Clemens Grassberger, PhD - Publications

Affiliations: 
2014 Medical Physics ETH Universität Zürich/Harvard University 
 2014- Radiation Oncology Harvard University, Cambridge, MA, United States 
Area:
Radiation Physics; Biophysics; Immunomodulation
Website:
https://gray.mgh.harvard.edu/people-directory/research/66-clemens-grassberger-phd

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McClatchy DM, Willers H, Hata AN, Piotrowska Z, Sequist LV, Paganetti H, Grassberger C. Modeling Resistance and Recurrence Patterns of Combined Targeted-Chemoradiotherapy Predicts Benefit of Shorter Induction Period. Cancer Research. 80: 5121-5133. PMID 32907839 DOI: 10.1158/0008-5472.Can-19-3883  1
2020 Sung W, Grassberger C, McNamara AL, Basler L, Ehrbar S, Tanadini-Lang S, Hong TS, Paganetti H. A Tumor-Immune Interaction Model for Hepatocellular Carcinoma based on measured Lymphocyte Counts in Patients undergoing Radiotherapy. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 32679308 DOI: 10.1016/J.Radonc.2020.07.025  1
2020 Pursley J, El Naqa I, Sanford NN, Noe B, Wo JY, Eyler CE, Hwang M, Brock KK, Yeap BY, Wolfgang JA, Hong TS, Grassberger C. Dosimetric analysis and normal tissue complication probability modeling of Child-Pugh score and Albumin-Bilirubin grade increase after hepatic irradiation. International Journal of Radiation Oncology, Biology, Physics. PMID 32353390 DOI: 10.1016/J.Ijrobp.2020.04.027  0.32
2020 Wang CC, McNamara AL, Shin J, Schuemann J, Grassberger C, Taghian AG, Jimenez RB, MacDonald SM, Paganetti H. End-of-range Radiobiological Effect on Rib Fractures in Patients Receiving Proton Therapy for Breast Cancer. International Journal of Radiation Oncology, Biology, Physics. PMID 32240774 DOI: 10.1016/J.Ijrobp.2020.03.012  1
2020 Hammi A, Paganetti H, Grassberger C. 4D blood flow model for dose calculation to circulating blood and lymphocytes. Physics in Medicine and Biology. 65: 055008. PMID 32119649 DOI: 10.1088/1361-6560/Ab6C41  1
2019 Grassberger C, McClatchy DM, Geng C, Kamran SC, Fintelmann F, Maruvka YE, Piotrowska Z, Willers H, Sequist LV, Hata AN, Paganetti H. Patient-specific tumor growth trajectories determine persistent and resistant cancer cell populations during treatment with targeted therapies. Cancer Research. PMID 31113818 DOI: 10.1158/0008-5472.Can-18-3652  1
2019 Li Y, Dykstra M, Best TD, Pursley J, Chopra N, Keane FK, Khandekar MJ, Sharp GC, Paganetti H, Willers H, Fintelmann FJ, Grassberger C. Differential inflammatory response dynamics in normal lung following stereotactic body radiation therapy with protons versus photons. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 136: 169-175. PMID 31015121 DOI: 10.1016/J.Radonc.2019.04.004  1
2019 Oesten H, von Neubeck C, Jakob A, Enghardt W, Krause M, McMahon SJ, Grassberger C, Paganetti H, Lühr A. Predicting Cancer Cell Survival Based on Measurable Cell Characteristics. Radiation Research. PMID 31008688 DOI: 10.1667/Rr15265.1  1
2019 Sanford NN, Pursley J, Noe B, Yeap BY, Goyal L, Clark JW, Allen JN, Blaszkowsky LS, Ryan DP, Ferrone CR, Tanabe KK, Qadan M, Crane CH, Koay EJ, Eyler C, ... ... Grassberger C, et al. Protons vs Photons for Unresectable Hepatocellular Carcinoma: Liver Decompensation and Overall Survival Proton Radiotherapy for Hepatocellular Carcinoma. International Journal of Radiation Oncology, Biology, Physics. PMID 30684667 DOI: 10.1016/J.Ijrobp.2019.01.076  0.32
