| Year |
Citation |
Score |
| 2024 |
Barry ME, Rynkiewicz MJ, Pavadai E, Viana A, Lehman W, Moore JR. Glutamate 139 of tropomyosin is critical for cardiac thin filament blocked-state stabilization. Journal of Molecular and Cellular Cardiology. PMID 38266978 DOI: 10.1016/j.yjmcc.2024.01.004 |
0.653 |
|
| 2023 |
Lehman W, Rynkiewicz MJ. Troponin-I-induced tropomyosin pivoting defines thin-filament function in relaxed and active muscle. The Journal of General Physiology. 155. PMID 37249525 DOI: 10.1085/jgp.202313387 |
0.622 |
|
| 2023 |
Halder SS, Rynkiewicz MJ, Creso JG, Sewanan LR, Howland L, Moore JR, Lehman W, Campbell SG. Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TPM1 variant S215L. Pnas Nexus. 2: pgad011. PMID 36896133 DOI: 10.1093/pnasnexus/pgad011 |
0.6 |
|
| 2023 |
Doran MH, Rynkiewicz MJ, Rassici D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W. Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. The Journal of General Physiology. 155. PMID 36633586 DOI: 10.1085/jgp.202213267 |
0.573 |
|
| 2022 |
Doran MH, Rynkiewicz MJ, Pavadai E, Bodt SML, Rasicci D, Moore JR, Yengo CM, Bullitt E, Lehman W. Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. The Journal of General Physiology. 155. PMID 36459134 DOI: 10.1085/jgp.202213274 |
0.626 |
|
| 2022 |
Rynkiewicz MJ, Pavadai E, Lehman W. Modeling Human Cardiac Thin Filament Structures. Frontiers in Physiology. 13: 932333. PMID 35812320 DOI: 10.3389/fphys.2022.932333 |
0.606 |
|
| 2022 |
Pavadai E, Rynkiewicz MJ, Yang Z, Gould IR, Marston SB, Lehman W. Modulation of cardiac thin filament structure by phosphorylated troponin-I analyzed by protein-protein docking and molecular dynamics simulation. Archives of Biochemistry and Biophysics. 725: 109282. PMID 35577070 DOI: 10.1016/j.abb.2022.109282 |
0.62 |
|
| 2022 |
Teekakirikul P, Zhu W, Xu X, Young CB, Tan T, Smith AM, Wang C, Peterson KA, Gabriel GC, Ho S, Sheng Y, Moreau de Bellaing A, Sonnenberg DA, Lin JH, Fotiou E, ... ... Rynkiewicz MJ, et al. Genetic resiliency associated with dominant lethal mutation causing atrial septal defect with high heritability. Cell Reports. Medicine. 3: 100501. PMID 35243414 DOI: 10.1016/j.xcrm.2021.100501 |
0.551 |
|
| 2021 |
Sewanan LR, Park J, Rynkiewicz MJ, Racca AW, Papoutsidakis N, Schwan J, Jacoby DL, Moore JR, Lehman W, Qyang Y, Campbell SG. Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation. The Journal of General Physiology. 153. PMID 34319370 DOI: 10.1085/jgp.202012640 |
0.585 |
|
| 2021 |
Lehman W, Pavadai E, Rynkiewicz MJ. C-terminal troponin-I residues trap tropomyosin in the muscle thin filament blocked-state. Biochemical and Biophysical Research Communications. 551: 27-32. PMID 33714756 DOI: 10.1016/j.bbrc.2021.03.010 |
0.597 |
|
| 2020 |
Racca AW, Rynkiewicz MJ, LaFave N, Ghosh A, Lehman W, Moore JR. M8R tropomyosin mutation disrupts actin-binding and filament regulation: the beginning affects the middle and end. The Journal of Biological Chemistry. PMID 33020181 DOI: 10.1074/jbc.RA120.014713 |
0.674 |
|
| 2020 |
Doran MH, Pavadai E, Rynkiewicz MJ, Walklate J, Bullitt E, Moore JR, Regnier M, Geeves MA, Lehman W. Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. Biophysical Journal. PMID 32730789 DOI: 10.1016/J.Bpj.2020.07.006 |
