Neelam Shahani, Ph.D. - Publications

Affiliations: 
Neuroscience Scripps Florida, Jupiter, FL, United States 
Area:
Modulators of neurodegenerative disease relevant biochemical pathways.

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kim SH, Shahani N, Bae BI, Sbodio JI, Chung Y, Nakaso K, Paul BD, Sawa A. Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53. Human Molecular Genetics. PMID 27206983 DOI: 10.1093/Hmg/Ddw115  0.446
2015 Nakajima H, Kubo T, Ihara H, Hikida T, Danjo T, Nakatsuji M, Shahani N, Itakura M, Ono Y, Azuma YT, Inui T, Kamiya A, Sawa A, Takeuchi T. Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke. The Journal of Biological Chemistry. 290: 14493-503. PMID 25882840 DOI: 10.1074/Jbc.M114.635607  0.702
2015 Tyagi R, Shahani N, Gorgen L, Ferretti M, Pryor W, Chen PY, Swarnkar S, Worley PF, Karbstein K, Snyder SH, Subramaniam S. Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade. Cell Reports. PMID 25660019 DOI: 10.1016/J.Celrep.2015.01.014  0.425
2015 Tristan CA, Ramos A, Shahani N, Emiliani FE, Nakajima H, Noeh CC, Kato Y, Takeuchi T, Noguchi T, Kadowaki H, Sedlak TW, Ishizuka K, Ichijo H, Sawa A. Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade. The Journal of Biological Chemistry. 290: 56-64. PMID 25391652 DOI: 10.1074/Jbc.M114.596205  0.691
2015 Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A. DISC1 regulates trafficking and processing of APP and Aβ generation. Molecular Psychiatry. 20: 874-9. PMID 25224257 DOI: 10.1038/Mp.2014.100  0.679
2015 Zhang M, Sasaki H, Saitoh T, Koitabashi N, Zhu G, Tsujimura T, Lee D, Tristan C, Shahani N, Kariya T, Tsuchiya Y, Jaaro-Peled H, Slusher B, Kass D, Taguchi K, et al. NUCLEAR GLYCELALDEHYDE-3-PHOSPHATE DEHYDROGENASE SIGNALING MEDIATES PATHOLOGICAL CARDIAC HYPERTROPHY VIA P300 AND MYOCYTE ENHANCER FACTOR 2 Journal of the American College of Cardiology. 65: A2153. DOI: 10.1016/S0735-1097(15)62153-2  0.702
2014 Irmady K, Jackman KA, Padow VA, Shahani N, Martin LA, Cerchietti L, Unsicker K, Iadecola C, Hempstead BL. Mir-592 regulates the induction and cell death-promoting activity of p75NTR in neuronal ischemic injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3419-28. PMID 24573298 DOI: 10.1523/Jneurosci.1982-13.2014  0.306
2014 Mealer RG, Murray AJ, Shahani N, Subramaniam S, Snyder SH. Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy. The Journal of Biological Chemistry. 289: 3547-54. PMID 24324270 DOI: 10.1074/jbc.M113.536912  0.428
2013 Johnson AW, Jaaro-Peled H, Shahani N, Sedlak TW, Zoubovsky S, Burruss D, Emiliani F, Sawa A, Gallagher M. Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness. Proceedings of the National Academy of Sciences of the United States of America. 110: 12462-7. PMID 23840059 DOI: 10.1073/Pnas.1307925110  0.686
2012 Subramaniam S, Napolitano F, Mealer RG, Kim S, Errico F, Barrow R, Shahani N, Tyagi R, Snyder SH, Usiello A. Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia. Nature Neuroscience. 15: 191-3. PMID 22179112 DOI: 10.1038/Nn.2994  0.447
2012 Shahani N, Sawa A. Protein S-nitrosylation: role for nitric oxide signaling in neuronal death. Biochimica Et Biophysica Acta. 1820: 736-42. PMID 21803124 DOI: 10.1016/J.Bbagen.2011.07.010  0.576
2011 Shahani N, Sawa A. Nitric oxide signaling and nitrosative stress in neurons: role for S-nitrosylation. Antioxidants & Redox Signaling. 14: 1493-504. PMID 20812870 DOI: 10.1089/Ars.2010.3580  0.632
2011 Tristan C, Shahani N, Sedlak TW, Sawa A. The diverse functions of GAPDH: views from different subcellular compartments. Cellular Signalling. 23: 317-23. PMID 20727968 DOI: 10.1016/J.Cellsig.2010.08.003  0.716
2010 Shahani N, Young-Pearse T, Selkoe D, Sawa A. P2-247: Role of Disrupted-in-Schizophrenia-1 (DISC1) in amyloid precursor protein (APP) processing and Aβ generation Alzheimer's & Dementia. 6: S386-S387. DOI: 10.1016/J.Jalz.2010.05.1296  0.49
2008 Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, Shahani N, Thomas B, Dawson TM, Dawson VL, Snyder SH, Sawa A. Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Nature Cell Biology. 10: 866-73. PMID 18552833 DOI: 10.1038/Ncb1747  0.599
2006 Shahani N, Subramaniam S, Wolf T, Tackenberg C, Brandt R. Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6103-14. PMID 16738255 DOI: 10.1523/Jneurosci.4245-05.2006  0.335
2005 Brandt R, Hundelt M, Shahani N. Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. Biochimica Et Biophysica Acta. 1739: 331-54. PMID 15615650 DOI: 10.1016/J.Bbadis.2004.06.018  0.352
2002 Shahani N, Brandt R. Functions and malfunctions of the tau proteins. Cellular and Molecular Life Sciences : Cmls. 59: 1668-80. PMID 12475178 DOI: 10.1007/Pl00012495  0.359
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