2019 Pursley J, Wo JY, Wolfgang JA, Sanford NN, Noe B, Naqa IE, Hong TS, Grassberger C. Dosimetric Analysis and NTCP Model for Child-Pugh Score and ALBI Increase after Hepatic Irradiation International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.386  0.32
2019 Grassberger C, Shinnick D, Yeap BY, Hess CB, Baliga S, Weyman EA, Gallotto S, Lawell M, Bajaj B, Ebb DH, MacDonald S, Tarbell NJ, Yock TI. Circulating Lymphocyte Counts Early During Radiotherapy are Independently Predictive of Recurrence in Pediatric Medulloblastoma International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.215  0.32
2019 Ioakeim-Ioannidou M, Liu KX, Susko MS, Rao AD, Zaslowe-Dude C, Marcus KJ, Yock TI, Grassberger C, Braunstein SE, Haas-Kogan DA, Terezakis SA, MacDonald S. A Multi-Institutional Retrospective Comparative Analysis of Proton and Photon Therapy-Induced Hematologic Toxicity in Medulloblastoma Patients. International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.1164  0.32
2018 Chen Y, Grassberger C, Li J, Hong TS, Paganetti H. Impact of potentially variable RBE in liver proton therapy. Physics in Medicine and Biology. PMID 30183674 DOI: 10.1088/1361-6560/Aadf24  1
2018 Sung W, Jeong Y, Kim H, Jeong H, Grassberger C, Jung S, Ahn GO, Kim IH, Schuemann J, Lee K, Ye SJ. Computational Modeling and Clonogenic Assay for Radioenhancement of Gold Nanoparticles Using 3D Live Cell Images. Radiation Research. PMID 30142031 DOI: 10.1667/Rr15134.1  0.6
2018 Geng C, Paganetti H, Grassberger C. Author Correction: Prediction of Treatment Response for Combined Chemo- and Radiation Therapy for Non-Small Cell Lung Cancer Patients Using a Bio-Mathematical Model. Scientific Reports. 8: 12631. PMID 30115991 DOI: 10.1038/S41598-018-30761-7  1
2018 Underwood TSA, Grassberger C, Bass R, MacDonald SM, Meyersohn NM, Yeap BY, Jimenez RB, Paganetti H. Asymptomatic Late-phase Radiographic Changes Among Chest-Wall Patients Are Associated With a Proton RBE Exceeding 1.1. International Journal of Radiation Oncology, Biology, Physics. 101: 809-819. PMID 29976493 DOI: 10.1016/J.Ijrobp.2018.03.037  1
2018 Grassberger C, Hong TS, Hato T, Yeap BY, Wo JY, Tracy M, Bortfeld T, Wolfgang JA, Eyler CE, Goyal L, Clark JW, Crane CH, Koay EJ, Cobbold M, DeLaney TF, et al. Differential Association Between Circulating Lymphocyte Populations With Outcome After Radiation Therapy in Subtypes of Liver Cancer. International Journal of Radiation Oncology, Biology, Physics. PMID 29859792 DOI: 10.1016/J.Ijrobp.2018.04.026  0.32
2018 Botas P, Grassberger C, Sharp G, Paganetti H. Density overwrites of internal tumor volumes in intensity modulated proton therapy plans for mobile lung tumors. Physics in Medicine and Biology. 63: 035023. PMID 29219119 DOI: 10.1088/1361-6560/Aaa035  1
2018 Hoebel KV, Yeap BY, Wo JY, Eyler C, Wolfgang JA, Paganetti H, Hong TS, Grassberger C. Proton Therapy and the Role of Dosimetric Parameters as Predictors for Normal Tissue Complications after Liver-Directed Stereotactic Body Radiation Therapy International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.476  1
2017 Geng C, Paganetti H, Grassberger C. Prediction of Treatment Response for Combined Chemo- and Radiation Therapy for Non-Small Cell Lung Cancer Patients Using a Bio-Mathematical Model. Scientific Reports. 7: 13542. PMID 29051600 DOI: 10.1038/S41598-017-13646-Z  1