0.656 |
|
| 2020 |
Pavadai E, Lehman W, Rynkiewicz MJ. Protein-Protein Docking Reveals Dynamic Interactions of Tropomyosin on Actin Filaments. Biophysical Journal. 119: 75-86. PMID 32521240 DOI: 10.1016/J.Bpj.2020.05.017 |
0.635 |
|
| 2020 |
Viswanathan MC, Schmidt W, Franz P, Rynkiewicz MJ, Newhard CS, Madan A, Lehman W, Swank DM, Preller M, Cammarato A. A role for actin flexibility in thin filament-mediated contractile regulation and myopathy. Nature Communications. 11: 2417. PMID 32415060 DOI: 10.1038/S41467-020-15922-5 |
0.649 |
|
| 2020 |
Pavadai E, Rynkiewicz MJ, Lehman W. A Tropomyosin Cable Model on Thin-Filaments Deduced by Protein-Protein Docking Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3205 |
0.482 |
|
| 2020 |
Rynkiewicz MJ, Lehman W. Molecular Dynamics Simulations of Alpha-Beta-Tropomyosin Show Conformational Properties of Heterodimeric Tropomyosin Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1598 |
0.477 |
|
| 2019 |
Sundar S, Rynkiewicz MJ, Ghosh A, Lehman W, Moore JR. Cardiomyopathy Mutation Alters End-to-End Junction of Tropomyosin and Reduces Calcium Sensitivity. Biophysical Journal. PMID 31882250 DOI: 10.1016/J.Bpj.2019.11.3396 |
0.67 |
|
| 2019 |
Pavadai E, Rynkiewicz MJ, Ghosh A, Lehman W. Docking Troponin T onto the Tropomyosin Overlapping Domain of Thin Filaments. Biophysical Journal. PMID 31864661 DOI: 10.1016/J.Bpj.2019.11.3393 |
0.639 |
|
| 2019 |
Janco M, Rynkiewicz MJ, Li L, Hook J, Eiffe E, Ghosh A, Böcking T, Lehman WJ, Hardeman EC, Gunning PW. Molecular integration of the anti-tropomyosin compound ATM-3507 into the coiled coil overlap region of the cancer-associated Tpm3.1. Scientific Reports. 9: 11262. PMID 31375704 DOI: 10.1038/S41598-019-47592-9 |
0.613 |
|
| 2019 |
Lehman W, Moore JR, Campbell SG, Rynkiewicz MJ. The Effect of Tropomyosin Mutations on Actin-Tropomyosin Binding: In Search of Lost Time. Biophysical Journal. PMID 31130236 DOI: 10.1016/J.Bpj.2019.05.009 |
0.668 |
|
| 2019 |
Lehman W, Rynkiewicz MJ, Moore JR. A new twist on tropomyosin binding to actin filaments: perspectives on thin filament function, assembly and biomechanics. Journal of Muscle Research and Cell Motility. PMID 30771202 DOI: 10.1007/S10974-019-09501-5 |
0.646 |
|
| 2019 |
Racca AW, LaFave N, Jones S, Rynkiewicz MJ, Lehman W, Moore JR. Functional Implications of Dcm End-to-End Bond Mutation in A-Tropomyosin Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.989 |
0.488 |
|
| 2019 |
Rynkiewicz MJ, Moore JR, Campbell SG, Lehman W. A New Twist on the Mechanism of Mutation-Induced Tropomyosin Dysfunction Biophysical Journal. 116: 552a. DOI: 10.1016/J.Bpj.2018.11.2966 |
0.51 |
|
| 2019 |
Sundar S, Rynkiewicz MJ, Lehman W, Moore JR. Cardiomyopathy Mutation at End-End Overlap of Alpha - Tropomyosin Influences Cooperative Activation and Calcium Sensitivity Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2517 |
0.506 |
|
| 2019 |
Kiani FA, Lehman W, Fischer S, Rynkiewicz MJ. Tropomyosin Cable Formation and Its Influence on the Structural Dynamics of Tropomyosin Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.199 |
