Wenxuan Cai - Publications

Affiliations: 
2013-2018 University of Wisconsin, Madison, Madison, WI 

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tucholski T, Cai W, Gregorich ZR, Bayne EF, Mitchell SD, McIlwain SJ, de Lange WJ, Wrobbel M, Karp H, Hite Z, Vikhorev PG, Marston SB, Lal S, Li A, Dos Remedios C, et al. Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics. Proceedings of the National Academy of Sciences of the United States of America. PMID 32968017 DOI: 10.1073/pnas.2006764117  0.774
2019 Lin Z, Wei L, Cai W, Zhu Y, Tucholski T, Mitchell SD, Guo W, Ford SP, Diffee GM, Ge Y. Simultaneous Quantification of Protein Expression and Modifications by Top-down Targeted Proteomics: A Case of the Sarcomeric Subproteome. Molecular & Cellular Proteomics : McP. 18: 594-605. PMID 33431132 DOI: 10.1074/mcp.TIR118.001086  0.804
2019 Cai W, Zhang J, De Lange WJ, Gregorich ZR, Karp H, Farrell ET, Mitchell ST, Tucholski T, Lin Z, Biermann M, McIlwain S, Ralphe JC, Kamp TJ, Ge Y. Unbiased Proteomics Method to Assess the Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation Research. PMID 31573406 DOI: 10.1161/Circresaha.119.315305  0.765
2019 Biermann M, Cai W, Lang D, Hermsen J, Profio L, Zhou Y, Czirok A, Isai DG, Napiwocki BN, Rodriguez AM, Brown ME, Woon MT, Shao A, Han T, Park D, et al. Epigenetic Priming of Human Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation. Stem Cells (Dayton, Ohio). PMID 31087611 DOI: 10.1002/Stem.3021  0.515
2019 Gregorich ZR, Patel JR, Cai W, Lin Z, Heurer R, Fitzsimons DP, Moss RL, Ge Y. Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium. The Journal of General Physiology. PMID 30642915 DOI: 10.1085/Jgp.201812214  0.775
2018 Lin Z, Wei L, Cai W, Zhu Y, Tucholski T, Mitchell SD, Guo W, Ford SP, Diffee GM, Ge Y. Simultaneous Quantification of Protein Expression and Modifications by Top-down Targeted Proteomics: A Case of Sarcomeric Subproteome. Molecular & Cellular Proteomics : McP. PMID 30591534 DOI: 10.1074/Mcp.Tir118.001086  0.809
2018 Cai W, Hite ZL, Lyu B, Wu Z, Lin Z, Gregorich ZR, Messer AE, McIlwain S, Marston SB, Kohmoto T, Ge Y. Temperature-sensitive sarcomeric protein post-translational modifications revealed by top-down proteomics. Journal of Molecular and Cellular Cardiology. PMID 30048711 DOI: 10.1016/J.Yjmcc.2018.07.247  0.765
2018 Martin-Garrido A, Biesiadecki BJ, Salhi HE, Shaifta Y, Dos Remedios CG, Ayuz-Guner S, Cai W, Ge Y, Avkiran M, Kentish JC. Monophosphorylation of cardiac troponin-I at Ser23/24 is sufficient to regulate cardiac myofibrillar Ca sensitivity and calpain-induced proteolysis. The Journal of Biological Chemistry. PMID 29669813 DOI: 10.1074/Jbc.Ra117.001292  0.539
2018 Wu Z, Tiambeng TN, Cai W, Chen B, Lin Z, Gregorich ZR, Ge Y. What is the Impact of Phosphorylation on the Mass Spectrometry Quantification of Intact Phosphoproteins? Analytical Chemistry. PMID 29565561 DOI: 10.1021/Acs.Analchem.7B05246  0.779
2018 Smelter DF, De Lange WJ, Cai W, Ge Y, Ralphe JC. The HCM-linked W792R mutation in cardiac myosin binding protein-C reduces C6 FnIII domain stability. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29451820 DOI: 10.1152/Ajpheart.00686.2017  0.533
2018 Kentish JC, Martin-Garrido A, Biesiadecki BJ, Salhi HE, Shaifta Y, Dos Remedios C, Ayaz-Guner S, Cai W, Ge Y, Avkiran M. P457Monophosphorylation of cardiac troponin-I at Ser23/24 regulates cardiac myofibrillar Ca2+ sensitivity and modulates calpain-induced proteolysis Cardiovascular Research. 114: S110-S110. DOI: 10.1093/Cvr/Cvy060.316  0.499
2017 Wei L, Gregorich ZR, Lin Z, Cai W, Jin Y, McKiernan SH, McIlwain S, Aiken JM, Moss RL, Diffee GM, Ge Y. Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications in Skeletal Muscles Identified by Top-down Proteomics. Molecular & Cellular Proteomics : McP. PMID 29046390 DOI: 10.1074/Mcp.Ra117.000124  0.774
