Masakazu Toi - Publications

Affiliations: 
1990-1992 University of Oxford, Oxford, United Kingdom 

290 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ganz PA, Bandos H, Španić T, Friedman S, Müller V, Kuemmel S, Delaloge S, Brain E, Toi M, Yamauchi H, de Dueñas EM, Armstrong A, Im SA, Song CG, Zheng H, et al. Patient-Reported Outcomes in OlympiA: A Phase III, Randomized, Placebo-Controlled Trial of Adjuvant Olaparib in g Mutations and High-Risk Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2301214. PMID 38301187 DOI: 10.1200/JCO.23.01214  0.323
2024 Saldajeno DP, Kawaoka S, Masuda N, Tanaka S, Bando H, Nishimura T, Kadoya T, Yamanaka T, Imoto S, Velaga RM, Tamura N, Aruga T, Ikeda K, Fukui Y, Maeshima Y, ... ... Toi M, et al. Time-series blood cytokine profiles correlate with treatment responses in triple-negative breast cancer patients. British Journal of Cancer. PMID 38238427 DOI: 10.1038/s41416-023-02527-0  0.479
2024 Sagara Y, Kumamaru H, Niikura N, Miyashita M, Konishi T, Iwamoto T, Sanuki N, Tanakura K, Nagahashi M, Hayashi N, Yoshida M, Kinukawa N, Watanabe C, Toi M, Saji S. 2020 Annual Report of National Clinical Database-Breast Cancer Registry: 10-year mortality of elderly breast cancer patients in Japan. Breast Cancer (Tokyo, Japan). PMID 38180641 DOI: 10.1007/s12282-023-01532-8  0.428
2023 Costa L, Kumar R, Villarreal-Garza C, Sinha S, Saini S, Semwal J, Saxsena V, Zamre V, Chintamani C, Ray M, Shimizu C, Gusic LH, Toi M, Lipton A. Diagnostic delays in breast cancer among young women: An emphasis on healthcare providers. Breast (Edinburgh, Scotland). 73: 103623. PMID 38219460 DOI: 10.1016/j.breast.2023.103623  0.354
2023 Yamaguchi A, Kawaguchi K, Kawanishi K, Maeshima Y, Nakakura A, Kataoka TR, Takahara S, Nakagawa S, Yonezawa A, Takada M, Kawashima M, Kawaguchi-Sakita N, Kotake T, Suzuki E, Shimizu H, ... ... Toi M, et al. Comparison of cisplatin-based versus standard preoperative chemotherapy in patients with operable triple-negative breast cancer: propensity score matching and inverse probability of treatment weighting analysis. Breast Cancer Research and Treatment. PMID 38123790 DOI: 10.1007/s10549-023-07163-z  0.42
2023 Miyashita M, Kumamaru H, Niikura N, Sagara Y, Konishi T, Iwamoto T, Sanuki N, Tanakura K, Nagahashi M, Hayashi N, Yoshida M, Watanabe C, Kinukawa N, Toi M, Saji S. Annual report of the Japanese Breast Cancer Registry for 2019. Breast Cancer (Tokyo, Japan). PMID 38044372 DOI: 10.1007/s12282-023-01526-6  0.431
2023 García-Sáenz JA, Marmé F, Untch M, Bonnefoi H, Kim SB, Bear H, Mc Carthy N, Gelmon K, Martin M, Kelly CM, Reimer T, Toi M, Law E, Bhattacharyya H, Gnant M, et al. Patient-reported outcomes in high-risk HR+ /HER2- early breast cancer patients treated with endocrine therapy with or without palbociclib within the randomized PENELOPE study. European Journal of Cancer (Oxford, England : 1990). 196: 113420. PMID 38000218 DOI: 10.1016/j.ejca.2023.113420  0.361
2023 Li W, Kawaguchi K, Tanaka S, He C, Maeshima Y, Suzuki E, Toi M. Cellular senescence triggers intracellular acidification and lysosomal pH alkalinized via ATP6AP2 attenuation in breast cancer cells. Communications Biology. 6: 1147. PMID 37993606 DOI: 10.1038/s42003-023-05433-6  0.425
2023 Nishikawa Y, Agatsuma N, Utsumi T, Funakoshi T, Mori Y, Nakamura Y, Hoshino N, Horimatsu T, Saito T, Kashihara S, Fukuyoshi J, Goto R, Toi M, Takahashi Y, Nakayama T. Medical care costs according to the stage and subtype of breast cancer in a municipal setting: a case study of Hachioji City, Japan. Breast Cancer (Tokyo, Japan). PMID 37982959 DOI: 10.1007/s12282-023-01517-7  0.359
2023 Goetz MP, Hamilton EP, Campone M, Hurvitz SA, Cortes J, Johnston S, Llombart-Cussac A, Kaufman PA, Toi M, Jerusalem G, Graham H, Wang H, Jansen VM, Litchfield LM, Martín M. Landscape of baseline and acquired genomic alterations in circulating tumor DNA with abemaciclib alone or with endocrine therapy in advanced breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37889120 DOI: 10.1158/1078-0432.CCR-22-3573  0.36
2023 Kuo SH, Tseng LM, Chen ST, Sagara Y, Chang YC, Yeh HT, Kuo YL, Hung CC, Lu TP, Lee YH, Toi M, Huang CS. Radiotherapy versus low-dose tamoxifen following breast-conserving surgery for low-risk and estrogen receptor-positive breast ductal carcinoma in situ: an international open-label randomized non-inferiority trial (TBCC-ARO DCIS Trial). Bmc Cancer. 23: 865. PMID 37710198 DOI: 10.1186/s12885-023-11291-6  0.392
2023 Takada M, Imoto S, Ishida T, Ito Y, Iwata H, Masuda N, Mukai H, Saji S, Ikeda T, Haga H, Saeki T, Aogi K, Sugie T, Ueno T, Ohno S, ... ... Toi M, et al. A risk-based subgroup analysis of the effect of adjuvant S-1 in estrogen receptor-positive, HER2-negative early breast cancer. Breast Cancer Research and Treatment. 202: 485-496. PMID 37676450 DOI: 10.1007/s10549-023-07099-4  0.385
2023 Toi M, Aruga T. SERDs for primary breast cancer. The Lancet. Oncology. 24: 947-949. PMID 37657466 DOI: 10.1016/S1470-2045(23)00291-7  0.501
2023 Liu L, Kawashima M, Sugimoto M, Sonomura K, Pu F, Li W, Takeda M, Goto T, Kawaguchi K, Sato TA, Toi M. Discovery of lipid profiles in plasma-derived extracellular vesicles as biomarkers for breast cancer diagnosis. Cancer Science. PMID 37608343 DOI: 10.1111/cas.15935  0.453
2023 Masuyama M, Masuda N, Kawaguchi H, Yamamoto Y, Saji S, Nakayama T, Aogi K, Anan K, Ohtani S, Sato N, Takano T, Tokunaga E, Nakamura S, Hasegawa Y, Hattori M, ... ... Toi M, et al. Fulvestrant with or without anti-HER2 therapy in patients in a postmenopausal hormonal state and with ER-positive HER2-positive advanced or metastatic breast cancer: A subgroup analysis of data from the Safari study (JBCRG-C06). Cancer Medicine. PMID 37525895 DOI: 10.1002/cam4.6390  0.372
2023 Nishimura T, Kakiuchi N, Yoshida K, Sakurai T, Kataoka TR, Kondoh E, Chigusa Y, Kawai M, Sawada M, Inoue T, Takeuchi Y, Maeda H, Baba S, Shiozawa Y, Saiki R, ... ... Toi M, et al. Evolutionary histories of breast cancer and related clones. Nature. PMID 37495687 DOI: 10.1038/s41586-023-06333-9  0.448
2023 Kobayashi K, Masuda N, Mizuno T, Miura K, Tokuda Y, Yoshinami T, Kawaguchi H, Ohtani S, Saeki T, Toi M, Takeuchi M, Ito Y. Phase II trial of biweekly administration with eribulin after three cycles of induction therapy in hormone receptor-positive, HER2-negative metastatic breast cancer (JACCRO BC-03). Breast Cancer Research and Treatment. PMID 37480384 DOI: 10.1007/s10549-023-07030-x  0.422
2023 Adachi Y, Asaga S, Kumamaru H, Kinugawa N, Sagara Y, Niikura N, Jinno H, Saji S, Toi M. Analysis of prognosis in different subtypes of invasive lobular carcinoma using the Japanese National Cancer Database-Breast Cancer Registry. Breast Cancer Research and Treatment. PMID 37479943 DOI: 10.1007/s10549-023-07022-x  0.309
2023 Ohashi A, Kataoka M, Iima M, Honda M, Ota R, Urushibata Y, Dominik Nickel M, Toi M, Zackrisson S, Nakamoto Y. A multiparametric approach to predict triple-negative breast cancer including parameters derived from ultrafast dynamic contrast-enhanced MRI. European Radiology. PMID 37286791 DOI: 10.1007/s00330-023-09730-w  0.46
2023 Yuge S, Miyake KK, Ishimori T, Kataoka M, Matsumoto Y, Torii M, Yakami M, Isoda H, Takakura K, Morita S, Takada M, Toi M, Nakamoto Y. Performance of dedicated breast PET in breast cancer screening: comparison with digital mammography plus digital breast tomosynthesis and ultrasound. Annals of Nuclear Medicine. PMID 37280410 DOI: 10.1007/s12149-023-01846-9  0.448
2023 Turner NC, Oliveira M, Howell SJ, Dalenc F, Cortes J, Gomez Moreno HL, Hu X, Jhaveri K, Krivorotko P, Loibl S, Morales Murillo S, Okera M, Park YH, Sohn J, Toi M, et al. Capivasertib in Hormone Receptor-Positive Advanced Breast Cancer. The New England Journal of Medicine. 388: 2058-2070. PMID 37256976 DOI: 10.1056/NEJMoa2214131  0.394
2023 Yamada Y, Simon R, Iwane K, Nakanishi Y, Takeuchi Y, Yoshizawa A, Takada M, Toi M, Haga H, Marx A, Sauter G. An exploratory study for tuft cells in the breast and their relevance in triple-negative breast cancer: the possible relationship of SOX9. Bmc Cancer. 23: 438. PMID 37179317 DOI: 10.1186/s12885-023-10949-5  0.513
2023 Yamauchi H, Toi M, Takayama S, Nakamura S, Takano T, Cui K, Campbell C, De Vos L, Geyer C, Tutt A. Correction: Adjuvant olaparib in the subset of patients from Japan with BRCA1- or BRCA2-mutated high-risk early breast cancer from the phase 3 OlympiA trial. Breast Cancer (Tokyo, Japan). PMID 37171785 DOI: 10.1007/s12282-023-01468-z  0.388
2023 He C, Konishi R, Harata A, Nakamura Y, Mizuno R, Yoda M, Toi M, Kawaguchi K, Kawaoka S. Serum amyloid alpha 1-2 are not required for liver inflammation in the 4T1 murine breast cancer model. Frontiers in Immunology. 14: 1097788. PMID 36817472 DOI: 10.3389/fimmu.2023.1097788  0.355
2023 Vandenbon A, Mizuno R, Konishi R, Onishi M, Masuda K, Kobayashi Y, Kawamoto H, Suzuki A, He C, Nakamura Y, Kawaguchi K, Toi M, Shimizu M, Tanaka Y, Suzuki Y, et al. Murine breast cancers disorganize the liver transcriptome in a zonated manner. Communications Biology. 6: 97. PMID 36694005 DOI: 10.1038/s42003-023-04479-w  0.365
2023 Imoto S, Wang K, Bi XW, Liu G, Im YH, Im SA, Sim SH, Ueno T, Futamura M, Toi M, Fujiwara Y, Ahn SG, Lee JE, Park YH, Takao S, et al. Survival advantage of locoregional and systemic therapy in oligometastatic breast cancer: an international retrospective cohort study (OLIGO-BC1). Breast Cancer (Tokyo, Japan). PMID 36689066 DOI: 10.1007/s12282-023-01436-7  0.389
2022 Nakayama Y, Hanada M, Koda H, Sugimoto M, Takada M, Toi M. Breast cancer detection using volatile compound profiles in exhaled breath via selected ion-flow tube mass spectrometry. Journal of Breath Research. 17. PMID 36541460 DOI: 10.1088/1752-7163/aca696  0.344
2022 Kawaguchi H, Yamamoto Y, Saji S, Masuda N, Nakayama T, Aogi K, Anan K, Ohtani S, Sato N, Takano T, Tokunaga E, Nakamura S, Hasegawa Y, Hattori M, Fujisawa T, ... ... Toi M, et al. Retrospective study on the effectiveness of medroxyprogesterone acetate in the treatment of ER-positive/HER2-negative post-menopausal advanced breast cancer: an additional analysis of the JBCRG-C06 Safari study. Japanese Journal of Clinical Oncology. PMID 36484305 DOI: 10.1093/jjco/hyac184  0.322
2022 Yuge S, Miyake KK, Ishimori T, Kataoka M, Matsumoto Y, Fujimoto K, Sugie T, Toi M, Nakamoto Y. Reproducibility assessment of uptake on dedicated breast PET for noise discrimination. Annals of Nuclear Medicine. PMID 36434200 DOI: 10.1007/s12149-022-01809-6  0.328
2022 Mori T, Okamoto Y, Mu A, Ide Y, Yoshimura A, Senda N, Inagaki-Kawata Y, Kawashima M, Kitao H, Tokunaga E, Miyoshi Y, Ohsumi S, Tsugawa K, Ohta T, Katagiri T, ... ... Toi M, et al. Lack of impact of the ALDH2 rs671 variant on breast cancer development in Japanese BRCA1/2-mutation carriers. Cancer Medicine. PMID 36345163 DOI: 10.1002/cam4.5430  0.386
2022 Toi M, Boyle F, Im YH, Reinisch M, Molthrop D, Jiang Z, Wei R, Sapunar F, Grimes BR, Nabinger SC, Johnston SRD. Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1. The Oncologist. PMID 36342342 DOI: 10.1093/oncolo/oyac234  0.411
2022 Kawaguchi K, Maeshima Y, Toi M. Tumor immune microenvironment and systemic response in breast cancer. Medical Oncology (Northwood, London, England). 39: 208. PMID 36175677 DOI: 10.1007/s12032-022-01782-0  0.366
2022 Toi M, Huang CS, Im YH, Sohn J, Zhang W, Sakaguchi S, Haddad N, van Hal G, Sledge GW. Abemaciclib plus fulvestrant in East Asian women with HR+, HER2- advanced breast cancer: Overall Survival from MONARCH 2. Cancer Science. PMID 36168844 DOI: 10.1111/cas.15600  0.349