0.504 |
|
| 2019 |
Ghosh A, Janco M, Böcking T, Gunning PW, Lehman W, Rynkiewicz MJ. Structure of the Tpm3.1 N-Terminus: A New Target for Anti-Cancer Treatment Biophysical Journal. 116: 253a-254a. DOI: 10.1016/J.Bpj.2018.11.1382 |
0.429 |
|
| 2018 |
Kiani FA, Lehman W, Fischer S, Rynkiewicz MJ. Spontaneous transitions of actin-bound tropomyosin toward blocked and closed states. The Journal of General Physiology. PMID 30442774 DOI: 10.1085/Jgp.201812188 |
0.618 |
|
| 2018 |
Lehman W, Li X, Kiani FA, Moore JR, Campbell SG, Fischer S, Rynkiewicz MJ. Precise Binding of Tropomyosin on Actin Involves Sequence-Dependent Variance in Coiled-Coil Twisting. Biophysical Journal. PMID 30195938 DOI: 10.1016/J.Bpj.2018.08.017 |
0.623 |
|
| 2018 |
Farman GP, Rynkiewicz MJ, Orzechowski M, Lehman W, Moore JR. HCM and DCM cardiomyopathy-linked α-tropomyosin mutations influence off-state stability and crossbridge interaction on thin filaments. Archives of Biochemistry and Biophysics. PMID 29626422 DOI: 10.1016/J.Abb.2018.04.002 |
0.645 |
|
| 2018 |
Kiani FA, Rynkiewicz MJ, Fischer S, Lehman W. Tropomyosin Translocation on F-Actin Revealed by Molecular Dynamics Simulations Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.769 |
0.56 |
|
| 2018 |
Sewanan LR, Park J, Rynkiewicz MJ, Hollenberg SM, Papoutsidakis N, Jacoby DL, Moore JR, Lehman W, Qyang Y, Campbell SG. Pathogenic Mechanisms of the Cardiomyopathy-Associated Alpha-Tropomyosin Variant E192K as Revealed by Multiscale Modeling and Experiments Biophysical Journal. 114: 495a. DOI: 10.1016/J.Bpj.2017.11.2714 |
0.478 |
|
| 2018 |
Viswanathan MC, Schmidt W, Madan A, Sullivan LC, Newhard CS, Rynkiewicz MJ, Lehman W, Swank DM, Cammarato A. The ACTC M305L Hypertrophic Cardiomyopathy Mutation Results in Hypercontractility and Impaired Relaxation of Drosophila Muscles Biophysical Journal. 114: 315a. DOI: 10.1016/J.Bpj.2017.11.1776 |
0.522 |
|
| 2017 |
Rynkiewicz MJ, Prum T, Hollenberg S, Kiani FA, Fagnant PM, Marston SB, Trybus KM, Fischer S, Moore JR, Lehman W. Tropomyosin Must Interact Weakly with Actin to Effectively Regulate Thin Filament Function. Biophysical Journal. 113: 2444-2451. PMID 29211998 DOI: 10.1016/J.Bpj.2017.10.004 |
0.666 |
|
| 2017 |
Viswanathan MC, Schmidt W, Rynkiewicz MJ, Agarwal K, Gao J, Katz J, Lehman W, Cammarato A. Distortion of the Actin A-Triad Results in Contractile Disinhibition and Cardiomyopathy. Cell Reports. 20: 2612-2625. PMID 28903042 DOI: 10.1016/J.Celrep.2017.08.070 |
0.643 |
|
| 2017 |
Rynkiewicz M, Stehn J, Gunning P, Lehman W. Structure of the Anti-Cancer Compound TR100 Target-Sites on Tpm3.1 Tropomyosin Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.3019 |
0.483 |
|
| 2017 |
Sewanan LR, Park J, Ren Y, Urdaneta A, Rynkiewicz M, Moore J, Lehman W, Jacoby DL, Qyang Y, Campbell SG. Investigating the Phenotype of Cardiomyopathy-Associated Alpha-Tropomyosin E192K Mutation in Patient-Derived Engineered Heart Tissue Biophysical Journal. 112: 260a. DOI: 10.1016/J.Bpj.2016.11.1412 |
0.531 |
|
| 2016 |
Rynkiewicz MJ, Fischer S, Lehman W. The propensity for tropomyosin twisting in the presence and absence of F-actin. Archives of Biochemistry and Biophysics. PMID 27663225 DOI: 10.1016/J.Abb.2016.09.008 |
