| Year |
Citation |
Score |
| 2024 |
He F, Wu CG, Gao Y, Rahman SN, Zaoralová M, Papasergi-Scott MM, Gu TJ, Robertson MJ, Seven AB, Li L, Mathiesen JM, Skiniotis G. Allosteric modulation and G-protein selectivity of the Ca-sensing receptor. Nature. PMID 38326620 DOI: 10.1038/s41586-024-07055-2 |
0.821 |
|
| 2023 |
Vizurraga AL, Robertson MJ, Yu M, Skiniotis G, Tall GG. Hexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56. Molecular Pharmacology. 104: 28-41. PMID 37290962 DOI: 10.1124/molpharm.123.000688 |
0.639 |
|
| 2023 |
Krishna Kumar K, Robertson MJ, Thadhani E, Wang H, Suomivuori CM, Powers AS, Ji L, Nikas SP, Dror RO, Inoue A, Makriyannis A, Skiniotis G, Kobilka B. Structural basis for activation of CB1 by an endocannabinoid analog. Nature Communications. 14: 2672. PMID 37160876 DOI: 10.1038/s41467-023-37864-4 |
0.703 |
|
| 2022 |
Faouzi A, Wang H, Zaidi SA, DiBerto JF, Che T, Qu Q, Robertson MJ, Madasu MK, El Daibani A, Varga BR, Zhang T, Ruiz C, Liu S, Xu J, Appourchaux K, et al. Structure-based design of bitopic ligands for the µ-opioid receptor. Nature. PMID 36450356 DOI: 10.1038/s41586-022-05588-y |
0.792 |
|
| 2022 |
Qu Q, Huang W, Aydin D, Paggi JM, Seven AB, Wang H, Chakraborty S, Che T, DiBerto JF, Robertson MJ, Inoue A, Suomivuori CM, Roth BL, Majumdar S, Dror RO, et al. Insights into distinct signaling profiles of the µOR activated by diverse agonists. Nature Chemical Biology. PMID 36411392 DOI: 10.1038/s41589-022-01208-y |
0.808 |
|
| 2022 |
Robertson MJ, Papasergi-Scott MM, He F, Seven AB, Meyerowitz JG, Panova O, Peroto MC, Che T, Skiniotis G. Structure determination of inactive-state GPCRs with a universal nanobody. Nature Structural & Molecular Biology. PMID 36396979 DOI: 10.1038/s41594-022-00859-8 |
0.808 |
|
| 2022 |
Kaplan AL, Confair DN, Kim K, Barros-Álvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, ... ... Robertson MJ, et al. Bespoke library docking for 5-HT receptor agonists with antidepressant activity. Nature. PMID 36171289 DOI: 10.1038/s41586-022-05258-z |
0.794 |
|
| 2022 |
Cao C, Barros-Álvarez X, Zhang S, Kim K, Dämgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Hüttenhain R, et al. Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD. Neuron. PMID 36087581 DOI: 10.1016/j.neuron.2022.08.006 |
0.795 |
|
| 2022 |
Chen G, Wang X, Liao Q, Ge Y, Jiao H, Chen Q, Liu Y, Lyu W, Zhu L, van Zundert GCP, Robertson MJ, Skiniotis G, Du Y, Hu H, Ye RD. Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns. Nature Communications. 13: 5232. PMID 36064945 DOI: 10.1038/s41467-022-32822-y |
0.752 |
|
| 2022 |
Robertson MJ, Meyerowitz JG, Panova O, Borrelli K, Skiniotis G. Author Correction: Plasticity in ligand recognition at somatostatin receptors. Nature Structural & Molecular Biology. PMID 35804245 DOI: 10.1038/s41594-022-00813-8 |
0.612 |
|
| 2022 |
Robertson MJ, Skiniotis G. Development of OPLS-AA/M Parameters for Simulations of G Protein-Coupled Receptors and Other Membrane Proteins. Journal of Chemical Theory and Computation. PMID 35687850 DOI: 10.1021/acs.jctc.2c00015 |
0.591 |
|
| 2022 |
Barros-Álvarez X, Nwokonko RM, Vizurraga A, Matzov D, He F, Papasergi-Scott MM, Robertson MJ, Panova O, Yardeni EH, Seven AB, Kwarcinski FE, Su H, Peroto MC, Meyerowitz JG, Shalev-Benami M, et al. The tethered peptide activation mechanism of adhesion GPCRs. Nature. PMID 35418682 DOI: 10.1038/s41586-022-04575-7 |
0.763 |
|
| 2022 |
Meyerowitz JG, Robertson MJ, Barros-Álvarez X, Panova O, Nwokonko RM, Gao Y, Skiniotis G. The oxytocin signaling complex reveals a molecular switch for cation dependence. Nature Structural & Molecular Biology. PMID 35241813 DOI: 10.1038/s41594-022-00728-4 |
0.834 |
|
| 2022 |
Robertson MJ, Meyerowitz JG, Panova O, Borrelli K, Skiniotis G. Plasticity in ligand recognition at somatostatin receptors. Nature Structural & Molecular Biology. PMID 35210615 DOI: 10.1038/s41594-022-00727-5 |