2022 Aogi K, Watanabe K, Kitada M, Sangai T, Ohtani S, Aruga T, Kawaguchi H, Fujisawa T, Maeda S, Morimoto T, Sato N, Takao S, Morita S, Masuda N, Toi M, et al. Correction to: Clinical usefulness of eribulin as first- or second-line chemotherapy for recurrent HER2-negative breast cancer: a randomized phase II study (JBCRG-19). International Journal of Clinical Oncology. PMID 36166110 DOI: 10.1007/s10147-022-02237-2  0.409
2022 Galactionova K, Loibl S, Salari P, Marmé F, Martin M, Untch M, Bonnefoi HR, Kim SB, Bear HD, McCarthy N, Gelmon KA, García-Sáenz JA, Kelly CM, Reimer T, Toi M, et al. Cost-effectiveness of palbociclib in early breast cancer patients with a high risk of relapse: Results from the PENELOPE-B trial. Frontiers in Oncology. 12: 886831. PMID 36132153 DOI: 10.3389/fonc.2022.886831  0.361
2022 Yamamoto Y, Yamashiro H, Schneeweiss A, Müller V, Gluz O, Klare P, Aktas B, Magdolna D, Büdi L, Pikó B, Mangel L, Toi M, Morita S, Ohno S. Factors affecting prognosis in patients treated with bevacizumab plus paclitaxel as first-line chemotherapy for HER2-negative metastatic breast cancer: an international pooled analysis of individual patient data from four prospective observational studies. Breast Cancer (Tokyo, Japan). PMID 36057014 DOI: 10.1007/s12282-022-01399-1  0.397
2022 Honda M, Iima M, Kataoka M, Fukushima Y, Ota R, Ohashi A, Toi M, Nakamoto Y. Biomarkers Predictive of Distant Disease-free Survival Derived from Diffusion-weighted Imaging of Breast Cancer. Magnetic Resonance in Medical Sciences : Mrms : An Official Journal of Japan Society of Magnetic Resonance in Medicine. PMID 35922924 DOI: 10.2463/mrms.mp.2022-0060  0.375
2022 Velaga R, Tanaka S, Toi M. Molecular vulnerabilities and therapeutic resistance in hormone receptor positive and HER2 dependent breast cancer tumours. Cancer Drug Resistance (Alhambra, Calif.). 5: 487-497. PMID 35800379 DOI: 10.20517/cdr.2022.10  0.45
2022 Yamamoto Y, Iwata H, Taira N, Masuda N, Takahashi M, Yoshinami T, Ueno T, Toyama T, Yamanaka T, Takano T, Kashiwaba M, Tsugawa K, Hasegawa Y, Tamura K, Tada H, ... ... Toi M, et al. Pertuzumab retreatment for HER2-positive advanced breast cancer: a randomized, open-label phase III study (PRECIOUS). Cancer Science. PMID 35754298 DOI: 10.1111/cas.15474  0.414
2022 Paul AM, George B, Saini S, Pillai MR, Toi M, Costa L, Kumar R. Delineation of Pathogenomic Insights of Breast Cancer in Young Women. Cells. 11. PMID 35741056 DOI: 10.3390/cells11121927  0.41
2022 Honda M, Kataoka M, Iima M, Ota R, Ohashi A, Kishimoto AO, Miyake KK, Nickel MD, Yamada Y, Toi M, Nakamoto Y. Visual Evaluation of Ultrafast MRI in the Assessment of Residual Breast Cancer after Neoadjuvant Systemic Therapy: A Preliminary Study Association with Subtype. Tomography (Ann Arbor, Mich.). 8: 1522-1533. PMID 35736873 DOI: 10.3390/tomography8030125  0.415
2022 Kumar R, Abreu C, Toi M, Saini S, Casimiro S, Arora A, Paul AM, Velaga R, Rameshwar P, Lipton A, Gupta S, Costa L. Oncobiology and treatment of breast cancer in young women. Cancer Metastasis Reviews. PMID 35488982 DOI: 10.1007/s10555-022-10034-6  0.438
2022 Ueno T, Kitano S, Masuda N, Ikarashi D, Yamashita M, Chiba T, Kadoya T, Bando H, Yamanaka T, Ohtani S, Nagai S, Nakayama T, Takahashi M, Saji S, Aogi K, ... ... Toi M, et al. Immune microenvironment, homologous recombination deficiency, and therapeutic response to neoadjuvant chemotherapy in triple-negative breast cancer: Japan Breast Cancer Research Group (JBCRG)22 TR. Bmc Medicine. 20: 136. PMID 35462552 DOI: 10.1186/s12916-022-02332-1  0.445
2022 Kikawa Y, Kotake T, Tsuyuki S, Kang Y, Takahara S, Fujimoto Y, Yamashiro H, Yoshibayashi H, Takada M, Yasuoka R, Nakatsukasa K, Yamagami K, Suwa H, Okuno T, Nakayama I, ... ... Toi M, et al. Effectiveness of eribulin as first-line or second-line chemotherapy for HER2-negative hormone-resistant advanced or metastatic breast cancer: findings from the multi-institutional, prospective, observational KBCRN A001: E-SPEC study. Breast Cancer (Tokyo, Japan). PMID 35460066 DOI: 10.1007/s12282-022-01357-x  0.387
2022 Saji S, Taira N, Kitada M, Takano T, Takada M, Ohtake T, Toyama T, Kikawa Y, Hasegawa Y, Fujisawa T, Kashiwaba M, Ishida T, Nakamura R, Yamamoto Y, Toh U, ... ... Toi M, et al. Switch maintenance endocrine therapy plus bevacizumab after bevacizumab plus paclitaxel in advanced or metastatic oestrogen receptor-positive, HER2-negative breast cancer (BOOSTER): a randomised, open-label, phase 2 trial. The Lancet. Oncology. 23: 636-649. PMID 35405087 DOI: 10.1016/S1470-2045(22)00196-6  0.403
2022 Masuda N, Chen Y, Kawaguchi T, Dozono K, Toi M. Safety in Japanese Advanced Breast Cancer Patients Who Received Abemaciclib in MONARCH 2 and MONARCH 3: Assessment of Treatment-Emergent Neutropenia, Diarrhea, and Increased Alanine Aminotransferase and Aspartate Aminotransferase Levels. Cancer Management and Research. 14: 1179-1194. PMID 35342308 DOI: 10.2147/CMAR.S348591  0.406
2022 van Mackelenbergh MT, Seither F, Möbus V, O'Shaughnessy J, Martin M, Joensuu H, Untch M, Nitz U, Steger GG, Miralles JJ, Barrios CH, Toi M, Bear HD, Muss H, Reimer T, et al. Effects of capecitabine as part of neo-/adjuvant chemotherapy - A meta-analysis of individual breast cancer patient data from 13 randomised trials including 15,993 patients. European Journal of Cancer (Oxford, England : 1990). 166: 185-201. PMID 35305453 DOI: 10.1016/j.ejca.2022.02.003  0.359
2022 Kawaguchi H, Yamamoto Y, Saji S, Masuda N, Nakayama T, Aogi K, Anan K, Ito Y, Ohtani S, Sato N, Takano T, Tokunaga E, Nakamura S, Hasegawa Y, Hattori M, ... ... Toi M, et al. Factors associated with overall survival after recurrence in patients with ER-positive/HER2-negative postmenopausal breast cancer: an ad hoc analysis of the JBCRG-C06 Safari study. Japanese Journal of Clinical Oncology. PMID 35296894 DOI: 10.1093/jjco/hyac022  0.352
2022 Tolaney SM, Toi M, Neven P, Sohn J, Grischke EM, Llombart-Cussac A, Soliman H, Wang H, Wijayawardana S, Jansen VM, Litchfield LM, Sledge GW. Clinical Significance of and Mutations in circulating tumor DNA: Analysis from the MONARCH 2 Study of Abemaciclib Plus Fulvestrant. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 35121623 DOI: 10.1158/1078-0432.CCR-21-3276  0.352
2021 Krop IE, Im SA, Barrios C, Bonnefoi H, Gralow J, Toi M, Ellis PA, Gianni L, Swain SM, Im YH, De Laurentiis M, Nowecki Z, Huang CS, Fehrenbacher L, Ito Y, et al. Trastuzumab Emtansine Plus Pertuzumab Versus Taxane Plus Trastuzumab Plus Pertuzumab After Anthracycline for High-Risk Human Epidermal Growth Factor Receptor 2-Positive Early Breast Cancer: The Phase III KAITLIN Study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2100896. PMID 34890214 DOI: 10.1200/JCO.21.00896  0.378
2021 Masuda N, Kosaka N, Iwata H, Toi M. Palbociclib as an early-line treatment for Japanese patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: a review of clinical trial and real-world data. International Journal of Clinical Oncology. 26: 2179-2193. PMID 34698970 DOI: 10.1007/s10147-021-02013-8  0.426
2021 Yotsumoto D, Sagara Y, Kumamaru H, Niikura N, Miyata H, Kanbayashi C, Tsuda H, Yamamoto Y, Aogi K, Kubo M, Tamura K, Hayashi N, Miyashita M, Kadoya T, Saji S, ... Toi M, et al. Trends in adjuvant therapy after breast-conserving surgery for ductal carcinoma in situ of breast: a retrospective cohort study using the National Breast Cancer Registry of Japan. Breast Cancer (Tokyo, Japan). PMID 34665435 DOI: 10.1007/s12282-021-01307-z  0.396
2021 Takahashi M, Tokunaga E, Mori J, Tanizawa Y, van der Walt JS, Kawaguchi T, Goetz MP, Toi M. Japanese subgroup analysis of the phase 3 MONARCH 3 study of abemaciclib as initial therapy for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer. Breast Cancer (Tokyo, Japan). PMID 34661821 DOI: 10.1007/s12282-021-01295-0  0.393
2021 Fukada I, Ito Y, Kondo N, Ohtani S, Hattori M, Tokunaga E, Matsunami N, Mashino K, Kosaka T, Tanabe M, Yotsumoto D, Yamanouchi K, Sawaki M, Kashiwaba M, Kawabata H, ... ... Toi M, et al. A phase II study of sequential treatment with anthracycline and taxane followed by eribulin in patients with HER2-negative, locally advanced breast cancer (JBCRG-17). Breast Cancer Research and Treatment. PMID 34554370 DOI: 10.1007/s10549-021-06396-0  0.398
2021 Neven P, Rugo HS, Tolaney SM, Iwata H, Toi M, Goetz MP, Kaufman PA, Lu Y, Haddad N, Hurt KC, Sledge GW. Abemaciclib plus fulvestrant in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in premenopausal women: subgroup analysis from the MONARCH 2 trial. Breast Cancer Research : Bcr. 23: 87. PMID 34425869 DOI: 10.1186/s13058-021-01463-2  0.308
2021 Neven P, Johnston SRD, Toi M, Sohn J, Inoue K, Pivot X, Burdaeva O, Okera M, Masuda N, Kaufman PA, Koh H, Grischke EM, Conte P, Lu Y, Haddad N, et al. MONARCH 2: subgroup analysis of patients receiving abemaciclib plus fulvestrant as first-line and second-line therapy for HR+, HER2- advanced breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34376533 DOI: 10.1158/1078-0432.CCR-20-4685  0.363
2021 Miyake KK, Kataoka M, Ishimori T, Matsumoto Y, Torii M, Takada M, Satoh Y, Kubota K, Satake H, Yakami M, Isoda H, Ikeda DM, Toi M, Nakamoto Y. A Proposed Dedicated Breast PET Lexicon: Standardization of Description and Reporting of Radiotracer Uptake in the Breast. Diagnostics (Basel, Switzerland). 11. PMID 34359350 DOI: 10.3390/diagnostics11071267  0.369
2021 Aogi K, Watanabe K, Kitada M, Sangai T, Ohtani S, Aruga T, Kawagichi H, Fujisawa T, Maeda S, Morimoto T, Sato N, Takao S, Morita S, Masuda N, Toi M, et al. Correction to: Clinical usefulness of eribulin as first- or second-line chemotherapy for recurrent HER2-negative breast cancer: a randomized phase II study (JBCRG-19). International Journal of Clinical Oncology. PMID 34043103 DOI: 10.1007/s10147-021-01940-w  0.409
2021 Senda N, Kawaguchi-Sakita N, Kawashima M, Inagaki-Kawata Y, Yoshida K, Takada M, Kataoka M, Torii M, Nishimura T, Kawaguchi K, Suzuki E, Kataoka Y, Matsumoto Y, Yoshibayashi H, Yamagami K, ... ... Toi M, et al. Optimization of prediction methods for risk assessment of pathogenic germline variants in the Japanese population. Cancer Science. PMID 34036661 DOI: 10.1111/cas.14986  0.389
2021 Itou J, Nakamura A, Hokazono H, Toi M. Supplementation with Fermented Barley Extract Prevents Mammary Epithelial Cell Invasion in an Early Breast Cancer Model. Acta Histochemica Et Cytochemica. 54: 73-78. PMID 34012179 DOI: JST.JSTAGE/ahc/20-00029  0.443
2021 Aogi K, Watanabe K, Kitada M, Sangai T, Ohtani S, Aruga T, Kawagichi H, Fujisawa T, Maeda S, Morimoto T, Sato N, Takao S, Morita S, Masuda N, Toi M, et al. Clinical usefulness of eribulin as first- or second-line chemotherapy for recurrent HER2-negative breast cancer: a randomized phase II study (JBCRG-19). International Journal of Clinical Oncology. 26: 1229-1236. PMID 33891194 DOI: 10.1007/s10147-021-01920-0  0.411
2021 Inoue K, Masuda N, Iwata H, Takahashi M, Ito Y, Miyoshi Y, Nakayama T, Mukai H, van der Walt JS, Mori J, Sakaguchi S, Kawaguchi T, Tanizawa Y, Llombart-Cussac A, Sledge GW, ... Toi M, et al. Japanese subpopulation analysis of MONARCH 2: phase 3 study of abemaciclib plus fulvestrant for treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer that progressed on endocrine therapy. Breast Cancer (Tokyo, Japan). PMID 33797023 DOI: 10.1007/s12282-021-01239-8  0.329
2021 Loibl S, Marmé F, Martin M, Untch M, Bonnefoi H, Kim SB, Bear H, McCarthy N, Melé Olivé M, Gelmon K, García-Sáenz J, Kelly CM, Reimer T, Toi M, Rugo HS, et al. Palbociclib for Residual High-Risk Invasive HR-Positive and HER2-Negative Early Breast Cancer-The Penelope-B Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2003639. PMID 33793299 DOI: 10.1200/JCO.20.03639  0.405