0.641 |
|
| 2016 |
Fischer S, Rynkiewicz MJ, Moore JR, Lehman W. Tropomyosin diffusion over actin subunits facilitates thin filament assembly. Structural Dynamics (Melville, N.Y.). 3: 012002. PMID 26798831 DOI: 10.1063/1.4940223 |
0.634 |
|
| 2016 |
Fischer S, Rynkiewicz MJ, Moore JR, Lehman W. Tropomyosin diffusion over actin subunits facilitates thin filament assembly Structural Dynamics. 3. DOI: 10.1063/1.4940223 |
0.553 |
|
| 2016 |
Farman GP, Rynkiewicz M, Orzechowski M, Lehman W, Moore J. Cardiomyopathy Linked Mutations in Alpha Tropomyosin Influence Blocked State Stability but not Myosin Strong Binding Biophysical Journal. 110: 124a-125a. DOI: 10.1016/J.Bpj.2015.11.718 |
0.694 |
|
| 2016 |
Rynkiewicz M, Schott V, Orzechowski M, Fischer S, Lehman W. Does Tropomyosin Slide or Roll over F-Actin during Regulatory Transitions? Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2805 |
0.645 |
|
| 2015 |
Rynkiewicz MJ, Schott V, Orzechowski M, Lehman W, Fischer S. Electrostatic interaction map reveals a new binding position for tropomyosin on F-actin. Journal of Muscle Research and Cell Motility. 36: 525-33. PMID 26286845 DOI: 10.1007/S10974-015-9419-Z |
0.618 |
|
| 2010 |
Hartshorn KL, White MR, Rynkiewicz M, Sorensen G, Holmskov U, Head J, Crouch EC. Monoclonal antibody-assisted structure-function analysis of the carbohydrate recognition domain of surfactant protein D. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L384-92. PMID 20601494 DOI: 10.1152/Ajplung.00096.2010 |
0.341 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2015 |
Tripathi S, Wang G, White M, Rynkiewicz M, Seaton B, Hartshorn K. Identifying the Critical Domain of LL-37 Involved in Mediating Neutrophil Activation in the Presence of Influenza Virus: Functional and Structural Analysis. Plos One. 10: e0133454. PMID 26308522 DOI: 10.1371/Journal.Pone.0133454 |
0.287 |
|
| 2016 |
Goh BC, Wu H, Rynkiewicz MJ, Schulten K, Seaton BA, McCormack FX. Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations. Biochemistry. PMID 27324153 DOI: 10.1021/Acs.Biochem.6B00048 |
0.221 |
|
| 2021 |
Lehman W, Rynkiewicz MJ. An Atomic Model of the Thin Filament Describing Troponin-I -Tropomyosin Binding at Low-Calcium Biophysical Journal. 120: 251a. DOI: 10.1016/J.BPJ.2020.11.1630 |
0.213 |
|
| 2005 |
Vedula LS, Rynkiewicz MJ, Pyun HJ, Coates RM, Cane DE, Christianson DW. Molecular recognition of the substrate diphosphate group governs product diversity in trichodiene synthase mutants. Biochemistry. 44: 6153-63. PMID 15835903 DOI: 10.1021/Bi050059O |
0.213 |
|
| 2013 |
Goh BC, Rynkiewicz MJ, Cafarella TR, White MR, Hartshorn KL, Allen K, Crouch EC, Calin O, Seeberger PH, Schulten K, Seaton BA. Molecular mechanisms of inhibition of influenza by surfactant protein D revealed by large-scale molecular dynamics simulation. Biochemistry. 52: 8527-38. PMID 24224757 DOI: 10.1021/Bi4010683 |
0.207 |
|
| 2011 |
Shang F, Rynkiewicz MJ, McCormack FX, Wu H, Cafarella TM, Head JF, Seaton BA. Crystallographic complexes of surfactant protein A and carbohydrates reveal ligand-induced conformational change. The Journal of Biological Chemistry. 286: 757-65. PMID 21047777 DOI: 10.1074/Jbc.M110.175265 |
