| Year |
Citation |
Score |
| 2024 |
Yu Q, Barndt RJ, Shen Y, Sallam K, Tang Y, Chan SY, Wu JC, Liu Q, Wu H. Mitigation of Stress-induced Structural Remodeling and Functional Deficiency in iPSC-CMs with PLN R9C Mutation by Promoting Autophagy. Biorxiv : the Preprint Server For Biology. PMID 38659742 DOI: 10.1101/2024.04.17.589921 |
0.736 |
|
| 2023 |
Zhang P, Liu Y, Li C, Stine LD, Wang PH, Turnbull MW, Wu H, Liu Q. Ectopic expression of SARS-CoV-2 S and ORF-9B proteins alters metabolic profiles and impairs contractile function in cardiomyocytes. Frontiers in Cell and Developmental Biology. 11: 1110271. PMID 36910162 DOI: 10.3389/fcell.2023.1110271 |
0.302 |
|
| 2022 |
Barndt RJ, Liu Q, Tang Y, Haugh MP, Cui J, Chan SY, Wu H. Metabolic Maturation Exaggerates Abnormal Calcium Handling in a Knockout Human Pluripotent Stem Cell-Derived Cardiomyocyte Model of Danon Disease. Biomolecules. 13. PMID 36671453 DOI: 10.3390/biom13010069 |
0.434 |
|
| 2022 |
Strimaityte D, Tu C, Yanez A, Itzhaki I, Wu H, Wu JC, Yang H. Contractility and Calcium Transient Maturation in the Human iPSC-Derived Cardiac Microfibers. Acs Applied Materials & Interfaces. 14: 35376-35388. PMID 35901275 DOI: 10.1021/acsami.2c07326 |
0.786 |
|
| 2022 |
Feng W, Schriever H, Jiang S, Bais A, Wu H, Kostka D, Li G. Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency. Communications Biology. 5: 399. PMID 35488063 DOI: 10.1038/s42003-022-03346-4 |
0.337 |
|
| 2022 |
Kim BB, Wu H, Hao YA, Pan M, Chavarha M, Zhao Y, Westberg M, St-Pierre F, Wu JC, Lin MZ. A red fluorescent protein with improved monomericity enables ratiometric voltage imaging with ASAP3. Scientific Reports. 12: 3678. PMID 35256624 DOI: 10.1038/s41598-022-07313-1 |
0.3 |
|
| 2021 |
Barndt RJ, Ma N, Tang Y, Haugh MP, Alamri LS, Chan SY, Wu H. Modeling of dilated cardiomyopathy by establishment of isogenic human iPSC lines carrying phospholamban C25T (R9C) mutation (UPITTi002-A-1) using CRISPR/Cas9 editing. Stem Cell Research. 56: 102544. PMID 34583280 DOI: 10.1016/j.scr.2021.102544 |
0.353 |
|
| 2021 |
Lyu Z, Park J, Kim KM, Jin HJ, Wu H, Rajadas J, Kim DH, Steinberg GK, Lee W. A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke. Nature Biomedical Engineering. PMID 34385693 DOI: 10.1038/s41551-021-00744-7 |
0.303 |
|
| 2021 |
Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, et al. Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes. Stem Cell Reports. PMID 34019816 DOI: 10.1016/j.stemcr.2021.04.018 |
0.713 |
|
| 2021 |
Chirikian O, Goodyer WR, Dzilic E, Serpooshan V, Buikema JW, McKeithan W, Wu H, Li G, Lee S, Merk M, Galdos F, Beck A, Ribeiro AJS, Paige S, Mercola M, et al. CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes. Scientific Reports. 11: 3026. PMID 33542270 DOI: 10.1038/s41598-021-81860-x |
0.538 |
|
| 2020 |
Yang H, Shao N, Holmström A, Zhao X, Chour T, Chen H, Itzhaki I, Wu H, Ameen M, Cunningham NJ, Tu C, Zhao MT, Tarantal AF, Abilez OJ, Wu JC. Transcriptome Analysis of Non-Human Primate Induced Pluripotent Stem Cell-Derived Cardiomyocytes in 2D Monolayer Culture versus 3D Engineered Heart Tissue. Cardiovascular Research. PMID 33002105 DOI: 10.1093/cvr/cvaa281 |
0.84 |
|
| 2020 |
Buikema JW, Lee S, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, Paige SL, Lee D, Wu H, Paik DT, Rhee S, Tian L, Galdos FX, Puluca N, et al. Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes. Cell Stem Cell. 27: 50-63.e5. PMID 32619518 DOI: 10.1016/J.Stem.2020.06.001 |