2021 Masuda N, Bando H, Yamanaka T, Kadoya T, Takahashi M, Nagai SE, Ohtani S, Aruga T, Suzuki E, Kikawa Y, Yasojima H, Kasai H, Ishiguro H, Kawabata H, Morita S, ... ... Toi M, et al. Eribulin-based neoadjuvant chemotherapy for triple-negative breast cancer patients stratified by homologous recombination deficiency status: a multicenter randomized phase II clinical trial. Breast Cancer Research and Treatment. PMID 33763789 DOI: 10.1007/s10549-021-06184-w  0.447
2021 Piccart M, Procter M, Fumagalli D, de Azambuja E, Clark E, Ewer MS, Restuccia E, Jerusalem G, Dent S, Reaby L, Bonnefoi H, Krop I, Liu TW, Pieńkowski T, Toi M, et al. Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer in the APHINITY Trial: 6 Years' Follow-Up. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2001204. PMID 33539215 DOI: 10.1200/JCO.20.01204  0.356
2021 Goetz MP, Okera M, Wildiers H, Campone M, Grischke EM, Manso L, André VAM, Chouaki N, San Antonio B, Toi M, Sledge GW. Safety and efficacy of abemaciclib plus endocrine therapy in older patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: an age-specific subgroup analysis of MONARCH 2 and 3 trials. Breast Cancer Research and Treatment. PMID 33392835 DOI: 10.1007/s10549-020-06029-y  0.323
2021 Toi M, Imoto S, Ishida T, Ito Y, Iwata H, Masuda N, Mukai H, Saji S, Shimizu A, Ikeda T, Haga H, Saeki T, Aogi K, Sugie T, Ueno T, et al. Adjuvant S-1 plus endocrine therapy for oestrogen receptor-positive, HER2-negative, primary breast cancer: a multicentre, open-label, randomised, controlled, phase 3 trial. The Lancet. Oncology. 22: 74-84. PMID 33387497 DOI: 10.1016/S1470-2045(20)30534-9  0.457
2020 Masuda N, Mukai H, Inoue K, Rai Y, Ohno S, Ohtani S, Shimizu C, Hashigaki S, Muramatsu Y, Umeyama Y, Iwata H, Toi M. Analysis of subsequent therapy in Japanese patients with hormone receptor‒positive/human epidermal growth factor receptor 2‒negative advanced breast cancer who received palbociclib plus endocrine therapy in PALOMA-2 and -3. Breast Cancer (Tokyo, Japan). PMID 33085032 DOI: 10.1007/s12282-020-01162-4  0.33
2020 Inagaki-Kawata Y, Yoshida K, Kawaguchi-Sakita N, Kawashima M, Nishimura T, Senda N, Shiozawa Y, Takeuchi Y, Inoue Y, Sato-Otsubo A, Fujii Y, Nannya Y, Suzuki E, Takada M, Tanaka H, ... ... Toi M, et al. Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants. Communications Biology. 3: 578. PMID 33067557 DOI: 10.1038/s42003-020-01301-9  0.358
2020 Johnston SRD, Harbeck N, Hegg R, Toi M, Martin M, Shao ZM, Zhang QY, Martinez Rodriguez JL, Campone M, Hamilton E, Sohn J, Guarneri V, Okada M, Boyle F, Neven P, et al. Abemaciclib Combined With Endocrine Therapy for the Adjuvant Treatment of HR+, HER2-, Node-Positive, High-Risk, Early Breast Cancer (monarchE). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2002514. PMID 32954927 DOI: 10.1200/JCO.20.02514  0.413
2020 Kawashima M, Bensaad K, Zois CE, Barberis A, Bridges E, Wigfield S, Lagerholm C, Dmitriev RI, Tokiwa M, Toi M, Papkovsky DB, Buffa FM, Harris AL. Correction to: Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells. Cancer & Metabolism. 8: 18. PMID 32789015 DOI: 10.1186/s40170-020-00224-7  0.645
2020 Yamamoto Y, Yamashiro H, Toh U, Kondo N, Nakamura R, Kashiwaba M, Takahashi M, Tsugawa K, Ishikawa T, Nakayama T, Ohtani S, Takano T, Fujisawa T, Toyama T, Kawaguchi H, ... ... Toi M, et al. Prospective observational study of bevacizumab combined with paclitaxel as first- or second-line chemotherapy for locally advanced or metastatic breast cancer: the JBCRG-C05 (B-SHARE) study. Breast Cancer (Tokyo, Japan). PMID 32715420 DOI: 10.1007/s12282-020-01138-4  0.415
2020 Kawashima M, Bensaad K, Zois CE, Barberis A, Bridges E, Wigfield S, Lagerholm C, Dmitriev RI, Tokiwa M, Toi M, Papkovsky DB, Buffa FM, Harris AL. Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells. Cancer & Metabolism. 8: 13. PMID 32647572 DOI: 10.1186/S40170-020-00219-4  0.642
2020 Chow LWC, Lie EF, Toi M. Advances in EGFR/HER2-directed clinical research on breast cancer. Advances in Cancer Research. 147: 375-428. PMID 32593406 DOI: 10.1016/bs.acr.2020.04.009  0.429
2020 Lin X, Matsumoto Y, Nakakimura T, Ono K, Umeoka S, Torii M, Yoshibayashi H, Toi M. Invasive solid papillary carcinoma with neuroendocrine differentiation of the breast: a case report and literature review. Surgical Case Reports. 6: 143. PMID 32562013 DOI: 10.1186/s40792-020-00905-x  0.413
2020 Goetz MP, Martin M, Tokunaga E, Park IH, Huober J, Toi M, Stoffregen C, Shekarriz S, Andre V, Gainford MC, Price GL, Johnston S. Health-Related Quality of Life in MONARCH 3: Abemaciclib Plus an Aromatase Inhibitor as Initial Therapy in HR+, HER2- Advanced Breast Cancer. The Oncologist. PMID 32536013 DOI: 10.1634/theoncologist.2020-0084  0.333
2020 Takada M, Toi M. Neoadjuvant treatment for HER2-positive breast cancer. Chinese Clinical Oncology. 9: 32. PMID 32527117 DOI: 10.21037/cco-20-123  0.361
2020 Takahashi M, Masuda N, Nishimura R, Inoue K, Ohno S, Iwata H, Hashigaki S, Muramatsu Y, Umeyama Y, Toi M. Palbociclib-letrozole as first-line treatment for advanced breast cancer: Updated results from a Japanese phase 2 study. Cancer Medicine. PMID 32420697 DOI: 10.1002/cam4.3091  0.346
2020 Tanaka S, Ishii T, Sato F, Toi M, Itou J. Eribulin mesylate-induced c-Fos upregulation enhances cell survival in breast cancer cell lines. Biochemical and Biophysical Research Communications. PMID 32201082 DOI: 10.1016/j.bbrc.2020.03.042  0.353
2020 Ishiguro H, Masuda N, Sato N, Higaki K, Morimoto T, Yanagita Y, Mizutani M, Ohtani S, Kaneko K, Fujisawa T, Takahashi M, Kadoya T, Matsunami N, Yamamoto Y, Ohno S, ... ... Toi M, et al. A randomized study comparing docetaxel/cyclophosphamide (TC), 5-fluorouracil/epirubicin/cyclophosphamide (FEC) followed by TC, and TC followed by FEC for patients with hormone receptor-positive HER2-negative primary breast cancer. Breast Cancer Research and Treatment. PMID 32170634 DOI: 10.1007/s10549-020-05590-w  0.311
2020 Yamashiro H, Iwata H, Masuda N, Yamamoto N, Nishimura R, Ohtani S, Sato N, Takahashi M, Kamio T, Yamazaki K, Saito T, Kato M, Lee T, Kuroi K, Takano T, ... ... Toi M, et al. Outcomes of trastuzumab therapy in HER2-positive early breast cancer patients: extended follow-up of JBCRG-cohort study 01. Breast Cancer (Tokyo, Japan). PMID 32060785 DOI: 10.1007/S12282-020-01057-4  0.373
2020 Kaufman PA, Toi M, Neven P, Sohn J, Grischke EM, Andre V, Stoffregen C, Shekarriz S, Price GL, Carter GC, Sledge GW. Health-Related Quality of Life in MONARCH 2: Abemaciclib plus Fulvestrant in Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer After Endocrine Therapy. The Oncologist. 25: e243-e251. PMID 32043763 DOI: 10.1634/theoncologist.2019-0551  0.323
2020 Itou J, Takahashi R, Sasanuma H, Tsuda M, Morimoto S, Matsumoto Y, Ishii T, Sato F, Takeda S, Toi M. Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition. Iscience. 23: 100821. PMID 31978754 DOI: 10.1016/j.isci.2020.100821  0.402
2020 Masuda N, Ohtani S, Takano T, Inoue K, Suzuki E, Nakamura R, Bando H, Ito Y, Ishida K, Yamanaka T, Kuroi K, Yasojima H, Kasai H, Takasuka T, Sakurai T, ... ... Toi M, et al. A randomized, 3-arm, neoadjuvant, phase 2 study comparing docetaxel + carboplatin + trastuzumab + pertuzumab (TCbHP), TCbHP followed by trastuzumab emtansine and pertuzumab (T-DM1+P), and T-DM1+P in HER2-positive primary breast cancer. Breast Cancer Research and Treatment. PMID 31953696 DOI: 10.1007/s10549-020-05524-6  0.383
2020 Ueno T, Masuda N, Sato N, Ohtani S, Yamamura J, Matsunami N, Kashiwaba M, Takano T, Takahashi M, Kaneko K, Ohno S, Morita S, Toi M. Multicenter study of primary systemic therapy with docetaxel, cyclophosphamide and trastuzumab for HER2-positive operable breast cancer: the JBCRG-10 study. Japanese Journal of Clinical Oncology. 50: 3-11. PMID 31821506 DOI: 10.1093/jjco/hyz119  0.308
2020 Honda M, Kataoka M, Onishi N, Iima M, Ohashi A, Kanao S, Nickel MD, Toi M, Togashi K. New parameters of ultrafast dynamic contrast-enhanced breast MRI using compressed sensing. Journal of Magnetic Resonance Imaging : Jmri. 51: 164-174. PMID 31215107 DOI: 10.1002/jmri.26838  0.346
2019 Shibata T, Watari K, Kawahara A, Sudo T, Hattori S, Murakami Y, Izumi H, Itou J, Toi M, Akiba J, Akagi Y, Tanaka M, Kuwano M, Ono M. Targeting phosphorylation of Y-box binding protein YBX1 by TAS0612 and everolimus in overcoming antiestrogen resistance. Molecular Cancer Therapeutics. PMID 31879363 DOI: 10.1158/1535-7163.MCT-19-0690  0.395
2019 Kawashima M, Tokiwa M, Nishimura T, Kawata Y, Sugimoto M, Kataoka TR, Sakurai T, Iwaisako K, Suzuki E, Hagiwara M, Harris AL, Toi M. High-resolution imaging mass spectrometry combined with transcriptomic analysis identified a link between fatty acid composition of phosphatidylinositols and the immune checkpoint pathway at the primary tumour site of breast cancer. British Journal of Cancer. PMID 31819188 DOI: 10.1038/s41416-019-0662-8  0.516
2019 Kawaguchi H, Masuda N, Nakayama T, Aogi K, Anan K, Ito Y, Ohtani S, Sato N, Saji S, Takano T, Tokunaga E, Nakamura S, Hasegawa Y, Hattori M, Fujisawa T, ... ... Toi M, et al. Factors associated with prolonged overall survival in patients with postmenopausal estrogen receptor-positive advanced breast cancer using real-world data: a follow-up analysis of the JBCRG-C06 Safari study. Breast Cancer (Tokyo, Japan). PMID 31811519 DOI: 10.1007/s12282-019-01029-3  0.328
2019 Sledge GW, Toi M, Neven P, Sohn J, Inoue K, Pivot X, Burdaeva O, Okera M, Masuda N, Kaufman PA, Koh H, Grischke EM, Conte P, Lu Y, Barriga S, et al. The Effect of Abemaciclib Plus Fulvestrant on Overall Survival in Hormone Receptor-Positive, ERBB2-Negative Breast Cancer That Progressed on Endocrine Therapy-MONARCH 2: A Randomized Clinical Trial. Jama Oncology. PMID 31563959 DOI: 10.1001/jamaoncol.2019.4782  0.376
2019 Perez EA, Barrios C, Eiermann W, Toi M, Im YH, Conte P, Martin M, Pienkowski T, Pivot XB, Burris HA, Petersen JA, De Haas S, Hoersch S, Patre M, Ellis PA. Trastuzumab emtansine with or without pertuzumab versus trastuzumab with taxane for human epidermal growth factor receptor 2-positive advanced breast cancer: Final results from MARIANNE. Cancer. PMID 31318460 DOI: 10.1002/cncr.32392  0.362
2019 Tanaka S, Senda N, Iida A, Sehara-Fujisawa A, Ishii T, Sato F, Toi M, Itou J. In silico analysis-based identification of the target residue of integrin α6 for metastasis inhibition of basal-like breast cancer. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 31295752 DOI: 10.1111/gtc.12714  0.334
2019 Ono Y, Yoshimura M, Hirata K, Yamauchi C, Toi M, Suzuki E, Takada M, Hiraoka M, Mizowaki T. The impact of age on the risk of ipsilateral breast tumor recurrence after breast-conserving therapy in breast cancer patients with a > 5 mm margin treated without boost irradiation. Radiation Oncology (London, England). 14: 121. PMID 31291997 DOI: 10.1186/s13014-019-1327-8  0.353
2019 Perez EA, de Haas SL, Eiermann W, Barrios CH, Toi M, Im YH, Conte PF, Martin M, Pienkowski T, Pivot XB, Burris HA, Stanzel S, Patre M, Ellis PA. Correction to: Relationship between tumor biomarkers and efficacy in MARIANNE, a phase III study of trastuzumab emtansine ± pertuzumab versus trastuzumab plus taxane in HER2-positive advanced breast cancer. Bmc Cancer. 19: 620. PMID 31234810 DOI: 10.1186/s12885-019-5831-x  0.345
2019 Masuda N, Mukai H, Inoue K, Rai Y, Ohno S, Mori Y, Hashigaki S, Muramatsu Y, Umeyama Y, Iwata H, Toi M. Correction to: Neutropenia management with palbociclib in Japanese patients with advanced breast cancer. Breast Cancer (Tokyo, Japan). PMID 31168692 DOI: 10.1007/s12282-019-00984-1  0.416