0.207 |
|
| 2023 |
Lewkowicz E, Nakamura MN, Rynkiewicz MJ, Gursky O. Molecular modeling of apoE in complexes with Alzheimer's amyloid-β fibrils from human brain suggests a structural basis for apolipoprotein co-deposition with amyloids. Biorxiv : the Preprint Server For Biology. PMID 37577501 DOI: 10.1101/2023.08.04.551703 |
0.206 |
|
| 2018 |
van Eijk M, Rynkiewicz MJ, Khatri K, Leymarie N, Zaia J, White MR, Hartshorn KL, Cafarella TR, Van Die I, Hessing M, Seaton BA, Haagsman HP. Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus. The Journal of Biological Chemistry. PMID 29769321 DOI: 10.1074/Jbc.Ra117.001430 |
0.202 |
|
| 2006 |
Lazarova TI, Jin L, Rynkiewicz M, Gorga JC, Bibbins F, Meyers HV, Babine R, Strickler J. Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa. Bioorganic & Medicinal Chemistry Letters. 16: 5022-7. PMID 16876411 DOI: 10.1016/J.Bmcl.2006.07.043 |
0.194 |
|
| 2023 |
Lewkowicz E, Nakamura MN, Rynkiewicz MJ, Gursky O. Molecular modeling of apoE in complexes with Alzheimer's amyloid-β fibrils from human brain suggests a structural basis for apolipoprotein co-deposition with amyloids. Cellular and Molecular Life Sciences : Cmls. 80: 376. PMID 38010414 DOI: 10.1007/s00018-023-05026-w |
0.188 |
|
| 2013 |
Goh BC, Zou X, Rynkiewicz MJ, Seaton BA, Schulten K. Effect of Two Point Mutations in Lung Surfactant Protein-D on Enhancing its Inhibition Activity Against Influenza a Virus Biophysical Journal. 104: 556a. DOI: 10.1016/J.Bpj.2012.11.3080 |
0.185 |
|
| 2017 |
Rynkiewicz MJ, Wu H, Cafarella TR, Nikolaidis NM, Head JF, Seaton BA, McCormack FX. Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop. Biochemistry. PMID 28719181 DOI: 10.1021/acs.biochem.6b01313 |
0.181 |
|
| 2015 |
Goh BC, Rynkiewicz MJ, McCormack FX, Seaton BA, Schulten K. Unraveling the Dual Role of Surfactant Protein a at Atomistic Detail Biophysical Journal. 108: 255a-256a. DOI: 10.1016/J.Bpj.2014.11.1413 |
0.181 |
|
| 2011 |
Crouch E, Nikolaidis N, McCormack FX, McDonald B, Allen K, Rynkiewicz MJ, Cafarella TM, White M, Lewnard K, Leymarie N, Zaia J, Seaton BA, Hartshorn KL. Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo. The Journal of Biological Chemistry. 286: 40681-92. PMID 21965658 DOI: 10.1074/Jbc.M111.300673 |
0.175 |
|
| 2012 |
van Eijk M, Rynkiewicz MJ, White MR, Hartshorn KL, Zou X, Schulten K, Luo D, Crouch EC, Cafarella TR, Head JF, Haagsman HP, Seaton BA. A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D. The Journal of Biological Chemistry. 287: 26666-77. PMID 22685299 DOI: 10.1074/Jbc.M112.368571 |
0.171 |
|
| 2012 |
Chong Goh B, Zou X, Rynkiewicz MJ, Seaton BA, Schulten KJ. Mechanism of Interaction Between Lung Surfactant Protein-D and Influenza A Virus Hemagglutinin Biophysical Journal. 102: 63a. DOI: 10.1016/J.Bpj.2011.11.373 |
0.169 |
|
| 2014 |
Lu Z, Rynkiewicz MJ, Madico G, Li S, Yang CY, Perkins HM, Sompuram SR, Kodela V, Liu T, Morris T, Wang D, Roche MI, Seaton BA, Sharon J. B-cell epitopes in GroEL of Francisella tularensis. Plos One. 9: e99847. PMID 24968190 DOI: 10.1371/Journal.Pone.0099847 |