2017 Manem VSK, Grassberger C, Paganetti H. Predicting Organ-Specific Risk Interactions between Radiation and Chemotherapy in Secondary Cancer Survivors. Cancers. 9. PMID 28878202 DOI: 10.3390/Cancers9090119  1
2017 Grassberger C, Paganetti H. Varying relative biological effectiveness in proton therapy: knowledge gaps versus clinical significance. Acta Oncologica (Stockholm, Sweden). 56: 761-762. PMID 28464735 DOI: 10.1080/0284186X.2017.1316516  1
2017 Grassberger C, Scott JG, Paganetti H. Biomathematical Optimization of Radiation Therapy in the Era of Targeted Agents. International Journal of Radiation Oncology, Biology, Physics. 97: 13-17. PMID 27979444 DOI: 10.1016/J.Ijrobp.2016.09.008  1
2017 Hong TS, Grassberger C, Yeap BY, Wo JY, Goyal L, DeLaney TF, Zhu AX, Duda DG. Oral Scientific SessionsHepatocyte Growth Factor is Associated With Liver Dysfunction and Survival: Biomarker Results of a Phase 2 Study of Proton Beam Therapy in Patients with Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma International Journal of Radiation Oncology Biology Physics. 99. DOI: 10.1016/J.Ijrobp.2017.06.215  0.32
2016 Underwood T, Grassberger C, Willers H, MacDonald S, Jimenez R, Paganetti H. WE-FG-202-03: Quantitative CT-Based Analysis to Assess Lung Injury Following Proton Radiotherapy. Medical Physics. 43: 3827. PMID 28048337 DOI: 10.1118/1.4957915  1
2016 Botas P, Grassberger C, Sharp G, Qin N, Jia X, Jiang S, Paganetti H. SU-G-TeP1-06: Fast GPU Framework for Four-Dimensional Monte Carlo in Adaptive Intensity Modulated Proton Therapy (IMPT) for Mobile Tumors. Medical Physics. 43: 3653. PMID 28048238 DOI: 10.1118/1.4956996  1
2016 Grassberger C, Paganetti H. Methodologies in the modeling of combined chemo-radiation treatments. Physics in Medicine and Biology. 61: R344-R367. PMID 27758980 DOI: 10.1088/0031-9155/61/21/R344  1
2016 Grassberger C, Dinkelborg P, McNamara A, Schuemann JP, McMahon SJ, Willers H, Paganetti H, Wang M. Digital Holographic Microscopy for Nanoscale Dose Calculation and Assessing Gold Nanoparticle Uptake in Live Cells. International Journal of Radiation Oncology, Biology, Physics. 96: S169-S170. PMID 27675694 DOI: 10.1016/J.Ijrobp.2016.06.426  1
2016 Underwood TS, Grassberger C, MacDonald S, Jimenez RB, Paganetti H. Late-Phase Radiographic Changes in Lung Following Proton Irradiation of the Chest Wall. International Journal of Radiation Oncology, Biology, Physics. 96: S122. PMID 27675577 DOI: 10.1016/J.Ijrobp.2016.06.297  1
2016 Zureick AH, Pulsifer M, Niemierko A, Nichols AJ, Paganetti H, Grassberger C, Fullerton BC, Khan F, Tarbell NJ, MacDonald S, Yock TI. Elevated Proton Radiation Therapy Dose to Left Temporal Lobe or Whole-Brain Correlates With Decline in Full-Scale IQ Components for Pediatric CNS Tumor Survivors. International Journal of Radiation Oncology, Biology, Physics. 96: S120. PMID 27675573 DOI: 10.1016/J.Ijrobp.2016.06.293  1
2016 Verburg JM, Grassberger C, Dowdell S, Schuemann J, Seco J, Paganetti H. Automated Monte Carlo Simulation of Proton Therapy Treatment Plans. Technology in Cancer Research & Treatment. 15: NP35-NP46. PMID 26596915 DOI: 10.1177/1533034615614139  1