2019 Perez EA, de Haas SL, Eiermann W, Barrios CH, Toi M, Im YH, Conte PF, Martin M, Pienkowski T, Pivot XB, Burris HA, Stanzel S, Patre M, Ellis PA. Relationship between tumor biomarkers and efficacy in MARIANNE, a phase III study of trastuzumab emtansine ± pertuzumab versus trastuzumab plus taxane in HER2-positive advanced breast cancer. Bmc Cancer. 19: 517. PMID 31146717 DOI: 10.1186/s12885-019-5687-0  0.332
2019 Masuda N, Mukai H, Inoue K, Rai Y, Ohno S, Mori Y, Hashigaki S, Muramatsu Y, Umeyama Y, Iwata H, Toi M. Neutropenia management with palbociclib in Japanese patients with advanced breast cancer. Breast Cancer (Tokyo, Japan). PMID 31127500 DOI: 10.1007/s12282-019-00970-7  0.348
2019 Im SA, Mukai H, Park IH, Masuda N, Shimizu C, Kim SB, Im YH, Ohtani S, Huang Bartlett C, Lu DR, Iyer S, Mori Y, Mori A, Gauthier E, Finn RS, ... Toi M, et al. Palbociclib Plus Letrozole as First-Line Therapy in Postmenopausal Asian Women With Metastatic Breast Cancer: Results From the Phase III, Randomized PALOMA-2 Study. Journal of Global Oncology. 1-19. PMID 31125276 DOI: 10.1200/JGO.18.00173  0.416
2019 Sakaguchi R, Kataoka M, Kanao S, Miyake KK, Nakamoto Y, Sugie T, Toi M, Mikami Y, Togashi K. Distribution pattern of FDG uptake using ring-type dedicated breast PET in comparison to whole-body PET/CT scanning in invasive breast cancer. Annals of Nuclear Medicine. PMID 31115856 DOI: 10.1007/s12149-019-01364-7  0.342
2019 Yap YS, Lu YS, Tamura K, Lee JE, Ko EY, Park YH, Cao AY, Lin CH, Toi M, Wu J, Lee SC. Insights Into Breast Cancer in the East vs the West: A Review. Jama Oncology. PMID 31095268 DOI: 10.1001/jamaoncol.2019.0620  0.428
2019 Takada M, Toi M. Cryosurgery for primary breast cancers, its biological impact, and clinical outcomes. International Journal of Clinical Oncology. 24: 608-613. PMID 30982153 DOI: 10.1007/s10147-019-01448-4  0.481
2019 Ueno T, Saji S, Masuda N, Iwata H, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Sasano H, Toi M. Changes in Recurrence Score by neoadjuvant endocrine therapy of breast cancer and their prognostic implication. Esmo Open. 4: e000476. PMID 30962956 DOI: 10.1136/esmoopen-2018-000476  0.397
2019 Benson JR, Jatoi I, Toi M. Surgical management of multiple ipsilateral breast cancers. Future Oncology (London, England). PMID 30924355 DOI: 10.2217/fon-2019-0028  0.425
2019 Ueno T, Masuda N, Kamigaki S, Morimoto T, Saji S, Imoto S, Sasano H, Toi M. Differential Involvement of Autophagy and Apoptosis in Response to Chemoendocrine and Endocrine Therapy in Breast Cancer: JBCRG-07TR. International Journal of Molecular Sciences. 20. PMID 30813476 DOI: 10.3390/ijms20040984  0.311
2019 Kikawa Y, Kotake T, Kajiwara Y, Hashimoto K, Yamashiro H, Ohtani S, Takao S, Toi M. Clinical Predictive Factors for the Efficacy of Everolimus in Patients With Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer: A Multicenter Retrospective Cohort Study in Japan. Breast Cancer : Basic and Clinical Research. 13: 1178223418825135. PMID 30733627 DOI: 10.1177/1178223418825135  0.426
2018 Ueno T, Saji S, Chiba T, Kamma H, Isaka H, Itoh H, Imi K, Miyamoto K, Tada M, Sasano H, Toi M, Imoto S. Progesterone receptor expression in proliferating cancer cells of hormone-receptor-positive breast cancer. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 40: 1010428318811025. PMID 30841783 DOI: 10.1177/1010428318811025  0.321
2018 Shibata T, Tokunaga E, Hattori S, Watari K, Murakami Y, Yamashita N, Oki E, Itou J, Toi M, Maehara Y, Kuwano M, Ono M. Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer. Oncotarget. 9: 37216-37228. PMID 30647855 DOI: 10.18632/oncotarget.26469  0.364
2018 Shiina T, Toi M, Yagi T. Development and clinical translation of photoacoustic mammography. Biomedical Engineering Letters. 8: 157-165. PMID 30603200 DOI: 10.1007/s13534-018-0070-7  0.358
2018 Mukai H, Shimizu C, Masuda N, Ohtani S, Ohno S, Takahashi M, Yamamoto Y, Nishimura R, Sato N, Ohsumi S, Iwata H, Mori Y, Hashigaki S, Muramatsu Y, Nagasawa T, ... ... Toi M, et al. Palbociclib in combination with letrozole in patients with estrogen receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: PALOMA-2 subgroup analysis of Japanese patients. International Journal of Clinical Oncology. PMID 30515674 DOI: 10.1007/s10147-018-1353-9  0.33
2018 Sasanuma H, Tsuda M, Morimoto S, Saha LK, Rahman MM, Kiyooka Y, Fujiike H, Cherniack AD, Itou J, Callen Moreu E, Toi M, Nakada S, Tanaka H, Tsutsui K, Yamada S, et al. BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes. Proceedings of the National Academy of Sciences of the United States of America. PMID 30352856 DOI: 10.1073/Pnas.1803177115  0.371
2018 Suzuki E, Sugimoto M, Kawaguchi K, Pu F, Uozumi R, Yamaguchi A, Nishie M, Tsuda M, Kotake T, Morita S, Toi M. Gene expression profile of peripheral blood mononuclear cells may contribute to the identification and immunological classification of breast cancer patients. Breast Cancer (Tokyo, Japan). PMID 30317464 DOI: 10.1007/s12282-018-0920-2  0.37
2018 Takada M, Sugimoto M, Masuda N, Iwata H, Kuroi K, Yamashiro H, Ohno S, Ishiguro H, Inamoto T, Toi M. Prediction of postoperative disease-free survival and brain metastasis for HER2-positive breast cancer patients treated with neoadjuvant chemotherapy plus trastuzumab using a machine learning algorithm. Breast Cancer Research and Treatment. 172: 611-618. PMID 30194511 DOI: 10.1007/s10549-018-4958-9  0.393
2018 Yamamoto Y, Iwata H, Ueno T, Taira N, Kashiwaba M, Takahashi M, Tada H, Tsugawa K, Toyama T, Niikura N, Hara F, Fujisawa T, Yoshinami T, Saji S, Takano T, ... ... Toi M, et al. A randomized, open-label, Phase III trial of pertuzumab retreatment in HER2-positive locally advanced/metastatic breast cancer patients previously treated with pertuzumab, trastuzumab and chemotherapy: the Japan Breast Cancer Research Group-M05 PRECIOUS study. Japanese Journal of Clinical Oncology. PMID 30020510 DOI: 10.1093/jjco/hyy097  0.361
2018 Yamashiro H, Sawaki M, Masuda N, Okumura Y, Takano T, Tokunaga E, Saito T, Sagara Y, Yamazaki K, Kawaguchi Y, Lee T, Ozaki S, Yamagami K, Yamamoto N, Kuroi K, ... ... Toi M, et al. Survival Outcomes of Retreatment with Trastuzumab and Cytotoxic Chemotherapy for HER2-Positive Recurrent Patients With Breast Cancer Who Had Been Treated with Neo/adjuvant Trastuzumab Plus Multidrug Chemotherapy: A Japanese Multicenter Observational Study. Breast Cancer : Basic and Clinical Research. 12: 1178223418786243. PMID 30013356 DOI: 10.1177/1178223418786243  0.428
2018 Yamaga I, Kawaguchi-Sakita N, Asao Y, Matsumoto Y, Yoshikawa A, Fukui T, Takada M, Kataoka M, Kawashima M, Fakhrejahani E, Kanao S, Nakayama Y, Tokiwa M, Torii M, Yagi T, ... ... Toi M, et al. Vascular branching point counts using photoacoustic imaging in the superficial layer of the breast: A potential biomarker for breast cancer. Photoacoustics. 11: 6-13. PMID 30003041 DOI: 10.1016/j.pacs.2018.06.002  0.483
2018 Kiso M, Tanaka S, Saji S, Toi M, Sato F. Long isoform of VEGF stimulates cell migration of breast cancer by filopodia formation via NRP1/ARHGAP17/Cdc42 regulatory network. International Journal of Cancer. PMID 29971782 DOI: 10.1002/ijc.31645  0.395
2018 Sagara Y, Takada M, Ohi Y, Ohtani S, Kurozumi S, Inoue K, Kosaka Y, Hattori M, Yamashita T, Takao S, Sato N, Iwata H, Kurosumi M, Toi M. Effectiveness of neo-adjuvant systemic therapy with trastuzumab for basal HER2 type breast cancer: results from retrospective cohort study of Japan Breast Cancer Research Group (JBCRG)-C03. Breast Cancer Research and Treatment. PMID 29971625 DOI: 10.1007/s10549-018-4873-0  0.487
2018 Sato N, Masuda N, Morimoto T, Ueno T, Kanbayashi C, Kaneko K, Yasojima H, Saji S, Sasano H, Morita S, Ohno S, Toi M. Neoadjuvant endocrine therapy with exemestane followed by response-guided combination therapy with low-dose cyclophosphamide in postmenopausal patients with estrogen receptor-positive breast cancer: A multicenter, open-label, phase II study. Cancer Medicine. PMID 29905023 DOI: 10.1002/cam4.1600  0.368
2018 Ueno T, Masuda N, Kamigaki S, Morimoto T, Akiyama F, Kurosumi M, Tsuda H, Mikami Y, Tanaka S, Morita S, Toi M. A multicenter phase II trial of neoadjuvant letrozole plus low-dose cyclophosphamide in postmenopausal patients with estrogen receptor-positive breast cancer (JBCRG-07): therapeutic efficacy and clinical implications of circulating endothelial cells. Cancer Medicine. PMID 29733541 DOI: 10.1002/cam4.1516  0.379
2018 Bidard FC, Michiels S, Riethdorf S, Mueller V, Esserman LJ, Lucci A, Naume B, Horiguchi J, Gisbert-Criado R, Sleijfer S, Toi M, Garcia-Saenz JA, Hartkopf A, Generali D, Rothé F, et al. Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis. Journal of the National Cancer Institute. PMID 29659933 DOI: 10.1093/Jnci/Djy018  0.599
2018 Miyake O, Murata K, Tanaka S, Ishiguro H, Toi M, Tamura K, Kawakami K. Costs associated with febrile neutropenia in Japanese patients with primary breast cancer: post-hoc analysis of a randomized clinical trial. Japanese Journal of Clinical Oncology. 48: 410-416. PMID 29590407 DOI: 10.1093/jjco/hyy030  0.381
2018 Ueno T, Saji S, Masuda N, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Yamanaka T, Sasano H, Toi M. Impact of clinical response to neoadjuvant endocrine therapy on patient outcomes: a follow-up study of JFMC34-0601 multicentre prospective neoadjuvant endocrine trial. Esmo Open. 3: e000314. PMID 29531841 DOI: 10.1136/esmoopen-2017-000314  0.354
2018 Filipits M, Dafni U, Gnant M, Polydoropoulou V, Hills M, Kiermaier A, de Azambuja E, Larsimont D, Rojo F, Viale G, Toi M, Harbeck N, Prichard KI, Gelber RD, Dinh P, et al. Association of p27 and Cyclin D1 Expression and Benefit from Adjuvant Trastuzumab Treatment in HER2-Positive Early Breast Cancer: A TransHERA Study. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 24: 3079-3086. PMID 29530933 DOI: 10.1158/1078-0432.CCR-17-3473  0.306
2018 Kotake T, Toi M. Abemaciclib for the treatment of breast cancer. Expert Opinion On Pharmacotherapy. 19: 517-524. PMID 29522364 DOI: 10.1080/14656566.2018.1448787  0.461
2018 Itou J, Li W, Ito S, Tanaka S, Matsumoto Y, Sato F, Toi M. Sal-like 4 protein levels in breast cancer cells are post-translationally down-regulated by tripartite motif containing 21. The Journal of Biological Chemistry. PMID 29511085 DOI: 10.1074/jbc.RA117.000245  0.433
2018 Förnvik D, Kataoka M, Iima M, Ohashi A, Kanao S, Toi M, Togashi K. The role of breast tomosynthesis in a predominantly dense breast population at a tertiary breast centre: breast density assessment and diagnostic performance in comparison with MRI. European Radiology. 28: 3194-3203. PMID 29460074 DOI: 10.1007/s00330-017-5297-7  0.401
2018 Miyake KK, Nakamoto Y, Saji S, Sugie T, Kurihara K, Kanao S, Ikeda DM, Toi M, Togashi K. Impact of physiological hormonal fluctuations on F-fluorodeoxyglucose uptake in breast cancer. Breast Cancer Research and Treatment. 169: 437-446. PMID 29423901 DOI: 10.1007/s10549-018-4711-4  0.32
2018 Itou J, Tsukihara H, Nukatsuka M, Toi M, Takechi T. 5-Chloro-2,4-dihydroxypyridine, CDHP, prevents lung metastasis of basal-like breast cancer cells by reducing nascent adhesion formation. Cancer Medicine. 7: 463-470. PMID 29356434 DOI: 10.1002/cam4.1265  0.316
2018 Matsumoto Y, Itou J, Sato F, Toi M. SALL4 - KHDRBS3 network enhances stemness by modulating CD44 splicing in basal-like breast cancer. Cancer Medicine. PMID 29356399 DOI: 10.1002/cam4.1296  0.404
