL, Austin C, Crichton C, Wray S. A review of the actions and control of intracellular pH in vascular smooth muscle. Cardiovascular Research. 38: 316-31. PMID 9709392 DOI: 10.1016/S0008-6363(98)00020-0  0.734
1998 Ng GA, Cobbe SM, Smith GL. Non-uniform prolongation of intracellular Ca2+ transients recorded from the epicardial surface of isolated hearts from rabbits with heart failure. Cardiovascular Research. 37: 489-502. PMID 9614503 DOI: 10.1016/S0008-6363(97)00255-1  0.414
1998 Burdyga TV, Taggart MJ, Crichton C, Smith GL, Wray S. The mechanism of Ca2+ release from the SR of permeabilised guinea-pig and rat ureteric smooth muscle. Biochimica Et Biophysica Acta. 1402: 109-14. PMID 9551092 DOI: 10.1016/S0167-4889(97)00149-3  0.798
1998 Orchard CH, Smith GL, Steele DS. Effects of cytosolic Ca2+ on the Ca2+ content of the sarcoplasmic reticulum in saponin-permeabilized rat ventricular trabeculae. PflüGers Archiv : European Journal of Physiology. 435: 555-63. PMID 9446704 DOI: 10.1007/S004240050552  0.713
1997 Burton FL, Smith GL. The effect of cromakalim on intracellular [Ca2+] in isolated rat skeletal muscle during fatigue and metabolic blockade. Experimental Physiology. 82: 469-83. PMID 9179567 DOI: 10.1113/Expphysiol.1997.Sp004040  0.412
1997 Crichton CA, Smith GC, Smith GL. alpha-Toxin-permeabilised rabbit fetal ductus arteriosus is more sensitive to Ca2+ than aorta or main pulmonary artery. Cardiovascular Research. 33: 223-9. PMID 9059548 DOI: 10.1016/S0008-6363(96)00171-X  0.798
1997 McCarron JG, Crichton CA, Langton PD, MacKenzie A, Smith GL. Myogenic contraction by modulation of voltage-dependent calcium currents in isolated rat cerebral arteries. The Journal of Physiology. 498: 371-9. PMID 9032685 DOI: 10.1113/jphysiol.1997.sp021864  0.786
1994 Wilson SM, Whiteford ML, Bovell DL, Pediani JD, Ko WH, Smith GL, Lee CM, Elder HY. The regulation of membrane 125I- and 86Rb+ permeability in a virally transformed cell line (NCL-SG3) derived from the human sweat gland epithelium. Experimental Physiology. 79: 445-59. PMID 8074857 DOI: 10.1113/Expphysiol.1994.Sp003779  0.358
1994 Crichton CA, Templeton AG, Smith GL. Effect of altered bathing pH on calcium activated force in alpha toxin permeabilised rat portal vein and human umbilical artery. Cardiovascular Research. 28: 1378-84. PMID 7954649 DOI: 10.1093/Cvr/28.9.1378  0.759
1994 MacFarlane NG, Miller DJ, Smith GL, Steele DS. Effects of oxidants on the sarcoplasmic reticulum of saponin treated rat ventricular trabeculae. Cardiovascular Research. 28: 1647-52. PMID 7842458 DOI: 10.1093/Cvr/28.11.1647  0.766
1993 Smith GL, Crichton CA. Ca-EGTA affects the relationship between [Ca2+] and tension in alpha-toxin permeabilized rat anococcygeus smooth muscle. Journal of Muscle Research and Cell Motility. 14: 76-84. PMID 8478431 DOI: 10.1007/Bf00132182  0.803
1993 Crichton CA, Templeton AG, McGrath JC, Smith GL. Thromboxane A2 analogue, U-46619, potentiates calcium-activated force in human umbilical artery. The American Journal of Physiology. 264: H1878-83. PMID 8322917 DOI: 10.1152/Ajpheart.1993.264.6.H1878  0.782
1993 Steele DS, Smith GL. Effects of 2,3-butanedione monoxime on sarcoplasmic reticulum of saponin-treated rat cardiac muscle. The American Journal of Physiology. 265: H1493-500. PMID 8238560 DOI: 10.1152/Ajpheart.1993.265.5.H1493  0.724
1993 Crichton CA, Taggart MJ, Wray S, Smith GL. Effects of pH and inorganic phosphate on force production in alpha-toxin-permeabilized isolated rat uterine smooth muscle. The Journal of Physiology. 465: 629-45. PMID 8229854 DOI: 10.1113/Jphysiol.1993.Sp019697  0.801
1993 Smith GL, Donoso P, Bauer CJ, Eisner DA. Relationship between intracellular pH and metabolite concentrations during metabolic inhibition in isolated ferret heart. The Journal of Physiology. 472: 11-22. PMID 8145137 DOI: 10.1113/Jphysiol.1993.Sp019932  0.304
1993 Eisner DA, Smith GL, O'Neill SC. The effects of lactic acid production on contraction and intracellular pH during hypoxia in cardiac muscle. Basic Research in Cardiology. 88: 421-9. PMID 8117248 DOI: 10.1007/Bf00795409  0.358
1992 Steele DS, Smith GL. The effects of caffeine and Ca2+ on rigor tension in triton-treated rat ventricular trabeculae. PflüGers Archiv : European Journal of Physiology. 421: 343-9. PMID 1408658 DOI: 10.1007/Bf00374222  0.708