0.162 |
|
| 2013 |
Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Wang Q, Costello CE, Zaia J, Seaton BA, Sharon J. The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide. Immunology. 140: 374-89. PMID 23844703 DOI: 10.1111/Imm.12150 |
0.161 |
|
| 2001 |
Rynkiewicz MJ, Cane DE, Christianson DW. Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade Proceedings of the National Academy of Sciences of the United States of America. 98: 13543-13548. PMID 11698643 DOI: 10.1073/Pnas.231313098 |
0.158 |
|
| 2014 |
Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Roche MI, Seaton BA, Sharon J. Functional and structural characterization of Francisella tularensis O-antigen antibodies at the low end of antigen reactivity. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33: 235-45. PMID 25171003 DOI: 10.1089/Mab.2014.0022 |
0.155 |
|
| 2021 |
Halder SS, Sewanan LR, Rynkiewicz MJ, Howland L, Moore JR, Lehman W, Campbell SG. Investigating the Effect of HCM-Associated TPM1 Mutation S215L on Human Engineered Heart Tissues Biophysical Journal. 120: 254a. DOI: 10.1016/J.BPJ.2020.11.1645 |
0.145 |
|
| 2004 |
Jin L, Pluskey S, Petrella EC, Cantin SM, Gorga JC, Rynkiewicz MJ, Pandey P, Strickler JE, Babine RE, Weaver DT, Seidl KJ. The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors. The Journal of Biological Chemistry. 279: 42818-25. PMID 15292186 DOI: 10.1074/Jbc.M407096200 |
0.137 |
|
| 2011 |
Rynkiewicz MJ, Luo D, Leymarie N, Crouch EC, Hartshorn KL, Head JF, McCormack FX, van Eijk M, Zaia J, Seaton BA. Mechanisms of Interaction Between Lung Collectins and Influenza a Virus Hemagglutinin Biophysical Journal. 100: 214a-215a. DOI: 10.1016/J.Bpj.2010.12.1384 |
0.129 |
|
| 2012 |
Rynkiewicz MJ, Lu Z, Hui JH, Sharon J, Seaton BA. Structural analysis of a protective epitope of the Francisella tularensis O-polysaccharide. Biochemistry. 51: 5684-94. PMID 22747335 DOI: 10.1021/Bi201711M |
0.127 |
|
| 2002 |
Rynkiewicz MJ, Cane DE, Christianson DW. X-ray crystal structures of D100E trichodiene synthase and its pyrophosphate complex reveal the basis for terpene product diversity. Biochemistry. 41: 1732-41. PMID 11827517 DOI: 10.1021/Bi011960G |
0.124 |
|
| 1996 |
Rynkiewicz MJ, Seaton BA. Chemical rescue by guanidine derivatives of an arginine-substituted site-directed mutant of Escherichia coli ornithine transcarbamylase Biochemistry. 35: 16174-16179. PMID 8973189 DOI: 10.1021/Bi961311I |
0.122 |
|
| 2024 |
Rynkiewicz MJ, Childers MC, Karpicheva OE, Regnier M, Geeves MA, Lehman W. Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin. The Journal of General Physiology. 156. PMID 38607351 DOI: 10.1085/jgp.202413538 |
0.12 |
|
| 2000 |
Caruthers JM, Kang I, Rynkiewicz MJ, Cane DE, Christianson DW. Crystal structure determination of aristolochene synthase from the blue cheese mold, Penicillium roqueforti. The Journal of Biological Chemistry. 275: 25533-9. PMID 10825154 DOI: 10.1074/Jbc.M000433200 |
0.116 |
|
| 2004 |
Babine R, Rynkiewicz M, Jin L, Abdel-Meguid S. Towards an Experimental de Novo Design Protocol. The use of Protein Crystallography to Deconvolute Dynamic Combinatorial Processes Letters in Drug Design & Discovery. 1: 173-177. DOI: 10.2174/1570180043485617 |