0.677 |
|
| 2021 |
Han L, Qu Q, Aydin D, Panova O, Robertson MJ, Xu Y, Dror RO, Skiniotis G, Feng L. Structure and mechanism of the SGLT family of glucose transporters. Nature. PMID 34880492 DOI: 10.1038/s41586-021-04211-w |
0.744 |
|
| 2021 |
Mathiharan YK, Glaaser IW, Zhao Y, Robertson MJ, Skiniotis G, Slesinger PA. Structural insights into GIRK2 channel modulation by cholesterol and PIP. Cell Reports. 36: 109619. PMID 34433062 DOI: 10.1016/j.celrep.2021.109619 |
0.767 |
|
| 2021 |
Robertson MJ, Meyerowitz JG, Skiniotis G. Drug discovery in the era of cryo-electron microscopy. Trends in Biochemical Sciences. PMID 34281791 DOI: 10.1016/j.tibs.2021.06.008 |
0.682 |
|
| 2021 |
Gao Y, Robertson MJ, Rahman SN, Seven AB, Zhang C, Meyerowitz JG, Panova O, Hannan FM, Thakker RV, Bräuner-Osborne H, Mathiesen JM, Skiniotis G. Asymmetric activation of the calcium-sensing receptor homodimer. Nature. PMID 34194040 DOI: 10.1038/s41586-021-03691-0 |
0.828 |
|
| 2021 |
Seven AB, Barros-Álvarez X, de Lapeyrière M, Papasergi-Scott MM, Robertson MJ, Zhang C, Nwokonko RM, Gao Y, Meyerowitz JG, Rocher JP, Schelshorn D, Kobilka BK, Mathiesen JM, Skiniotis G. G-protein activation by a metabotropic glutamate receptor. Nature. PMID 34194039 DOI: 10.1038/s41586-021-03680-3 |
0.799 |
|
| 2020 |
Kim K, Che T, Panova O, DiBerto JF, Lyu J, Krumm BE, Wacker D, Robertson MJ, Seven AB, Nichols DE, Shoichet BK, Skiniotis G, Roth BL. Structure of a Hallucinogen-Activated Gq-Coupled 5-HT Serotonin Receptor. Cell. 182: 1574-1588.e19. PMID 32946782 DOI: 10.1016/J.Cell.2020.08.024 |
0.816 |
|
| 2020 |
Papasergi-Scott MM, Robertson MJ, Seven AB, Panova O, Mathiesen JM, Skiniotis G. Structures of metabotropic GABA receptor. Nature. PMID 32580208 DOI: 10.1038/S41586-020-2469-4 |
0.795 |
|
| 2020 |
Robertson MJ, van Zundert GCP, Borrelli K, Skiniotis G. GemSpot: A Pipeline for Robust Modeling of Ligands into Cryo-EM Maps. Structure (London, England : 1993). PMID 32413291 DOI: 10.1016/J.Str.2020.04.018 |
0.602 |
|
| 2020 |
Wouters E, Walraed J, Robertson MJ, Meyrath M, Szpakowska M, Chevigné A, Skiniotis G, Stove C. Assessment of Biased Agonism among Distinct Synthetic Cannabinoid Receptor Agonist Scaffolds. Acs Pharmacology & Translational Science. 3: 285-295. PMID 32296768 DOI: 10.1021/acsptsci.9b00069 |
0.662 |
|
| 2020 |
Staus DP, Hu H, Robertson MJ, Kleinhenz ALW, Wingler LM, Capel WD, Latorraca NR, Lefkowitz RJ, Skiniotis G. Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc. Nature. PMID 31945772 DOI: 10.1038/S41586-020-1954-0 |
0.823 |
|
| 2020 |
Huang W, Masureel M, Qianhui Q, Janetzko J, Inoue A, Kato HE, Robertson MJ, Nguyen KC, Glenn JS, Skiniotis G, Kobilka BK. Structure of the neurotensin receptor 1 in complex with β-arrestin 1. Nature. PMID 31945771 DOI: 10.1038/S41586-020-1953-1 |
0.733 |
|
| 2019 |
Allen AEA, Robertson MJ, Payne MC, Cole DJ. Development and Validation of the Quantum Mechanical Bespoke Protein Force Field. Acs Omega. 4: 14537-14550. PMID 31528808 DOI: 10.1021/acsomega.9b01769 |
0.555 |
|
| 2019 |
Maeda S, Qu Q, Robertson MJ, Skiniotis G, Kobilka BK. Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes. Science (New York, N.Y.). 364: 552-557. PMID 31073061 DOI: 10.1126/Science.Aaw5188 |
0.827 |
|
| 2019 |
Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laeremans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, et al. Author Correction: Structural insights into the activation of metabotropic glutamate receptors. Nature. PMID 30814739 DOI: 10.1038/S41586-019-0983-Z |
0.782 |
|
| 2019 |
Robertson MJ, Qian Y, Robinson MC, Tirado-Rives J, Jorgensen WL. Development and Testing of the OPLS-AA/M Force Field for RNA. Journal of Chemical Theory and Computation. PMID 30807148 DOI: 10.1021/Acs.Jctc.9B00054 |