2018 Sugie T, Suzuki E, Yamauchi A, Yamagami K, Masuda N, Gondo N, Sumi E, Ikeda T, Tada H, Uozumi R, Kanao S, Tanaka Y, Hamazaki Y, Minato N, Toi M. Combined effects of neoadjuvant letrozole and zoledronic acid on γδT cells in postmenopausal women with early-stage breast cancer. Breast (Edinburgh, Scotland). 38: 114-119. PMID 29310035 DOI: 10.1016/j.breast.2017.12.017  0.483
2017 Tanaka S, Ueno T, Ishiguro H, Morita S, Toi M. The lack of increases in circulating endothelial progenitor cell as a negative predictor for pathological response to neoadjuvant chemotherapy in breast cancer patients. Npj Precision Oncology. 1: 6. PMID 29872695 DOI: 10.1038/s41698-017-0006-1  0.332
2017 Toi M, Masuda N, Lee SJ. Capecitabine for primary breast cancer. Oncotarget. 8: 110739-110740. PMID 29340011 DOI: 10.18632/oncotarget.22990  0.502
2017 Chow LW, Morita S, Chow CY, Ng WK, Toi M. Neoadjuvant palbociclib on ER+ breast cancer (N007): clinical response and EndoPredict value. Endocrine-Related Cancer. PMID 29158285 DOI: 10.1530/ERC-17-0396  0.308
2017 Kawaguchi H, Masuda N, Nakayama T, Aogi K, Anan K, Ito Y, Ohtani S, Sato N, Saji S, Takano T, Tokunaga E, Nakamura S, Hasegawa Y, Hattori M, Fujisawa T, ... ... Toi M, et al. Factors associated with prolonged time to treatment failure with fulvestrant 500 mg in patients with postmenopausal estrogen receptor-positive advanced breast cancer: a subgroup analysis of the JBCRG-C06 Safari study. Current Medical Research and Opinion. 1-16. PMID 29095648 DOI: 10.1080/03007995.2017.1400426  0.332
2017 Goetz MP, Toi M, Campone M, Sohn J, Paluch-Shimon S, Huober J, Park IH, Trédan O, Chen SC, Manso L, Freedman OC, Garnica Jaliffe G, Forrester T, Frenzel M, Barriga S, et al. MONARCH 3: Abemaciclib As Initial Therapy for Advanced Breast Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017756155. PMID 28968163 DOI: 10.1200/JCO.2017.75.6155  0.343
2017 Sagara Y, Julia W, Golshan M, Toi M. Paradigm Shift toward Reducing Overtreatment of Ductal Carcinoma of Breast. Frontiers in Oncology. 7: 192. PMID 28894698 DOI: 10.3389/fonc.2017.00192  0.402
2017 Toi M, Masuda N, Ohashi Y. Adjuvant Capecitabine for Breast Cancer. The New England Journal of Medicine. 377: 791-2. PMID 28834474 DOI: 10.1056/NEJMc1708487  0.513
2017 Masuda N, Lee SJ, Ohtani S, Im YH, Lee ES, Yokota I, Kuroi K, Im SA, Park BW, Kim SB, Yanagita Y, Ohno S, Takao S, Aogi K, Iwata H, ... ... Toi M, et al. Adjuvant Capecitabine for Breast Cancer after Preoperative Chemotherapy. The New England Journal of Medicine. 376: 2147-2159. PMID 28564564 DOI: 10.1056/NEJMoa1612645  0.36
2017 Onishi N, Kataoka M, Kanao S, Sagawa H, Iima M, Nickel MD, Toi M, Togashi K. Ultrafast dynamic contrast-enhanced mri of the breast using compressed sensing: breast cancer diagnosis based on separate visualization of breast arteries and veins. Journal of Magnetic Resonance Imaging : Jmri. 47: 97-104. PMID 28556576 DOI: 10.1002/jmri.25747  0.409
2017 Toi M, Shao Z, Hurvitz S, Tseng LM, Zhang Q, Shen K, Liu D, Feng J, Xu B, Wang X, Lee KS, Ng TY, Ridolfi A, Noel-Baron F, Ringeisen F, et al. Efficacy and safety of everolimus in combination with trastuzumab and paclitaxel in Asian patients with HER2+ advanced breast cancer in BOLERO-1. Breast Cancer Research : Bcr. 19: 47. PMID 28399902 DOI: 10.1186/s13058-017-0839-0  0.398
2017 Sonnenblick A, Agbor-Tarh D, Bradbury I, Di Cosimo S, Azim HA, Fumagalli D, Sarp S, Wolff AC, Andersson M, Kroep J, Cufer T, Simon SD, Salman P, Toi M, Harris L, et al. Impact of Diabetes, Insulin, and Metformin Use on the Outcome of Patients With Human Epidermal Growth Factor Receptor 2-Positive Primary Breast Cancer: Analysis From the ALTTO Phase III Randomized Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016697722. PMID 28375706 DOI: 10.1200/JCO.2016.69.7722  0.304
2016 Uehiro N, Sato F, Pu F, Tanaka S, Kawashima M, Kawaguchi K, Sugimoto M, Saji S, Toi M. Circulating cell-free DNA-based epigenetic assay can detect early breast cancer. Breast Cancer Research : Bcr. 18: 129. PMID 27993161 DOI: 10.1186/s13058-016-0788-z  0.392
2016 Itou J, Tanaka S, Li W, Iida A, Sehara-Fujisawa A, Sato F, Toi M. The Sal-like 4 - integrin α6β1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells. Biochimica Et Biophysica Acta. PMID 27773610 DOI: 10.1016/j.bbamcr.2016.10.012  0.308
2016 Benson JR, Jatoi I, Toi M. Treatment of low-risk ductal carcinoma in situ: is nothing better than something? The Lancet. Oncology. 17: e442-e451. PMID 27733270 DOI: 10.1016/S1470-2045(16)30367-9  0.33
2016 Hirata K, Yoshimura M, Inoue M, Yamauchi C, Ogura M, Toi M, Suzuki E, Takeuchi M, Takada M, Hiraoka M. Regional recurrence in breast cancer patients with one to three positive axillary lymph nodes treated with breast-conserving surgery and whole breast irradiation. Journal of Radiation Research. PMID 27422931 DOI: 10.1093/jrr/rrw071  0.423
2016 André F, Hurvitz S, Fasolo A, Tseng LM, Jerusalem G, Wilks S, O'Regan R, Isaacs C, Toi M, Burris H, He W, Robinson D, Riester M, Taran T, Chen D, et al. Molecular Alterations and Everolimus Efficacy in Human Epidermal Growth Factor Receptor 2-Overexpressing Metastatic Breast Cancers: Combined Exploratory Biomarker Analysis From BOLERO-1 and BOLERO-3. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27091708 DOI: 10.1200/JCO.2015.63.9161  0.432
2016 Shi G, Yoshida Y, Yuki K, Nishimura T, Kawata Y, Kawashima M, Iwaisako K, Yoshikawa K, Kurebayashi J, Toi M, Noda M. Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity. Oncotarget. PMID 27058625 DOI: 10.18632/oncotarget.8620  0.412
2016 Li W, Itou J, Tanaka S, Nishimura T, Sato F, Toi M. A homeobox protein, NKX6.1, up-regulates interleukin-6 expression for cell growth in basal-like breast cancer cells. Experimental Cell Research. PMID 27032575 DOI: 10.1016/j.yexcr.2016.03.023  0.395
2016 Ueno T, Saji S, Sugimoto M, Masuda N, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Imoto S, Sasano H, ... Toi M, et al. Clinical significance of the expression of autophagy-associated marker, beclin 1, in breast cancer patients who received neoadjuvant endocrine therapy. Bmc Cancer. 16: 230. PMID 26984766 DOI: 10.1186/s12885-016-2270-9  0.446
2016 Kawaguchi K, Suzuki E, Yamaguchi A, Yamamoto M, Morita S, Toi M. Altered expression of major immune regulatory molecules in peripheral blood immune cells associated with breast cancer. Breast Cancer (Tokyo, Japan). 24: 111-120. PMID 26942414 DOI: 10.1007/s12282-016-0682-7  0.412
2015 Itou J, Tanaka S, Li W, Matsumoto Y, Sato F, Toi M. Data of a fluorescent imaging-based analysis of anti-cancer drug effects on three-dimensional cultures of breast cancer cells. Data in Brief. 5: 429-33. PMID 26958605 DOI: 10.1016/j.dib.2015.09.037  0.394
2015 Kawaguchi-Sakita N, Kaneshiro-Nakagawa K, Kawashima M, Sugimoto M, Tokiwa M, Suzuki E, Kajihara S, Fujita Y, Iwamoto S, Tanaka K, Toi M. Serum immunoglobulin G Fc region N-glycosylation profiling by matrix-assisted laser desorption/ionization mass spectrometry can distinguish breast cancer patients from cancer-free controls. Biochemical and Biophysical Research Communications. PMID 26740182 DOI: 10.1016/J.Bbrc.2015.12.114  0.321
2015 Fakhrejahani E, Torii M, Kitai T, Kanao S, Asao Y, Hashizume Y, Mikami Y, Yamaga I, Kataoka M, Sugie T, Takada M, Haga H, Togashi K, Shiina T, Toi M. Clinical Report on the First Prototype of a Photoacoustic Tomography System with Dual Illumination for Breast Cancer Imaging. Plos One. 10: e0139113. PMID 26506106 DOI: 10.1371/journal.pone.0139113  0.388
2015 Sato F, Toi M. [Molecular targeted therapy and genomic evolution of breast cancer]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 73: 1364-72. PMID 26281691  0.427
2015 Sugie T, Kinoshita T, Masuda N, Sawada T, Yamauchi A, Kuroi K, Taguchi T, Bando H, Yamashiro H, Lee T, Shinkura N, Kato H, Ikeda T, Yoshimura K, Ueyama H, ... Toi M, et al. Evaluation of the Clinical Utility of the ICG Fluorescence Method Compared with the Radioisotope Method for Sentinel Lymph Node Biopsy in Breast Cancer. Annals of Surgical Oncology. PMID 26275781 DOI: 10.1245/s10434-015-4809-4  0.315
2015 Ueno T, Utsumi J, Toi M, Shimizu K. Characteristic Gene Expression Profiles of Human Fibroblasts and Breast Cancer Cells in a Newly Developed Bilateral Coculture System. Biomed Research International. 2015: 960840. PMID 26171396 DOI: 10.1155/2015/960840  0.43
2015 Hurvitz SA, Andre F, Jiang Z, Shao Z, Mano MS, Neciosup SP, Tseng LM, Zhang Q, Shen K, Liu D, Dreosti LM, Burris HA, Toi M, Buyse ME, Cabaribere D, et al. Combination of everolimus with trastuzumab plus paclitaxel as first-line treatment for patients with HER2-positive advanced breast cancer (BOLERO-1): a phase 3, randomised, double-blind, multicentre trial. The Lancet. Oncology. 16: 816-29. PMID 26092818 DOI: 10.1016/S1470-2045(15)00051-0  0.403
2015 Sato F, Saji S, Toi M. Genomic tumor evolution of breast cancer. Breast Cancer (Tokyo, Japan). PMID 25998191 DOI: 10.1007/s12282-015-0617-8  0.371
2015 Toi M, Winer EP, Benson JR, Inamoto T, Forbes JF, von Minckwitz G, Robertson JF, Grobmyer SR, Jatoi I, Sasano H, Kunkler I, Ho AY, Yamauchi C, Chow LW, Huang CS, et al. Personalization of loco-regional care for primary breast cancer patients (part 2). Future Oncology (London, England). 11: 1301-5. PMID 25952778 DOI: 10.2217/fon.15.66  0.435
2015 Toi M, Winer EP, Benson JR, Inamoto T, Forbes JF, von Minckwitz G, Robertson JF, Grobmyer SR, Jatoi I, Sasano H, Kunkler I, Ho AY, Yamauchi C, Chow LW, Huang CS, et al. Personalization of loco-regional care for primary breast cancer patients (part 1). Future Oncology (London, England). 11: 1297-300. PMID 25952777 DOI: 10.2217/fon.15.65  0.414
2015 Yamshiro H, Iwata H, Masuda N, Yamamoto N, Nishimura R, Ohtani S, Sato N, Takahashi M, Kamio T, Yamazaki K, Saito T, Kato M, Lee T, Ohno S, Kuroi K, ... ... Toi M, et al. Erratum to: Outcomes of trastuzumab therapy in HER2‑positive early breast cancer patients. International Journal of Clinical Oncology. PMID 25772578 DOI: 10.1007/S10147-015-0814-7  0.424
2015 Yamshiro H, Iwata H, Masuda N, Yamamoto N, Nishimura R, Ohtani S, Sato N, Takahashi M, Kamio T, Yamazaki K, Saito T, Kato M, Lee T, Ohno S, Kuroi K, ... ... Toi M, et al. Outcomes of trastuzumab therapy in HER2-positive early breast cancer patients. International Journal of Clinical Oncology. PMID 25666483 DOI: 10.1007/s10147-015-0785-8  0.408
2015 Suzuki E, Kataoka TR, Hirata M, Kawaguchi K, Nishie M, Haga H, Toi M. Trogocytosis-mediated expression of HER2 on immune cells may be associated with a pathological complete response to trastuzumab-based primary systemic therapy in HER2-overexpressing breast cancer patients. Bmc Cancer. 15: 39. PMID 25655677 DOI: 10.1186/s12885-015-1041-3  0.428
2015 Mukai H, Noguchi S, Akiyama F, Inaji H, Iwase H, Horiguchi J, Kurebayashi J, Hirata K, Toi M, Kurosumi M, Kohno N, Nishimura R, Nakamura S, Imoto S, Iwase T, et al. 2013 clinical practice guidelines (The Japanese Breast Cancer Society): history, policy and mission. Breast Cancer (Tokyo, Japan). 22: 1-4. PMID 25056934 DOI: 10.1007/s12282-014-0550-2  0.373
2014 Sumi E, Sugie T, Yoshimura K, Tada H, Ikeda T, Suzuki E, Tanaka Y, Teramukai S, Shimizu A, Toi M, Minato N. Effects of zoledronic acid and the association between its efficacy and γδT cells in postmenopausal women with breast cancer treated with preoperative hormonal therapy: a study protocol. Journal of Translational Medicine. 12: 310. PMID 25421542 DOI: 10.1186/s12967-014-0310-2  0.451