0.541 |
|
| 2019 |
Wnorowski A, Sharma A, Chen H, Wu H, Shao NY, Sayed N, Liu C, Countryman S, Stodieck LS, Rubins KH, Wu SM, Lee PHU, Wu JC. Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. Stem Cell Reports. PMID 31708475 DOI: 10.1016/J.Stemcr.2019.10.006 |
0.832 |
|
| 2019 |
Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, et al. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. PMID 31316208 DOI: 10.1038/S41586-019-1406-X |
0.794 |
|
| 2019 |
Zhang H, Tian L, Shen M, Wu H, Gu M, Tu C, Paik DT, Wu JC. Generation of Quiescent Cardiac Fibroblasts from Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis. Circulation Research. PMID 31288631 DOI: 10.1161/Circresaha.119.315491 |
0.751 |
|
| 2019 |
Kernik DC, Morotti S, Wu H, Garg P, Duff HJ, Kurokawa J, Jalife J, Wu JC, Grandi E, Clancy CE. A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources. The Journal of Physiology. PMID 31278749 DOI: 10.1113/Jp277724 |
0.546 |
|
| 2019 |
Wu H, Yang H, Rhee JW, Zhang JZ, Lam CK, Sallam K, Chang ACY, Ma N, Lee J, Zhang H, Blau HM, Bers DM, Wu JC. Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. European Heart Journal. PMID 31219556 DOI: 10.1093/Eurheartj/Ehz326 |
0.827 |
|
| 2019 |
Belbachir N, Portero V, Al Sayed ZR, Gourraud JB, Dilasser F, Jesel L, Guo H, Wu H, Gaborit N, Guilluy C, Girardeau A, Bonnaud S, Simonet F, Karakachoff M, Pattier S, et al. RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome. European Heart Journal. PMID 31114854 DOI: 10.1093/Eurheartj/Ehz308 |
0.413 |
|
| 2019 |
Oh Y, Park Y, Cho JH, Wu H, Paulk NK, Liu LX, Kim N, Kay MA, Wu JC, Lin MZ. An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging. Nature Chemical Biology. PMID 30936501 DOI: 10.1038/S41589-019-0256-Z |
0.31 |
|
| 2019 |
Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, et al. A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles. Cell Stem Cell. PMID 30880024 DOI: 10.1016/J.Stem.2019.02.015 |
0.815 |
|
| 2018 |
Qin X, Chen H, Yang H, Wu H, Zhao X, Wang H, Chour T, Neofytou E, Ding D, Daldrup-Link H, Heilshorn SC, Li K, Wu JC. Photoacoustic Imaging of Embryonic Stem Cell-Derived Cardiomyocytes in Living Hearts with Ultrasensitive Semiconducting Polymer Nanoparticles. Advanced Functional Materials. 28. PMID 30473658 DOI: 10.1002/Adfm.201704939 |
0.768 |
|
| 2018 |
Churko JM, Garg P, Treutlein B, Venkatasubramanian M, Wu H, Lee J, Wessells QN, Chen SY, Chen WY, Chetal K, Mantalas G, Neff N, Jabart E, Sharma A, Nolan GP, et al. Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis. Nature Communications. 9: 4906. PMID 30464173 DOI: 10.1038/S41467-018-07333-4 |
0.828 |
|
| 2018 |
Tang L, Yao F, Wang H, Wang X, Shen J, Dai B, Wu H, Zhou D, Guo F, Wang J, Li T, Wang H, Gong T, Su J, Wang L, et al. Inhibition of TRPC1 prevents cardiac hypertrophy via NF-κB signaling pathway in human pluripotent stem cell-derived cardiomyocytes. Journal of Molecular and Cellular Cardiology. PMID 30423318 DOI: 10.1016/j.yjmcc.2018.10.020 |
0.597 |
|
| 2018 |
Ma N, Zhang J, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC. Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells. Circulation. PMID 29914921 DOI: 10.1161/Circulationaha.117.032273 |
0.808 |
|
| 2018 |
Lee J, Shao NY, Paik DT, Wu H, Guo H, Termglinchan V, Churko JM, Kim Y, Kitani T, Zhao MT, Zhang Y, Wilson KD, Karakikes I, Snyder MP, Wu JC. SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation. Cell Stem Cell. 22: 428-444.e5. PMID 29499155 DOI: 10.1016/J.Stem.2018.02.005 |