0.113 |
|
| 2011 |
van Eijk M, Bruinsma L, Hartshorn KL, White MR, Rynkiewicz MJ, Seaton BA, Hemrika W, Romijn RA, van Balkom BW, Haagsman HP. Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses. The Journal of Biological Chemistry. 286: 20137-51. PMID 21489996 DOI: 10.1074/Jbc.M111.224469 |
0.111 |
|
| 1997 |
Rynkiewicz MJ, Seaton BA. Protein Crystallography in Medicine Advances in Molecular and Cell Biology. 22: 1-50. DOI: 10.1016/S1569-2558(08)60105-8 |
0.101 |
|
| 2019 |
van Eijk M, Hillaire MLB, Rimmelzwaan GF, Rynkiewicz MJ, White MR, Hartshorn KL, Hessing M, Koolmees PA, Tersteeg MH, van Es MH, Meijerhof T, Huckriede A, Haagsman HP. Enhanced Antiviral Activity of Human Surfactant Protein D by Site-Specific Engineering of the Carbohydrate Recognition Domain. Frontiers in Immunology. 10: 2476. PMID 31749796 DOI: 10.3389/fimmu.2019.02476 |
0.093 |
|
| 1993 |
Halperin J, Taratuska A, Rynkiewicz M, Nicholson-Weller A. Transient changes in erythrocyte membrane permeability are induced by sublytic amounts of the complement membrane attack complex (C5b-9) Blood. 81: 200-205. DOI: 10.1182/blood.v81.1.200.200 |
0.09 |
|
| 1993 |
Halperin J, Taratuska A, Rynkiewicz M, Nicholson-Weller A. Transient changes in erythrocyte membrane permeability are induced by sublytic amounts of the complement membrane attack complex (C5b-9) Blood. 81: 200-205. DOI: 10.1182/BLOOD.V81.1.200.BLOODJOURNAL811200 |
0.089 |
|
| 2006 |
Deng H, Bannister TD, Jin L, Babine RE, Quinn J, Nagafuji P, Celatka CA, Lin J, Lazarova TI, Rynkiewicz MJ, Bibbins F, Pandey P, Gorga J, Meyers HV, Abdel-Meguid SS, et al. Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine. Bioorganic & Medicinal Chemistry Letters. 16: 3049-54. PMID 16524727 DOI: 10.1016/J.Bmcl.2006.02.052 |
0.085 |
|
| 2014 |
Sharon J, Rynkiewicz MJ, Lu Z, Yang CY. Discovery of protective B-cell epitopes for development of antimicrobial vaccines and antibody therapeutics. Immunology. 142: 1-23. PMID 24219801 DOI: 10.1111/Imm.12213 |
0.076 |
|
| 2019 |
Patel D, Mez J, Vardarajan BN, Staley L, Chung J, Zhang X, Farrell JJ, Rynkiewicz MJ, Cannon-Albright LA, Teerlink CC, Stevens J, Corcoran C, Gonzalez Murcia JD, Lopez OL, Mayeux R, et al. Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry. Jama Network Open. 2: e191350. PMID 30924900 DOI: 10.1001/Jamanetworkopen.2019.1350 |
0.074 |
|
| 2006 |
Lin J, Deng H, Jin L, Pandey P, Quinn J, Cantin S, Rynkiewicz MJ, Gorga JC, Bibbins F, Celatka CA, Nagafuji P, Bannister TD, Meyers HV, Babine RE, Hayward NJ, et al. Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants. Journal of Medicinal Chemistry. 49: 7781-91. PMID 17181160 DOI: 10.1021/Jm060978S |
0.069 |
|
| 2019 |
Patel D, Mez J, Vardarajan BN, Staley L, Chung J, Zhang X, Farrell J, Rynkiewicz MJ, Cannon-Albright L, Teerlink C, Stevens J, Corcoran C, Murcia JDG, Lopez OL, Mayeux R, et al. O3-13-01: Highly Penetrant Late-Onset Alzheimer Disease Variants In Notch3 In Ashkenazi Jews Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4696 |
0.025 |
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