0.454 |
|
| 2019 |
Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laermans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, et al. Structural insights into the activation of metabotropic glutamate receptors. Nature. PMID 30675062 DOI: 10.1038/s41586-019-0881-4 |
0.826 |
|
| 2018 |
Yan XC, Metrano AJ, Robertson MJ, Abascal NC, Tirado-Rives J, Miller SJ, Jorgensen WL. Molecular Dynamics Simulations of a Conformationally Mobile Peptide-Based Catalyst for Atroposelective Bromination. Acs Catalysis. 8: 9968-9979. PMID 30687577 DOI: 10.1021/Acscatal.8B03563 |
0.468 |
|
| 2018 |
Krishna Kumar K, Shalev-Benami M, Robertson MJ, Hu H, Banister SD, Hollingsworth SA, Latorraca NR, Kato HE, Hilger D, Maeda S, Weis WI, Farrens DL, Dror RO, Malhotra SV, Kobilka BK, et al. Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex. Cell. PMID 30639101 DOI: 10.1016/J.Cell.2018.11.040 |
0.826 |
|
| 2018 |
Trivedi-Parmar V, Robertson MJ, Cisneros JA, Krimmer SG, Jorgensen WL. Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. Chemmedchem. PMID 29575754 DOI: 10.1002/Cmdc.201800158 |
0.478 |
|
| 2018 |
Trivedi-Parmar V, Robertson MJ, Cisneros JA, Krimmer SG, Jorgensen WL. Front Cover: Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor (ChemMedChem 11/2018) Chemmedchem. 13: 1069-1069. DOI: 10.1002/Cmdc.201800277 |
0.408 |
|
| 2017 |
Robertson MJ, Tirado-Rives J, Jorgensen WL. Improved Treatment of Nucleosides and Nucleotides in the OPLS-AA Force Field. Chemical Physics Letters. 683: 276-280. PMID 29479109 DOI: 10.1016/J.Cplett.2017.02.049 |
0.451 |
|
| 2017 |
Dawson TK, Dziedzic P, Robertson MJ, Cisneros JA, Krimmer SG, Newton AS, Tirado-Rives J, Jorgensen WL. Adding a Hydrogen Bond May Not Help: Naphthyridinone vs Quinoline Inhibitors of Macrophage Migration Inhibitory Factor. Acs Medicinal Chemistry Letters. 8: 1287-1291. PMID 29259749 DOI: 10.1021/Acsmedchemlett.7B00384 |
0.447 |
|
| 2017 |
Yan XC, Robertson MJ, Tirado-Rives J, Jorgensen WL. Improved Description of Sulfur Charge Anisotropy in OPLS Force Fields. Model Development and Parameterization. The Journal of Physical Chemistry. B. PMID 28627890 DOI: 10.1021/Acs.Jpcb.7B04233 |
0.455 |
|
| 2017 |
Cisneros JA, Robertson MJ, Mercado BQ, Jorgensen WL. Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules. Acs Medicinal Chemistry Letters. 8: 124-127. PMID 28105287 DOI: 10.1021/Acsmedchemlett.6B00451 |
0.478 |
|
| 2016 |
Robertson MJ, Tirado-Rives J, Jorgensen WL. Performance of Protein-Ligand Force Fields for the Flavodoxin - Flavin Mononucleotide System. The Journal of Physical Chemistry Letters. PMID 27441982 DOI: 10.1021/Acs.Jpclett.6B01229 |
0.504 |
|
| 2016 |
Cisneros JA, Robertson MJ, Valhondo M, Jorgensen WL. A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors. Journal of the American Chemical Society. PMID 27299179 DOI: 10.1021/Jacs.6B04910 |
0.489 |
|
| 2016 |
Cisneros JA, Robertson MJ, Valhondo M, Jorgensen WL. Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorganic & Medicinal Chemistry Letters. PMID 27156768 DOI: 10.1016/J.Bmcl.2016.04.074 |
0.476 |
|
| 2015 |
Robertson MJ, Tirado-Rives J, Jorgensen WL. Improved Peptide and Protein Torsional Energetics with the OPLS-AA Force Field. Journal of Chemical Theory and Computation. 11: 3499-3509. PMID 26190950 DOI: 10.1021/Acs.Jctc.5B00356 |
0.454 |
|
| 2015 |
Dziedzic P, Cisneros JA, Robertson MJ, Hare AA, Danford NE, Baxter RH, Jorgensen WL. Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. Journal of the American Chemical Society. 137: 2996-3003. PMID 25697265 DOI: 10.1021/Ja512112J |
0.735 |
|
| 2015 |
Robertson MJ, Jorgensen WL. Illustrating Concepts in Physical Organic Chemistry with 3D Printed Orbitals Journal of Chemical Education. 92: 2113-2116. DOI: 10.1021/Acs.Jchemed.5B00682 |
0.442 |
|
| Show low-probability matches. |