2014 Sugimoto M, Takada M, Toi M. Development of Web tools to predict axillary lymph node metastasis and pathological response to neoadjuvant chemotherapy in breast cancer patients. The International Journal of Biological Markers. 29: e372-9. PMID 25096734 DOI: 10.5301/jbm.5000103  0.336
2014 André F, O'Regan R, Ozguroglu M, Toi M, Xu B, Jerusalem G, Masuda N, Wilks S, Arena F, Isaacs C, Yap YS, Papai Z, Lang I, Armstrong A, Lerzo G, et al. Everolimus for women with trastuzumab-resistant, HER2-positive, advanced breast cancer (BOLERO-3): a randomised, double-blind, placebo-controlled phase 3 trial. The Lancet. Oncology. 15: 580-91. PMID 24742739 DOI: 10.1016/S1470-2045(14)70138-X  0.305
2014 Kuroi K, Toi M, Ohno S, Nakamura S, Iwata H, Masuda N, Sato N, Tsuda H, Kurosumi M, Akiyama F. Comparison of different definitions of pathologic complete response in operable breast cancer: a pooled analysis of three prospective neoadjuvant studies of JBCRG. Breast Cancer (Tokyo, Japan). PMID 24574277 DOI: 10.1007/s12282-014-0524-4  0.435
2014 Fakhrejahani E, Toi M. Antiangiogenesis therapy for breast cancer: an update and perspectives from clinical trials. Japanese Journal of Clinical Oncology. 44: 197-207. PMID 24474817 DOI: 10.1093/jjco/hyt201  0.421
2014 Yamashiro H, Takada M, Nakatani E, Imai S, Yamauchi A, Tsuyuki S, Matsutani Y, Sakata S, Wada Y, Okamura R, Harada T, Tanaka F, Moriguchi Y, Kato H, Higashide S, ... ... Toi M, et al. Prevalence and risk factors of bone metastasis and skeletal related events in patients with primary breast cancer in Japan. International Journal of Clinical Oncology. 19: 852-62. PMID 24292334 DOI: 10.1007/s10147-013-0643-5  0.379
2014 Ueno T, Masuda N, Yamanaka T, Saji S, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Sasano H, Toi M. Evaluating the 21-gene assay Recurrence Score® as a predictor of clinical response to 24 weeks of neoadjuvant exemestane in estrogen receptor-positive breast cancer. International Journal of Clinical Oncology. 19: 607-13. PMID 24101215 DOI: 10.1007/s10147-013-0614-x  0.396
2014 Toi M, Saeki T, Iwata H, Inoue K, Tokuda Y, Sato Y, Ito Y, Aogi K, Takatsuka Y, Arioka H. A multicenter phase II study of TSU-68, an oral multiple tyrosine kinase inhibitor, in combination with docetaxel in metastatic breast cancer patients with anthracycline resistance. Breast Cancer (Tokyo, Japan). 21: 20-7. PMID 22382811 DOI: 10.1007/s12282-012-0344-3  0.311
2014 Takuwa H, Ueno T, Ishiguro H, Mikami Y, Kanao S, Takada M, Sugie T, Toi M. A case of metaplastic breast cancer that showed a good response to platinum-based preoperative chemotherapy Breast Cancer. 21: 504-507. PMID 21526425 DOI: 10.1007/s12282-011-0269-2  0.455
2013 Kuroi K, Toi M, Ohno S, Nakamura S, Iwata H, Masuda N, Sato N, Tsuda H, Kurosumi M, Akiyama F. Prognostic significance of subtype and pathologic response in operable breast cancer; a pooled analysis of prospective neoadjuvant studies of JBCRG. Breast Cancer (Tokyo, Japan). PMID 24338638 DOI: 10.1007/s12282-013-0511-1  0.437
2013 Sugimoto M, Takada M, Toi M. Comparison of robustness against missing values of alternative decision tree and multiple logistic regression for predicting clinical data in primary breast cancer. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2013: 3054-7. PMID 24110372 DOI: 10.1109/EMBC.2013.6610185  0.35
2013 Kaga C, Takagi A, Kano M, Kado S, Kato I, Sakai M, Miyazaki K, Nanno M, Ishikawa F, Ohashi Y, Toi M. Lactobacillus casei Shirota enhances the preventive efficacy of soymilk in chemically induced breast cancer. Cancer Science. 104: 1508-14. PMID 23992486 DOI: 10.1111/cas.12268  0.37
2013 Toi M, Hirota S, Tomotaki A, Sato N, Hozumi Y, Anan K, Nagashima T, Tokuda Y, Masuda N, Ohsumi S, Ohno S, Takahashi M, Hayashi H, Yamamoto S, Ohashi Y. Probiotic Beverage with Soy Isoflavone Consumption for Breast Cancer Prevention: A Case-control Study. Current Nutrition and Food Science. 9: 194-200. PMID 23966890 DOI: 10.2174/15734013113099990001  0.479
2013 Itou J, Matsumoto Y, Yoshikawa K, Toi M. Sal-like 4 (SALL4) suppresses CDH1 expression and maintains cell dispersion in basal-like breast cancer. Febs Letters. 587: 3115-21. PMID 23954296 DOI: 10.1016/j.febslet.2013.07.049  0.439
2013 Cameron D, Brown J, Dent R, Jackisch C, Mackey J, Pivot X, Steger GG, Suter TM, Toi M, Parmar M, Laeufle R, Im YH, Romieu G, Harvey V, Lipatov O, et al. Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): primary results of a randomised, phase 3 trial. The Lancet. Oncology. 14: 933-42. PMID 23932548 DOI: 10.1016/S1470-2045(13)70335-8  0.458
2013 Mikami Y, Ueno T, Yoshimura K, Tsuda H, Kurosumi M, Masuda S, Horii R, Toi M, Sasano H. Interobserver concordance of Ki67 labeling index in breast cancer: Japan Breast Cancer Research Group Ki67 ring study. Cancer Science. 104: 1539-43. PMID 23905924 DOI: 10.1111/cas.12245  0.476
2013 Horvath A, Pakala SB, Mudvari P, Reddy SD, Ohshiro K, Casimiro S, Pires R, Fuqua SA, Toi M, Costa L, Nair SS, Sukumar S, Kumar R. Novel insights into breast cancer genetic variance through RNA sequencing. Scientific Reports. 3: 2256. PMID 23884293 DOI: 10.1038/Srep02256  0.432
2013 Kawashima M, Iwamoto N, Kawaguchi-Sakita N, Sugimoto M, Ueno T, Mikami Y, Terasawa K, Sato TA, Tanaka K, Shimizu K, Toi M. High-resolution imaging mass spectrometry reveals detailed spatial distribution of phosphatidylinositols in human breast cancer. Cancer Science. 104: 1372-9. PMID 23837649 DOI: 10.1111/cas.12229  0.444
2013 Tsuji W, Ishiguro H, Tanaka S, Takeuchi M, Ueno T, Toi M. Orally administered S-1 suppresses circulating endothelial cell counts in metastatic breast cancer patients. International Journal of Clinical Oncology. 19: 452-9. PMID 23739924 DOI: 10.1007/s10147-013-0570-5  0.364
2013 Komuro M, Suzuki K, Kanebako M, Kawahara T, Otoi T, Kitazato K, Inagi T, Makino K, Toi M, Terada H. Novel iontophoretic administration method for local therapy of breast cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. 168: 298-306. PMID 23562634 DOI: 10.1016/j.jconrel.2013.03.021  0.327
2013 Ishiguro H, Saji S, Toi M. [Clinical pharmacology of targeted drug for breast cancer]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 443-6. PMID 23513881  0.393
2013 Ohno S, Kuroi K, Toi M. An overview of the Japan Breast Cancer Research Group (JBCRG) activities. Breast Cancer (Tokyo, Japan). 20: 291-5. PMID 23494592 DOI: 10.1007/s12282-012-0420-8  0.451
2013 Chow LW, Tung SY, Ng TY, Im SA, Lee MH, Yip AY, Toi M, Glück S. Concurrent celecoxib with 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel for stages II - III invasive breast cancer: the OOTR-N001 study. Expert Opinion On Investigational Drugs. 22: 299-307. PMID 23394482 DOI: 10.1517/13543784.2013.766715  0.319
2013 Masuda N, Toi M, Kuroi K. [Current activities and perspective of JBCRG (Japan Breast Cancer Research Group)]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 763-72. PMID 23350501  0.407
2013 Kitai T, Toi M. [Photoacoustic mammography for the diagnosis of breast cancer]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 326-30. PMID 23350415  0.492
2013 Sugie T, Murata-Hirai K, Iwasaki M, Morita CT, Li W, Okamura H, Minato N, Toi M, Tanaka Y. Zoledronic acid-induced expansion of γδ T cells from early-stage breast cancer patients: effect of IL-18 on helper NK cells. Cancer Immunology, Immunotherapy : Cii. 62: 677-87. PMID 23151944 DOI: 10.1007/S00262-012-1368-4  0.374
2013 Suzuki Y, Saeki T, Aogi K, Toi M, Fujii H, Inoue K, Watanabe T, Fujiwara Y, Ito Y, Takatsuka Y, Iwata H, Arioka H, Tokuda Y. A multicenter phase II study of TSU-68, a novel oral multiple tyrosine kinase inhibitor, in patients with metastatic breast cancer progressing despite prior treatment with an anthracycline-containing regimen and taxane. International Journal of Clinical Oncology. 18: 590-7. PMID 22585426 DOI: 10.1007/s10147-012-0421-9  0.38
2012 Chan MS, Wang L, Felizola SJ, Ueno T, Toi M, Loo W, Chow LW, Suzuki T, Sasano H. Changes of tumor infiltrating lymphocyte subtypes before and after neoadjuvant endocrine therapy in estrogen receptor-positive breast cancer patients--an immunohistochemical study of Cd8+ and Foxp3+ using double immunostaining with correlation to the pathobiological response of the patients. The International Journal of Biological Markers. 27: e295-304. PMID 23280127 DOI: 10.5301/JBM.2012.10439  0.315
2012 Toi M, Benson JR, Winer EP, Forbes JF, von Minckwitz G, Golshan M, Robertson JF, Sasano H, Cole BF, Chow LW, Pegram MD, Han W, Huang CS, Ikeda T, Kanao S, et al. Preoperative systemic therapy in locoregional management of early breast cancer: highlights from the Kyoto Breast Cancer Consensus Conference. Breast Cancer Research and Treatment. 136: 919-26. PMID 23143284 DOI: 10.1007/s10549-012-2333-9  0.363
2012 Suzuki R, Saji S, Toi M. Impact of body mass index on breast cancer in accordance with the life-stage of women. Frontiers in Oncology. 2: 123. PMID 23061041 DOI: 10.3389/fonc.2012.00123  0.428
2012 Takeuchi M, Sugie T, Abdelazeem K, Kato H, Shinkura N, Takada M, Yamashiro H, Ueno T, Toi M. Lymphatic mapping with fluorescence navigation using indocyanine green and axillary surgery in patients with primary breast cancer. The Breast Journal. 18: 535-41. PMID 23009222 DOI: 10.1111/tbj.12004  0.364
2012 Iima M, Nakamoto Y, Kanao S, Sugie T, Ueno T, Kawada M, Mikami Y, Toi M, Togashi K. Clinical performance of 2 dedicated PET scanners for breast imaging: initial evaluation. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1534-42. PMID 22933819 DOI: 10.2967/jnumed.111.100958  0.423
2012 Kitai T, Torii M, Sugie T, Kanao S, Mikami Y, Shiina T, Toi M. Photoacoustic mammography: initial clinical results. Breast Cancer (Tokyo, Japan). 21: 146-53. PMID 22484692 DOI: 10.1007/s12282-012-0363-0  0.318
2012 Tsuji W, Teramukai S, Ueno M, Toi M, Inamoto T. Prognostic factors for survival after first recurrence in breast cancer: a retrospective analysis of 252 recurrent cases at a single institution. Breast Cancer (Tokyo, Japan). 21: 86-95. PMID 22477265 DOI: 10.1007/s12282-012-0358-x  0.409
2012 Ichikawa T, Sato F, Terasawa K, Tsuchiya S, Toi M, Tsujimoto G, Shimizu K. Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells. Plos One. 7: e31422. PMID 22384020 DOI: 10.1371/journal.pone.0031422  0.357
2012 Toi M. [Breast and endocrine tumor-recent progress and future view for treatment of breast cancer-]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 38: 2558. PMID 22315737  0.474
2012 Ueno T, Emi M, Sato H, Ito N, Muta M, Kuroi K, Toi M. Genome-wide copy number analysis in primary breast cancer. Expert Opinion On Therapeutic Targets. 16: S31-5. PMID 22313367 DOI: 10.1517/14728222.2011.636739  0.405
2012 Chan MS, Wang L, Chanplakorn N, Tamaki K, Ueno T, Toi M, Loo WT, Chow LW, Suzuki T, Sasano H. Effects of estrogen depletion on angiogenesis in estrogen-receptor-positive breast carcinoma--an immunohistochemical study of vasohibin-1 and CD31 with correlation to pathobiological response of the patients in neoadjuvant aromatase inhibitor therapy. Expert Opinion On Therapeutic Targets. 16: S69-78. PMID 22309693 DOI: 10.1517/14728222.2011.628938  0.441
2012 Takeda K, Kanao S, Okada T, Kataoka M, Ueno T, Toi M, Ishiguro H, Mikami Y, Togashi K. Assessment of CAD-generated tumor volumes measured using MRI in breast cancers before and after neoadjuvant chemotherapy. European Journal of Radiology. 81: 2627-31. PMID 22221829 DOI: 10.1016/j.ejrad.2011.12.013  0.4
2012 Takada M, Saji S, Masuda N, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Ueno T, Sasano H, Toi M. Relationship between body mass index and preoperative treatment response to aromatase inhibitor exemestane in postmenopausal patients with primary breast cancer. Breast (Edinburgh, Scotland). 21: 40-5. PMID 21855342 DOI: 10.1016/j.breast.2011.07.015  0.39