1990 Steele DS, Smith GL, Miller DJ. The effects of taurine on Ca2+ uptake by the sarcoplasmic reticulum and Ca2+ sensitivity of chemically skinned rat heart. The Journal of Physiology. 422: 499-511. PMID 2352190 DOI: 10.1113/Jphysiol.1990.Sp017997  0.73
1990 Crichton CA, Smith GL, Miller DJ, McGrath JC. The effect of ATP on the response of intact and toxin-permeabilized isolated rat anococcygeus muscle to noradrenaline and acetylcholine Journal of Molecular and Cellular Cardiology. 22: S1. DOI: 10.1016/0022-2828(90)91530-K  0.755
1989 O'Neill SC, Valdeolmillos M, Smith GL, Eisner DA. The effects of metabolic inhibition on intracellular pH and Ca. Molecular and Cellular Biochemistry. 89: 199-203. PMID 2811865 DOI: 10.1007/Bf00220776  0.498
1989 Allen DG, Lee JA, Smith GL. The consequences of simulated ischaemia on intracellular Ca2+ and tension in isolated ferret ventricular muscle. The Journal of Physiology. 410: 297-323. PMID 2795481 DOI: 10.1113/jphysiol.1989.sp017534  0.316
1989 Valdeolmillos M, O'Neill SC, Smith GL, Eisner DA. Calcium-induced calcium release activates contraction in intact cardiac cells. Pflã¼Gers Archiv : European Journal of Physiology. 413: 676-8. PMID 2726431 DOI: 10.1007/Bf00581820  0.338
1989 Eisner DA, Nichols CG, O'Neill SC, Smith GL, Valdeolmillos M. The effects of metabolic inhibition on intracellular calcium and pH in isolated rat ventricular cells. The Journal of Physiology. 411: 393-418. PMID 2614727 DOI: 10.1113/Jphysiol.1989.Sp017580  0.427
1989 Lederer WJ, Nichols CG, Smith GL. The mechanism of early contractile failure of isolated rat ventricular myocytes subjected to complete metabolic inhibition. The Journal of Physiology. 413: 329-49. PMID 2600854 DOI: 10.1113/Jphysiol.1989.Sp017657  0.301
1989 Crichton CA, Smith GL, Miller DJ, McGrath JC. The modulation of force in isolated rat EGTA-treated anococcygeus muscle by phosphate, cyclic AMP and noradrenaline. Quarterly Journal of Experimental Physiology (Cambridge, England). 74: 943-5. PMID 2556730 DOI: 10.1113/Expphysiol.1989.Sp003365  0.792
1988 Smith GL, Allen DG. Effects of metabolic blockade on intracellular calcium concentration in isolated ferret ventricular muscle Circulation Research. 62: 1223-1236. PMID 3383366 DOI: 10.1161/01.RES.62.6.1223  0.384
1988 Allen DG, Nichols CG, Smith GL. The effects of changes in muscle length during diastole on the calcium transient in ferret ventricular muscle. The Journal of Physiology. 406: 359-70. PMID 3254417 DOI: 10.1113/jphysiol.1988.sp017385  0.41
1988 Smith GL, Valdeolmillos M, Eisner DA, Allen DG. Effects of rapid application of caffeine on intracellular calcium concentration in ferret papillary muscles. The Journal of General Physiology. 92: 351-68. PMID 3225553 DOI: 10.1085/Jgp.92.3.351  0.414
1987 Allen DG, Smith GL. The effects of hypertonicity on tension and intracellular calcium concentration in ferret ventricular muscle Journal of Physiology. 425-439. PMID 3116206 DOI: 10.1113/jphysiol.1987.sp016418  0.423
1986 Allen DG, Eisner DA, Morris PG, Pirolo JS, Smith GL. Metabolic consequences of increasing intracellular calcium and force production in perfused ferret hearts. The Journal of Physiology. 376: 121-41. PMID 3795073 DOI: 10.1113/Jphysiol.1986.Sp016145  0.378
1985 Allen DG, Eisner DA, Pirolo JS, Smith GL. The relationship between intracellular calcium and contraction in calcium-overloaded ferret papillary muscles. The Journal of Physiology. 364: 169-82. PMID 4032294 DOI: 10.1113/Jphysiol.1985.Sp015737  0.478
1985 Miller DJ, Smith GL. The contractile behaviour of EGTA- and detergent-treated heart muscle. Journal of Muscle Research and Cell Motility. 6: 541-67. PMID 3934211 DOI: 10.1007/Bf00711914  0.566
1985 Miller DJ, Elder HY, Smith GL. Ultrastructural and X-ray microanalytical studies of EGTA- and detergent-treated heart muscle. Journal of Muscle Research and Cell Motility. 6: 525-40. PMID 3934210 DOI: 10.1007/Bf00711913  0.445
1985 Smith GL, Miller DJ. Potentiometric measurements of stoichiometric and apparent affinity constants of EGTA for protons and divalent ions including calcium. Biochimica Et Biophysica Acta. 839: 287-99. PMID 2985122 DOI: 10.1016/0304-4165(85)90011-X  0.502
1984 Miller DJ, Smith GL. EGTA purity and the buffering of calcium ions in physiological solutions. The American Journal of Physiology. 246: C160-6. PMID 6421170  0.492
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