0.778 |
|
| 2018 |
Wnorowski A, Sharma A, Chen H, Wu H, Shao N, Churko JM, Matsa E, Countryman S, Rubins K, Wu SM, Lee PH, Wu JC. Abstract 379: Effects of Microgravity on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.379 |
0.772 |
|
| 2018 |
Wu H, Yang H, Rhee J, Zhang J, Lam CK, Sallam K, Chang AC, Ma N, Blau H, Bers D, Wu J. Abstract 243: Modeling of Diastolic Dysfunction in Induced Pluripotent Stem Cell-derived Cardiomyocytes From Hypertrophic Cardiomyopathy Patients Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.243 |
0.782 |
|
| 2018 |
Zhang JZ, Termglinchan V, Itzhaki I, Wang V, Shao N, Chang A, Ma N, Liu C, Kitani T, Sayed N, Wu H, Lam C, Blau H, Wu J. Abstract 217:
TBX5
Clover2
/NKX2-5
TagRFP
hiPSCs for Simultaneously Isolating Lineage-Specific Cardiovascular Cells Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.217 |
0.799 |
|
| 2018 |
Lam CK, Ma N, Rhee J, Kitani T, Zhang J, Shrestha R, Wu H, Wu JC. Identifying the Novel Role of a Presenilin-2 Mutation in Arrhythmogenicity using Patient Specific Induced Pluripotent Stem Cells Derived Cardiomyocytes Journal of Molecular and Cellular Cardiology. 124: 109. DOI: 10.1016/J.Yjmcc.2018.07.080 |
0.806 |
|
| 2017 |
Chamberland S, Yang HH, Pan MM, Evans SW, Guan S, Chavarha M, Yang Y, Salesse C, Wu H, Wu JC, Clandinin TR, Toth K, Lin MZ, St-Pierre F. Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators. Elife. 6. PMID 28749338 DOI: 10.7554/Elife.25690 |
0.305 |
|
| 2017 |
Lee WH, Chen W, Shao NY, Xiao D, Qin X, Baker N, Bae HRM, Shukla P, Wu H, Kodo K, Ong SG, Wu JC. Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- Versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cells (Dayton, Ohio). PMID 28710827 DOI: 10.1002/Stem.2669 |
0.842 |
|
| 2017 |
Serpooshan V, Chen P, Wu H, Lee S, Sharma A, Hu DA, Venkatraman S, Ganesan AV, Usta OB, Yarmush M, Yang F, Wu JC, Demirci U, Wu SM. Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. Biomaterials. 131: 47-57. PMID 28376365 DOI: 10.1016/J.Biomaterials.2017.03.037 |
0.547 |
|
| 2017 |
Karakikes I, Termglinchan V, Cepeda DA, Lee J, Diecke S, Hendel A, Itzhaki I, Ameen M, Shrestha R, Wu H, Ma N, Shao NY, Seeger T, Woo NA, Wilson KD, et al. A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases. Circulation Research. PMID 28246128 DOI: 10.1161/Circresaha.116.309948 |
0.825 |
|
| 2017 |
Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, et al. High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Science Translational Medicine. 9. PMID 28202772 DOI: 10.1126/Scitranslmed.Aaf2584 |
0.81 |
|
| 2016 |
Chao MP, Gentles AJ, Chatterjee S, Lan F, Reinisch A, Corces MR, Xavy S, Shen J, Haag D, Chanda S, Sinha R, Morganti RM, Nishimura T, Ameen M, Wu H, et al. Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease. Cell Stem Cell. PMID 28089908 DOI: 10.1016/J.Stem.2016.11.018 |
0.669 |
|
| 2016 |
Liang P, Sallam K, Wu H, Li Y, Itzhaki I, Garg P, Zhang Y, Vermglinchan V, Lan F, Gu M, Gong T, Zhuge Y, He C, Ebert AD, Sanchez-Freire V, et al. Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome. Journal of the American College of Cardiology. 68: 2086-2096. PMID 27810048 DOI: 10.1016/J.Jacc.2016.07.779 |
0.778 |
|
| 2016 |