2011 Han HS, Reis IM, Zhao W, Kuroi K, Toi M, Suzuki E, Syme R, Chow L, Yip AY, Glück S. Racial differences in acute toxicities of neoadjuvant or adjuvant chemotherapy in patients with early-stage breast cancer. European Journal of Cancer (Oxford, England : 1990). 47: 2537-45. PMID 21741825 DOI: 10.1016/j.ejca.2011.06.027  0.427
2011 Ali AM, Ueno T, Tanaka S, Takada M, Ishiguro H, Abdellah AZ, Toi M. Determining circulating endothelial cells using CellSearch system during preoperative systemic chemotherapy in breast cancer patients. European Journal of Cancer (Oxford, England : 1990). 47: 2265-72. PMID 21737256 DOI: 10.1016/j.ejca.2011.06.015  0.469
2011 Iwata H, Sato N, Masuda N, Nakamura S, Yamamoto N, Kuroi K, Kurosumi M, Tsuda H, Akiyama F, Ohashi Y, Toi M. Docetaxel followed by fluorouracil/epirubicin/cyclophosphamide as neoadjuvant chemotherapy for patients with primary breast cancer. Japanese Journal of Clinical Oncology. 41: 867-75. PMID 21719750 DOI: 10.1093/jjco/hyr081  0.315
2011 Qian N, Ueno T, Kawaguchi-Sakita N, Kawashima M, Yoshida N, Mikami Y, Wakasa T, Shintaku M, Tsuyuki S, Inamoto T, Toi M. Prognostic significance of tumor/stromal caveolin-1 expression in breast cancer patients. Cancer Science. 102: 1590-6. PMID 21585620 DOI: 10.1111/j.1349-7006.2011.01985.x  0.402
2011 Toi M, Yasui W, Ito H, Tahara E. Recent progress in carcinogenesis, progression and therapy of breast cancer: the 20th Hiroshima Cancer Seminar--the 4th Three Universities' Consortium International Symposium, October 2010: 31 October 2010, International Conference Center Hiroshima. Japanese Journal of Clinical Oncology. 41: 924-30. PMID 21565925 DOI: 10.1093/jjco/hyr054  0.449
2011 Toi M, Winer EP, Inamoto T, Benson JR, Forbes JF, Mitsumori M, Robertson JF, Sasano H, von Minckwitz G, Yamauchi A, Klimberg VS. Identifying gaps in the locoregional management of early breast cancer: highlights from the Kyoto Consensus Conference. Annals of Surgical Oncology. 18: 2885-92. PMID 21431404 DOI: 10.1245/s10434-011-1666-7  0.318
2011 Takada M, Toi M. [Surgery for breast cancer -- from radical mastectomy to breast-conserving surgery]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 38: 173-8. PMID 21368479  0.444
2011 Honda M, Saji S, Horiguchi S, Suzuki E, Aruga T, Horiguchi K, Kitagawa D, Sekine S, Funata N, Toi M, Kuroi K. Clinicopathological analysis of ten patients with metaplastic squamous cell carcinoma of the breast. Surgery Today. 41: 328-32. PMID 21365411 DOI: 10.1007/s00595-009-4276-2  0.377
2011 Toi M. [Current organ topics: chemotherapy of breast cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 37: 2844. PMID 21235089  0.453
2011 Toi M, Saji S, Masuda N, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Takada M, Ueno T, Saji S, et al. Ki67 index changes, pathological response and clinical benefits in primary breast cancer patients treated with 24 weeks of aromatase inhibition. Cancer Science. 102: 858-65. PMID 21231986 DOI: 10.1111/j.1349-7006.2011.01867.x  0.44
2011 Kondo M, Hoshi SL, Yamanaka T, Ishiguro H, Toi M. Economic evaluation of the 21-gene signature (Oncotype DX) in lymph node-negative/positive, hormone receptor-positive early-stage breast cancer based on Japanese validation study (JBCRG-TR03). Breast Cancer Research and Treatment. 127: 739-49. PMID 21082239 DOI: 10.1007/s10549-010-1243-y  0.308
2010 Horiguchi S, Hishima T, Hayashi Y, Shiozawa Y, Horiguchi K, Kuroi K, Toi M, Funata N, Eishi Y. HER-2/neu cytoplasmic staining is correlated with neuroendocrine differentiation in breast carcinoma. Journal of Medical and Dental Sciences. 57: 155-63. PMID 21073134  0.455
2010 Yamashiro H, Toi M. [Molecular targeted therapy for breast cancer treatment, challenge to cure]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 68: 1854-8. PMID 20954329  0.411
2010 Yiu CC, Chanplakorn N, Chan MS, Loo WT, Chow LW, Toi M, Sasano H. Down-regulation of heat-shock protein 70 (HSP-70) correlated with responsiveness to neoadjuvant aromatase inhibitor therapy in breast cancer patients. Anticancer Research. 30: 3465-72. PMID 20944124  0.378
2010 Toi M, Ohashi Y, Seow A, Moriya T, Tse G, Sasano H, Park BW, Chow LW, Laudico AV, Yip CH, Ueno E, Ishiguro H, Bando H. The Breast Cancer Working Group presentation was divided into three sections: the epidemiology, pathology and treatment of breast cancer. Japanese Journal of Clinical Oncology. 40: i13-18. PMID 20870914 DOI: 10.1093/jjco/hyq122  0.508
2010 Aogi K, Yoshida M, Sagara Y, Kamigaki S, Okazaki M, Funai J, Fujimoto T, Toi M, Saeki T, Takashima S. The efficacy and safety of gemcitabine plus paclitaxel combination first-line therapy for Japanese patients with metastatic breast cancer including triple-negative phenotype. Cancer Chemotherapy and Pharmacology. 67: 1007-15. PMID 20628744 DOI: 10.1007/s00280-010-1390-1  0.348
2010 Toi M, Iwata H, Yamanaka T, Masuda N, Ohno S, Nakamura S, Nakayama T, Kashiwaba M, Kamigaki S, Kuroi K. Clinical significance of the 21-gene signature (Oncotype DX) in hormone receptor-positive early stage primary breast cancer in the Japanese population. Cancer. 116: 3112-8. PMID 20564629 DOI: 10.1002/cncr.25206  0.369
2010 Kitagawa D, Saji S, Horiguchi S, Satoh Y, Horiguchi K, Toi M, Funata N, Kuroi K. Alternation of estrogen receptor and progesterone receptor expression in primary breast cancer patients treated with neoadjuvant chemotherapy. The Breast Journal. 16: 435-6. PMID 20545937 DOI: 10.1111/j.1524-4741.2010.00943.x  0.376
2010 Takada M, Terunuma H, Deng X, Dewan MZ, Saji S, Kuroi K, Yamamoto N, Toi M. Refractory lung metastasis from breast cancer treated with multidisciplinary therapy including an immunological approach. Breast Cancer (Tokyo, Japan). 18: 64-7. PMID 20354831 DOI: 10.1007/s12282-010-0198-5  0.348
2010 Ishiguro H, Kondo M, Hoshi SL, Takada M, Nakamura S, Teramukai S, Yanagihara K, Toi M. Economic evaluation of intensive chemotherapy with prophylactic granulocyte colony-stimulating factor for patients with high-risk early breast cancer in Japan. Clinical Therapeutics. 32: 311-26. PMID 20206789 DOI: 10.1016/j.clinthera.2010.01.029  0.37
2010 Toi M, Sperinde J, Huang W, Saji S, Winslow J, Jin X, Tan Y, Ohno S, Nakamura S, Iwata H, Masuda N, Aogi K, Morita S, Petropoulos C, Bates M. Differential survival following trastuzumab treatment based on quantitative HER2 expression and HER2 homodimers in a clinic-based cohort of patients with metastatic breast cancer. Bmc Cancer. 10: 56. PMID 20178580 DOI: 10.1186/1471-2407-10-56  0.373
2010 Sugie T, Tanaka Y, Toi M. [New development in breast cancer therapy. III. Zoledronic acid and anti-tumor immunity in breast cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 36: 2555-9. PMID 20104681  0.498
2010 Kimura M, Tominaga T, Takatsuka Y, Toi M, Abe R, Koyama H, Takashima S, Nomura Y, Miura S, Kimijima I, Tashiro H, Ohashi Y. Randomized trial of cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil with node-positive breast cancer in Japan. Breast Cancer (Tokyo, Japan). 17: 190-8. PMID 19575284 DOI: 10.1007/s12282-009-0132-x  0.33
2009 Kondo M, Hoshi SL, Toi M. Budget impact analysis of chemoprevention of breast cancer with tamoxifen and raloxifene among high-risk women in Japan. Japanese Journal of Clinical Oncology. 39: 767-70. PMID 19656807 DOI: 10.1093/jjco/hyp081  0.364
2009 Aruga T, Suzuki E, Saji S, Horiguchi S, Horiguchi K, Sekine S, Kitagawa D, Funata N, Toi M, Sugihara K, Kuroi K. A low number of tumor-infiltrating FOXP3-positive cells during primary systemic chemotherapy correlates with favorable anti-tumor response in patients with breast cancer. Oncology Reports. 22: 273-8. PMID 19578766  0.38
2009 Toi M, Sasano H, Ellis MJ. [Future prospects of neoadjuvant endocrine therapy in postmenopausal breast cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 36: 1035-42. PMID 19542732  0.435
2009 Noguchi S, Toi M. From standardization to personalization in breast cancer treatment. Breast Cancer (Tokyo, Japan). 16: 241-2. PMID 19350355 DOI: 10.1007/s12282-009-0106-z  0.459
2009 Dewan MZ, Takada M, Terunuma H, Deng X, Ahmed S, Yamamoto N, Toi M. Natural killer activity of peripheral-blood mononuclear cells in breast cancer patients. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 63: 703-6. PMID 19269774 DOI: 10.1016/j.biopha.2009.02.003  0.422
2009 Toi M, Yamashiro H, Tsuji W. Risk reduction of distant metastasis in hormone-sensitive postmenopausal breast cancer. Breast Cancer (Tokyo, Japan). 16: 207-18. PMID 19259765 DOI: 10.1007/s12282-009-0096-x  0.431
2009 Takada M, Ishiguro H, Toi M. [Treatment for breast cancer and endocrine neoplasm]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 35: 2344-50. PMID 19117102  0.488
2009 Toi M. [Breast and endocrine tumor]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 35: 2338. PMID 19117100  0.361
2008 Kiba T, Inamoto T, Nishimura T, Ueno M, Yanagihara K, Teramukai S, Kato H, Toi M, Fukushima M. The reversal of recurrence hazard rate between ER positive and negative breast cancer patients with axillary lymph node dissection (pathological stage I-III) 3 years after surgery. Bmc Cancer. 8: 323. PMID 18990247 DOI: 10.1186/1471-2407-8-323  0.343
2008 Toi M. Novel targeting therapy concept for breast cancer treatment. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 132: 177-9. PMID 18787301 DOI: 10.1254/fpj.132.177  0.421
2008 Yoshibayashi H, Ishiguro H, Takada M, Takeuchi M, Yamashiro H, Ueno T, Kato H, Yoshikawa K, Kanao S, Yamauchi C, Mikami Y, Toi M. [A case of primary breast cancer who responded remarkably to the neoadjuvant chemotherapy with the combination of docetaxel and cyclophosphamide]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 35: 987-90. PMID 18633230  0.462
2008 Tokudome N, Ito Y, Hatake K, Toi M, Sano M, Iwata H, Sato Y, Saeki T, Aogi K, Takashima S. Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II and pharmacokinetic study in Japan. Anti-Cancer Drugs. 19: 753-9. PMID 18594220 DOI: 10.1097/CAD.0b013e328302eb15  0.349
2008 Yagata H, Nakamura S, Toi M, Bando H, Ohno S, Kataoka A. Evaluation of circulating tumor cells in patients with breast cancer: multi-institutional clinical trial in Japan. International Journal of Clinical Oncology. 13: 252-6. PMID 18553236 DOI: 10.1007/s10147-007-0748-9  0.398
2008 Chow LW, Yip AY, Loo WT, Lam CK, Toi M. Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer. The Journal of Steroid Biochemistry and Molecular Biology. 111: 13-7. PMID 18514508 DOI: 10.1016/j.jsbmb.2008.04.004  0.442
2008 Yamashiro H, Toi M. Update of evidence in chemotherapy for breast cancer. International Journal of Clinical Oncology. 13: 3-7. PMID 18307012 DOI: 10.1007/s10147-007-0719-1  0.502
2008 Chow LW, Yip AY, Loo WT, Toi M. Evaluation of neoadjuvant inhibition of aromatase activity and signal transduction in breast cancer. Cancer Letters. 262: 232-8. PMID 18248884 DOI: 10.1016/j.canlet.2007.12.003  0.409
2008 Saji S, Toi M, Morita S, Iwata H, Ito Y, Ohno S, Kobayashi T, Hozumi Y, Sakamoto J. Dose-finding phase I and pharmacokinetic study of capecitabine (Xeloda) in combination with epirubicin and cyclophosphamide (CEX) in patients with inoperable or metastatic breast cancer. Oncology. 72: 330-7. PMID 18187954 DOI: 10.1159/000113062  0.424
2008 Toi M. Long-term outcomes of aromatase inhibition for breast cancer. The Lancet. Oncology. 9: 8-10. PMID 18177815 DOI: 10.1016/S1470-2045(07)70392-3  0.39