2016 Dowdell S, Grassberger C, Sharp G, Paganetti H. Fractionated Lung IMPT Treatments: Sensitivity to Setup Uncertainties and Motion Effects Based on Single-Field Homogeneity. Technology in Cancer Research & Treatment. 15: 689-96. PMID 26208837 DOI: 10.1177/1533034615595761  1
2015 Phillips J, Gueorguiev G, Grassberger C, Paganetti H, Sharp G. SU-E-T-639: Proton Dose Calculation for Irregular Motion Using a Sliding Interface. Medical Physics. 42: 3483. PMID 26128302 DOI: 10.1118/1.4925002  1
2015 Schuemann J, Giantsoudi D, Grassberger C, Moteabbed M, Min CH, Paganetti H. Assessing the Clinical Impact of Approximations in Analytical Dose Calculations for Proton Therapy. International Journal of Radiation Oncology, Biology, Physics. 92: 1157-64. PMID 26025779 DOI: 10.1016/J.Ijrobp.2015.04.006  0.52
2015 Grassberger C, Dowdell S, Sharp G, Paganetti H. Motion mitigation for lung cancer patients treated with active scanning proton therapy. Medical Physics. 42: 2462-9. PMID 25979039 DOI: 10.1118/1.4916662  1
2015 Grassberger C, Lomax A, Paganetti H. Characterizing a proton beam scanning system for Monte Carlo dose calculation in patients. Physics in Medicine and Biology. 60: 633-45. PMID 25549079 DOI: 10.1088/0031-9155/60/2/633  0.52
2015 Schuemann J, Giantsoudi D, Grassberger C, Moteabbed M, Min CH, Dowdell S, Paganetti H. SP-0111: Dose calculation accuracy in proton therapy Radiotherapy and Oncology. 115. DOI: 10.1016/S0167-8140(15)40109-4  1
2014 Knopf A, Nill S, Yohannes I, Graeff C, Dowdell S, Kurz C, Sonke JJ, Biegun AK, Lang S, McClelland J, Champion B, Fast M, Wölfelschneider J, Gianoli C, Rucinski A, ... ... Grassberger C, et al. Challenges of radiotherapy: report on the 4D treatment planning workshop 2013. Physica Medica : Pm : An International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (Aifb). 30: 809-15. PMID 25172392 DOI: 10.1016/J.Ejmp.2014.07.341  0.52
2014 Phillips J, Gueorguiev G, Shackleford JA, Grassberger C, Dowdell S, Paganetti H, Sharp GC. Computing proton dose to irregularly moving targets. Physics in Medicine and Biology. 59: 4261-73. PMID 25029239 DOI: 10.1088/0031-9155/59/15/4261  0.52
2014 Schuemann J, Dowdell S, Grassberger C, Min CH, Paganetti H. Site-specific range uncertainties caused by dose calculation algorithms for proton therapy. Physics in Medicine and Biology. 59: 4007-31. PMID 24990623 DOI: 10.1088/0031-9155/59/15/4007  1
2014 Grassberger C, Daartz J, Dowdell S, Ruggieri T, Sharp G, Paganetti H. Quantification of proton dose calculation accuracy in the lung. International Journal of Radiation Oncology, Biology, Physics. 89: 424-30. PMID 24726289 DOI: 10.1016/J.Ijrobp.2014.02.023  1
2013 Phillips J, Gueorguiev G, Shackleford J, Grassberger C, Dowdell S, Paganetti H, Sharp G. TU-A-108-06: Computing Proton Dose to Irregularly Moving Targets. Medical Physics. 40: 420. PMID 28518846 DOI: 10.1118/1.4815329  1
2013 Dowdell S, Grassberger C, Paganetti H. Four-dimensional Monte Carlo simulations demonstrating how the extent of intensity-modulation impacts motion effects in proton therapy lung treatments. Medical Physics. 40: 121713. PMID 24320499 DOI: 10.1118/1.4829500  1
2013 Giantsoudi D, Grassberger C, Craft D, Niemierko A, Trofimov A, Paganetti H. Linear energy transfer-guided optimization in intensity modulated proton therapy: feasibility study and clinical potential. International Journal of Radiation Oncology, Biology, Physics. 87: 216-22. PMID 23790771 DOI: 10.1016/J.Ijrobp.2013.05.013  1