Lee J, Jung SM, Ebert AD, Wu H, Diecke S, Kim Y, Yi H, Park SH, Ju JH. Generation of Functional Cardiomyocytes from the Synoviocytes of Patients with Rheumatoid Arthritis via Induced Pluripotent Stem Cells. Scientific Reports. 6: 32669. PMID 27609119 DOI: 10.1038/srep32669 |
0.806 |
|
| 2016 |
Matsa E, Burridge PW, Yu KH, Ahrens JH, Termglinchan V, Wu H, Liu C, Shukla P, Sayed N, Churko JM, Shao N, Woo NA, Chao AS, Gold JD, Karakikes I, et al. Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro. Cell Stem Cell. PMID 27545504 DOI: 10.1016/J.Stem.2016.07.006 |
0.804 |
|
| 2016 |
Davis J, Davis LC, Correll RN, Makarewich CA, Schwanekamp JA, Moussavi-Harami F, Wang D, York AJ, Wu H, Houser SR, Seidman CE, Seidman JG, Regnier M, Metzger JM, Wu JC, et al. A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy. Cell. PMID 27114035 DOI: 10.1016/J.Cell.2016.04.002 |
0.518 |
|
| 2016 |
Burridge PW, Li YF, Matsa E, Wu H, Ong SG, Sharma A, Holmström A, Chang AC, Coronado MJ, Ebert AD, Knowles JW, Telli ML, Witteles RM, Blau HM, Bernstein D, et al. Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. Nature Medicine. PMID 27089514 DOI: 10.1038/Nm.4087 |
0.831 |
|
| 2016 |
He C, Hu H, Wilson KD, Wu H, Feng J, Xia S, Churko J, Qu K, Chang HY, Wu JC. Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart. Circulation. Cardiovascular Genetics. PMID 26896382 DOI: 10.1161/Circgenetics.115.001264 |
0.779 |
|
| 2015 |
Wu H, Lee J, Vincent LG, Wang Q, Gu M, Lan F, Churko JM, Sallam KI, Matsa E, Sharma A, Gold JD, Engler AJ, Xiang YK, Bers DM, Wu JC. Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. Cell Stem Cell. 17: 89-100. PMID 26095046 DOI: 10.1016/J.Stem.2015.04.020 |
0.784 |
|
| 2015 |
Burridge PW, Diecke S, Matsa E, Sharma A, Wu H, Wu JC. Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes. Methods in Molecular Biology (Clifton, N.J.). PMID 25690476 DOI: 10.1007/7651_2015_196 |
0.75 |
|
| 2015 |
Gu M, Mordwinkin NM, Kooreman NG, Lee J, Wu H, Hu S, Churko JM, Diecke S, Burridge PW, He C, Barron FE, Ong SG, Gold JD, Wu JC. Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism. European Heart Journal. 36: 806-16. PMID 25368203 DOI: 10.1093/Eurheartj/Ehu411 |
0.772 |
|
| 2014 |
Ebert AD, Kodo K, Liang P, Wu H, Huber BC, Riegler J, Churko J, Lee J, de Almeida P, Lan F, Diecke S, Burridge PW, Gold JD, Mochly-Rosen D, Wu JC. Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system. Science Translational Medicine. 6: 255ra130. PMID 25253673 DOI: 10.1126/Scitranslmed.3009027 |
0.798 |
|
| 2014 |
Wang Y, Liang P, Lan F, Wu H, Lisowski L, Gu M, Hu S, Kay MA, Urnov FD, Shinnawi R, Gold JD, Gepstein L, Wu JC. Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing. Journal of the American College of Cardiology. 64: 451-9. PMID 25082577 DOI: 10.1016/J.Jacc.2014.04.057 |
0.822 |
|
| 2014 |
Sharma A, Marceau C, Hamaguchi R, Burridge PW, Rajarajan K, Churko JM, Wu H, Sallam KI, Matsa E, Sturzu AC, Che Y, Ebert A, Diecke S, Liang P, Red-Horse K, et al. Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform. Circulation Research. 115: 556-66. PMID 25015077 DOI: 10.1161/Circresaha.115.303810 |
0.812 |
|
| 2013 |
Navarrete EG, Liang P, Lan F, Sanchez-Freire V, Simmons C, Gong T, Sharma A, Burridge PW, Patlolla B, Lee AS, Wu H, Beygui RE, Wu SM, Robbins RC, Bers DM, et al. Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. Circulation. 128: S3-13. PMID 24030418 DOI: 10.1161/Circulationaha.112.000570 |
0.803 |
|
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