2017 Chen B, Hwang L, Ochowicz W, Lin Z, Guardado-Alvarez TM, Cai W, Xiu L, Dani K, Colah C, Jin S, Ge Y. Coupling functionalized cobalt ferrite nanoparticle enrichment with online LC/MS/MS for top-down phosphoproteomics. Chemical Science. 8: 4306-4311. PMID 28660060 DOI: 10.1039/C6Sc05435H  0.789
2017 Gregorich ZR, Cai W, Lin Z, Chen AJ, Peng Y, Kohmoto T, Ge Y. Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. Journal of Molecular and Cellular Cardiology. PMID 28427997 DOI: 10.1016/J.Yjmcc.2017.04.002  0.767
2017 Cai W, Tucholski T, Chen B, Alpert AJ, McIlwain S, Kohmoto T, Jin S, Ge Y. Top-down Proteomics of Large Proteins up to 223 kDa Enabled by Serial Size Exclusion Chromatography Strategy. Analytical Chemistry. PMID 28406609 DOI: 10.1021/Acs.Analchem.7B00380  0.781
2017 Jin Y, Wei L, Cai W, Lin Z, Wu Z, Peng Y, Kohmoto T, Moss RL, Ge Y. Complete Characterization of Cardiac Myosin Heavy Chain (223 kDa) Enabled by Size-Exclusion Chromatography and Middle-down Mass Spectrometry. Analytical Chemistry. PMID 28366003 DOI: 10.1021/Acs.Analchem.7B00113  0.773
2017 Yang L, Gregorich ZR, Cai W, Zhang P, Young B, Gu Y, Zhang J, Ge Y. Quantitative Proteomics and Immunohistochemistry Reveal Insights into Cellular and Molecular Processes in the Infarct Border Zone One Month after Myocardial Infarction. Journal of Proteome Research. PMID 28347137 DOI: 10.1021/Acs.Jproteome.7B00107  0.753
2017 Cai W, Zhang J, de Lange WJ, Gregorich Z, Carter Ralphe J, Kamp T, Ge Y. Top-down proteomics for assessing the maturation of stem cell-derived cardiomyocytes Journal of Molecular and Cellular Cardiology. 112: 165-166. DOI: 10.1016/J.Yjmcc.2017.07.104  0.71
2017 Gregorich Z, Patel J, Cai W, Heurer R, Lin Z, Moss R, Ge Y. Deletion of the Z-disc Protein Enigma Homolog Depresses Cross-bridge Cycling Kinetics in Mouse Myocardium Journal of Molecular and Cellular Cardiology. 112: 142. DOI: 10.1016/J.Yjmcc.2017.07.037  0.722
2016 Cai W, Tucholski TM, Gregorich ZR, Ge Y. Top-down Proteomics for Comprehensive Analysis of Protein Isoforms and Modifications: Technology Advancements and Applications to Heart Diseases. Expert Review of Proteomics. PMID 27448560 DOI: 10.1080/14789450.2016.1209414  0.746
2016 Gregorich ZR, Peng Y, Cai W, Jin Y, Wei L, Chen AJ, McKiernan SH, Aiken JM, Moss RL, Diffee GM, Ge Y. Top-down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light Chain Phosphorylation that Contributes to Sarcopenic Muscle Dysfunction. Journal of Proteome Research. PMID 27362462 DOI: 10.1021/Acs.Jproteome.6B00244  0.767
2015 Cai W, Guner H, Gregorich ZR, Chen AJ, Ayaz-Guner S, Peng Y, Valeja SG, Liu X, Ge Y. MASH Suite Pro: A Comprehensive Software Tool for Top-down Proteomics. Molecular & Cellular Proteomics : McP. PMID 26598644 DOI: 10.1074/Mcp.O115.054387  0.766
2015 Chang YH, Ye L, Cai W, Lee Y, Guner H, Lee Y, Kamp TJ, Zhang J, Ge Y. Quantitative Proteomics Reveals Differential Regulation of Protein Expression in Recipient Myocardium after Trilineage Cardiovascular Cell Transplantation. Proteomics. PMID 26033914 DOI: 10.1002/Pmic.201500131  0.588
2015 Hwang L, Ayaz-Guner S, Gregorich ZR, Cai W, Valeja SG, Jin S, Ge Y. Specific enrichment of phosphoproteins using functionalized multivalent nanoparticles. Journal of the American Chemical Society. 137: 2432-5. PMID 25655481 DOI: 10.1021/Ja511833Y  0.742
2014 Peng Y, Gregorich ZR, Valeja SG, Zhang H, Cai W, Chen YC, Guner H, Chen AJ, Schwahn DJ, Hacker TA, Liu X, Ge Y. Top-down proteomics reveals concerted reductions in myofilament and Z-disc protein phosphorylation after acute myocardial infarction. Molecular & Cellular Proteomics : McP. 13: 2752-64. PMID 24969035 DOI: 10.1074/Mcp.M114.040675  0.787
2014 Guner H, Close PL, Cai W, Zhang H, Peng Y, Gregorich ZR, Ge Y. MASH Suite: a user-friendly and versatile software interface for high-resolution mass spectrometry data interpretation and visualization. Journal of the American Society For Mass Spectrometry. 25: 464-70. PMID 24385400 DOI: 10.1007/S13361-013-0789-4  0.737
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