2013 Dowdell S, Grassberger C, Sharp GC, Paganetti H. Interplay effects in proton scanning for lung: a 4D Monte Carlo study assessing the impact of tumor and beam delivery parameters. Physics in Medicine and Biology. 58: 4137-56. PMID 23689035 DOI: 10.1088/0031-9155/58/12/4137  1
2013 Zeng C, Giantsoudi D, Grassberger C, Goldberg S, Niemierko A, Paganetti H, Efstathiou JA, Trofimov A. Maximizing the biological effect of proton dose delivered with scanned beams via inhomogeneous daily dose distributions. Medical Physics. 40: 051708. PMID 23635256 DOI: 10.1118/1.4801897  1
2013 Carabe A, España S, Grassberger C, Paganetti H. Clinical consequences of relative biological effectiveness variations in proton radiotherapy of the prostate, brain and liver. Physics in Medicine and Biology. 58: 2103-17. PMID 23470339 DOI: 10.1088/0031-9155/58/7/2103  1
2013 Grassberger C, Dowdell S, Lomax A, Sharp G, Shackleford J, Choi N, Willers H, Paganetti H. Motion interplay as a function of patient parameters and spot size in spot scanning proton therapy for lung cancer. International Journal of Radiation Oncology, Biology, Physics. 86: 380-6. PMID 23462423 DOI: 10.1016/J.Ijrobp.2013.01.024  0.52
2012 Zeng C, Giantsoudi D, Grassberger C, Goldberg S, Niemierko A, Paganetti H, Trofimov A. SU-E-T-552: Maximizing the Biological Effect of Proton Dose Delivered with Scanned Beam. Medical Physics. 39: 3832. PMID 28518512 DOI: 10.1118/1.4735641  1
2012 Schuemann J, Shin J, Perl J, Grassberger C, Verburg J, Faddegon B, Paganetti H. SU-E-T-500: Pencil-Beam versus Monte Carlo Based Dose Calculation for Proton Therapy Patients with Complex Geometries. Clinical Use of the TOPAS Monte Carlo System. Medical Physics. 39: 3820. PMID 28518479 DOI: 10.1118/1.4735589  1
2012 Giantsoudi D, Grassberger C, Craft D, Niemierko A, Trofimov A, Paganetti H. TH-C-213AB-11: LET-Guided Biological Optimization in IMPT Medical Physics. 39: 3995-3996. DOI: 10.1118/1.4736300  1
2012 Paganetti H, Schuemann J, Grassberger C, Verburg J, Giantsoudi D, Moteabbed M, Min C, Testa M, Faddegon B, Perl J. Advanced Dose Calculation to Reduce Uncertainties in Treatment Planning and Delivery for Proton Therapy Patients International Journal of Radiation Oncology Biology Physics. 84. DOI: 10.1016/J.Ijrobp.2012.07.352  1
2012 Giantsoudi D, Grassberger C, Craft D, Niemierko A, Trofimov AV, Paganetti H. LET Guided Biological Optimization in IMPT: Implications on RBE Value International Journal of Radiation Oncology Biology Physics. 84. DOI: 10.1016/J.Ijrobp.2012.07.2261  1
2011 Grassberger C, Paganetti H. Elevated LET components in clinical proton beams. Physics in Medicine and Biology. 56: 6677-91. PMID 21965268 DOI: 10.1088/0031-9155/56/20/011  1
2011 Grassberger C, Trofimov A, Lomax A, Paganetti H. Variations in linear energy transfer within clinical proton therapy fields and the potential for biological treatment planning. International Journal of Radiation Oncology, Biology, Physics. 80: 1559-66. PMID 21163588 DOI: 10.1016/J.Ijrobp.2010.10.027  0.52
2010 Grassberger C, Trofimov A, Paganetti H. MO‐E‐BRB‐02: Biologically Optimized Treatment Planning for Proton Therapy: Monte Carlo Calculated Linear Energy Transfer Distributions in Patients Medical Physics. 37: 3355-3355. DOI: 10.1118/1.3469112  1
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