2008 Toi M, Nakamura S, Kuroi K, Iwata H, Ohno S, Masuda N, Kusama M, Yamazaki K, Hisamatsu K, Sato Y, Kashiwaba M, Kaise H, Kurosumi M, Tsuda H, Akiyama F, et al. Phase II study of preoperative sequential FEC and docetaxel predicts of pathological response and disease free survival. Breast Cancer Research and Treatment. 110: 531-9. PMID 17879158 DOI: 10.1007/s10549-007-9744-z  0.32
2007 Takada M, Toi M. [Primary systemic chemotherapy for breast cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 34: 1730-4. PMID 18030005  0.417
2007 Toi M, Ikeda T, Akiyama F, Kurosumi M, Tsuda H, Sakamoto G, Abe O. Predictive implications of nucleoside metabolizing enzymes in premenopausal women with node-positive primary breast cancer who were randomly assigned to receive tamoxifen alone or tamoxifen plus tegafur-uracil as adjuvant therapy. International Journal of Oncology. 31: 899-906. PMID 17786323  0.4
2007 Kitagawa D, Toi M. [Current status and the perspective of treatment strategy for the patients with advanced or recurrent breast cancer]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 396-401. PMID 17682183  0.428
2007 Olofsson MH, Ueno T, Pan Y, Xu R, Cai F, van der Kuip H, Muerdter TE, Sonnenberg M, Aulitzky WE, Schwarz S, Andersson E, Shoshan MC, Havelka AM, Toi M, Linder S. Cytokeratin-18 is a useful serum biomarker for early determination of response of breast carcinomas to chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3198-206. PMID 17545523 DOI: 10.1158/1078-0432.CCR-07-0009  0.426
2007 Suzuki E, Toi M. Improving the efficacy of trastuzumab in breast cancer. Cancer Science. 98: 767-71. PMID 17428260 DOI: 10.1111/j.1349-7006.2007.00455.x  0.462
2006 Saeki T, Nomizu T, Toi M, Ito Y, Noguchi S, Kobayashi T, Asaga T, Minami H, Yamamoto N, Aogi K, Ikeda T, Ohashi Y, Sato W, Tsuruo T. Dofequidar fumarate (MS-209) in combination with cyclophosphamide, doxorubicin, and fluorouracil for patients with advanced or recurrent breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 411-7. PMID 17179098 DOI: 10.1200/JCO.2006.08.1646  0.431
2006 Dewan MZ, Terunuma H, Takada M, Tanaka Y, Abe H, Sata T, Toi M, Yamamoto N. Role of natural killer cells in hormone-independent rapid tumor formation and spontaneous metastasis of breast cancer cells in vivo. Breast Cancer Research and Treatment. 104: 267-75. PMID 17066321 DOI: 10.1007/s10549-006-9416-4  0.345
2006 Suzuki T, Toi M, Saji S, Horiguchi K, Aruga T, Suzuki E, Horiguchi S, Funata N, Karasawa K, Kamata N. Early breast cancer. International Journal of Clinical Oncology. 11: 108-19. PMID 16622745 DOI: 10.1007/s10147-006-0564-7  0.469
2006 Suzuki E, Toi M. [Neoadjuvant Chemotherapy in breast cancer]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 64: 536-9. PMID 16529046  0.443
2006 Saeki T, Kimura T, Toi M, Taguchi T. A pilot phase II study of capecitabine in advanced or recurrent breast cancer. Breast Cancer (Tokyo, Japan). 13: 49-57. PMID 16518062 DOI: 10.2325/jbcs.13.49  0.401
2006 Kondo M, Toi M. Cost-effective treatment options in first-line therapy for advanced breast cancer in Japan. Expert Review of Anticancer Therapy. 6: 197-204. PMID 16445372 DOI: 10.1586/14737140.6.2.197  0.409
2006 Saji S, Hirose M, Toi M. Clinical significance of estrogen receptor beta in breast cancer. Cancer Chemotherapy and Pharmacology. 21-6. PMID 16273360 DOI: 10.1007/s00280-005-0107-3  0.449
2005 Albain KS, de la Garza Salazar J, Pienkowski T, Aapro M, Bergh J, Caleffi M, Coleman R, Eiermann W, Icli F, Pegram M, Piccart M, Snyder R, Toi M, Hortobagyi GN. Reducing the global breast cancer burden: the importance of patterns of care research. Clinical Breast Cancer. 6: 412-20. PMID 16381624 DOI: 10.3816/CBC.2005.n.045  0.33
2005 Saji S, Toi M. Aromatase inhibitors and other novel agents in breast cancer treatment. Expert Opinion On Emerging Drugs. 7: 303-19. PMID 15989553 DOI: 10.1517/14728214.7.2.303  0.435
2005 Toi M, Saeki T, Aogi K, Sano M, Hatake K, Asaga T, Tokuda Y, Mitsuyama S, Kimura M, Kobayashi T, Tamura M, Tabei T, Shin E, Nishimura R, Ohno S, et al. Late phase II clinical study of vinorelbine monotherapy in advanced or recurrent breast cancer previously treated with anthracyclines and taxanes. Japanese Journal of Clinical Oncology. 35: 310-5. PMID 15930037 DOI: 10.1093/jjco/hyi090  0.451
2005 Iwata H, Nakamura S, Toi M, Shin E, Masuda N, Ohno S, Takatsuka Y, Hisamatsu K, Yamazaki K, Kusama M, Kaise H, Sato Y, Kuroi K, Akiyama F, Tsuda H, et al. Interim analysis of a phase II trial of cyclophosphamide, epirubicin and 5-fluorouracil (CEF) followed by docetaxel as preoperative chemotherapy for early stage Breast carcinoma Breast Cancer. 12: 99-103. PMID 15858439 DOI: 10.2325/jbcs.12.99  0.317
2005 Toi M, Takebayashi Y, Chow LW. Translational research in breast cancer Breast Cancer. 12: 86-90. PMID 15858437 DOI: 10.2325/jbcs.12.86  0.357
2005 Hiramatsu K, Takahashi K, Yamaguchi T, Matsumoto H, Miyamoto H, Tanaka S, Tanaka C, Tamamori Y, Imajo M, Kawaguchi M, Toi M, Mori T, Kawakita M. N(1),N(12)-Diacetylspermine as a sensitive and specific novel marker for early- and late-stage colorectal and breast cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2986-90. PMID 15837752 DOI: 10.1158/1078-0432.CCR-04-2275  0.37
2005 Saji S, Kawakami M, Hayashi S, Yoshida N, Hirose M, Horiguchi S, Itoh A, Funata N, Schreiber SL, Yoshida M, Toi M. Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer. Oncogene. 24: 4531-9. PMID 15806142 DOI: 10.1038/Sj.Onc.1208646  0.347
2005 Toi M, Bando H, Chow LW. Novel insights in clinical trials with preoperative systemic therapy for primary breast cancer. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 58: 531-5. PMID 15599986 DOI: 10.1016/j.biopha.2003.12.016  0.397
2004 Nakanishi C, Yamaguchi T, Iijima T, Saji S, Toi M, Mori T, Miyaki M. Germline mutation of the LKB1/STK11 gene with loss of the normal allele in an aggressive breast cancer of Peutz-Jeghers syndrome. Oncology. 67: 476-9. PMID 15714005 DOI: 10.1159/000082933  0.347
2004 Saji S, Hirose M, Toi M. Novel sensitizing agents: potential contribution of COX-2 inhibitor for endocrine therapy of breast cancer. Breast Cancer (Tokyo, Japan). 11: 129-33. PMID 15550858 DOI: 10.1007/BF02968291  0.392
2004 Yamashiro H, Toyama K, Bando H, Saji S, Toi M. [Trastuzumab treatment for breast cancer]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 62: 1305-11. PMID 15283148  0.486
2004 Takada M, Kataoka A, Toi M, Bando H, Toyama K, Horiguchi S, Ueno T, Linder S, Saji S, Hayashi Y, Funata N, Kinoshita J, Murakami S, Ohono S. A close association between alteration in growth kinetics by neoadjuvant chemotherapy and survival outcome in primary breast cancer. International Journal of Oncology. 25: 397-405. PMID 15254737  0.4
2004 Kawakita M, Hiramatsu K, Sugimoto M, Takahashi K, Toi M. [Clinical usefulness of urinary diacetylpolyamines as novel tumor markers]. Rinsho Byori. the Japanese Journal of Clinical Pathology. 52: 321-7. PMID 15164599  0.305
2004 Kawakami M, Saji S, Toi M. [Controversies in endocrine therapy for breast cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 31: 181-7. PMID 14997748  0.357
2004 Toi M, Bando H, Ramachandran C, Melnick SJ, Imai A, Fife RS, Carr RE, Oikawa T, Lansky EP. Preliminary studies on the anti-angiogenic potential of pomegranate fractions in vitro and in vivo. Angiogenesis. 6: 121-8. PMID 14739618 DOI: 10.1023/B:AGEN.0000011802.81320.e4  0.38
2004 Toi M, Takada M, Bando H, Toyama K, Yamashiro H, Horiguchi S, Saji S. Current status of antibody therapy for breast cancer. Breast Cancer (Tokyo, Japan). 11: 10-4. PMID 14718785 DOI: 10.1007/BF02967994  0.407
2004 Bando H, Toi M, Kitada K, Koike M. Genes commonly upregulated by hypoxia in human breast cancer cells MCF-7 and MDA-MB-231. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 57: 333-40. PMID 14568227 DOI: 10.1016/s0753-3322(03)00098-2  0.405
2004 Yamamoto Y, Yamashita J, Toi M, Muta M, Nagai S, Hanai N, Furuya A, Osawa Y, Saji S, Ogawa M. Immunohistochemical analysis of estrone sulfatase and aromatase in human breast cancer tissues. Oncology Reports. 10: 791-6. PMID 12792725  0.344
2004 Toi M, Bando H, Saji S. Decision tree and paradigms of primary breast cancer: changes elicited by preoperative therapy. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 9: RA90-5. PMID 12761467  0.334
2003 Atiqur Rahman M, Toi M. Anti-angiogenic therapy in breast cancer. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 57: 463-70. PMID 14637390  0.412
2003 Chow LW, Wong JL, Toi M. Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer: preliminary report. The Journal of Steroid Biochemistry and Molecular Biology. 86: 443-7. PMID 14623542  0.436
2003 Kuroi K, Toi M. [Male breast cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 30: 599-605. PMID 12795089  0.461
2003 Tominaga T, Koyama H, Toge T, Miura S, Sugimachi K, Yamaguchi S, Hirata K, Monden Y, Nomura Y, Toi M, Kimijima I, Noguchi S, Sonoo H, Asaishi K, Ikeda T, et al. Randomized controlled trial comparing oral doxifluridine plus oral cyclophosphamide with doxifluridine alone in women with node-positive breast cancer after primary surgery. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 991-8. PMID 12637462 DOI: 10.1200/JCO.2003.06.014  0.418
2003 Saji H, Toi M, Saji S, Koike M, Kohno K, Kuwano M. Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human breast carcinoma. Cancer Letters. 190: 191-7. PMID 12565174 DOI: 10.1016/s0304-3835(02)00590-6  0.35
2003 Kuroi K, Bando H, Saji S, Toi M. Weekly schedule of docetaxel in breast cancer: evaluation of response and toxicity. Breast Cancer (Tokyo, Japan). 10: 10-4. PMID 12525757 DOI: 10.1007/BF02967619  0.347
2002 Nakanishi C, Toi M, Saji S, Bando H. [Current indications for mastectomy in patients with breast cancer]. Nihon Geka Gakkai Zasshi. 103: 821-4. PMID 12478859  0.387
2002 Watanabe T, Sano M, Toi M, Saeki T, Kanda K, Miura S, Inaji H, Sono H, Saeki H, Nishimura R, Fujita Y. [Late phase II study of exemestane in postmenopausal patients with breast cancer resistant to anti-estrogenic agents]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 29: 1211-21. PMID 12146002  0.312
2002 Tominaga T, Toi M, Ohashi Y, Abe O. Prognostic and predictive value of thymidine phosphorylase activity in early-stage breast cancer patients. Clinical Breast Cancer. 3: 55-64. PMID 12020396 DOI: 10.3816/cbc.2002.n.012  0.348
2002 Bando H, Matsumoto G, Bando M, Muta M, Ogawa T, Funata N, Nishihira J, Koike M, Toi M. Expression of macrophage migration inhibitory factor in human breast cancer: association with nodal spread. Japanese Journal of Cancer Research : Gann. 93: 389-96. PMID 11985788  0.409
2002 Tominaga T, Toi M, Abe O, Ohashi Y, Uchino J, Hayasaka H, Abe R, Izuo M, Enomoto K, Watanabe H, Yoshida M, Taguchi T, Koyama H, Senoo T, Toge T, et al. The effect of adjuvant 5'-deoxy-5-fluorouridine in early stage breast cancer patients: results from a multicenter randomized controlled trial. International Journal of Oncology. 20: 517-25. PMID 11836563  0.401
2002 Kuroi K, Tanaka C, Bando H, Saji S, Hayashi K, Toi M. [Efficacy of biweekly paclitaxel therapy in advanced or recurrent breast cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 29: 55-60. PMID 11816478  0.33
2002 Kanzaki A, Toi M, Neamati N, Miyashita H, Oubu M, Nakayama K, Bando H, Ogawa K, Mutoh M, Mori S, Terada K, Sugiyama T, Fukumoto M, Takebayashi Y. Copper-transporting P-type adenosine triphosphatase (ATP7B) is expressed in human breast carcinoma. Japanese Journal of Cancer Research : Gann. 93: 70-7. PMID 11802810 DOI: 10.1111/J.1349-7006.2002.Tb01202.X  0.341
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